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  1. Hepatitis E virus (HEV) has emerged as an important cause of epidemic and sporadic acute viral hepatitis worldwide. This study investigated the seroprevalence of anti-HEV in a Korean population and compared th...

    Authors: Hyun Kyung Park, Sook-Hyang Jeong, Jin-Wook Kim, Byung-Hyun Woo, Dong Ho Lee, Hyun Young Kim and Soyeon Ahn
    Citation: BMC Infectious Diseases 2012 12:142
    Content type: Research article Published on:

  2. This study was aimed to investigate the diagnostic value of fiberoptic bronchoscopy (FOB) with chest high-resolution computed tomography (HRCT) for the rapid diagnosis of active pulmonary tuberculosis (PTB) in...

    Authors: Jung Ar Shin, Yoon Soo Chang, Tae Hoon Kim, Hyung Jung Kim, Chul Min Ahn and Min Kwang Byun
    Citation: BMC Infectious Diseases 2012 12:141
    Content type: Research article Published on:

  3. In the Netherlands, infection with varicella-zoster virus (VZV) is considered a benign common childhood illness and routine vaccination against VZV is not done. In 1995 it was estimated that 98-100% of the adu...

    Authors: Gini GC van Rijckevorsel, Marjolein Damen, Gerard J Sonder, Maarten F Schim van der Loeff and Anneke van den Hoek
    Citation: BMC Infectious Diseases 2012 12:140
    Content type: Research article Published on:

  4. Asplenic individuals are susceptible for overwhelming infection with Streptococcus pneumoniae, carrying a high mortality. Although Toll-like receptor (TLR)-2 is considered the major receptor for Gram-positive bac...

    Authors: Adriana J J Lammers, Alexander P N A de Porto, Onno J de Boer, Sandrine Florquin and Tom van der Poll
    Citation: BMC Infectious Diseases 2012 12:139
    Content type: Research article Published on:

  5. Pertussis is a reported vaccine-preventable respiratory disease in China. Because the routine laboratory methods for diagnosis are not in use, the reported cases are mainly in infants with classical paroxysmal...

    Authors: Qi Zhang, Huizhen Zheng, Meizhen Liu, Ke Han, Jun Shu, Chenggang Wu, Ning Xu, Qiushui He and Huiming Luo
    Citation: BMC Infectious Diseases 2012 12:138
    Content type: Research article Published on:

  6. Human papillomavirus (HPV) seroprevalence data have not previously been reported for different geographical regions of China. This study investigated the cross-sectional seroprevalence of antibodies to HPV 6, ...

    Authors: Jia Ji, Hai-Kui Sun, Jennifer S Smith, He Wang, Mark T Esser, Shangying Hu, Robert G Pretorius, Wen Chen, Jerome L Belinson and You-Lin Qiao
    Citation: BMC Infectious Diseases 2012 12:137
    Content type: Research article Published on:

  7. The epidemic of encephalitis lethargica (EL), called classical EL, was rampant throughout the world during 1917–1926, affecting half a million persons. The acute phase was lethal for many victims. Post-encepha...

    Authors: Robert R Dourmashkin, Glynis Dunn, Victor Castano and Sherman A McCall
    Citation: BMC Infectious Diseases 2012 12:136
    Content type: Research article Published on:

  8. The vast majority of research in the area of community-acquired pneumonia (CAP) has been based on patients admitted to hospital. And yet, the majority of patients with CAP are treated on an ambulatory basis as...

    Authors: Dean T Eurich, Sumit R Majumdar and Thomas J Marrie
    Citation: BMC Infectious Diseases 2012 12:135
    Content type: Research article Published on:

  9. The etiologic profile of community-acquired pneumonia (CAP) for each age group could be similar among inpatients and outpatients. This fact brings up the link between etiology of CAP and its clinical evolution...

    Authors: Alberto Capelastegui, Pedro P España, Amaia Bilbao, Julio Gamazo, Federico Medel, Juan Salgado, Iñaki Gorostiaga, Maria Jose Lopez de Goicoechea, Inmaculada Gorordo, Cristobal Esteban, Lander Altube and Jose M Quintana
    Citation: BMC Infectious Diseases 2012 12:134
    Content type: Research article Published on:

  10. Daptomycin is a rapidly bactericidal agent with broad coverage against Gram-positive organisms, including Staphylococcus aureus, the most frequent cause of osteomyelitis. The objective of this study was to descri...

    Authors: Jason C Gallagher, Jennifer A Huntington, Darren Culshaw, Scott A McConnell, Minjung Yoon and Elie Berbari
    Citation: BMC Infectious Diseases 2012 12:133
    Content type: Research article Published on:

  11. Dengue fever has been a major public health concern in China since it re-emerged in Guangdong province in 1978. This study aimed to explore spatiotemporal characteristics of dengue fever cases for both indigen...

    Authors: Zhongjie Li, Wenwu Yin, Archie Clements, Gail Williams, Shengjie Lai, Hang Zhou, Dan Zhao, Yansha Guo, Yonghui Zhang, Jinfeng Wang, Wenbiao Hu and Weizhong Yang
    Citation: BMC Infectious Diseases 2012 12:132
    Content type: Research article Published on:

  12. HBeAg presence in childbearing-age women is a major determinant of perinatal hepatitis B virus (HBV) transmission. The risk of developing chronic HBV infection and liver disease is highest at young age. Our ai...

    Authors: Jördis J Ott, Gretchen A Stevens and Steven T Wiersma
    Citation: BMC Infectious Diseases 2012 12:131
    Content type: Research article Published on:

  13. Methadone maintenance treatment (MMT) was implemented in China since 2004. It was initiated in 8 pilot clinics and subsequently expanded to 738 clinics by the end of 2011. Numerous individual research studies ...

    Authors: Xun Zhuang, Yanxian Liang, Eric PF Chow, Yafei Wang, David P Wilson and Lei Zhang
    Citation: BMC Infectious Diseases 2012 12:130
    Content type: Research article Published on:

  14. Rapid influenza diagnosis is important for early identification of outbreaks, effective management of high-risk contacts, appropriate antiviral use, decreased inappropriate antibiotic use and avoidance of unne...

    Authors: Tabitha Woolpert, Stephanie Brodine, Hector Lemus, Jill Waalen, Patrick Blair and Dennis Faix
    Citation: BMC Infectious Diseases 2012 12:129
    Content type: Research article Published on:

  16. We performed a case–control study to estimate vaccine effectiveness (VE) for prevention of hospitalization due to pandemic influenza A(H1N1)pdm09 (pH1N1) and to identify risk factors for pH1N1 and acute respir...

    Authors: Wiebke Hellenbrand, Pernille Jorgensen, Brunhilde Schweiger, Gerhard Falkenhorst, Matthias Nachtnebel, Benedikt Greutélaers, Christian Traeder and Ole Wichmann
    Citation: BMC Infectious Diseases 2012 12:127
    Content type: Research article Published on:

  17. Although the prevalence of macrolide-resistant Mycoplasma pneumoniae isolates in Japanese pediatric patients has increased rapidly, there have been no reports concerning macrolide-resistant M. pneumoniae infectio...

    Authors: Naoyuki Miyashita, Yasuhiro Kawai, Hiroto Akaike, Kazunobu Ouchi, Toshikiyo Hayashi, Takeyuki Kurihara and Niro Okimoto
    Citation: BMC Infectious Diseases 2012 12:126
    Content type: Research article Published on:

  19. Pneumococcal conjugate vaccines (PCVs) are in the process of implementation in Latin America. Experience in developed countries has shown that they reduce the incidence of invasive and non-invasive disease. Ho...

    Authors: Elizabeth Castañeda, Clara Inés Agudelo, Rodrigo De Antonio, Diego Rosselli, Claudia Calderón, Eduardo Ortega-Barria and Rómulo E Colindres
    Citation: BMC Infectious Diseases 2012 12:124
    Content type: Research article Published on:

  20. Benznidazole (Bz)-chemotherapy is recommended to prevent Chagas disease progression, despite its limited efficacy during chronic disease. However, the host mechanisms underlying these benefits still remain to ...

    Authors: Renato Sathler-Avelar, Danielle Marquete Vitelli-Avelar, Silvana Maria Elói-Santos, Eliane Dias Gontijo, Andréa Teixeira-Carvalho and Olindo Assis Martins-Filho
    Citation: BMC Infectious Diseases 2012 12:123
    Content type: Research article Published on:

  21. Shigellosis is a major public health concern worldwide, especially in developing countries. It is an acute intestinal infection caused by bacteria of the genus Shigella, with a minimum infective dose as low as 10...

    Authors: Xiu Pei Koh, Chien Shun Chiou, Noni Ajam, Haruo Watanabe, Norazah Ahmad and Kwai Lin Thong
    Citation: BMC Infectious Diseases 2012 12:122
    Content type: Research article Published on:

  22. Miliary tuberculosis (TB) is an uncommon cause of acute respiratory distress syndrome (ARDS) with a high mortality. The aim of the present study was to evaluate the clinical characteristics, predictors and out...

    Authors: Wang Deng, Min Yu, Hilary Ma, Liang An Hu, Gang Chen, Yong Wang, Jia Deng, ChangYi Li, Jin Tong and Dao Xin Wang
    Citation: BMC Infectious Diseases 2012 12:121
    Content type: Research article Published on:

  23. Environmental surfaces play an important role in transmission of healthcare-associated pathogens. There is a need for new disinfection methods that are effective against Clostridium difficile spores, but also saf...

    Authors: Michelle M Nerandzic, Jennifer L Cadnum, Kevin E Eckart and Curtis J Donskey
    Citation: BMC Infectious Diseases 2012 12:120
    Content type: Research article Published on:

  24. Childhood pneumonia and bronchiolitis is a leading cause of illness and death in young children worldwide with Respiratory Syncytial Virus (RSV) as the main viral cause. RSV has been associated with annual res...

    Authors: Letícia Martins Lamarão, Francisco Luzio Ramos, Wyller Alencar Mello, Mirleide Cordeiro Santos, Luana Soares Barbagelata, Maria Cleonice Aguiar Justino, Alexandre Ferreira da Silva, Ana Judith Pires Garcia Quaresma, Veronilce Borges da Silva, Rommel Rodríguez Burbano and Alexandre Costa Linhares
    Citation: BMC Infectious Diseases 2012 12:119
    Content type: Research article Published on:

  26. Pneumonia is a leading cause of hospitalization during Hajj and susceptibility and transmission may be exacerbated by extreme spatial and temporal crowding. We describe the number and temporal onset, co–morbid...

    Authors: Yasser Mandourah, Assim Al-Radi, Ali Harold Ocheltree, Sara Rashid Ocheltree and Robert A Fowler
    Citation: BMC Infectious Diseases 2012 12:117
    Content type: Research article Published on:

  27. Extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae infections are associated with delayed initiation of appropriate treatment, poor outcomes and increased hospital stay and expense. Although initia...

    Authors: Jérôme Fennell, Akke Vellinga, Belinda Hanahoe, Dearbhaile Morris, Fiona Boyle, Francis Higgins, Maura Lyons, Karina O’Connell, Deirbhile Keady and Martin Cormican
    Citation: BMC Infectious Diseases 2012 12:116
    Content type: Research article Published on:

  28. Surgical site infection (SSI) are the third most frequently reported nosocomial infection, and the most common on surgical wards. HIV-infected patients may increase the possibility of developing SSI after surg...

    Authors: Lei Zhang, Bao-Chi Liu, Xiao-Yan Zhang, Lei Li, Xian-Jun Xia and Rui-Zhang Guo
    Citation: BMC Infectious Diseases 2012 12:115
    Content type: Research article Published on:

  29. Partner notification (PN) among individuals newly diagnosed with HIV/STI is seen as a vital tool to identify others at risk of infection. However, hardly any data are available on the effectiveness of PN on HI...

    Authors: Fleur van Aar, Imke Schreuder, Yolanda van Weert, Ralph Spijker, Hannelore Götz and Eline Op de Coul
    Citation: BMC Infectious Diseases 2012 12:114
    Content type: Research article Published on:

  30. Chlamydia trachomatis is a common sexually transmitted infection in Australia. This report aims to measure the burden of chlamydia infection by systematically reviewing reports on prevalence in Australian popula...

    Authors: Dyani Lewis, Danielle C Newton, Rebecca J Guy, Hammad Ali, Marcus Y Chen, Christopher K Fairley and Jane S Hocking
    Citation: BMC Infectious Diseases 2012 12:113
    Content type: Research article Published on:

  31. Genetic variation in immune response genes is associated with susceptibility and severity of infectious diseases. Toll-like receptor (TLR) 9 polymorphisms are associated with susceptibility to develop meningoc...

    Authors: Marieke S Sanders, Gijs TJ van Well, Sander Ouburg, Servaas A Morré and A Marceline van Furth
    Citation: BMC Infectious Diseases 2012 12:112
    Content type: Research article Published on:

  32. Treatment of shigellosis in rabbits with butyrate reduces clinical severity and counteracts the downregulation of cathelicidin (CAP-18) in the large intestinal epithelia. Here, we aimed to evaluate whether but...

    Authors: Rubhana Raqib, Protim Sarker, Akhirunnesa Mily, Nur Haque Alam, Abu Saleh Mohammed Arifuzzaman, Rokeya Sultana Rekha, Jan Andersson, Gudmundur H Gudmundsson, Alejandro Cravioto and Birgitta Agerberth
    Citation: BMC Infectious Diseases 2012 12:111
    Content type: Research article Published on:

  33. Varicella and herpes zoster are both caused by varicella zoster virus (VZV) infection or reactivation and may lead to complications associated with a (severe) societal burden. Because the epidemiology of VZV-r...

    Authors: Jorien GJ Pierik, Pearl D Gumbs, Sander AC Fortanier, Pauline CE Van Steenwijk and Maarten J Postma
    Citation: BMC Infectious Diseases 2012 12:110
    Content type: Research article Published on:

  34. The tcdA-negative variant (A-B+) of Clostridium difficile is prevalent in East Asian countries. However, the risk factors and clinical characteristics of A-B+ C. difficile infections (CDI) are not clearly documen...

    Authors: Jieun Kim, Hyunjoo Pai, Mi-ran Seo and Jung Oak Kang
    Citation: BMC Infectious Diseases 2012 12:109
    Content type: Research article Published on:

  35. Antibiotic associated diarrhoea complicates 5–39% of courses of antibiotic treatment. Major risk factors are increased age and admission to hospital. Of particular importance is C. difficile associated diarrhoea ...

    Authors: Stephen J Allen, Kathie Wareham, Caroline Bradley, Wyn Harris, Anjan Dhar, Helga Brown, Alwyn Foden, Way Yee Cheung, Michael B Gravenor, Sue Plummer, Ceri J Phillips and Dietrich Mack
    Citation: BMC Infectious Diseases 2012 12:108
    Content type: Study protocol Published on:

  38. Authors: A Ashwin, Febe R Suman, Vinod K Panicker, S Alexander and R Krishnamoorthy
    Citation: BMC Infectious Diseases 2012 12(Suppl 1):P81
    Content type: Poster presentation Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  46. Authors: Rajesh Kumar, Raiees Andrabi, Ashutosh Tiwari, Somi Sankaran Prakash, Naveet Wig, Durgashree Dutta, Anurag Sankhyan, Lubina Khan, Subrata Sinha and Kalpana Luthra
    Citation: BMC Infectious Diseases 2012 12(Suppl 1):P11
    Content type: Poster presentation Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

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