Meyer DH, Fives-Taylor PM: The role of Actinobacillus actinomycetemcomitans in the pathogenesis of periodontal disease. Trends Microbiol. 1997, 15: 224-228. 10.1016/S0966-842X(97)01055-X.
Article
Google Scholar
Paju S, Carlson P, Jousimies-Somer H, Asikainen S: Heterogeneity of Actinobacillus actinomycetemcomitans strains in various human infections and relationships between serotype, genotype, and antimicrobial susceptibility. J Clin Microbiol. 2000, 38: 79-84.
CAS
PubMed
PubMed Central
Google Scholar
Paturel L, Casalta JP, Habib G, Nezri M, Raoult D: Actinobacillus actinomycetemcomitans endocarditis. Clin Microbiol Infect. 2004, 10: 98-118. 10.1111/j.1469-0691.2004.00794.x.
Article
CAS
PubMed
Google Scholar
Rottman M, Hanau-Bercot B, Fiszbin M, Raskine L, Gravisse J, Caulin C, Sanson-Le Pors MJ: Diagnosis of Actinobacillus actinomycetemcomitans infective endocarditis after steadily negative blood cultures. J Infect. 2002, 44: 208-210. 10.1053/jinf.2002.0967.
Article
PubMed
Google Scholar
Armitage GC: Development of a classification system for periodontal diseases and conditions. Ann Periodontol. 1999, 4: 1-6. 10.1902/annals.1999.4.1.1.
Article
CAS
PubMed
Google Scholar
Tinoco EM, Sivakumar M, Preus HR: The distribution and transmission of Actinobacillus actinomycetemcomitans in families with localized juvenile periodontitis. J Clin Periodontol. 1998, 25: 99-105. 10.1111/j.1600-051X.1998.tb02415.x.
Article
CAS
PubMed
Google Scholar
Zambon JJ: Actinobacillus actinomycetemcomitans in human periodontal disease. J Clin Periodontol. 1985, 12: 1-20. 10.1111/j.1600-051X.1985.tb01348.x.
Article
CAS
PubMed
Google Scholar
Kachlany SC, Fine DH, Figurski DH: Secretion of RTX leukotoxin by Actinobacillus actinomycetemcomitans. Infect Immun. 2000, 68: 6094-6100. 10.1128/IAI.68.11.6094-6100.2000.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kachlany SC, Fine DH, Figurski DH: Purification of secreted leukotoxin (LtxA) from Actinobacillus actinomycetemcomitans. Protein Expr Purif. 2002, 25: 465-467. 10.1016/S1046-5928(02)00037-2.
Article
CAS
PubMed
Google Scholar
Lally ET, Golub EE, Kieba IR, Taichman NS, Rosenbloom JJ, Rosenbloom CC, Gibson W, Demuth DR: Analysis of the Actinobacillus actinomycetemcomitans leukotoxin gene. Delineation of unique features and comparison to homologous toxins. J Biol Chem. 1989, 264: 15451-15456.
CAS
PubMed
Google Scholar
Lear JD, Karakelian D, Furblur U, Lally ET, Tanaka JC: Conformational studies of Actinobacillus actinomycetemcomitans leukotoxin: partial denaturation enhances toxicity. Biochim Biophys Acta. 2000, 1476: 350-362.
Article
CAS
PubMed
Google Scholar
Narayanan SK, Nagaraja TG, Chengappa MM, Stewart GC: Leukotoxins of gram-negative bacteria. Vet Microbiol. 2002, 84: 337-356. 10.1016/S0378-1135(01)00467-9.
Article
CAS
PubMed
Google Scholar
Yamaguchi N, Kubo C, Masuhiro Y, Lally ET, Koga T, Hanazawa S: Tumor necrosis factor alpha enhances Actinobacillus actinomycetemcomitans leukotoxin-induced HL-60 cell apoptosis by stimulating lymphocyte function-associated antigen 1 expression. Infect Immun. 2004, 72: 269-276. 10.1128/IAI.72.1.269-276.2004.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brogan JM, Lally ET, Poulsen K, Kilian MD: Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains. Infect Immun. 1994, 62: 501-508.
CAS
PubMed
PubMed Central
Google Scholar
Haraszthy VI, Hariharan G, Tinoco EM, Cortelli JR, Lally ET, Davis E, Zambon JJ: Evidence for the role of highly leukotoxic Actinobacillus actinomycetemcomitans in the pathogenesis of localized juvenile and other forms of early-onset periodontitis. J Periodontol. 2000, 71: 912-922. 10.1902/jop.2000.71.6.912.
Article
CAS
PubMed
Google Scholar
Haubek D, Westergaard J: Detection of a highly toxic clone of Actinobacillus actinomycetemcomitans (JP2) in a Moroccan immigrant family with multiple cases of localized aggressive periodontitis. Int J Paediatr Dent. 2004, 14: 41-48. 10.1111/j.1365-263X.2004.00518.x.
Article
CAS
PubMed
Google Scholar
Hritz M, Fisher E, Demuth DR: Differential regulation of the leukotoxin operon in highly leukotoxic and minimally leukotoxic strains of Actinobacillus actinomycetemcomitans. Infect Immun. 1996, 64: 2724-2729.
CAS
PubMed
PubMed Central
Google Scholar
Kolodrubetz D, Spitznagel J, Wang B, Phillips LH, Jacobs C, Kraig E: cis Elements and trans factors are both important in strain-specific regulation of the leukotoxin gene in Actinobacillus actinomycetemcomitans. Infect Immun. 1996, 64: 3451-3460.
CAS
PubMed
PubMed Central
Google Scholar
Holm A, Rabe P, Kalfas S, Edwarsson S: Improved selective culture media for Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus. J Clin Microbiol. 1987, 25: 1985-1988.
CAS
PubMed
PubMed Central
Google Scholar
Slots J: Selective medium for isolation of Actinobacillus actinomycetemcomitans. J Clin Microbiol. 1982, 15: 606-609.
CAS
PubMed
PubMed Central
Google Scholar
Doungudomdacha S, Rawlinson A, Douglas CW: Enumeration of Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans in subgingival plaque samples by a quantitative-competitive PCR method. J Med Microbiol. 2000, 49: 861-867.
Article
CAS
PubMed
Google Scholar
Komiya A, Kato T, Nakagawa T, Saito A, Takahashi J, Yamada S, Okuda KA: Rapid DNA probe method for detection of Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans. J Periodontol. 2000, 71: 760-767. 10.1902/jop.2000.71.5.760.
Article
CAS
PubMed
Google Scholar
Kuboniwa M, Amano A, Kimura KR, Sekine S, Kato S, Yamamoto Y, Okahashi N, Iida T, Shizukuishi S: Quantitative detection of parodontal pathogens using real-time polymerase chain reaction with TaqMan probes. Oral Microbiol Immunol. 2004, 19: 168-176. 10.1111/j.0902-0055.2004.00135.x.
Article
CAS
PubMed
Google Scholar
Lau L, Sanz M, Herrera D, Morillo JM, Martin C, Silva A: Quantitative real-time polymerase chain reaction versus culture: a comparison between two methods for the detection and quantification of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythensis in subgingival plaque samples. J Clin Periodontol. 2004, 31: 1061-1069. 10.1111/j.1600-051X.2004.00616.x.
Article
CAS
PubMed
Google Scholar
Leys EJ, Griffen AL, Strong SJ, Fuerst PA: Detection and strain identification of Actinobacillus actinomycetemcomitans by nested PCR. J Clin Microbiol. 1994, 32: 1288-1294.
CAS
PubMed
PubMed Central
Google Scholar
Maeda H, Fujimoto C, Haruki Y, Maeda T, Kokeguchi S, Petelin M, Arai H, Tanimoto I, Nishimura F, Takashiba S: Quantitative real-time PCR using TaqMan and SYBR Green for Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, tetQ gene and total bacteria. FEMS Immunol Med Microbiol. 2003, 39: 81-86. 10.1016/S0928-8244(03)00224-4.
Article
CAS
PubMed
Google Scholar
Morillo JM, Lau L, Sanz M, Herrera D, Silva A: Quantitative real-time PCR based on single copy gene sequence for detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. J Periodontal Res. 2003, 38: 518-524. 10.1034/j.1600-0765.2003.00684.x.
Article
CAS
PubMed
Google Scholar
Morillo JM, Lau L, Sanz M, Herrera D, Martin C, Silva A: Quantitative real-time polymerase chain reaction based on single copy gene sequence for detection of parodontal pathogens. J Clin Periodontol. 2004, 31: 1054-1060. 10.1111/j.1600-051x.2004.00608.x.
Article
CAS
PubMed
Google Scholar
Poulsen K, Ennibi OK, Haubek D: Improved PCR for detection of the highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans in subgingival plaque samples. J Clin Microbiol. 2003, 41: 4829-4932. 10.1128/JCM.41.10.4829-4832.2003.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rudney JD, Chen R, Pan Y: Endpoint quantitative PCR assays for Bacteroides forsythus, Porphyromonas gingivalis, and Actinobacillus actinomycetemcomitans. J Periodontal Res. 2003, 38: 465-470. 10.1034/j.1600-0765.2003.00670.x.
Article
CAS
PubMed
Google Scholar
Saddi-Ortega L, Carvalho MA, Cisalpino PS, Moreira ES: Actinobacillus actinomycetemcomitans genetic heterogeneity: amplification of JP2-like ltx promoter pattern correlated with specific arbitrarily primed polymerase chain reaction (AP-PCR) genotypes from human but not marmoset Brazilian isolates. J Microbiol. 2002, 48: 602-610.
CAS
Google Scholar
Sanz M, Lau L, Herrera D, Morillo JM, Silva A: Methods of detection of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythensis in parodontal microbiology, with special emphasis on advanced molecular techniques: a review. J Clin Periodontol. 2004, 31: 1034-1047. 10.1111/j.1600-051X.2004.00609.x.
Article
CAS
PubMed
Google Scholar
Suzuki N, Nakano Y, Yoshida Y, Ikeda D, Koga T: Identification of Actinobacillus actinomycetemcomitans serotypes by multiplex PCR. J Clin Microbiol. 2001, 39: 2002-2005. 10.1128/JCM.39.5.2002-2005.2001.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yoshida A, Suzuki N, Nakano Y, Oho T, Kawada M, Koga T: Development of a 5' fluorogenic nuclease-based real-time PCR assay for quantitative detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. J Clin Microbiol. 2003, 41: 863-866. 10.1128/JCM.41.2.863-866.2003.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wiebe CB, Putnins EE: The periodontal disease classification system of the American Academy of Periodontology -an update. J Can Dent Assoc. 2000, 66: 594-597.
CAS
PubMed
Google Scholar
Hartroth B, Seyfahrt I, Conrads G: Sampling of periodontal pathogens by paper points: evaluation of basic parameter. Oral Microbiol Immunol. 1999, 14: 326-330. 10.1034/j.1399-302X.1999.140510.x.
Article
CAS
PubMed
Google Scholar
Bommarito S, Peyret N, Santa Lucia J: Thermodynamic parameters for DNA sequences with dangling ends. Nucleic Acids Res. 2000, 28: 1929-1934. 10.1093/nar/28.9.1929.
Article
CAS
PubMed
PubMed Central
Google Scholar
Iannelli F, Giunti L, Pozzi G: Direct sequencing of long polymerase chain reaction fragments. Mol Biotechnol. 1998, 2: 183-5.
Article
Google Scholar
Rasmussen R: Quantification on the LightCycler. Rapid Cycle Real-Time PCR Methods and Applications. Edited by: Meuer S, Wittwer C, Nakagawara K. 1998
Google Scholar
Wittwer C: Rapid Cycle Real Time PCR: Methods and Applications. Rapid Cycle Real-Time PCR Methods and Applications. Edited by: Meuer S, Wittwer C, Nakagawara K. 2001, 1-8.
Chapter
Google Scholar
Cortelli SC, Jorge AO, Cortelli JR, Jordan SF, Haraszthy V: Detection of highly and minimally leukotoxic Actinobacillus actinomycetemcomitans strains in patients with parodontal disease. Pesqui Odontol Bras. 2003, 17: 183-188. 10.1590/S1517-74912003000200016.
Article
PubMed
Google Scholar
Beck JD, Offenbacher S: Systemic effects of periodontitis epidemiology of periodontal disease and cardiovascular disease. J Periodontol. 2005, 76: 2089-100. 10.1902/jop.2005.76.11-S.2089.
Article
PubMed
Google Scholar
Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL: Microbial complexes in subgingival plaque. J Clin Periodontol. 1998, 25: 134-44. 10.1111/j.1600-051X.1998.tb02419.x.
Article
CAS
PubMed
Google Scholar
Tamura K, Nakano K, Hayashibara T, Nomura R, Fujita K, Shintani S, Ooshima T: Distribution of 10 periodontal bacteria in saliva samples from Japanese children and their mothers. Arch Oral Biol. 2005
Google Scholar
Cao SL, Progulske-Fox A, Hillman JD, Handfield M: In vivo induced antigenic determinants of Actinobacillus actinomycetemcomitans. FEMS Microbiol Lett. 2004, 237: 97-103. 10.1111/j.1574-6968.2004.tb09683.x.
Article
CAS
PubMed
Google Scholar
Yang HW, Asikainen S, Dogan B, Suda R, Lai CH: Relationship of Actinobacillus actinomycetemcomitans serotype b to aggressive periodontitis: frequency in pure cultured isolates. J Periodontol. 2004, 75: 592-599. 10.1902/jop.2004.75.4.592.
Article
CAS
PubMed
Google Scholar
Leung WK, Ngai VK, Yau JY, Cheung BP, Tsang PW, Corbet EF: Characterization of Actinobacillus actinomycetemcomitans isolated from young Chinese aggressive periodontitis patients. J Parodontal Res. 2005, 40: 258-268. 10.1111/j.1600-0765.2005.00805.x.
Article
CAS
Google Scholar
Nonnenmacher C, Dalpke A, Mutters R, Heeg K: Quantitative detection of periodontopathogens by real-time PCR. J Microbiol Methods. 2004, 59: 117-125. 10.1016/j.mimet.2004.06.006.
Article
CAS
PubMed
Google Scholar
Cortelli JR, Cortelli SC, Jordan SH, Zambon JJ: Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis. Journal Of Clinical Periodontology. 2005, 32: 860-866. 10.1111/j.1600-051X.2005.00777.x.
Article
PubMed
Google Scholar
Program "HYTHER". [http://ozone.chem.wayne.edu/]
BLAST. [http://www.ncbi.nlm.nih.gov/BLAST/]