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Table 2 Clinical, parasitological and other characteristics of patients in different major temporal patterns

From: Temporal changes in haematocrit following artemisinin-based combination treatments of uncomplicated falciparum malaria in children

  aPattern 1 bPattern 2 cPattern 6 ALL eP value
Number (%) 123 (49.6) 48 (19.4) 57 (23) 228 (92)  
Gender
 M/F 66/57 21/27 33/24 120/108 0.33
Age (year)
 Mean (sd) 7.3 (3.6) 5.6 (2.7) 5.3 (2.7) 6.5 (3.3) < 0.0001
 Range 0.7–14 2–10 1.2–12.5 0.7–14  
Duration of illness (days)
 Mean (sd) 2.5 (1.1) 2.8 (1) 3.2 (1.3) 2.7 (1.2) < 0.0001
 Range 1–7 1–5 1–7 1–7  
Weight (kg)
 Mean (sd) 20.2 (7.5) 16.7 (5.3) 16.0 (4.3) 18.4 (6.7) 0.009
 Range 7–40 9–31 7–26 7–40  
Haematocrit (%)
 Mean (sd) 34.7 (2.7) 32.4 (2.8) 26.4 (2.6) 32.3 (4.4) < 0.0001
 Range 30–42 30–38 18–29 18–42  
Temperature (°C)
 Mean (sd) 38.4 (1.1) 38.6 (1) 38.4 (1.2) 38.4 (1.1) 0.60
 Range 35–40.9 35–40.1 35.9–40.5 35–40.9  
No. with temp.
 i. >37.4 °C (%) 97 (79) 42 (88) 43 (75) 182 (80) 0.28
 ii. >40.0 °C (%) 8 (7) 1 (2) 14 (25) 23 (10) < 0.0001
Parasitaemia (μL−1)
 Geometric Mean 52,037 59,361 64,514 56,468 0.37
 Range 2,000-459,000 8,000-1,080,200 2,094-346,153 2,000-1,080,200  
No. with ≥100,000 μL−1(%) 34 (27.6) 11 (22.9) 18 (31.6) 63 (27.6) d0.61
  1. aHaematocrit ≥ 30 % before and following treatment
  2. bHaematocrit ≥ 30 % before treatment, two consecutive haematocrit < 30 % within 14 days of treatment, followed by a rise to ≥ 30 % [Early monophasic fall]
  3. cHaematocrit < 30 % before treatment, followed by a rise to ≥ 30 % after treatment [malaria-associated anaemia at presentation and recovery from anaemia]
  4. dChi-square test
  5. eP values quoted are for comparison across all three groups