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  1. The best surgical modality for treating chronic periprosthetic hip infections remains controversial, with a lack of randomised controlled studies. The aim of this systematic review is to compare the infection ...

    Authors: D. A. George, N. Logoluso, G. Castellini, S. Gianola, S. Scarponi, F. S. Haddad, L. Drago and C. L. Romano
    Citation: BMC Infectious Diseases 2016 16:553
    Content type: Research article Published on:

  2. Many nations maintain stockpiles of neuraminidase inhibitor (NAI) antiviral agents for use in influenza pandemics to reduce transmission and mitigate the course of clinical infection. Pandemic preparedness pla...

    Authors: Robert Moss, James M. McCaw, Allen C. Cheng, Aeron C. Hurt and Jodie McVernon
    Citation: BMC Infectious Diseases 2016 16:552
    Content type: Research Article Published on:

  4. This study aims to identify dengue neutralizing antibody response in patients with dengue from a well-characterized cohort during an outbreak in central Brazil, 2012–2013.

    Authors: Angela Ferreira Lopes de Teive e Argolo, Valéria Christina de Rezende Féres, Marli Tenório Cordeiro, Lucimeire Antonelli da Silveira, Adriana Oliveira Guilarde, Ernesto Torres de Azevedo Marques Jr., Wayner Vieira de Souza and Celina Maria Turchi Martelli
    Citation: BMC Infectious Diseases 2016 16:546
    Content type: Research article Published on:

  5. HIV-1 infection impairs tuberculosis (TB) specific immune responses affecting the diagnosis of latent TB. We aimed to (1) determine the proportion of HIV-1-infected adults with a negative QuantiFERON®-TB Gold ...

    Authors: Hanif Esmail, Friedrich Thienemann, Tolu Oni, Rene Goliath, Katalin A. Wilkinson and Robert J. Wilkinson
    Citation: BMC Infectious Diseases 2016 16:545
    Content type: Research article Published on:

  6. E protein of tick-borne encephalitis virus (TBEV) and other flaviviruses is located on the surface of the viral particle. Domain III of this protein seems to be a promising component of subunit vaccines for pr...

    Authors: Anna S. Ershova, Olga A. Gra, Alexander M. Lyaschuk, Tatyana M. Grunina, Artem P. Tkachuk, Mikhail S. Bartov, Darya M. Savina, Olga V. Sergienko, Zoya M. Galushkina, Vladimir P. Gudov, Liubov I. Kozlovskaya, Ivan S. Kholodilov, Larissa V. Gmyl, Galina G. Karganova, Vladimir G. Lunin, Anna S. Karyagina…
    Citation: BMC Infectious Diseases 2016 16:544
    Content type: Research article Published on:

  7. Yemen has witnessed several dengue fever outbreaks coincident with the social unrest and war in the country. The aim of the present study was to describe the knowledge, attitudes and practices (KAPs) of at-ris...

    Authors: Thaker A. A. Alyousefi, Rashad Abdul-Ghani, Mohammed A. K. Mahdy, Samira M. A. Al-Eryani, Abdulsalam M. Al-Mekhlafi, Yahia A. Raja, Shamusul Azhar Shah and John C. Beier
    Citation: BMC Infectious Diseases 2016 16:543
    Content type: Research article Published on:

  8. In 2010, a universal nomenclature for varicella-zoster virus (VZV) clades was established, which is very useful in the monitoring of viral evolution, recombination, spread and genetic diversity. Currently, inf...

    Authors: Songtao Xu, Mukai Chen, Huanying Zheng, Haiyan Wang, Meng Chen, Jianhui Zhou, Wang Shuang, Pengbo Yu, Chaofeng Ma, Jilan He, Daxing Feng, Zhu Zhen, Zhang Yan, Mao Naiying, Aili Cui, Qiuhua Wu…
    Citation: BMC Infectious Diseases 2016 16:542
    Content type: Research article Published on:

  9. Coxiella burnetii is an important zoonotic pathogen of global distribution. Still, in most parts of South America including Chile, systematic epidemiological data are lacking. The presented study aims to determin...

    Authors: Thomas Weitzel, Javier López, Gerardo Acosta-Jamett, Sophie Edouard, Philippe Parola and Katia Abarca
    Citation: BMC Infectious Diseases 2016 16:541
    Content type: Research article Published on:

  10. Immigrants from countries with high incidence of tuberculosis (TB) are usually offered screening when they arrive to low incidence countries. The tuberculin skin test (TST) is often used. The interferon gamma ...

    Authors: Margret Johansson Gudjónsdóttir, Karsten Kötz, Ruth Stangebye Nielsen, Philip Wilmar, Sofia Olausson, Daniel Wallmyr and Birger Trollfors
    Citation: BMC Infectious Diseases 2016 16:540
    Content type: Research article Published on:

  11. New methods for controlling sand fly are highly desired by the Visceral Leishmaniasis (VL) elimination program of Bangladesh, India and Nepal for its consolidation and maintenance phases. To support the progra...

    Authors: M. Mamun Huda, Vijay Kumar, Murari Lal Das, Debashis Ghosh, Jyoti Priyanka, Pradeep Das, Abdul Alim, Greg Matlashewski, Axel Kroeger, Eduardo Alfonso-Sierra and Dinesh Mondal
    Citation: BMC Infectious Diseases 2016 16:539
    Content type: Research article Published on:

  12. Infections remain a leading cause of morbidity and mortality among liver transplant (LT) recipients. The aim of our study was to define the factors associated with outcome of early bacterial and fungal infecti...

    Authors: Francesco Barchiesi, Roberto Montalti, Pamela Castelli, Daniele Nicolini, Silvia Staffolani, Federico Mocchegiani, Alessandro Fiorentini, Esther Manso and Marco Vivarelli
    Citation: BMC Infectious Diseases 2016 16:538
    Content type: Research article Published on:

  13. Tuberculosis (TB) now ranks alongside HIV as the leading infectious disease cause of death worldwide and incurs a global economic burden of over $12 billion annually. Directly observed therapy (DOT) recommends...

    Authors: Zoë M. McLaren, Amanda A. Milliken, Amanda J. Meyer and Alana R. Sharp
    Citation: BMC Infectious Diseases 2016 16:537
    Content type: Debate Published on:

  14. Carbapenem-resistant Enterobacteriaceae (CRE) is a concern in South Africa and worldwide. It is therefore important that these organisms be accurately identified for infection prevention control purposes.

    Authors: Ashika Singh-Moodley and Olga Perovic
    Citation: BMC Infectious Diseases 2016 16:536
    Content type: Research article Published on:

  15. Beta-haemolytic streptococci are important contributors to the global burden of osteoarticular infections (OAI). Knowledge on the disease traits specific for streptococcal OAI, however, remains scarce. We wish...

    Authors: Oddvar Oppegaard, Steinar Skrede, Haima Mylvaganam and Bård Reiakvam Kittang
    Citation: BMC Infectious Diseases 2016 16:535
    Content type: Research article Published on:

  16. Guangzhou reported its first laboratory-confirmed case of influenza A (H7N9) on January 10, 2014. A total of 25 cases were reported from the first wave of the epidemic until April 8, 2014. The fatality rate wa...

    Authors: Hui Wang, XinCai Xiao, Jianyun Lu, Zongqiu Chen, Kuibiao Li, Hui Liu, Lei Luo, Ming Wang and ZhiCong Yang
    Citation: BMC Infectious Diseases 2016 16:534
    Content type: Research article Published on:

  17. Globally, prison inmates are a high-risk population for tuberculosis (TB), but the specific drivers of disease and impact of mass screening interventions are poorly understood.

    Authors: Dayse Sanchez Guimarães Paião, Everton Ferreira Lemos, Andrea da Silva Santos Carbone, Renata Viebrantz Enne Sgarbi, Alexandre Laranjeira Junior, Fellipe Matos da Silva, Letícia Marques Brandão, Luciana Squarizi dos Santos, Vaneli Silva Martins, Simone Simionatto, Ana Rita Coimbra Motta-Castro, Maurício Antônio Pompílio, Juliana Urrego, Albert Icksang Ko, Jason Randolph Andrews and Julio Croda
    Citation: BMC Infectious Diseases 2016 16:533
    Content type: Research article Published on:

  18. Generic drug policies are often associated with concerns about the quality and effectiveness of these products. Phase IV clinical trials may be a suitable design to assess the effectiveness and safety of gener...

    Authors: Jaime Galindo, Pedro Amariles, Héctor F. Mueses-Marín, Jaime A. Hincapié, Sebastián González-Avendaño and Ximena Galindo-Orrego
    Citation: BMC Infectious Diseases 2016 16:532
    Content type: Research article Published on:

  19. Ordinary screening of transfusion-transmissible infections (TTIs) among blood donors is essential for blood transfusion. Although there is several TTIs studies focus on human immunodeficiency virus, hepatitis ...

    Authors: Shuguo Yang, Danmei Jiao, Changjun Liu, Ming Lv, Shan Li, Zongyun Chen, Yao Deng, Yanqing Zhao and Jian Li
    Citation: BMC Infectious Diseases 2016 16:531
    Content type: Research article Published on:

  20. Parasitic infections affect tens of millions of pregnant women worldwide, and directly or indirectly lead to a spectrum of adverse maternal and fetal/placental effects. The objective of this study was to asses...

    Authors: Adane Derso, Endalkachew Nibret and Abaineh Munshea
    Citation: BMC Infectious Diseases 2016 16:530
    Content type: Research article Published on:

  21. There are increasing data regarding Terrisporobacter glycolicus as an emerging anaerobic pathogen. However, the few published cases to date usually report it as part of a polymicrobial infection. Here, we describ...

    Authors: Matthew P. Cheng, Marc-Christian Domingo, Simon Lévesque and Cedric P. Yansouni
    Citation: BMC Infectious Diseases 2016 16:529
    Content type: Case report Published on:

  22. Pneumocystis jiroveci pneumonia (PJP) in non-HIV patients is still a challenge for intensivists. The aim of our study was to evaluate mortality predictors of PJP patients requiring Intensive care unit (ICU) admis...

    Authors: Li Weng, Xu Huang, Lie Chen, Li-Qin Feng, Wei Jiang, Xiao-Yun Hu, Jin-Min Peng, Chun-Yao Wang, Qing-Yuan Zhan and Bin Du
    Citation: BMC Infectious Diseases 2016 16:528
    Content type: Research article Published on:

  23. We present an extremely rare case of tubo-ovarian abscesses involving Corynebacterium striatum (C. striatum) as causative agent in a 53-year-old woman.

    Authors: Tetsuya Yamamoto, Tsuneaki Kenzaka, Shimpei Mizuki, Yuki Nakashima, Houu Kou, Motoyoshi Maruo and Hozuka Akita
    Citation: BMC Infectious Diseases 2016 16:527
    Content type: Case report Published on:

  24. Longitudinal studies of female sex workers (FSWs) are vulnerable to loss to follow-up (LTFU) due to this population’s high mobility and low willingness to self-identify as FSWs. LTFU in cohort studies is a cri...

    Authors: Yingying Su, Guowei Ding, Kathleen H. Reilly, Jessie L. Norris, Huixin Liu, Zheng Li, Guixiang Wang, Ganggang Fang and Ning Wang
    Citation: BMC Infectious Diseases 2016 16:526
    Content type: Research article Published on:

  25. The Hepatitis Delta Virus (HDV) can increase the incidence of fulminant hepatitis. For this infection occurs, the host must also be infected with Hepatitis B Virus. Previous studies demonstrated the endemicity...

    Authors: Maira Ferreira Cicero, Nathalia Mantovani Pena, Luiz Claudio Santana, Rafael Arnold, Rafael Gonçalves Azevedo, Élcio de Souza Leal, Ricardo Sobhie Diaz and Shirley Vasconcelos Komninakis
    Citation: BMC Infectious Diseases 2016 16:525
    Content type: Research article Published on:

  26. Literature shows inconsistency in meteorological effects on Hand, foot, and mouth disease (HFMD) in different cities. This multi-city study aims to investigate the meteorological effects on pediatric HFMD occu...

    Authors: Cui Guo, Jun Yang, Yuming Guo, Qiao-Qun Ou, Shuang-Quan Shen, Chun-Quan Ou and Qi-Yong Liu
    Citation: BMC Infectious Diseases 2016 16:524
    Content type: Research article Published on:

  27. Malaria is one of the leading causes of morbidity and mortality in children and HIV infection as well as other factors may worsen the situation. This study was aimed at determining the factors influencing mala...

    Authors: Ayukenchengamba Bate, Helen K. Kimbi, Emmaculate Lum, Leopold G. Lehman, Elias F. Onyoh, Lucy M. Ndip, Conica M. Njabi, Calvin Tonga, Godlove B.Wempnje, Roland N. Ndip and Pascal O. Bessong
    Citation: BMC Infectious Diseases 2016 16:523
    Content type: Research article Published on:

  28. Pertussis is a potentially serious respiratory illness characterized by cough of exceptionally long duration of up to approximately100 days. While macrolide antibiotics are an effective treatment, there is an ...

    Authors: Jennifer K. Knapp, Mark L. Wilson, Susan Murray and Matthew L. Boulton
    Citation: BMC Infectious Diseases 2016 16:522
    Content type: Research article Published on:

  29. Since the launch of the Global Polio Eradication Initiative, all but three countries (Nigeria, Pakistan, and Afghanistan) have apparently interrupted all wild poliovirus (WPV) transmission, and only one of thr...

    Authors: Kevin A. McCarthy, Guillaume Chabot-Couture and Faisal Shuaib
    Citation: BMC Infectious Diseases 2016 16:521
    Content type: Research article Published on:

  30. Botswana is one of eight SADC countries targeting malaria elimination by 2018. Through spirited upscaling of control activities and passive surveillance, significant reductions in case incidence of Plasmodium fal...

    Authors: Thato Motshoge, Grace K. Ababio, Larysa Aleksenko, John Read, Elias Peloewetse, Mazhani Loeto, Tjantilili Mosweunyane, Kentse Moakofhi, Davies S. Ntebele, Simon Chihanga, Mpho Motlaleng, Anderson Chinorumba, Moses Vurayai, Jeffrey M. Pernica, Giacomo M. Paganotti and Isaac K. Quaye
    Citation: BMC Infectious Diseases 2016 16:520
    Content type: Research article Published on:

  31. Authors: Seongman Bae, Taeeun Kim, Min-Chul Kim, Yong Pil Chong, Sung-Han Kim, Heungsup Sung, Young-Suk Lim, Sang-Oh Lee, Mi-Na Kim, Yang Soo Kim, Jun Hee Woo and Sang-Ho Choi
    Citation: BMC Infectious Diseases 2016 16:519
    Content type: Erratum Published on:

    The original article was published in BMC Infectious Diseases 2016 16:252

  32. In a proportion of patients with HIV-associated tuberculosis who develop paradoxical immune reconstitution inflammatory syndrome (IRIS), the clinical course of IRIS is prolonged necessitating substantial healt...

    Authors: Tasnim M. Bana, Maia Lesosky, Dominique J. Pepper, Helen van der Plas, Charlotte Schutz, Rene Goliath, Chelsea Morroni, Marc Mendelson, Gary Maartens, Robert J. Wilkinson and Graeme Meintjes
    Citation: BMC Infectious Diseases 2016 16:518
    Content type: Research article Published on:

  33. Tuberculosis (TB) is a major global health problem and remains the leading cause of morbidity and mortality in developing countries. Routinely used TB diagnostic methods, in most endemic areas, are time-consum...

    Authors: El Mehdi Bentaleb, Mohammed Abid, My Driss El Messaoudi, Brahim Lakssir, El Mostafa Ressami, Saaïd Amzazi, Hassan Sefrioui and Hassan Ait Benhassou
    Citation: BMC Infectious Diseases 2016 16:517
    Content type: Research article Published on:

  34. The spread of multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M. tuberculosis) strains has been a big challenge to the TB control and prevention in China. Knowledge about patterns of drug re...

    Authors: Di Li, Jing-Li Wang, Bin-Ying Ji, Jia-Yi Cui, Xin-Ling Pan, Chang-Long Fan, Chang-Xia Shao, Li-Na Zhao, Yuan-Ping Ma, Liu-Zhuo Zhang, Chun-Lei Zhang, Cai-Bo Dong, Toshio Hattori and Hong Ling
    Citation: BMC Infectious Diseases 2016 16:516
    Content type: Research article Published on:

  35. In the absence of an adult vaccination register, coverage estimates for influenza and pneumococcal vaccination come from surveys and other data sources.

    Authors: Amalie Dyda, Surendra Karki, Andrew Hayen, C. Raina MacIntyre, Robert Menzies, Emily Banks, John M. Kaldor and Bette Liu
    Citation: BMC Infectious Diseases 2016 16:515
    Content type: Research article Published on:

  36. Extrapulmonary tuberculosis (EPTB) is associated with high rates of morbidity and mortality. Diagnosis of EPTB is challenging in resource-limited settings due to difficulties in obtaining samples, as well as t...

    Authors: George Sikalengo, Adria Ramirez, Diana Faini, Kim Mwamelo, Manuel Battegay, Levan Jugheli, Christoph Hatz, Klaus Reither and Emilio Letang
    Citation: BMC Infectious Diseases 2016 16:514
    Content type: Case report Published on:

  37. Congenital CMV (cCMV) infection is a serious public health issue due to both its worldwide prevalence and the severe and permanent impairments it causes. However, awareness of this infection is low in the gene...

    Authors: Sandro Binda, Laura Pellegrinelli, Marco Terraneo, Alessandra Caserini, Valeria Primache, Laura Bubba and Maria Barbi
    Citation: BMC Infectious Diseases 2016 16:513
    Content type: Research article Published on:

  38. Dengue is endemic throughout Cambodia, a country faced with significant health and economic challenges. We undertook a clinical study at the National Paediatric Hospital in Phnom Penh to evaluate clinical diag...

    Authors: Philippe Cavailler, Arnaud Tarantola, Yee Sin Leo, Andrew A. Lover, Anne Rachline, Moniboth Duch, Rekol Huy, Ai Li Quake, Yuvatha Kdan, Veasna Duong, Jeremy L. Brett and Philippe Buchy
    Citation: BMC Infectious Diseases 2016 16:512
    Content type: Research article Published on:

  39. Acute diarrhea is one of the most serious problems in global public health that causes considerable morbidity and mortality worldwide. Human caliciviruses (HuCV) including norovirus (NoV, genogroup GI and GII)...

    Authors: Shun-Xian Zhang, Li Li, Jian-Wen Yin, Miao Jin, Xiang-Yu Kong, Li-Li Pang, Yong-Kang Zhou, Li-Guang Tian, Jia-Xu Chen and Xiao-Nong Zhou
    Citation: BMC Infectious Diseases 2016 16:511
    Content type: Research article Published on:

  40. Among children diagnosed to have chronic rheumatic valvular heart disease (RHD) in Ethiopia, many have been observed to develop recurrence of rheumatic fever (RF) despite secondary prophylaxis. This study dete...

    Authors: Nigus Zegeye, Daniel Asrat, Yimtubezinash Woldeamanuel, Abebe Habte, Etsegenet Gedlu, Tone Tønjum and Abraham Aseffa
    Citation: BMC Infectious Diseases 2016 16:510
    Content type: Research article Published on:

  41. Single nucleotide polymorphism (SNP) genotyping is increasingly being utilized for molecular typing of pathogens and is cost-effective, especially for large numbers of isolates. The goals of this study were 1)...

    Authors: Holly M. Frost, Jennifer L. Anderson, Lynn Ivacic, Brian L. Sloss, John Embil and Jennifer K. Meece
    Citation: BMC Infectious Diseases 2016 16:509
    Content type: Research article Published on:

  42. Diarrhea caused by viruses is a global problem among young children. We investigated two of the most important agents, rotavirus and adenovirus, to provide epidemiological evidence for a better understanding o...

    Authors: Liying Liu, Yuan Qian, You Zhang, Linqing Zhao, Liping Jia and Huijing Dong
    Citation: BMC Infectious Diseases 2016 16:508
    Content type: Research article Published on:

  43. As an immune modulator, vitamin D is involved in various pathophysiological mechanisms in a plethora of diseases. This study aims to correlate the vitamin D deficiency status and clinical progression of liver ...

    Authors: Nghiem Xuan Hoan, Nguyen Khuyen, Mai Thanh Binh, Dao Phuong Giang, Hoang Van Tong, Phan Quoc Hoan, Ngo Tat Trung, Do Tuan Anh, Nguyen Linh Toan, Christian G. Meyer, Peter G. Kremsner, Thirumalaisamy P. Velavan and Le Huu Song
    Citation: BMC Infectious Diseases 2016 16:507
    Content type: Research article Published on:

  44. Despite a worldwide common and progressive nature of benign prostate hyperplasia (BPH) in older men, no association has been observed between a causative pathogen and other etiology so far.

    Authors: Jamshaid Iqbal, Jumanah Al-Rashed and Elijah O. Kehinde
    Citation: BMC Infectious Diseases 2016 16:506
    Content type: Research article Published on:

  45. Although rubella is generally considered a benign childhood disease, infection of a pregnant woman can cause foetal congenital rubella syndrome, which results in embryo-foetal disease and malformations. The sy...

    Authors: Alain Farra, Marilou Pagonendji, Alexandre Manikariza, Dieubéni Rawago, Rock Ouambita-Mabo, Gilbert Guifara and Ionela Gouandjika-Vasilache
    Citation: BMC Infectious Diseases 2016 16:505
    Content type: Research article Published on:

  46. To determine the distribution of Human leukocyte antigen (HLA) class I genotypes in a Ugandan population of persons with tuberculosis (TB) and establish the relationship between class I HLA types and Mycobacteriu...

    Authors: Helen K. Buteme, Rebecca Axelsson-Robertson, Lina Benson, Moses L. Joloba, W. Henry Boom, Gunilla Kallenius and Markus Maeurer
    Citation: BMC Infectious Diseases 2016 16:504
    Content type: Research article Published on:

  47. The use of neuraminidase-inhibiting anti-viral medication to treat influenza is relatively infrequent. Rapid, cost-effective methods for diagnosing influenza are needed to enable appropriate prescribing. Multi...

    Authors: Richard K. Zimmerman, G. K. Balasubramani, Mary Patricia Nowalk, Heather Eng, Leonard Urbanski, Michael L. Jackson, Lisa A. Jackson, Huong Q. McLean, Edward A. Belongia, Arnold S. Monto, Ryan E. Malosh, Manjusha Gaglani, Lydia Clipper, Brendan Flannery and Stephen R. Wisniewski
    Citation: BMC Infectious Diseases 2016 16:503
    Content type: Research article Published on:

  48. Acquisition of genital human papillomavirus (HPV) infection is common among the young, sexually active population. Genital HPV infections do not always lead to seroconversion. We aimed to assess the associatio...

    Authors: Alexandra Kovaleva, Catharina J. Alberts, Tim Waterboer, Angelika Michel, Marieke B. Snijder, Wilma Vermeulen, Liza Coyer, Maria Prins and Maarten Schim van der Loeff
    Citation: BMC Infectious Diseases 2016 16:502
    Content type: Research article Published on:

  49. HIV-associated tuberculosis (TB) co-infection remains an enormous burden to international public health. Post-mortem studies have highlighted the high proportion of HIV-positive adults admitted to hospital wit...

    Authors: Ankur Gupta-Wright, Katherine L. Fielding, Joep J. van Oosterhout, Douglas K. Wilson, Elizabeth L. Corbett, Clare Flach, Krishna P. Reddy, Rochelle P. Walensky, Jurgens A. Peters, Melanie Alufandika-Moyo and Stephen D. Lawn
    Citation: BMC Infectious Diseases 2016 16:501
    Content type: Study protocol Published on:

    The Erratum to this article has been published in BMC Infectious Diseases 2016 16:604

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