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  1. Content type: Research article

    Acute undifferentiated febrile illness (AUFI) is caused by a multitude of diverse pathogens, with significant morbidity and mortality in the developing world. The objective of this review was to characterise t...

    Authors: Kinley Wangdi, Kaushalya Kasturiaratchi, Susana Vaz Nery, Colleen L. Lau, Darren J. Gray and Archie C. A. Clements

    Citation: BMC Infectious Diseases 2019 19:577

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  2. Content type: Research article

    Hospital environment in patient care has been linked on healthcare-associated infections (HAI). No touch disinfection technologies that utilize pulsed xenon ultraviolet light has been recognized to prevent inf...

    Authors: José E. Villacís, Mario Lopez, Deborah Passey, Manuel Hernando Santillán, Germán Verdezoto, Freddy Trujillo, Gustavo Paredes, Carmen Alarcón, Ronny Horvath and Mark Stibich

    Citation: BMC Infectious Diseases 2019 19:575

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  3. Content type: Research article

    Blood donor plasma samples were detected by the Ultrio Plus NAT system for HBV, HCV and HIV-1 in Shenzhen blood center, China. Reactive samples underwent further discriminatory testing of a single virus by the...

    Authors: Xianlin Ye, Tong Li, Wen Shao, Jinfeng Zeng, Wenxu Hong, Liang Lu, Weigang Zhu, Chengyao Li and Tingting Li

    Citation: BMC Infectious Diseases 2019 19:574

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  4. Content type: Study protocol

    Solid organ transplantation (SOT) is a well-established and life-saving treatment for patients with end-stage organ failure. Organ rejection and infections are among the main complications to SOT and largely d...

    Authors: Camilla Heldbjerg Drabe, Søren Schwartz Sørensen, Allan Rasmussen, Michael Perch, Finn Gustafsson, Omid Rezahosseini, Jens D. Lundgren, Sisse Rye Ostrowski and Susanne Dam Nielsen

    Citation: BMC Infectious Diseases 2019 19:573

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  5. Content type: Research article

    We conducted a diagnostic surveillance study to identify Plasmodium, dengue virus, chikungunya virus, and Orientia tsutsugamushi infections among febrile patients who underwent triage for malaria in the outpatien...

    Authors: Pavitra N. Rao, Anna Maria van Eijk, Sandhya Choubey, Syed Zeeshan Ali, Aditee Dash, Punam Barla, Rajshri Rani Oraon, Gautam Patel, P. Nandini, Subrata Acharya, Sanjib Mohanty, Jane M. Carlton and Sanghamitra Satpathi

    Citation: BMC Infectious Diseases 2019 19:572

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  6. Content type: Research article

    Carbapenemase-producing organisms (CPOs) have emerged as antibiotic-resistant bacteria of global concern. Here we assessed the performance of the Carba (beta) assay, a multiplex real-time PCR assay developed b...

    Authors: Amanda Bordin, Ella Trembizki, Madeline Windsor, Rachel Wee, Lit Yeen Tan, Cameron Buckley, Melanie Syrmis, Haakon Bergh, Kyra Cottrell, Hosam M. Zowawi, Hanna E. Sidjabat, Patrick N. A. Harris, Graeme R. Nimmo, David L. Paterson and David M. Whiley

    Citation: BMC Infectious Diseases 2019 19:571

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  7. Content type: Case report

    Kodamaea ohmeri is a yeast is frequently mistaken for Candida, which belongs to the same family. This micro-organism has been reported to cause life-threatening infections in humans.

    Authors: K. Diallo, B. Lefevre, G. Cadelis, J. C. Gallois, F. Gandon, M. Nicolas and B. Hoen

    Citation: BMC Infectious Diseases 2019 19:570

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  8. Content type: Research article

    Antiretroviral therapy (ART) was rolled-out in Ethiopia in 2005, but there are no reports on outcome of ART and human immunodeficiency virus drug resistance (HIVDR) at national level. We described acquired dru...

    Authors: Nigus Fikrie Telele, Amare Worku Kalu, Solomon Gebre-Selassie, Daniel Fekade, Gaetano Marrone, Sebastian Grossmann, Ujjwal Neogi, Belete Tegbaru and Anders Sönnerborg

    Citation: BMC Infectious Diseases 2019 19:569

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  9. Content type: Research article

    With the aim of preparing a more effective, safe and economical vaccine for tuberculosis, inhalable live mycobacterium formulations were evaluated.

    Authors: Puja S. Nagpal, Ashwani Kesarwani, Parul Sahu and Pramod Upadhyay

    Citation: BMC Infectious Diseases 2019 19:568

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  10. Content type: Research article

    Increasing multidrug-resistant tuberculosis (MDR-TB) incidence is a major threat against TB eradication worldwide. We aim to conduct a detailed MDR-TB study in Portugal, an European country with endemic TB, co...

    Authors: Olena Oliveira, Rita Gaio, Carlos Carvalho, Margarida Correia-Neves, Raquel Duarte and Teresa Rito

    Citation: BMC Infectious Diseases 2019 19:567

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  11. Content type: Research article

    To infer transmission direction of a HIV transmission chain is helpful not only in legal jurisdiction but also in precise intervention to prevent HIV spread. Recently, the direction of transmission is inferred...

    Authors: Jianjun Wu, Zhongwang Hu, Hui Yao, Hai Wang, Yanhua Lei, Ping Zhong, Yi Feng, Hui Xing, Yuelan Shen, Lin Jin, Aiwen Liu, Yizu Qin, Lifeng Miao, Bin Su, Yibo Zhang and Hongxiong Guo

    Citation: BMC Infectious Diseases 2019 19:566

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  12. Content type: Research article

    To detect carbapenemase-producing Gram-negative bacteria in bacterial laboratories at medical settings, a new immunochromatographic assay for New Delhi metallo-β-lactamases (NDMs) was developed.

    Authors: Tatsuya Tada, Jun-ichiro Sekiguchi, Shin Watanabe, Kyoko Kuwahara-Arai, Naeko Mizutani, Izumi Yanagisawa, Tomomi Hishinuma, Khin Nyein Zan, San Mya, Htay Htay Tin and Teruo Kirikae

    Citation: BMC Infectious Diseases 2019 19:565

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  13. Content type: Research article

    The increased incidence of drug-resistant TB is a major challenge for effective TB control. Limited therapeutic options and poor treatment outcomes of DR-TB may increase drug-resistance rates. The objective of...

    Authors: Niccolò Riccardi, Riccardo Alagna, Laura Saderi, Maurizio Ferrarese, Paola Castellotti, Ester Mazzola, Saverio De Lorenzo, Pietro Viggiani, Zarir Udwadia, Giorgio Besozzi, Daniela Cirillo, Giovanni Sotgiu and Luigi Codecasa

    Citation: BMC Infectious Diseases 2019 19:564

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  14. Content type: Research article

    Rapid and accurate diagnosis of childhood tuberculosis (TB) is challenging because children are often unable to produce the sputum sample required for conventional tests. Stool is an alternative sample type th...

    Authors: Annelies W. Mesman, Martin Soto, Julia Coit, Roger Calderon, Juan Aliaga, Nira R. Pollock, Milagros Mendoza, Francisco M. Mestanza, Carlos J. Mendoza, Megan B. Murray, Leonid Lecca, Rebecca Holmberg and Molly F. Franke

    Citation: BMC Infectious Diseases 2019 19:563

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  15. Content type: Research article

    The proportion of older HIV-1 infected people in China has increased rapidly in recent years. Elucidation of the transmission characteristics of this high-risk population subgroup is helpful for the developmen...

    Authors: Jianjun Wu, Yu Zhang, Yuelan Shen, Xiaolin Wang, Hui Xing, Xiaohui Yang, Xinping Ding, Bing Hu, Hanping Li, Jingwan Han, Jingyun Li, Bin Su, Yongjian Liu and Lin Li

    Citation: BMC Infectious Diseases 2019 19:562

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  16. Content type: Research article

    In a context of increasing use of Nucleic Acid Amplification Test, diagnoses of Neisseria gonorrhoeae and Chlamydia trachomatis infections among men increased in Europe and USA since 2007. We aimed to describe tr...

    Authors: Louise Rossignol, Laurianne Feuillepain, Ndeindo Ndeikoundam Ngangro, Cécile Souty, Nelly Fournet, Yann Le Strat, Noémie Baroux, Thomas Hanslik, Florence Lot and Thierry Blanchon

    Citation: BMC Infectious Diseases 2019 19:561

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  17. Content type: Research article

    Acute meningitis and encephalitis syndromes (AMES) is a severe neurological infection which causes high case fatality and severe sequelae in children. To determine the etiology of childhood AMES in Shenzhen, a...

    Authors: Hongwei Shen, Chunqing Zhu, Xiaorong Liu, Dongli Ma, Chunli Song, Lintao Zhou, Zuer Wang, Yongxuan Ou, Wen Ma, Xianghui Shi, Xuejun Ma and Yiwen Zhou

    Citation: BMC Infectious Diseases 2019 19:560

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  18. Content type: Research article

    Blood smear microscopy remains the gold-standard method to diagnose and quantify malaria parasite density. In addition, parasite genotyping of select loci is the most utilized method for distinguishing recrude...

    Authors: Aine Lehane, Moses Were, Martina Wade, Musleehat Hamadu, Megan Cahill, Sylvia Kiconco, Richard Kajubi, Francesca Aweeka, Norah Mwebaza, Fangyong Li and Sunil Parikh

    Citation: BMC Infectious Diseases 2019 19:559

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  19. Content type: Research article

    Amphotericin-induced phlebitis is a common infusion-related reaction in patients managed for cryptococcal meningitis. High-quality nursing care is critical component to successful cryptococcosis treatment. We ...

    Authors: Cynthia Ahimbisibwe, Richard Kwizera, Jane Frances Ndyetukira, Florence Kugonza, Alisat Sadiq, Kathy Huppler Hullsiek, Darlisha A. Williams, Joshua Rhein, David R. Boulware and David B. Meya

    Citation: BMC Infectious Diseases 2019 19:558

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  20. Content type: Correction


    Authors: Elisabeth Anne-Sophie Mayrhuber, Wim Peersman, Nina van de Kraats, Goranka Petricek, Asja Ćosić Divjak, Silvia Wojczewski and Kathryn Hoffmann

    Citation: BMC Infectious Diseases 2019 19:557

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    The original article was published in BMC Infectious Diseases 2018 18:647

  21. Content type: Research article

    In recent decades, Mycobacterium tuberculosis with the RDRio genotype, frequently isolated from tuberculosis patients in Rio de Janeiro, has become part of the Latin American – Mediterranean (LAM) family and has ...

    Authors: Isabela Neves de Almeida, Sidra Ezidio Gonçalves Vasconcellos, Lida Jouca de Assis Figueredo, Nayanne Gama Teixeira Dantas, Cláudio José Augusto, João Paulo Amaral Hadaad, Philip Noel Suffys, Wânia da Silva Carvalho and Silvana Spíndola de Miranda

    Citation: BMC Infectious Diseases 2019 19:556

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  22. Content type: Research article

    Among people living with HIV (PLWH), the prevalence of non-HIV related co-morbidities is increasing. Aim of the present study is to describe co-morbidity and multi-morbidity, their clustering mode and the pote...

    Authors: Paolo Maggi, Carmen R. Santoro, Marco Nofri, Elena Ricci, Nicolò De Gennaro, Chiara Bellacosa, Elisabetta Schiaroli, Giancarlo Orofino, Barbara Menzaghi, Antonio Di Biagio, Nicola Squillace, Daniela Francisci, Francesca Vichi, Chiara Molteni, Paolo Bonfanti, Giovanni Battista Gaeta…

    Citation: BMC Infectious Diseases 2019 19:555

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  23. Content type: Research article

    Kazakhstan remains a high-burden TB prevalence country with a concomitent high-burden of multi-drug resistant tuberculosis. For this reason, we performed an in depth genetic diversity and population structure cha...

    Authors: B. J. Klotoe, S. Kacimi, E. Costa-Conceicão, H. M. Gomes, R. B. Barcellos, S. Panaiotov, D. Haj Slimene, N. Sikhayeva, S. Sengstake, A. R. Schuitema, M. Akhalaia, A. Alenova, E. Zholdybayeva, P. Tarlykov, R. Anthony, G. Refrégier…

    Citation: BMC Infectious Diseases 2019 19:553

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  24. Content type: Research article

    Human papillomavirus (HPV) is the most widespread sexually transmitted infection worldwide. It causes several health consequences, in particular accounting for the majority of cervical cancer cases in women. I...

    Authors: Samik Datta, Joshua Pink, Graham F. Medley, Stavros Petrou, Sophie Staniszewska, Martin Underwood, Pam Sonnenberg and Matt J. Keeling

    Citation: BMC Infectious Diseases 2019 19:552

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  25. Content type: Research article

    At the end of March 2018, a clustered outbreak of measles associated with health care workers occurred in northern Taiwan. Prior to this study, the policy for measles vaccination for physicians and nurses in M...

    Authors: Chang-Pan Liu, Hsi-Peng Lu and Tainyi Luor

    Citation: BMC Infectious Diseases 2019 19:551

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  26. Content type: Case report

    Sofosbuvir is the keystone of direct antiviral agents for the chronic hepatitis C (CHC). The safety of sofosbuvir in patients with stage 4–5 chronic kidney disease (CKD) needs further observation in real world.

    Authors: Taotao Yan, Jiuping Wang, Juan Li, Shan Fu, Yi Chen, Chunhua Hu, Rou Zhang, Zhen Tian, Fahui Zhao, Jun Dong, Jinfeng Liu, Yuan Yang, Tianyan Chen, Yingren Zhao and Yingli He

    Citation: BMC Infectious Diseases 2019 19:550

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  27. Content type: Research article

    Intestinal parasitic infections are still common in low-income countries including Ethiopia, particularly in children due to low-quality drinking water, poor personal and environmental sanitation. Disabled ind...

    Authors: Agumas Ayalew Fentahun, Anemaw Asrat, Abebayehu Bitew and Selamawit Mulat

    Citation: BMC Infectious Diseases 2019 19:549

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  28. Content type: Research article

    This retrospective study evaluated the performance of a lipoarabinomannan (LAM)-based immunological method for diagnosing pleural tuberculosis (TB) from pleural effusion samples. Results were compared to those...

    Authors: Qingtao Liang, Yu Pang, Yang Yang, Hua Li, Chao Guo, Xinting Yang and Xiaoyou Chen

    Citation: BMC Infectious Diseases 2019 19:548

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  29. Content type: Research article

    A nationwide investigation on the carriage proportion of H. influenzae among healthy populations is lacking in China. The purpose of the study was to review the prevalence of pharyngeal carriage of H. influenzae ...

    Authors: Peng Yang, Jieming Zhang and Anlin Peng

    Citation: BMC Infectious Diseases 2019 19:547

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  30. Content type: Research article

    The effectiveness of Helicobacter pylori first-line treatment has decreased drastically with the rise of strains resistant to clarithromycin. Therapy failure has also been described in patients with infections by...

    Authors: Betsy Verónica Arévalo-Jaimes, Diana F. Rojas-Rengifo, Carlos Alberto Jaramillo, Belén Mendoza de Molano, José Fernando Vera-Chamorro and María del Pilar Delgado

    Citation: BMC Infectious Diseases 2019 19:546

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  31. Content type: Research article

    The role of health literacy on tuberculosis patients has not been evaluated in China, in part because few special health literacy measurements exist.

    Authors: Yan Li, Shaoru Zhang, Tianhua Zhang, Yi Cao, Weiping Liu, Hualin Jiang, Dan Ren, Jing Ren, Haini Liu and Zhongqiu Hua

    Citation: BMC Infectious Diseases 2019 19:545

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  32. Content type: Research article

    Bedaquiline was recently introduced into World Health Organization (WHO)-recommended regimens for treatment of drug resistant tuberculosis. There is limited data on the long-term safety of bedaquiline. Because...

    Authors: Jackie Jones, Vanessa Mudaly, Jacqueline Voget, Tracey Naledi, Gary Maartens and Karen Cohen

    Citation: BMC Infectious Diseases 2019 19:544

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  33. Content type: Case report

    Cysticercosis is an emerging and neglected tropical disease (NTD) that poses a serious public health concern worldwide. Disseminated cysticercosis (DCC) is an uncommon manifestation of cysticercosis, also foun...

    Authors: Yang Zou, Fei Wang, Hong-Bin Wang, Wayne W. Wu, Chia-Kwung Fan, Han-Yu Zhang, Lei Wang, Xiao-Jun Tian, Wei Li and Min-Jun Huang

    Citation: BMC Infectious Diseases 2019 19:543

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  34. Content type: Research article

    Tuberculosis rapid molecular assays, including GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit®, are highly sensitive and specific. Such performance does not automatically translate in improved disease contr...

    Authors: Niaina Rakotosamimanana, Simon Grandjean Lapierre, Vaomalala Raharimanga, Mamy Serge Raherison, Astrid M. Knoblauch, Antso Hasina Raherinandrasana, Andrianantenaina Rakotoson, Julio Rakotonirina and Voahangy Rasolofo

    Citation: BMC Infectious Diseases 2019 19:542

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  35. Content type: Debate

    Hepatitis E is a liver disease caused by a small RNA virus known as hepatitis E virus (HEV). Four major genotypes infect humans, of which genotype 1 and 2 (HEV-1, HEV-2) are endemic mainly in Asia and responsi...

    Authors: Joachim Denner, Sven Pischke, Eike Steinmann, Johannes Blümel and Dieter Glebe

    Citation: BMC Infectious Diseases 2019 19:541

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  36. Content type: Research article

    There is a pressing need for systematic approaches for monitoring how much TB treatment is ongoing in the private sector in India: both to cast light on the true scale of the problem, and to help monitor the p...

    Authors: Nimalan Arinaminpathy, Deepak Batra, Nilesh Maheshwari, Kishan Swaroop, Lokesh Sharma, Kuldeep Singh Sachdeva, Sunil Khaparde, Raghuram Rao, Devesh Gupta, Bhavin Vadera, Sreenivas A. Nair, Kiran Rade, Sameer Kumta and Puneet Dewan

    Citation: BMC Infectious Diseases 2019 19:539

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  37. Content type: Research article

    Group B Streptococcus (GBS) is an important pathogen that causes high mortality and morbidity in young infants. However, data on clinical manifestations between different GBS serotypes and correlation with mol...

    Authors: Yi Kao, Ming-Horng Tsai, Mei-Yin Lai, Shih-Ming Chu, Hsuan-Rong Huang, Ming-Chou Chiang, Ren-Huei Fu, Jang-Jih Lu and Jen-Fu Hsu

    Citation: BMC Infectious Diseases 2019 19:538

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  38. Content type: Research article

    Treatment failure has become a significant challenge in patients taking antiretroviral therapy (ART). The aim of the present study was to identify risk factors for first-line ART failure among patients attendi...

    Authors: Yihienew Mequanint Bezabih, Fekadu Beyene and Woldesellassie M. Bezabhe

    Citation: BMC Infectious Diseases 2019 19:537

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  39. Content type: Research article

    Enterobius vermicularis (pinworm) is one of the most common human parasitic helminths, and children are the most susceptible group. Some behavioral and environmental factors may facilitate pinworm infection. In t...

    Authors: Chia-Kwung Fan, Ting-Wu Chuang, Ying-Chieh Huang, Ai-Wen Yin, Chia-Mei Chou, Yu-Ting Hsu, Ramson Kios, Shao-Lun Hsu, Ying-Ting Wang, Mai-Szu Wu, Jia-Wei Lin, Kennar Briand and Chia-Ying Tu

    Citation: BMC Infectious Diseases 2019 19:536

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  40. Content type: Case report

    Cysticercosis is spreading all over the world and it is a major health problem in most countries of Latin America, Africa, and Asia. Extensive disseminated cysticercosis is relatively rare and fewer than 120 c...

    Authors: Xin-Zhong Zang, Huan-Zhang Li, Men-Bao Qian, Ying-Dan Chen, Chang-Hai Zhou, Hong-Kun Liu, Yu-Hua Liu and Shi-Zhu Li

    Citation: BMC Infectious Diseases 2019 19:535

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  41. Content type: Research article

    Late presentation to HIV/AIDS care which is attended by problems like, poor treatment outcomes, early development of opportunistic infections, increased healthcare costs, and mortality is a major problem in Et...

    Authors: Getaneh Mulualem Belay, Aklilu Endalamaw and Amare Demsie Ayele

    Citation: BMC Infectious Diseases 2019 19:534

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  42. Content type: Research article

    Distribution of Hepatitis C virus (HCV) genotypes varies significantly worldwide. Genomic diversity between genotypes has implications for treatment, vaccine development and optimal design of HCV diagnostic as...

    Authors: Nicholas Israel Nii-Trebi, Charles Addoquaye Brown, Yaa Difie Osei, William Kwabena Ampofo and Alexander Kwadwo Nyarko

    Citation: BMC Infectious Diseases 2019 19:533

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  43. Content type: Research article

    There is controversy regarding the relative influence of ‘exogenous’ versus ‘endogenous’ factors on the risk of progression from latent tuberculosis infection to active tuberculosis (TB) disease in children.

    Authors: Davaasambuu Ganmaa, Polyna Khudyakov, Uyanga Buyanjargal, Delgerekh Baigal, Munkhzul Baatar, Nomin Enkhamgalan, Sumiya Erdenebaatar, Batbayar Ochirbat, Buyankhishig Burneebaatar, Enkhtamir Purevdorj, Yanjindulam Purevsuren, Gantsetseg Garmaa, Erdenetuya Ganbaatar and Adrian R. Martineau

    Citation: BMC Infectious Diseases 2019 19:532

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  44. Content type: Research article

    Clinical microbiology laboratories are asked to process large numbers of urine specimens for culture, but only 20–40% of them are positive. Therefore, a rapid, reliable screening method is necessary to speed u...

    Authors: Jong-Mi Lee, Doo-Jin Baek, Kang Gyun Park, Eunhee Han and Yeon-Joon Park

    Citation: BMC Infectious Diseases 2019 19:531

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  45. Content type: Case report

    Infective endocarditis (IE) caused by gram-negative bacilli is rare. However, the incidence of this severe infection is rising because of the increasing number of persons at risk, such as patients with immunos...

    Authors: Nicolas Gürtler, Michael Osthoff, Florian Rueter, Daniel Wüthrich, Lukas Zimmerli, Adrian Egli and Stefano Bassetti

    Citation: BMC Infectious Diseases 2019 19:530

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  46. Content type: Case report

    Tuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretrovir...

    Authors: Gopalan Narendran, Deivide Oliveira-de-Souza, Caian L. Vinhaes, Kevan Akrami, Kiyoshi F. Fukutani, Kesavamurthy Banu, Padmapriyadarsini Chandrasekaran, Narayanan Ravichandran, Irini Sereti, Soumya Swaminathan and Bruno B. Andrade

    Citation: BMC Infectious Diseases 2019 19:529

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  47. Content type: Research article

    Several factors have been identified as being associated with increased adherence to antiretroviral therapy, including sero-status disclosure; however, studies examining the effect of disclosure on ART adheren...

    Authors: Getenet Dessie, Fasil Wagnew, Henok Mulugeta, Dessalegn Amare, Dube Jara, Cheru Tesema Leshargie, Ayenew Negesse, Swati Rayasam and Sahai Burrowes

    Citation: BMC Infectious Diseases 2019 19:528

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