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  1. Despite the availability of effective antibiotic therapies, pneumococcal meningitis (PM) has a case fatality rate of up to 30% and causes neurological sequelae in up to half of the surviving patients. The unde...

    Authors: Matthias Wittwer, Denis Grandgirard, Janine Rohrbach and Stephen L Leib
    Citation: BMC Infectious Diseases 2010 10:176
  2. The prevalence of pulmonary tuberculosis among college students in Shaanxi is high. Although tuberculosis leaves much psychological and social impact on patients, little is known about its impact on college st...

    Authors: Shao-Ru Zhang, Hong Yan, Jin-Jing Zhang, Tian-Hua Zhang, Xiao-Hong Li and Yin-Ping Zhang
    Citation: BMC Infectious Diseases 2010 10:174
  3. Previous studies, conducted in the urban of Antananarivo, showed low rate of confirmed malaria cases. We used a geographical and environmental approach to investigate the contribution of environmental factors ...

    Authors: Fanjasoa Rakotomanana, Jocelyn Ratovonjato, Rindra V Randremanana, Laurence Randrianasolo, Rogelin Raherinjafy, Jean-Paul Rudant and Vincent Richard
    Citation: BMC Infectious Diseases 2010 10:173
  4. To ensure sustainable routine surveillance of mosquito vectors, simple, effective and ethically acceptable tools are required. As a part of that, we evaluated the efficiency of resting boxes baited with fresh ...

    Authors: Aneth M Mahande, Beda J Mwang'onde, Shandala Msangi, Epiphania Kimaro, Ladslaus L Mnyone, Humphrey D Mazigo, Michael J Mahande and Eliningaya J Kweka
    Citation: BMC Infectious Diseases 2010 10:172
  5. To examine common antimicrobial regimens used in eradicating certain nosocomial Gram-negative pathogens and determine which ones are likely to be the most suitable as empirical choices in Shenyang, China.

    Authors: Yun Zhuo Chu, Su Fei Tian, Bai Yi Chen, Hua Nian, Hong Shang and Guo Quan Sun
    Citation: BMC Infectious Diseases 2010 10:171
  6. The use of cell culture for the diagnosis of human metapneumovirus (hMPV) infection is uncommon at present and molecular method such as reverse-transcription PCR (RT-PCR) has been widely and most commonly used...

    Authors: Yoko Matsuzaki, Katsumi Mizuta, Emi Takashita, Michiko Okamoto, Tsutomu Itagaki, Fumio Katsushima, Yuriko Katsushima, Yukio Nagai and Hidekazu Nishimura
    Citation: BMC Infectious Diseases 2010 10:170
  7. Previous studies have indicated an increased risk of myocardial infarction (MI) in HIV infected individuals especially after start of highly active antiretroviral therapy (HAART). It is however controversial w...

    Authors: Line D Rasmussen, Lars H Omland, Court Pedersen, Jan Gerstoft, Gitte Kronborg, Janne Jensen and Niels Obel
    Citation: BMC Infectious Diseases 2010 10:169
  8. Influenza vaccination in infants and children with existing health complications is current practice in many countries, but healthy children are also susceptible to influenza, sometimes with complications. The...

    Authors: Vytautas Usonis, Ioana Anca, Francis André, Roman Chlibek, Inga Ivaskeviciene, Atanas Mangarov, Zsófia Mészner, Roman Prymula, Pavol Šimurka, Eda Tamm and Goran Tešović
    Citation: BMC Infectious Diseases 2010 10:168
  9. The role of adaptive immunity in severe influenza is poorly understood. The occurrence of influenza A/H5N1 in a patient with HIV provided a rare opportunity to investigate this.

    Authors: Annette Fox, Peter Horby, Nguyen Hong Ha, Le Nguyen Minh Hoa, Nguyen Tien Lam, Cameron Simmons, Jeremy Farrar, Nguyen Van Kinh and Heiman Wertheim
    Citation: BMC Infectious Diseases 2010 10:167
  10. Mathematical models of infection that consider targeted interventions are exquisitely dependent on the assumed mixing patterns of the population. We report on a pilot study designed to assess three different m...

    Authors: James M McCaw, Kristian Forbes, Paula M Nathan, Philippa E Pattison, Garry L Robins, Terence M Nolan and Jodie McVernon
    Citation: BMC Infectious Diseases 2010 10:166
  11. Pulmonary tuberculosis, the most common clinical form of mycobacterial diseases, is a granulomatous disease of the lungs caused by Mycobaterium tuberculosis. A number of genes have been identified in studies of d...

    Authors: Shilpy Sharma, Jaishriram Rathored, Balaram Ghosh and Surendra K Sharma
    Citation: BMC Infectious Diseases 2010 10:165
  12. Anti-viral prophylaxis is used to prevent the transmission of influenza. We studied serological confirmation of 2009 Influenza A (H1N1) infections during oseltamivir prophylaxis and after cessation of prophyla...

    Authors: Vernon J Lee, Jonathan Yap, Joshua K Tay, Ian Barr, Qiuhan Gao, Hanley J Ho, Boon Huan Tan, Paul M Kelly, Paul A Tambyah, Anne Kelso and Mark I Chen
    Citation: BMC Infectious Diseases 2010 10:164
  13. Resistance of the malaria parasite Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) has evolved worldwide. In the archipelago of São Tomé and Principe (STP), West Africa, although SP resistance is highly p...

    Authors: Patrícia Salgueiro, José L Vicente, Conceição Ferreira, Vânia Teófilo, André Galvão, Virgílio E do Rosário, Pedro Cravo and João Pinto
    Citation: BMC Infectious Diseases 2010 10:163
  14. Several studies have shown a relatively high mortality rate among young people infected by the 2009 pandemic influenza A (H1N1) virus. Here we compared the age distributions of morbidity and mortality during t...

    Authors: Magali Lemaitre and Fabrice Carrat
    Citation: BMC Infectious Diseases 2010 10:162
  15. Tuberculosis is a highly infectious disease that is spread from person to person by infected aerosols emitted by patients with respiratory forms of the disease. We describe a novel device that utilizes immunos...

    Authors: Ruth McNerney, Beyene A Wondafrash, Kebede Amena, Ato Tesfaye, Elaine M McCash and Nicol J Murray
    Citation: BMC Infectious Diseases 2010 10:161
  16. Previous studies regarding the prognosis of patients infected with MRSA isolates characterized by a high minimum inhibitory concentration (MIC) for vancomycin have generally used a commercial Etest. Little res...

    Authors: Jiun-Ling Wang, Jann-Tay Wang, Wang-Huei Sheng, Yee-Chun Chen and Shan-Chwen Chang
    Citation: BMC Infectious Diseases 2010 10:159
  17. Vertebral osteomyelitis is a common manifestation of osteomyelitis in adults and associated with considerable morbidity. Limited data exist regarding hematogenous vertebral osteomyelitis. Our objective was to ...

    Authors: Kavita P Bhavan, Jonas Marschall, Margaret A Olsen, Victoria J Fraser, Neill M Wright and David K Warren
    Citation: BMC Infectious Diseases 2010 10:158
  18. There is conclusive evidence that human papillomavirus (HPV) infections of the cervix are a necessary cause of cervical cancer. In Italy there are consistent data of HPV prevalence in women aged 25 - 64 years,...

    Authors: Massimo Confortini, Francesca Carozzi, Marco Zappa, Leonardo Ventura, Anna Iossa, Paola Cariaggi, Livia Brandigi, Mario Franchini, Francesco Mirri, Paolo Viacava, Aurora Scarfantoni, Daniela Bazzanti and Cristina Sani
    Citation: BMC Infectious Diseases 2010 10:157
  19. Smoking is known to aggravate tuberculosis (TB), but such information has been ignored in clinical practice, as it was not thought to be relevant. The aim of this study is to assess the benefits of smoking ces...

    Authors: Chi-Pang Wen, Ta-Chien Chan, Hui-Ting Chan, Min-Kuang Tsai, Ting-Yuang Cheng and Shan-Pou Tsai
    Citation: BMC Infectious Diseases 2010 10:156
  20. The first imported case of pandemic influenza (H1N1) 2009 in Germany was confirmed in April 2009. However, the first wave with measurable burden of disease started only in October 2009. The basic epidemiologic...

    Authors: Gabriele Poggensee, Andreas Gilsdorf, Silke Buda, Tim Eckmanns, Hermann Claus, Doris Altmann, Gérard Krause and Walter Haas
    Citation: BMC Infectious Diseases 2010 10:155
  21. Interferon gamma is a major macrophage-activating cytokine during infection with Mycobacterium tuberculosis, the causative pathogen of tuberculosis, and its role has been well established in animal models and in ...

    Authors: Marlo Möller, Almut Nebel, Paul D van Helden, Stefan Schreiber and Eileen G Hoal
    Citation: BMC Infectious Diseases 2010 10:154
  22. Oxacillin continues to be an important agent in the treatment of staphylococcal infections; many generic products are available and the only requirement for their approval is demonstration of pharmaceutical eq...

    Authors: Carlos A Rodriguez, Maria Agudelo, Andres F Zuluaga and Omar Vesga
    Citation: BMC Infectious Diseases 2010 10:153
  23. HMG CoA reductase inhibitors (statins) in patients with bacteremic sepsis have shown significant survival benefits in several studies. There is no data on the effect of statins in candidemic patients, however ...

    Authors: Graeme N Forrest, Angela M Kopack and Eli N Perencevich
    Citation: BMC Infectious Diseases 2010 10:152
  24. Candida represents the most common cause of invasive fungal disease, and candidal blood stream infections (CBSI) are prevalent in the ICU. Inappropriate antifungal therapy (IAT) is known to increase a patient'...

    Authors: Marya D Zilberberg, Marin H Kollef, Heather Arnold, Andrew Labelle, Scott T Micek, Smita Kothari and Andrew F Shorr
    Citation: BMC Infectious Diseases 2010 10:150
  25. To control multidrug resistant tuberculosis (MDR-TB), the drug susceptibility profile is needed to guide therapy. Classical drug susceptibility testing (DST) may take up to 2 to 4 months. The GenoType® MTBDRplus ...

    Authors: Mai NT Huyen, Edine W Tiemersma, Nguyen TN Lan, Frank GJ Cobelens, Nguyen H Dung, Dinh N Sy, Tran N Buu, Kristin Kremer, Pham T Hang, Maxine Caws, Richard O'Brien and Dick van Soolingen
    Citation: BMC Infectious Diseases 2010 10:149
  26. Antibiotics are not only small molecules with therapeutic activity in killing or inhibiting microbial growth, but can also act as signaling molecules affecting gene expression in bacterial communities. A few s...

    Authors: Fedora Babić, Vittorio Venturi and Gordana Maravić-Vlahoviček
    Citation: BMC Infectious Diseases 2010 10:148
  27. Human cytomegalovirus (CMV) infection still causes significant morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Therefore, it is extremely important to diagnosis and mon...

    Authors: Renata MB Peres, Cláudia RC Costa, Paula D Andrade, Sandra HA Bonon, Dulcinéia M Albuquerque, Cristiane de Oliveira, Afonso C Vigorito, Francisco JP Aranha, Cármino A de Souza and Sandra CB Costa
    Citation: BMC Infectious Diseases 2010 10:147
  28. Because of better comfort, air conditioning systems are a common feature in automobiles these days. However, its impact on the number of particles and microorganisms inside the vehicle - and by this its impact...

    Authors: Ralf-Peter Vonberg, Petra Gastmeier, Björn Kenneweg, Hinrich Holdack-Janssen, Dorit Sohr and Iris F Chaberny
    Citation: BMC Infectious Diseases 2010 10:146
  29. During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. We describe the clinical characteristics and factors associated with the death of patients who were hospitalized with...

    Authors: Wei Cui, Hongwen Zhao, Xu Lu, Ying Wen, Ying Zhou, Baocheng Deng, Yu Wang, Wen Wang, Jian Kang and Pei Liu
    Citation: BMC Infectious Diseases 2010 10:145
  30. Salmonella Typhi (S. Typhi) causes typhoid fever, which remains an important public health issue in many developing countries. Kathmandu, the capital of Nepal, is an area of high incidence and the pediatric popu...

    Authors: Kathryn E Holt, Stephen Baker, Sabina Dongol, Buddha Basnyat, Neelam Adhikari, Stephen Thorson, Anoop S Pulickal, Yajun Song, Julian Parkhill, Jeremy J Farrar, David R Murdoch, Dominic F Kelly, Andrew J Pollard and Gordon Dougan
    Citation: BMC Infectious Diseases 2010 10:144
  31. Febrile neutropenia carries a high risk of sepsis complications, and the identification of biomarkers capable to identify high risk patients is a great challenge. Angiopoietins (Ang -) are cytokines involved i...

    Authors: Brunna E Alves, Silmara AL Montalvao, Franciso JP Aranha, Tania FG Siegl, Carmino A Souza, Irene Lorand-Metze, Joyce M Annichino-Bizzacchi and Erich V De Paula
    Citation: BMC Infectious Diseases 2010 10:143
  32. Dengue is a major public health problem in tropical and subtropical countries. Rapid and easy diagnosis of dengue can assist patient triage and care-management. The detection of DENV NS1 on rapid lateral flow ...

    Authors: Vianney Tricou, Hang TT Vu, Nhu VN Quynh, Chau VV Nguyen, Hien T Tran, Jeremy Farrar, Bridget Wills and Cameron P Simmons
    Citation: BMC Infectious Diseases 2010 10:142
  33. The detailed analysis of an outbreak database has been undertaken to examine the role of contact tracing in controlling an outbreak of possible avian influenza in humans. The outbreak, initiating from the purc...

    Authors: Ken TD Eames, Cerian Webb, Kathrin Thomas, Josie Smith, Roland Salmon and J Mark F Temple
    Citation: BMC Infectious Diseases 2010 10:141
  34. In tuberculosis (TB) endemic parts of the world, patients with pulmonary symptoms are managed as "smear-negative TB patients" if they do not improve on a two-week presumptive, broad-spectrum course of antibiot...

    Authors: Lotte Jensen, Andreas V Jensen, George Praygod, Jeremiah Kidola, Daniel Faurholt-Jepsen, John Changalucha, Nyagosya Range, Henrik Friis, Jannik Helweg-Larsen, Jorgen S Jensen and Aase B Andersen
    Citation: BMC Infectious Diseases 2010 10:140
  35. During the SARS pandemic in Hong Kong, panic and worry were prevalent in the community and the general public avoided staying in public areas. Such avoidance behaviors could greatly impact daily routines of th...

    Authors: Joseph TF Lau, Sian Griffiths, Kai Chow Choi and Hi Yi Tsui
    Citation: BMC Infectious Diseases 2010 10:139
  36. Recent interest has focused on the potential use of serial interferon gamma (IFN-γ) release assay (IGRA) measurements to assess the response to anti-tuberculous (TB) treatment. The kinetics of IFN-γ responses to

    Authors: Tom G Connell, Mary-Ann Davies, Christine Johannisen, Kathryn Wood, Sandy Pienaar, Katalin A Wilkinson, Robert J Wilkinson, Heather J Zar, David Beatty, Mark P Nicol, Nigel Curtis and Brian Eley
    Citation: BMC Infectious Diseases 2010 10:138
  37. The objective of this study was to estimate the effect of male circumcision (MC) on HIV acquisition estimated using HIV incidence assays and to compare it to the effect measured by survival analysis.

    Authors: Agnès Fiamma, Pascale Lissouba, Oliver E Amy, Beverley Singh, Oliver Laeyendecker, Thomas C Quinn, Dirk Taljaard and Bertran Auvert
    Citation: BMC Infectious Diseases 2010 10:137
  38. In infectious disease surveillance, when the laboratory confirmation of the cases is time-consuming, there is often a time lag between the number of suspect cases and the number of confirmed cases. This study ...

    Authors: Pei-Hung Chuang, Jen-Hsiang Chuang and I-Feng Lin
    Citation: BMC Infectious Diseases 2010 10:136
  39. Bloodstream Infections (BSIs) in neutropenic patients often cause considerable morbidity and mortality. Therefore, the surveillance and early identification of patients at high risk for developing BSIs might b...

    Authors: Eleni Apostolopoulou, Vasilios Raftopoulos, Konstantinos Terzis and Ioannis Elefsiniotis
    Citation: BMC Infectious Diseases 2010 10:135
  40. Although seasonal influenza vaccine is effective in the elderly, immune responses to vaccination are lower in the elderly than in younger adults. Strategies to optimise responses to vaccination in the elderly ...

    Authors: Pierre Van Damme, Robert Arnou, Froukje Kafeja, Anne Fiquet, Patrick Richard, Stéphane Thomas, Gilles Meghlaoui, Sandrine Isabelle Samson and Emilio Ledesma
    Citation: BMC Infectious Diseases 2010 10:134
  41. Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA), is an important cause of pyogenic skin and soft tissue infections (SSTIs). The aim of present study is to investigate the molecular cha...

    Authors: Dan Yao, Fang-you Yu, Zhi-qiang Qin, Chun Chen, Su-su He, Zeng-qiang Chen, Xue-qing Zhang and Liang-xing Wang
    Citation: BMC Infectious Diseases 2010 10:133
  42. Nephropathia epidemica (NE) is a Scandinavian type of hemorrhagic fever with renal syndrome caused by Puumala hantavirus. The clinical course of the disease varies greatly in severity. The aim of the present s...

    Authors: Tuula K Outinen, Satu M Mäkelä, Ilpo O Ala-Houhala, Heini SA Huhtala, Mikko Hurme, Antti S Paakkala, Ilkka H Pörsti, Jaana T Syrjänen and Jukka T Mustonen
    Citation: BMC Infectious Diseases 2010 10:132
  43. Effective highly active antiretroviral therapy (HAART) reduces human immunodeficiency virus (HIV) replication, restores CD4+ T lymphocyte counts and greatly reduces the incidence of opportunistic infections. Whil...

    Authors: Julia Pohling, Katrin Zipperlen, Natasha A Hollett, Maureen E Gallant and Michael D Grant
    Citation: BMC Infectious Diseases 2010 10:129
  44. The ecology of influenza may be more complex than is usually assumed. For example, despite multiple waves in the influenza pandemic of 1918-19, many people in urban locations were apparently unaffected. Were t...

    Authors: John D Mathews, Emma S McBryde, Jodie McVernon, Paul K Pallaghy and James M McCaw
    Citation: BMC Infectious Diseases 2010 10:128
  45. Sexually transmitted infections (STIs) and Reproductive tract infections (RTIs) are responsible for high morbidity among women. We aim to quantify the magnitude of the burden and risk factors of STI/RTI s amon...

    Authors: Nyaradzai E Kurewa, Munyaradzi P Mapingure, Marshal W Munjoma, Mike Z Chirenje, Simbarashe Rusakaniko and Babill Stray-Pedersen
    Citation: BMC Infectious Diseases 2010 10:127
  46. PCR amplification for the detection of pathogens in biological material is generally considered a rapid and informative diagnostic technique. Invasive Salmonella serovars, which cause enteric fever, can be common...

    Authors: Tran Vu Thieu Nga, Abhilasha Karkey, Sabina Dongol, Hang Nguyen Thuy, Sarah Dunstan, Kathryn Holt, Le Thi Phuong Tu, James I Campbell, Tran Thuy Chau, Nguyen Van Vinh Chau, Amit Arjyal, Samir Koirala, Buddha Basnyat, Christiane Dolecek, Jeremy Farrar and Stephen Baker
    Citation: BMC Infectious Diseases 2010 10:125

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