World Health Organization. The use of Antimalarial drugs. Report of a WHO informal consultation. Document WHO/CDS/RBM/2001.33. Geneva: WHO; 2001.
Google Scholar
World Health Organization. Antimalarial drugs combination therapy. Report of a WHO technical consultation. Document WHO/CDS/RBM/2001.35. Geneva: WHO; 2001.
Google Scholar
White NJ. Qinghaosu (artemisinin): the price of success. Science. 2008;320:330–4.
Article
CAS
PubMed
Google Scholar
Bosman A, Mendis KN. A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies. Am J Trop Med Hyg. 2007;77 Suppl 6:193–7.
PubMed
Google Scholar
Dondorp A, Nosten F, Stepniewska K, Day N, White N. Artemisinin versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet. 2005;366:717–25.
Article
PubMed
Google Scholar
Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A, Chhaganlal KD, et al. Artesunate versus quinine in the treatment of severe malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet. 2010;376:1647–57.
Article
CAS
PubMed
PubMed Central
Google Scholar
World Health Organization. Guidelines for the Treatment of Malaria. 2nd ed. Geneva, Switzerland: World Health Organization; 2010.
Google Scholar
Zoller T, Junghanss T, Kapaun A, Gjørup I, Richter J, Hugo-Persson M, et al. Intravenous artesunate for severe malaria in travelers, Europe. Emerging Inf Dis. 2011;17:771–7.
Article
Google Scholar
Kreeftmeijer-Vetger AR, Genderen PJ, Visser LG, Bierman WFW, Clerinx J, van Veldehuizen CKW, et al. Treatment outcome of intravenous artesunate in patients with severe malaria in Netherlands and Belgium. Malaria J. 2012;11:102–12.
Article
Google Scholar
World Health Organization. WHO Information Note on Delayed Haemolytic Anaemia Following Treatment with Artesunate. Geneva, Switzerland: WHO; 2013.
Google Scholar
Medicine for Malaria Venture: Experts Group Meeting on Delayed Haemolytic Anaemia Following Treatment with Injectable Artesunate. Vienna, Austria, 2013. (http:/www.mmv.org/newsroom/events/expert-group-meeting-safety-profile-injectable-artesunate).
Price RC, Simpson JA, Nosten F, Luxemberger C, Hkirjaroen L, ter Kuile F, et al. Factors contributing to anemia after uncomplicated falciparum malaria. Am J Trop Med Hyg. 2001;65:614–22.
CAS
PubMed
PubMed Central
Google Scholar
Sowunmi A, Gbotosho GO, Happi CT, Fateye BA. Factors contributing to anaemia after uncomplicated Plasmodium falciparum malaria in children. Acta Trop. 2010;133:155–61.
Article
Google Scholar
Ouedraogo HZ, Zeba A, Dramaix-Wilmet M, Donnen P. Moderate to severe anaemia due to afebrile Plasmodium falciparum infections in children aged 6–23 months from rural district of Kongoussi, Burkina Faso. J Trop Pediatr. 2008;54:395–400.
Article
PubMed
Google Scholar
Sumbele IUN, Samje M, Nkuo-Akenji T. A longitudinal study on anaemia in children with Plasmodium falciparum infection in the Mount Cameroon region: prevalence, risk factors and perceptions by caregivers. BMC Infect Dis. 2013;13:123.
Article
PubMed
PubMed Central
Google Scholar
Biemba G, Gorduek VR, Thuma P, Weiss G. Markers of inflammation in children with severe malaria. Trop Med Int Health. 2000;5:256–62.
Article
CAS
Google Scholar
Helleberg M, Goka BQ, Akanmori BD, Obeng-Adjei G, Rodriques O, Kurtzhals JAL. Bone marrow suppression and severe anaemia associated with persistent Plasmodium falciparum infection in African children with microscopically undetectable parasitaemia. Malaria J. 2005;4:56.
Article
Google Scholar
Awah NW, Troye-Blomberg M, Berzins K, Gysin J. Mechanisms of malarial anaemia: potential involvement of Plasmodium falciparum low molecular weight rhoptry-associated proteins. Acta Trop. 2009;112:299–302.
Article
Google Scholar
Premji Z, Umeh RE, Uwusu-Agyei S, Fabian E, Ezedinachi EU, Oguche S, et al. Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria. PLoS One. 2009;4, e6682.
Article
PubMed
PubMed Central
Google Scholar
Gbotosho GO, Sowunmi A, Okuboyejo TM, Happi CT, Folarin OO, Michael SO, et al. Therapeutic efficacy and effect of artemether-lumefantrine and artesunate-amodiaquine cofomulated or copackaged on malaria-associated anemia in children in uncomplicated Plasmodium falciparum malaria in southwest Nigeria. Am J Trop Med Hyg. 2011;84:813–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Oguche S, Okafor HU, Watila I, Meremikwu M, Agomo P, Ogala W, et al. Efficacy of artemisinin-based combination treatments of uncomplicated falciparum malaria in under-five year-old Nigerian children. Am J Trop Med Hyg. 2014;91:925–35.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gbotosho GO, Sowunmi A, Okuboyejo TM, Happi CT, Folarin OO, Adewoye EO. A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated malaria in children: Comparison of therapeutic efficacy with standard dose regimen of artesunate-lumefantrine. Am J Therap. 2011;19, e122.
Article
Google Scholar
Sowunmi A, Akinrinola AA, Gbotosho GO, Okuboyejo TM, Happi CT. A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: A preliminary evaluation. J Trop Ped. 2012;58:263–8.
Article
Google Scholar
World Health Organization. Severe falciparum malaria. Trans R Soc Trop Med Hyg. 2000;94 Suppl 1:1–90.
Article
Google Scholar
Sowunmi A, Balogun ST, Gbotosho GO, Happi CT. Effects of amodiaquine, artesunate, and artesunate-amodiaquine of Plasmodium falciparum malaria-associated anaemia in children. Acta Trop. 2009;109:55–60.
Article
CAS
PubMed
Google Scholar
Sowunmi A, Gbotosho GO, Happi CT, Folarin O, Okuboyejo T, Michael O, et al. Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anaemia after treatment. Am J Therap. 2011;18:1190–7.
Article
Google Scholar
Rowland M, Tozer TN. Clinical pharmacokinetics: concept and application. Philadelphia: Philadelphia PA Lea and Ferbiger; 1980. p. 288–91.
Google Scholar
Bain BJ, Bates I. Basic haematological techniques. In: Lewis SM, Bain BJ, Bates I, editors. Practical Haematology. 9th ed. Edinburgh: Churchill Living stone; 2001. p. 19–46.
Google Scholar
Epi Info Version 6. A Word Processing Data Base and Statistics Program for Public Health on IBM-compatible Microcomputers. Atlanta, GA: Centers for Disease Control and Prevention; 1994.
Google Scholar
SPSS for Windows Release 20.0 (standard version). SPSS Inc., Chicago IL; 2011.
Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;i:307–10.
Article
Google Scholar
Sowunmi A, Gbotosho GO, Happi C, Okuboyejo T, Folarin O, Balogun S, et al. Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria. Am J Trop Med Hyg. 2009;81:979–86.
Article
CAS
PubMed
Google Scholar
Fleming AF, Storey J, Molineaux L, Iroko EA, Attai ED. Abnormal haemoglobins in the Sudan savanna of Nigeria. I. Prevalence of haemoglobins and relationship between sickle cell trait, malaria and survival. Ann Trop Med Parasitol. 1979;73:161–72.
Article
CAS
PubMed
Google Scholar
Mockenhaupt FP, Falusi AG, May J, Ademowo OG, Olumese PE, Meyer CG, et al. The contribution of α-thalassaemia to anaemia in Nigeria population exposed to intense malaria transmission. Trop Med Int Health. 1999;4:302–7.
Article
CAS
PubMed
Google Scholar
Bienzle U. Glucose-6-phosphate dehydrogenase deficiency. Part 1: Tropical Africa. Clin Haematol. 1981;10:785–99.
CAS
PubMed
Google Scholar
Adewunmi CO, Gebremedhin G, Becker W, Olorunmola FO, Dorfler G, Adewunmi TA. Schistosomiasis and intestinal parasites in rural villages in southwest Nigeria: an indication for expanded programme on drug distribution and integrated control programme in Nigeria. Trop Med Parasitol. 1993;44:177–80.
CAS
PubMed
Google Scholar
White NJ, Ho M. The pathopysiology of malaria. In: Baker JR, Muller R, editors. Adv in Parasitol 1992. New York: Academic; 1992. p. 84–175.
Google Scholar
Jakeman GN, Saul A, Hogarith WL, Collins WE. Anaemia of acute malaria infection in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitol. 1999;119:127–33.
Article
Google Scholar
Menendez C, Fleming AF, Alonso PL. Malaria-related anaemia. Parasitol Today. 2000;16:469–76.
Article
CAS
PubMed
Google Scholar
Chotivanich K, Udomsangpetch R, Dondorp A, Williams T, Angus B, Simpson JA, et al. The mechanisms of parasite clearance after antimalarial treatment of Plasmodium falciparum malaria. J Infect Dis. 2000;182:629–33.
Article
CAS
PubMed
Google Scholar
Newton PN, Chotivanich K, Chierakul W, Ruagveerayuth R, Teerapong P, Silamut K, et al. A comparison of the in vivo kinetics of Plasmodium falciparum ring-infected erythrocyte surface antigen-positive and –negative erythrocytes. Blood. 2001;98:450–7.
Article
CAS
PubMed
Google Scholar
Angus BJ, Chotivanich K, Udomsangpetch White NJ. In vivo removal of malaria parasites from red blood cells without their destruction in acute falciparum malaria. Blood. 1997;2037–2040.
Gbotosho GO, Okuboyejo TM, Happi CT, Sowunmi A. Fall in haematocrit per 1000 parasites cleared from peripheral blood: a simple method for estimating drug-related fall in haematocrit after treatment of malaria infections. Am J Ther. 2014;21:193–7.
Article
PubMed
Google Scholar
Jauréguiberry S, Ndour PA, Roussel C, Ader F, Safeukui I, Nguyen M, et al. Postartesunate delayed hemolyssis is a predictable event related to the lifesaving effect of artemisinins. Blood. 2014;124:167–75.
Article
PubMed
PubMed Central
Google Scholar
Arguin PM. Case definition: postartemisinin delayed hemolysis. Blood. 2014;124:157–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rolling T, Agbenyega T, Issifou S, Adegnika J, Sylverken J, Spahlinger D, et al. Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria—a double-center prospective study. J Infect Dis. 2014;209:1921–8.
Article
CAS
PubMed
Google Scholar