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  1. Nitroxoline, a hydroxychinoline derivate, has been used for many years to treat urinary tract infections (UTI). Many uncontrolled, but only few controlled clinical studies have been published. Four so far unpu...

    Authors: Kurt G Naber, Hiltrud Niggemann, Gisela Stein and Guenter Stein
    Citation: BMC Infectious Diseases 2014 14:628
    Content type: Research article Published on:

  2. Evolving gonococcal antimicrobial resistance (AMR) poses a serious threat to public health. The aim of this study was to: update antimicrobial susceptibility data of Neisseria gonorrhoeae recently isolated in Nan...

    Authors: Sai Li, Xiao-Hong Su, Wen-Jing Le, Fa-Xing Jiang, Bao-Xi Wang and Peter A Rice
    Citation: BMC Infectious Diseases 2014 14:622
    Content type: Research article Published on:

  3. Prosthetic joint infection (PJI) due to Salmonella is rare. Numerous outbreaks of Salmonella have been reported throughout the United States in the last decade. We reviewed and analyzed cases of Salmonella PJI se...

    Authors: Arjun Gupta, Elie F Berbari, Douglas R Osmon and Abinash Virk
    Citation: BMC Infectious Diseases 2014 14:633
    Content type: Research article Published on:

  4. Viral central nervous system (CNS) infections are common in countries where malaria is endemic but, due to limited laboratory facilities, few studies have systematically examined the prevalence and clinical co...

    Authors: Moses Laman, Ilomo Hwaiwhanje, Cathy Bona, Jonathan Warrel, Susan Aipit, David Smith, Joanna Noronha, Peter Siba, Ivo Mueller, Inoni Betuela, Timothy ME Davis and Laurens Manning
    Citation: BMC Infectious Diseases 2014 14:630
    Content type: Research article Published on:

  5. Clostridium difficile infection (CDI) remains a major health problem worldwide. Antibiotic use, in general, and clindamycin and ciprofloxacin, in particular, have been implicated in the pathogenesis of CDI. Here...

    Authors: Andrea C Büchler, Silvana K Rampini, Simon Stelling, Bruno Ledergerber, Silke Peter, Alexander Schweiger, Christian Ruef, Reinhard Zbinden and Roberto F Speck
    Citation: BMC Infectious Diseases 2014 14:607
    Content type: Research article Published on:

  6. Acute Aspergillus fumigatus infection in immunocompetent patients is rare. This is the first known case of a patient who survived Aspergillus sepsis after being treated early with veno-venous extracorporeal membr...

    Authors: Nina Jung, Silke Mronga, Susanne Schroth, Timon Vassiliou, Frank Sommer, Eduard Walthers, Christian Aepinus, Andreas Jerrentrup, Claus Vogelmeier, Angelique Holland and Rembert Koczulla
    Citation: BMC Infectious Diseases 2014 14:600
    Content type: Case report Published on:

  7. From 2007 to 2010, (the southern part of) the Netherlands experienced a large Q fever epidemic, with more than 4,000 reported symptomatic cases. Approximately 1 - 5% of the acute Q fever patients develop chron...

    Authors: Rana Jajou, Cornelia Christina Henrica Wielders, Monique Leclercq, Jeroen van Leuken, Shahan Shamelian, Nicole Renders, Wim van der Hoek and Peter Schneeberger
    Citation: BMC Infectious Diseases 2014 14:629
    Content type: Research article Published on:

  8. Early diagnosis and prompt effective therapy are crucial for the prevention of tuberculosis (TB) transmission, particularly in regions with high levels of multi-drug resistant TB. This study aimed to evaluate ...

    Authors: Tatiana V Belkina, Doniyor S Khojiev, Mirzagaleb N Tillyashaykhov, Zinaida N Tigay, Marat U Kudenov, Jurjen Duintjer Tebbens and Jiri Vlcek
    Citation: BMC Infectious Diseases 2014 14:624
    Content type: Research article Published on:

  9. Clinical differentiation of influenza from dengue and other febrile illnesses (OFI) is difficult, and available rapid diagnostic tests have limited sensitivity.

    Authors: Shi-Yu Huang, Ing-Kit Lee, Lin Wang, Jien-Wei Liu, Shih-Chiang Hung, Chien-Chih Chen, Tzu-Yao Chang and Wen-Chi Huang
    Citation: BMC Infectious Diseases 2014 14:623
    Content type: Research article Published on:

  10. The protozoan parasite Entamoeba histolytica (E. histolytica) usually asymptomatically colonizes the human intestine. In the minority of the cases, the parasite evades from the gut and can induce severe symptoms ...

    Authors: Hannah Bernin, Claudia Marggraff, Thomas Jacobs, Norbert Brattig, Le Van An, Jörg Blessmann and Hannelore Lotter
    Citation: BMC Infectious Diseases 2014 14:621
    Content type: Research article Published on:

  11. A previously published proof of principle phase IIa trial with 113 patients from Kabul showed that bipolar high-frequency (HF) electro-cauterization (EC) of cutaneous leishmaniasis (CL) ulcers and subsequent m...

    Authors: Hans-Christian Stahl, Faridullah Ahmadi, Ulrike Schleicher, Rainer Sauerborn, Justo Lorenzo Bermejo, Mohammed Latif Amirih, Ibrahim Sakhayee, Christian Bogdan and Kurt-Wilhelm Stahl
    Citation: BMC Infectious Diseases 2014 14:619
    Content type: Research article Published on:

  13. The widespread use of empiric broad spectrum antibiotics has contributed to the global increase of Resistant Gram-Negative Bacilli (RGNB) infections in intensive care units (ICU). The aim of this study was to ...

    Authors: Anupama Vasudevan, Amartya Mukhopadhyay, Jialiang Li, Eugene Goh Yu Yuen and Paul Ananth Tambyah
    Citation: BMC Infectious Diseases 2014 14:615
    Content type: Research article Published on:

  14. Dengue fever, a mosquito-borne viral disease, is a rapidly emerging public health problem in Ecuador and throughout the tropics. However, we have a limited understanding of the disease transmission dynamics in...

    Authors: Anna M Stewart-Ibarra, Ángel G Muñoz, Sadie J Ryan, Efraín Beltrán Ayala, Mercy J Borbor-Cordova, Julia L Finkelstein, Raúl Mejía, Tania Ordoñez, G Cristina Recalde-Coronel and Keytia Rivero
    Citation: BMC Infectious Diseases 2014 14:610
    Content type: Research article Published on:

  15. The elderly patients affected by candidemia are growing in proportion to inpatients, but available data are limited. We aimed to determine the epidemiology, antifungal management and clinical risk factors of d...

    Authors: Hao Wang, Naizheng Liu, Mei Yin, Hui Han, Jinfeng Yue, Fan Zhang, Tichao Shan, Haipeng Guo and Dawei Wu
    Citation: BMC Infectious Diseases 2014 14:609
    Content type: Research article Published on:

  16. Major hospitals in most Chinese cities have the capability to perform HIV testing. However, it is not a routine test for all patients and, as a result, many patients are not aware of their HIV status. To under...

    Authors: Hua-Feng Xu, Hai-Zhou Zhou, Li-Xin Jiang, Na Zhang, Xuan Zhang and Xiu-Ru Guan
    Citation: BMC Infectious Diseases 2014 14:605
    Content type: Research article Published on:

  17. UNAIDS has called for greater HIV/syphilis testing worldwide just as local HIV/syphilis testing programs are cut or altered. New models are needed to make HIV/syphilis testing services sustainable while retain...

    Authors: Joseph D Tucker, Kathryn E Muessig, Rosa Cui, Cedric H Bien, Elaine J Lo, Ramon Lee, Kaidi Wang, Larry Han, Feng-Ying Liu, Li-Gang Yang, Bin Yang, Heidi Larson and Rosanna W Peeling
    Citation: BMC Infectious Diseases 2014 14:601
    Content type: Research article Published on:

  18. A rapid, sensitive and accurate laboratory diagnosis is of prime importance in suspected extrapulmonary tuberculosis (EPTB) cases. However, traditional techniques for the detection of acid-fast bacilli have li...

    Authors: Agerie Tadele, Demissew Beyene, Jemal Hussein, Tuffa Gemechu, Asaye Birhanu, Tehmina Mustafa, Aster Tsegaye, Abraham Aseffa and Lisbet Sviland
    Citation: BMC Infectious Diseases 2014 14:585
    Content type: Research article Published on:

  19. Malaria during pregnancy remains a serious public health problem. The aim of this study was to determine the prevalence and possible risk factors for malaria in pregnant women attending antenatal clinic at two...

    Authors: Mamoudou Cisse, Ibrahim Sangare, Guekoun Lougue, Sanata Bamba, Dramane Bayane and Robert Tinga Guiguemde
    Citation: BMC Infectious Diseases 2014 14:631
    Content type: Research article Published on:

  20. Refining the spatial and temporal data on malaria transmissions at a defined ecological setting has practical implications for targeted malaria control and enhancing efficient allocation of resources. Spatial ...

    Authors: Lelisa Sena, Wakgari Deressa and Ahmed Ali
    Citation: BMC Infectious Diseases 2014 14:625
    Content type: Research article Published on:

  21. Tuberculosis (TB) during pregnancy may lead to severe consequences affecting both mother and child. Prenatal care could be a very good opportunity for TB care, especially for women who have limited access to h...

    Authors: Hang Thanh Nguyen, Chiara Pandolfini, Peter Chiodini and Maurizio Bonati
    Citation: BMC Infectious Diseases 2014 14:617
    Content type: Research article Published on:

  22. Tétanos Quick Stick® (TQS) is a test for tetanus immunity screening for wounded patients in emergency departments (EDs), but represents additional costs compared with a medical interview on vaccination history...

    Authors: Dieynaba S N'Diaye, Michaël Schwarzinger, Dorothée Obach, Julien Poissy, Sophie Matheron, Enrique Casalino and Yazdan Yazdanpanah
    Citation: BMC Infectious Diseases 2014 14:603
    Content type: Research article Published on:

  23. We aimed to investigate the molecular epidemiology of Mycobacterium tuberculosis complex (MTBC) isolates in the province of Palermo, Sicily, Italy, by characterizing 183 isolates identified in the years 2004-2012...

    Authors: Celestino Bonura, Michel K Gomgnimbou, Guislaine Refrégier, Aurora Aleo, Teresa Fasciana, Anna Giammanco, Christophe Sola and Caterina Mammina
    Citation: BMC Infectious Diseases 2014 14:602
    Content type: Research article Published on:

  24. Non-tuberculous mycobacteria (NTM), which are ubiquitous micro-organisms occurring in humans, animals and the environment, sometimes receive public health and veterinary attention as opportunistic disease-caus...

    Authors: Bugwesa Z Katale, Erasto V Mbugi, Louise Botha, Julius D Keyyu, Sharon Kendall, Hazel M Dockrell, Anita L Michel, Rudovick R Kazwala, Mark M Rweyemamu, Paul van Helden and Mecky I Matee
    Citation: BMC Infectious Diseases 2014 14:616
    Content type: Research article Published on:

  25. Tick borne encephalitis is the most frequent vector-transmitted infectious disease of the central nervous system in Europe and Asia. The disease caused by European subtype of tick borne encephalitis virus has ...

    Authors: Daša Stupica, Franc Strle, Tatjana Avšič-Županc, Mateja Logar, Blaž Pečavar and Fajko F Bajrović
    Citation: BMC Infectious Diseases 2014 14:614
    Content type: Case report Published on:

  26. Global health investment has reduced HIV mortality and transmission. However, little is known of patient-reported outcomes alongside ART rollout. This study aimed to measure wellbeing using patient-reported ou...

    Authors: Richard Harding, Victoria Simms, Suzanne Penfold, Julia Downing, Eve Namisango, Richard A Powell, Faith Mwangi-Powell, Scott Moreland, Nancy Gikaara, Mackuline Atieno and Irene J Higginson
    Citation: BMC Infectious Diseases 2014 14:613
    Content type: Research article Published on:

  27. Internet-based Chlamydia Screening Implementation (chlamydia screening programme) was introduced in the Netherlands in 2008-2010 to detect and treat asymptomatic infections and to limit ongoing transmission th...

    Authors: Geneviève AFS van Liere, Nicole HTM Dukers-Muijrers, Jan EAM van Bergen, Hannelore M Götz, Frans Stals and Christian JPA Hoebe
    Citation: BMC Infectious Diseases 2014 14:612
    Content type: Research article Published on:

  28. Despite universal recognition of the importance of hand hygiene in reducing the incidence of healthcare associated infections, health care workers’ compliance with best practice has been sub-optimal. Senior ho...

    Authors: Elizabeth McInnes, Rosemary Phillips, Sandy Middleton and Dinah Gould
    Citation: BMC Infectious Diseases 2014 14:611
    Content type: Research article Published on:

  30. Up to 20% of all infective endocarditis are blood culture-negative and therefore a diagnostic challenge. Here we present the case of an infective endocarditis due to Helicobacter cinaedi finally diagnosed using d...

    Authors: Hanni Bartels, Daniel Goldenberger, Oliver Reuthebuch, Juerg Vosbeck, Maja Weisser, Reno Frei and Veronika Bättig
    Citation: BMC Infectious Diseases 2014 14:586
    Content type: Case report Published on:

  31. Immunity plays an important role in controlling human papillomavirus (HPV) infection and associated lesions. Unlike infections caused by other viruses, natural HPV infection does not always result in a protect...

    Authors: Patrícia S de Araujo-Souza, Agnihotram V Ramanakumar, João M G Candeias, Patrícia Thomann, Andrea Trevisan, Eduardo L Franco and Luisa L Villa
    Citation: BMC Infectious Diseases 2014 14:578
    Content type: Research article Published on:

  32. India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a targ...

    Authors: Dharma Rao Uppada, Sumithra Selvam, Nelson Jesuraj, Sean Bennett, Suzanne Verver, Harleen MS Grewal and Mario Vaz
    Citation: BMC Infectious Diseases 2014 14:571
    Content type: Research article Published on:

  33. The diagnosis and treatment of latent tuberculosis infection (LTBI) have become mandatory to reduce the burden of tuberculosis worldwide. Close contacts of active TB patients are at high risk of both active an...

    Authors: Seung Jun Lee, Seung Hun Lee, You Eun Kim, Yu Ji Cho, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee, Jang Rak Kim, Young Sil Hwang, Hee Jin Kim and Dick Menzies
    Citation: BMC Infectious Diseases 2014 14:566
    Content type: Research article Published on:

  35. Our aim is to detect the infection by Toscana virus (TOSV) and other Phleboviruses in the sera and cerebro-spinal fluid (CSF) of patients with meningitis in Tunisia. We examined various species of phlebotomus ...

    Authors: Ons Fezaa, Youmna M’ghirbi, Gianni Gori Savellini, Lamia Ammari, Nahed Hogga, Henda Triki, Maria Grazia Cusi and Ali Bouattour
    Citation: BMC Infectious Diseases 2014 14:598
    Content type: Research article Published on:

  36. Environmental monitoring of airborne filamentous fungi is necessary to reduce fungal concentrations in operating theaters and in controlled environments, and to prevent infections. The present study reports re...

    Authors: Giuseppina Caggiano, Christian Napoli, Caterina Coretti, Grazia Lovero, Giancarlo Scarafile, Osvalda De Giglio and Maria Teresa Montagna
    Citation: BMC Infectious Diseases 2014 14:595
    Content type: Research article Published on:

  37. The clinical course of Staphylococcus aureus bloodstream infection is unpredictable and bacterial virulence, host immune response and patient characteristics are among the factors that contribute to the clinical ...

    Authors: Sinead McNicholas, Alida Fe Talento, Joanne O’Gorman, Margaret M Hannan, Maureen Lynch, Catherine M Greene, Hilary Humphreys and Deirdre Fitzgerald-Hughes
    Citation: BMC Infectious Diseases 2014 14:580
    Content type: Research article Published on:

  38. Guidelines for antiretroviral treatment (cART) are published regularly, but there is little information regarding the effect of adherence to guidelines on patient outcomes. We assessed the effect of following ...

    Authors: Laurent Cotte, Thomas Bénet, Philippe Vanhems, Corinne Brochier, Thomas Perpoint, Tristan Ferry and Christian Chidiac
    Citation: BMC Infectious Diseases 2014 14:596
    Content type: Research article Published on:

  39. We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause of nosocomial infection, in South Korea.

    Authors: Chung-Jong Kim, Hong-Bin Kim, Myoung-don Oh, Yunhee Kim, Arim Kim, Sung-Hee Oh, Kyoung-Ho Song, Eu Suk Kim, Yong Kyun Cho, Young Hwa Choi, Jinyong Park, Baek-Nam Kim, Nam-Joong Kim, Kye-Hyung Kim, Eun Jung Lee, Jae-Bum Jun…
    Citation: BMC Infectious Diseases 2014 14:590
    Content type: Research article Published on:

  40. The Xpert MTB/RIF assay (Xpert assay; Cepheid, Sunnyvale, CA) is becoming the test of choice for the rapid diagnosis of tuberculosis and rifampin (RIF) resistance. The aim of this study was to evaluate the per...

    Authors: Hee Jae Huh, Byeong-Ho Jeong, Kyeongman Jeon, Won-Jung Koh, Chang-Seok Ki and Nam Yong Lee
    Citation: BMC Infectious Diseases 2014 14:589
    Content type: Research article Published on:

  41. World Health Organization (WHO) has recommended individuals with increased risk of contracting influenza A H5N1 infection to be immunized against the virus during the inter-pandemic period. Safety and immunoge...

    Authors: Sung-Hsi Wei, Ming-Tsan Liu, Yao-Chou Tsai, Chung-Hsin Liao, Chih-Ming Chen, Wei-Yao Wang, Yi-Lung Huang, Feng-Yee Chang and Pesus Chou
    Citation: BMC Infectious Diseases 2014 14:587
    Content type: Research article Published on:

  42. In patients hospitalized in intensive care units (ICU), Candida infections are associated with increased morbidity, mortality and costs. However, previous studies reported confused risk factors for catheter-relat...

    Authors: Bo Hu, Zhaohui Du, Yan Kang, Bin Zang, Wei Cui, Bingyu Qin, Qiang Fang, Haibo Qiu and Jianguo Li
    Citation: BMC Infectious Diseases 2014 14:594
    Content type: Research article Published on:

  43. Infection by pathogenic viruses results in rapid epithelial damage and significantly impacts on the condition of the upper respiratory tract, thus the effects of viral infection may induce changes in microbiot...

    Authors: Hana Yi, Dongeun Yong, Kyungwon Lee, Yong-Joon Cho and Jongsik Chun
    Citation: BMC Infectious Diseases 2014 14:583
    Content type: Research article Published on:

  44. To better understand potential transmission risks from contact with the body fluids of children, we monitored the presence and amount of CMV shedding over time in healthy CMV-seropositive children.

    Authors: Michael J Cannon, Jennifer D Stowell, Rebekah Clark, Philip R Dollard, Delaney Johnson, Karen Mask, Cynthia Stover, Karen Wu, Minal Amin, Will Hendley, Jing Guo, D Scott Schmid and Sheila C Dollard
    Citation: BMC Infectious Diseases 2014 14:569
    Content type: Research article Published on:

  45. Chlamydia trachomatis is a pathogen of worldwide importance, causing more than 100 million cases of sexually transmitted infections annually. Whole-genome sequencing is a powerful high resolution tool that can b...

    Authors: Mette T Christiansen, Amanda C Brown, Samit Kundu, Helena J Tutill, Rachel Williams, Julianne R Brown, Jolyon Holdstock, Martin J Holland, Simon Stevenson, Jayshree Dave, CY William Tong, Katja Einer-Jensen, Daniel P Depledge and Judith Breuer
    Citation: BMC Infectious Diseases 2014 14:591
    Content type: Research article Published on:

  46. Fusarium species are among the most common fungi present in the environment and some species have emerged as major opportunistic fungal infection in human. However, in immunocompromised hosts they can be virulen...

    Authors: Abdullah M S Al-Hatmi, Alexandro Bonifaz, G Sybren de Hoog, Leticia Vazquez-Maya, Karla Garcia-Carmona, Jacques F Meis and Anne D van Diepeningen
    Citation: BMC Infectious Diseases 2014 14:588
    Content type: Research article Published on:

  47. Congenital cytomegalovirus (CMV) is the leading infectious cause of birth defects in the United States. To better understand factors that may influence CMV transmission risk, we compared viral and immunologica...

    Authors: Jennifer D Stowell, Karen Mask, Minal Amin, Rebekah Clark, Denise Levis, Will Hendley, Tatiana M Lanzieri, Sheila C Dollard and Michael J Cannon
    Citation: BMC Infectious Diseases 2014 14:568
    Content type: Research article Published on:

  48. The goal was to determine whether one medical centres’ unique antifungal prophylactic regimen for patients at high risk for invasive candidiasis because of their haematological malignancies, haematopoietic ste...

    Authors: Danielle Vuichard, Maja Weisser, Christina Orasch, Reno Frei, Dominik Heim, Jakob R Passweg and Andreas F Widmer
    Citation: BMC Infectious Diseases 2014 14:573
    Content type: Research article Published on:

  49. Iatrogenic skin and soft tissue infections by rapidly growing mycobacteria are described with increasing frequency, especially among immunocompromised patients.

    Authors: Nguyen Phu Huong Lan, Marion-Eliëtte Kolader, Nguyen Van Dung, James I Campbell, Nguyen thi Tham, Nguyen Van Vinh Chau, H Rogier van Doorn and Dien Hoa Le
    Citation: BMC Infectious Diseases 2014 14:550
    Content type: Case report Published on:

  50. In Italy, free-of-charge HPV vaccination is offered to 11-year-old girls since 2007. The National Immunization Plan established the target coverage at a minimum of 70%; it should increase to 95% within 3-year ...

    Authors: Cristina Giambi, Fortunato D'Ancona, Martina Del Manso, Barbara De Mei, Ilaria Giovannelli, Chiara Cattaneo, Valentina Possenti and Silvia Declich
    Citation: BMC Infectious Diseases 2014 14:545
    Content type: Research article Published on:

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BMC Infectious Diseases

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