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  1. Content type: Research article

    Community-acquired pneumonia (CAP) is a common condition with high mortality, morbidity and healthcare costs. This study aimed to determine whether clinical pathway (CP) implementation in different hospitals i...

    Authors: Liping Zhu, Jie Bai, Yongcong Chen and Di Xue

    Citation: BMC Infectious Diseases 2018 18:471

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  2. Content type: Research article

    Hand, foot, and mouth disease (HFMD) is a viral disease caused by human enteroviruses. Although HFMD reinfection is common, studies investigating this phenomenon are insufficient.

    Authors: Chao Shi, Juan Liu, Ping Shi, Hong Ji, Yuan Shen and Yan-Hua Qian

    Citation: BMC Infectious Diseases 2018 18:472

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  3. Content type: Case report

    Trichosporon species may colonize the skin, respiratory tract and gastrointestinal tract of human beings. The yeast is recognized as etiological agent of white piedra, a superficial mycosis. Nevertheless, immunoc...

    Authors: Eveline Pipolo Milan, Walicyranison Plinio Silva-Rocha, Jéssica Jacinto Salviano de Almeida, Tatiane Uetti Gomes Fernandes, André Luciano de Araújo Prudente, Matheus Firmino de Azevedo, Elaine Cristina Francisco, Analy Salles de Azevedo Melo, Arnaldo Lopes Colombo and Guilherme Maranhão Chaves

    Citation: BMC Infectious Diseases 2018 18:470

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  4. Content type: Research article

    Zimbabwe is on track towards achieving viral suppression among adults (87%). However, adolescents have only achieved 44% by 2016. In Harare city, 57% of adolescents had attained viral suppression after 12 mont...

    Authors: Zvanaka Sithole, Elizabeth Mbizvo, Prosper Chonzi, More Mungati, Tsitsi Patience Juru, Gerald Shambira, Notion Tafara Gombe and Mufuta Tshimanga

    Citation: BMC Infectious Diseases 2018 18:469

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  6. Content type: Research article

    To prevent cross infection the surgical team perform preoperative hand disinfection before dressed in surgical gowns and gloves. Preoperative hand disinfection does not make hands sterile and the surgical glov...

    Authors: Camilla Wistrand, Bo Söderquist, Karin Falk-Brynhildsen and Ulrica Nilsson

    Citation: BMC Infectious Diseases 2018 18:466

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  7. Content type: Research article

    Most guidelines recommend 6 to 12 weeks of parenteral antibiotic treatment for pyogenic spondylodiscitis. When surgical debridement is adequately performed, further intravenous antibiotic treatment duration ca...

    Authors: Yun-Da Li, Chak-Bor Wong, Tsung-Ting Tsai, Po-Liang Lai, Chi-Chien Niu, Lih-Huei Chen and Tsai-Sheng Fu

    Citation: BMC Infectious Diseases 2018 18:468

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  8. Content type: Research article

    HIV prevalence among men who have sex with men (MSM) in China is rising rapidly, and unprotected anal intercourse (UAI) is associated with HIV transmission. Recent research has shown that associations between ...

    Authors: Xin Wang, Zezhou Wang, Xueqin Jiang, Rui Li, Ying Wang, Gang Xu, Huachun Zou and Yong Cai

    Citation: BMC Infectious Diseases 2018 18:465

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  9. Content type: Research article

    Helicobacter pylori is a major aetiologic agent associated with gastritis. H. pylori infections increase the expression of the Toll-like receptor (TLR), which in turn modulates the expression of microRNA (miRNA)-...

    Authors: Ana Caren Cortés-Márquez, Sandra Mendoza-Elizalde, Francisco Arenas-Huertero, Jimena Trillo-Tinoco, Pedro Valencia-Mayoral, Alejandra Consuelo-Sánchez, Jonathan Zarate-Franco, Ada Ruth Dionicio-Avendaño, José de Jesús Herrera-Esquivel, Elio Germán Recinos-Carrera, Christian Colín-Valverde, Sandra Rivera-Gutiérrez, Alfonso Reyes-López, Juan Carlos Vigueras-Galindo and Norma Velázquez-Guadarrama

    Citation: BMC Infectious Diseases 2018 18:463

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  10. Content type: Research article

    Previous studies reported HIV infection alters the distribution and function of γδ T cells and their subsets. γδ T phenotypes in healthy and diseased individuals has received little attention in Ethiopia. We c...

    Authors: Mikias Negash, Aster Tsegaye, Liya Wassie and Rawleigh Howe

    Citation: BMC Infectious Diseases 2018 18:464

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  11. Content type: Research article

    As direct acting antiviral (DAA) therapy is progressively rolled out for patients with hepatitis C virus (HCV) infection, careful scrutiny of HCV epidemiology, diagnostic testing, and access to care is crucial...

    Authors: Emily Adland, Gerald Jesuthasan, Louise Downs, Victoria Wharton, Gemma Wilde, Anna L. McNaughton, Jane Collier, Eleanor Barnes, Paul Klenerman, Monique Andersson, Katie Jeffery and Philippa C. Matthews

    Citation: BMC Infectious Diseases 2018 18:461

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  12. Content type: Research article

    Multiplex real-time polymerase chain reaction assays have improved diagnostic sensitivity for a wide range of pathogens. However, co-detection of multiple agents and bacterial colonization make it difficult to...

    Authors: Clarence C. Tam, Vittoria Offeddu, Kathryn B. Anderson, Alden L. Weg, Louis R. Macareo, Damon W. Ellison, Ram Rangsin, Stefan Fernandez, Robert V. Gibbons, In-Kyu Yoon and Sriluck Simasathien

    Citation: BMC Infectious Diseases 2018 18:462

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  13. Content type: Research article

    Microbial contamination of hospital environment, especially in operating theatres (OT) and other specialized units has greatly contributed to continuous and multiple exposure to nosocomial infections by patien...

    Authors: Sandra Matinyi, Muwanguzi Enoch, Deborah Akia, Valentine Byaruhanga, Edson Masereka, Isaac Ekeu and Collins Atuheire

    Citation: BMC Infectious Diseases 2018 18:460

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  14. Content type: Research article

    Acute Respiratory Infections (ARI) are common causes of febrile illnesses in many settings in Senegal. These infections are usually managed presumptively due to lack of appropriate diagnostic tools. This situa...

    Authors: Roger C. Tine, Léon A. Ndiaye, Mbayame N. Niang, Davy E. Kiori, Ndongo Dia, Oumar Gaye and Hélène Broutin

    Citation: BMC Infectious Diseases 2018 18:459

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  15. Content type: Research article

    Extrapulmonary tuberculosis (EPTB) is a heterogeneous disease, and diagnosis is sometimes difficult. We investigated the diagnostic performance of the QuantiFERON-TB Gold assay (QFT-GIT) according to sites of ...

    Authors: Youn Jeong Kim, Ji Young Kang, Sang Il Kim, Mee Soo Chang, Yang Ree Kim and Yeon Joon Park

    Citation: BMC Infectious Diseases 2018 18:457

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  16. Content type: Research article

    This study aimed to investigate the occurrence of Cytomegalovirus (CMV) DNA in the Bronchoalveolar lavage fluid (BALF) of children with recurrent wheezing and to identify associations with certain patient clin...

    Authors: Huiming Sun, Shuxiang Li, Yongdong Yan, Zhengrong Chen, Yuqing Wang, Chuangli Hao and Wei Ji

    Citation: BMC Infectious Diseases 2018 18:458

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  17. Content type: Research article

    Tungiasis is an ectoparasitic infestation, which still has public health importance in deprived populations of developing countries. Data on the prevalence and risk factors of tungiasis is rare in Ethiopia. He...

    Authors: Mekonnen Girma, Ayalew Astatkie and Solomon Asnake

    Citation: BMC Infectious Diseases 2018 18:456

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  18. Content type: Case report

    Burkholderia pseudomallei is the causative agent of melioidosis, which is a potentially life threatening disease endemic in Southeast Asian countries. In Malaysia, cystic fibrosis (CF) is an uncommon condition. T...

    Authors: Vanitha Mariappan, Surendran Thavagnanam, Kumutha Malar Vellasamy, Cindy Ju Shuan Teh, Nadia Atiya, Sasheela Ponnampalavanar and Jamuna Vadivelu

    Citation: BMC Infectious Diseases 2018 18:455

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  19. Content type: Case report

    Members of Shewanella species are opportunistic pathogens that are found in marine environments. Currently more than sixty species have been identified, whereas the most commonly clinical cases associated with Sh...

    Authors: Furong Zhang, Yujie Fang, Feng Pang, Shengnan Liang, Xin Lu, Biao Kan, Jianguo Xu, Jinxing Zhao, Yinju Du and Duochun Wang

    Citation: BMC Infectious Diseases 2018 18:454

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  20. Content type: Research article

    The impact of different classes of microbial pathogens on mortality in severe community-acquired pneumonia is not well elucidated. Previous studies have shown significant variation in the incidence of viral, b...

    Authors: Jessica Quah, Boran Jiang, Poh Choo Tan, Chuin Siau and Thean Yen Tan

    Citation: BMC Infectious Diseases 2018 18:451

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  21. Content type: Research article

    It is not fully explained why some active tuberculosis patients show negative interferon-γ release assays (IGRAs). In this study, we tried to explore associations of IGRAs with the characteristics of periphera...

    Authors: Liping Yan, Hongbo Shen and Heping Xiao

    Citation: BMC Infectious Diseases 2018 18:453

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  22. Content type: Case report

    Melioidosis is endemic in Southeast Asia and northern Australia. Infection usually follows percutaneous inoculation or inhalation or ingestion of the causative bacterium, Burkholderia pseudomallei, which is prese...

    Authors: X. Y. Li, B. X. Ke, C. N. Chen, H. L. Xiao, M. Z. Liu, Y. C. Xiong, R. Bai, J. D. Chen and C. W. Ke

    Citation: BMC Infectious Diseases 2018 18:452

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  23. Content type: Research article

    Tuberculosis remains a serious threat to human health as an infectious disease in China. Henan, a most populated province in China, has a high incidence of tuberculosis (TB). Though the genetic diversity of Mycob...

    Authors: Jie Shi, Danwei Zheng, Yankun Zhu, Xiaoguang Ma, Shaohua Wang, Hui Li and Jin Xing

    Citation: BMC Infectious Diseases 2018 18:447

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  24. Content type: Research article

    Despite the high sustained virological response rates achieved with current directly-acting antiviral agents (DAAs) against hepatitis C virus (HCV), around 5–10% of treated patients do not respond to current a...

    Authors: María Eugenia Soria, Josep Gregori, Qian Chen, Damir García-Cehic, Meritxell Llorens, Ana I. de Ávila, Nathan M. Beach, Esteban Domingo, Francisco Rodríguez-Frías, María Buti, Rafael Esteban, Juan Ignacio Esteban, Josep Quer and Celia Perales

    Citation: BMC Infectious Diseases 2018 18:446

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  25. Content type: Research article

    Influenza is an acute viral disease of the respiratory tract which is characterized by fever, headache, myalgia, prostration, coryza, sore throat and cough. Globally, an estimated 3 to 5 million cases of sever...

    Authors: Abyot Bekele Woyessa, Mesfin Mengesha, Desalegn Belay, Adamu Tayachew, Workenesh Ayele, Berhane Beyene, Woubayehu Kassa, Etsehiwot Zemelak, Gelila Demissie, Berhanu Amare, Lucy Boulanger, Carolina Granados, Thelma Williams, Israel Tareke, Soatiana Rajatonirina and Daddi Jima

    Citation: BMC Infectious Diseases 2018 18:449

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  26. Content type: Research article

    As countries scale up antiretroviral therapy (ART) for children, innovative strategies to deliver quality services to children are needed. Differentiated ART delivery models have been successful in adults, but...

    Authors: Jason M. Bacha, Lynda C. Aririguzo, Veronica Mng’ong’o, Beatrice Malingoti, Richard S. Wanless, Katherine Ngo, Liane R. Campbell and Gordon E. Schutze

    Citation: BMC Infectious Diseases 2018 18:448

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  27. Content type: Research article

    Diarrhea is a major source of morbidity and mortality among young children in low-income and middle-income countries. Human adenoviruses (HAdV), particular HAdV species F (40, 41) has been recognized as import...

    Authors: Fang-zhou Qiu, Xin-xin Shen, Gui-xia Li, Li Zhao, Chen Chen, Su-xia Duan, Jing-yun Guo, Meng-chuan Zhao, Teng-fei Yan, Ju-Ju Qi, Le Wang, Zhi-shan Feng and Xue-jun Ma

    Citation: BMC Infectious Diseases 2018 18:450

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  29. Content type: Research article

    Clostridium difficile infection (CDI) is a major cause of morbidity and mortality in North America and Europe. The aim of this study was to identify epidemiologically-confirmed cases of community-acquired (CA)-CD...

    Authors: Christina S. Thornton, Joseph E. Rubin, Alexander L. Greninger, Gisele Peirano, Charles Y. Chiu and Dylan R. Pillai

    Citation: BMC Infectious Diseases 2018 18:443

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  30. Content type: Research article

    Multidrug resistant-tuberculosis (MDR-TB) is a major global health concern. Its treatment requires toxic medications, is longer and costlier than drug-susceptible TB, and often results in productivity losses a...

    Authors: Lisa Kawatsu, Kazuhiro Uchimura, Kiyohiko Izumi, Akihiro Ohkado and Takashi Yoshiyama

    Citation: BMC Infectious Diseases 2018 18:445

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  31. Content type: Research article

    Chronic rhinosinusitis is an inflammatory disorder in which the role of bacteria remains uncertain. While sinus outflow obstruction is often an initiating event, mucosal inflammation and dysbiosis may persist ...

    Authors: Ioannis Koutsourelakis, Ashleigh Halderman, Syed Khalil, Lauren E. Hittle, Emmanuel F. Mongodin and Andrew P. Lane

    Citation: BMC Infectious Diseases 2018 18:441

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  32. Content type: Research article

    Psittacosis outbreak investigations require rapid identification of cases in order to trace possible sources and perform public health risk assessments. In recent outbreaks in the Netherlands, such investigati...

    Authors: Annelies A. Nieuwenhuizen, Frederika Dijkstra, Daan W. Notermans and Wim van der Hoek

    Citation: BMC Infectious Diseases 2018 18:442

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  33. Content type: Research article

    To compare the risk of severe hepatotoxicity with anidulafungin versus caspofungin and micafungin in hospitalized adults.

    Authors: Francis Vekeman, Lisa Weiss, Jalal Aram, Raluca Ionescu-Ittu, Shahrzad Moosavi, Yongling Xiao, Wendy Y. Cheng, Rachel H. Bhak, Margaret Tawadrous, M. Rita Capparella, Philippe Montravers and Mei Sheng Duh

    Citation: BMC Infectious Diseases 2018 18:438

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  34. Content type: Research article

    Streptococcus pneumoniae is a commensal of the human upper respiratory tract and a major cause of morbidity and mortality worldwide. This paper presents the distribution of serotypes and antimicrobial resistance ...

    Authors: Rachid Y. Yahiaoui, Hester J. Bootsma, Casper D. J. den Heijer, Gerlinde N. Pluister, W. John Paget, Peter Spreeuwenberg, Krzysztof Trzcinski and Ellen E. Stobberingh

    Citation: BMC Infectious Diseases 2018 18:440

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  35. Content type: Research article

    Genetic diversity in Plasmodium falciparum (P. falciparum) parasites is a major hurdle to the control of malaria. This study monitored changes in the genetic diversity and the multiplicity of P. falciparum parasi...

    Authors: Joshua Adjah, Bless Fiadzoe, Ruth Ayanful-Torgby and Linda E. Amoah

    Citation: BMC Infectious Diseases 2018 18:432

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  36. Content type: Research article

    Pet ownership in China has been steadily increasing over recent years. However, the risk of pet-associated zoonotic infection with the protozoan parasite Toxoplasma gondii remains poorly defined.

    Authors: Wei Cong, Hany M. Elsheikha, Na Zhou, Peng Peng, Si-Yuan Qin, Qing-Feng Meng and Ai-Dong Qian

    Citation: BMC Infectious Diseases 2018 18:430

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  37. Content type: Research article

    Epidemiological information on the burden of various parasitic infections and associated factors in different localities is indispensable to develop appropriate control and prevention measures as well as to mo...

    Authors: Getaneh Alemu, Zeleke Aschalew and Eshetu Zerihun

    Citation: BMC Infectious Diseases 2018 18:435

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  38. Content type: Case report

    Human immunodeficiency virus (HIV) infection has been recognized as a risk factor for both ischemic and hemorrhagic stroke among young adults. However, information on the optimal management of HIV patients pre...

    Authors: Ping Liu, Min Wu, Ning Zhang, Chunyou Chen, Bing Xiong and Xiaoying Zhang

    Citation: BMC Infectious Diseases 2018 18:434

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  39. Content type: Research article

    International and national travelling has made the rapid spread of infectious diseases possible. Little information is available on the role of major traffic hubs, such as airports, in the transmission of resp...

    Authors: Niina Ikonen, Carita Savolainen-Kopra, Joanne E. Enstone, Ilpo Kulmala, Pertti Pasanen, Anniina Salmela, Satu Salo, Jonathan S. Nguyen-Van-Tam and Petri Ruutu

    Citation: BMC Infectious Diseases 2018 18:437

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  41. Content type: Case report

    Septic cardiomyopathy represents cardiac impairment in sepsis and is a part of systemic involvement in sepsis. Cytokine storm is responsible for septic shock and for myocardial dysfunction of potentially rever...

    Authors: Andreja Sinkovic, Barbara Kit and Andrej Markota

    Citation: BMC Infectious Diseases 2018 18:433

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  42. Content type: Research article

    Increasing numbers of refractory or severe, even fatal, cases of Mycoplasma pneumoniae infections have been reported in recent years. Excessive inflammatory responses play a vital role in the pathogenesis of refr...

    Authors: Ying Ding, Chu Chu, Yuqin Li, Gen Li, Xiaoli Lei, Weifang Zhou and Zhengrong Chen

    Citation: BMC Infectious Diseases 2018 18:439

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  43. Content type: Research article

    Despite the widespread availability of pneumococcal vaccines, rates of pneumococcal disease are disproportionately high in adults with chronic and immunocompromising conditions. This study investigated pneumoc...

    Authors: Dongmu Zhang, Tanaz Petigara and Xiaoqin Yang

    Citation: BMC Infectious Diseases 2018 18:436

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  44. Content type: Research article

    Necrotizing soft tissue infection is the most serious of all soft tissue infections. The patient’s life is dependent on prompt diagnosis and aggressive treatment. Diagnostic delays are related to increased mor...

    Authors: Annette Erichsen Andersson, Ingrid Egerod, Vibeke E. Knudsen and Ann-Mari Fagerdahl

    Citation: BMC Infectious Diseases 2018 18:429

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  45. Content type: Research article

    Chronic diseases, chiefly cancers and circulatory system diseases (CSDs), have become the leading non-AIDS-related causes of death among HIV-infected people, as in the general population. After our previous re...

    Authors: Barbara Suligoi, Saverio Virdone, Martina Taborelli, Luisa Frova, Enrico Grande, Francesco Grippo, Marilena Pappagallo, Vincenza Regine, Lucia Pugliese, Diego Serraino and Antonella Zucchetto

    Citation: BMC Infectious Diseases 2018 18:428

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  46. Content type: Research article

    Tuberculosis (TB), especially extrapulmonary tuberculosis (EPTB), is an important cause of fever of unknown origin (FUO) in TB-burdened areas. Little information is known about patients with EPTB with clinical...

    Authors: Jeong-Han Kim, Eu Suk Kim, Kang-Il Jun, Hyun gul Jung, Ji Hwan Bang, Pyeong Gyun Choe, Wan Beom Park, Kyoung-Ho Song, Hong Bin Kim, Nam Joong Kim, Myoung-don Oh and Sang-Won Park

    Citation: BMC Infectious Diseases 2018 18:426

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  47. Content type: Case report

    Incidence of Dengue infection is on the increase in Sri Lanka with it being associated with significant maternal and neonatal morbidity in pregnancy.

    Authors: B. V. K. M. Bopeththa, Sardha Hemapriya, K. K. Gayan Niranga and Danushka S. K. Kotigala

    Citation: BMC Infectious Diseases 2018 18:427

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  48. Content type: Research article

    Since the early 90’s antiretroviral drugs have been available at King Faisal Specialist Hospital and Research Centre (KFSH&RC), a referral hospital in Riyadh, Saudi Arabia, for the treatment of both adults and...

    Authors: Maha Al-Mozaini, Tahani Alrahbeni, Reem Al-Mograbi and Abdulrahman Alrajhi

    Citation: BMC Infectious Diseases 2018 18:425

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  49. Content type: Research article

    Infection with Chlamydia trachomatis (Ct) is the most commonly reported sexually transmitted infection in Europe. In Germany, Ct screening is offered free of charge to pregnant women since 1995 and to women < 25 ...

    Authors: Alexandra Sarah Lang, Matthias an der Heiden, Klaus Jansen, Andrea Sailer, Viviane Bremer and Sandra Dudareva

    Citation: BMC Infectious Diseases 2018 18:424

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  50. Content type: Research article

    The major factors contributing for nerve damage and permanent disabilities in leprosy are type 1 or reversal reactions (RR) and type 2 or erythema nodosum leprosum (ENL). Gene profiling of leprosy reactions ha...

    Authors: Jamile Leão Rêgo, Nadja de Lima Santana, Paulo Roberto Lima Machado, Marcelo Ribeiro-Alves, Thiago Gomes de Toledo-Pinto, Léa Cristina Castellucci and Milton Ozório Moraes

    Citation: BMC Infectious Diseases 2018 18:422

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