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  1. Molecular resistance detection (MRD) of resistance to second-line anti-tuberculous drugs provides faster results than phenotypic tests, may shorten treatment and allow earlier separation among patients with an...

    Authors: AH van’t Hoog, I. Bergval, N. Tukvadze, S. Sengstake, R. Aspindzelashvili, RM Anthony and F. Cobelens
    Citation: BMC Infectious Diseases 2015 15:473
  2. Candidaemia and other forms of invasive candidiasis (C/IC) in the intensive care unit are challenging conditions that are associated with high rates of mortality. New guidelines from the European Society for C...

    Authors: Georg Auzinger, E. Geoffrey Playford, Christopher N. Graham, Hediyyih N. Knox, David Weinstein, Michal Kantecki, Haran Schlamm and Claudie Charbonneau
    Citation: BMC Infectious Diseases 2015 15:463
  3. Both cervical cancer and human immunodeficiency virus (HIV) are major public health problems in Sub-Saharan Africa. The objectives of the study were to investigate human papillomavirus (HPV) prevalence accordi...

    Authors: Zizipho Z A Mbulawa, David Coetzee and Anna-Lise Williamson
    Citation: BMC Infectious Diseases 2015 15:459
  4. In our study, we investigated whether circulating T follicular helper (Tfh) and the related cytokines are involved in human cystic echinococcosis (CE).

    Authors: Fengbo Zhang, Nannan Pang, Yuejie Zhu, Dexian Zhou, Hui Zhao, Jinwei Hu, Xiumin Ma, Jun Li, Hao Wen, Buka Samten, Haining Fan and Jianbing Ding
    Citation: BMC Infectious Diseases 2015 15:457
  5. In conjunction with the spread of HIV infection, tuberculosis (TB) remains a major cause of illness and death worldwide. The Ethiopian national report reveals that extra pulmonary tuberculosis is on the rise a...

    Authors: Workneh Korma, Adane Mihret, Jemal Hussien, Richard Anthony, Mekuria Lakew and Abraham Aseffa
    Citation: BMC Infectious Diseases 2015 15:456
  6. Skin and soft tissue infections (SSTIs) are common in the era of community-associated methicillin resistant Staphylococcus aureus among HIV-infected patients. Recurrent infections are frequent. Risk factors for r...

    Authors: Vagish Hemmige, Moira McNulty, Ethan Silverman and Michael Z. David
    Citation: BMC Infectious Diseases 2015 15:455
  7. Artemisinin-based combination treatments (ACTs) or intravenous artesunate are used in over 100 countries for uncomplicated or severe falciparum malaria. Although intravenous artesunate may cause delayed haemol...

    Authors: Akintunde Sowunmi, Kazeem Akano, Adejumoke I. Ayede, Godwin Ntadom, Bayo Fatunmbi, Temitope Aderoyeje and Elsie O. Adewoye
    Citation: BMC Infectious Diseases 2015 15:454
  8. As the average age of the HIV-positive population increases, there is increasing need to monitor patients for the development of comorbidities as well as for drug toxicities.

    Authors: Jennifer Gillis, Ahmed M Bayoumi, Ann N Burchell, Curtis Cooper, Marina B Klein, Mona Loutfy, Nima Machouf, Julio SG Montaner, Chris Tsoukas, Robert S Hogg and Janet Raboud
    Citation: BMC Infectious Diseases 2015 15:453
  9. The use of molecular diagnostic techniques for the evaluation of the impact of pneumococcal conjugate vaccines (PCVs) has not been documented. We aimed to evaluate the impact of PCVs on invasive pneumococcal d...

    Authors: Stefano Tempia, Nicole Wolter, Cheryl Cohen, Sibongile Walaza, Claire von Mollendorf, Adam L. Cohen, Jocelyn Moyes, Linda de Gouveia, Susan Nzenze, Florette Treurnicht, Marietjie Venter, Michelle J. Groome, Shabir A. Madhi and Anne von Gottberg
    Citation: BMC Infectious Diseases 2015 15:450
  10. The most common cause of Gram-negative bacterial neonatal meningitis is E. coli K1. It has a mortality rate of 10–15 %, and neurological sequelae in 30–50 % of cases. Infections can be attributable to nosocomial ...

    Authors: Aldukali Alkeskas, Pauline Ogrodzki, Mohamed Saad, Naqash Masood, Nasreddin R. Rhoma, Karen Moore, Audrey Farbos, Konrad Paszkiewicz and Stephen Forsythe
    Citation: BMC Infectious Diseases 2015 15:449
  11. Toxoplasma gondii can infect almost all warm-blood animals including human beings. The high incidence and severe damage that can be caused by T. gondii infection clearly indicates the need for the development of ...

    Authors: Shuai Wang, YuJian Wang, XiaoNi Sun, ZhenChao Zhang, TingQi Liu, Javaid Ali Gadahi, Ibrahim Adam Hassan, LiXin Xu, RuoFeng Yan, XiaoKai Song and XiangRui Li
    Citation: BMC Infectious Diseases 2015 15:448
  12. Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.

    Authors: Débora Natalia Marcone, Lizette O. Durand, Eduardo Azziz-Baumgartner, Santiago Vidaurreta, Jorge Ekstrom, Guadalupe Carballal and Marcela Echavarria
    Citation: BMC Infectious Diseases 2015 15:447
  13. Rotavirus is the most common cause of severe gastroenteritis in children under the age of 5 years worldwide. It is well recognised that rotavirus can cause signs and symptoms beyond the gastrointestinal tract,...

    Authors: Konstantinos Karampatsas, Christina Spyridou, Ian R. Morrison, Cheuk Y. W. Tong and Andrew J. Prendergast
    Citation: BMC Infectious Diseases 2015 15:446
  14. Visceral leishmaniasis (VL), i.e., infection with Leishmania sp. associated with high fever, weight loss, massive splenomegaly and markedly altered laboratory parameters, is generally fatal if untreated. The poss...

    Authors: Oussama Mouri, Mathilde Benhamou, Gaëlle Leroux, Nathalie Chartrel, Alain Devidas, Marc Thellier, Zahir Amoura, Nathalie Costedoat-Chalumeau and Pierre Buffet
    Citation: BMC Infectious Diseases 2015 15:445
  15. Staphylococcus aureus is one of most common pathogens in humans. Methicillin-resistant S. aureus (MRSA) accounts for 64 % of S. aureus bacteremia isolated in intensive care units (ICUs), and heteroresistant vanco...

    Authors: Han-Chung Hu, Kuo-Chin Kao, Li-Chung Chiu, Chih-Hao Chang, Chen-Yiu Hung, Li-Fu Li, Tsui-Ping Liu, Lee-Chung Lin, Ning-Hung Chen, Chung-Chi Huang, Cheng-Ta Yang and Jang-Jih Lu
    Citation: BMC Infectious Diseases 2015 15:444
  16. Growing evidence suggests respiratory syncytial virus (RSV) is an important cause of respiratory disease in adults. However, the adult burden remains largely uncharacterized as most RSV studies focus on childr...

    Authors: Douglas M. Fleming, Robert J. Taylor, Roger L. Lustig, Cynthia Schuck-Paim, François Haguinet, David J Webb, John Logie, Gonçalo Matias and Sylvia Taylor
    Citation: BMC Infectious Diseases 2015 15:443
  17. Nosocomial infections are the most common complication during inpatient hospital care. An increasing proportion of these infections are caused by multidrug-resistant organisms (MDROs). This report describes an...

    Authors: Miriam G. Gerlich, Jens Piegsa, Christian Schäfer, Nils-Olaf Hübner, Florian Wilke, Susanne Reuter, Georg Engel, Ralf Ewert, Franziska Claus, Claudia Hübner, Walter Ried, Steffen Flessa, Axel Kramer and Wolfgang Hoffmann
    Citation: BMC Infectious Diseases 2015 15:441
  18. In Germany, 17 % of the general human population have antibodies to hepatitis E virus (HEV) (recomLine HEV-IgG/IgM immunoassay [Mikrogen GmbH]). Wild boars represent an animal reservoir for HEV genotype 3, whi...

    Authors: A. Schielke, V. Ibrahim, I. Czogiel, M. Faber, C. Schrader, P. Dremsek, R. G. Ulrich and R. Johne
    Citation: BMC Infectious Diseases 2015 15:440
  19. Pregnant women in malaria endemic areas are at high risk of P. falciparum infection and its complications. This study investigated the prevalence and risk factors for P. falciparum infection and malaria among pre...

    Authors: Judith K. Anchang-Kimbi, Vera Ngenwie Nkweti, Helen Ngum Ntonifor, Tobias O. Apinjoh, Rolland Bantar Tata, Hanesh Fru Chi and Eric Akum Achidi
    Citation: BMC Infectious Diseases 2015 15:439
  20. With the renewed emphasis to implement isoniazid preventive therapy (IPT) in Sub-Saharan Africa, we investigated the effect of IPT on immunological profiles among household contacts with latent tuberculosis.

    Authors: Irene Andia Biraro, Moses Egesa, Simon Kimuda, Steven G. Smith, Frederic Toulza, Jonathan Levin, Moses Joloba, Achilles Katamba, Stephen Cose, Hazel M. Dockrell and Alison M Elliott
    Citation: BMC Infectious Diseases 2015 15:438
  21. It has been widely acknowledged that well-planned and executed communication programmes can contribute to achieving malaria prevention and treatment goals. This however requires a good understanding of current...

    Authors: Jane C Umeano-Enemuoh, Benjamim Uzochukwu, Nkoli Ezumah, Lindsay Mangham-Jefferies, Virginia Wiseman and Obinna Onwujekwe
    Citation: BMC Infectious Diseases 2015 15:437
  22. A birth cohort dedicated to studying infections in early childhood may be assisted by parental recording of symptoms on a daily basis and a collection of biomaterials. We aimed at testing the feasibility of th...

    Authors: Beate Zoch, André Karch, Johannes Dreesman, Masyar Monazahian, Armin Baillot and Rafael T. Mikolajczyk
    Citation: BMC Infectious Diseases 2015 15:436
  23. The number of catheter related bloodstream infections (CRBSI) could be reduced and the outcome improved if specific standards in the quality of care were maintained. Therefore, the development of quality assur...

    Authors: Anke Bramesfeld, Stephanie Wrede, Klaus Richter, Mareike Steen, Björn Broge, Jürgen Pauletzki and Joachim Szecsenyi
    Citation: BMC Infectious Diseases 2015 15:435
  24. Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about the ...

    Authors: Edana Cassol, Theresa Rossouw, Susan Malfeld, Phetole Mahasha, Tomas Slavik, Chris Seebregts, Robert Bond, Johannie du Plessis, Carl Janssen, Tania Roskams, Frederik Nevens, Massimo Alfano, Guido Poli and Schalk W. van der Merwe
    Citation: BMC Infectious Diseases 2015 15:430
  25. Evidence on influenza vaccine effectiveness (VE) is commonly derived from observational studies. However, these studies are prone to confounding by indication and healthy vaccinee bias. We aimed to systematica...

    Authors: Cornelius Remschmidt, Ole Wichmann and Thomas Harder
    Citation: BMC Infectious Diseases 2015 15:429
  26. In the current Ebola epidemic in Western Africa, many healthcare workers have become infected. Some of these have been medically evacuated to hospitals in Europe and the USA. These clinical experiences provide...

    Authors: Nicola Petrosillo, Emanuele Nicastri, Simone Lanini, Maria Rosaria Capobianchi, Antonino Di Caro, Mario Antonini, Vincenzo Puro, Francesco Nicola Lauria, Nakono Shindo, Nicola Magrini, Gary P. Kobinger and Giuseppe Ippolito
    Citation: BMC Infectious Diseases 2015 15:432
  27. Hepatitis A is still a neglected health problem in the world. The most affected areas are the ones with disadvantaged socioeconomic conditions. In Brazil, seroprevalence studies showed that 64.7 % of the gener...

    Authors: Saulo A. S. Mantovani, Breno Matos Delfino, Antonio C. Martins, Humberto Oliart-Guzmán, Thasciany M. Pereira, Fernando L. C. C. Branco, Athos Muniz Braña, José A. Filgueira-Júnior, Ana P. Santos, Rayanne A. Arruda, Andréia S. Guimarães, Alanderson A. Ramalho, Cristieli Sergio de Menezes Oliveira, Thiago S. Araújo, Nancy Arróspide, Carlos H. M. L. Estrada…
    Citation: BMC Infectious Diseases 2015 15:428
  28. Enterococcus spp. are particularly important etiological agents of nosocomial infections. However, the clinical characteristics of and risk factors for enterococcal infections in clinical settings are poorly unde...

    Authors: Toshiki Kajihara, Shigeki Nakamura, Naoki Iwanaga, Kazuhiro Oshima, Takahiro Takazono, Taiga Miyazaki, Koichi Izumikawa, Katsunori Yanagihara, Nobuoki Kohno and Shigeru Kohno
    Citation: BMC Infectious Diseases 2015 15:426
  29. The objective of this study was to explore the prevalence of microbiological contamination of mobile phones that belong to clinicians in intensive care units (ICUs), pediatric intensive care units (PICUs), and...

    Authors: Mohammed Heyba, Mohammad Ismaiel, Abdulrahman Alotaibi, Mohamed Mahmoud, Hussain Baqer, Ali Safar, Noura Al-Sweih and Abdullah Al-Taiar
    Citation: BMC Infectious Diseases 2015 15:434
  30. Acinetobacter baumannii strains co-producing carbapenemase and 16S rRNA methylase are highly resistant to carbapenems and aminoglycosides.

    Authors: Tatsuya Tada, Tohru Miyoshi-Akiyama, Kayo Shimada, Tran Thi Thanh Nga, Le Thi Anh Thu, Nguyen Truong Son, Norio Ohmagari and Teruo Kirikae
    Citation: BMC Infectious Diseases 2015 15:433
  31. This study was designed to explore the epidemiological and clinical profiles of respiratory syncytial virus (RSV) infection in neonates from the Suzhou area of China, taking into consideration how climate fact...

    Authors: Lianghua Lu, Yongdong Yan, Bin Yang, Zhihui Xiao, Xing Feng, Yuqing Wang, Wei Ji, Maximillion Mize, Chuangli Hao and Zhengrong Chen
    Citation: BMC Infectious Diseases 2015 15:431
  32. The primary influenza prevention strategy is focused on annual vaccination according to the categories identified in the various countries as being at greatest risk of complications. Many studies were conducte...

    Authors: Claudia Pileggi, Francesca Lotito, Aida Bianco, Carmelo G. A. Nobile and Maria Pavia
    Citation: BMC Infectious Diseases 2015 15:427
  33. Noroviruses (NoVs) are the most common cause of acute gastroenteritis (AGE) causing both sporadic and outbreak-associated illness. Norovirus (NoV) infections occur across all ages but certain sub-groups are co...

    Authors: Lisa Lindsay, Joanne Wolter, Ilse De Coster, Pierre Van Damme and Thomas Verstraeten
    Citation: BMC Infectious Diseases 2015 15:425
  34. Salmonella enterica, serovar Typhi (S. Typhi), a causative agent of enteric fever (typhoid fever), predominately affects populations in developing regions with poor access to clean food and water. In addition, tr...

    Authors: Tia Sorrell, Daniel J. Selig, Mark S. Riddle and Chad K. Porter
    Citation: BMC Infectious Diseases 2015 15:424
  35. Sustaining high uptake of praziquantel is key for long-term control of schistosomiasis. During mass treatment in 2013, we randomized 12 primary schools into two groups; one group received education messages fo...

    Authors: Simon Muhumuza, Annette Olsen, Anne Katahoire and Fred Nuwaha
    Citation: BMC Infectious Diseases 2015 15:423
  36. Chronic kidney disease, including end-stage renal disease, has been identified as a possible risk factor for primary septicemia and wound infection by Vibrio vulnificus. However, cases of severe septicemia, necro...

    Authors: Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma and Soo Wan Kim
    Citation: BMC Infectious Diseases 2015 15:422
  37. Traditional cardiovascular disease (CVD) risk factors contribute to increase risk of CVD in people living with HIV (PLWH). Of all world regions, sub-Saharan Africa has the highest prevalence of HIV yet little ...

    Authors: Tecla M. Temu, Nicholas Kirui, Celestine Wanjalla, Alfred M. Ndungu, Jemima H. Kamano, Thomas S. Inui and Gerald S. Bloomfield
    Citation: BMC Infectious Diseases 2015 15:421
  38. Dengue is the most common mosquito-borne viral disease in humans. Recently, there has been an epidemic shift of dengue from mainly affecting children to affecting more adults with increased severity. However, ...

    Authors: Vipa Thanachartwet, Nittha Oer-areemitr, Supat Chamnanchanunt, Duangjai Sahassananda, Akanitt Jittmittraphap, Plengsakoon Suwannakudt, Varunee Desakorn and Anan Wattanathum
    Citation: BMC Infectious Diseases 2015 15:420
  39. Pneumococcal diseases remain a leading cause of vaccine-preventable death worldwide in children <5 years of age. The seven-valent pneumococcal conjugate vaccine (PCV7) was approved in 2001 in Europe and was in...

    Authors: Myint Tin Tin Htar, Dina Christopoulou and Heinz-Josef Schmitt
    Citation: BMC Infectious Diseases 2015 15:419
  40. Rotavirus (RV) vaccine was added to Yemen’s childhood vaccination schedule in late 2012. We evaluated the effect of vaccination on the epidemiology of acute gastroenteritis (AGE) and the characteristics of cir...

    Authors: Salem M. Banajeh and Basheer A. Abu-Asba
    Citation: BMC Infectious Diseases 2015 15:418
  41. Necrotizing fasciitis (NF) is a rapidly progressive and life-threatening infection. This study aimed to investigate the clinical characteristics and mortality- associated factors in diabetic patients.

    Authors: Nai-Chen Cheng, Hao-Chih Tai, Shan-Chwen Chang, Chin-Hao Chang and Hong-Shiee Lai
    Citation: BMC Infectious Diseases 2015 15:417
  42. Anecdotal evidence suggests that much of the continuing infection of health care workers (HCWs) with Ebola virus during the current outbreak in Sierra Leone has occurred in settings other than Ebola isolation ...

    Authors: Olushayo Olu, Brima Kargbo, Sarian Kamara, Alie H. Wurie, Jackson Amone, Louisa Ganda, Bernard Ntsama, Alain Poy, Fredson Kuti-George, Etsub Engedashet, Negusu Worku, Martin Cormican, Charles Okot, Zabulon Yoti, Kande-Bure Kamara, Kennedy Chitala…
    Citation: BMC Infectious Diseases 2015 15:416
  43. Bloodstream infections (BSI) due to carbapenem-resistant (C-R) Klebsiella pneumoniae (Kp) are of global concern from both clinical and public health standpoints. This retrospective study aimed to describe C-R Kp ...

    Authors: Cristiano Alicino, Daniele Roberto Giacobbe, Andrea Orsi, Federico Tassinari, Cecilia Trucchi, Giovanni Sarteschi, Francesco Copello, Valerio Del Bono, Claudio Viscoli and Giancarlo Icardi
    Citation: BMC Infectious Diseases 2015 15:415
  44. The rate of urinary tract infections (UTIs) due to extended-spectrum β-lactamase (ESBL)-producing bacterial strains requiring carbapenem therapy has been increasing in children. This study was conducted to eva...

    Authors: Seung Beom Han, Sung Chul Lee, Soo Young Lee, Dae Chul Jeong and Jin Han Kang
    Citation: BMC Infectious Diseases 2015 15:414
  45. There has been increasing debate surrounding mask and respirator interventions to control respiratory infection transmission in both healthcare and community settings. As decision makers are considering the re...

    Authors: Shohini Mukerji, C. Raina MacIntyre and Anthony T. Newall
    Citation: BMC Infectious Diseases 2015 15:413
  46. Gonococcal antimicrobial resistance is a global problem. Different resistance plasmids have emerged and spread among the isolates of Neisseria gonorrhoeae worldwide and in China. We conducted this study to monito...

    Authors: Heping Zheng, Xingzhong Wu, Jinmei Huang, Xiaolin Qin, Yaohua Xue, Weiying Zeng, Yinyuan Lan, Jiangli Ou, Sanmei Tang and Mingheng Fang
    Citation: BMC Infectious Diseases 2015 15:412
  47. Many people have multiple infections at the same time, but the combined contribution of those infections to disease-related mortality is unknown. Registered causes of death offer a unique opportunity to study ...

    Authors: E. C. Griffiths, A. B. Pedersen, A. Fenton and O. L. Petchey
    Citation: BMC Infectious Diseases 2015 15:411
  48. Febrile illness with suspected blood stream infection (BSI) is a common reason for admission to hospital in Africa and blood cultures are therefore an important investigation. Data on the prevalence and causes...

    Authors: Tom H. Boyles, Kelly Davis, Thomas Crede, Jacques Malan, Marc Mendelson and Maia Lesosky
    Citation: BMC Infectious Diseases 2015 15:410
  49. Long-term protection against meningococcal disease is associated with persistence of post-vaccination antibodies at protective levels. We evaluated the bactericidal antibody persistence and safety of the quadr...

    Authors: Charissa Fay Corazon Borja-Tabora, Cecilia Montalban, Ziad A. Memish, Dominique Boutriau, Devayani Kolhe, Jacqueline M. Miller and Marie Van der Wielen
    Citation: BMC Infectious Diseases 2015 15:409

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