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  1. HIV integrase inhibitor use is limited by low genetic barrier to resistance and possible cross-resistance among representatives of this class of antiretrovirals. The aim of this study was to analyse integrase ...

    Authors: Miłosz Parczewski, Dorota Bander, Anna Urbańska and Anna Boroń-Kaczmarska
    Citation: BMC Infectious Diseases 2012 12:368
  2. Wolfsburg HPV Epidemiological Study (WOLVES) is a population-based cohort study on HPV infections and associated diseases in the pre-vaccination era in young women in Wolfsburg, Germany.

    Authors: Karl Ulrich Petry, Alexander Luyten, Annika Justus, Angelika Iftner, Sarah Strehlke, Renate Schulze-Rath and Thomas Iftner
    Citation: BMC Infectious Diseases 2012 12:367
  3. Acute viral respiratory infections are an important cause of morbidity and mortality in humans worldwide. The etiological backgrounds of these infections remain unconfirmed in most clinical cases. The aim of t...

    Authors: Monika Jevšnik, Tina Uršič, Nina Žigon, Lara Lusa, Uroš Krivec and Miroslav Petrovec
    Citation: BMC Infectious Diseases 2012 12:365
  4. Acute kidney injury (AKI) is a complication of severe malaria, and rhabdomyolysis with myoglobinuria is an uncommon cause. We report an unusual case of severe falciparum malaria with dengue coinfection complic...

    Authors: Kok Pin Yong, Ban Hock Tan and Chian Yong Low
    Citation: BMC Infectious Diseases 2012 12:364
  5. In 2009 a new influenza serotype (AH1N1) was identified in Mexico that spread rapidly generating worldwide alarm. San Luis Potosi (SLP) was the third state with more cases reported in that year. The clinical i...

    Authors: Juan Pablo Castillo-Palencia, Lucie Laflamme and Joel Monárrez-Espino
    Citation: BMC Infectious Diseases 2012 12:363
  6. Most cases of hepatitis B virus (HBV) infection and subsequent liver diseases can be prevented with universal newborn HBV vaccination. The attitudes of health care workers about HBV vaccination and their willi...

    Authors: Maia Butsashvili, George Kamkamidze, Marina Topuridze, Dale Morse, Wayne Triner, Jack DeHovitz, Kenrad Nelson and Louise-Anne McNutt
    Citation: BMC Infectious Diseases 2012 12:362
  7. This study aimed to investigate the correlation of minimum inhibiting concentrations (MICs), obtained by broth micro-dilution, and clinical response in patients with cryptococcal meningitis.

    Authors: Chen-Hsiang Lee, Tzu-Yao Chang, Jien-Wei Liu, Fang-Ju Chen, Chun-Chih Chien, Ya-Fen Tang and Cheng-Hsien Lu
    Citation: BMC Infectious Diseases 2012 12:361
  8. The tuberculin skin test (TST) has limitations for latent tuberculosis infection (LTBI) diagnosis in low-prevalence settings. Previously, all TST-positive individuals referred from the community to Baltimore C...

    Authors: Maunank Shah, Kathryn Miele, Howard Choi, Danielle DiPietro, Maria Martins-Evora, Vincent Marsiglia and Susan Dorman
    Citation: BMC Infectious Diseases 2012 12:360
  9. A high complication rate of Q fever in pregnancy is described on the basis of a limited number of cases. All pregnant women with proven Q fever regardless of clinical symptoms should therefore receive long-ter...

    Authors: Katharina Boden, Andreas Brueckmann, Christiane Wagner-Wiening, Beate Hermann, Klaus Henning, Thomas Junghanss, Thomas Seidel, Michael Baier, Eberhard Straube and Dirk Theegarten
    Citation: BMC Infectious Diseases 2012 12:359
  10. Treatment of chronically infected wounds is a challenge, and bacterial environmental contamination is a growing issue in infection control. Ozone may have a role in these situations. The objective of this stud...

    Authors: Belchor Fontes, Ana Maria Cattani Heimbecker, Glacus de Souza Brito, Silvia F Costa, Inneke M van der Heijden, Anna S Levin and Samir Rasslan
    Citation: BMC Infectious Diseases 2012 12:358
  11. Two formulations of Pegylated interferon (Peg-IFN) are on the market for treatment of chronic hepatitis C virus (HCV) infection. The purpose of this meta-analysis was to assess the efficacy of Peg-IFN α-2a ver...

    Authors: Nicola Coppola, Mariantonietta Pisaturo, Gilda Tonziello, Caterina Sagnelli, Evangelista Sagnelli and Italo F Angelillo
    Citation: BMC Infectious Diseases 2012 12:357
  12. Herpes simplex encephalitis (HSE) often leads to severe disability or death. Factors usually associated with outcome include Simplified Acute Physiology Score, age and delay of initiation of acyclovir treatment.

    Authors: Julien Poissy, Karen Champenois, Anny Dewilde, Hugues Melliez, Hugues Georges, Eric Senneville and Yazdan Yazdanpanah
    Citation: BMC Infectious Diseases 2012 12:356
  13. We recently reported the derivation of a diagnostic aid to rule out pneumonia in adults presenting with new onset of cough or worsening of chronic cough and increased body temperature. The aim of the present i...

    Authors: Ulrike Held, Claudia Steurer-Stey, Felix Huber, Sergio Dallafior and Johann Steurer
    Citation: BMC Infectious Diseases 2012 12:355
  14. Beijing genotype strains are the most predominant strains in China. The aim of this study was to explore risk factors and clinical phenotypes associated with infection with Beijing genotype strains among tuber...

    Authors: Yu Pang, Yuanyuan Song, Hui Xia, Yang Zhou, Bing Zhao and Yanlin Zhao
    Citation: BMC Infectious Diseases 2012 12:354
  15. Syphilis is a growing public health problem among men who have sex with men (MSM) globally. Rapid and accurate detection of syphilis is vital to ensure patients and their contacts receive timely treatment and ...

    Authors: Matt Shields, Rebecca J Guy, Neisha J Jeoffreys, Robert J Finlayson and Basil Donovan
    Citation: BMC Infectious Diseases 2012 12:353
  16. People concentrated in congregated systems, such as prisons, are important but often neglected reservoirs for TB transmission, and threaten those in the outside community. Therefore, this study was conducted t...

    Authors: Beyene Moges, Bemnet Amare, Fanaye Asfaw, Wogahta Tesfaye, Moges Tiruneh, Yeshambel Belyhun, Andargachew Mulu and Afework Kassu
    Citation: BMC Infectious Diseases 2012 12:352
  17. Infection with carbapenem-resistant Acinetobacter baumannii has been associated with high morbidity and mortality in solid organ transplant recipients. The main objective of this study was to assess the influence...

    Authors: Erika Ferraz de Gouvêa, Ianick Souto Martins, Marcia Halpern, Adriana Lúcia Pires Ferreira, Samanta Teixeira Basto, Renato Torres Gonçalves, Beatriz Meurer Moreira and Guilherme Santoro-Lopes
    Citation: BMC Infectious Diseases 2012 12:351
  18. Lower respiratory tract infections (LRTI) are responsible for a considerable number of deaths among children, particularly in developing countries. In Egypt and the Middle East region, there is a lack of data ...

    Authors: Caroline F Shafik, Emad W Mohareb, Aymen S Yassin, Madgy A Amin, Amani El Kholy, Hanaa El-Karaksy and Fouad G Youssef
    Citation: BMC Infectious Diseases 2012 12:350
  19. Mycetoma is a chronic, localized, slowly progressing infection of the cutaneous and subcutaneous tissues caused either by fungi (eumycetoma or implantation mycosis) or by aerobic actinomycetes (actinomycetoma)...

    Authors: Sayaphet Rattanavong, Sivay Vongthongchit, Khamhou Bounphamala, Phouvong Vongphakdy, Jacques Gubler, Mayfong Mayxay, Rattanaphone Phetsouvanh, Ivo Elliott, Julie Logan, Robert Hill, Paul N Newton and David Dance
    Citation: BMC Infectious Diseases 2012 12:349
  20. The incidence and mortality from necrotizing fasciitis (NF) are increasing in New Zealand (NZ). Triggered by a media report that traditional Samoan tattooing was causing NF, we conducted a chart review to inve...

    Authors: Dilip Kumar Das, Michael G Baker and Kamalesh Venugopal
    Citation: BMC Infectious Diseases 2012 12:348
  21. Internationally, guidelines to prevent secondary transmission of Shigella infection vary widely. Cases, their contacts with diarrhoea, and those in certain occupational groups are frequently excluded from work, s...

    Authors: Lian Boveé, Jane Whelan, Gerard JB Sonder, Alje P van Dam and Anneke van den Hoek
    Citation: BMC Infectious Diseases 2012 12:347
  22. Genital Human papilloma virus (HPV) is one of the most commonly diagnosed Sexually Transmitted Infection (STIs) in men and women. Knowledge about HPV infection among men is limited. This study aims to determin...

    Authors: Vivian Colón-López, Ana P Ortiz, Lizbeth M Del Toro-Mejías, Hermes García, Michael C Clatts and Joel Palefsky
    Citation: BMC Infectious Diseases 2012 12:346
  23. Household transmission of influenza-like illness (ILI) may vary with viral and demographic characteristics. We examined the effect of these factors in a population-based sample of adults with ILI.

    Authors: James M McCaw, Peter F Howard, Peter C Richmond, Michael Nissen, Theo Sloots, Stephen B Lambert, Michael Lai, Michael Greenberg, Terry Nolan and Jodie McVernon
    Citation: BMC Infectious Diseases 2012 12:345
  24. Current guidelines regarding Lyme neuroborreliosis [LNB] require the presence of intrathecal Borrelia burgdorferi-specific antibody production for the definite diagnosis of LNB. However, about 20% of early stage ...

    Authors: Johannes P Borde, Simone Meier, Volker Fingerle, Christiane Klier, Johannes Hübner and Winfried V Kern
    Citation: BMC Infectious Diseases 2012 12:344
  25. Compared to methicillin-resistant Staphylococcus aureus (MRSA), characteristics of nasal carriage and community-onset infection methicillin-susceptible S. aureus (MSSA) are less well known. No characteristics of ...

    Authors: Feng-Jui Chen, Leung-Kei Kristopher Siu, Jung-Chung Lin, Chen-Her Wang and Po-Liang Lu
    Citation: BMC Infectious Diseases 2012 12:343
  26. Activation of the A2A adenosine receptor (A2AAR) decreases production of inflammatory cytokines, prevents C. difficile toxin A-induced enteritis and, in combination with antibiotics, increases survival from sepsi...

    Authors: Yuesheng Li, Robert A Figler, Glynis Kolling, Tara C Bracken, Jayson Rieger, Ralph W Stevenson, Joel Linden, Richard L Guerrant and Cirle Alcantara Warren
    Citation: BMC Infectious Diseases 2012 12:342
  27. Men who have sex with men (MSM) especially those who are HIV positive are at risk for HPV-associated anal cancer. We systematically reviewed studies with data on the prevalence of vaccine preventable anal HPV ...

    Authors: Huachun Zou, Christopher K Fairley, Jane S Hocking, Suzanne M Garland, Andrew E Grulich and Marcus Y Chen
    Citation: BMC Infectious Diseases 2012 12:341
  28. Appropriate induction of the early Th1 cytokine IL-12 is a critical defense directed against viral infection. We have previously shown that different viruses elicited either IL-12 or IFNα dependent Th1 reactio...

    Authors: Rong-Fu Chen, Lin Wang, Jiin-Tsuey Cheng and Kuender D Yang
    Citation: BMC Infectious Diseases 2012 12:340
  29. Background rates of latent tuberculosis infection in low prevalence regions of Britain are unknown. These would be valuable data for interpreting positive IGRA results, and guiding cost-benefit analyses. The m...

    Authors: Timothy SC Hinks, Nimu Varsani, David T Godsiff, Thomas C Bull, Katherine L Nash, Lisa McLuckie, Catherine Maule, Tessa Flower and Anthony Warley
    Citation: BMC Infectious Diseases 2012 12:339
  30. The incidence of syphilis is increasing in many parts of the world. Clinicians may have limited experience in the diagnosis when the clinical appearance is unusual. If early diagnosis is not made and prompt tr...

    Authors: Kejian Zhu, Qiang Zhou, Rui Han and Hao Cheng
    Citation: BMC Infectious Diseases 2012 12:338
  31. Toxoplasmosis is a common parasitic infection caused by an obligate intracellular protozoan, Toxoplasma gondii. If primary toxoplasmosis occurs during pregnancy about one third of the cases could lead to congenit...

    Authors: Endalew Zemene, Delenasaw Yewhalaw, Solomon Abera, Tariku Belay, Abdi Samuel and Ahmed Zeynudin
    Citation: BMC Infectious Diseases 2012 12:337
  32. Schools are important foci of influenza transmission and potential targets for surveillance and interventions. We compared several school-based influenza monitoring systems with clinic-based influenza-like ill...

    Authors: Shu E Soh, Alex R Cook, Mark IC Chen, Vernon J Lee, Jeffery L Cutter, Vincent TK Chow, Nancy WS Tee, Raymond TP Lin, Wei-Yen Lim, Ian G Barr, Cui Lin, Meng Chee Phoon, Li Wei Ang, Sunil K Sethi, Chia Yin Chong, Lee Gan Goh…
    Citation: BMC Infectious Diseases 2012 12:336
  33. Bronchofiberscopy, a widely used procedure for the diagnosis of various pulmonary diseases within intensive care units, has a history of association with nosocomial infections. Between September and November 2...

    Authors: Yukun Xia, CuiLing Lu, Jingya Zhao, Gaige Han, Yong Chen, Fang Wang, Bin Yi, Guoqin Jiang, Xiaohua Hu, Xianfeng Du, Zheng Wang, Hong Lei, Xuelin Han and Li Han
    Citation: BMC Infectious Diseases 2012 12:335
  34. Routine cytomegalovirus (CMV) screening during pregnancy is not recommended in the United States and the extent to which it is performed is unknown. Using a medical claims database, we computed rates of CMV-sp...

    Authors: Jessica Leung, Michael J Cannon, Scott D Grosse and Stephanie R Bialek
    Citation: BMC Infectious Diseases 2012 12:334
  35. This epidemiological study was carried out in Sfax (south of Tunisia) and focused on genital Chlamydia trachomatis (C. trachomatis) genovar distribution.

    Authors: Houda Gharsallah, Olfa Frikha-Gargouri, Hanen Sellami, Fatma Besbes, Abir Znazen and Adnene Hammami
    Citation: BMC Infectious Diseases 2012 12:333
  36. Brain abscess is a potentially fatal disease. This study assesses clinical aspects of brain abscess in a large hospital cohort.

    Authors: Jannik Helweg-Larsen, Arnar Astradsson, Humeira Richhall, Jesper Erdal, Alex Laursen and Jannick Brennum
    Citation: BMC Infectious Diseases 2012 12:332
  37. Critically ill patients including trauma patients are at high risk of urinary tract infection (UTI). The composition of urine in trauma patients may be modified due to inflammation, systemic stress, rhabdomyol...

    Authors: Cecile Aubron, Olivier Huet, Sylvie Ricome, Didier Borderie, Eric Pussard, Pierre-Etienne Leblanc, Odile Bouvet, Eric Vicaut, Erick Denamur and Jacques Duranteau
    Citation: BMC Infectious Diseases 2012 12:330
  38. Pre-existing cellular immunity has been recognized as one of the key factors in determining the outcome of influenza infection by reducing the likelihood of clinical disease and mitigates illness. Whether, and...

    Authors: Venkata R Duvvuri, Jane M Heffernan, Seyed M Moghadas, Bhargavi Duvvuri, Hongbin Guo, David N Fisman, Jianhong Wu and Gillian E Wu
    Citation: BMC Infectious Diseases 2012 12:329
  39. Tumor necrosis factor alpha (TNF-α) plays a key role in the containment of tuberculosis. The relationship between the TNF -238G/A polymorphism and tuberculosis susceptibility remains inconclusive. A comprehens...

    Authors: Zhijiao Zhang, Hang Zhu, Xudi Pu, Siying Meng, Fan Zhang, Lei Xun, Qin Liu and Yang Wang
    Citation: BMC Infectious Diseases 2012 12:328
  40. Enterovirus 71 (EV71) infection can induce the apoptosis of infected cells. The aim of this study is to explore the effect of EV71 infection on apoptosis mechanisms in virus-infected human rhabdomyosarcoma (RD...

    Authors: Weifeng Shi, Xiang Li, Xueling Hou, Hongjun Peng, Qingbo Jiang, Mei Shi, Yun Ji, Xiping Liu and Jinbo Liu
    Citation: BMC Infectious Diseases 2012 12:327
  41. Tuberculosis (TB) is a disease of poverty that contributes significantly to ill-health in developing countries. Drug resistant TB is a major challenge to disease control. Early diagnosis and rapid determinatio...

    Authors: Chamila P Adikaram, Jennifer Perera and Sandya S Wijesundera
    Citation: BMC Infectious Diseases 2012 12:326
  42. The Human Immunodeficiency Virus type 1 (HIV-1) envelope glycoprotein gp160, useful in detecting anti-HIV-1 antibodies, is difficult to express in heterologous hosts. The major hurdles are its signal sequence,...

    Authors: Sheikh M Talha, Satish Kumar Nemani, Teppo Salminen, Sushil Kumar, Sathyamangalam Swaminathan, Tero Soukka, Kim Pettersson and Navin Khanna
    Citation: BMC Infectious Diseases 2012 12:325
  43. The importance of the reduction in hepatitis C virus (HCV) RNA levels 4 and 12 weeks after starting peginterferon (PEG-IFN) and ribavirin combination therapy has been reported to predict a sustained virologic ...

    Authors: Hidenori Toyoda, Takashi Kumada, Noritomo Shimada, Koichi Takaguchi, Tatsuya Ide, Michio Sata, Hiroyuki Ginba, Kazuhiro Matsuyama and Namiki Izumi
    Citation: BMC Infectious Diseases 2012 12:324
  44. Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reco...

    Authors: Mónica Fernández-Sánchez, Marcela Saeb-Lima, Claudia Alvarado-de la Barrera and Gustavo Reyes-Terán
    Citation: BMC Infectious Diseases 2012 12:323
  45. Emphysematous cystitis (EC) is a comparatively rare urinary tract infection characterized by air within the bladder wall and lumen and is usually associated with immunosuppression or poorly controlled diabetes...

    Authors: Takeshi Hashimoto, Kazunori Namiki, Ayako Tanaka, Kenji Shimodaira, Tatsuo Gondo and Masaaki Tachibana
    Citation: BMC Infectious Diseases 2012 12:322
  46. Chronic wounds affect millions of people and cost billions of dollars in the United States each year. These wounds harbor polymicrobial biofilm communities, which can be difficult to elucidate using culturing ...

    Authors: Daniel D Rhoads, Stephen B Cox, Eric J Rees, Yan Sun and Randall D Wolcott
    Citation: BMC Infectious Diseases 2012 12:321
  47. Urinary tract infections (UTI) are one of the most common infections among women worldwide. E. coli often causes more than 75% of acute uncomplicated UTI, however, little is known about how recurrent UTIs and ind...

    Authors: Louise Ladefoged Poulsen, Magne Bisgaard, Nguyen Thai Son, Nguyen Vu Trung, Hoang Manh An and Anders Dalsgaard
    Citation: BMC Infectious Diseases 2012 12:320
  48. Campylobacter is a common cause of bacterial gastro-enteritis characterized by multiple environmental sources and transmission pathways. Ecological studies can be used to reveal important regional characterist...

    Authors: Julie Arsenault, Olaf Berke, Pascal Michel, André Ravel and Pierre Gosselin
    Citation: BMC Infectious Diseases 2012 12:318
  49. High plasma viremia in HIV-1 infection is associated with rapid CD4 cell decline and faster disease progression. Children with HIV infection have high viral loads, particularly in early childhood. In this stud...

    Authors: Ujjwal Neogi, Pravat Nalini Sahoo, Ayesha De Costa and Anita Shet
    Citation: BMC Infectious Diseases 2012 12:317

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