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  1. To quantitatively assess the impact of the onset-to-diagnosis interval (ODI) on severity and death for coronavirus disease 2019 (COVID-19) patients.

    Authors: Qing-Bin Lu, Tian-Le Che, Li-Ping Wang, An-Ran Zhang, Xiang Ren, Tao Wang, Meng-Jie Geng, Yi-Fei Wang, Meng-Yang Liu, Hai-Yang Zhang, Li-Qun Fang, Wei Liu and Zhong-Jie Li
    Citation: BMC Infectious Diseases 2022 22:674
  2. Factors that lead to successful SARS-CoV-2 transmission are still not well described. We investigated the association between a case’s viral load and the risk of transmission to contacts in the context of othe...

    Authors: Darlene Bhavnani, Emily R. James, Kaitlyn E. Johnson, Sylvie Beaudenon-Huibregtse, Patrick Chang, Paul J. Rathouz, Minda Weldon, Andreas Matouschek and Amy E. Young
    Citation: BMC Infectious Diseases 2022 22:672
  3. Hand, foot, and mouth disease (HFMD) is a common child infectious disease caused by more than 20 enterovirus (EV) serotypes. In recent years, enterovirus A71 (EV-A71) has been replaced by Coxsackievirus A6 (CV-A6...

    Authors: Wei Guo, Danhan Xu, Shanri Cong, Zengqing Du, Li Li, Ming Zhang, Changzeng Feng, Guohong Bao, Hao Sun, Zhaoqing Yang and Shaohui Ma
    Citation: BMC Infectious Diseases 2022 22:671
  4. Vibrio vulnificus infections develop rapidly and are associated with a high mortality rate. The rates of diagnosis and treatment are directly associated with mortality.

    Authors: Weihua Di, Jing Cui, Hui Yu, Xiao Cui, Huanlan Sa, Zhong Fu, Bingjin Fu, Guofeng Guan, Rui Du, Cuijie Shao and Yong Gao
    Citation: BMC Infectious Diseases 2022 22:670
  5. At present, no single efficacious therapeutic exists for acute COVID-19 management and a multimodal approach may be necessary. 2-deoxy-d-glucose (2-DG) is a metabolic inhibitor that has been shown to limit multip...

    Authors: Anant Narayan Bhatt, Srinivas Shenoy, Sagar Munjal, Vijayakumar Chinnadurai, Apurva Agarwal, A. Vinoth Kumar, A. Shanavas, Ratnesh Kanwar and Sudhir Chandna
    Citation: BMC Infectious Diseases 2022 22:669
  6. Uganda accounts for 5% of all malaria cases and deaths reported globally and, in endemic countries, pregnancy is a risk factor for both acquisition of P. falciparum infection and development of severe malaria. In...

    Authors: Francesco Vladimiro Segala, Francesco Di Gennaro, Jerry Ictho, Mariangela L’Episcopia, Emmanuel Onapa, Claudia Marotta, Elda De Vita, James Amone, Valentina Iacobelli, Joseph Ogwang, Giovanni Dall’Oglio, Benedict Ngole, Rita Murri, Lameck Olal, Massimo Fantoni, Samuel Okori…
    Citation: BMC Infectious Diseases 2022 22:668
  7. A prospective interventional study comparing outcomes in critically ill patients receiving intermittent infusion (II) or continuous infusion (CI) of vancomycin during continuous venovenous hemofiltration (CVVH...

    Authors: Jinhui Xu, Lufen Duan, Jiahui Li, Fang Chen, Xiaowen Xu, Jian Lu, Zhiwei Zhuang, Yifei Cao, Yunlong Yuan, Xin Liu, Jiantong Sun, Qin Zhou, Lu Shi and Lian Tang
    Citation: BMC Infectious Diseases 2022 22:667
  8. Chronic rhinosinusitis (CRS) affects the quality of life of many people worldwide and can cause comorbidities. Our previous research proved that Sjogren’s syndrome (SS) is a predisposing factor for CRS, with a...

    Authors: Pei-Rung Yang, Wei-Tai Shih, Yao-Hsu Yang, Chia-Yen Liu, Ming-Shao Tsai, Yao-Te Tsai, Cheng-Ming Hsu, Ching-Yuan Wu, Pey-Jium Chang and Geng-He Chang
    Citation: BMC Infectious Diseases 2022 22:666
  9. Patients with adult-onset immunodeficiency syndrome due to anti-interferon-γ autoantibodies (AIGAs) are susceptible to disseminated Mycobacterium avium complex (MAC) infections. M. chimaera, a newly identified MA...

    Authors: Yi-Fu Lin, Tai-Fen Lee, Un-In Wu, Chun-Fu Huang, Aristine Cheng, Kuan-Yin Lin and Chien-Ching Hung
    Citation: BMC Infectious Diseases 2022 22:665
  10. Numerous scoring tools have been developed for assessing the probability of SARS-COV-2 test positivity, though few being suitable or adapted for outpatient triage of health care workers.

    Authors: Hannah Tuulikki Hohl, Guenter Froeschl, Michael Hoelscher and Christian Heumann
    Citation: BMC Infectious Diseases 2022 22:664
  11. China has experienced a continuous decreasing trend in the incidence of hepatitis A in recent years. Temporal trend analyses are helpful in exploring the reasons for the changing trend. Thus, this study aims t...

    Authors: Yuan-Sheng Li, Bei-Bei Zhang, Xi Zhang, Song Fan, Li-Ping Fei, Chao Yang, Ning-Jun Ren, Xiang Li, Ya-Mei Luo and Jun-Hui Zhang
    Citation: BMC Infectious Diseases 2022 22:663
  12. We aimed to explore the prognostic utilities of C-reactive protein (CRP), procalcitonin (PCT), neutrophil CD64 (nCD64) index, in combination or alone, in septic patients.

    Authors: Na Huang, Jing Chen, Yu Wei, Yongrui Liu, Kang Yuan, Jingli Chen, Mingfeng He and Nan Liu
    Citation: BMC Infectious Diseases 2022 22:662
  13. Regional labour markets and their properties are named as potential reasons for regional variations in levels of SARS-CoV-2 infections rates, but empirical evidence is missing.

    Authors: Morten Wahrendorf, Marvin Reuter, Jens Hoebel, Benjamin Wachtler, Annika Höhmann and Nico Dragano
    Citation: BMC Infectious Diseases 2022 22:661
  14. Increased intensity of pyrethroid resistance is threatening the effectiveness of insecticide-based interventions to control malaria in Africa. Assessing the extent of this aggravation and its impact on the eff...

    Authors: Benjamin D. Menze, Magellan Tchouakui, Leon M. J. Mugenzi, Williams Tchapga, Micareme Tchoupo, Murielle J. Wondji, Martin Chiumia, Themba Mzilahowa and Charles S. Wondji
    Citation: BMC Infectious Diseases 2022 22:660
  15. The COVID-19 pandemic has affected all people across the globe. Regional and community differences in timing and severity of surges throughout the pandemic can provide insight into risk factors for worse outco...

    Authors: Suneha S. Sundaram, Stephanie Melquist, Pankush Kalgotra, Sachin Srinivasan, Sravanthi Parasa, Madhav Desai and Prateek Sharma
    Citation: BMC Infectious Diseases 2022 22:659
  16. Sarcoptes scabiei is one of the most impactful mammalian parasites. There has been much research on immunological and clinical pathological changes associated with S. scabiei parasitism across a range of host spe...

    Authors: Christina Næsborg-Nielsen, Vicky Wilkinson, Natalia Mejia-Pacheco and Scott Carver
    Citation: BMC Infectious Diseases 2022 22:658
  17. Immunosuppressive chemotherapy increase the risk of vaccine-preventable infectious diseases in children; nevertheless, chemotherapy may result in delay or miss updated immunization schedules. The predictable a...

    Authors: Babak Abdolkarimi, Ali Amanati, Hossein Molavi Vardanjani, Safura‏ ‏Jamshidi and Seid Amir Pasha Tabaeian
    Citation: BMC Infectious Diseases 2022 22:657
  18. Multiple waves of the COVID-19 epidemic have hit most countries by the end of 2021. Most of those waves are caused by emergence and importation of new variants. To prevent importation of new variants, combinat...

    Authors: Keisuke Ejima, Kwang Su Kim, Ana I. Bento, Shoya Iwanami, Yasuhisa Fujita, Kazuyuki Aihara, Kenji Shibuya and Shingo Iwami
    Citation: BMC Infectious Diseases 2022 22:656
  19. Although previous epidemiological studies have examined the potential risk factors that increase the likelihood of acquiring Helicobacter pylori infections, most of these analyses have utilized conventional stati...

    Authors: Van Tran, Tazmilur Saad, Mehret Tesfaye, Sosina Walelign, Moges Wordofa, Dessie Abera, Kassu Desta, Aster Tsegaye, Ahmet Ay and Bineyam Taye
    Citation: BMC Infectious Diseases 2022 22:655
  20. The rapid course of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic calls for fast implementation of clinical trials to assess the effects of new treatment and prophylactic interventi...

    Authors: Katharina Kusejko, Frédérique Chammartin, Daniel Smith, Marc Odermatt, Julian Schuhmacher, Michael Koller, Huldrych F. Günthard, Matthias Briel, Heiner C. Bucher and Benjamin Speich
    Citation: BMC Infectious Diseases 2022 22:654
  21. While national malaria incidence has been declining in Myanmar, some subregions within the nation continue to have high burdens of malaria morbidity and mortality. This study assessed the malaria situation in ...

    Authors: Pyae Linn Aung, Myat Thu Soe, Thit Lwin Oo, Kyaw Thu Aung, Kyaw Kyaw Lin, Aung Thi, Lynette Menezes, Daniel M. Parker, Liwang Cui and Myat Phone Kyaw
    Citation: BMC Infectious Diseases 2022 22:653

    The Correction to this article has been published in BMC Infectious Diseases 2022 22:708

  22. Staphylococcus aureus causes many human infections, including wound infections, and its pathogenicity is mainly influenced by several virulence factors.

    Authors: Asia Helmi Rasmi, Eman Farouk Ahmed, Abdou Mohammed Abdullah Darwish and Gamal Fadl Mahmoud Gad
    Citation: BMC Infectious Diseases 2022 22:652
  23. At present, skeletal tuberculosis (TB) diagnosis is mostly by histopathology, but the positivity rate is low. There is a need to develop new methods for the molecular identification of this disorder. Therefore...

    Authors: Gang He, Chun-yu Chen, Xin Zhang, Pei-pei Ding, Chang-zheng Hu, Xiu-fang Huang, Xian Zhang, Xu Gong, Pei-lin Zhen and Liang Zhang
    Citation: BMC Infectious Diseases 2022 22:651
  24. Direct-acting antivirals (DAAs) are highly effective in achieving sustained virologic response among those with chronic hepatitis C virus (HCV) infection. Quality of life (QOL) benefits for an HCV-infected pop...

    Authors: M. Benade, S. Rosen, S. Antoniak, C. Chasela, Y. Stopolianska, T. Barnard, M. M. Gandhi, I. Ivanchuk, V. Tretiakov, J. Dible, T. Minior, K. W. Chew, C. van der Horst, Z. Tsenilova and I. Sanne
    Citation: BMC Infectious Diseases 2022 22:650
  25. Since the emergence of SARS-CoV-2, evolutionary pressure has driven large increases in the transmissibility of the virus. However, with increasing levels of immunity through vaccination and natural infection t...

    Authors: Oliver Eales, Andrew J. Page, Leonardo de Oliveira Martins, Haowei Wang, Barbara Bodinier, David Haw, Jakob Jonnerby, Christina Atchison, Deborah Ashby, Wendy Barclay, Graham Taylor, Graham Cooke, Helen Ward, Ara Darzi, Steven Riley, Marc Chadeau-Hyam…
    Citation: BMC Infectious Diseases 2022 22:647
  26. It is vital to distinguish between inflammatory and malignant lymphadenopathy in human immunodeficiency virus (HIV) infected individuals. The purpose of our study was to differentiate the variations in the cli...

    Authors: Donghe Chen, Yunqi Zhu, Yunbo Chen, Danhua Zhu, Zhengfeng Liu, Tiancheng Li, Yinuo Liu, Kui Zhao, Xinhui Su and Lanjuan Li
    Citation: BMC Infectious Diseases 2022 22:646
  27. Monoclonal antibodies (mAb) prevent COVID-19 progression when administered early. We compared mAb treatment outcomes among vaccinated and unvaccinated patients during Delta wave and assessed the feasibility of...

    Authors: Yi Guo, Kelsie Cowman, Mei Chang, Hongkai Bao, Austin Golia, Terrence Mcsweeney, Linda Bard, Roxanne Simpson, Erin Andrews, Liise-anne Pirofski and Priya Nori
    Citation: BMC Infectious Diseases 2022 22:645
  28. The ability of SARS-CoV-2 to remain in asymptomatic individuals facilitates its dissemination and makes its control difficult. Objective. To establish a cohort of asymptomatic individuals, change to the sympto...

    Authors: Caty Martínez, Héctor Serrano-Coll, Álvaro Faccini, Verónica Contreras, Ketty Galeano, Yesica Botero, Yonairo Herrera, Alejandra Garcia, Evelin Garay, Ricardo Rivero, Héctor Contreras, Yesica López, Camilo Guzmán, Jorge Miranda, Germán Arrieta and Salim Mattar
    Citation: BMC Infectious Diseases 2022 22:644
  29. Serological methods provide useful metrics to estimate age-specific period prevalence in settings of low malaria transmission; however, evidence on the use of seropositivity as an endpoint remains scarce in st...

    Authors: T. Druetz, L. van den Hoogen, G. Stresman, V. Joseph, K. E. S. Hamre, C. Fayette, F. Monestime, J. Presume, I. Romilus, G. Mondélus, T. Elismé, S. Cooper, D. Impoinvil, R. A. Ashton, E. Rogier, A. Existe…
    Citation: BMC Infectious Diseases 2022 22:643
  30. Patient retention in care and sustained viral load suppression are a cornerstone to improved health and quality of life, among people living with HIV. However, challenges of retention on ART remain among femal...

    Authors: Lydia Atuhaire, Constance S. Shumba, Lovemore Mapahla and Peter S. Nyasulu
    Citation: BMC Infectious Diseases 2022 22:642
  31. The COVID-19 pandemic has driven public health intervention strategies, including keeping social distance, wearing masks in crowded places, and having good health habits, to prevent the transmission of the nov...

    Authors: Ziwei Wu, Ziyi Chen, Siyu Long, Aiping Wu and Hongsheng Wang
    Citation: BMC Infectious Diseases 2022 22:641
  32. We report the first case of COVID-19 associated acute necrotizing encephalopathy (ANE) without pulmonary disease in a patient with an extremely high interleukin-6 (IL-6) level and Ran Binding Protein 2 (RANBP2) m...

    Authors: Thanakit Pongpitakmetha, Pasin Hemachudha, Wanakorn Rattanawong, Poosanu Thanapornsangsuth, Anand Viswanathan and Thiravat Hemachudha
    Citation: BMC Infectious Diseases 2022 22:640
  33. The role of ivermectin in the treatment of COVID-19 is still under debate, yet the drug has been widely used in some parts of the world, as shown by impressive market data. The available body of evidence may h...

    Authors: Milena Soriano Marcolino, Karina Cardoso Meira, Nathalia Sernizon Guimarães, Paula Perdigão Motta, Victor Schulthais Chagas, Silvana Márcia Bruschi Kelles, Laura Caetano de Sá, Reginaldo Aparecido Valacio and Patrícia Klarmann Ziegelmann
    Citation: BMC Infectious Diseases 2022 22:639
  34. Recurrence continues to place significant burden on patients and tuberculosis programmes worldwide, and previous studies have rarely provided analysis in negative recurrence cases. We characterized the epidemi...

    Authors: Hui Jiang, Jinfeng Yin, Fangchao Liu, Yuxia Yao, Chao Cai, Jiying Xu, Lijun Zheng, Chendi Zhu, Junnan Jia, Xu Gao, Wangli Xu, Weimin Li and Guolong Zhang
    Citation: BMC Infectious Diseases 2022 22:638
  35. Airspace disease as seen on chest X-rays is an important point in triage for patients initially presenting to the emergency department with suspected COVID-19 infection. The purpose of this study is to evaluat...

    Authors: Jordan H. Chamberlin, Gilberto Aquino, Sophia Nance, Andrew Wortham, Nathan Leaphart, Namrata Paladugu, Sean Brady, Henry Baird, Matthew Fiegel, Logan Fitzpatrick, Madison Kocher, Florin Ghesu, Awais Mansoor, Philipp Hoelzer, Mathis Zimmermann, W. Ennis James…
    Citation: BMC Infectious Diseases 2022 22:637
  36. The purpose of the current study was to evaluate the association between C-reactive protein-to-platelet ratio (CPR), neutrophil-to-lymphocyte*platelet ratio (NLPR) and fibrinogen-to-platelet ratio (FPR) and th...

    Authors: Shixiao Li, Sufei Yu, Jiajia Qin, Minfei Peng, Jiao Qian and Peng Zhou
    Citation: BMC Infectious Diseases 2022 22:636
  37. Nocardia cyriacigeorgica was first described in 2001. It is an emerging pathogen that mainly affects immunocompromised patients. A brain abscess caused by N. cyriacigeorgica has been reported only in immunocom...

    Authors: Segev Gabay, Michal Yakubovsky, Ronen Ben-Ami and Rachel Grossman
    Citation: BMC Infectious Diseases 2022 22:635
  38. Tenofovir disoproxil fumarate (TDF) in combination with other antiretroviral (ARV) drugs has been in clinical use for HIV treatment since its approval in 2001. Although the effectiveness of TDF in preventing p...

    Authors: Kristin Baltrusaitis, Bonus Makanani, Camlin Tierney, Mary Glenn Fowler, Dhayendre Moodley, Gerhard Theron, Lynette H. Nyakudya, Musunga Tomu, Lee Fairlie, Kathleen George, Barbara Heckman, Kevin Knowles, Renee Browning, George K. Siberry, Taha E. Taha and Lynda Stranix-Chibanda
    Citation: BMC Infectious Diseases 2022 22:634
  39. The outbreak of SARS-CoV-2 at the end of 2019 sounded the alarm for early inspection on acute respiratory infection (ARI). However, diagnosis pathway of ARI has still not reached a consensus and its impact on ...

    Authors: Guanmin Yuan, Hongyu Wang, Yuanhan Zhao, Enqiang Mao, Mengjiao Li, Ruilan Wang, Fangqing Zhou, Shanshan Jin, Ziqiang Zhang, Ke Xu, Jinfu Xu, Shuo Liang, Xiang Li, Lijing Jiang, Lu Zhang, Jieyu Song…
    Citation: BMC Infectious Diseases 2022 22:632
  40. Staphylococcus aureus bacteremia (SAB) is one of the most frequent bloodstream infections. High mortality of SAB can be significantly reduced by regular infectious disease (ID) consultations and appropriate clini...

    Authors: Simona Arientová, Zdeněk Jícha, Ondřej Beran and Michal Holub
    Citation: BMC Infectious Diseases 2022 22:631
  41. Sepsis is still a major public health concern and a medical emergency due to its high morbidity and mortality. Accurate and timely etiology diagnosis is crucial for sepsis management. As an emerging rapid and ...

    Authors: Yuanhan Zhao, Ke Lin, Haocheng Zhang, Guanmin Yuan, Yanliang Zhang, Jingye Pan, Liang Hong, Yan Huang, Ying Ye, Lisu Huang, Xiaohua Chen, Jun Liu, Xiang Li, Xiaoju He, Qiaoyan Yue, Hong Zhang…
    Citation: BMC Infectious Diseases 2022 22:630
  42. Sepsis still threatens the lives of more than 300 million patients annually and elderly patients with sepsis usually have a more complicated condition and a worse prognosis. Existing studies have shown that bo...

    Authors: Zichen Wang, Luming Zhang, Shaojin Li, Fengshuo Xu, Didi Han, Hao Wang, Tao Huang, Haiyan Yin and Jun Lyu
    Citation: BMC Infectious Diseases 2022 22:629
  43. Mycobacterium africanum is a member of the Mycobacterium tuberculosis complex (MTBC) and is endemic in West Africa, where it causes up to half of all cases of pulmonary tuberculosis. Here, we report the first is...

    Authors: Paula Mascarell, Alba de la Rica, Sergio Padilla, Montserrat Ruiz-García, José López-Escudero, Javier García-Abellán, Ángela Botella, Mar Masiá and Félix Gutiérrez
    Citation: BMC Infectious Diseases 2022 22:628
  44. Meningitis is considered a life-threatening infection with high mortality all over the world. Hemophilus influenzae (H. influenzae) and Streptococcus pneumoniae (S. pneumoniae) are regarded as the two most common...

    Authors: Sedigheh Rafiei Tabatabaei, Ahmadreza Shamshiri, Leila Azimi, Ali Nazari-Alam, Abdollah Karimi, Seyed Alireza Mirjavadi and Marjan Tariverdi
    Citation: BMC Infectious Diseases 2022 22:625
  45. Globally, hearing loss is the second leading cause of disability, affecting approximately 18.7% of the world’s population. However, the burden of hearing loss is unequally distributed, with the majority of aff...

    Authors: Samuel C. Ficenec, Donald S. Grant, Ibrahim Sumah, Foday Alhasan, Mohamed S. Yillah, Jenneh Brima, Edwin Konuwa, Michael A. Gbakie, Fatima K. Kamara, Nell G. Bond, Emily J. Engel, Jeffrey G. Shaffer, William A. Fischer, David A. Wohl, Susan D. Emmett and John S. Schieffelin
    Citation: BMC Infectious Diseases 2022 22:624

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