World Health Organization: Department of Communicable diseases surveillance and response. Hepatitis B. WHO Fact Sheets. Accessed: September 24, 2004, [http://www.who.int]
Stoop JN, Molen van der RG, Kuipers EJ, Kusters JG, Janssen HL: Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Virology. 2007, 361: 141-148. 10.1016/j.virol.2006.11.018.
Article
CAS
PubMed
Google Scholar
Michalak TI, Hodgson PD, Churchill ND: Posttranscriptional inhibition of class I major histocompatibility complex presentation on hepatocytes and lymphoid cells in chronic woodchuck hepatitis virus infection. J Virol. 2000, 74: 4483-4494. 10.1128/JVI.74.10.4483-4494.2000.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tulek N, Saglam SK, Saglam M, Turkyilmaz R, Yildiz M: Soluble interleukin-2 receptor and interleukin-10 levels in patients with chronic hepatitis B infection. Hepatogastroenterology. 2000, 47: 828-831.
CAS
PubMed
Google Scholar
Khettry U, Anand N, Gordon FD, Jenkins RL, Tahan SR, Loda M, Lewis WD: Recurrent hepatitis B, hepatitis C, and combined hepatitis B and C in liver allografts: a comparative pathological study. Hum Pathol. 2000, 31: 101-108. 10.1016/S0046-8177(00)80205-1.
Article
CAS
PubMed
Google Scholar
Baumert TF, Thimme R, von Weizsäcker F: Pathogenesis of hepatitis B virus infection. World J Gastroenterol. 2007, 13: 82-90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bertoletti A, Gehring AJ: The immune response during hepatitis B virus infection. J Gen Virol. 2006, 87: 1439-1449. 10.1099/vir.0.81920-0.
Article
CAS
PubMed
Google Scholar
Liu DX: A new hypothesis of pathogenetic mechanism of viral hepatitis B and C. Med Hypotheses. 2001, 56: 405-408. 10.1054/mehy.2000.1157.
Article
CAS
PubMed
Google Scholar
Stoop JN, Molen van der RG, Baan CC, Laan van der LJ, Kuipers EJ, Kusters JG, Janssen HL: Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology. 2005, 41: 771-778. 10.1002/hep.20649.
Article
CAS
PubMed
Google Scholar
Franzese O, Kennedy PT, Gehring AJ, Gotto J, Williams R, Maini MK, Bertoletti A: Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection. J Virol. 2005, 79: 3322-3328. 10.1128/JVI.79.6.3322-3328.2005.
Article
CAS
PubMed
PubMed Central
Google Scholar
Boni C, Bertoletti A, Penna A, Cavalli A, Pilli M, Urbani S, Scognamiglio P, Boehme R, Panebianco R, Fiaccadori F, Ferrari C: Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B. J Clin Invest. 1998, 102: 968-975. 10.1172/JCI3731.
Article
CAS
PubMed
PubMed Central
Google Scholar
Boni C, Penna A, Ogg GS, Bertoletti A, Pilli M, Cavallo C, Cavalli A, Urbani S, Boehme R, Panebianco R, Fiaccadori F, Ferrari C: Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy. Hepatology. 2001, 33: 963-971. 10.1053/jhep.2001.23045.
Article
CAS
PubMed
Google Scholar
Boni C, Penna A, Bertoletti A, Lamonaca V, Rapti I, Missale G, Pilli M, Urbani S, Cavalli A, Cerioni S, Panebianco R, Jenkins J, Ferrari C: Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B. J Hepatol. 2003, 39: 595-605. 10.1016/S0168-8278(03)00292-7.
Article
CAS
PubMed
Google Scholar
Dienstag JL, Wei LJ, Xu D, Kreter B: Cross-study analysis of the relative efficacies of oral antiviral therapies for chronic hepatitis B infection in nucleoside-naive patients. Clin Drug Investig. 2007, 27: 35-49. 10.2165/00044011-200727010-00003.
Article
CAS
PubMed
Google Scholar
Tillmann HL: Antiviral therapy and resistance with hepatitis B virus infection. World J Gastroenterol. 2007, 13: 125-140.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rivkin A: A review of entecavir in the treatment of chronic hepatitis B infection. Curr Med Res Opin. 2005, 21: 1845-56. 10.1185/030079905X65268.
Article
CAS
PubMed
Google Scholar
Gish RG, Perrillo RP, Jacobson IM: Customizing the management of chronic hepatitis B virus infection. Semin Liver Dis. 2007, 27: 9-17. 10.1055/s-2007-984695.
Article
CAS
PubMed
Google Scholar
Keeffe EB, Marcellin P: New and emerging treatment of chronic hepatitis B. Clin Gastroenterol Hepatol. 2007, 5: 285-294. 10.1016/j.cgh.2006.09.036.
Article
CAS
PubMed
Google Scholar
Chang TT, Gish R, de Man R, Gadano A, Sollano J, Chao YC, Lok AS, Han KH, Goodman Z, Zhu J, Apelian D: A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med. 2006, 354: 1001-1010. 10.1056/NEJMoa051285.
Article
CAS
PubMed
Google Scholar
Lai CL, Shouval D, Lok AS, Chang TT, Cheinquer H, Goodman Z, DeHertogh D, Wilber R, Zinki RC, Cross A, Colonno R, Fernandes L: Entecavir versus lamivudine for HBeAg-negative chronic hepatitis B. N Engl J Med. 2006, 354: 1011-1020. 10.1056/NEJMoa051287.
Article
CAS
PubMed
Google Scholar
Yao G, Chen CJ, Lu W, Ren H, Tan D, Wang Y, Xu D, Jiang M, Liu J, Xu D, MacDonald L: Entecavir is superior to lamivudine for the treatment of chronic hepatitis B (CHB): results of a phase 3 Chinese study (ETV-023) in nucleoside-naïve patients. J Hepatol. 2006, 44: S193-
Google Scholar
Sherman M, Yurdaydin C, Sollano J, Silva M, Liaw YF, Cianciara J, Boron-Kaczmarska A, Martin P, Goodman Z, Colonno R, Cross A, Denisky G, Kreter G, Hindes R, AI463026 BEHoLD Study Group: Entecavir for Treatment of Lamivudine-Refractory, HBeAg-Positive Chronic Hepatitis B. Gasgtroenterol. 2006, 130: 2039-2049. 10.1053/j.gastro.2006.04.007.
Article
CAS
Google Scholar
Lok AS, McMahon BJ: Chronic hepatitis B. Hepatology. 2007, 45: 507-539. 10.1002/hep.21513.
Article
CAS
PubMed
Google Scholar
R Development Core Team: R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, Assessed: October 3, 2007, [http://www.R-project.org]
Chongsuvivatwong V: The epicalc package. Assessed: November 1, 2007., [http://www.cran.R-project.org]
Leung N, Peng C-Y, Sollano J, Lesmana L, Yuen M-F, Jeffers L, Han H-W, Sherman M, Zhu J, Mencarini K, Colonno R, Cross A, Wilber R, Lopez-Talavera J-C: Entecavir results in higher HBV DNA reduction vs adefovir in chronically infected HBeAg(+) antiviral-naïve adults: 24 wk results (E.A.R.L.Y. study). Hepatology. 2006, 44: 554A-
Google Scholar
Gish RG, Lok AS, Chang TT, De Man RA, Gadano A, Sollano J, Han KH, Chao YC, Lee SD, Harris JY, Colonno R, Brett-Smith H: Entecavir Therapy for up to 96 Weeks in Patients With HBeAg-Positive Chronic Hepatitis B. Gastroenterology. 2007, 133: 1437-1444. 10.1053/j.gastro.2007.08.025.
Article
CAS
PubMed
Google Scholar
Stoop JN, Molen van der RG, Kuipers EJ, Kusters JG, Janssen HL: Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Virology. 2007, 361: 141-148. 10.1016/j.virol.2006.11.018.
Article
CAS
PubMed
Google Scholar
Lau GK, Cooksley H, Ribeiro RM, Powers KA, Shudo E, Bowden S, Hui CK, Anderson J, Sorbel J, Mondou E, Rousseau F, Lewin S, Perelson AS, Locornini S, Naoumov NV: Impact of early viral kinetics on T-cell reactivity during antiviral therapy in chronic hepatitis B. Antivir Ther. 2007, 12: 705-718.
CAS
PubMed
Google Scholar
Kondo Y, Asabe S, Kobayashi K, Shiina M, Niitsuma H, Ueno Y, Kobayashi T, Shimosegawa T: Recovery of functional cytotoxic T lymphocytes during lamivudine therapy by acquiring multi-specificity. J Med Virol. 2004, 74: 425-433. 10.1002/jmv.20194.
Article
CAS
PubMed
Google Scholar
Mizukoshi E, Sidney J, Livingston B, Ghany M, Hoofnagle JH, Sette A, Rehermann B: Cellular immune responses to the hepatitis B virus polymerase. J Immunol. 2004, 173: 5863-5871.
Article
CAS
PubMed
Google Scholar