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  1. Hand, foot and mouth disease (HFMD) is one of the highest reported infectious diseases with several outbreaks across the world. This study aimed at describing epidemiological characteristics, investigating spa...

    Authors: Xinrui Wu, Shixiong Hu, Abuaku Benjamin Kwaku, Qi Li, Kaiwei Luo, Ying Zhou and Hongzhuan Tan
    Citation: BMC Infectious Diseases 2017 17:645
    Content type: Research article Published on:

  2. Bordetella bronchiseptica (B.bronchiseptica) is a frequent cause of respiratory infections in animals but rarely causes serious infection in humans. We present a rare case of B. bronch...

    Authors: Manlio Monti, Danila Diano, Francesco Allegrini, Angelo Delmonte, Valentina Fausti, Paola Cravero, Giulia Marcantognini and Giovanni Luca Frassineti
    Citation: BMC Infectious Diseases 2017 17:644
    Content type: Case report Published on:

  3. The epidemiology of ICU pneumonia caused by Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) is not fully described, but is urgently needed to support the development of effective inte...

    Authors: Fleur P. Paling, Darren P. R. Troeman, Martin Wolkewitz, Rubana Kalyani, Daniël R. Prins, Susanne Weber, Christine Lammens, Leen Timbermont, Herman Goossens, Surbhi Malhotra-Kumar, Frangiscos Sifakis, Marc J. M. Bonten and Jan A. J. W. Kluytmans
    Citation: BMC Infectious Diseases 2017 17:643
    Content type: Study protocol Published on:

  4. A global pandemic mortality study found prominent regional mortality variations in 2009 for Influenza A(H1N1)pdm09. Our study attempts to identify factors that explain why the pandemic mortality burden was hig...

    Authors: Kathleen F. Morales, John Paget and Peter Spreeuwenberg
    Citation: BMC Infectious Diseases 2017 17:642
    Content type: Research article Published on:

  5. Since the recent introduction of GeneXepert for the detection of Tuberculosis (TB) drug resistance mutations in both primary resistance and acquired resistance in Zambia, little has been documented in literatu...

    Authors: Sepiso K. Masenga, Harrison Mubila and Benson M. Hamooya
    Citation: BMC Infectious Diseases 2017 17:640
    Content type: Research article Published on:

  6. Due to outdoor and residual transmission and insecticide resistance, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) will be insufficient as stand-alone malaria vector control interve...

    Authors: Robert S. McCann, Henk van den Berg, Peter J. Diggle, Michèle van Vugt, Dianne J. Terlouw, Kamija S. Phiri, Aurelio Di Pasquale, Nicolas Maire, Steven Gowelo, Monicah M. Mburu, Alinune N. Kabaghe, Themba Mzilahowa, Michael G. Chipeta and Willem Takken
    Citation: BMC Infectious Diseases 2017 17:639
    Content type: Study protocol Published on:

  7. Stenotrophomonas maltophilia (S. maltophilia) bacteremia causes significant morbidity and mortality in immunocompromised hosts. However, incidence and risk factors for mortality in S. ...

    Authors: Kaito Harada, Noritaka Sekiya, Tatsuya Konishi, Akihito Nagata, Yuta Yamada, Toshiaki Takezaki, Satoshi Kaito, Shuhei Kurosawa, Masahiro Sakaguchi, Shunichiro Yasuda, Shugo Sasaki, Kosuke Yoshioka, Kyoko Watakabe-Inamoto, Aiko Igarashi, Yuho Najima, Takeshi Hagino…
    Citation: BMC Infectious Diseases 2017 17:638
    Content type: Research article Published on:

  8. The purpose of this study was to determine the shifting trends in bacteriology and antimicrobial resistance of infectious specimens isolated from gastrointestinal (GI) fistula patients over eight years in China.

    Authors: Qinjie Liu, Jianan Ren, Xiuwen Wu, Gefei Wang, Zhiwei Wang, Jie Wu, Jinjian Huang, Tianyu Lu and Jieshou Li
    Citation: BMC Infectious Diseases 2017 17:637
    Content type: Research article Published on:

  9. Radiotherapy may represent an alternative treatment modality for cystic echinococcosis (CE), but there is no adequate evidence for it up to now. In this study, we aim to investigate the parasiticidal effects o...

    Authors: Rui Mao, Ge Wu, Hui Wang, Pengfei Lu, Jun Li, Haitao Li, Aimudula Ainiwaer, Yiwei Bai, Mingyang Shu, Yongxing Bao and Wenbao Zhang
    Citation: BMC Infectious Diseases 2017 17:636
    Content type: Research article Published on:

  10. Current knowledge of the epidemiology of Clostridium difficile infection in Asia, and in particular the Greater Mekong Subregion, is very limited. Only a few studies from Thailand and Vietnam have been reported f...

    Authors: Elaine Cheong, Tamalee Roberts, Sayaphet Rattanavong, Thomas V. Riley, Paul N. Newton and David A. B. Dance
    Citation: BMC Infectious Diseases 2017 17:635
    Content type: Research article Published on:

  11. Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on c...

    Authors: Patricia Therese Campbell, Jodie McVernon, Niraj Shrestha, Paula M. Nathan and Nicholas Geard
    Citation: BMC Infectious Diseases 2017 17:634
    Content type: Research article Published on:

  12. Hemophagocytic lymphohistiocytosis (HLH) is an uncommon systemic inflammatory condition that can result from infections, autoimmune diseases and malignancies. It is a rarely reported life threatening complicat...

    Authors: Farheen Manji, Evan Wilson, Etienne Mahe, John Gill and John Conly
    Citation: BMC Infectious Diseases 2017 17:633
    Content type: Case report Published on:

  13. Protective antibody immunity against the influenza A virus wanes in 2–7 years due to antigenic drift of the virus’ surface proteins. The duration of immune protection is highly variable because antigenic evolu...

    Authors: Rutger G. Woolthuis, Jacco Wallinga and Michiel van Boven
    Citation: BMC Infectious Diseases 2017 17:632
    Content type: Research article Published on:

  14. Infectious disease is the leading cause of death worldwide, and diagnosis of polymicrobial and fungal infections is increasingly challenging in the clinical setting. Conventionally, molecular detection is stil...

    Authors: Lalanika M. Abayasekara, Jennifer Perera, Vishvanath Chandrasekharan, Vaz S. Gnanam, Nisala A. Udunuwara, Dileepa S. Liyanage, Nuwani E. Bulathsinhala, Subhashanie Adikary, Janith V. S. Aluthmuhandiram, Chrishanthi S. Thanaseelan, D. Portia Tharmakulasingam, Tharaga Karunakaran and Janahan Ilango
    Citation: BMC Infectious Diseases 2017 17:631
    Content type: Technical advance Published on:

  16. Local understandings of malaria and use of preventive measures-are critical factors in sustained control of malaria. This study assessed caretakers’ knowledge on malaria, use of Long Lasting Insecticide Treate...

    Authors: Zewdie Birhanu, Yemane Ye-ebiyo Yihdego and Delenasaw Yewhalaw
    Citation: BMC Infectious Diseases 2017 17:629
    Content type: Research article Published on:

  17. Leptospirosis is a re-emerging zoonotic disease caused by pathogenic strains of bacteria belonging to genus Leptospira whose symptoms can range from mild clinical manifestations to a severe life threatening illne...

    Authors: Lalmani Regmi, Kishor Pandey, Meena Malla, Santosh Khanal and Basu Dev Pandey
    Citation: BMC Infectious Diseases 2017 17:628
    Content type: Research article Published on:

  18. Human strongyloidiasis is a chronic and persistent gastrointestinal disease caused by infection with soil-transmitted helminths of the genus Strongyloides. The aim of this research was to obtain diagnostic preval...

    Authors: Thidarat K. Prasongdee, Pokkamol Laoraksawong, Wanida Kanarkard, Ratthaphol Kraiklang, Kraisit Sathapornworachai, Sureeporn Naonongwai, Porntip Laummaunwai, Oranuch Sanpool, Pewpan M. Intapan and Wanchai Maleewong
    Citation: BMC Infectious Diseases 2017 17:627
    Content type: Research article Published on:

  19. Maternal syphilis is a health threat to both the pregnant women and the children. This study aimed to delineate the longitudinal trend of maternal syphilis and burden of associated adverse pregnant outcomes (A...

    Authors: Yang Li, Liping Zhu, Li Du, Lingxiao Qu, Weili Jiang and Biao Xu
    Citation: BMC Infectious Diseases 2017 17:626
    Content type: Research article Published on:

  20. Varicella or chickenpox was not a notifiable disease until 2005 in Sri Lanka and only a few studies have been conducted on the epidemiology of VZV infection in the country. The anti­VZV IgG sero-prevalence amo...

    Authors: Saluwadana Walawwe Pavithra Lakmini Daulagala, Faseeha Noordeen, Mohamed Mukthar Fathina Fara, Chathura Rathnayake and Kapila Gunawardana
    Citation: BMC Infectious Diseases 2017 17:625
    Content type: Research article Published on:

  21. Hepatitis C (HCV) infection causes an asymptomatic chronic hepatitis in most affected individuals, which often remains undetected until cirrhosis and cirrhosis-related complications occur. Screening of high-ri...

    Authors: H. Kileng, L. Bernfort, T. Gutteberg, O.S. Moen, M.G. Kristiansen, E.J. Paulssen, L.K. Berg, J. Florholmen and R. Goll
    Citation: BMC Infectious Diseases 2017 17:624
    Content type: Research article Published on:

  22. Sub-Saharan Africa continues to document high pediatric tuberculosis (TB) burden, especially among the urban poor. One recommended preventive strategy involves tracking and isoniazid preventive therapy (IPT) f...

    Authors: Florence Nafula Okwara, John Paul Oyore, Fred Nabwire Were and Samson Gwer
    Citation: BMC Infectious Diseases 2017 17:623
    Content type: Research article Published on:

  23. Dolutegravir (DTG) is metabolized mainly by uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1), and partly by cytochrome P450 3A (CYP3A). Therefore, we focused on UGT1A1 gene polymorphisms (*6 and *28...

    Authors: Hiroki Yagura, Dai Watanabe, Hiroyuki Kushida, Kosuke Tomishima, Hiroaki Togami, Atsushi Hirano, Masaaki Takahashi, Kazuyuki Hirota, Motoko Ikuma, Daisuke Kasai, Yasuharu Nishida, Munehiro Yoshino, Kunio Yamazaki, Tomoko Uehira and Takuma Shirasaka
    Citation: BMC Infectious Diseases 2017 17:622
    Content type: Research article Published on:

  24. A simple and accurate molecular diagnostic method for malaria is urgently needed due to the limitations of conventional microscopic examination. In this study, we demonstrate a new diagnostic procedure for hum...

    Authors: Kazuo Imai, Norihito Tarumoto, Kazuhisa Misawa, Lucky Ronald Runtuwene, Jun Sakai, Kyoko Hayashida, Yuki Eshita, Ryuichiro Maeda, Josef Tuda, Takashi Murakami, Shigefumi Maesaki, Yutaka Suzuki, Junya Yamagishi and Takuya Maeda
    Citation: BMC Infectious Diseases 2017 17:621
    Content type: Research article Published on:

  25. The treatment failure and reinfection rates among syphilis patients are high, and relevant studies in China are limited. The aim of this study was to detect the rates of treatment failure and reinfection after...

    Authors: Zhenzhou Luo, Lin Zhu, Yi Ding, Jun Yuan, Wu Li, Qiuhong Wu, Lishan Tian, Li Zhang, Guomao Zhou, Tao Zhang, Jianping Ma, Zhongwei Chen, Tubao Yang, Tiejian Feng and Min Zhang
    Citation: BMC Infectious Diseases 2017 17:620
    Content type: Research article Published on:

  26. The clinical care of people living with HIV changed fundamentally as a result of the development of effective antiretroviral therapy (ART). HIV infection is now a long-term treatable condition. We report a nat...

    Authors: A. Molloy, H. Curtis, F. Burns and A. Freedman
    Citation: BMC Infectious Diseases 2017 17:619
    Content type: Research article Published on:

  27. Hepatitis B virus (HBV) affects people worldwide but the local burden especially in pregnant women and their new born babies is unknown. In Rwanda HIV-infected individuals who are also infected with HBV are su...

    Authors: Mwumvaneza Mutagoma, Helene Balisanga, Samuel S. Malamba, Dieudonné Sebuhoro, Eric Remera, David J. Riedel, Steve Kanters and Sabin Nsanzimana
    Citation: BMC Infectious Diseases 2017 17:618
    Content type: Research article Published on:

  28. Surveillance of Neisseria gonorrhoeae antimicrobial susceptibility in Europe is performed through the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP), which additionally provides data to info...

    Authors: Michelle J. Cole, Gianfranco Spiteri, Susanne Jacobsson, Neil Woodford, Francesco Tripodo, Andrew J. Amato-Gauci and Magnus Unemo
    Citation: BMC Infectious Diseases 2017 17:617
    Content type: Research article Published on:

  29. Antimicrobial resistance (AMR) is widely acknowledged as a global problem, yet in many parts of the world its magnitude is still not well understood. This review, using a public health focused approach, aimed ...

    Authors: Birkneh Tilahun Tadesse, Elizabeth A. Ashley, Stefano Ongarello, Joshua Havumaki, Miranga Wijegoonewardena, Iveth J. González and Sabine Dittrich
    Citation: BMC Infectious Diseases 2017 17:616
    Content type: Research article Published on:

  31. Bacterial pathogens are a major cause of childhood community acquired lower respiratory tract infections (CA-LRTIs), and few data described the impact of antimicrobial resistance on children with CA-LRTIs. Thi...

    Authors: Xiaoguang He, Mingyu Xie, Siping Li, Junqin Ye, Qi Peng, Qiang Ma, Xiaomei Lu and Baimao Zhong
    Citation: BMC Infectious Diseases 2017 17:614
    Content type: Research article Published on:

  32. The relatively simple and cheaper light-emitting diode fluorescent microscopy (LED-FM) was recommended by the World Health Organization (WHO) to replace the conventional tuberculosis (TB) microscopy in both hi...

    Authors: Alemu Gadissa Gelalcha, Abebaw Kebede and Hassen Mamo
    Citation: BMC Infectious Diseases 2017 17:613
    Content type: Research article Published on:

  33. Individual-based models (IBMs) are useful to simulate events subject to stochasticity and/or heterogeneity, and have become well established to model the potential (re)emergence of pathogens (e.g., pandemic in...

    Authors: Lander Willem, Frederik Verelst, Joke Bilcke, Niel Hens and Philippe Beutels
    Citation: BMC Infectious Diseases 2017 17:612
    Content type: Research Article Published on:

  34. With potent antiretroviral drugs, HIV infection is becoming a chronic disease. Emergence of comorbidities, particularly cardiovascular disease (CVD) has become a leading concern for patients living with the in...

    Authors: Madeleine Durand, Carl Chartrand-Lefebvre, Jean-Guy Baril, Sylvie Trottier, Benoit Trottier, Marianne Harris, Sharon Walmsley, Brian Conway, Alexander Wong, Jean-Pierre Routy, Colin Kovacs, Paul A. MacPherson, Kenneth Marc Monteith, Samer Mansour, George Thanassoulis, Michal Abrahamowicz…
    Citation: BMC Infectious Diseases 2017 17:611
    Content type: Study protocol Published on:

  35. Concurrent diabetes mellitus and tuberculosis represent a significant health problem worldwide. Patients with diabetes mellitus have a high risk of tuberculosis, which may be mediated by an abnormal innate imm...

    Authors: María Teresa Herrera, Yolanda Gonzalez, Fernando Hernández-Sánchez, Guadalupe Fabián-San Miguel and Martha Torres
    Citation: BMC Infectious Diseases 2017 17:610
    Content type: Research article Published on:

  36. Clinical syndromes associated with West Nile virus (WNV) infection range from fever to neuroinvasive disease. Understanding WNV epidemiology and disease history is important for guiding patient care and health...

    Authors: Man Wah Yeung, Emily Shing, Mark Nelder and Beate Sander
    Citation: BMC Infectious Diseases 2017 17:609
    Content type: Research article Published on:

  37. Kerstersia gyiorum is an extremely rare pathogen of human infection. It can cause chronic infection in patients with underlying conditions. It can easily be misdiagnosed if proper diag...

    Authors: Irmak Baran, Arife Polat Düzgün, İpek Mumcuoğlu and Neriman Aksu
    Citation: BMC Infectious Diseases 2017 17:608
    Content type: Case report Published on:

  38. Device-associated health care-associated infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit. The aim of this study was to assess the incidence of DA-HAIs, mortality an...

    Authors: Stelios Iordanou, Nicos Middleton, Elizabeth Papathanassoglou and Vasilios Raftopoulos
    Citation: BMC Infectious Diseases 2017 17:607
    Content type: Research article Published on:

  39. Little is known regarding the restoration of the specific immune response after combined antiretroviral therapy (cART) and anti-tuberculosis (TB) therapy introduction among TB-HIV patients. In this study, we e...

    Authors: Tatiana Pereira da Silva, Carmem Beatriz Wagner Giacoia-Gripp, Carolina A. Schmaltz, Flavia Marinho Sant’Anna, Maria Helena Saad, Juliana Arruda de Matos, Julio Castro Alves de Lima e Silva, Valeria Cavalcanti Rolla and Mariza Gonçalves Morgado
    Citation: BMC Infectious Diseases 2017 17:606
    Content type: Research article Published on:

  40. We describe the accumulation of HIV-1 drug resistance and its effect on the activity of next-line components in patients with virological failure (HIV-1 RNA >1000 copies/mL) after 1 year (t1) of first-line ant...

    Authors: Andrea De Luca, Zita Jorge Sidumo, Giacomo Zanelli, Noorjehan Abdul Magid, Richard Luhanga, Davide Brambilla, Giuseppe Liotta, Sandro Mancinelli, Maria Cristina Marazzi, Leonardo Palombi and Susanna Ceffa
    Citation: BMC Infectious Diseases 2017 17:605
    Content type: Research article Published on:

  41. Every year, over 1 million people develop isoniazid (INH) resistant tuberculosis (TB). Yet, the optimal treatment regimen remains unclear. Given increasing prevalence, the clinical efficacy of regimens used by...

    Authors: Kamila Romanowski, Leslie Y. Chiang, David Z. Roth, Mel Krajden, Patrick Tang, Victoria J. Cook and James C. Johnston
    Citation: BMC Infectious Diseases 2017 17:604
    Content type: Research article Published on:

  42. The majority of antibiotics consumed in developed countries are prescribed in primary care. However, little is known about resistance levels in the primary care population.

    Authors: Mia Tyrstrup, Eva Melander, Katarina Hedin, Anders Beckman and Sigvard Mölstad
    Citation: BMC Infectious Diseases 2017 17:603
    Content type: Research article Published on:

  43. Despite the guidelines for managing sexual assault being in place, victims of sexual assault attended to at Kadoma General Hospital consistently raised complaints related to the quality of care offered. Medico...

    Authors: Stanley Tapesana, Daniel Chirundu, Gerald Shambira, Notion Tafara Gombe, Tsitsi Patience Juru and Tshimanga Mufuta
    Citation: BMC Infectious Diseases 2017 17:602
    Content type: Research article Published on:

  44. Hepatitis B virus (HBV) infection is a major public health problem globally. HBV genotypes and subgenotypes influence disease transmission, progression, and treatment outcome. A study was conducted among treat...

    Authors: Thi Ton Taht Bui, Tan Thanh Tran, My Ngoc Nghiem, Pierre Rahman, Thi Thanh Thanh Tran, Man Nguyen Huy Dinh, Manh Hung Le, Van Vinh Chau Nguyen, Guy Thwaites and Motiur Rahman
    Citation: BMC Infectious Diseases 2017 17:601
    Content type: Research article Published on:

  45. In the search for fast, simple and better ways for diagnosis of tuberculosis (TB), there is need to discover and evaluate new biomarkers that are found in samples other than sputum to determine their effective...

    Authors: Anna Ritah Namuganga, Novel N. Chegou, Paul Mubiri, Gerhard Walzl and Harriet Mayanja-Kizza
    Citation: BMC Infectious Diseases 2017 17:600
    Content type: Research article Published on:

  46. Rabies is a global fatal infectious viral disease that is characterized by a high mortality after onset of clinical symptoms. Recently, there has been an increase in the incidence of rabies in China. The aim o...

    Authors: Jian-Ming Zhang, Zhi-Shan Zhang, Yan-Qin Deng, Shou-Li Wu, Wei Wang and Yan-Sheng Yan
    Citation: BMC Infectious Diseases 2017 17:599
    Content type: Research article Published on:

  47. Information is limited about the effect of restricted carbapenem use on clearance of multi-drug resistant Acinetobacter baumannii (MDRAB). We sought to determine the time effect of antibiotic exposure on multi-dr...

    Authors: Po-Yen Huang, Shian-Sen Shie, Jung-Jr Ye, Shih-Pin Lin, Tsui-Ping Liu, Ting-Shu Wu, Tsu-Lan Wu, Shiow-Shuh Chuang, Ming-Huei Cheng, Yu-Chia Hsieh and Ching-Tai Huang
    Citation: BMC Infectious Diseases 2017 17:598
    Content type: Research article Published on:

  48. During the 2013–2016 West Africa Ebola virus disease (EVD) epidemic, some EVD patients, mostly health care workers, were evacuated to Europe and the USA.

    Authors: Emanuele Nicastri, Antonio Brucato, Nicola Petrosillo, Gianluigi Biava, Timothy M. Uyeki and Giuseppe Ippolito
    Citation: BMC Infectious Diseases 2017 17:597
    Content type: Case report Published on:

  49. A marked increase in the incidence rate of scarlet fever imposed a considerable burden on the health of children aged 5 to 15 years. The main purpose of this study was to depict the spatiotemporal epidemiologi...

    Authors: Qi Zhang, Wendong Liu, Wang Ma, Yingying Shi, Ying Wu, Yuan Li, Shuyi Liang, Yefei Zhu and Minghao Zhou
    Citation: BMC Infectious Diseases 2017 17:596
    Content type: Research article Published on:

  50. Rapid immunochromatographic tests (ICT) for dengue non-structural protein 1 (NS1) have shown good performance for diagnosing acute-phase dengue in serum in laboratory settings, but rarely have been assessed in...

    Authors: Verónica Elizabeth Mata, Sonia Regina Lambert Passos, Yara Hahr Marques Hökerberg, Guilherme Miguéis Berardinelli, Maria Angelica Borges dos Santos, Levy Vilas Boas Fukuoka, Anna Carolina Fontoura Seixas Rangel Maciel, Cintia Damasceno dos Santos Rodrigues, Aline da Silva Santos and Raquel de Vasconcellos Carvalhaes de Oliveira
    Citation: BMC Infectious Diseases 2017 17:594
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2017 17:710

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