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  1. Content type: Research article

    Streptococcus pneumoniae is a major human pathogen, and nasopharyngeal colonization is the first step for transmission and pathogenesis of pneumococcal diseases. Ethiopia introduced the 10-valent pneumococcal con...

    Authors: Wondewosen Tsegaye Sime, Abraham Aseffa, Yimtubezenash Woldeamanuel, Sarah Brovall, Eva Morfeldt and Birgitta Henriques-Normark

    Citation: BMC Infectious Diseases 2019 19:409

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  2. Content type: Research article

    In co-endemic areas, rate of intestinal parasites and tuberculosis (TB) co-infection thought to be high. However, there are limited studies on the epidemiology of this co-infection in Ethiopia. Therefore, the ...

    Authors: Ayinalem Alemu, Abebaw Kebede, Biniyam Dagne, Misikir Amare, Getu Diriba, Bazezew Yenew, Ephrem Tesfaye, Mengistu Tadesse, Waganeh Sinshaw, Dawit Challa and Kassu Desta

    Citation: BMC Infectious Diseases 2019 19:407

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  3. Content type: Research article

    In Ethiopia, like other developing countries, intestinal parasitic infections are the major public health problems affecting millions annually. Overcrowding and poor living conditions are the major risk factor...

    Authors: Fitsum Mardu, Mekonnen Yohannes and Desalegn Tadesse

    Citation: BMC Infectious Diseases 2019 19:406

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  4. Content type: Research article

    Tuberculosis (TB) and HIV makeup a deadly synergy of infectious disease, and the combined effect is apparent in resource limited countries like Ethiopia. Previous studies have demonstrated inconsistent results...

    Authors: Demeke Geremew, Aklilu Endalamaw, Markos Negash, Setegn Eshetie and Belay Tessema

    Citation: BMC Infectious Diseases 2019 19:405

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  5. Content type: Research article

    Implementation of sputum Gram stain in the initial assessment of community-acquired pneumonia (CAP) patients is still controversial. We performed a systematic review and meta-analysis to investigate the useful...

    Authors: Gaspar Del Rio-Pertuz, Juan F. Gutiérrez, Abel J. Triana, Jorge L. Molinares, Andrea B. Robledo-Solano, José L. Meza, Orlando M. Ariza-Bolívar, Jorge Acosta-Reyes, Argenis Garavito, Diego Viasus and Jordi Carratalà

    Citation: BMC Infectious Diseases 2019 19:403

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  6. Content type: Research article

    France is the European country with the lowest level of confidence in vaccines. Measurement of patients’ acceptability towards a future therapeutic HIV vaccine is critically important. Thus, the aim of this st...

    Authors: Svetlane Dimi, David Zucman, Olivier Chassany, Christophe Lalanne, Thierry Prazuck, Emmanuel Mortier, Catherine Majerholc, Isabelle Aubin-Auger, Pierre Verger and Martin Duracinsky

    Citation: BMC Infectious Diseases 2019 19:401

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  7. Content type: Research article

    Older adults are vulnerable to hospitalization or death from norovirus infection, but the actual disease burden remains unknown. Therefore, we conducted a nationwide survey to estimate the number of inpatients...

    Authors: Satoko Ohfuji, Kyoko Kondo, Kazuya Ito, Tetsuo Kase, Akiko Maeda, Wakaba Fukushima, Taisei Masuda and Munehide Kano

    Citation: BMC Infectious Diseases 2019 19:400

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  8. Content type: Research article

    Uptake of Human Immunodeficiency Virus (HIV) re-testing among postnatal mothers who had previously tested HIV-negative is crucial for the detection of recent seroconverters who are likely to have high plasma v...

    Authors: Saumu Iddy Nungu, Janneth Maridadi Mghamba, Susan Fred Rumisha and Innocent Antony Semali

    Citation: BMC Infectious Diseases 2019 19:398

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  9. Content type: Research article

    Tuberculosis (TB) is the ninth leading cause of death worldwide and the leading cause from a single infectious agent. Bacillus Calmette-Guerin (BCG) is the only licensed vaccine for TB, yet its efficacy remain...

    Authors: Eileen Sweeney, Darren Dahly, Nahed Seddiq, Gerard Corcoran, Mary Horgan and Corinna Sadlier

    Citation: BMC Infectious Diseases 2019 19:397

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  10. Content type: Case report

    Leptospirosis or Weil’s disease is caused by pathogenic spirochete bacteria called Leptospira. It is considered the most common zoonosis in the world and is usually transmitted by urine of rodents and dogs with a...

    Authors: Alexander Maier, Rafael Kaeser, Robert Thimme and Tobias Boettler

    Citation: BMC Infectious Diseases 2019 19:395

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  11. Content type: Case report

    Thrombotic thrombocytopenic purpura (TTP) is a rare, potentially fatal disease with multisystem involvement. Cytomegalovirus (CMV) infection as a cause of refractory TTP, has been reported only in immunocompro...

    Authors: Medhini Boteju, Praveen Weeratunga, Ahalyaa Sivashangar and Thashi Chang

    Citation: BMC Infectious Diseases 2019 19:394

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  12. Content type: Research article

    Human immunodeficiency virus, hepatitis B virus and hepatitis C virus are among the greatest threats to blood safety for the recipient. They are also the leading cause of death, chronic and life-threatening ab...

    Authors: Abiye Tigabu, Tigist Engda and Feleke Mekonnen

    Citation: BMC Infectious Diseases 2019 19:393

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  13. Content type: Research article

    In Lao PDR, the epidemiology of varicella infection is uncertain, since it is not a notifiable disease and VZV outbreaks are rarely reported as fever/rash (F/R) diseases.

    Authors: Phonethipsavanh Nouanthong, Judith M. Hübschen, Somxay Billamay, Sodaly Mongkhoune, Keooudomphone Vilivong, Vilaysone Khounvisith, Regina Sinner, Marc Grandadam, Darouny Phonekeo, Antony P. Black and Claude P. Muller

    Citation: BMC Infectious Diseases 2019 19:392

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  14. Content type: Research article

    Most studies assessing drug resistant tuberculosis (DRTB) in human immunodeficiency virus (HIV) co-infected patients in India have used conventional culture- based systems to diagnose DRTB that have a longer t...

    Authors: Neil Saldanha, Kiran Runwal, Charulata Ghanekar, Sunil Gaikwad, Shrivallabh Sane and Sanjay Pujari

    Citation: BMC Infectious Diseases 2019 19:391

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  15. Content type: Case report

    The compound letermovir (LMV) has recently been approved for the prophylaxis of cytomegalovirus (CMV) infection and disease in adult CMV seropositive recipients of an allogeneic hematopoietic stem cell transpl...

    Authors: Susanne Jung, Manuela Michel, Thomas Stamminger and Detlef Michel

    Citation: BMC Infectious Diseases 2019 19:388

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  16. Content type: Research article

    In August 2017, the Uganda Ministry of Health was notified of increased cases of multidrug-resistant tuberculosis (MDR-TB) in Arua District, Uganda during 2017. We investigated to identify the scope of the inc...

    Authors: Denis Okethwangu, Doreen Birungi, Claire Biribawa, Benon Kwesiga, Stavia Turyahabwe, Alex R. Ario and Bao-Ping Zhu

    Citation: BMC Infectious Diseases 2019 19:387

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  17. Content type: Case report

    Ewingella americana (Ea) is a Gram-negative, lactose-fermenting, oxidase-negative and catalase-positive bacterium that was first described in 1983 as a new genus and species in the family Enterobacteriaceae. It i...

    Authors: Susanna Esposito, Francesco Miconi, Daniela Molinari, Emanuela Savarese, Federica Celi, Livio Marchese, Sara Valloscuro, Giovanni Miconi and Nicola Principi

    Citation: BMC Infectious Diseases 2019 19:386

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  18. Content type: Research article

    An outbreak of Candida auris began globally in 2014 including Pakistan and since then it has emerged as a nosocomial multi-drug resistant pathogen. The aim of this study was to assess the clinical spectrum and ou...

    Authors: Muneeba Ahsan Sayeed, Joveria Farooqi, Kausar Jabeen, Safia Awan and Syed Faisal Mahmood

    Citation: BMC Infectious Diseases 2019 19:384

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  19. Content type: Research article

    Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections. The human immunodeficienc...

    Authors: Henok Mulugeta, Getenet Dessie, Fasil Wagnew, Dube Jara, Cheru Tesema Leshargie and Ayenew Negesse

    Citation: BMC Infectious Diseases 2019 19:383

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  20. Content type: Research article

    Herpes simplex virus type-2 (HSV-2) infection is the main cause of genital ulcer disease and increases the risk of HIV acquisition. Little information is available regards the epidemiological characteristics o...

    Authors: Pengcheng Huai, Furong Li, Zhen Li, Lele Sun, Xi’an Fu, Qing Pan, Gongqi Yu, Zemin Chai, Tongsheng Chu, Zihao Mi, Fangfang Bao, Honglei Wang, Bingni Zhou, Chuan Wang, Yonghu Sun, Guiye Niu…

    Citation: BMC Infectious Diseases 2019 19:382

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  21. Content type: Research article

    The epidemiology of hepatitis B virus (HBV) infection in the general population in Rwanda is not well known. This study examined the prevalence of HBV surface antigen (HBsAg) positivity and associated risk fac...

    Authors: Jean Damascene Makuza, Jean Olivier Twahirwa Rwema, Corneille Killy Ntihabose, Donatha Dushimiyimana, Justine Umutesi, Marie Paul Nisingizwe, Janvier Serumondo, Muhamed Semakula, David J. Riedel and Sabin Nsanzimana

    Citation: BMC Infectious Diseases 2019 19:381

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  22. Content type: Research article

    Antiretroviral therapy (ART) has significantly decreased HIV/AIDS-related morbidity and mortality. However, globally, many people living with HIV die from non-AIDS related illnesses including liver diseases wh...

    Authors: Faustina Pappoe, Charles Kofi Oheneba Hagan, Dorcas Obiri-Yeboah and Paul Nsiah

    Citation: BMC Infectious Diseases 2019 19:380

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  23. Content type: Research article

    The incidence of tuberculosis (TB) remains high worldwide. Current strategies will not eradicate TB by 2035; instead, by 2182 is more likely. Therefore, it is urgent that new risk factors be identified.

    Authors: Yingjie Zhang, Mengyang Liu, Samuel S. Wu, Hui Jiang, Junjie Zhang, Songwang Wang, Wei Ma, Qihuan Li, Yuan Ma, Yue Liu, Wei Feng, Endawoke Amsalu, Xia Li, Wei Wang, Weimin Li and Xiuhua Guo

    Citation: BMC Infectious Diseases 2019 19:379

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  24. Content type: Research article

    Treatments for Hepatitis C virus (HCV) infection have vastly improved over the past few decades with current regimens now offering pangenotypic activity with excellent cure rates reported in clinical trials, i...

    Authors: A. Maughan, K. Sadigh, V. Angulo-Diaz, C. Mandimika, M. Villanueva, J. K. Lim and O. Ogbuagu

    Citation: BMC Infectious Diseases 2019 19:378

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  25. Content type: Research article

    Climate change is expected to increase the chance of extreme rainfall events in the Northern Hemisphere and herewith, there is an increased chance of urban pluvial flooding. Urban pluvial flooding often consis...

    Authors: Annemieke Christine Mulder, Roan Pijnacker, Heleen de Man, Jan van de Kassteele, Wilfrid van Pelt, Lapo Mughini-Gras and Eelco Franz

    Citation: BMC Infectious Diseases 2019 19:377

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  26. Content type: Research article

    Management of Ebola virus disease (EVD) has historically focused on infection prevention, case detection and supportive care. Several specific anti-Ebola therapies have been investigated, including during the ...

    Authors: James S. Lee, Neill K. J. Adhikari, Henry Y. Kwon, Koren Teo, Reed Siemieniuk, François Lamontagne, Adrienne Chan, Sharmistha Mishra, Srinivas Murthy, Peter Kiiza, Jan Hajek, Elhadj I. Bah, Marie-Claire Lamah, Raymond Kao and Robert A. Fowler

    Citation: BMC Infectious Diseases 2019 19:376

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  27. Content type: Research article

    This study was undertaken to determine the distribution of type-specific human papillomavirus (HPV) in external anogenital warts, and the correlation with clinical presentation of warts and demographic data of...

    Authors: Rana Al-Awadhi, Nawaf Al-Mutairi, Ahmed N. Albatineh and Wassim Chehadeh

    Citation: BMC Infectious Diseases 2019 19:375

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  28. Content type: Research article

    Dosages of anti-tuberculosis (TB) drugs are recommended to be adjusted according to renal function for patients complicated with chronic kidney disease (CKD). However, the efficacy and safety outcomes of such ...

    Authors: Nayuta Saito, Yutaka Yoshii, Yugo Kaneko, Akio Nakashima, Tsugumi Horikiri, Zenya Saito, Sho Watanabe, Akira Kinoshita, Keisuke Saito and Kazuyoshi Kuwano

    Citation: BMC Infectious Diseases 2019 19:374

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  29. Content type: Research article

    Body mass index (BMI) may contribute somewhat to drug metabolism, and thus affecting the efficacy of highly active antiretroviral therapy (HAART). This study aimed to determine the frequencies of underweight, ...

    Authors: Xiaolin Li, Haibo Ding, Wenqing Geng, Jing Liu, Yongjun Jiang, Junjie Xu, Zining Zhang and Hong Shang

    Citation: BMC Infectious Diseases 2019 19:373

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  30. Content type: Research article

    In the UK, hepatitis B virus (HBV) incidence is associated with migrants from particular high-burden countries and population groups deemed ‘hard-to-reach’ by standard healthcare services: the homeless, people...

    Authors: Josephine E. B. Taylor, Julian Surey, Jennifer MacLellan, Marie Francis, Ibrahim Abubakar and Helen R. Stagg

    Citation: BMC Infectious Diseases 2019 19:372

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  31. Content type: Research article

    There is an ongoing outbreak of Mycobacterium chimaera infections among patients exposed to contaminated heater-cooler devices used during cardiac surgery. Recognition of M. chimaera infection is hampered by its ...

    Authors: Jim Nomura, Gunter Rieg, Gary Bluestone, Townson Tsai, Andrew Lai, Dawn Terashita, Sivan Bercovici, David K. Hong and Brian P. Lee

    Citation: BMC Infectious Diseases 2019 19:371

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  32. Content type: Research article

    Several inactivated enterovirus-A71 (EV-A71) vaccines are currently licensed in China; however, the development of additional EV-A71 vaccines is ongoing, necessitating extensive analysis of the molecular epide...

    Authors: Lea Necitas Apostol, Hiroyuki Shimizu, Akira Suzuki, Rifqiyah Nur Umami, Maria Melissa Ann Jiao, Amado Tandoc III, Mariko Saito, Socorro Lupisan and Hitoshi Oshitani

    Citation: BMC Infectious Diseases 2019 19:370

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  33. Content type: Research article

    Urinary tract infections (UTIs) are one of the most common bacterial infections. High recurrence rates and the increasing antibiotic resistance among uropathogens constitute a large social and economic problem...

    Authors: Urszula Wnorowska, Ewelina Piktel, Bonita Durnaś, Krzysztof Fiedoruk, Paul B. Savage and Robert Bucki

    Citation: BMC Infectious Diseases 2019 19:369

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  34. Content type: Study protocol

    The Joint United Nations Programme on HIV/AIDS 90–90-90 goal envisions 90% of all people receiving antiretroviral therapy to be virally suppressed by 2020. Implied in that goal is that viral load be quantified...

    Authors: Seema T. Meloni, Oche Agbaji, Charlotte A. Chang, Patricia Agaba, Godwin Imade, Stephen Oguche, Ahmed Mukhtar, Kiren Mitruka, Mackenzie Hurlston Cox, Aaron Zee and Phyllis Kanki

    Citation: BMC Infectious Diseases 2019 19:368

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  35. Content type: Research article

    Independent of HIV infection, extrapulmonary TB (EPTB) risk is increased in women, persons of black race or foreign birth, and by genetic variants in vitamin D receptor (VDR), interleukin-1 beta (IL-1β), and t...

    Authors: Christina T. Fiske, Amondrea Blackman, Fernanda Maruri, Peter F. Rebeiro, Moises Huaman, Jamie Kator, Holly M. Scott Algood and Timothy R. Sterling

    Citation: BMC Infectious Diseases 2019 19:366

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  36. Content type: Research article

    Tuberculosis (TB) is an important public health issue worldwide. However, evidence concerning the impact of environmental factors on TB is sparse. We performed a retrospective analysis to determine the spatiot...

    Authors: Xuemei Wang, Shaohua Yin, Yunpeng Li, Wenrui Wang, Maolin Du, Weidong Guo, Mingming Xue, Jing Wu, Danyan Liang, Ruiqi Wang, Dan Liu and Di Chu

    Citation: BMC Infectious Diseases 2019 19:365

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  37. Content type: Research article

    Whilst previous work has identified clustering of the active trachoma sign “trachomatous inflammation—follicular” (TF), there is limited understanding of the spatial structure of trachomatous trichiasis (TT), ...

    Authors: Rebecca Mann Flueckiger, Emanuele Giorgi, Jorge Cano, Mariamo Abdala, Olga Nelson Amiel, Gilbert Baayenda, Ana Bakhtiari, Wilfrid Batcho, Kamal Hashim Bennawi, Michael Dejene, Balgesa Elkheir Elshafie, Aba Ange Elvis, Missamou François, André Goepogui, Khumbo Kalua, Biruck Kebede…

    Citation: BMC Infectious Diseases 2019 19:364

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  38. Content type: Research article

    Hepatitis B virus (HBV) reactivation is one of the most common precipitating events associated with acute decompensation (AD) or acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB)-related cirrh...

    Authors: Jian-Hua Lei, Feng Peng, Zi Chen and Xin-Qiang Xiao

    Citation: BMC Infectious Diseases 2019 19:363

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  39. Content type: Research article

    Ischemic stroke is a common complication in patients with tuberculous meningitis (TBM), which is associated with poor clinical outcome. However, risk factors of stroke in TBM patients were not fully understood...

    Authors: Liming Zhang, Xiaoyu Zhang, Huaqiang Li, Gang Chen and Meijia Zhu

    Citation: BMC Infectious Diseases 2019 19:362

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  40. Content type: Research article

    Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that is widely identified worldwide. This study aimed to investigate the phenotypic characterization and molecular typing of Clostridium difficile is...

    Authors: Parisa Shoaei, Hasan Shojaei, Mohammad Jalali, Farzin Khorvash, Sayed Mohsen Hosseini, Behrooz Ataei, Bahareh Vakili, Fatemeh Ebrahimi, Hossein Tavakoli, Zahra Esfandiari and J. Scott Weese

    Citation: BMC Infectious Diseases 2019 19:361

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  41. Content type: Research article

    Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. The disease affects all ages and both sexes but more prevalent among the sexually active age group of 15–49 years. The purp...

    Authors: Martin Banong-le, Samuel Kwabena Ofosu and Francis Anto

    Citation: BMC Infectious Diseases 2019 19:360

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  42. Content type: Case report

    Necrotizing fasciitis is a deep infection of the fascia and subcutaneous tissue with a high mortality rate. Meningitis is an infection of the membranes surrounding the brain with a likewise high mortality rate. S...

    Authors: Nichlas Hovmand, Sarah Byberg, Morten Bo Larsen, Daria Podlekareva, David Levarett Buck and Birgitte Rønde Hansen

    Citation: BMC Infectious Diseases 2019 19:358

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  43. Content type: Research article

    Varicella during pregnancy can lead to serious maternal and fetal consequences. Although an effective vaccine is available it is not incorporated in to the routine vaccination programs in most of the Asian cou...

    Authors: Ishara P. Premathilake, Praveena Aluthbaduge, Channa P. Senanayake, Renuka Jayalatharachchi, Sirithilak Gamage and Jude Jayamaha

    Citation: BMC Infectious Diseases 2019 19:356

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  44. Content type: Research article

    In developing countries particularly in sub-Saharan Africa trachoma is still a public health concern. Ethiopia is the most affected of all and bears the highest burden of active trachoma. In spite of this, the...

    Authors: Kemal Kassim, Jeylan Kassim, Rameto Aman, Mohammedawel Abduku, Mekonnen Tegegne and Biniyam Sahiledengle

    Citation: BMC Infectious Diseases 2019 19:353

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