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  1. The recent emergence of Clostridium difficile infections has included this condition among top nosocomial infections, due to its incidence, complications and important fatality, as well as to significant economic...

    Authors: Ruxandra Laza, Ruxandra Jurac, Alexandru Crişan, Voichiţa Lăzureanu, Monica Licker, Emilian Damian Popovici and Luminiţa Mirela Bădiţoiu
    Citation: BMC Infectious Diseases 2015 15:141
    Content type: Research article Published on:

  2. Elderly people are at increased risk for severe influenza illness and constitute therefore a major target-group for seasonal influenza vaccination in most industrialized countries. The aim of this study was to...

    Authors: Cornelius Remschmidt, Thorsten Rieck, Birte Bödeker and Ole Wichmann
    Citation: BMC Infectious Diseases 2015 15:137
    Content type: Research article Published on:

  3. Some studies have suggested that helminth infections increase the risk of malaria infection and are associated with increased number of malaria attacks and anaemia. Thus interventions to control helminth infec...

    Authors: Safari M Kinung’hi, Pascal Magnussen, Coleman Kishamawe, Jim Todd and Birgitte J Vennervald
    Citation: BMC Infectious Diseases 2015 15:136
    Content type: Research article Published on:

  4. Infectious disease surveillance has recently seen many changes including rapid growth of informal surveillance, acting both as competitor and a facilitator to traditional surveillance, as well as the implement...

    Authors: Chi Y Bahk, David A Scales, Sumiko R Mekaru, John S Brownstein and Clark C Freifeld
    Citation: BMC Infectious Diseases 2015 15:135
    Content type: Research article Published on:

  5. Recently we developed and validated generic quality indicators that define ‘appropriate antibiotic use’ in hospitalized adults treated for a (suspected) bacterial infection. Previous studies have shown that wi...

    Authors: Frederike V van Daalen, Jan M Prins, Brent C Opmeer, Marja A Boermeester, Caroline E Visser, Reinier M van Hest, Marlies E J L Hulscher and Suzanne E Geerlings
    Citation: BMC Infectious Diseases 2015 15:134
    Content type: Study protocol Published on:

  6. Insulin resistance is a strong predictor of the development of type 2 diabetes mellitus. Chronic helminth infections might protect against insulin resistance via a caloric restriction state and indirectly via ...

    Authors: Dicky L Tahapary, Karin de Ruiter, Ivonne Martin, Lisette van Lieshout, Bruno Guigas, Pradana Soewondo, Yenny Djuardi, Aprilianto E Wiria, Oleg A Mayboroda, Jeanine J Houwing-Duistermaat, Hengki Tasman, Erliyani Sartono, Maria Yazdanbakhsh, Johannes W A Smit and Taniawati Supali
    Citation: BMC Infectious Diseases 2015 15:133
    Content type: Study protocol Published on:

  7. In Nigeria, reports of the outcomes of prevention of mother to child transmission of HIV (PMTCT) interventions had been limited to the MTCT rates of HIV, with no information on HIV-free survival (HFS) in the H...

    Authors: Emmanuel A Anígilájé, Othniel J Dabit, Ayodotun Olutola, Bem Ageda and Sunday A Aderibigbe
    Citation: BMC Infectious Diseases 2015 15:132
    Content type: Research article Published on:

  8. We have recovered one blaNDM-1-harboring bacterial strain, designated as XM1570, from a sputum sample obtained from a fatal case of pneumonia in China.

    Authors: Peng Li, Chaojie Yang, Jing Xie, Nan Liu, Houzhao Wang, Ling Zhang, Xu Wang, Yong Wang, Shaofu Qiu and Hongbin Song
    Citation: BMC Infectious Diseases 2015 15:131
    Content type: Research article Published on:

  9. Achieving the goal of eliminating mother-to-child HIV transmission (MTCT) necessitates increased access to antiretroviral therapy (ART) for HIV-infected pregnant women. Option B provides ART through pregnancy ...

    Authors: Adam VanDeusen, Elijah Paintsil, Thomas Agyarko-Poku and Elisa F Long
    Citation: BMC Infectious Diseases 2015 15:130
    Content type: Research article Published on:

  10. Antibiotic-associated diarrhea (AAD) is a common adverse effect of antibiotic (AB) treatment. This study aimed to measure the overall prevalence of AAD (including mild to moderate diarrhea) in hospitalized AB ...

    Authors: Monique M Elseviers, Yoleen Van Camp, Sander Nayaert, Khyra Duré, Lieven Annemans, Ann Tanghe and Sebastian Vermeersch
    Citation: BMC Infectious Diseases 2015 15:129
    Content type: Research article Published on:

  11. Antifungal prophylaxis is a promising strategy for reducing invasive fungal infections (IFIs) in allogeneic hematopoietic cell transplant (alloHCT) recipients, but the optimum prophylactic agent is unknown. We...

    Authors: Eric J Bow, David J Vanness, Monica Slavin, Catherine Cordonnier, Oliver A Cornely, David I Marks, Antonio Pagliuca, Carlos Solano, Lael Cragin, Alissa J Shaul, Sonja Sorensen, Richard Chambers, Michal Kantecki, David Weinstein and Haran Schlamm
    Citation: BMC Infectious Diseases 2015 15:128
    Content type: Research article Published on:

  12. Antibiotic resistance is a threat in developing countries (DCs) because of the high burden of bacterial disease and the presence of risk factors for its emergence and spread. This threat is of particular conce...

    Authors: Bich-Tram Huynh, Michael Padget, Benoit Garin, Perlinot Herindrainy, Elsa Kermorvant-Duchemin, Laurence Watier, Didier Guillemot and Elisabeth Delarocque-Astagneau
    Citation: BMC Infectious Diseases 2015 15:127
    Content type: Research article Published on:

  13. The available pharmacokinetic data on anti-tubercular drugs in children raises the concern of suboptimal plasma concentrations attained when doses extrapolated from adult studies are used. Also, there is lack ...

    Authors: Aparna Mukherjee, Thirumurthy Velpandian, Mohit Singla, Kunwar Kanhiya, Sushil K Kabra and Rakesh Lodha
    Citation: BMC Infectious Diseases 2015 15:126
    Content type: Research article Published on:

  14. There is little data regarding the effect of ramping up new screening interventions on their uptake by target populations into routine care services in developing countries. This study aimed to determine patie...

    Authors: Edward Tieru Dassah, Yaw Adu-Sarkodie and Philippe Mayaud
    Citation: BMC Infectious Diseases 2015 15:125
    Content type: Research article Published on:

  15. Acute respiratory infections (ARIs) are common in children and mostly caused by viruses, but the significance of the detection of multiple viruses in ARIs is unclear. This study investigated 14 respiratory vir...

    Authors: Binglin Cui, Dangui Zhang, Hui Pan, Fan Zhang, Jeremy Farrar, Frieda Law, H Rogier van Doorn, Beiyan Wu and William Ba-Thein
    Citation: BMC Infectious Diseases 2015 15:124
    Content type: Research article Published on:

  17. Pseudomonas aeruginosa is an important nosocomial pathogen, commonly causing infections in immunocompromised patients. The aim of this study was to examine the genetic relatedness of metallo-beta-lactamase (MBL) ...

    Authors: Mai Mahmoud Zafer, Mohamed Hamed Al-Agamy, Hadir Ahmed El-Mahallawy, Magdy Aly Amin and Seif El Din Ashour
    Citation: BMC Infectious Diseases 2015 15:122
    Content type: Research article Published on:

  18. Measles cases may cluster in densely populated urban centers in sub-Saharan Africa as susceptible individuals share spatially dependent risk factors and may cluster among human immunodeficiency virus (HIV)-inf...

    Authors: Jessie Pinchoff, James Chipeta, Gibson Chitundu Banda, Samuel Miti, Timothy Shields, Frank Curriero and William John Moss
    Citation: BMC Infectious Diseases 2015 15:121
    Content type: Research article Published on:

  19. Hepatitis B Virus (HBV) disproportionately affects new immigrants from endemic regions such as China. Untreated infections increase health risks for liver diseases including cancer. Yet most of those infected ...

    Authors: Grace X Ma, Guo Yolanda Zhang, Shumenghui Zhai, Xiang Ma, Yin Tan, Steven E Shive and Min Qi Wang
    Citation: BMC Infectious Diseases 2015 15:120
    Content type: Research article Published on:

  20. Successful antiretroviral therapy (ART) has dramatically reduced mortality among HIV-infected children. However, there is growing concern about long-term effects associated to ART. The aim of this study was to...

    Authors: Daniel Blázquez, José Tomás Ramos-Amador, Talía Saínz, María José Mellado, Marta García-Ascaso, María Isabel De José, Pablo Rojo, María Luisa Navarro, María Ángeles Muñoz-Fernández, Jesús Saavedra, Miguel Angel Roa, Santiago Jiménez, José Beceiro, Luis Prieto, Milagros García Hortelano and María Isabel González-Tomé
    Citation: BMC Infectious Diseases 2015 15:119
    Content type: Research article Published on:

  21. Although neonatal infections cause a significant proportion of deaths in the first week of life, little is known about the burden of neonatal disease originating from maternal infection or colonization globall...

    Authors: Grace J Chan, Anne CC Lee, Abdullah H Baqui, Jingwen Tan and Robert E Black
    Citation: BMC Infectious Diseases 2015 15:118
    Content type: Research article Published on:

  22. Tuberculosis (TB) is a global public health concern. It is even more so as its incidence seems to be increasing in South Africa. The aim of this study was to describe and compare the tuberculosis infection con...

    Authors: Ntambwe Malangu and Michah Mngomezulu
    Citation: BMC Infectious Diseases 2015 15:117
    Content type: Research article Published on:

  23. Staphylococcus aureus is one of the most common and lethal causes of bloodstream infection and the incidence is increasing. We carried out a prospective observational study of patients with Staphylococcus aureus ...

    Authors: Julie Paulsen, Arne Mehl, Åsa Askim, Erik Solligård, Bjørn Olav Åsvold and Jan Kristian Damås
    Citation: BMC Infectious Diseases 2015 15:116
    Content type: Research article Published on:

  24. Women in sub-Saharan Africa are vulnerable to acquiring HIV infection and reproductive tract infections. Bacterial vaginosis (BV), a disruption of the vaginal microbiota, has been shown to be strongly associat...

    Authors: Vicky Jespers, Janneke van de Wijgert, Piet Cools, Rita Verhelst, Hans Verstraelen, Sinead Delany-Moretlwe, Mary Mwaura, Gilles F Ndayisaba, Kishor Mandaliya, Joris Menten, Liselotte Hardy and Tania Crucitti
    Citation: BMC Infectious Diseases 2015 15:115
    Content type: Research article Published on:

  25. The use of recombinant viral vectors expressing T. gondii antigens is a safe and efficient approach to induce immune responses against the parasite, as well as a valuable tool for vaccine development. We have pre...

    Authors: Xiu-Zhen Li, Xiao-Hu Wang, Li-Jun Xia, Ya-Biao Weng, Jorge A Hernandez, Li-Qing Tu, Lu-Tao Li, Shou-Jun Li and Zi-Guo Yuan
    Citation: BMC Infectious Diseases 2015 15:114
    Content type: Research article Published on:

  26. Streptococcus pyogenes (group A streptococcus; GAS) is an etiological agent for pharyngitis, pyoderma, and invasive infections in humans. Pharyngitis and pyoderma may lead to serious immune sequelae such as rheum...

    Authors: Mohan G Karmarkar, Gouri P Hule, Ainslie Cameron, Preeti R Mehta, Uday Khopkar, Niwrutti K Hase and Kadaba S Sriprakash
    Citation: BMC Infectious Diseases 2015 15:113
    Content type: Research article Published on:

  27. Ethiopia, a high tuberculosis (TB) burden country, reports one of the highest incidence rates of extra-pulmonary TB dominated by cervical lymphadenitis (TBLN). Infection with Mycobacterium bovis has previously be...

    Authors: Stefan Berg, Esther Schelling, Elena Hailu, Rebuma Firdessa, Balako Gumi, Girume Erenso, Endalamaw Gadisa, Araya Mengistu, Meseret Habtamu, Jemal Hussein, Teklu Kiros, Shiferaw Bekele, Wondale Mekonnen, Yohannes Derese, Jakob Zinsstag, Gobena Ameni…
    Citation: BMC Infectious Diseases 2015 15:112
    Content type: Research article Published on:

  28. Syphilis and HIV infections in pregnancy result in a number of adverse outcomes including neonatal death and vertical transmission. Ethiopia is a country where these infections are highly prevalent. However, d...

    Authors: Mengistu Endris, Tekalign Deressa, Yeshambel Belyhun and Feleke Moges
    Citation: BMC Infectious Diseases 2015 15:111
    Content type: Research article Published on:

  29. Early warning and robust estimation of influenza burden are critical to inform hospital preparedness and operational, treatment, and vaccination policies. Methods to enhance influenza-like illness (ILI) survei...

    Authors: Lydia N Drumright, Simon DW Frost, Alex J Elliot, Mike Catchpole, Richard G Pebody, Mark Atkins, John Harrison, Penny Parker and Alison H Holmes
    Citation: BMC Infectious Diseases 2015 15:110
    Content type: Research article Published on:

  30. Influenza H7N9 has become an endemic pathogen in China where circulating virus is found extensively in wild birds and domestic poultry. Two epidemic waves of Human H7N9 infections have taken place in Eastern a...

    Authors: Amber Farooqui, Alberto J Leon, Linxi Huang, Suwu Wu, Yingmu Cai, Pengzhou Lin, Weihong Chen, Xibin Fang, Tiansheng Zeng, Yisu Liu, Li Zhang, Ting Su, Weibin Chen, Elodie Ghedin, Huachen Zhu, Yi Guan…
    Citation: BMC Infectious Diseases 2015 15:109
    Content type: Research article Published on:

  31. Candida albicans remains as the first cause of nosocomial fungal infections in hospitals worldwide and its susceptibility pattern should be better described in our tertiary care hospitals.

    Authors: Giovanni Rodríguez-Leguizamón, Alessandro Fiori, Katrien Lagrou, María Antonia Gaona, Milciades Ibáñez, Manuel Alfonso Patarroyo, Patrick Van Dijck and Arley Gómez-López
    Citation: BMC Infectious Diseases 2015 15:108
    Content type: Research article Published on:

  32. While enterococci resistant to multiple antimicrobials are spreading in hospitals worldwide, causing urinary tract, wound and bloodstream infections, there is little published data on these infections from Afr...

    Authors: Håvard Aamodt, Stein Christian Mohn, Samuel Maselle, Karim P Manji, Rob Willems, Roland Jureen, Nina Langeland and Bjørn Blomberg
    Citation: BMC Infectious Diseases 2015 15:107
    Content type: Research article Published on:

  33. Literature on the epidemiology of herpes zoster (HZ) in cancer patients is sparse and does not include the elderly. The objectives of this study were to determine the incidence of HZ and related complications ...

    Authors: Mihran A Yenikomshian, Adrienne P Guignard, François Haguinet, Ann S LaCasce, Arthur T Skarin, Alex Trahey, Paul Karner and Mei Sheng Duh
    Citation: BMC Infectious Diseases 2015 15:106
    Content type: Research article Published on:

  34. Predictive models to identify unknown methicillin-resistant Staphylococcus aureus (MRSA) carriage on admission may optimise targeted MRSA screening and efficient use of resources. However, common approaches to mo...

    Authors: Andie S Lee, Angelo Pan, Stephan Harbarth, Andrea Patroni, Annie Chalfine, George L Daikos, Silvia Garilli, José Antonio Martínez and Ben S Cooper
    Citation: BMC Infectious Diseases 2015 15:105
    Content type: Research article Published on:

  35. Cholera, an infectious disease caused by Vibrio cholerae, is a major public health problem and is a particularly burden in developing countries including Nepal. Although the recent worldwide outbreaks of cholera ...

    Authors: Upendra Thapa Shrestha, Nabaraj Adhikari, Rojina Maharjan, Megha R Banjara, Komal R Rijal, Shital R Basnyat and Vishwanath P Agrawal
    Citation: BMC Infectious Diseases 2015 15:104
    Content type: Research article Published on:

  36. Close contacts of patients with tuberculosis (TB) have a substantial risk of developing the disease, particularly during the first year after exposure. Household contact investigation has recently been recomme...

    Authors: Gregory James Fox, Le Phuong Loan, Nguyen Viet Nhung, Nguyen Thi Loi, Dinh Ngoc Sy, Warwick John Britton and Guy Barrington Marks
    Citation: BMC Infectious Diseases 2015 15:103
    Content type: Research article Published on:

  37. Pneumocystis pneumonia (PCP) may develop as a clinical manifestation of nosocomial pneumonia by means of either reactivation of resident P. jirovecii or de novo infection. However, there have been no studies desc...

    Authors: Tark Kim, Sang-Oh Lee, Hyo-Lim Hong, Ju Young Lee, Sung-Han Kim, Sang-Ho Choi, Mi-Na Kim, Yang Soo Kim, Jun Hee Woo and Heungsup Sung
    Citation: BMC Infectious Diseases 2015 15:102
    Content type: Research article Published on:

  38. H1N1 influenza viruses mutate rapidly, rendering vaccines developed in any given year relatively ineffective in subsequent years. Thus it is necessary to generate new vaccines every year, but this is time-cons...

    Authors: Owen Proudfoot, Sandra Esparon, Choon-Kit Tang, Karen Laurie, Ian Barr and Geoffrey Pietersz
    Citation: BMC Infectious Diseases 2015 15:101
    Content type: Research article Published on:

  39. The rate of vertical HIV transmission has decreased in Brazil, but regional inequalities suggest problems in implementing control measures during pregnancy and delivery. The aims of this study were to ascertai...

    Authors: Rosa Maria Soares Madeira Domingues, Celia Landmann Szwarcwald, Paulo Roberto Borges Souza Jr and Maria do Carmo Leal
    Citation: BMC Infectious Diseases 2015 15:100
    Content type: Research article Published on:

  40. Visceral leishmaniasis (VL) or kala-azar cases in seasonal labour migrants from highland areas are addressed to travel history to the Metema–Humera lowlands, northwestern Ethiopia. Factors that affect the inci...

    Authors: Wossenseged Lemma, Habte Tekie, Solomon Yared, Meshesha Balkew, Teshome Gebre-Michael, Alon Warburg and Asrat Hailu
    Citation: BMC Infectious Diseases 2015 15:99
    Content type: Research article Published on:

  41. Tuberculosis (TB) is an important cause of morbidity and mortality worldwide. Toll-like-receptors (TLRs) are important for the recognition of the causative agent Mycobacterium tuberculosis. Negative regulation of...

    Authors: Dana C Blok, Liesbeth M Kager, Arie J Hoogendijk, Ivar O Lede, Wahid Rahman, Rumana Afroz, Paul Bresser, Jaring S van der Zee, Aniruddha Ghose, Caroline E Visser, Menno D de Jong, Abu Shahed Md Zahed, Md Anwar Husain, Khan Mashrequl Alam, Pravat Chandra Barua, Mahtabuddin Hassan…
    Citation: BMC Infectious Diseases 2015 15:98
    Content type: Research article Published on:

  42. The present study aims to investigate the potential mechanism of linezolid-resistant Staphylococcus capitis (LRSC) isolates collected from our hospital.

    Authors: Wanqing Zhou, Dongmei Niu, Xiaoli Cao, Mingzhe Ning, Zhifeng Zhang, Han Shen and Kui Zhang
    Citation: BMC Infectious Diseases 2015 15:97
    Content type: Research article Published on:

  43. Visceral leishmaniasis is a disease caused by the protozoan Leishmania sp. and is transmitted by Lutzomyia longipalpis (sand fly). In renal transplant recipients, visceral leishmaniasis causes severe damage to th...

    Authors: Avelar Alves de Silva, Álvaro Pacheco E Silva Filho, Ricardio de Castro Cinta Sesso, Ronaldo de Matos Esmeraldo, Cláudia Maria Costa de Oliveira, Paula Frassinetti Castelo Branco Camurca Fernandes, Rodrigo Alves de Oliveira, Leila Silveira Veira de Silva, Valencio Pereira de Carvalho, Carlos Henrique Nery Costa, Jesusmar Ximenes Andrade, Diana Marisa Barros da Silva and Roosevelt Valente Chaves
    Citation: BMC Infectious Diseases 2015 15:96
    Content type: Research article Published on:

  44. Reducing acute respiratory infection burden in children in Africa remains a major priority and challenge. We analyzed data from population-based infectious disease surveillance for severe acute respiratory ill...

    Authors: Robert F Breiman, Leonard Cosmas, M Kariuki Njenga, John Williamson, Joshua A Mott, Mark A Katz, Dean D Erdman, Eileen Schneider, M Steven Oberste, John C Neatherlin, Henry Njuguna, Daniel M Ondari, Kennedy Odero, George O Okoth, Beatrice Olack, Newton Wamola…
    Citation: BMC Infectious Diseases 2015 15:95
    Content type: Research article Published on:

  45. Sporotrichosis is a cutaneous and subcutaneous fungal disease of humans and other mammals, known to be caused by the Sporothrix schenckii species complex, which comprises four species of clinical importance: S. b...

    Authors: Emma Camacho, Isabel León-Navarro, Sabrina Rodríguez-Brito, Mireya Mendoza and Gustavo A Niño-Vega
    Citation: BMC Infectious Diseases 2015 15:94
    Content type: Research article Published on:

  46. A cost-effective, accurate and rapid simultaneous multiplex assay is required for testing and diagnoses of conventional and emerging viruses in clinical virology laboratories. We developed and optimized a dual...

    Authors: Xuezheng Ma, Huanzhou Xu, Lei Shi, Pengfei Yang, Liping Zhang, Xiaohong Sun, Wei Zhen and Kongxin Hu
    Citation: BMC Infectious Diseases 2015 15:93
    Content type: Research article Published on:

  47. Although rotavirus vaccines have been licensed in Spain for over 8 years, they are not funded by its public health systems. The analysis of their effectiveness in the Valencia Region could better inform decisi...

    Authors: Silvia Pérez-Vilar, Javier Díez-Domingo, Mónica López-Lacort, Sergio Martínez-Úbeda and Miguel A Martinez-Beneito
    Citation: BMC Infectious Diseases 2015 15:92
    Content type: Research article Published on:

  48. Clostridium difficile infection (CDI) is a leading cause of diarrhoea in health care settings with symptoms ranging from mild and self-limiting to life threatening. SMT19969 is a novel, non-absorbable antibiotic ...

    Authors: Richard Vickers, Neil Robinson, Emma Best, Roger Echols, Glenn Tillotson and Mark Wilcox
    Citation: BMC Infectious Diseases 2015 15:91
    Content type: Research article Published on:

  49. Dose-response assessment is one step in quantitative microbial risk assessment (QMRA). Four infectious microbes capable of causing respiratory diseases important to public health, and for which dose-response f...

    Authors: Rachael M Jones and Yu-Min Su
    Citation: BMC Infectious Diseases 2015 15:90
    Content type: Research article Published on:

  50. Better knowledge of distribution of respiratory viruses (RVs) in adolescents and adults with community-acquired pneumonia (CAP) is needed.

    Authors: Jiu-Xin Qu, Li Gu, Zeng-Hui Pu, Xiao-Min Yu, Ying-Mei Liu, Ran Li, Yi-Min Wang, Bin Cao and Chen Wang
    Citation: BMC Infectious Diseases 2015 15:89
    Content type: Research article Published on:

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