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Current clinical and therapeutic issues in measles


Known since antiquity (the etiological agent was discovered much later), measles continues to be a problem of infectious pathology present in Romania and in many other countries.


We have studied a total of 503 cases admitted to the Infectious Diseases II Clinic of Infectious Diseases and Pneumology Hospital of Timişoara between 2011-2012.


Measles still represents a common disease among infants and young children, fact confirmed in our study by the high number of cases: 331 (65%). The most common complications in children were the respiratory and ENT infections. The number of measles cases was higher in 2011 compared to 2012 which coincides with data reported by other countries.


The absence of vaccination from multiple reasons explained the increased number of measles cases (with significant variations in county level). Eradication of measles has been proposed by many countries, e.g. USA, France for over 10 years without being actually realized. In 1993, the measles virus was more neurotropic (there were many cases of deadly encephalitis) compared to the virus strain from 2011-2012.

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Correspondence to Narcisa Nicolescu.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Nicolescu, N., Crisan, A., Nicoară, E. et al. Current clinical and therapeutic issues in measles. BMC Infect Dis 13 (Suppl 1), P106 (2013).

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