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  1. Content type: Research article

    Osteomyelitis is often challenging to treat. This analysis examined the clinical experience of patients with gram-positive osteomyelitis treated with ceftaroline fosamil in the phase 4 Clinical Assessment Prog...

    Authors: Leonard B. Johnson, Ananthakrishnan Ramani and David J. Guervil

    Citation: BMC Infectious Diseases 2019 19:183

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  2. Content type: Debate

    Taenia solium taeniosis/cysticercosis is a public health and agricultural problem, especially in low-income countries, and has been ranked the top foodborne parasitic hazard globally. In 2012, the World Health Or...

    Authors: Uffe Christian Braae, Sarah Gabriël, Chiara Trevisan, Lian F. Thomas, Pascal Magnussen, Bernadette Abela-Ridder, Helena Ngowi and Maria Vang Johansen

    Citation: BMC Infectious Diseases 2019 19:182

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  3. Content type: Research article

    Detecting the onset of influenza epidemic is important for epidemiological surveillance and for investigating the factors driving spatiotemporal transmission patterns. Most approaches define the epidemic onset...

    Authors: Jun Cai, Bing Zhang, Bo Xu, Karen Kie Yan Chan, Gerardo Chowell, Huaiyu Tian and Bing Xu

    Citation: BMC Infectious Diseases 2019 19:181

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  4. Content type: Research article

    In spite of an alarmingly high tuberculosis (TB) burden amongst the Saharia tribe of central India, there is hardly any study to investigate the impact of DOTS implementation on the magnitude of tuberculosis d...

    Authors: V. G. Rao, J. Bhat, R. Yadav, R. K. Sharma and M. Muniyandi

    Citation: BMC Infectious Diseases 2019 19:180

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  5. Content type: Research article

    Streptococcus agalactiae or Group B Streptococcus (GBS) is the leading cause of neonatal morbidity and mortality resulting in septicaemia, bacteraemia and meningitis. Long term problems in children range from los...

    Authors: Munyaradzi Mukesi, Benson C. Iweriebor, Larry C. Obi, Uchechukwu U. Nwodo, Sylvester R. Moyo and Anthony I. Okoh

    Citation: BMC Infectious Diseases 2019 19:179

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  6. Content type: Research article

    In January 2011, there was an outbreak of Panton-Valentine Leukocidin-positive methicillin-sensitive Staphylococcus aureus (PVL-MSSA) infection in a neonatal unit (NNU).

    Authors: G. Gopal Rao, R. Batura, R. Nicholl, F. Coogan, B. Patel, P. Bassett and A. M. Kearns

    Citation: BMC Infectious Diseases 2019 19:178

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  7. Content type: Research article

    The emergence of norovirus genotype GII.4 variants has been associated with gastroenteritis pandemics worldwide, prompting molecular surveillance for early detection of novel strains. In this study, we aimed t...

    Authors: Maria E. Hasing, Bonita E. Lee, Yuanyuan Qiu, Ming Xia, Kanti Pabbaraju, Anita Wong, Graham Tipples, Xi Jiang and Xiaoli L. Pang

    Citation: BMC Infectious Diseases 2019 19:177

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  8. Content type: Case report

    Melioidosis is a life-threatening infectious disease that is caused by gram negative bacteria Burkholderia pseudomallei. This bacteria occurs as an environmental saprophyte typically in endemic regions of south-e...

    Authors: Neha Shrestha, Mahesh Adhikari, Vivek Pant, Suman Baral, Anjan Shrestha, Buddha Basnyat, Sangita Sharma and Jeevan Bahadur Sherchand

    Citation: BMC Infectious Diseases 2019 19:176

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  9. Content type: Research article

    Solithromycin, the fourth generation of ketolides, has been demonstrated potent antibacterial effect against commonly-isolated gram-positive strains. However, Staphylococcus aureus (S. aureus) strains with a high...

    Authors: Weiming Yao, Guangjian Xu, Duoyun Li, Bing Bai, Hongyan Wang, Hang Cheng, Jinxin Zheng, Xiang Sun, Zhiwei Lin, Qiwen Deng and Zhijian Yu

    Citation: BMC Infectious Diseases 2019 19:175

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  10. Content type: Research article

    Severe fever with thrombocytopenia syndrome (SFTS) is emerging in Asian 3 countries, China, Japan and Korea, which are scrub typhus endemic areas, and its incidence is increasing. As the two infections overlap...

    Authors: Sang-Won Park, Chang-Seop Lee, Jeong-Han Kim, In-Gyu Bae, Chisook Moon, Yee Gyung Kwak, Baek-Nam Kim, Jae Hoon Lee, Seong Yeol Ryu, Hee-Chang Jang, Jian Hur, Jae-Bum Jun, Younghee Jung, Hyun-Ha Chang, Young Keun Kim, Jeong-Hwan Hwang…

    Citation: BMC Infectious Diseases 2019 19:174

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  11. Content type: Research article

    A novel method, termed loop-mediated isothermal amplification (LAMP), was developed by Notomi et al. (2000). Individually published results have been reported that this technology has been successfully applied...

    Authors: Zi-Hong Cai, Yuan-Yuan Dai, Lin-Yan Huang, Wen-Sheng Zhang and Xu-Guang Guo

    Citation: BMC Infectious Diseases 2019 19:173

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  12. Content type: Research article

    In the event of a shigellosis outbreak in a childcare setting, exclusion policies are typically applied to afflicted children to limit shigellosis transmission. However, there is scarce evidence of their impact.

    Authors: Cristina Carias, Eduardo A. Undurraga, Jacqueline Hurd, Emily B. Kahn, Martin I. Meltzer and Anna Bowen

    Citation: BMC Infectious Diseases 2019 19:172

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  14. Content type: Research article

    Community- associated methicillin resistant Staphylococcus aureus (CA-MRSA) cause serious infections and rates continue to rise worldwide. Use of geocoded electronic health record (EHR) data to prevent spread of ...

    Authors: Lilly Cheng Immergluck, Traci Leong, Kevin Matthews, Khusdeep Malhotra, Trisha Chan Parker, Fatima Ali, Robert C. Jerris and George S. Rust

    Citation: BMC Infectious Diseases 2019 19:170

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  16. Content type: Research article

    The etiology and epidemiology of acute otitis media (AOM) are poorly understood in China. This study aimed to describe the etiology of AOM and the phenotypic and molecular characteristics of AOM-causing Streptoco...

    Authors: Jinjian Fu, Ling Li, Zhuoxin Liang, Shaolin Xu, Nan Lin, Peixu Qin, Xiaohua Ye and Eric McGrath

    Citation: BMC Infectious Diseases 2019 19:168

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  17. Content type: Research article

    To evaluate the in vitro activities of plazomicin and comparator aminoglycosides and elucidate the underlying aminoglycoside resistance mechanisms among carbapenemase-producing K. pneumoniae isolates collected du...

    Authors: Irene Galani, Konstantina Nafplioti, Panagiota Adamou, Ilias Karaiskos, Helen Giamarellou and Maria Souli

    Citation: BMC Infectious Diseases 2019 19:167

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  18. Content type: Case report

    Helicobacter cinaedi is a microaerobic Gram-negative spiral-shaped bacterium that causes enteritis, cellulitis, and bacteremia in both immunocompromised and immunocompetent patients. While there have been increas...

    Authors: Tomohiro Takehara, Tetsuo Tani, Ken Yajima, Mako Watanabe, Yoshihito Otsuka and Hidefumi Koh

    Citation: BMC Infectious Diseases 2019 19:166

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  19. Content type: Research article

    Prevalence of schistosomiasis is high among children under five years in Uganda. Schistosomiasis control efforts over time have included periodic mass treatments in endemic areas for adults and school going ch...

    Authors: Simon Peter Sebina Kibira, John C. Ssempebwa, Ronald Ssenyonga, Scott Radloff and Fredrick Edward Makumbi

    Citation: BMC Infectious Diseases 2019 19:165

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  20. Content type: Technical advance

    Herpes simplex virus type 1 (HSV1), establishes life-long latency and can cause symptoms during both first-time infection and later reactivation. The aim of the present study was to describe a protocol to gene...

    Authors: Jan Olsson, Jörgen Johansson, Emma Honkala, Bert Blomqvist, Eloise Kok, Bodil Weidung, Hugo Lövheim and Fredrik Elgh

    Citation: BMC Infectious Diseases 2019 19:164

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  21. Content type: Research article

    Bacterial resistance to first line antibiotics used to treat community-onset urinary tract infections (UTIs) continues to emerge. We sought to determine the association between extended-spectrum cephalosporin ...

    Authors: Judith A. Anesi, Ebbing Lautenbach, Irving Nachamkin, Charles Garrigan, Warren B. Bilker, Jacqueline Omorogbe, Lois Dankwa, Mary Wheeler, Pam Tolomeo and Jennifer H. Han

    Citation: BMC Infectious Diseases 2019 19:163

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  22. Content type: Research article

    Influenza and pneumococcal vaccine uptake in the older population aged 65 years or over of Hong Kong dramatically increased since the 2003 SARS outbreak. This study is aimed to evaluate the impact of increased...

    Authors: Lin Yang, King Pan Chan, Chit Ming Wong, Susan Shui Seng Chiu, Ricardo J. Soares Magalhaes, Thuan Quoc Thach, Joseph Syrial Malik Peiris, Archie C. A. Clements and Wenbiao Hu

    Citation: BMC Infectious Diseases 2019 19:162

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  23. Content type: Research article

    A reduction in duration of antibiotic therapy is crucial in minimizing the development of antimicrobial resistance, drug-related side effects and health care costs. The minimal effective duration of antimicrob...

    Authors: Janneke Evelyne Stalenhoef, Cees van Nieuwkoop, Darius Cameron Wilson, Willize Elizabeth van der Starre, Tanny J. K. van der Reijden, Nathalie Manon Delfos, Eliane Madeleine Sophie Leyten, Ted Koster, Hans Christiaan Ablij, Johannes (Jan) Willem van ‘t Wout and Jaap Tamino van Dissel

    Citation: BMC Infectious Diseases 2019 19:161

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  24. Content type: Research article

    To improve national influenza vaccination recommendations, additional data on influenza A and B virus circulation are needed. Here, we describe the circulation of influenza A and B in the Czech Republic during...

    Authors: Martina Havlickova, Sophie Druelles, Helena Jirincova, Radomira Limberkova, Alexander Nagy, Anvar Rasuli and Jan Kyncl

    Citation: BMC Infectious Diseases 2019 19:160

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  25. Content type: Research article

    Egypt ranks fifth for the burden of viral hepatitis worldwide. As part of Egypt’s renewed national strategy for the elimination of viral hepatitis, surveillance for acute viral hepatitis (AVH) was re-establish...

    Authors: Maha Talaat, Salma Afifi, Erik J. Reaves, Hanaa Abu Elsood, Amany El-Gohary, Samir Refaey, Radi Hammad, Mostafa Abdel Fadeel and Amr Kandeel

    Citation: BMC Infectious Diseases 2019 19:159

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  26. Content type: Research article

    Clinical characteristics (taxonomy, virulence genes and antimicrobial resistance ) of Aeromonas in isolated from extra-intestinal and intestinal infections were investigated to describe epidemiology, associated v...

    Authors: Yanyan Zhou, Li Yu, Zheng Nan, Pingping Zhang, Biao Kan, Donghui Yan and Jianrong Su

    Citation: BMC Infectious Diseases 2019 19:158

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  27. Content type: Research article

    Helicobacter pylori infection is associated with several extragastric conditions including dyslipidemia and metabolic syndrome. This study aimed to investigate additional metabolic parameters associated with H. p...

    Authors: Miao-Miao Zhao, Jeremy Krebs, Xi Cao, Jing Cui, Dong-Ning Chen, Yu Li, Lin Hua, Jim Mann and Jin-Kui Yang

    Citation: BMC Infectious Diseases 2019 19:157

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  28. Content type: Research article

    HIV-associated neurocognitive disorder (HAND) remains prevalent in the era of combination antiretroviral therapy (cART). The prevalence of HAND in Hong Kong is not known.

    Authors: Fiona C.C. Chan, Phillip Chan, Iris Chan, Andrew Chan, Tommy H. C. Tang, Wilson Lam, W. C. Fong, M. P. Lee, Patrick Li and Germaine H. F. Chan

    Citation: BMC Infectious Diseases 2019 19:156

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  29. Content type: Research article

    Uncomplicated urinary tract infection (uUTI) is common and a majority of patients are prescribed antibiotics. There is little knowledge about antibiotic resistance in urine samples from patients with uUTI in p...

    Authors: Helena Kornfält Isberg, Eva Melander, Katarina Hedin, Sigvard Mölstad and Anders Beckman

    Citation: BMC Infectious Diseases 2019 19:155

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  30. Content type: Research article

    TB outbreaks in educational institutions can result in significant transmission and pose a considerable threat to TB control. Investigation using traditional microbiological and epidemiological tools can lead ...

    Authors: Simon Packer, Claire Green, Ellen Brooks-Pollock, Katerina Chaintarli, Sarah Harrison and Charles R. Beck

    Citation: BMC Infectious Diseases 2019 19:154

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  31. Content type: Research article

    The potential effect of the inactivated hantavirus vaccine (IHV) remains controversial; however, it appears to be moderately effective for patients at high risk of hemorrhagic fever with renal syndrome (HFRS)....

    Authors: Yohan Park

    Citation: BMC Infectious Diseases 2019 19:153

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  32. Content type: Research article

    A major outbreak of the Zika virus (ZIKV) has been reported in Brazil in 2015. Since then, it spread further to other countries in the Americas and resulted in declaration of the Public Health Emergency of Int...

    Authors: Yuan Liang Woon, Mei Fong Lim, Tg Rogayah Tg Abd Rashid, Ravindran Thayan, Suresh Kumar Chidambaram, Syed Sharizman Syed Abdul Rahim, Rose Nani Mudin and Sheamini Sivasampu

    Citation: BMC Infectious Diseases 2019 19:152

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  33. Content type: Research article

    Vitamin D levels are associated with the extent of mycobactericidal activity. Interleukin (IL)-15 and IL-32 play roles in the vitamin D-mediated tuberculosis (TB) defense mechanism. Vitamin D induces IL-1β, wh...

    Authors: Yoonki Hong, Youngmi Kim, Jae Jun Lee, Myung Goo Lee, Chang Youl Lee, Youlim Kim, Jeongwon Heo, Seon-Sook Han, Seung-Joon Lee, Woo Jin Kim and Ji Young Hong

    Citation: BMC Infectious Diseases 2019 19:151

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  34. Content type: Research article

    The aim of this study was to evaluate whether Interleukin-6 (IL-6) could be a faster indicator of treatment success in adults with severe sepsis and septic shock compared to procalcitonin (PCT) and C-reactive ...

    Authors: Lorenz Weidhase, Daniel Wellhöfer, Gero Schulze, Thorsten Kaiser, Tim Drogies, Ulrike Wurst and Sirak Petros

    Citation: BMC Infectious Diseases 2019 19:150

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  35. Content type: Research article

    The prognostic capability of the quick Sequential Organ Failure Assessment (qSOFA) bedside scoring tool is uncertain in non-ICU patients with sepsis due to bacteremia given the low number of patients previousl...

    Authors: Emi Minejima, Vanessa Delayo, Mimi Lou, Pamela Ny, Paul Nieberg, Rosemary C. She and Annie Wong-Beringer

    Citation: BMC Infectious Diseases 2019 19:149

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  36. Content type: Research article

    Antimicrobial resistance in Mycoplasma genitalium is rising globally with resultant clinical treatment failure. We investigated the prevalence of mutations in the macrolide and fluoroquinolone resistance-determin...

    Authors: Etienne E. Muller, Mahlape P. Mahlangu, David A. Lewis and Ranmini S. Kularatne

    Citation: BMC Infectious Diseases 2019 19:148

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  37. Content type: Research article

    The relationship between chronic hepatitis B virus (HBV) infection with gestational diabetes mellitus (GDM) remains unclear. This study aimed to identify the association between maternal HBsAg-positive status ...

    Authors: Songxu Peng, Zhihua Wan, Xiaofang Lin, Xiu Li and Yukai Du

    Citation: BMC Infectious Diseases 2019 19:147

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  38. Content type: Research article

    Loiasis is a vector-borne parasitic disease due to Loa loa and transmitted to humans by tabanids of the genus Chrysops. Loiasis has been historically considered as the second or third most common reason for medic...

    Authors: Aude E. Mogoung-Wafo, Hugues C. Nana-Djeunga, André Domche, Floribert Fossuo-Thotchum, Jean Bopda, Steve Mbickmen-Tchana, Honoré Djomo-Kamga and Joseph Kamgno

    Citation: BMC Infectious Diseases 2019 19:146

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  39. Content type: Research article

    To determine the epidemiology and risk factors for nosocomial infection (NI) in the Respiratory Intensive Care Unit (RICU) of a teaching hospital in Northwest China.

    Authors: Linchuan Wang, Kai-Ha Zhou, Wei Chen, Yan Yu and Si-Fang Feng

    Citation: BMC Infectious Diseases 2019 19:145

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  40. Content type: Technical advance

    Emerging antimicrobial resistance is a significant threat to human health. However, methods for rapidly diagnosing antimicrobial resistance generally require multi-day culture-based assays. Macrolide efflux ge...

    Authors: Megan M. Nelson, Christopher L. Waldron and John R. Bracht

    Citation: BMC Infectious Diseases 2019 19:144

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  41. Content type: Case report

    Melioidosis is an infection caused by Burkholderia pseudomallei, which is more prevalent in the tropics and leads to significant morbidity and mortality. It characteristically produces widespread caseous lesions ...

    Authors: H. L. P. Amarasena, F. H. D. S. Silva, P. M. Y. I. Tilakaratna, S. F. Jayamanne and U. K. Ranawaka

    Citation: BMC Infectious Diseases 2019 19:143

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  42. Content type: Research article

    Among different types of human papillomavirus (HPV), types 16 and 18 were known to be high-risk agents causing mainly cervical cancer. Up to now, the potential of HPV E7 protein has been proved as a diagnostic...

    Authors: Amitis Ramezani, Arezoo Aghakhani, Sepehr Soleymani, Anahita Bavand and Azam Bolhassani

    Citation: BMC Infectious Diseases 2019 19:142

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  43. Content type: Research article

    Cirrhosis-associated immune dysfunction syndrome (CAIDS) has been identified in patients with liver cirrhosis (LC), predisposing them to a wide variety of infections. In patients with LC, healthcare-associated...

    Authors: Tamara Milovanovic, Igor Dumic, Jelena Veličkovic, Milica Stojkovic Lalosevic, Vladimir Nikolic and Ivan Palibrk

    Citation: BMC Infectious Diseases 2019 19:141

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  44. Content type: Case report

    Roseomonas mucosa, as a Gram-negative coccobacilli, is an opportunistic pathogen that has rarely been reported in human infections. Here we describe a case of bacteremia in an infective endocarditis patient with ...

    Authors: Shayuan Shao, Xin Guo, Penghao Guo, Yingpeng Cui and Yili Chen

    Citation: BMC Infectious Diseases 2019 19:140

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  47. Content type: Research article

    Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli are responsible for severe infections worldwide. Whereas their genotypic and pathogenic characteristics are not documented in Democratic Republic...

    Authors: Leonid M. Irenge, Jerome Ambroise, Bertrand Bearzatto, Jean-François Durant, Raphaël B. Chirimwami and Jean-Luc Gala

    Citation: BMC Infectious Diseases 2019 19:137

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  48. Content type: Research article

    Access to qualitative HIV PCRs for early infant diagnosis (EID) is restricted in resource-limited settings due to cost. We hypothesised that pooling of dried blood spots (DBS), defined as combining multiple pa...

    Authors: Cari van Schalkwyk, Jean Maritz, Gert U. van Zyl, Wolfgang Preiser and Alex Welte

    Citation: BMC Infectious Diseases 2019 19:136

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  49. Content type: Research article

    Voriconazole is well established as standard treatment for invasive aspergillosis (IA). In 2017, isavuconazole, a new antifungal from the azole class, with a broader pathogen spectrum, was introduced in Sweden...

    Authors: Lefteris Floros, Daniel Kuessner, Jan Posthumus, Emma Bagshaw and Jan Sjölin

    Citation: BMC Infectious Diseases 2019 19:134

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  50. Content type: Research article

    Empirical treatment of tuberculosis (TB) may be necessary in patients with negative or no Xpert MTB/RIF results. In a context with access to Xpert, we assessed mortality in the 6 months after the initial TB co...

    Authors: Helena Huerga, Gabriella Ferlazzo, Stephen Wanjala, Mathieu Bastard, Paolo Bevilacqua, Elisa Ardizzoni, Joseph Sitienei and Maryline Bonnet

    Citation: BMC Infectious Diseases 2019 19:132

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