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  1. Studies have shown that more than 50% of the antibiotics used in hospitals are unnecessary or inappropriate and, that antimicrobial resistance may cost up to 20 billion USD in excess medical costs each year. O...

    Authors: Christian José Pallares, Jessica Porras, Elsa De La Cadena, Juan Carlos García-Betancur, Natalia Restrepo-Arbeláez, Sara María Cobo Viveros, Wanda Cornistein, Paulo Castañeda-Méndez, Luis Cuellar, Diogo Boldim-Ferreira, Jorge Chaverri-Murillo, Jaime A. Labarca and María Virginia Villegas
    Citation: BMC Infectious Diseases 2023 23:463
    Content type: Research Published on:

  2. B7-H3 is an important immune checkpoint molecule that plays a negative role in immune regulation. This study was aimed to explore B7-H3 expression in HIV-infected patients and its clinical significance.

    Authors: Jun-Chi Xu, Hui Chen, Ping Xu, Xin-Ran You, Geng-chao Zhu and Fei Gao
    Citation: BMC Infectious Diseases 2023 23:462
    Content type: Research Published on:

  4. The success of mass drug administration (MDA) campaigns to control and eliminate neglected tropical diseases (NTDs) in Ghana depends, to a large extent, on the essential role community drug distributors (CDDs)...

    Authors: Akua Obeng Forson, Raphael Baffour Awuah, Abdul Rahim Mohammed, Christopher Mfum Owusu-Asenso, Sefa Bonsu Atakora, Gabriel Akosah-Brempong, Anisa Abdulai, Isaac Kwame Sraku, Shittu B. Dhikrullahi, Simon K. Attah and Yaw Asare Afrane
    Citation: BMC Infectious Diseases 2023 23:460
    Content type: Research Published on:

  6. The rate of community antibiotic use is high in Aotearoa New Zealand (NZ) when compared to other nations, and in NZ, as in most other nations, antibiotics are very commonly prescribed for self-limiting upper r...

    Authors: S Thaggard, S Reid, AHY Chan, C White, L Fraser, BA Arroll, E Best, R Whittaker, S Wells, MG Thomas and SR Ritchie
    Citation: BMC Infectious Diseases 2023 23:458
    Content type: Research Published on:

  7. Hepatitis B virus (HBV) epidemiology in Europe differs by region and population risk group, and data are often incomplete. We estimated chronic HBV prevalence as measured by surface antigen (HBsAg) among gener...

    Authors: Adam Trickey, Sandra Bivegete, Erika Duffell, Anna L. McNaughton, Lina Nerlander, Josephine G. Walker, Hannah Fraser, Matthew Hickman, Peter Vickerman, Ellen Brooks-Pollock and Hannah Christensen
    Citation: BMC Infectious Diseases 2023 23:457
    Content type: Research Published on:

  8. This study aimed to establish multivariate prediction models according to a response-guided therapy (RGT) based strategy at baseline and week 12 and 24 of follow-up to predict the functional cure for HBeAg-neg...

    Authors: Qianqian Tang, Jun Ye, Yafei Zhang, Peixin Zhang, Guomei Xia, Jie Zhu, Shaofeng Wei, Xu Li and Zhenhua Zhang
    Citation: BMC Infectious Diseases 2023 23:456
    Content type: Research Published on:

  10. Remdesivir is widely used for treatment of SARS-CoV-2 pneumonia. The aim of this study was to evaluate the characteristics of patients with moderate-to-severe COVID-19 treated with remdesivir, and their outcom...

    Authors: Filippo Pieralli, Fulvio Pomero, Francesco Dentali, Claudio Norbiato, Tiziana Attardo, Susanna Vicari, Elena Magnani, Maria Antonietta Marzilli, Paola Piccolo, Antonella Valerio and Dario Manfellotto
    Citation: BMC Infectious Diseases 2023 23:454
    Content type: Research Published on:

  11. Chronic active Epstein-Barr virus infection (CAEBV) is a systemic EBV-positive lymphoproliferative disorder (EBV-LPD) considered to be associated with a genetic immunological abnormality, although its cause is...

    Authors: Yaxian Ma, Yuhan Bao and Miao Zheng
    Citation: BMC Infectious Diseases 2023 23:453
    Content type: Case Report Published on:

  12. There has been little research on the long-term clinical outcomes of patients discharged due to undiagnosed fevers of unknown origin (FUO). The purpose of this study was to determine how fever of unknown origi...

    Authors: Lin Jiang, Han Wu, Sen Zhao, Yu Zhang and Ning Song
    Citation: BMC Infectious Diseases 2023 23:452
    Content type: Research Published on:

  13. Osler’s nodes, Janeway lesions and splinter haemorrhages are cutaneous manifestations of infective endocarditis. They occur due to vascular occlusion by septic emboli and a resulting localized vasculitis. They...

    Authors: Pramith Ruwanpathirana, Harindri Athukorala, Praveen Weeratunga and Panduka Karunanayake
    Citation: BMC Infectious Diseases 2023 23:451
    Content type: Case Report Published on:

  14. Disseminated sporotrichosis is a severe opportunistic infection that often affects immunocompromised patients after a cutaneous inoculation. Here we present a rare case of disseminated sporotrichosis discovere...

    Authors: Jennifer L. Perrault, Levi A. Endelman, Mark R. Kraemer, Derrick Chen, Wendell B. Lake and M. Shahriar Salamat
    Citation: BMC Infectious Diseases 2023 23:450
    Content type: Case Report Published on:

  15. Predicting the short-term prognosis and severity of tuberculosis meningitis (TBM) patients without HIV infection can be challenging, and there have been no prior studies examining the neutrophil lymphocyte rat...

    Authors: Zhihan Gu, Bofu Liu, Xiaomin Yu, Tao Cheng, Tianyong Han, Le Tong and Yu Cao
    Citation: BMC Infectious Diseases 2023 23:449
    Content type: Research Published on:

  16. Bloodstream infections (BSI) are a leading cause of morbidity and mortality in hospitalized patients worldwide. A blood culture is the primary tool for determining whether a patient has BSI and requires antimi...

    Authors: Banan M. Aiesh, Duha Daraghmeh, Nasreen Abu-Shamleh, Abdalmenem Joudallah, Ali Sabateen and Rowa’ Al Ramahi
    Citation: BMC Infectious Diseases 2023 23:448
    Content type: Research Published on:

  17. To improve tuberculosis (TB) diagnosis, the World Health Organisation (WHO) has called for a non-sputum based triage test to focus TB testing on people with a high likelihood of having active pulmonary tubercu...

    Authors: Tracy R. Richardson, Bronwyn Smith, Stephanus T. Malherbe, Jane Alexandra Shaw, Firdows Noor, Candice MacDonald, Gian D. van der Spuy, Kim Stanley, Alida Carstens, Tarryn-Lee Fisher, Ilana van Rensburg, Marika Flinn, Candice Snyders, Isaac Johnson, Bernadine Fransman, Hazel Dockrell…
    Citation: BMC Infectious Diseases 2023 23:447
    Content type: Study Protocol Published on:

  18. Due to practical challenges associated with genetic sequencing in low-resource environments, the burden of hepatitis C virus (HCV) in forcibly displaced people is understudied. We examined the use of field app...

    Authors: Anna Yakovleva, Ganna Kovalenko, Matthew Redlinger, Pavlo Smyrnov, Olga Tymets, Anna Korobchuk, Lyudmyla Kotlyk, Anna Kolodiazieva, Anna Podolina, Svitlana Cherniavska, Petro Antonenko, Steffanie A. Strathdee, Samuel R. Friedman, Ian Goodfellow, Joel O. Wertheim, Eric Bortz…
    Citation: BMC Infectious Diseases 2023 23:446
    Content type: Research Published on:

  21. Negative conversion of nucleic acid was a key factor in deciding discharge or the end of isolation of asymptomatic or mild COVID-19 patients. We aimed to explore the effect of vaccination on the time to negati...

    Authors: Yifeng Luo, Qian Zhou, Xinyan Huang, Yuqi Ding, Xiangrong Ye, Jie Ding, Yukun Kuang, Yihao Liu, Sui Peng, Qingtang Zhu, Haibo Wang and Haipeng Xiao
    Citation: BMC Infectious Diseases 2023 23:443
    Content type: Research Published on:

  22. The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pandemic has had an impact on the global tuberculosis (TB) epidemic but evidence on the possible interaction between SARS-CoV-2 and TB, especial...

    Authors: Jeremi Swanepoel, Marieke M. van der Zalm, Wolfgang Preiser, Gert van Zyl, Elizabeth Whittaker, Anneke C. Hesseling, David A. J. Moore and James A. Seddon
    Citation: BMC Infectious Diseases 2023 23:442
    Content type: Research Published on:

  23. Neonatal sepsis is a major cause of health loss and mortality worldwide. Without proper treatment, neonatal sepsis can quickly develop into multisystem organ failure. However, the signs of neonatal sepsis are ...

    Authors: Colleen O’Sullivan, Daniel Hsiang-Te Tsai, Ian Chang-Yen Wu, Emanuela Boselli, Carmel Hughes, Deepak Padmanabhan and Yingfen Hsia
    Citation: BMC Infectious Diseases 2023 23:441
    Content type: Research Published on:

  24. Hydrogen/oxygen therapy contribute to ameliorate dyspnea and disease progression in patients with respiratory diseases. Therefore, we hypothesized that hydrogen/oxygen therapy for ordinary coronavirus disease ...

    Authors: Yingying Zeng, Weijie Guan, Kai Wang, Zhijun Jie, Xu Zou, Xiaoping Tan, Xinyu Li, Xiaohua Chen, Xiaoting Ren, Junhong Jiang, Zeguang Zheng, Jindong Shi and Nanshan Zhong
    Citation: BMC Infectious Diseases 2023 23:440
    Content type: Research Published on:

  25. The vast majority of patients with acute tonsillitis (AT) are managed in general practice. However, occasionally patients are referred to hospital for specialized management because of aggravated symptoms and/...

    Authors: Camilla Andersen, Thomas Greve, Kasper Basse Reinholdt, Ann Marlene Gram Kjaerulff, Nichlas Udholm, Vesal Khalid, Adnan Madzak, Christophe Duez, Henrik Münch, Søren Pauli, Christian Sander Danstrup, Niels Krintel Petersen and Tejs Ehlers Klug
    Citation: BMC Infectious Diseases 2023 23:439
    Content type: Research Published on:

  26. In May 2022, the World Health Organization (WHO) European Region announced an atypical Monkeypox epidemic in response to reports of numerous cases in some member countries unrelated to those where the illness ...

    Authors: Amir Sorayaie Azar, Amin Naemi, Samin Babaei Rikan, Jamshid Bagherzadeh Mohasefi, Habibollah Pirnejad and Uffe Kock Wiil
    Citation: BMC Infectious Diseases 2023 23:438
    Content type: Research Published on:

  27. The emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and subsequent Coronavirus Disease 2019 (COVID-19) pandemic has resulted in a significant global public health burden, leading to a...

    Authors: Guiling Chen, Ying Zhang, Kaiqi Wu, Tinghan Jin, Conggao Peng, Qi Jiang, Wenjuan Tian, Zhong Chen, Zhenwei Shen and Guoping Sheng
    Citation: BMC Infectious Diseases 2023 23:437
    Content type: Research Published on:

  28. This study aimed to investigate the relationship between active pulmonary tuberculosis (TB) and type 2 diabetes mellitus (T2DM) by analysing the clinical features and computed tomography (CT) findings of patie...

    Authors: Qianwen Yang, Rongping Zhang, Yan Gao, Chaoxin Zhou, Weifang Kong, Wang Tao, Guojin Zhang and Lan Shang
    Citation: BMC Infectious Diseases 2023 23:436
    Content type: Research Published on:

  29. Human adenoviruses (HAdV) are a diverse group of viruses causing a broad range of infections of the respiratory, urogenital and gastrointestinal tracts and keratoconjunctivitis. There are seven species of huma...

    Authors: Qouilazoni A. Ukuli, Bernard Erima, Andrew Mubiru, Gladys Atim, Titus Tugume, Hannah Kibuuka, Edison Mworozi, Mariette F. Ducatez, Fred Wabwire-Mangen and Denis K. Byarugaba
    Citation: BMC Infectious Diseases 2023 23:435
    Content type: Research Published on:

  30. The combined infection of actinomyces odontolyticus sepsis and cryptococcal encephalitis is rare in routine clinical practice. Thus, we presented this case report and literature review to provide clues to improve...

    Authors: Qingyu Huang, Zhuquan Hong and Quanlong Hong
    Citation: BMC Infectious Diseases 2023 23:434
    Content type: Case report Published on:

  31. Diagnosis and management of dengue hemorrhagic fever (DHF) can be challenging in the presence of confounding comorbidities. Important confounders are conditions that alter hematological parameters and intra/ex...

    Authors: Manudi Vidanapathirana and Inoshi Atukorala
    Citation: BMC Infectious Diseases 2023 23:433
    Content type: Case Report Published on:

  32. The SARS-CoV-2 virus elicited a major public concern worldwide since December 2019 due to the high number of infections and deaths caused by COVID-19. The Omicron variant was detected in October 2021 which evo...

    Authors: Maryam Arabi, Yousef Al-Najjar, Omna Sharma, Ibtihal Kamal, Aimen Javed, Harsh S. Gohil, Pradipta Paul, Aljazi M. Al-Khalifa, Sa’ad Laws and Dalia Zakaria
    Citation: BMC Infectious Diseases 2023 23:432
    Content type: Research Published on:

  33. Sepsis has a high mortality rate, which is expensive to treat, and is a major drain on healthcare resources; it seriously impacts the quality of human life. The clinical features of positive or non-positive bl...

    Authors: Qiuping Guo, Peng Qu, Wanfu Cui, Mingrong Liu, Huiling Zhu, Weixin Chen, Nan Sun, Shiyu Geng, Weihua Song, Xu Li and Anni Lou
    Citation: BMC Infectious Diseases 2023 23:431
    Content type: Research Published on:

  34. Coccidioidomycosis is a fungal infection endemic to the southwestern United States and regions of Latin America. Disseminated disease occurs in < 1% of cases. Septic shock is even rarer, with high mortality de...

    Authors: Piotr Wisniewski, Isaac McCool, John C. Walsh, Chelsea Ausman, Jenifer Edmondson, Alexandra Perry, Evan C. Ewers and Ryan C. Maves
    Citation: BMC Infectious Diseases 2023 23:430
    Content type: Case Report Published on:

  35. The serial interval is the period of time between symptom onset in the primary case and symptom onset in the secondary case. Understanding the serial interval is important for determining transmission dynamics...

    Authors: Zachary J. Madewell, Yang Yang, Ira M. Longini Jr, M. Elizabeth Halloran, Alessandro Vespignani and Natalie E. Dean
    Citation: BMC Infectious Diseases 2023 23:429
    Content type: Research Published on:

  36. The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has rapidly spread over the world and caused tremendous impacts on global health. Understanding the mechanism responsible for the spread of this...

    Authors: Minh Hanh Nguyen, Thi Huyen Trang Nguyen, Geert Molenberghs, Steven Abrams, Niel Hens and Christel Faes
    Citation: BMC Infectious Diseases 2023 23:428
    Content type: Research Published on:

  37. No research has been conducted to assess whether antibiotic prophylaxis prescribing differs by dental setting. Therefore, the goal of this study was to compare the prescribing of antibiotic prophylaxis in Vete...

    Authors: Swetha Ramanathan, Charlesnika T. Evans, Ronald C. Hershow, Gregory S. Calip, Susan Rowan, Colin Hubbard and Katie J. Suda
    Citation: BMC Infectious Diseases 2023 23:427
    Content type: Research Published on:

  38. . The Mycobacterium tuberculosis Beijing genotype is globally spread lineage with important medical properties that however vary among its subtypes. M. tuberculosis Beijing 14717-15-cluster was recently discovere...

    Authors: Igor Mokrousov, Anna Vyazovaya, Egor Shitikov, Maria Badleeva, Olesya Belopolskaya, Dmitry Bespiatykh, Alena Gerasimova, Panayotis Ioannidis, Weiwei Jiao, Polina Khromova, Aleksey Masharsky, Dinara Naizabayeva, Dimitrios Papaventsis, Oksana Pasechnik, João Perdigão, Nalin Rastogi…
    Citation: BMC Infectious Diseases 2023 23:426
    Content type: Research Published on:

  39. Human bocavirus-1 (hBoV-1) was first detected in respiratory specimens in 2005. Due to high co-infection rates and prolonged shedding of the virus, the pathogenic role of hBoV-1 as a primary causative agent of...

    Authors: Shiyamalee Arunasalam, Thulani Pattiyakumbura, Sibra RM Shihab, Rohitha Muthugala and Faseeha Noordeen
    Citation: BMC Infectious Diseases 2023 23:425
    Content type: Research Published on:

  40. Antimicrobial resistance is one of the ten major public health threats facing humanity, especially in developing countries. Identification of the pathogens responsible for different microbial infections and an...

    Authors: Asmaa K. Helmy, Nagwa M. Sidkey, Ramy E. El-Badawy and Ahmed G. Hegazi
    Citation: BMC Infectious Diseases 2023 23:424
    Content type: Research Published on:

  41. Periprosthetic joint infection (PJI) is one of the most serious complications after total joint arthroplasty (TJA) but the characterization of the periprosthetic environment microbiome after TJA remains unknow...

    Authors: Hao Li, Jun Fu, Niu Erlong, Rui LI, Chi Xu, Libo Hao, Jiying Chen and Wei Chai
    Citation: BMC Infectious Diseases 2023 23:423
    Content type: Research Published on:

  42. Acute gastrointestinal infections can lead to post-infectious irritable bowel syndrome (PI-IBS). Moreover, coronavirus disease (COVID-19) is related to long-term gastrointestinal sequelae. In this study, the f...

    Authors: Daya Zhang, Chen Chen, Yunqian Xie, Fan Zeng, Shiju Chen, Runxiang Chen, Xiaodong Zhang, Shimei Huang, Da Li and Feihu Bai
    Citation: BMC Infectious Diseases 2023 23:422
    Content type: Research Published on:

  43. The private sector is an important yet underregulated component of the TB treatment infrastructure in India. The Joint Effort for Elimination of Tuberculosis (Project JEET) aims to link private sector TB care ...

    Authors: Ridhima Sodhi, Michael J. Penkunas and Arnab Pal
    Citation: BMC Infectious Diseases 2023 23:421
    Content type: Research Published on:

  44. Diphtheria is a severe respiratory or cutaneous infectious disease, caused by exotoxin producing Corynebacterium diphtheriae, C. ulcerans and C. pseudotuberculosis. Diphtheria is once again prevalent due to break...

    Authors: Jelte Elsinga, Dimphey van Meijeren and Frans Reubsaet
    Citation: BMC Infectious Diseases 2023 23:420
    Content type: Research Published on:

  45. Lingering symptoms after acute COVID-19 present a major challenge to ambulatory care services. Since there are reservations regarding their optimal management, we aimed to collate all available evidence on the...

    Authors: Hannelore Dillen, Geertruida Bekkering, Sofie Gijsbers, Yannick Vande Weygaerde, Maarten Van Herck, Sarah Haesevoets, David A G Bos, Ann Li, Wim Janssens, Rik Gosselink, Thierry Troosters and Jan Y Verbakel
    Citation: BMC Infectious Diseases 2023 23:419
    Content type: Research article Published on:

  46. In vitro diagnostics (IVDs) for primary detection test/screening of human T-cell leukemia virus (HTLV) have recently been updated to new-generation products in Japan. In this study, the performance of these pr...

    Authors: Shigeru Kusagawa, Ai Kawana-Tachikawa, Keiji Matsubayashi, Rieko Sobata and Isao Hamaguchi
    Citation: BMC Infectious Diseases 2023 23:418
    Content type: Research Published on:

  47. Previous studies found minimal evidence and raised controversy about the link between hemoglobin and 28-day mortality in sepsis patients. As a result, the purpose of this study was to examine the association b...

    Authors: Yu Chen, Lu Chen, Zengping Meng, Yi Li, Juan Tang, Shaowen Liu, Li Li, Peisheng Zhang, Qian Chen and Yongmei Liu
    Citation: BMC Infectious Diseases 2023 23:417
    Content type: Research Published on:

  48. Salmonella enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever. Salmonella Typhi may be transmitted through shedding in the stool, which can continue after recovery from acute illness. Sheddin...

    Authors: Peter I. Johnston, Patrick Bogue, Angeziwa Chunga Chirambo, Maurice Mbewe, Reenesh Prakash, Vanessa Kandoole-Kabwere, Rebecca Lester, Thomas Darton, Stephen Baker, Melita A. Gordon and James E. Meiring
    Citation: BMC Infectious Diseases 2023 23:416
    Content type: Research Published on:

  49. A key factor driving the development and maintenance of antibacterial resistance (ABR) is individuals’ use of antibiotics (ABs) to treat illness. To better understand motivations and context for antibiotic use...

    Authors: Katherine Keenan, Kathryn J. Fredricks, Mary Abed Al Ahad, Stella Neema, Joseph R. Mwanga, Mike Kesby, Martha F. Mushi, Annette Aduda, Dominique L. Green, Andy G. Lynch, Sarah I. Huque, Blandina T. Mmbaga, Hannah Worthington, Catherine Kansiime, Emmanuel Olamijuwon, Nyanda E. Ntinginya…
    Citation: BMC Infectious Diseases 2023 23:414
    Content type: Research Published on:

  50. Rapid and accurate identification of carbapenemase-producing organism (CPO) intestinal carriers is essential for infection prevention and control. Molecular diagnostic methods can produce results in as little ...

    Authors: Yue Wang, Huijuan Song, Min Xu, Dengju Li, Xiao Ran, Ziyong Sun and Zhongju Chen
    Citation: BMC Infectious Diseases 2023 23:413
    Content type: Research Published on:

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