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  1. Directly observed therapy (DOT), as recommended by the World Health Organization, is used in many countries to deliver tuberculosis (TB) treatment. The effectiveness of community-based (CB DOT) versus clinic D...

    Authors: Cameron M Wright, Lenna Westerkamp, Sarah Korver and Claudia C Dobler
    Citation: BMC Infectious Diseases 2015 15:210
    Content type: Research article Published on:

  2. Mycobacterium tuberculosis (TB) infection of the liver, known as hepatic TB, is an extrapulmonary manifestation of TB. Hepatic TB has become more prevalent, likely as a result of the human immunodeficiency virus/...

    Authors: Andrew J Hickey, Lilishia Gounder, Mahomed-Yunus S Moosa and Paul K Drain
    Citation: BMC Infectious Diseases 2015 15:209
    Content type: Research article Published on:

  3. Truck drivers constitute an important bridging group in the HIV epidemic in Morocco. This study examined the effect of a community-based educational intervention in Morocco on HIV testing and counseling, in re...

    Authors: Hakima Himmich, Lahoucine Ouarsas, Fatima Zahra Hajouji, Caroline Lions, Perrine Roux and Patrizia Carrieri
    Citation: BMC Infectious Diseases 2015 15:208
    Content type: Research article Published on:

  5. Fibrosing mediastinitis (FM) is an idiosyncratic reaction to infection with Histoplasma capsulatum with a prevalence of 3:100,000 people infected. The rarity of post-histoplasmosis fibrosing mediastinitis (PHFM) ...

    Authors: Stephen B Strock, Silvana Gaudieri, Simon Mallal, Chang Yu, Daphne Mitchell, Joy Cogan, Wendi Mason, Deborah Crowe and James E Loyd
    Citation: BMC Infectious Diseases 2015 15:206
    Content type: Research article Published on:

  6. Fungal infections represent a major burden in the critical care setting with increasing morbidity and mortality. Candidiasis is the leading cause of such infections, with C. albicans being the most common causati...

    Authors: Dimitrios K Matthaiou, Theodora Christodoulopoulou and George Dimopoulos
    Citation: BMC Infectious Diseases 2015 15:205
    Content type: Review Published on:

  7. Although malaria is preventable and treatable, it still claims 660,000 lives every year globally with children under five years of age having the highest burden. In Zambia, malaria rapid diagnostic tests (RDTs...

    Authors: Lungowe Sitali, James Chipeta, John M Miller, Hawela B Moonga, Nirbhay Kumar, William J Moss and Charles Michelo
    Citation: BMC Infectious Diseases 2015 15:204
    Content type: Research article Published on:

  8. Hepatitis B virus (HBV) vaccine antibody response has been associated with reduced risk of AIDS or death. However, it is unknown whether HBV vaccine responsiveness is associated with improved immune reconstitu...

    Authors: Kahtonna Allen, Octavio Mesner, Anuradha Ganesan, Thomas A O’Bryan, Robert G Deiss, Brian K Agan and Jason F Okulicz
    Citation: BMC Infectious Diseases 2015 15:203
    Content type: Research article Published on:

  10. Over the last two decades, the proportion of people who inject drugs among newly reported HIV cases in Italy has been continuously declining. This trend is reflected in the prevalence of HIV infection among pr...

    Authors: Mario Cruciani, Lucas Wiessing, Giovanni Serpelloni, Bruno Genetti, Alessandra Andreotti, Carpignano Iulia, Monica Zermiani and Barbara Suligoi
    Citation: BMC Infectious Diseases 2015 15:201
    Content type: Research article Published on:

  11. Single-dose azithromycin is recommended over multi-dose doxycycline as treatment for chlamydial infection. However, even with imperfect adherence, doxycycline is more effective in treating genital and rectal i...

    Authors: Andrew P Craig, Fabian YS Kong, Laxmi Yeruva, Jane S Hocking, Roger G Rank, David P Wilson and Basil Donovan
    Citation: BMC Infectious Diseases 2015 15:200
    Content type: Research article Published on:

  12. Sepsis is a serious medical condition requiring timely administered, appropriate antibiotic therapy. Blood culture is regarded as the gold standard for aetiological diagnosis of sepsis, but it suffers from low...

    Authors: Lars Ljungström, Helena Enroth, Berndt EB Claesson, Ida Ovemyr, Jesper Karlsson, Berit Fröberg, Anna-Karin Brodin, Anna-Karin Pernestig, Gunnar Jacobsson, Rune Andersson and Diana Karlsson
    Citation: BMC Infectious Diseases 2015 15:199
    Content type: Research article Published on:

  13. The 29 kDa Schistosoma haematobium species-specific antigen (ShSSA) is of remarkable interest in the diagnosis of urinary schistosomiasis although it had not been fully characterized.

    Authors: Uri S Markakpo, George E Armah, Julius N Fobil, Richard H Asmah, Isaac Anim-Baidoo, Alfred K Dodoo, Parnor Madjitey, Edward E Essuman, Somei Kojima and Kwabena M Bosompem
    Citation: BMC Infectious Diseases 2015 15:198
    Content type: Research article Published on:

  14. Comparison of antimicrobial de-escalation rates between healthcare settings is problematic. To objectively and electronically measure de-escalation a method based upon the spectrum of antimicrobial regimens ad...

    Authors: Karl Madaras-Kelly, Makoto Jones, Richard Remington, Christina Caplinger, Benedikt Huttner and Matthew Samore
    Citation: BMC Infectious Diseases 2015 15:197
    Content type: Technical advance Published on:

  15. The leprosy transmission chain is very complex and, in order to intervene in this transmission, more must be known about the factors linked to falling ill. There are doubts as to the influence of population si...

    Authors: Mônica Duarte-Cunha, Geraldo Marcelo da Cunha and Reinaldo Souza-Santos
    Citation: BMC Infectious Diseases 2015 15:196
    Content type: Research article Published on:

  16. Little is known about factors associated with maintenance of hemagglutinin inhibition (HAI) antibodies after influenza vaccination in older adults.

    Authors: H Keipp Talbot, Laura A Coleman, Yuwei Zhu, Sarah Spencer, Mark Thompson, Po-Yung Cheng, Maria E Sundaram, Edward A Belongia and Marie R Griffin
    Citation: BMC Infectious Diseases 2015 15:195
    Content type: Research article Published on:

  17. HIV infection is a risk factor for Clostridium difficile infection (CDI) yet the immune deficiency predisposing to CDI is not well understood, despite an increasing incidence of CDI among such individuals. We aim...

    Authors: Stefano Di Bella, Alexander W Friedrich, Esther García-Almodóvar, Maria Serena Gallone, Fabrizio Taglietti, Simone Topino, Vincenzo Galati, Emma Johnson, Silvia D’Arezzo and Nicola Petrosillo
    Citation: BMC Infectious Diseases 2015 15:194
    Content type: Research article Published on:

  18. Among people living with HIV/AIDS, illicit drug use is a risk for sub-optimal treatment outcomes. However, few studies have examined the relative contributions of different patterns of drug use on adherence to...

    Authors: Pouya Azar, Evan Wood, Paul Nguyen, Maxo Luma, Julio Montaner, Thomas Kerr and M-J Milloy
    Citation: BMC Infectious Diseases 2015 15:193
    Content type: Research article Published on:

  20. Clostridium difficile infection (CDI), a complication of antibiotic-induced injury to the gut microbiome, is a prevalent and dangerous cause of infectious diarrhea. Antimicrobial thera...

    Authors: Bruce E Hirsch, Nimit Saraiya, Kaitlin Poeth, Rebecca M Schwartz, Marcia E Epstein and Gerard Honig
    Citation: BMC Infectious Diseases 2015 15:191
    Content type: Research article Published on:

  21. Tissue factor (TF) is a protein that mediates the initiation of the coagulation cascade. TF expression is increased in patients with poorly-controlled HIV, and may be associated with increased immune activatio...

    Authors: Aimee C Hodowanec, Rebecca D Lee, Kirsten E Brady, Weihua Gao, Stacey Kincaid, Jill Plants, Mieoak Bahk, Nigel Mackman, Alan L Landay and Gregory D Huhn
    Citation: BMC Infectious Diseases 2015 15:190
    Content type: Research article Published on:

  22. Syphilis facilitates both HIV (human immunodeficiency virus) transmission and acquisition, reflecting the complex interplay between the two infections. Scarce information exists regarding syphilis epidemiology...

    Authors: Techalew Shimelis, Kinfe Lemma, Henock Ambachew and Endale Tadesse
    Citation: BMC Infectious Diseases 2015 15:189
    Content type: Research article Published on:

  23. Visceral leishmaniasis (VL), a potentially fatal disease, is most prevalent in the Indian subcontinent, East Africa and South America. Since the conventional antileishmanial drugs have many limitations we eval...

    Authors: Mohammad Asad, Pradyot Bhattacharya, Antara Banerjee and Nahid Ali
    Citation: BMC Infectious Diseases 2015 15:188
    Content type: Research article Published on:

  24. After more than a decade of establishing and expanding access to highly active antiretroviral therapy (HAART), empirical evidence on its impact on trends of opportunistic infections (OIs) associated with the d...

    Authors: John Rubaihayo, Nazarius M Tumwesigye and Joseph Konde-Lule
    Citation: BMC Infectious Diseases 2015 15:187
    Content type: Research article Published on:

  25. Influenza vaccination is recommended for all healthcare personnel (HCP) and most institutions offer vaccination for free and on site. However, medical students do not always have such easy access, and the pred...

    Authors: Birthe A Lehmann, Robert AC Ruiter, Sabine Wicker, Gretchen Chapman and Gerjo Kok
    Citation: BMC Infectious Diseases 2015 15:185
    Content type: Research article Published on:

  26. Survivors of combat trauma can have long and challenging recoveries, which may be complicated by infection. Invasive fungal infections are a rare but serious complication with limited treatment options. Curren...

    Authors: Kevin S Akers, Matthew P Rowan, Krista L Niece, John C Graybill, Katrin Mende, Kevin K Chung and Clinton K Murray
    Citation: BMC Infectious Diseases 2015 15:184
    Content type: Case report Published on:

  27. Norovirus is an important cause of gastroenteritis both in children and adults. In China, few studies have been conducted on adult populations. This study aimed to determine the contribution of norovirus to ga...

    Authors: Ying Xue, Hao Pan, Jiayu Hu, Huanyu Wu, Jian Li, Wenjia Xiao, Xi Zhang, Zheng’an Yuan and Fan Wu
    Citation: BMC Infectious Diseases 2015 15:183
    Content type: Research article Published on:

  28. Inflammatory myelopathy is an inflammatory neurological disorder of the spinal cord (myelopathy). It occurs in 1 (severe) to 8 (mild) cases/million per year. It is often referred to in the literature as “trans...

    Authors: Elie Haddad, Carmen Joukhadar, Nabil Chehata, Roy Nasnas and Jacques Choucair
    Citation: BMC Infectious Diseases 2015 15:182
    Content type: Case report Published on:

  29. The incidence of M. tuberculosis (MTB) and non tuberculous Mycobacterium species (NTMs) like M. avium and M. kansasii has increased due to Human Immunodeficiency Virus (HIV) epidemic. Therefore accurate, rapid an...

    Authors: Arnold Bainomugisa, Eddie Wampande, Chris Muchwa, Joseph Akol, Paul Mubiri, Henry Ssenyungule, Enock Matovu, Sam Ogwang and Moses Joloba
    Citation: BMC Infectious Diseases 2015 15:181
    Content type: Research article Published on:

  30. Hepatitis B (HB) infection is common in Mali. However, there is little information on molecular and biochemical characteristics of HB carriers.

    Authors: Fatou Traoré, Emmanuelle Gormally, Stéphanie Villar, Marlin D Friesen, John D Groopman, Guy Vernet, Souleymane Diallo, Pierre Hainaut and Moussa Y Maiga
    Citation: BMC Infectious Diseases 2015 15:180
    Content type: Research article Published on:

  31. Imipenem-resistant Acinetobacter baumannii (IRAB) is an important cause of hospital-acquired infection. We aimed to describe an outbreak of IRAB infection and to investigate its possible source in an intensive ca...

    Authors: Dan Ye, Jinglan Shan, Yongbo Huang, Jianchun Li, Changan Li, Xiaoqing Liu, Weiqun He, Yimin Li and Pu Mao
    Citation: BMC Infectious Diseases 2015 15:179
    Content type: Research article Published on:

  32. We explored the impact of transient cART started during the primary HIV-infection (PHI) on the long-term immunologic and virologic response on cART resumption, by comparison with treatment initiation during th...

    Authors: Evguenia Krastinova, Remonie Seng, Jerome Lechenadec, Henri Panjo, Asma Essat, Djamila Makhloufi, Martine Obadia, Louis Bernard, Cecile Goujard and Laurence Meyer
    Citation: BMC Infectious Diseases 2015 15:178
    Content type: Research article Published on:

  33. To investigate clinical features of infectious endophthalmitis over five years in a South Korean population.

    Authors: Ki Yup Nam, Joo Eun Lee, Ji Eun Lee, Woo Jin Jeung, Jung Min Park, Jong Moon Park, In Young Chung, Yong Seop Han, Il Han Yun, Hyun Wong Kim, Ik Soo Byon, Boo Sup Oum, Hee Sung Yoon, Dong Park, Byeng Chul Yu, Eun-Kee Park…
    Citation: BMC Infectious Diseases 2015 15:177
    Content type: Research article Published on:

  34. The causes of severe morbidity in health facilities implementing Antiretroviral Treatment (ART) programmes are poorly documented in sub-Saharan Africa. We aimed to describe severe morbidity among HIV-infected ...

    Authors: Yao Abo, Marcel Zannou Djimon, Eugène Messou, Eric Balestre, Martial Kouakou, Jocelyn Akakpo, Carin Ahouada, Nathalie de Rekeneire, François Dabis, Charlotte Lewden and Albert Minga
    Citation: BMC Infectious Diseases 2015 15:176
    Content type: Research article Published on:

  35. In the Mitra plus study of prevention of mother-to-child transmission of HIV-1, which included 501 women in Dar es Salaam, Tanzania, triple antiretroviral therapy (ART) was given from late pregnancy throughout...

    Authors: Matilda Ngarina, Charles Kilewo, Katarina Karlsson, Said Aboud, Annika Karlsson, Gaetano Marrone, Germana Leyna, Anna Mia Ekström and Gunnel Biberfeld
    Citation: BMC Infectious Diseases 2015 15:175
    Content type: Research article Published on:

  36. The advent of next-generation sequencing (NGS) has revolutionised public health microbiology. Given the potential impact of NGS, it is paramount to ensure standardisation of ‘wet’ laboratory and bioinformatic ...

    Authors: Jacob Moran-Gilad, Vitali Sintchenko, Susanne Karlsmose Pedersen, William J Wolfgang, James Pettengill, Errol Strain and Rene S Hendriksen
    Citation: BMC Infectious Diseases 2015 15:174
    Content type: Correspondence Published on:

  38. Toxoplasma gondii infection has been associated with psychiatric diseases. However, there is no information about the link between this infection and patients with mental and behavioral disorders due to psychoact...

    Authors: Cosme Alvarado-Esquivel, David Carrillo-Oropeza, Sandy Janet Pacheco-Vega, Jesús Hernández-Tinoco, Misael Salcedo-Jaquez, Luis Francisco Sánchez-Anguiano, María Nalleli Ortiz-Jurado, Yesenia Alarcón-Alvarado, Oliver Liesenfeld and Isabel Beristain-García
    Citation: BMC Infectious Diseases 2015 15:172
    Content type: Research article Published on:

  39. The risk of life-threatening and invasive infections with encapsulated bacteria is increased in patients with hyposplenia or asplenia. We report a case of recurrent invasive pneumococcal meningitis in a woman ...

    Authors: Vibe C Ballegaard, Lone Schejbel, Steen Hoffmann, Bjørn Kantsø and Christian P Fischer
    Citation: BMC Infectious Diseases 2015 15:171
    Content type: Case report Published on:

  40. The objective of this study was to explore effects of khat (Catha edulis) on outcome of rodent malaria infection and its anti-plasmodial activities on Plasmodium berghei ANKA (PbA).

    Authors: Tsige Ketema, Moti Yohannes, Esayas Alemayehu and Argaw Ambelu
    Citation: BMC Infectious Diseases 2015 15:170
    Content type: Research article Published on:

  41. Our aim was to determine and characterize S. aureus (SA) isolated from infections in newborns for antibiotic resistance, virulence factors, genotypes, epidemiology and antibiotic consumption.

    Authors: Dorota Romaniszyn, Anna Różańska, Jadwiga Wójkowska-Mach, Agnieszka Chmielarczyk, Monika Pobiega, Paweł Adamski, Ewa Helwich, Ryszard Lauterbach, Maria Borszewska-Kornacka, Ewa Gulczyńska, Agnieszka Kordek and Małgorzata Bulanda
    Citation: BMC Infectious Diseases 2015 15:169
    Content type: Research article Published on:

  42. This study examined colonisation with and characteristics of antimicrobial-resistant organisms among residents of a long-term care facility (LTCF) over one year, including strain persistence and molecular dive...

    Authors: Catherine Ludden, Martin Cormican, Akke Vellinga, James R Johnson, Bernie Austin and Dearbháile Morris
    Citation: BMC Infectious Diseases 2015 15:168
    Content type: Research article Published on:

  43. Dengue is endemic to the tropics and subtropics, and the most frequent of arthropod-borne viral diseases. Reliable diagnosis of dengue infection is important not only in clinical care but also in disease surve...

    Authors: Cristina Domingo, María Joao Alves, Fernando de Ory, Anette Teichmann, Herbert Schmitz, Rolf Müller and Matthias Niedrig
    Citation: BMC Infectious Diseases 2015 15:167
    Content type: Research article Published on:

  44. The performance of recommended control measures is necessary for quick and uniform infectious disease outbreak control. To assess whether these procedures are performed, a valid set of quality indicators (QIs)...

    Authors: Evelien Belfroid, Jeannine LA Hautvast, Mirrian Hilbink, Aura Timen and Marlies EJL Hulscher
    Citation: BMC Infectious Diseases 2015 15:166
    Content type: Research article Published on:

  45. Nearly one third of the world is infected with latent tuberculosis infection (LTBI) and a vast pool of individuals with LTBI persists in developing countries, posing a major barrier to global TB control. The a...

    Authors: Florence N Kizza, Justin List, Allan K Nkwata, Alphonse Okwera, Amara E Ezeamama, Christopher C Whalen and Juliet N Sekandi
    Citation: BMC Infectious Diseases 2015 15:165
    Content type: Research article Published on:

  46. A worldwide poliomyelitis eradication program was initiated in 1988; however, strains of wild poliovirus (WPV) are still endemic in some countries. Until WPV transmission is eradicated globally, importation an...

    Authors: Hye-Jin Kim, Seoyeon Hwang, Somin Lee, Yunhyung Kwon, Kwangsook Park, Young Joon Park, Geun-Ryang Bae, Sang Won Lee, Yong-Seok Jeong and Ji-Yeon Hyeon
    Citation: BMC Infectious Diseases 2015 15:164
    Content type: Research article Published on:

  47. In May 2005, a long-distance outbreak of Legionnaires’ disease (LD) caused by Legionella pneumophila serogroup 1 occurred in south-east Norway. The initial outbreak investigation without serology identified 56 la...

    Authors: Øystein Simonsen, Elisabeth Wedege, Anita Kanestrøm, Karin Bolstad, Ingeborg S Aaberge, Eivind Ragnhildstveit and Jetmund Ringstad
    Citation: BMC Infectious Diseases 2015 15:163
    Content type: Research article Published on:

  48. Tamiflu (oseltamivir phosphate ester, OE) is a widely used antiviral active against influenza A virus. Its active metabolite, oseltamivir carboxylate (OC), is chemically stable and secreted into wastewater tre...

    Authors: Peter Norberg, Magnus Lindh and Sigvard Olofsson
    Citation: BMC Infectious Diseases 2015 15:162
    Content type: Research article Published on:

  49. Klebsiella pneumoniae has been the dominant pathogen for liver abscesses in several Asian countries. Although the prevalence of K. pneumoniae liver abscess (KLA) in mainland China is increasing recently, the clin...

    Authors: Ting-ting Qu, Jian-cang Zhou, Yan Jiang, Ke-ren Shi, Bin Li, Ping Shen, Ze-qing Wei and Yun-song Yu
    Citation: BMC Infectious Diseases 2015 15:161
    Content type: Research article Published on:

  50. Cervical cancer is the most common cancer among women of reproductive age in Thailand. However, information on the prevalence and correlates of anogenital HPV infection in Thailand is sparse.

    Authors: Morgan A Marks, Swati Gupta, Kai-Li Liaw, Amha Tadesse, Esther Kim, Chailert Phongnarisorn, Virach Wootipoom, Pissamai Yuenyao, Charoen Vipupinyo, Sungwal Rugpao, Somchai Sriplienchan, Patti E Gravitt and David D Celentano
    Citation: BMC Infectious Diseases 2015 15:159
    Content type: Research article Published on:

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