Volume 13 Supplement 1

Proceedings of the 9th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof Dr Matei Bals”

Open Access

Peculiar evolution of streptococcal skin infections

BMC Infectious Diseases201313(Suppl 1):P66

https://doi.org/10.1186/1471-2334-13-S1-P66

Published: 16 December 2013

Background

Acute Streptococcus pyogenes infections may present under various forms, such as pharyngitis, scarlet fever, pneumonia, meningitis, cellulitis or impetigo. Toxigenic infections can result in necrotizing fasciitis, myositis and streptococcal toxic shock syndrome. Following acute infections caused by S pyogenes, patients are also at risk for developing immune-mediated post-streptococcal sequelae, as is the case with acute rheumatic fever and acute glomerulonephritis.

Methods

We performed a hospital based study from January 2012 to December 2012 in the Clinic of Infectious Diseases Oradea.

Results

A total number of 192 patients were studied during a one-year period: 25 cases of impetigo and erysipelas, in parallel with 84 cases of tonsillitis, 36 cases of scarlet fever, 10 cases of acute rheumatic fever, 8 cases of chronic rheumatic heart disease, 6 cases of acute post streptococcal glomerulonephritis, 2 cases of streptococcal meningitis, and 31 cases of healthy carriers of S pyogenes.

Impetigo dominated in children (7 cases – 70%) vs. adults (3 cases – 30%); erysipelas dominated in adults, especially over 40 years (13 cases – 86%) vs. children (2 cases – 14%). From the 25 patients admitted in the hospital with the diagnosis of erysipelas, 11 patients (60%) declared one or more (5) recurrences in the same part of the body. In rheumatic fever, approximately 80% of the patients will have an elevated ASO titer (>200 Todd units) at 2 months after onset.

Conclusion

The type and severity of streptococcal infections depends on the strain of S pyogenes and on the comorbid conditions or diseases, like heart, pulmonary, renal, metabolic chronic diseases, obesity or lymphatic stasis.

The septic, toxic and the immune complications of streptococcal infections pose important problems for the public health services.

Authors’ Affiliations

(1)
Faculty of Medicine and Pharmacy, University of Oradea

Copyright

© Drăghici and Csep; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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