BMC Infectious Diseases

Table 3 Multivariate multilevel regression model predicting peripheral blood T lymphocyte subpopulations from relevant parameters (n = 55)*

From: Impact of viral replication inhibition by entecavir on peripheral T lymphocyte subpopulations in chronic hepatitis B patients

	CD3⁺T Lymphocyte			CD4⁺T Lymphocyte			CD8⁺T Lymphocyte
Variables	β	SE	P value	β	SE	P value	β	SE	P value
Fixed effects
Intercept	44.50	1.31	--	28.09	0.88	--	39.85	1.09	--
Weeks **	0.21	0.01	<0.0001	0.18	0.01	<0.0001	-0.23	0.01	<0.0001
Period (4–48 week vs < 4 week)	0.99	0.75	0.19	1.92	0.72	<0.01	-2.07	0.86	0.02
HBV DNA (Log, copies/mL) **	0.07	0.09	0.47	-0.01	0.09	0.92	0.09	0.11	0.41
HBV DNA (Log, copies/mL) × period	-0.29	0.14	0.03	-0.48	0.13	<0.001	0.42	0.16	<0.01
Random effects:	Intercept = 8.49			Intercept = 4.71			Intercept = 6.02
	SD = 1.73			SD = 1.66			SD = 1.97

*β = Coefficients from the model, SE = Standard Error, SD = Standard Deviation. **Continuous variable.

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