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  1. Gonorrhoea is one of the most common sexually transmissible infections in men who have sex with men (MSM). Gonorrhoea rates have increased substantially in recent years. There is concern that increasing gonorr...

    Authors: Eric P. F. Chow, Sandra Walker, Jane S. Hocking, Catriona S. Bradshaw, Marcus Y. Chen, Sepehr N. Tabrizi, Benjamin P. Howden, Matthew G. Law, Kate Maddaford, Tim R. H. Read, David A. Lewis, David M. Whiley, Lei Zhang, Andrew E. Grulich, John M. Kaldor, Vincent J. Cornelisse…
    Citation: BMC Infectious Diseases 2017 17:456
    Content type: Study protocol Published on:

  2. Cystic echinococcosis (CE) is a chronic, complex and neglected zoonotic disease. CE occurs worldwide. In humans, it may result in a wide spectrum of clinical manifestations, ranging from asymptomatic infection...

    Authors: Virginia Velasco-Tirado, Ángela Romero-Alegría, Moncef Belhassen-García, Montserrat Alonso-Sardón, Carmen Esteban-Velasco, Amparo López-Bernús, Adela Carpio-Perez, Marcelo Fernando Jimenez López, Juan Luis Muñoz Bellido, Antonio Muro, Miguel Cordero-Sanchez, Javier Pardo-Lledias and Luis Muñoz-Bellvis
    Citation: BMC Infectious Diseases 2017 17:455
    Content type: Research article Published on:

  3. Plasmodium falciparum infection can progress unpredictably to severe forms including respiratory distress and cerebral malaria. The mechanisms underlying the variable natural course of...

    Authors: Jean Claude Biteghe Bi Essone, Nadine N’Dilimabaka, Julien Ondzaga, Jean Bernard Lekana-Douki, Dieudonné Nkoghe Mba, Philippe Deloron, Dominique Mazier, Frédrérick Gay and Fousseyni S. Touré Ndouo
    Citation: BMC Infectious Diseases 2017 17:454
    Content type: Research article Published on:

  4. Highly active antiretroviral therapy (HAART) has shown a dramatic change in controlling the burden of HIV/AIDS. However, the new challenge of HAART is to allow long-term sustainability. Toxicities, comorbidity...

    Authors: Belay Birlie, Roel Braekers, Tadesse Awoke, Adetayo Kasim and Ziv Shkedy
    Citation: BMC Infectious Diseases 2017 17:453
    Content type: Research Article Published on:

  5. Respiratory syncytial virus (RSV) is responsible for severe respiratory infections and higher costs in medical care. The two aims of this work were to assess the performances of SOFIA®RSV tests in “real-life-labo...

    Authors: Léa C. Tran, Céline Tournus, Julia Dina, Rémy Morello, Jacques Brouard and Astrid Vabret
    Citation: BMC Infectious Diseases 2017 17:452
    Content type: Research article Published on:

  6. Hepatitis E is self-limiting, but can cause death in most at risk groups like pregnant women and those with preexisting acute liver disease. In developing countries it presents as epidemic, in 2014 Hepatitis E...

    Authors: Geofrey Amanya, Samuel Kizito, Immaculate Nabukenya, Joan Kalyango, Collins Atuheire, Hellen Nansumba, Stephen Akena Abwoye, Denis Nixon Opio, Edrisa Kibuuka and Charles Karamagi
    Citation: BMC Infectious Diseases 2017 17:451
    Content type: Research article Published on:

  7. Pyogenic liver abscesses (PLA) remain a significant clinical problem. Unfortunately, little is known about current bacterial susceptibility profiles and the incidence of multidrug resistant organisms (MDROs) c...

    Authors: Marcus M. Mücke, Johanna Kessel, Victoria T. Mücke, Katharina Schwarzkopf, Michael Hogardt, Christoph Stephan, Stefan Zeuzem, Volkhard A. J. Kempf and Christian M. Lange
    Citation: BMC Infectious Diseases 2017 17:450
    Content type: Research article Published on:

  8. Studies focusing on pulmonary tuberculosis in advanced age (≥80 years) are lacking. This study aimed to explore treatment delay, outcomes and their predictors in this group.

    Authors: Chih-Hsin Lee, Jann-Yuan Wang, Hsien-Chun Lin, Pai-Yang Lin, Jer-Hwa Chang, Chi-Won Suk, Li-Na Lee, Chou-Chin Lan and Kuan-Jen Bai
    Citation: BMC Infectious Diseases 2017 17:449
    Content type: Research article Published on:

  9. Cancer predisposes patients to Clostridium difficile infection (CDI) due to health care exposures and medications that disrupt the gut microbiota or reduce immune response. Despite this association, the national ...

    Authors: Andrew Delgado, Ivan A. Reveles, Felicia T. Cabello and Kelly R. Reveles
    Citation: BMC Infectious Diseases 2017 17:448
    Content type: Research article Published on:

  10. The burden of infectious intestinal disease (IID) in the UK is substantial. Negative consequences including sickness absence are common, but little is known about the social patterning of these outcomes, or th...

    Authors: Tanith C. Rose, Natalie L. Adams, Benjamin Barr, Jeremy Hawker, Sarah J. O’Brien, Mara Violato, Margaret Whitehead and David C. Taylor-Robinson
    Citation: BMC Infectious Diseases 2017 17:447
    Content type: Research article Published on:

  11. Authors: Arne Mehl, Bjørn Olav Åsvold, Angela Kümmel, Stian Lydersen, Julie Paulsen, Ingvild Haugan, Erik Solligård, Jan Kristian Damås, Stig Harthug and Tom-Harald Edna
    Citation: BMC Infectious Diseases 2017 17:446
    Content type: Erratum Published on:

    The original article was published in BMC Infectious Diseases 2017 17:116

  12. HIV infection is associated with increased risk of cardiovascular disease beyond that explained by traditional risk factors. Altered gut microbiota, microbial translocation, and immune activation have been pro...

    Authors: Judith M. Haissman, Anna K. Haugaard, Sisse R. Ostrowski, Rolf K. Berge, Johannes R. Hov, Marius Trøseid and Susanne D. Nielsen
    Citation: BMC Infectious Diseases 2017 17:445
    Content type: Research article Published on:

  13. Cervical cancer, nearly all cases of which are caused by one of several high-risk strains of the human papillomavirus (hr-HPV), leads to significant morbidity and mortality in individuals with a cervix. Trans ...

    Authors: Sari L. Reisner, Madeline B. Deutsch, Sarah M. Peitzmeier, Jaclyn M. White Hughto, Timothy Cavanaugh, Dana J. Pardee, Sarah McLean, Elliot J. Marrow, Matthew J. Mimiaga, Lori Panther, Marcy Gelman, Jamison Green and Jennifer Potter
    Citation: BMC Infectious Diseases 2017 17:444
    Content type: Study protocol Published on:

  14. Anaemia is common in malaria. It is important to quantitate the risk of anaemia and to distinguish factors related to the natural history of disease from potential drug toxicity.

    Authors: Julien Zwang, Umberto D’Alessandro, Jean-Louis Ndiaye, Abdoulaye A Djimdé, Grant Dorsey, Andreas A Mårtensson, Corine Karema and Piero L. Olliaro
    Citation: BMC Infectious Diseases 2017 17:443
    Content type: Research article Published on:

  15. We report a case of septic shock syndrome caused by Streptococcus pneumoniae in a patient who had undergone splenectomy due to an autoimmune lymphoproliferative syndrome (ALPS), which is characterized as a dysfun...

    Authors: Josef Singer, Christoph Testori, Peter Schellongowski, Ammon Handisurya, Catharina Müller, Eva-Maria Reitter, Wolfgang Graninger, Paul Knöbl, Thomas Staudinger, Stefan Winkler and Florian Thalhammer
    Citation: BMC Infectious Diseases 2017 17:442
    Content type: Case report Published on:

  16. Acute hepatitis A is a fecal-oral transmitted disease related to inadequate sanitary conditions. In addition to its traditional classification, several outbreaks in the men who have sex with men (MSM) populati...

    Authors: Nan-Yu Chen, Zhuo-Hao Liu, Shian-Sen Shie, Tsung-Hsing Chen and Ting-Shu Wu
    Citation: BMC Infectious Diseases 2017 17:441
    Content type: Research article Published on:

  18. Viral suppression is a critical indicator of HIV treatment success. In the era of test-and-start, little is known about treatment outcomes and time to undetectable viral loads. This study compares treatment ou...

    Authors: Rogers Ssebunya, Rhoda K. Wanyenze, Heather Lukolyo, Milton Mutto, Grace Kisitu, Pauline Amuge, Albert Maganda and Adeodata Kekitiinwa
    Citation: BMC Infectious Diseases 2017 17:439
    Content type: Research article Published on:

  19. Treatment for chronic hepatitis B (CHB) is virtually absent in sub-Saharan Africa. Here we present early experiences from a pilot program for treatment of CHB in Ethiopia.

    Authors: Hanna Aberra, Hailemichael Desalegn, Nega Berhe, Girmay Medhin, Kathrine Stene-Johansen, Svein Gunnar Gundersen and Asgeir Johannessen
    Citation: BMC Infectious Diseases 2017 17:438
    Content type: Research article Published on:

  20. Scaling up HIV testing is the first step in the HIV treatment continuum which is important for controlling the HIV epidemic among men who have sex with men (MSM). Following an online HIV testing intervention a...

    Authors: Ngai Sze Wong, Weiming Tang, Larry Han, John Best, Ye Zhang, Shujie Huang, Heping Zheng, Bin Yang, Chongyi Wei, Stephen W. Pan and Joseph D. Tucker
    Citation: BMC Infectious Diseases 2017 17:437
    Content type: Research article Published on:

  21. Patients with Mycobacterium avium complex (MAC) lung disease (LD) have a heterogeneous prognosis. This study aimed to develop and validate a prognostic scoring model for these patients using independent risk fact...

    Authors: Shogo Kumagai, Akihiro Ito, Toru Hashimoto, Satoshi Marumo, Hironobu Tokumasu, Aya Kotani, Haruka Yamaki, Masahiro Shirata, Koji Furuuchi, Motonari Fukui and Tadashi Ishida
    Citation: BMC Infectious Diseases 2017 17:436
    Content type: Research article Published on:

  22. Shortening the standard 6-month treatment for drug-susceptible pulmonary tuberculosis (DS-PTB) would be a major improvement for TB case management and disease control.

    Authors: Mengqiu Gao, Jingtao Gao, Jian Du, Yuhong Liu, Yao Zhang, Liping Ma, Fengling Mi, Liang Li and Shenjie Tang
    Citation: BMC Infectious Diseases 2017 17:435
    Content type: Study protocol Published on:

  23. The purpose of this study was to identify the clinical characteristics and outcomes of peripheral vascular catheter-related bloodstream infections (PVC-BSIs) and determine the risk of severe complications or d...

    Authors: Akihiro Sato, Itaru Nakamura, Hiroaki Fujita, Ayaka Tsukimori, Takehito Kobayashi, Shinji Fukushima, Takeshi Fujii and Tetsuya Matsumoto
    Citation: BMC Infectious Diseases 2017 17:434
    Content type: Research article Published on:

  24. The Xpert® MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high burden countries to increase case finding among HIV ...

    Authors: Sabine M. Hermans, Juliet A. Babirye, Olive Mbabazi, Francis Kakooza, Robert Colebunders, Barbara Castelnuovo, Christine Sekaggya-Wiltshire, Rosalind Parkes-Ratanshi and Yukari C. Manabe
    Citation: BMC Infectious Diseases 2017 17:433
    Content type: Research article Published on:

  25. The incidence of nontuberculous mycobacteria (NTM) infections is increasing worldwide, however formal evaluations of the epidemiology of NTM infections are limited. Understanding the trends and true prevalence...

    Authors: Hee Jung Yoon, Hwa Young Choi and Moran Ki
    Citation: BMC Infectious Diseases 2017 17:432
    Content type: Research article Published on:

  27. Campylobacter (C.) jejuni is the leading cause of human campylobacteriosis worldwide. We performed a molecular epidemiological study to investigate the genetic relationship among C. je...

    Authors: Sigita Ramonaite, Egle Tamuleviciene, Thomas Alter, Neringa Kasnauskyte and Mindaugas Malakauskas
    Citation: BMC Infectious Diseases 2017 17:430
    Content type: Research article Published on:

  28. Antimicrobial resistance has emerged as a major concern in developing countries. The present study sought to define the pattern of antimicrobial resistance in ICU patients with ventilator-associated pneumonia.

    Authors: Giang M. Tran, Thao P. Ho-Le, Duc T. Ha, Chau H. Tran-Nguyen, Tuyet S. M. Nguyen, Thao T. N. Pham, Tuyet A. Nguyen, Dung A. Nguyen, Hoa Q. Hoang, Ngoc V. Tran and Tuan V. Nguyen
    Citation: BMC Infectious Diseases 2017 17:429
    Content type: Research article Published on:

  29. Dengue results in high morbidity and mortality globally. The knowledge, attitude and practices (KAP) of dengue management, including diagnosis, among primary care physicians (PCPs) are important to reduce deng...

    Authors: Junxiong Pang, Zoe Jane-Lara Hildon, Tun Linn Thein, Jing Jin and Yee Sin Leo
    Citation: BMC Infectious Diseases 2017 17:428
    Content type: Research article Published on:

  30. Genetic variations have been identified in the genome of varicella-zoster virus (VZV) strains using vesicle fluid, varicella scabs and throat swab samples. We report a rare case of VZV-associated uveitis with ...

    Authors: Mayumi Hosogai, Yoko Nakatani, Kensuke Mimura, Shoji Kishi and Hideo Akiyama
    Citation: BMC Infectious Diseases 2017 17:427
    Content type: Case report Published on:

  31. Childhood diarrhea is a major public health problem, especially in developing countries, including Ethiopia. Exploring the spatial pattern of childhood diarrhea is important to monitor and design effective int...

    Authors: Getahun Gebre Bogale, Kassahun Alemu Gelaye, Degefie Tibebe Degefie and Yalemzewod Assefa Gelaw
    Citation: BMC Infectious Diseases 2017 17:426
    Content type: Research article Published on:

  32. Early treatment of acute HIV-1 infection (AHI) is beneficial for patients and could reduce onward transmission. However, guidelines on whom to test for AHI with HIV-1 RNA testing are lacking.

    Authors: Maartje Dijkstra, Godelieve J. de Bree, Ineke G. Stolte, Udi Davidovich, Eduard J. Sanders, Maria Prins and Maarten F. Schim van der Loeff
    Citation: BMC Infectious Diseases 2017 17:425
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2017 17:691

  33. Uremia is likely a risk factor for deep neck infection (DNI). However, only a few relevant cases have been reported, and evidence sufficient to support this hypothesis is lacking. The aim of the study is to in...

    Authors: Geng-He Chang, Ming-Shao Tsai, Chia-Yen Liu, Meng-Hung Lin, Yao-Te Tsai, Cheng-Ming Hsu and Yao-Hsu Yang
    Citation: BMC Infectious Diseases 2017 17:424
    Content type: Database Published on:

  34. Recently there has been a large outbreak of Zika virus infections in Colombia, South America. The epidemic began in September 2015 and continued to April 2017, for the total number of Zika cases reported of 10...

    Authors: Salim Mattar, Carolina Ojeda, Janna Arboleda, German Arrieta, Irene Bosch, Ingrid Botia, Nelson Alvis-Guzman, Carlos Perez-Yepes, Lee Gerhke and German Montero
    Citation: BMC Infectious Diseases 2017 17:423
    Content type: Case report Published on:

  35. Staphylococcus aureus strains are now regarded as zoonotic agents. In pastoral settings where human-animal interaction is intimate, multi-drug resistant microorganisms have become an e...

    Authors: Benon B. Asiimwe, Rossella Baldan, Alberto Trovato and Daniela M. Cirillo
    Citation: BMC Infectious Diseases 2017 17:422
    Content type: Research article Published on:

  36. Residents in long-term care facilities (LTCFs) are vulnerable to tuberculosis (TB) transmission; however, to delineate possible routes of TB transmission in LTCFs is difficult. This study aimed to address the ...

    Authors: Wen-Cheng Chao, Pei-Chun Chuang, Don-Han Wu, Chieh-Liang Wu, Po-Yu Liu, Chi-Chang Shieh and Ruwen Jou
    Citation: BMC Infectious Diseases 2017 17:421
    Content type: Research article Published on:

  37. The aims of this analysis were to investigate treatment completion and adherence among people with ongoing injecting drug use or receiving opioid substitution therapy (OST) in a study of response-guided therap...

    Authors: Evan B. Cunningham, Behzad Hajarizadeh, Olav Dalgard, Janaki Amin, Margaret Hellard, Graham R Foster, Philip Bruggmann, Brian Conway, Markus Backmund, Geert Robaeys, Tracy Swan, Philippa S. Marks, Sophie Quiene, Tanya L Applegate, Martin Weltman, David Shaw…
    Citation: BMC Infectious Diseases 2017 17:420
    Content type: Research article Published on:

  39. Cellulitis is a common infection of the skin and subcutaneous tissues. It is associated with significant morbidity from necrosectomies and amputations especially in sub-Saharan Africa. We aimed at identifying ...

    Authors: Tsi Njim, Leopold Ndemnge Aminde, Valirie Ndip Agbor, Louise Daniele Toukam, Sara Saheb Kashaf and Eric O. Ohuma
    Citation: BMC Infectious Diseases 2017 17:418
    Content type: Research article Published on:

  40. Extensively drug-resistant (XDR) tuberculosis (TB) and multidrug resistant (MDR)-TB with additional resistance to injectable agents or fluoroquinolones are challenging to treat due to lack of available, effect...

    Authors: Aravind Swaminathan, Philipp du Cros, James A. Seddon, Shamsiya Mirgayosieva, Rajabov Asladdin and Zulfiya Dusmatova
    Citation: BMC Infectious Diseases 2017 17:417
    Content type: Case report Published on:

  41. Viral Hepatitis B is of a major public health concern globally, especially in developing countries. Expectant mothers’ knowledge of Mother-To-Child Transmission (MTCT) of the disease is significant in preventi...

    Authors: Frederick Dun-Dery, Martin Nyaaba Adokiya, Williams Walana, Ernestina Yirkyio and Juventus B. Ziem
    Citation: BMC Infectious Diseases 2017 17:416
    Content type: Research article Published on:

  42. This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, on the hazard of time to malaria in a previously studied cohort of children in Ethiopia.

    Authors: Denekew Bitew Belay, Yehenew Getachew Kifle, Ayele Taye Goshu, Jon Michael Gran, Delenasaw Yewhalaw, Luc Duchateau and Arnoldo Frigessi
    Citation: BMC Infectious Diseases 2017 17:415
    Content type: Research Article Published on:

  43. The aim of the study was to assess the applicability of an algorithm predicting 10-year cardiovascular disease (CVD) generated in the setting of the Framingham Heart Study to a real-life, contemporary Italian ...

    Authors: Giuseppe Vittorio De Socio, Giacomo Pucci, Franco Baldelli and Giuseppe Schillaci
    Citation: BMC Infectious Diseases 2017 17:414
    Content type: Research article Published on:

  44. Scrub typhus (ST) is a disease caused by an obligate intracellular bacterium, Orientia tsutsugamushi, an organism that requires a BSL3 laboratory for propagation. The disease is hallmarked by an eschar at the sit...

    Authors: Chien-Chung Chao, Zhiwen Zhang, Tatyana Belinskaya, Wilawan Thipmontree, Wiwit Tantibhedyangkul, Saowaluk Silpasakorn, Ekkarat Wongsawat, Yupin Suputtamongkol and Wei-Mei Ching
    Citation: BMC Infectious Diseases 2017 17:413
    Content type: Research article Published on:

  45. A previous genome-wide association study identified 2 susceptibility loci for severe dengue at MICB rs3132468 and PLCE1 rs3740360 and further work showed these mutations to be also associated with less severe cli...

    Authors: James Whitehorn, Duong Thi Hue Kien, Nguyen Than Ha Quyen, Bridget Wills, Nguyen Van Vinh Chau, Dong Thi Hoai Tam, Nguyen Minh Tuan, Thomas Jaenisch, Martin Hibberd, Chiea Chuen Khor and Cameron P. Simmons
    Citation: BMC Infectious Diseases 2017 17:412
    Content type: Research article Published on:

  46. Seasonal variations are often observed for respiratory tract infections; however, limited information is available regarding seasonal patterns of acquisition of common cystic fibrosis (CF)-related respiratory ...

    Authors: Kevin J. Psoter, Anneclaire J. De Roos, Jon Wakefield, Jonathan D. Mayer and Margaret Rosenfeld
    Citation: BMC Infectious Diseases 2017 17:411
    Content type: Research article Published on:

  47. Due to the populations’ susceptibility, DENV-4 introduction in 2010 led to the occurrence of explosive epidemics in the following years in Brazil. In 2011, DENV-4 was identified in Rio de Janeiro (RJ) and it w...

    Authors: Manoela Heringer, Thiara Manuele A Souza, Monique da Rocha Q Lima, Priscila Conrado G Nunes, Nieli Rodrigues da C Faria, Fernanda de Bruycker-Nogueira, Thaís Chouin-Carneiro, Rita Maria R Nogueira and Flavia Barreto dos Santos
    Citation: BMC Infectious Diseases 2017 17:410
    Content type: Research article Published on:

  48. In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods. Serology data suggest that infections wit...

    Authors: Mohammadreza Sadeghi, Yilin Wang, Torbjörn Ramqvist, Leena-Maija Aaltonen, Lari Pyöriä, Mari Toppinen, Maria Söderlund-Venermo and Klaus Hedman
    Citation: BMC Infectious Diseases 2017 17:409
    Content type: Research article Published on:

  49. Healthcare workers in high tuberculosis burdened countries are occupationally exposed to the tuberculosis disease with uncomplicated and complicated tuberculosis on the increase among them. Most of them acquire M...

    Authors: Celso Belo and Saloshni Naidoo
    Citation: BMC Infectious Diseases 2017 17:408
    Content type: Research article Published on:

  50. Pulmonary nocardiosis mimic pulmonary tuberculosis in most clinical and radiological manifestations. In Tanzania, where tuberculosis is one of the major public health threat clinical impact of nocardiosis as t...

    Authors: Abubakar S. Hoza, Sayoki G.S. Mfinanga, Irmgard Moser and Brigitte König
    Citation: BMC Infectious Diseases 2017 17:407
    Content type: Research article Published on:

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