Articles

Disseminated Talaromyces marneffei infection presenting as multiple intestinal perforations and diffuse hepatic granulomatous inflammation in an infant with STAT3 mutation: a case report

Talaromyces marneffei is a highly pathogenic fungus that can cause life-threatening fatal systemic mycosis. Disseminated Talaromycosis marneffei affects multiple organs, including the lungs, skin, and reticuloend...

Authors: Mianluan Pan, Ye Qiu, Wen Zeng, Shudan Tang, Xuan Wei and Jianquan Zhang

Productivity costs from a dengue episode in Asia: a systematic literature review

Dengue is a mosquito-borne viral infection which has been estimated to cause a global economic burden of US$8.9 billion per year. 40% of this estimate was due to what are known as productivity costs (the costs...

Authors: Trinh Manh Hung, Donald S. Shepard, Alison A. Bettis, Huyen Anh Nguyen, Angela McBride, Hannah E. Clapham and Hugo C. Turner

Serosurvey of Treponema pallidum infection among children with skin ulcers in the Tarangire-Manyara ecosystem, northern Tanzania

The first yaws eradication campaign reduced the prevalence of yaws by 95%. In recent years, however, yaws has reemerged and is currently subject to a second, ongoing eradication campaign. Yet, the epidemiologi...

Authors: Clara K. C. Lubinza, Simone Lueert, Luisa K. Hallmaier-Wacker, Esther Ngadaya, Idrissa S. Chuma, Rudovick R. Kazwala, Sayoki G. M. Mfinanga, Klaus Failing, Christian Roos and Sascha Knauf

The clinical characteristics and risk factors for necrotizing pneumonia caused by Mycoplasma pneumoniae in children

The incidence of necrotizing pneumonia (NP) caused by Mycoplasma pneumoniae (MP) is increasing. We analyzed the clinical characteristics and the risk factors for NP caused by MP.

Authors: Baoying Zheng, Jing Zhao and Ling Cao

Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran

Fluoroquinolones are broad-spectrum antibiotics that are recommended, and increasingly important, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Resistance to fluoroquinolones is caused by mut...

Authors: Mahdieh Sayadi, Hosna Zare, Saeed Amel Jamedar, Seyed Isaac Hashemy, Zahra Meshkat, Saman Soleimanpour, Sven Hoffner and Kiarash Ghazvini

Corynebacterium striatum meningitis combined with suspected brain and lung abscesses: a case report and review

Intracranial infections with Corynebacterium striatum (C. striatum) have been described sporadically in the literature over the last two decades. However, C. striatum meningitis combined with multiple abscesses h...

Authors: Ming-Jie Zhang, Xiao-Jie Cao, Jin Fan, Ze-Gang Yin and Ke Yu

Neurogenic pulmonary edema following febrile status epilepticus in a 22-month-old infant with multiple respiratory virus co-detection: a case report

Neurogenic pulmonary edema is a rare but serious complication of febrile status epilepticus in children. Comprehensive screening for viral pathogens is seldomly performed in the work-up of febrile children.

Authors: Yoshie Takagi, Takeaki Imamura, Shota Endo, Kenta Hayashi, Satoka Akiyama, Yoji Ikuta, Takahiro Kawaguchi, Tomoko Sumita, Tatsuo Katori, Masanori Hashino, Shinji Saito, Takato Odagiri, Kunihiro Oba, Makoto Kuroda and Tsutomu Kageyama

Comparison of clinical features of acute lower respiratory tract infections in infants with RSV/HRV infection, and incidences of subsequent wheezing or asthma in childhood

To compare the clinical characteristics of acute lower respiratory tract infections (ALRTIs) caused by respiratory syncytial virus (RSV) and human rhinovirus (HRV) and to explore the relationship between the d...

Authors: Qin Ding, Lili Xu, Yun Zhu, Baoping Xu, Xiangpeng Chen, Yali Duan, Zhengde Xie and Kunling Shen

Clients’ perceptions of barriers and facilitators to implementing hepatitis C virus care in homeless shelters

Hepatitis C virus (HCV) is highly prevalent among homeless persons, yet barriers continue to impede HCV testing and treatment in this population. We studied the experiences of homeless individuals related to a...

Authors: Carmen L. Masson, J. Konadu Fokuo, August Anderson, Jesse Powell, Barry Zevin, Dylan Bush and Mandana Khalili

Prognostic accuracy of SIRS criteria and qSOFA score for in-hospital mortality among influenza patients in the emergency department

The seasonal influenza epidemic is an important public health issue worldwide. Early predictive identification of patients with potentially worse outcome is important in the emergency department (ED). Similarl...

Authors: Sheng-En Chu, Chen-June Seak, Tse-Hsuan Su, Chung-Hsien Chaou, Hsiao-Jung Tseng and Chih-Huang Li

Epidemiology and risk factors of Staphylococcus aureus CC398 bone and joint infections

A particular ability of the Staphylococcus aureus clonal complex 398 (CC398) to cause bone and joint infections (BJI) remains questionable, since some studies have described high prevalence of MSSA CC398 in prost...

Authors: Kevin Bouiller, Didier Hocquet, Marlene Sauget, Xavier Bertrand and Catherine Chirouze

Neurocognitive impairment in treatment-experienced adults living with HIV attending primary care clinics in Zimbabwe

HIV affects the central nervous system resulting in HIV associated neurocognitive impairment (NCI) in approximately 50% of people living with HIV. It typically affects memory, learning, working memory, fine mo...

Authors: Primrose Nyamayaro, Hetta Gouse, James Hakim, Reuben N. Robbins and Dixon Chibanda

Human immunodeficiency virus positive status disclosure to a sexual partner and its determinant factors in Ethiopia: a systematic review and meta-analysis

Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to raise awar...

Authors: Fikadu Yehualashet, Eleni Tegegne, Mekbib Tessema and Mulualem Endeshaw

Cryptococcus meningitis mimicking cerebral septic emboli, a case report series demonstrating injection drug use as a risk factor for development of disseminated disease

Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if...

Authors: Christopher Polk, Jacqueline Meredith, Alyssa Kuprenas and Michael Leonard

Prevalence and associated factors of scabies in Ethiopia: systematic review and Meta-analysis

Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high an...

Authors: Abebaw Gedef Azene, Abiba Mihret Aragaw and Gizachew Tadesse Wassie

Intestinal parasitosis, anaemia and risk factors among pre-school children in Tigray region, northern Ethiopia

Intestinal parasitic infections (IPIs) and anaemia are major health problems. This study assessed the prevalence of intestinal parasitic infections, anaemia and associated factors among pre-school children in ...

Authors: Araya Gebreyesus Wasihun, Mekonen Teferi, Letemichal Negash, Javier Marugán, Dejen Yemane, Kevin G. McGuigan, Ronan M. Conroy, Haftu Temesgen Abebe and Tsehaye Asmelash Dejene

A rare case of brain abscess caused by Actinomyces meyeri

Brain abscesses are the rare and most severe form of actinomycosis, which usually manifests as abscesses of the occipital or parietal lobe due to direct expansion from an adjacent area, the oral cavity. In the...

Authors: Ranjit Sah, Gaurav Nepal, Sanjit Sah, Sonam Singla, Priti Upadhyay, Ali A. Rabaan, Kuldeep Dhama, Alfonso J. Rodriguez-Morales and Rabindra Ghimire

Case report: nosocomial fungemia caused by Candida diddensiae

Candida diddensiae, a yeast found in olive oil, is considered non-pathogenic to humans. Here, we describe the first case of fungemia caused by C. diddensiae in a hospitalized patient with underlying diseases.

Authors: Seong Eun Kim, Sook In Jung, Kyung-Hwa Park, Yong Jun Choi, Eun Jeong Won and Jong Hee Shin

Efficacy of a single dose versus a multiple dose regimen of Mebendazole against hookworm infections among school children: a randomized open-label trial

Despite the existence of a population-based control program using single dose albendazole or mebendazole as a preventive chemotherapy, hookworm transmission remains high. It causes a negative impact on the gro...

Authors: Tegegne Eshetu, Mulugeta Aemero and Ayalew Jejaw Zeleke

Molecular epidemiology and socio-demographic risk factors of sexually transmitted infections among women in Lebanon

Sexually transmitted infections (STIs) cause a major public health problem that affect both men and women in developing and developed countries. The aim of the study was to estimate the prevalence of 11 STIs a...

Authors: Jessica Hanna, Ruba Yassine, Rana El-Bikai, Martin D. Curran, Mathilde Azar, Joumana Yeretzian, Rana Skaf, Claude Afif, Toufic Saber, Saadeddine Itani, Manal Hubeish, Tamima El Jisr, Fadia Hamzeh and Mira El Chaar

The effect of oral care intervention on pneumonia hospitalization, Staphylococcus aureus distribution, and salivary bacterial concentration in Taiwan nursing home residents: a pilot study

Elevated Staphylococcus aureus and oral bacterial concentrations are known to correlate with pneumonia hospitalization in nursing home residents. However, the effects of a professional oral care intervention on t...

Authors: Tien-Cheng Chiang, Ming-Shyan Huang, Po-Liang Lu, Shun-Te Huang and Ying-Chu Lin

Resurgence risk for malaria, and the characterization of a recent outbreak in an Amazonian border area between French Guiana and Brazil

In 2017, inhabitants along the border between French Guiana and Brazil were affected by a malaria outbreak primarily due to Plasmodium vivax (Pv). While malaria cases have steadily declined between 2005 and 2016 ...

Authors: Emilie Mosnier, Isabelle Dusfour, Guillaume Lacour, Raphael Saldanha, Amandine Guidez, Margarete S. Gomes, Alice Sanna, Yanouk Epelboin, Johana Restrepo, Damien Davy, Magalie Demar, Félix Djossou, Maylis Douine, Vanessa Ardillon, Mathieu Nacher, Lise Musset…

Diagnostic performance of APRI and FIB-4 for confirming cirrhosis in Indonesian HIV/HCV co-infected patients

After successful of antiretroviral therapy, highly effective direct acting antiviral (DAA) make HCV elimination reasonable in HIV/HCV co-infected patients. However, in achieving this target, there are still ba...

Authors: Evy Yunihastuti, Bramantya Wicaksana, Andrian Wiraguna, Ainum Jhariah Hidayah, Fhadilla Amelia, Veritea Natali, Alvina Widhani, Andri Sanityoso Sulaiman and Juferdy Kurniawan

Zika virus in southeastern Senegal: survival of the vectors and the virus during the dry season

Zika virus (ZIKV, genus Flavivirus, family Flaviviridae) is transmitted mainly by Aedes mosquitoes. This virus has become an emerging concern of global public health with recent epidemics associated to neurologic...

Authors: Babacar Diouf, Alioune Gaye, Cheikh Tidiane Diagne, Mawlouth Diallo and Diawo Diallo

Precision diagnosis and therapy of a case of brain abscesses associated with asymptomatic pulmonary arteriovenous fistulas

Brain abscesses, a severe infectious disease of the CNS, are usually caused by a variety of different pathogens, which include Streptococcus intermedius (S. intermedius). Pulmonary arteriovenous fistulas (PAVFs),...

Authors: Lu-Yao Gao, Guang-Run Xu and Ting-Jun Dai

Live poultry market closure and avian influenza A (H7N9) infection in cities of China, 2013–2017: an ecological study

Previous studies have proven that the closure of live poultry markets (LPMs) was an effective intervention to reduce human risk of avian influenza A (H7N9) infection, but evidence is limited on the impact of s...

Authors: Ying Chen, Jian Cheng, Zhiwei Xu, Wenbiao Hu and Jiahai Lu

Hepatitis E virus infection in pregnant women, Argentina

Hepatitis E virus (HEV) infection is an important cause of acute hepatitis worldwide. In pregnant women, HEV can cause more severe symptoms, with high rates of fatal hepatic failure in endemic countries. Howev...

Authors: Gabriela Tissera, María Cecilia Lardizabal, Sofía Belén Torres, Anabella Clara Fantilli, Maribel G. Martínez Wassaf, Fernando Venezuela, Raúl Capra, Domingo C. Balderramo, Claudia Travella, Viviana E. Ré and María Belén Pisano

Early diagnosis and appropriate respiratory support for Mycoplasma pneumoniae pneumonia associated acute respiratory distress syndrome in young and adult patients: a case series from two centers

Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community acquired pneumonia (CAP). Establishing an early diagnosis of M. pneumoniae pneumonia in patients with acute respiratory distress...

Authors: Lin Ding, Yu Zhao, Xuyan Li, Rui Wang, Ying Li, Xiao Tang, Bing Sun and Hangyong He

Identification of Kosakonia cowanii as a rare cause of acute cholecystitis: case report and review of the literature

Kosakonia cowanii, formerly known as Enterobacter cowanii, is a Gram-negative bacillus belonging to the order Enterobacterales. The species is usually recognized as a plant pathogen and has only anecdotally been ...

Authors: Benjamin Berinson, Eugen Bellon, Martin Christner, Anna Both, Martin Aepfelbacher and Holger Rohde

Successful bedaquiline-containing antimycobacterial treatment in post-traumatic skin and soft-tissue infection by Mycobacterium fortuitum complex: a case report

Mycobacterium fortuitum complex is a group of rapidly growing nontuberculous mycobacteria (NTM) associated with skin and soft-tissue infections after surgery or trauma. Treatment of NTM is challenging, due to res...

Authors: Johanna Erber, Simon Weidlich, Tristan Tschaikowsky, Kathrin Rothe, Roland M. Schmid, Jochen Schneider and Christoph D. Spinner

Underdiagnoses of Rickettsia in patients hospitalized with acute fever in Indonesia: observational study results

Reports of human rickettsial infection in Indonesia are limited. This study sought to characterize the epidemiology of human rickettsioses amongst patients hospitalized with fever at 8 tertiary hospitals in In...

Authors: Dewi Lokida, Usman Hadi, Chuen-Yen Lau, Herman Kosasih, C. Jason Liang, Musofa Rusli, Pratiwi Sudarmono, Nurhayati Lukman, Kanti Laras, Rizka Humardewayantie Asdie, Dewi Murniati, I Made Susila Utama, Risna Halim Mubin, Muhammad Karyana, Muhammad Hussein Gasem and Bachti Alisjahbana

Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports

Plasmodium vivax rarely develops severe complications when compared to severe falciparum malaria. However, severe vivax malaria also needs urgent, intensive care and treatment as severe falciparum malaria. This s...

Authors: Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez and Frederick Ramirez Masangkay

A retrospective study on Xpert MTB/RIF for detection of tuberculosis in a teaching hospital in China

The Xpert MTB/RIF assay is an automated molecular test that is designed to simultaneously detect Mycobacterium tuberculosis (MTB) complex and rifampin resistance. However, there are relatively few studies on this...

Authors: Shuguang Li, Liyan Lin, Feifei Zhang, Chunjiang Zhao, Han Meng and Hui Wang

Meningococcaemia causing necrotizing cellulitis associated with acquired complement deficiency after gastric bypass surgery: a case report

Neisseria meningitidis has rarely been described as an agent of necrotic soft tissue infection.

Authors: Zoe Pletschette, Elodie De Groote, Wesley Mattheus, Charlotte Waxweiler, Jacques Creteur and David Grimaldi

A case of acanthosis nigricans in a HIV-infected patient

To date, very little information is available concerning the relationship between acanthosis nigricans (AN) and infection with human immunodeficiency virus type 1 (HIV-1).

Authors: Alessandra Iacovelli, Ivano Mezzaroma, Marcello Di Paolo, Giuseppe Soda, Ludovica De Vincentiis and Paolo Palange

Adherence to guidelines across different specialties to prevent infections in patients undergoing immunosuppressive therapies

Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of developing opportunistic infections or re-activation of lat...

Authors: David R. Chadwick, Laila Sayeed, Matthew Rose, Emily Budd, Mo Mohammed, Sarah Harrison, Jaskiran Azad and Jamie Maddox

Carriage rate of Neisseria meningitidis, antibiotic susceptibility pattern and associated risk factors among primary school children in Gondar town, Northwest Ethiopia

Globally, in 2012, about 1.2 million estimated cases were reported with ~ 135,000 deaths annually. In Ethiopia, specifically in our study area, limited information is found on the oropharyngeal carriage, antim...

Authors: Zelalem Tefera, Feleke Mekonnen, Moges Tiruneh and Teshome Belachew

Abstracts from the International Science Symposium on HIV and Infectious Diseases (ISSHID 2019): Infectious diseases

Authors:

Unusual subdural empyema in a homeless patient diagnosed by molecular approach: a case report

We report a case of subdural empyema in a homeless patient caused by Bartonella quintana. B. quintana is a facultative intracellular bacteria for which bacterial growth is fastidious. The molecular biology approa...

Authors: Cécile Brin, Wladimir Sougakoff, Franck Bielle, Samya Abi Jaoude, Isabelle Bonnet, Elie Haddad, Eric Caumes and Stéphane Jauréguiberry

Performance of malaria microscopy external quality assessment and networking among health facilities in west Amhara region, Ethiopia

Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory perso...

Authors: Banchamlak Tegegne, Kefale Ejigu, Getaneh Alemu, Yeshimebet Fetene, Kindye Endaylalu and Mulatu Melese

Spontaneous community-acquired PVL-producing Staphylococcus aureus mediastinitis in an immunocompetent adult – a case report

Mediastinitis caused by hematogenous spread of an infection is rare. We report the first known case of community-acquired mediastinitis from hematogenous origin in an immunocompetent adult. This rare invasive ...

Authors: Josselin Brisset, Thomas Daix, Jérémy Tricard, Bruno Evrard, Philippe Vignon, Olivier Barraud and Bruno François

Pathogen analysis of pertussis-like syndrome in children

The aim of the study was to identify the pathogens, in addition to bordetella pertussis (B. pertussis), which cause pertussis-like syndrome in children and to compare clinical presentation between those with B. p...

Authors: Wenjing Gu, Kun Wang, Xinxing Zhang, Chuangli Hao, Yanhong Lu, Min Wu, Sainan Chen, Yanyu He, Jun Xu, Xuejun Shao and Yuqing Wang

Solutions to improve the latent tuberculosis Cascade of Care in Ghana: a longitudinal impact assessment

Loss of patients in the latent tuberculosis infection (LTBI) cascade of care is a major barrier to LTBI management. We evaluated the impact and acceptability of local solutions implemented to strengthen LTBI m...

Authors: Leila Barss, Joseph Obeng, Federica Fregonese, Olivia Oxlade, Benjamin Adomako, Anthony Opoku Afriyie, Erica Dapaah Frimpong, Nicholas Winters, Chantal Valiquette and Dick Menzies

Lung abscess secondary to lung cancer with Eikenella corrodens and Streptococcus anginosus: a case report

Eikenella corrodens and Streptococcus anginosus, which are primary colonization bacteria of the normal flora of the oropharynx, are infrequent bacteria, especially the former. Here, we report a case of lung absce...

Authors: Leihao Hu, Jietao Lin, Jing Li, Yang Cao and Lizhu Lin

Molecular prevalence of intestinal parasites infections in children with diarrhea in Franceville, Southeast of Gabon

Pediatric diarrhea caused by a range of pathogens, including intestinal parasites, is one of main causes of death among children under 5 years of age. The distribution of these parasitic infections overlaps in...

Authors: Sandrine Lydie Oyegue-Liabagui, Nal Kennedy Ndjangangoye, Lady Charlene Kouna, Gwladys Mirlande Lekolo, Franck Mounioko, Sylvie Kwedi Nolna and Jean Bernard Lekana-Douki

Ultrasound in managing extrapulmonary tuberculosis: a randomized controlled two-center study

Patients with clinically suspected tuberculosis are often treated empirically, as diagnosis - especially of extrapulmonary tuberculosis - remains challenging. This leads to an overtreatment of tuberculosis and...

Authors: Robert Ndege, Omary Ngome, Farida Bani, Yvan Temba, Herieth Wilson, Fiona Vanobberghen, Jerry Hella, Winfrid Gingo, Mohamed Sasamalo, Dorcas Mnzava, Namvua Kimera, Helen Hiza, John Wigayi, Herry Mapesi, Irene B. Kato, Francis Mhimbira…

Blackfly fever and dermatitis caused by Simulium kiritshenkoi: a human case report in Iran

Besides the considerable role of blackflies to the transmission of many disease agents, these flies considered as annoying biting pests of wildlife, livestock, poultry, and humans. There are few literature rep...

Authors: Farbod Tabatabaei, Sahar Azarmi, Mohammad Javad Abbaszadeh Afshar, Hamed Yarizadeh and Sina Mohtasebi

Epidemiological analysis of the Kaohsiung city strategy for dengue fever quarantine and epidemic prevention

Dengue is endemic in over 100 countries and is an important public health problem worldwide. Dengue fever is not endemic in Taiwan; the importation of dengue viruses from neighboring countries via close commer...

Authors: Chao-Ying Pan, Wei-Liang Liu, Matthew-P. Su, Te-Pin Chang, Hui-Pin Ho, Pei-Yun Shu, Joh-Jong Huang, Li-Jen Lin and Chun-Hong Chen

Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus

To analyze and discuss the transmission route of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus (SFTSV).

Authors: Lingling Mao, Baocheng Deng, Yuhong Liang, Yun Liu, Zijiang Wang, Jie Zhang, Wei Wu, Lei Yu and Wenqing Yao

Prevalence of sexually transmitted infections among foreigners living in Guangzhou, China: a cross-sectional study (2010–2017)

The prevalence of HIV/HCV/HBV/ Treponema pallidum is an essential health issue in China. However, there are few studies focused on foreigners living in China. This study aimed to assess the prevalence and socio-d...

Authors: Benard Chimungu, Muqing Fu, Jian Wu, Jiali Wu, Liping Huang, Yingchun Dai, Shixing Tang, Jianming Zhang and Chengsong Wan