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  1. The emergence and spread of Carbapenem-resistant Escherichia coli (CREC) is becoming a serious problem in Chinese hospitals, however, the data on this is scarce. Therefore, we investigate the risk factors for hea...

    Authors: Xiujuan Meng, Sidi Liu, Juping Duan, Xun Huang, Pengcheng Zhou, Xinrui Xiong, Ruie Gong, Ying Zhang, Yao Liu, Chenchao Fu, Chunhui Li and Anhua Wu
    Citation: BMC Infectious Diseases 2017 17:82
    Content type: Research article Published on:

  2. Cocaine and crack use has been associated with HIV and HCV infections, but its consequences on HCV progression have not been well established. We analyzed the impact of cocaine/crack use on liver fibrosis prog...

    Authors: Valérie Martel-Laferrière, Roy Nitulescu, Joseph Cox, Curtis Cooper, Mark Tyndall, Danielle Rouleau, Sharon Walmsley, Leo Wong and Marina B. Klein
    Citation: BMC Infectious Diseases 2017 17:80
    Content type: Research article Published on:

  3. Carbapenemase-producing Enterobacteriaceae (CPE) are difficult to identify among carbapenem non-susceptible Enterobacteriaceae (NSE). We designed phenotypic strategies giving priority to high sensitivity for s...

    Authors: Jérôme Robert, Alix Pantel, Audrey Merens, Elodie Meiller, Jean-Philippe Lavigne and Marie-Hélène Nicolas-Chanoine
    Citation: BMC Infectious Diseases 2017 17:78
    Content type: Research article Published on:

  4. Tuberculous lymphadenitis (TBLN) diagnosis has been a true challenge solely by clinical evidence in developing countries, due to limited the diagnostic facility on hand. However, the availability and affordabi...

    Authors: Olifan Zewdie, Tamrat Abebe, Adane Mihret, Eyob Hirpa and Gobena Ameni
    Citation: BMC Infectious Diseases 2017 17:77
    Content type: Research article Published on:

  5. Toll like receptors (TLRs) play an important role in innate immunity and various studies suggest that TLRs play a crucial role in pathogenesis of hepatitis B virus (HBV) infection. The present study aims in lo...

    Authors: Dipanwita Das, Isha Sengupta, Neelakshi Sarkar, Ananya Pal, Debraj Saha, Manikankana Bandopadhyay, Chandrima Das, Jimmy Narayan, Shivaram Prasad Singh, Sekhar Chakrabarti and Runu Chakravarty
    Citation: BMC Infectious Diseases 2017 17:76
    Content type: Research article Published on:

  6. Daily bathing with chlorhexidine gluconate (CHG) of intensive care unit (ICU) patients has been shown to reduce healthcare-associated infections and colonization by multidrug resistant organisms. The objective...

    Authors: Jackson S. Musuuza, Tonya J. Roberts, Pascale Carayon and Nasia Safdar
    Citation: BMC Infectious Diseases 2017 17:75
    Content type: Research article Published on:

  7. Current prevention options for upper respiratory infections (URIs) are not optimal. We conducted a randomized, double-blinded, placebo-controlled pilot clinical trial to evaluate the safety and efficacy of ARM...

    Authors: Pranab K. Mukherjee, Frank Esper, Ken Buchheit, Karen Arters, Ina Adkins, Mahmoud A. Ghannoum and Robert A. Salata
    Citation: BMC Infectious Diseases 2017 17:74
    Content type: Research article Published on:

  8. Cervical cancer is the leading cause of cancer morbidity and mortality among women in Nepal and Bhutan. Data on high-risk human papillomavirus (HR-HPV) infection and cervical abnormalities among Nepali and Bhu...

    Authors: Madhav P. Bhatta, Derek C. Johnson, Mingma Lama, Shilu Aryal, Pema Lhaki and Sadeep Shrestha
    Citation: BMC Infectious Diseases 2017 17:73
    Content type: Research article Published on:

  9. Scedosporium apiospermum, which can usually be isolated from soil, polluted stream water and decaying vegetation, is increasingly recognized as an opportunistic dematiaceous fungus. Th...

    Authors: Choon-Mee Kim, Sung-Chul Lim, Joa Kim, Hoe-Soo Jang, Jong-Hun Chung, Na-Ra Yun, Dong-Min Kim, Piyush Jha, Babita Jha, Seok Won Kim, Sook Jin Jang and Jong Hee Shin
    Citation: BMC Infectious Diseases 2017 17:72
    Content type: Case report Published on:

  10. The primary unit of tuberculosis (TB) medical care in China is the county TB dispensary or county designated hospital (CTD), where patients can receive free diagnosis and treatment. However, a substantial numb...

    Authors: Li Yuan, Hui Zhang, Changming Zhou, Weili Jiang, Qi Zhao and Xu Biao
    Citation: BMC Infectious Diseases 2017 17:71
    Content type: Research article Published on:

  11. Tumor necrosis factor antagonist inhibitors have transformed the approach to patients with severe autoimmune conditions, such as rheumatoid arthritis. Although the therapy can be highly effective, TNF-α inhibi...

    Authors: Juan E. Muñoz-Oca, Martha L. Villarreal Morales, Aracelis Nieves-Rodriguez and Lemuel Martínez-Bonilla
    Citation: BMC Infectious Diseases 2017 17:70
    Content type: Case report Published on:

  12. Around 30% of the population will experience herpes zoster (HZ), 10% of whom develop postherpetic neuralgia (PHN). Together, these illnesses produce a significant economic burden to the healthcare system.

    Authors: Kevin J. Friesen, Dan Chateau, Jamie Falk, Silvia Alessi-Severini and Shawn Bugden
    Citation: BMC Infectious Diseases 2017 17:69
    Content type: Research article Published on:

  14. To date more than 20 antigenically distinct strains of Orientia tsutsugamushi (OT) reported within the tsutsugamushi triangle that cause an undifferentiated acute febrile illness in humans. Genotypic characteriza...

    Authors: Ranjan Premaratna, Lucas S. Blanton, Dilhar N. Samaraweera, G. Nalika N. de Silva, Nilmini T. G. A. Chandrasena, David H. Walker and H. J. de Silva
    Citation: BMC Infectious Diseases 2017 17:67
    Content type: Research article Published on:

  15. HIV-infected patients may present an unforeseen clinical worsening after initiating antiretroviral therapy known as immune reconstitution inflammatory syndrome (IRIS). This syndrome is characterized by a heigh...

    Authors: Rita Rb-Silva, Claudia Nobrega, Eugénia Reiriz, Soraia Almeida, Rui Sarmento-Castro, Margarida Correia-Neves and Ana Horta
    Citation: BMC Infectious Diseases 2017 17:66
    Content type: Case report Published on:

  16. An international spread of Zika virus (ZIKV) infection has attracted global attention in 2015. The infection also affected Guangdong province, which is located in southern China. Multiple factors, including fr...

    Authors: Xing Li, Tao Liu, Lifeng Lin, Tie Song, Xiaolong Du, Hualiang Lin, Jianpeng Xiao, Jianfeng He, Liping Liu, Guanghu Zhu, Weilin Zeng, Lingchuan Guo, Zheng Cao, Wenjun Ma and Yonghui Zhang
    Citation: BMC Infectious Diseases 2017 17:65
    Content type: Research article Published on:

  17. Authors: I. Rivero-Calle, J. Pardo-Seco, P. Aldaz, D. A. Vargas, E. Mascarós, E. Redondo, J. L. Díaz-Maroto, M. Linares-Rufo, M. J. Fierro-Alacio, A. Gil, J. Molina, D. Ocaña and Federico Martinón-Torres
    Citation: BMC Infectious Diseases 2017 17:64
    Content type: Erratum Published on:

    The original article was published in BMC Infectious Diseases 2016 16:645

  18. Bacterial resistance to antibiotics is an increasingly threatening consequence of antimicrobial exposure for many decades now. In urinary tract infections (UTIs), antibiotic prophylaxis (AP) increases bacteria...

    Authors: Sebastiaan Hermanus Johannes Zegers, Jeanne Dieleman, Tjomme van der Bruggen, Jan Kimpen and Catharine de Jong-de Vos van Steenwijk
    Citation: BMC Infectious Diseases 2017 17:63
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Infectious Diseases 2017 17:175

  19. The number of viral pathogens associated with pediatric acute respiratory tract infection (ARI) has grown since the introduction of reverse transcription real-time polymerase chain reaction (RT-PCR) assays. Mu...

    Authors: Jérôme O. Wishaupt, Tjeerd van der Ploeg, Ronald de Groot, Florens G. A. Versteegh and Nico G. Hartwig
    Citation: BMC Infectious Diseases 2017 17:62
    Content type: Research article Published on:

  20. Chronic HIV infection is associated with low-level inflammation and increased risk of chronic diseases and mortality. The objective was to assess the effects of moderate intensity exercise on metabolic and inf...

    Authors: Matteo Bonato, Laura Galli, Laura Passeri, Valeria Longo, Gaspare Pavei, Simona Bossolasco, Cecilia Bertocchi, Massimo Cernuschi, Giuseppe Balconi, Giampiero Merati, Adriano Lazzarin, Antonio La Torre and Paola Cinque
    Citation: BMC Infectious Diseases 2017 17:61
    Content type: Research article Published on:

  21. We evaluated the performance of the Becton Dickinson Veritorâ„¢ System Flu A + B rapid influenza diagnostic test (RIDT) to detect influenza viruses in respiratory specimens from patients enrolled at five surveil...

    Authors: Linus K. Ndegwa, Gideon Emukule, Timothy M. Uyeki, Eunice Mailu, Sandra S. Chaves, Marc-Alain Widdowson, Bandika V. Lewa, Francis K. Muiruri, Peter Omoth, Barry Fields and Joshua A. Mott
    Citation: BMC Infectious Diseases 2017 17:60
    Content type: Research article Published on:

  22. Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite with a broad host range including most warm-blooded animals, including humans. T. gondii surface antigen 1...

    Authors: Yali Han, Aihua Zhou, Gang Lu, Guanghui Zhao, Lin Wang, Jingjing Guo, Pengxia Song, Jian Zhou, Huaiyu Zhou, Hua Cong and Shenyi He
    Citation: BMC Infectious Diseases 2017 17:59
    Content type: Research article Published on:

  23. Bidirectional signalling between the brain and the gastrointestinal tract is regulated at neural, hormonal, and immunological levels. Recent studies have shown that helminth infections can alter the normal gut...

    Authors: Vanina Guernier, Bradley Brennan, Laith Yakob, Gabriel Milinovich, Archie C. A. Clements and Ricardo J. Soares Magalhaes
    Citation: BMC Infectious Diseases 2017 17:58
    Content type: Debate Published on:

  24. Surveillance data on the proportion of incident TB cases with MDR was limited and there is no systematic study of MDR-TB in China to date. Our aim was to estimate MDR-TB disease burden in 2012 and change trend...

    Authors: Peipei Ding, Xiaowen Li, Zhongwei Jia and Zuhong Lu
    Citation: BMC Infectious Diseases 2017 17:57
    Content type: Research article Published on:

  25. Mumps emerged among highly vaccinated populations in the Netherlands. This offered a unique opportunity to study mumps virus transmission. In particular the extent to which asymptomatic infections in vaccinate...

    Authors: Susan Hahné, Tessa Schurink, Jacco Wallinga, Jeroen Kerkhof, Marianne van der Sande, Rob van Binnendijk and Hester de Melker
    Citation: BMC Infectious Diseases 2017 17:56
    Content type: Research article Published on:

  26. The magnitude of the current Zika virus (ZIKV) epidemic has led to a declaration of a Public Health Emergency of International Concern by the WHO. Findings of viable viral particles in semen for several weeks ...

    Authors: Guenter Froeschl, Kristina Huber, Frank von Sonnenburg, Hans-Dieter Nothdurft, Gisela Bretzel, Michael Hoelscher, Lothar Zoeller, Matthias Trottmann, Francisco Pan-Montojo, Gerhard Dobler and Silke Woelfel
    Citation: BMC Infectious Diseases 2017 17:55
    Content type: Case report Published on:

  27. People living with human immunodeficiency virus (HIV) who have not yet initiated antiretroviral therapy (ART) can benefit from being engaged in care and utilizing preventive interventions. Community-based peer...

    Authors: April Monroe, Gertrude Nakigozi, William Ddaaki, Jeremiah Mulamba Bazaale, Ronald H. Gray, Maria J. Wawer, Steven J. Reynolds, Caitlin E. Kennedy and Larry W. Chang
    Citation: BMC Infectious Diseases 2017 17:54
    Content type: Research article Published on:

  28. Urinary and (peripheral and central) intravenous catheters are widely used in hospitalized patients. However, up to 56% of the catheters do not have an appropriate indication and some serious complications wit...

    Authors: Bart J. Laan, Ingrid J. B. Spijkerman, Mieke H. Godfried, Berend C. Pasmooij, Jolanda M. Maaskant, Marjon J. Borgert, Brent C. Opmeer, Margreet C. Vos and Suzanne E. Geerlings
    Citation: BMC Infectious Diseases 2017 17:53
    Content type: Study protocol Published on:

  29. To determine the cost-effectiveness of strategies of preferred antibiotic treatment with beta-lactam/macrolide combination or fluoroquinolone monotherapy compared to beta-lactam monotherapy.

    Authors: Cornelis H. van Werkhoven, Douwe F. Postma, Marie-Josee J. Mangen, Jan Jelrik Oosterheert and Marc J. M. Bonten
    Citation: BMC Infectious Diseases 2017 17:52
    Content type: Research article Published on:

  30. The incidence of cryptococcal meningitis (CM) and tuberculous meningitis (TBM) have gradually increased in recent years. These two types of meningitis are easily misdiagnosed which leads to a poor prognosis. I...

    Authors: Junyan Qu, Taoyou Zhou, Cejun Zhong, Rong Deng and Xiaoju Lü
    Citation: BMC Infectious Diseases 2017 17:51
    Content type: Research article Published on:

  32. Sri Lanka achieved the WHO certificate as a malaria free country in September 2016, thus monitoring of malaria transmission using sensitive and effective tools is an important need. Use of age-specific antibod...

    Authors: Rajika Lasanthi Dewasurendra, Janaka Nandana Dias, Nuno Sepulveda, Geethika Sharmini Abayaweera Gunawardena, Naduviladath Chandrasekharan, Chris Drakeley and Nadira Dharshani Karunaweera
    Citation: BMC Infectious Diseases 2017 17:49
    Content type: Research article Published on:

  34. Variable exposure to causative agents of acute respiratory (RTI) or gastrointestinal tract infections (GTI) is a significant confounding factor in the analysis of the efficacy of interventions concerning these...

    Authors: Tapani Hovi, Jukka Ollgren and Carita Savolainen-Kopra
    Citation: BMC Infectious Diseases 2017 17:47
    Content type: Research article Published on:

  35. Previous studies have discussed the overlapping and reinforcing effects (defined as a syndemic) of psychosocial problems on high-risk sexual behaviors among men who have sex with men (MSM). The present study a...

    Authors: Ying Wang, Zezhou Wang, Mengmeng Jia, Ajuan Liang, Dong Yuan, Zhe Sun, Feng Gan, Yichen Wang, Yong Cai and Zhiruo Zhang
    Citation: BMC Infectious Diseases 2017 17:46
    Content type: Research article Published on:

  36. There is limited evidence for the effectiveness of daclatasvir in patients whose hepatitis C threatens their life expectancy. The Named Patient Program in Europe included patients with advanced chronic hepatit...

    Authors: Jim Young, Nina Weis, Harald Hofer, William Irving, Ola Weiland, Emiliano Giostra, Juan Manuel Pascasio, Lluis Castells, Martin Prieto, Roelien Postema, Cinira Lefevre, David Evans, Heiner C. Bucher and Jose Luis Calleja
    Citation: BMC Infectious Diseases 2017 17:45
    Content type: Research article Published on:

  37. Cefotaxime plays an important role in the treatment of patients with bacteremia due to Enterobacteriaceae, although cefotaxime resistance is reported to be increasing in association with extended-spectrum β-lacta...

    Authors: Taro Noguchi, Yasufumi Matsumura, Masaki Yamamoto, Miki Nagao, Shunji Takakura and Satoshi Ichiyama
    Citation: BMC Infectious Diseases 2017 17:44
    Content type: Research article Published on:

  38. Statin use is associated with a modest increase in the incidence of type 2 diabetes mellitus (DM) among the general population. However, HIV-infected patients have a higher risk of developing DM, and it is unc...

    Authors: Vincenzo Spagnuolo, Laura Galli, Andrea Poli, Stefania Salpietro, Nicola Gianotti, Piermarco Piatti, Francesca Cossarini, Concetta Vinci, Elisabetta Carini, Adriano Lazzarin and Antonella Castagna
    Citation: BMC Infectious Diseases 2017 17:43
    Content type: Research article Published on:

  39. Severe fever with thrombocytopenia syndrome (SFTS) is an emerging epidemic infectious disease with high mortality in East Aisa, especially in China. To predict the prognosis of SFTS precisely is important in c...

    Authors: Li Wang, Zhiqiang Zou, Chunguo Hou, Xiangzhong Liu, Fen Jiang and Hong Yu
    Citation: BMC Infectious Diseases 2017 17:42
    Content type: Research article Published on:

  40. There is growing evidence of an interaction between HIV-infection, anti-retroviral therapy (ART) and cardiovascular diseases (CVD). Epidemiological studies in Europe and North America have been observing a shi...

    Authors: Hans Strijdom, Patrick De Boever, Gerhard Walzl, M. Faadiel Essop, Tim S. Nawrot, Ingrid Webster, Corli Westcott, Nyiko Mashele, Frans Everson, Stephanus T. Malherbe, Kim Stanley, Harald H. Kessler, Evelyn Stelzl and Nandu Goswami
    Citation: BMC Infectious Diseases 2017 17:41
    Content type: Study protocol Published on:

  41. There have been various reports concerning Helicobacter cinaedi infections. However, few reports have examined central nervous system infections.

    Authors: Toshimasa Hayashi, Junko Tomida, Yoshiaki Kawamura, Masakazu Yoshida, Ikuyo Yokozawa and Shingaku Kaneko
    Citation: BMC Infectious Diseases 2017 17:40
    Content type: Case report Published on:

  42. Tedizolid, the active moiety of tedizolid phosphate, is approved in the United States, the European Union, Canada and a number of other countries for the treatment of acute bacterial skin and skin structure in...

    Authors: Rachael McCool, Ian M. Gould, Jacqui Eales, Teresa Barata, Mick Arber, Kelly Fleetwood, Julie Glanville and Teresa L. Kauf
    Citation: BMC Infectious Diseases 2017 17:39
    Content type: Research article Published on:

  43. The clinical features of bacteria endocarditis became atypical when consolidated with other conditions such as tuberculosis (TB). Especially, the symptoms of bacteria endocarditis (BE) which were hidden behind...

    Authors: Yan Liu, Xiaoming Wang, Zhibin Wang, Yongsheng Zhu, Liying Zhang, Xiaoli Li, Rong Xu and Wei Ge
    Citation: BMC Infectious Diseases 2017 17:38
    Content type: Case report Published on:

  44. CCR5 coreceptor using HIV-1 subtype C (HIV-1C) has been reported to dominate the Ethiopian epidemic. However, almost all data have been obtained from two large cities in the central and north-west regions and ...

    Authors: Amare Worku Kalu, Nigus Fikrie Telele, Solomon Gebreselasie, Daniel Fekade, Samir Abdurahman, Gaetano Marrone and Anders Sönnerborg
    Citation: BMC Infectious Diseases 2017 17:37
    Content type: Research article Published on:

  45. Globally 3.9% of new and 21% of re-treatment tuberculosis (TB) cases are multidrug-resistant or rifampicin-resistant (MDR/RR), which is often interpreted as evidence that drug resistance results mainly from po...

    Authors: Romain Ragonnet, James M. Trauer, Justin T. Denholm, Ben J. Marais and Emma S. McBryde
    Citation: BMC Infectious Diseases 2017 17:36
    Content type: Research article Published on:

  46. Rectal infection with Chlamydia trachomatis is one of the most common bacterial sexually transmissible infections among men who have sex with men (MSM) with diagnosis rates continuing to rise. Current treatment g...

    Authors: Andrew Lau, Fabian Kong, Christopher K. Fairley, Basil Donovan, Marcus Chen, Catriona Bradshaw, Mark Boyd, Janaki Amin, Peter Timms, Sepehr Tabrizi, David G. Regan, David A. Lewis, Anna McNulty and Jane S. Hocking
    Citation: BMC Infectious Diseases 2017 17:35
    Content type: Study protocol Published on:

  47. A previous study explored factors discriminating colonization and true infection among non-transplant, non-neutropenic patients with repeated Aspergillus spp. isolation from lower respiratory samples. The present...

    Authors: José Barberán, Francisco-Javier García-Pérez, Victoria Villena, Alberto Fernández-Villar, Eduardo Malmierca, Cristina Salas, María-José Giménez, Juan-José Granizo and Lorenzo Aguilar
    Citation: BMC Infectious Diseases 2017 17:34
    Content type: Research article Published on:

  48. Patients with multiple myeloma are generally immune-compromised either due to pronounced depression in primary antibody responses or because of anti-myeloma therapy. Infection is a major risk factor for early ...

    Authors: Chun-Teng Huang, Chia-Jen Liu, Po-Shen Ko, Han-Tsung Liu, Yuan-Bin Yu, Liang-Tsai Hsiao, Jyh-Pyng Gau, Cheng-Hwai Tzeng, Tzeon-Jye Chiou, Jin-Hwang Liu, Muh-Hwa Yang, Ling-Ju Huang and Chun-Yu Liu
    Citation: BMC Infectious Diseases 2017 17:33
    Content type: Research article Published on:

  49. Rwanda is a central African country with about 12 million inhabitants. The 1994 genocide against the Tutsi destroyed much of the infrastructure, including the health system. Although this has improved signific...

    Authors: Theogene Twagirumugabe, Gatare Swaibu, Timothy David Walker, Magnus Lindh, Jean Bosco Gahutu, Tomas Bergström and Heléne Norder
    Citation: BMC Infectious Diseases 2017 17:32
    Content type: Research article Published on:

  50. Respiratory syncytial virus (RSV) infection is an important cause of hospitalization in previously healthy infants. Immunological mechanisms predisposing infants to severe disease are ...

    Authors: Kiran Aftab Gul, Tonje Sonerud, Hans O. Fjærli, Britt Nakstad, Tore Gunnar Abrahamsen and Christopher S. Inchley
    Citation: BMC Infectious Diseases 2017 17:18
    Content type: Research article Published on:

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BMC Infectious Diseases

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