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  1. Content type: Research article

    The multidrug therapy (MDT) for leprosy treatment adopted by Brazil in the 1990s was important for reducing leprosy in the country; however, recurrent cases remained problematic. Mechanisms involved in leprosy...

    Authors: Franciely Gomes Gonçalves, Andréa de Faria Fernandes Belone, Patrícia Sammarco Rosa and Gabriel Zorello Laporta

    Citation: BMC Infectious Diseases 2019 19:460

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  2. Content type: Research article

    Studies have shown that the human T-lymphotropic virus 2 (HTLV-2) is endemic in several indigenous populations of the Brazilian Amazon and molecular analyses have shown the exclusive presence of HTLV-2 subtype...

    Authors: Isabel Luís Jocene Braço, Keyla Santos Guedes de Sá, Mishelle Waqasi, Maria Alice Freitas Queiroz, Andréa Nazaré Rangel da Silva, Izaura M. V. Cayres-Vallinoto, Sandra Souza Lima, Marluísa de Oliveira Guimarães Ishak, Ricardo Ishak, João Farias Guerreiro and Antonio Carlos Rosário Vallinoto

    Citation: BMC Infectious Diseases 2019 19:459

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  3. Content type: Research article

    Since 2008, avian influenza surveillance in poultry-related environments has been conducted annually in China. Samples have been collected from environments including live poultry markets, wild bird habitats, ...

    Authors: Ye Zhang, Jie Dong, Hong Bo, Libo Dong, Shumei Zou, Xiyan Li, Yuelong Shu and Dayan Wang

    Citation: BMC Infectious Diseases 2019 19:458

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  4. Content type: Research article

    Human metapneumovirus (HMPV) is a causal agent of acute respiratory infection, especially in primarily children. At the clinical level, HMPV is associated to several diseases including bronchitis, croup, pneum...

    Authors: Mamadou Malado Jallow, Amary Fall, Davy Kiori, Sara Sy, Déborah Goudiaby, Mamadou Aliou Barry, Malick Fall, Mbayame Ndiaye Niang and Ndongo Dia

    Citation: BMC Infectious Diseases 2019 19:457

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  5. Content type: Research article

    Rotavirus gastroenteritis is a major public health problem in Nepal. This study was conducted to obtain information associated with Rotavirus gastroenteritis and to perform genotyping of Rotavirus A.

    Authors: Sony Shrestha, Ocean Thakali, Sunayana Raya, Laxman Shrestha, Keshab Parajuli and Jeevan Bahadhur Sherchand

    Citation: BMC Infectious Diseases 2019 19:456

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  6. Content type: Case report

    Leprosy typically manifests with skin and peripheral nerve involvement. Musculoskeletal complaints are the third most common, and can be the sole presenting manifestation. They range from arthralgia/arthritis ...

    Authors: Miguel Gomes Guerra, Taciana Marta Ferreira Cardoso Videira, Hugo Alexandre Gomes Morais, Telma Cristiana Resse Nunes Santos, Ricardo Jorge Ferreira Taipa, Miguel Araújo Abreu, Romana Carisa Carvalho Vieira, Diogo Miranda Gonçalves Guimarães da Fonseca, Joana Patrícia Abelha Aleixo dos Santos and Sandra Patrícia Abreu Monteiro Pinto

    Citation: BMC Infectious Diseases 2019 19:455

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  7. Content type: Case report

    Mycolicibacterium phlei (M. phlei) is known to be a non-pathogenic nontuberculous mycobacterium (NTM) which rarely causes diseases in humans. A disseminated NTM infection is mostly caused by the Mycobacterium avi...

    Authors: Satomi Tanaka, Yoshihiko Hoshino, Takuro Sakagami, Hanako Fukano, Yohei Matsui and Osamu Hiranuma

    Citation: BMC Infectious Diseases 2019 19:454

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  8. Content type: Research article

    High hemagglutination inhibition (HAI) and neuraminidase inhibition (NAI) titers are generally associated with reduced influenza risk. While repeated influenza vaccination reduces seroresponse, vaccine effecti...

    Authors: Peter B Gilbert, Youyi Fong, Michal Juraska, Lindsay N Carpp, Arnold S Monto, Emily T Martin and Joshua G Petrie

    Citation: BMC Infectious Diseases 2019 19:453

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  9. Content type: Research article

    To investigate the carbapenem resistance mechanisms and clonal relationship of carbapenem-resistant Acinetobacter baumannii (CRAB) strains isolated in the intensive care unit (ICU) of the First Affiliated Hospita...

    Authors: Yongxin Zhao, Kewang Hu, Jisheng Zhang, Yuhang Guo, Xuecai Fan, Yong Wang, Sedzro Divine Mensal and Xiaoli Zhang

    Citation: BMC Infectious Diseases 2019 19:452

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  10. Content type: Research article

    The emergence of leptospirosis-associated severe pulmonary hemorrhagic syndrome (SPHS) with high case fatality has been reported from many countries. Understanding of clinical disease and sequel of SPHS needs ...

    Authors: Nalaka Herath, Wimalasiri Uluwattage, Theshanthi Weliwitiya, Lilani Karunanayake, Sarath Lekamwasam, Neelakanthi Ratnatunga, Panduka Karunanayake, Sugeesha Wickramasinghe, Sanjitha Patabendi, Suranjith Senaviratne and Suneth Agampodi

    Citation: BMC Infectious Diseases 2019 19:451

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  11. Content type: Research article

    Brucellosis is an infectious zoonotic disease and is common especially among pastoral communities in most low and middle-income countries. The aim of this study was to determine sero-prevalence, and risk facto...

    Authors: Nuol Aywel Madut, Moses Ocan, Adrian Muwonge, John Bwalya Muma, George William Nasinyama, Jacques Godfroid, Ambrose Samuel Jubara and Clovice Kankya

    Citation: BMC Infectious Diseases 2019 19:450

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  12. Content type: Research article

    Human pathogens transmitted through environmental pathways are subject to stress and pressures outside of the host. These pressures may cause pathogen pathovars to diverge in their environmental persistence an...

    Authors: Andrew F. Brouwer, Marisa C. Eisenberg, Nancy G. Love and Joseph N.S. Eisenberg

    Citation: BMC Infectious Diseases 2019 19:449

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  13. Content type: Case report

    Pasteurella multocida (P. multocida) forms part of the normal flora of many animals. Although it is a common causative agent of skin and soft tissue infection after an animal bite or scratch, in rare cases it can...

    Authors: Koji Oh, Takafumi Inoue, Toshihiko Saito, Chihiro Nishio and Hiroki Konishi

    Citation: BMC Infectious Diseases 2019 19:448

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  14. Content type: Research article

    Helicobacter pylori (H.pylori) infection is a common medical problem in resource limited areas. The treatment outcome after triple therapy has not been well studied in developing countries and preliminary data su...

    Authors: Hyasinta Jaka, Andreas Mueller, Christa Kasang and Stephen E. Mshana

    Citation: BMC Infectious Diseases 2019 19:447

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  15. Content type: Research article

    Detailed knowledge about viral respiratory disease transmission dynamics within healthcare institutions is essential for effective infection control policy and practice. In the quest to study viral transmissio...

    Authors: Hila Schwarz, Jürg Böni, Roger D. Kouyos, Teja Turk, Edouard Battegay, Malcolm Kohler, Rouven Müller, Heidi Petry, Hugo Sax, Rainer Weber, Allison McGeer, Alexandra Trkola and Stefan P. Kuster

    Citation: BMC Infectious Diseases 2019 19:446

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  16. Content type: Research article

    Candidaemia is associated with high mortality. Variables associated with mortality have been published previously, but not developed into a risk predictive model for mortality. We sought to describe the curren...

    Authors: C. Keighley, S. C-A. Chen, D. Marriott, A. Pope, B. Chapman, K. Kennedy, N. Bak, N. Underwood, H. L. Wilson, K. McDonald, J. Darvall, C. Halliday, S. Kidd, Q. Nguyen, K. Hajkowicz, T. C. Sorrell…

    Citation: BMC Infectious Diseases 2019 19:445

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  17. Content type: Research article

    Visceral Leishmaniasis (VL) is caused by a protozoan parasite Leishmania donovani that is transmitted to humans by an infected female sandfly, Phlebotomus argentipes. VL is common in the Indian sub-continent incl...

    Authors: Mitesh Shrestha, Medha Khatri-Chhetri, Ram Chandra Poudel, Jyoti Maharjan, Shyam Prakash Dumre, Krishna Das Manandhar, Basu Dev Pandey, Sher Bahadur Pun and Kishor Pandey

    Citation: BMC Infectious Diseases 2019 19:444

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  18. Content type: Research article

    Lymphatic Filariasis (LF) is a vector-borne neglected tropical disease caused by the filarial nematode parasites that can lead to the disfiguring swelling of the limbs (lymphedema or elephantiasis for late sta...

    Authors: Alexander Kwarteng, Yarhands Dissou Arthur, John Kanyiri Yamba, Augustina A. Sylverken, Priscilla Kini, Samuel Terkper Ahuno and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2019 19:442

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  19. Content type: Research article

    São José do Rio Preto is one of the cities of the state of São Paulo, Brazil, that is hyperendemic for dengue, with the presence of the four dengue serotypes.

    Authors: Francisco Chiaravalloti-Neto, Rafael Alves da Silva, Nathalia Zini, Gislaine Celestino Dutra da Silva, Natal Santos da Silva, Maisa Carla Pereira Parra, Margareth Regina Dibo, Cassia Fernanda Estofolete, Eliane Aparecida Fávaro, Karina Rocha Dutra, Manlio Tasso Oliveira Mota, Georgia Freitas Guimarães, Ana Carolina Bernardes Terzian, Marta Blangiardo and Mauricio Lacerda Nogueira

    Citation: BMC Infectious Diseases 2019 19:441

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  20. Content type: Research article

    Hepatitis B virus (HBV) infection is a major public health burden in China although it has steadily declined over the last two decades. A valid updated prevalence of HBV infection in China relies on a large sa...

    Authors: Jing Meng, Hongqin Xu, Dongming Sui, Jing Jiang, Jie Li, Yanhang Gao and Junqi Niu

    Citation: BMC Infectious Diseases 2019 19:440

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  21. Content type: Research article

    Brucellosis has extensive clinical spectrum, clinicians have insufficient understanding of the disease, and the misdiagnosis rate is still high. By collecting and analyzing the clinical characteristics of pati...

    Authors: Wenhui Jiang, Jiwang Chen, Qian Li, Lisheng Jiang, Yanxin Huang, Yinghua Lan and Yongguo Li

    Citation: BMC Infectious Diseases 2019 19:439

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  22. Content type: Research article

    Gram-positive organisms are a leading cause of infection in cardiovascular surgery. Furthermore, these patients have a high risk of developing postoperative renal failure in intensive care unit (ICU). Some ant...

    Authors: Philippe Gaudard, Marine Saour, David Morquin, Hélène David, Jacob Eliet, Maxime Villiet, Jean-Pierre Daures and Pascal Colson

    Citation: BMC Infectious Diseases 2019 19:438

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  23. Content type: Research article

    Staphylococcus aureus (S. aureus) is a common cause of bacteremia, which leads to significant morbidity and mortality. We investigated the relationship between time to positivity (TTP) and clinical outcomes in ch...

    Authors: Yuanyuan Li, Qinyuan Li, Guangli Zhang, Huan Ma, Yi Wu, Qian Yi, Lili Jiang, Jiao Wan, Fengtao Suo and Zhengxiu Luo

    Citation: BMC Infectious Diseases 2019 19:437

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  24. Content type: Research article

    Information on non-tuberculosis mycobacterial (NTM) diseases remains limited in Singapore and other Southeast Asian countries. This study aimed to delineate epidemiological and clinical features of pulmonary N...

    Authors: Zoe Xiaozhu Zhang, Benjamin Pei Zhi Cherng, Li-Hwei Sng and Yen Ee Tan

    Citation: BMC Infectious Diseases 2019 19:436

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  25. Content type: Research article

    Over the past decades there have been outbreaks of mumps in many countries, even in populations that were vaccinated. Some studies suggest that the incidence of mumps is related to meteorological changes, but ...

    Authors: Yu Hao, Ran-ran Wang, Ling Han, Hong Wang, Xuan Zhang, Qiao-ling Tang, Long Yan and Juan He

    Citation: BMC Infectious Diseases 2019 19:435

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  26. Content type: Research article

    Four species within Anaplasma genus are emerging zoonotic pathogens, which are transmitted by ticks and generate veterinary and public health concerns. Here, we performed a molecular survey of Anaplasma in Ankang...

    Authors: Wen-Ping Guo, Bing Zhang, Yi-Han Wang, Gang Xu, Xiaoquan Wang, Xuebing Ni and En-Min Zhou

    Citation: BMC Infectious Diseases 2019 19:434

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  27. Content type: Research article

    Natural killer (NK) cells are part of the innate immune system and provide surveillance against viruses and cancers. The ability of NK cells to kill virus-infected cells depends on the balance between the effects...

    Authors: Gabriel Andrade Nonato Queiroz, Rita Elizabeth Moreira Mascarenhas, Vincent Vieillard, Raphaela Lisboa Andrade, Bernardo Galvão-Castro and Maria Fernanda Rios Grassi

    Citation: BMC Infectious Diseases 2019 19:433

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  28. Content type: Research article

    The HIV epidemic remains a concern on the global health agenda, despite progress made in reducing incidence. Investigation of trends among young people is important for monitoring HIV incidence and informing p...

    Authors: Chola Nakazwe, Charles Michelo, Ingvild F. Sandøy and Knut Fylkesnes

    Citation: BMC Infectious Diseases 2019 19:432

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  29. Content type: Research article

    Onchocerciasis is a neglected tropical disease which is still of immense major public health concern in several areas of Africa and the Americas. The disease manifests either as ocular or as dermal onchocercia...

    Authors: Kenneth Bentum Otabil, Samuel Fosu Gyasi, Esi Awuah, Daniels Obeng-Ofori, Robert Junior Atta-Nyarko, Dominic Andoh, Beatrice Conduah, Lawrence Agbenyikey, Philip Aseidu, Comfort Blessing Ankrah, Abdul Razak Nuhu and H. D. F. H. Schallig

    Citation: BMC Infectious Diseases 2019 19:431

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  30. Content type: Research article

    Despite the undeniable significance of blood transfusion in saving a millions life in emergencies and medical treatment, the quality of blood faced challenges from transfusion-transmitted infections (TTIs) suc...

    Authors: Markos Negash, Moges Ayalew, Demeke Geremew and Meseret Workineh

    Citation: BMC Infectious Diseases 2019 19:430

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  31. Content type: Research article

    Several randomized controlled trials (RCTs) evaluated the role of Chlorhexidine-impregnated dressing for prophylaxis of central venous catheter (CVC) related complications, but the results remained inconsisten...

    Authors: Li Wei, Yan Li, Xiaoyan Li, Lanzheng Bian, Zunjia Wen and Mei Li

    Citation: BMC Infectious Diseases 2019 19:429

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  32. Content type: Research article

    Diagnosing extrapulmonary tuberculosis (EPTB) is challenging and many patients are initiated on empirical anti-TB treatment without a laboratory confirmed diagnosis. Monitoring treatment response is thus impor...

    Authors: Melissa Davidsen Jørstad, Anne Ma Dyrhol-Riise, Jörg Aßmus, Msafiri Marijani, Lisbet Sviland and Tehmina Mustafa

    Citation: BMC Infectious Diseases 2019 19:426

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  33. Content type: Research article

    Understanding the underlying epidemiology that shapes Neisseria gonorrhoeae (GC), and Chlamydia trachomatis (CT) infections can contribute to data driven policies directed towards curbing the proliferation of the...

    Authors: Helena Dela, Naiki Attram, Eric Behene, Selassie Kumordjie, Kwasi Kennedy Addo, Edward Owusu Nyarko, Nicholas N. A. Kyei, John Nii Ayite Carroll, Cynthia Kwakye, Christopher Anthony Duplessis, Nehkonti Adams, Eric Garges and Andrew Gordon Letizia

    Citation: BMC Infectious Diseases 2019 19:425

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  34. Content type: Research article

    The study was conducted in a remote sputum sample collection sites and GeneXpert® MTB/RIF testing centers to detect Mycobacterium tuberculosis in Malawi. The main purpose of the study was to evaluate whether sput...

    Authors: Wondwossen A. Alemayehu, S. Neri, S. Dalebout, R. Nalikungwi, A. Trusov, E. Ahmed, A. Dimba, A. Weirich, P. S. Curry and C. D. Kelly-Cirino

    Citation: BMC Infectious Diseases 2019 19:424

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  35. Content type: Research article

    Determining the etiology of pneumonia is essential to guide public health interventions. Diagnostic test results, including from polymerase chain reaction (PCR) assays of upper respiratory tract specimens, hav...

    Authors: Ying Lu, Lawrence Joseph, Patrick Bélisle, Pongpun Sawatwong, Anchalee Jatapai, Toni Whistler, Somsak Thamthitiwat, Wantana Paveenkittiporn, Supphacoke Khemla, Chris A. Van Beneden, Henry C. Baggett and Christopher J. Gregory

    Citation: BMC Infectious Diseases 2019 19:423

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  36. Content type: Research article

    Cholera increases the risk of harmful effects on foetuses. We prospectively followed pregnant women unaware of their pregnancy status who received a study agent in a clinical trial evaluating the association b...

    Authors: Ashraful Islam Khan, Mohammad Ali, Julia Lynch, Alamgir Kabir, Jean-Louis Excler, Md. Arifuzzaman Khan, Md. Taufiqul Islam, Afroza Akter, Fahima Chowdhury, Amit Saha, Iqbal Ansary Khan, Sachin N. Desai, Deok Ryun Kim, Nirod Chandra Saha, Ajit P. Singh, John D. Clemens…

    Citation: BMC Infectious Diseases 2019 19:422

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  37. Content type: Research article

    Urinary tract infection is an infection affecting infants and children. The aim of this study was to determine the etiology of urinary tract infection along with their antimicrobial resistance.

    Authors: Rabina Ganesh, Dhiraj Shrestha, Balkrishna Bhattachan and Ganesh Rai

    Citation: BMC Infectious Diseases 2019 19:420

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  38. Content type: Research article

    Human immunodeficiency virus (HIV) infected children represent a very vulnerable population for anti-retroviral therapy (ART) drug resistance. As a global target, 90% of patients receiving ART should have HIV-...

    Authors: Melashu Balew Shiferaw, Demeke Endalamaw, Mulat Hussien, Manamnot Agegne, Desalegn Amare, Fikirte Estifanos and Dinbere Temesgen

    Citation: BMC Infectious Diseases 2019 19:419

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  39. Content type: Research article

    The global expansion of dengue (DENV), chikungunya (CHIKV), and Zika viruses (ZIKV) is having a serious impact on public health. Because these arboviruses are transmitted by the same mosquito species and co-ci...

    Authors: Lyudmyla G. Glushakova, Barry W. Alto, Myong-Sang Kim, Daniel Hutter, Andrea Bradley, Kevin M. Bradley, Nathan D. Burkett-Cadena and Steven A. Benner

    Citation: BMC Infectious Diseases 2019 19:418

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  40. Content type: Research article

    In Ethiopia, morbidity and mortality due to diarrhea is significantly high. Most importantly, burden of diarrhea is disproportionately high among under-five children. Therefore, the objective of this study was...

    Authors: Amare Belachew Dagnew, Tilahun Tewabe, Yihun Miskir, Tariku Eshetu, Wosin Kefelegn, Kidanu Zerihun, Mekonnen Urgessa and Tiruha Teka

    Citation: BMC Infectious Diseases 2019 19:417

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  41. Content type: Research article

    Chlorhexidine gluconate (CHG) bathing of hospitalized patients may have benefit in reducing hospital-acquired bloodstream infections (HABSIs). However, the magnitude of effect, implementation fidelity, and pat...

    Authors: Jackson S. Musuuza, Pramod K. Guru, John C. O’Horo, Connie M. Bongiorno, Marc A. Korobkin, Ronald E. Gangnon and Nasia Safdar

    Citation: BMC Infectious Diseases 2019 19:416

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  42. Content type: Research article

    Establishing epidemiological models and conducting predictions seems to be useful for the prevention and control of human brucellosis. Autoregressive integrated moving average (ARIMA) models can capture the lo...

    Authors: Wei Wu, Shu-Yi An, Peng Guan, De-Sheng Huang and Bao-Sen Zhou

    Citation: BMC Infectious Diseases 2019 19:414

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  43. Content type: Research article

    Malaria continues to be a public health problem and important cause of morbidity and mortality in Ethiopia. Due to continuous interventions to combat malaria in endemic regions, a decline in malaria related de...

    Authors: Teha Shumbej, Abdulewhab Jemal, Abdulsemed Worku, Fitsum Bekele and Habtamu Weldesenbet

    Citation: BMC Infectious Diseases 2019 19:413

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  44. Content type: Research article

    Colorectal surgery is associated with high rates of surgical site infection (SSI). We investigated SSI in radical resection of colon or rectal carcinoma and its epidemiological distribution in 26 hospitals in ...

    Authors: Mingmei Du, Bowei Liu, Meng Li, Jingui Cao, Ding Liu, Zhigang Wang, Qiongshu Wang, Pengyun Xiao, Xinling Zhang, Yanxin Gao, Hua Zeng, Jing Yang, Xiaoli Xu, Yi Huang, Qun Zhang, Bo Zhang…

    Citation: BMC Infectious Diseases 2019 19:411

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  45. Content type: Research article

    Consumption of unwashed, raw or unhygienically prepared fruits and vegetables act as potential source for the spread of various parasitic diseases. Moreover, the level of contamination and species of contamina...

    Authors: Getaneh Alemu, Mohammedaman Mama, Direslgne Misker and Desta Haftu

    Citation: BMC Infectious Diseases 2019 19:410

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