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Table 1 Characteristics of the CHB patients at entry to the study*

From: Impact of viral replication inhibition by entecavir on peripheral T lymphocyte subpopulations in chronic hepatitis B patients

Characteristics All patients
(n = 55)
Sex (male/female) 42/13
Mean age (in years) 30.9 ± 8.5
Duration of infection (years) 13.8 ± 8.7
Serum ALT level (IU/L) 251.4 ± 66.1
Serum AST level (IU/L) 195.7 ± 81.6
Serum total bilirubin level (μmol/mL) 26.7 ± 18.1
Serum HBV DNA (copies/mL)  
   > 1.0 × 105 ~ 1.0 × 107 10 (18.2)
   > 1.0 × 107 45 (81.8)
HBV DNA (Log, copies/mL) 7.9 ± 1.1
Diagnosis of chronic hepatitis (Histopathological results)  
   Mild (grade 1–2, stage 0–2) 7 (12.7)
   Moderate (grade 3, stage 1–3) 40 (72.7)
   Severe (grade 4, stage 2–4) 8 (14.5)
  1. * CHB, chronic hepatitis B; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Normal values: ALT, ≤40 IU/L; AST, ≤40 IU/L; total bilirubin, ≤17.1 μmol/mL. † Date are expressed as mean ± SD; ‡ Data are expressed as no. (%).