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  1. Research article

    Acute undifferentiated fever in India: a multicentre study of aetiology and diagnostic accuracy

    The objectives of this study were to determine the proportion of malaria, bacteraemia, scrub typhus, leptospirosis, chikungunya and dengue among hospitalized patients with acute undifferentiated fever in India...

    Kristine Mørch, Anand Manoharan, Sara Chandy, Novin Chacko, Gerardo Alvarez-Uria, Suvarna Patil, Anil Henry, Joel Nesaraj, Cijoy Kuriakose, Ashita Singh, Siby Kurian, Christel Gill Haanshuus, Nina Langeland, Bjørn Blomberg, George Vasanthan Antony and Dilip Mathai

    BMC Infectious Diseases 2017 17:665

    Published on: 4 October 2017

  2. Research article

    Group B streptococcus (GBS) is an important pathogen in human disease- but what about in cystic fibrosis?

    Group B Streptococcus (GBS) is a common commensal capable of causing severe invasive infections. Most GBS infections occur in neonates (often as pneumonia). GBS can also cause infection in adults with diabetes...

    Kate Skolnik, Austin Nguyen, Christina S. Thornton, Barbara Waddell, Tyler Williamson, Harvey R. Rabin and Michael D. Parkins

    BMC Infectious Diseases 2017 17:660

    Published on: 2 October 2017

  3. Research article

    Five-year trends in treatment changes in an adult cohort of HIV/AIDS patients in Ghana: a retrospective cohort study

    There is limited information on patterns of treatment change among new initiators of highly active antiretroviral therapy (HAART) in the regions most affected by HIV/AIDS. This makes it difficult to identify t...

    Daniel N. A. Ankrah, Margaret Lartey, Aukje K. Mantel-Teeuwisse and Hubert G. M. Leufkens

    BMC Infectious Diseases 2017 17:664

    Published on: 2 October 2017

  4. Research article

    Investigation of Salmonella Enteritidis outbreaks in South Africa using multi-locus variable-number tandem-repeats analysis, 2013-2015

    Salmonella enterica serovar Enteritidis (Salmonella Enteritidis) has become a significant pathogen in South Africa, and the need for improved molecular surveillance of this pathogen ha...

    Munyadziwa Muvhali, Anthony Marius Smith, Andronica Moipone Rakgantso and Karen Helena Keddy

    BMC Infectious Diseases 2017 17:661

    Published on: 2 October 2017

  5. Technical advance

    Evaluation of Mycobacterium tuberculosis viability in OMNIgene-SPUTUM reagent upon multi-day transport at ambient temperature

    Maintaining the quality of clinical specimens for tuberculosis (TB) testing is a major challenge in many high TB burden-limited resources countries. Sample referral systems in low and middle income countries a...

    Elisa Tagliani, Riccardo Alagna, Silva Tafaj, Hasan Hafizi and Daniela Maria Cirillo

    BMC Infectious Diseases 2017 17:663

    Published on: 2 October 2017

  6. Research article

    A dual regimen of ritonavir/darunavir plus dolutegravir for rescue or simplification of rescue therapy: 48 weeks’ observational data

    Dolutegravir (DTG) plus darunavir/ritonavir (DRV/r) is a simple combination of drugs that has the best genetic barrier to HIV-1 resistance and may be fit for salvage therapy.

    Amedeo F. Capetti, Maria Vittoria Cossu, Giancarlo Orofino, Gaetana Sterrantino, Giovanni Cenderello, Giuseppe V. De Socio, Anna Maria Cattelan, Alessandro Soria, Stefano Rusconi, Niccolò Riccardi, Gian Maria Baldin, Fosca P. Niero, Giorgio Barbarini and Giuliano Rizzardini

    BMC Infectious Diseases 2017 17:658

    Published on: 30 September 2017

  7. Research article

    Risk factors for multidrug-resistant pathogens in bronchiectasis exacerbations

    Non-cystic fibrosis bronchiectasis is a chronic structural lung condition that courses with recurrent infectious exacerbations that lead to frequent antibiotic treatment making this population more susceptible...

    Rosario Menéndez, Raúl Méndez, Eva Polverino, Edmundo Rosales-Mayor, Isabel Amara-Elori, Soledad Reyes, José Miguel Sahuquillo-Arce, Laia Fernández-Barat, Victoria Alcaraz and Antoni Torres

    BMC Infectious Diseases 2017 17:659

    Published on: 30 September 2017

  8. Research article

    Predictors of unsuccessful interim treatment outcomes of multidrug resistant tuberculosis patients

    Interim treatment outcomes at 6-months for multidrug-resistant tuberculosis (MDR-TB) treatment are among the most basic performance monitoring and key evaluation indicators in the Stop and End TB strategy of t...

    Muhammad Atif, Arslan Bashir, Nafees Ahmad, Razia Kaneez Fatima, Sehar Saba and Shane Scahill

    BMC Infectious Diseases 2017 17:655

    Published on: 29 September 2017

  9. Research article

    Community-based surveillance of norovirus disease: a systematic review

    Norovirus is a common cause of infectious gastrointestinal disease. Despite the increased ability to detect norovirus in affected people, the number of reported cases and outbreaks in the community is still su...

    Thomas Inns, John Harris, Roberto Vivancos, Miren Iturriza-Gomara and Sarah O’Brien

    BMC Infectious Diseases 2017 17:657

    Published on: 29 September 2017

  10. Research article

    Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: phenotypic and genotypic analysis of isolates

    Workers in clinical microbiology laboratories are exposed to a variety of pathogenic microorganisms. Salmonella species is among the most commonly reported bacterial causes of laboratory-acquired infections. We r...

    Anthony Marius Smith, Shannon Lucrecia Smouse, Nomsa Pauline Tau, Colleen Bamford, Vineshree Mischka Moodley, Charlene Jacobs, Kerrigan Mary McCarthy, Adré Lourens and Karen Helena Keddy

    BMC Infectious Diseases 2017 17:656

    Published on: 29 September 2017

  11. Research article

    Protocol and baseline data for a multi-year cohort study of the effects of different mass drug treatment approaches on functional morbidities from schistosomiasis in four African countries

    The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) focus is on randomized trials of different approaches to mass drug administration (MDA) in endemic countries in Africa. Because th...

    Ye Shen, Charles H. King, Sue Binder, Feng Zhang, Christopher C. Whalen, W. Evan Secor, Susan P. Montgomery, Pauline N. M. Mwinzi, Annette Olsen, Pascal Magnussen, Safari Kinung’hi, Anna E. Phillips, Rassul Nalá, Josefo Ferro, H. Osvaldo Aurelio, Fiona Fleming…

    BMC Infectious Diseases 2017 17:652

    Published on: 29 September 2017

  12. Research article

    Angiopoietin-like protein as a novel marker for liver fibrosis in chronic hepatitis B patients with normal to minimally raised ALT

    For hepatitis B patients who do not meet the treatment criteria recommended by guidelines, therapy decisions depend on hepatic histology. Angiopoietin-like protein 2 (Angptl2) is a mediator of chronic inflamma...

    Yongqiong Deng, Hong Zhao, Jiyuan Zhou, Linlin Yan and Guiqiang Wang

    BMC Infectious Diseases 2017 17:650

    Published on: 29 September 2017

  13. Research article

    A comparison of self-report and antiretroviral detection to inform estimates of antiretroviral therapy coverage, viral load suppression and HIV incidence in Kwazulu-Natal, South Africa

    Accurately identifying individuals who are on antiretroviral therapy (ART) is important to determine ART coverage and proportion on ART who are virally suppressed. ART is also included in recent infection test...

    Helena Huerga, Fisseha Shiferie, Eduard Grebe, Ruggero Giuliani, Jihane Ben Farhat, Gilles Van-Cutsem and Karen Cohen

    BMC Infectious Diseases 2017 17:653

    Published on: 29 September 2017

  14. Research article

    B-type brain natriuretic peptide as a measure of the severity of hand-foot-mouth disease: a case-control study

    Hand-foot-mouth disease (HFMD) is an acute infectious disease caused by enteroviruses, and HFMD complicated by cardiopulmonary failure has a high mortality. B type natriuretic peptide (BNP) is widely applied i...

    AYuan Zhang, Lin Yang, Pengfei Guo, Shaojun Li, Xiaoxiao Ao, Feng Xu and Liping Tan

    BMC Infectious Diseases 2017 17:651

    Published on: 29 September 2017

  15. Case report

    Orbital apex syndrome secondary to a fungal nasal septal abscess caused by Scedosporium apiospermum in a patient with uncontrolled diabetes: a case report

    Orbital apex syndrome is a localized type of orbital cellulitis, where mass lesions occur at the apex of the cranial nerves. Although nasal septal abscess is uncommon, the organism most likely to cause nasal s...

    Ippei Kishimoto, Shogo Shinohara, Tetsuhiro Ueda, Shoichi Tani, Hajime Yoshimura and Yukihiro Imai

    BMC Infectious Diseases 2017 17:649

    Published on: 26 September 2017

  16. Research article

    Possible explanations for why some countries were harder hit by the pandemic influenza virus in 2009 – a global mortality impact modeling study

    A global pandemic mortality study found prominent regional mortality variations in 2009 for Influenza A(H1N1)pdm09. Our study attempts to identify factors that explain why the pandemic mortality burden was hig...

    Kathleen F. Morales, John Paget and Peter Spreeuwenberg

    BMC Infectious Diseases 2017 17:642

    Published on: 25 September 2017

  17. Research article

    Spatio-temporal clustering analysis and its determinants of hand, foot and mouth disease in Hunan, China, 2009–2015

    Hand, foot and mouth disease (HFMD) is one of the highest reported infectious diseases with several outbreaks across the world. This study aimed at describing epidemiological characteristics, investigating spa...

    Xinrui Wu, Shixiong Hu, Abuaku Benjamin Kwaku, Qi Li, Kaiwei Luo, Ying Zhou and Hongzhuan Tan

    BMC Infectious Diseases 2017 17:645

    Published on: 25 September 2017

  18. Study protocol

    Rationale and design of ASPIRE-ICU: a prospective cohort study on the incidence and predictors of Staphylococcus aureus and Pseudomonas aeruginosa pneumonia in the ICU

    The epidemiology of ICU pneumonia caused by Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) is not fully described, but is urgently needed to support the development of effective inte...

    Fleur P. Paling, Darren P. R. Troeman, Martin Wolkewitz, Rubana Kalyani, Daniël R. Prins, Susanne Weber, Christine Lammens, Leen Timbermont, Herman Goossens, Surbhi Malhotra-Kumar, Frangiscos Sifakis, Marc J. M. Bonten and Jan A. J. W. Kluytmans

    BMC Infectious Diseases 2017 17:643

    Published on: 25 September 2017

  19. Case report

    Bordetella bronchiseptica pneumonia in a patient with lung cancer; a case report of a rare infection

    Bordetella bronchiseptica (B.bronchiseptica) is a frequent cause of respiratory infections in animals but rarely causes serious infection in humans. We present a rare case of B. bronch...

    Manlio Monti, Danila Diano, Francesco Allegrini, Angelo Delmonte, Valentina Fausti, Paola Cravero, Giulia Marcantognini and Giovanni Luca Frassineti

    BMC Infectious Diseases 2017 17:644

    Published on: 25 September 2017

  20. Research article

    Long-term outcome in survivors of neonatal tetanus following specialist intensive care in Vietnam

    Neonatal tetanus continues to occur in many resource-limited settings but there are few data regarding long-term neurological outcome from the disease, especially in settings with critical care facilities.

    Huynh T. Trieu, Nguyen Thi Kim Anh, Huynh Ngoc Thien Vuong, T. T. M. Dao, Nguyen Thi Xuan Hoa, Vo Ngoc Cat Tuong, Pham Tam Dinh, Bridget Wills, Phan Tu Qui, Le Van Tan, Lam Minh Yen, Saraswathy Sabanathan and Catherine Louise Thwaites

    BMC Infectious Diseases 2017 17:646

    Published on: 25 September 2017

  21. Research article

    Modifiable risk factors for typhoid intestinal perforations during a large outbreak of typhoid fever, Kampala Uganda, 2015

    Between January and June, 2015, a large typhoid fever outbreak occurred in Kampala, Uganda, with 10,230 suspected cases. During the outbreak, area surgeons reported a surge in cases of typhoid intestinal perfo...

    Lilian Bulage, Ben Masiira, Alex R. Ario, Joseph K.B Matovu, Peter Nsubuga, Frank Kaharuza, Victoria Nankabirwa, Janell Routh and Bao-Ping Zhu

    BMC Infectious Diseases 2017 17:641

    Published on: 25 September 2017

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