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  1. Coronavirus disease 2019 (COVID-19) is an evolving global pandemic, and nanobodies, as well as other single-domain antibodies (sdAbs), have been recognized as a potential diagnostic and therapeutic tool for in...

    Authors: Fangfang Chen, Zhihong Liu, Wei Kang, Fan Jiang, Xixiao Yang, Feng Yin, Ziyuan Zhou and Zigang Li
    Citation: BMC Infectious Diseases 2024 24:199
    Content type: Research Published on:

  2. Drug-resistant tuberculosis (DR-TB) is a major public health threat in Hunan Province, with an increasing clinical burden in recent years. This study aimed to identify socio-demographic and clinical factors as...

    Authors: Temesgen Yihunie Akalu, Archie C. A. Clements, Zuhui Xu, Liqiong Bai and Kefyalew Addis Alene
    Citation: BMC Infectious Diseases 2024 24:198
    Content type: Research Published on:

  3. Autoimmune diseases (ADs) may be complicated by sepsis when intensive care unit (ICU) admission. But repeated sepsis among AD patients has not been studied yet. The aim of this study is to investigate the impa...

    Authors: Jinming Yang, Jie Chen, Min Zhang, Qingsa Zhou and Bing Yan
    Citation: BMC Infectious Diseases 2024 24:197
    Content type: Research Published on:

  4. Omicron has become the dominant variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since first reported in November 2021. From the initially detected Wuhan lineage, sublineages BA.2, BA.4,...

    Authors: Jaqueline Rhoden, Andressa Taíz Hoffmann, Janaína Franciele Stein, Mariana Soares da Silva, Juliana Schons Gularte, Micheli Filippi, Meriane Demoliner, Viviane Girardi, Fernando Rosado Spilki, Juliane Deise Fleck and Caroline Rigotto
    Citation: BMC Infectious Diseases 2024 24:193
    Content type: Research Published on:

  5. Food borne diseases is a challenging problem nowadays. Salmonella and Shigella species are great concern of food-born outbreaks. Thus, this study was aimed to assess the prevalence, antimicrobial susceptibility t...

    Authors: Tesfay Berihu, Guesh Gebremariam, Yemane Weldu, Amlsha Kahsay, Tsehaye Asmelash and Araya Gebreyesus
    Citation: BMC Infectious Diseases 2024 24:191
    Content type: Research Published on:

  6. The World Health Organization endorsed Truenat MTB rapid molecular assay in 2020 and recommended additional in-country evaluation studies before uptake. We evaluated the accuracy and operational feasibility of...

    Authors: Willy Ssengooba, Achilles Katamba, James Sserubiri, Derrick Semugenze, Abdunoor Nyombi, Raymond Byaruhanga, Stavia Turyahabwe and Moses L. Joloba
    Citation: BMC Infectious Diseases 2024 24:190
    Content type: Research Published on:

  7. Dexamethasone usually recommended for patients with severe coronavirus disease 2019 (COVID-19) to reduce short-term mortality. However, it is uncertain if another corticosteroid, such as methylprednisolone, ma...

    Authors: Ohoud Aljuhani, Ghazwa B. Korayem, Ali F. Altebainawi, Daniah AlMohammady, Amjaad Alfahed, Elaf F. Altebainawi, Mohammed Aldhaeefi, Hisham A. Badreldin, Ramesh Vishwakarma, Faisal E. Almutairi, Abeer A. Alenazi, Thamer Alsulaiman, Rahaf Ali Alqahtani, Fahad Al Dhahri, Namareq Aldardeer, Ahmed O. Alenazi…
    Citation: BMC Infectious Diseases 2024 24:189
    Content type: Research Published on:

  9. Metagenomic next-generation sequencing (mNGS) could improve the diagnosed efficiency of pathogens in bloodstream infections or sepsis. Little is known about the clinical impact of mNGS test when used for the e...

    Authors: Hui Zhang, Ruobing Liang, Yunzhu Zhu, Lifen Hu, Han Xia, Jiabin Li and Ying Ye
    Citation: BMC Infectious Diseases 2024 24:187
    Content type: Research Published on:

  10. In this study, we describe the patterns of antibiotic prescription for neonates based on World Health Organization’s (WHO) Essential Medicines List Access, Watch, and Reserve (AWaRe), and the Management of Ant...

    Authors: Jiaosheng Zhang, Li Lin, Gen Lu, Keye Wu, Daiyin Tian, Lanfang Tang, Xiang Ma, Yajuan Wang, Gang Liu, Yanqi Li, Jing Qian, Ping Wang, Qing Cao, Wenshuang Zhang, Lijuan Wu, Ligang Si…
    Citation: BMC Infectious Diseases 2024 24:186
    Content type: Research Published on:

  11. Timely access to outbreak related data, particularly in the early events of a spillover, is important to support evidence based control measures in response to outbreaks of zoonotic Emerging Infectious Disease...

    Authors: Martine Y. van Roode, Carolina dos S. Ribeiro, Elmoubasher Farag, Mohamed Nour, Aya Moustafa, Minahil Ahmed, George Haringhuizen, Marion P.G. Koopmans and Linda H.M. van de Burgwal
    Citation: BMC Infectious Diseases 2024 24:185
    Content type: Research Published on:

  12. Chronic comorbid conditions are common in patients with sepsis and may affect the outcomes. This study aimed to evaluate the prevalence and outcomes of common comorbidities in patients with sepsis.

    Authors: Christine Kang, Seongmi Choi, Eun Jin Jang, Somin Joo, Jae Hoon Jeong, Seung-Young Oh, Ho Geol Ryu and Hannah Lee
    Citation: BMC Infectious Diseases 2024 24:184
    Content type: Research Published on:

  13. The outbreak of mpox that occurred between 2022 and 2023 is primarily being transmitted through sexual contact. As of now, there is no consensus on the recommended duration of isolation to prevent sexual trans...

    Authors: Sung Un Shin, Younggon Jung, Seong Eun Kim and Dong Min Kim
    Citation: BMC Infectious Diseases 2024 24:183
    Content type: Case Report Published on:

  14. The human papillomavirus (HPV) infection may affect the miRNA expression pattern during cervical cancer (CC) development. To demonstrate the association between high-risk HPVs and the development of cervix dys...

    Authors: Ali Dehghani, Fardin Khajepour, Mohammad Dehghani, Ehsan Razmara, Mohammadreza Zangouey, Maryam Fekri Soofi Abadi, Reza Bahram Abadi Nezhad, Shahriar Dabiri and Masoud Garshasbi
    Citation: BMC Infectious Diseases 2024 24:182
    Content type: Research Published on:

  15. An increasing number of studies have described new and persistent symptoms and conditions as potential post-acute sequelae of SARS-CoV-2 infection (PASC). However, it remains unclear whether certain symptoms o...

    Authors: Yongkang Zhang, Alfonso Romieu-Hernandez, Tegan K. Boehmer, Eduardo Azziz-Baumgartner, Thomas W. Carton, Adi V. Gundlapalli, Julia Fearrington, Kshema Nagavedu, Katherine Dea, Erick Moyneur, Lindsay G. Cowell, Rainu Kaushal, Kenneth H. Mayer, Jon Puro, Sonja A. Rasmussen, Deepika Thacker…
    Citation: BMC Infectious Diseases 2024 24:181
    Content type: Research Published on:

  16. Pseudomonas nitroreducens is a non-fermenting, gram-negative, rod-shaped bacterium commonly inhabiting soil, particularly soil contaminated with oil brine. To our knowledge, no cases of human infection with P. ni...

    Authors: Naoya Itoh, Nana Akazawa, Makoto Yamaguchi, Hiromi Murakami and Kiyofumi Ohkusu
    Citation: BMC Infectious Diseases 2024 24:180
    Content type: Case Report Published on:

  17. During the COVID-19 pandemic swift implementation of research cohorts was key. While many studies focused exclusively on infected individuals, population based cohorts are essential for the follow-up of SARS-C...

    Authors: Olena Tsurkalenko, Dmitry Bulaev, Marc Paul O’Sullivan, Chantal Snoeck, Soumyabrata Ghosh, Alexey Kolodkin, Basile Rommes, Piotr Gawron, Carlos Vega Moreno, Clarissa P. C. Gomes, Anne Kaysen, Jochen Ohnmacht, Valerie E. Schröder, Lukas Pavelka, Guilherme Ramos Meyers, Laure Pauly…
    Citation: BMC Infectious Diseases 2024 24:179
    Content type: Research Published on:

  18. Lipoarabinomannan (LAM) antigen serves as an attractive biomarker to diagnose Tuberculosis (TB). Given the limitations of current diagnostic modalities for Pleural TB, current study evaluated LAM’s potential t...

    Authors: Atish Mohapatra, Ujjwala Gaikwad, Ranganath T. Ganga and Pratibha Sharma
    Citation: BMC Infectious Diseases 2024 24:178
    Content type: Research Published on:

  19. Human polyomaviruses contribute to human oncogenesis through persistent infections, but currently there is no effective preventive measure against the malignancies caused by this virus. Therefore, the developm...

    Authors: Reza Salahlou, Safar Farajnia, Nasrin Bargahi, Nasim Bakhtiyari, Faranak Elmi, Mehdi Shahgolzari, Steven Fiering and Srividhya Venkataraman
    Citation: BMC Infectious Diseases 2024 24:177
    Content type: Research Published on:

  21. Tuberculosis (TB) remains a significant public health burden in Sub-Saharan Africa (SSA), accounting for about 25% of global TB cases. In several communities, TB diagnosis, treatment, and control have become a...

    Authors: William Dormechele, Emmanuel Osei Bonsu, Caleb Boadi, Mercy Oseiwah Adams, Benedictus Atsu Hlormenu, Stephen Kwakye Addo, Bright Boatey Bossman and Isaac Yeboah Addo
    Citation: BMC Infectious Diseases 2024 24:175
    Content type: Research Published on:

  22. It is not yet fully understood to what extent in-flight transmission contributed to the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This study aimed to determine the occurrence and ...

    Authors: Joshua Howkins, Simon Packer, Eleanor Walsh, Deepti Kumar, Obaghe Edeghere, Matthew Hickman and Isabel Oliver
    Citation: BMC Infectious Diseases 2024 24:174
    Content type: Research Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2024 24:377

  23. Sepsis not only causes inflammation, but also damages the heart and increases the risk of death. The glycolytic pathway plays a crucial role in the pathogenesis of sepsis-induced cardiac injury. This study aim...

    Authors: Long Huang, Xincai Wang, Bawei Huang, Yu Chen and Xiaodan Wu
    Citation: BMC Infectious Diseases 2024 24:173
    Content type: Research Published on:

  24. Spontaneous miscarriage, a leading health concern globally, often occurs due to various factors, including infections. Among these, Coxiella burnetii and Brucella spp. may have adverse effects on pregnancy outcom...

    Authors: Neda Baseri, Amir Hossein Omidi, Mina Latifian, Ehsan Mostafavi, Shahram Khademvatan, Navid Omidifar, Seyyed javad Seyyed Tabaei, Rasool Jafari, Shiva Zeinali, Ahmad Ghasemi and Saber Esmaeili
    Citation: BMC Infectious Diseases 2024 24:172
    Content type: Research Published on:

  25. Syndromic surveillance of acute gastroenteritis plays a significant role in the diagnosis and management of gastrointestinal infections that are responsible for a substantial number of deaths globally, especia...

    Authors: Jad Mohtar, Hiba Mallah, Jean Marc Mardirossian, Rana El-Bikai, Tamima El Jisr, Shatha Soussi, Rania Naoufal, Gabriella Alam and Mira El Chaar
    Citation: BMC Infectious Diseases 2024 24:171
    Content type: Research Published on:

  26. Maternal sepsis is the third leading cause of maternal death in the world. Women in resource-limited countries shoulder most of the burdens related to sepsis. Despite the growing risk associated with maternal ...

    Authors: Bisrat Tesfay Abera, Hale Teka, Daniel Gebre, Tsega Gebremariam, Ephrem Berhe, Hagos Gidey, Birhane Amare, Rahel Kidanemariam, Marta Abrha Gebru, Fireweyni Tesfay, Yibrah Berhe Zelelow, Awol Yemane, Fanus Gebru, Ashenafi Tekle, Habtom Tadesse, Mohammedtahir Yahya…
    Citation: BMC Infectious Diseases 2024 24:170
    Content type: Research Published on:

  28. Leptospirosis is an underdiagnosed infectious disease with non-specific clinical presentation that requires laboratory confirmation for diagnosis. The serologic reference standard remains the microscopic agglu...

    Authors: Marta Valente, Justina Bramugy, Suzanne H. Keddie, Heidi Hopkins, Quique Bassat, Oliver Baerenbold, John Bradley, Jane Falconer, Ruth H. Keogh, Paul N. Newton, Mathieu Picardeau and John A. Crump
    Citation: BMC Infectious Diseases 2024 24:168
    Content type: Research Published on:

  30. In Burkina Faso, the prevalence of malaria has decreased over the past two decades, following the scale-up of control interventions. The successful development of malaria parasites depends on several climatic ...

    Authors: Nafissatou Traoré, Taru Singhal, Ourohiré Millogo, Ali Sié, Jürg Utzinger and Penelope Vounatsou
    Citation: BMC Infectious Diseases 2024 24:166
    Content type: Research Published on:

  32. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, Streptococcus pneumoniae and Staphylococcus aureus are major bacterial causes of lower respiratory tract infections (LRTIs...

    Authors: Tran Thi Ngoc Dung, Voong Vinh Phat, Chau Vinh, Nguyen Phu Huong Lan, Nguyen Luong Nha Phuong, Le Thi Quynh Ngan, Guy Thwaites, Louise Thwaites, Maia Rabaa, Anh T. K. Nguyen and Pham Thanh Duy
    Citation: BMC Infectious Diseases 2024 24:164
    Content type: Research Published on:

  33. Diagnosis of tuberculous meningitis (TBM) is hampered by the lack of a gold standard. Current microbiological tests lack sensitivity and clinical diagnostic approaches are subjective. We therefore built a diag...

    Authors: Trinh Huu Khanh Dong, Joseph Donovan, Nghiem My Ngoc, Do Dang Anh Thu, Ho Dang Trung Nghia, Pham Kieu Nguyet Oanh, Nguyen Hoan Phu, Vu Thi Ty Hang, Nguyen Van Vinh Chau, Nguyen Thuy Thuong Thuong, Le Van Tan, Guy E. Thwaites and Ronald B. Geskus
    Citation: BMC Infectious Diseases 2024 24:163
    Content type: Research Published on:

  35. Bloodstream infection of Klebsiella pneumoniae (BSI-KP) were associated with increased mortality. Klebsiella pneumoniae was tested to susceptible to colistin by E-test and broth microdilution method in clinical l...

    Authors: Tao Wang, Hongcheng Liu, Huiqing Huang, Yuesong Weng and Xiaojun Wang
    Citation: BMC Infectious Diseases 2024 24:161
    Content type: Research Published on:

  36. The pathological consequences of inflammation persist in people living with the human immunodeficiency virus (PLWH), regardless of the positive outcomes of highly active antiretroviral therapy (HAART). The cur...

    Authors: Sihle E. Mabhida, Zandile J. Mchiza, Kabelo Mokgalaboni, Sidney Hanser, Joel Choshi, Haskly Mokoena, Khanyisani Ziqubu, Charity Masilela, Bongani B. Nkambule, Duduzile E. Ndwandwe, André P. Kengne and Phiwayinkosi V. Dludla
    Citation: BMC Infectious Diseases 2024 24:160
    Content type: Research Published on:

  37. Multidrug-resistant tuberculosis (MDR-TB) is a global health threat associated with high morbidity and mortality rates. Diagnosis and treatment delays are associated with poor treatment outcomes in patients wi...

    Authors: Temesgen Yihunie Akalu, Archie C. A. Clements, Eyob Alemayehu Gebreyohannes, Zuhui Xu, Liqiong Bai and Kefyalew Addis Alene
    Citation: BMC Infectious Diseases 2024 24:159
    Content type: Research Published on:

  38. Healthcare-associated infections (HCAI) place a significant burden on healthcare systems globally. This systematic review and meta-analysis aimed to investigate the prevalence, risk factors, and aetiologic age...

    Authors: Gabriel Kambale Bunduki, Effita Masoamphambe, Tilly Fox, Janelisa Musaya, Patrick Musicha and Nicholas Feasey
    Citation: BMC Infectious Diseases 2024 24:158
    Content type: Research Published on:

  39. Accurate estimation of SARS-CoV-2 re-infection is crucial to understanding the connection between infection burden and adverse outcomes. However, relying solely on PCR testing results in underreporting. We pre...

    Authors: Lucie Richard, Rosane Nisenbaum, Karen Colwill, Sharmistha Mishra, Roya M. Dayam, Michael Liu, Cheryl Pedersen, Anne-Claude Gingras and Stephen W. Hwang
    Citation: BMC Infectious Diseases 2024 24:125
    Content type: Research Published on:

  40. Empyema necessitans (EN) is a rare condition characterized by pleural infection with pus spreading into adjacent soft tissues. Although Mycobacterium tuberculosis and Actinomyces israelii are common causative age...

    Authors: Tomoaki Nakamura, Kazuhiro Ishikawa, Naoki Murata, Kuniko Sato, Atsushi Kitamura, Nobuyoshi Mori and Torahiko Jinta
    Citation: BMC Infectious Diseases 2024 24:157
    Content type: Case Report Published on:

  41. Previous studies show increased morbidity in children who are HIV-exposed but uninfected (HEU) compared to children who are HIV-unexposed uninfected (HUU). We sought to evaluate the effects of prenatal HIV exp...

    Authors: Jessica E. Ray, Katherine R. Dobbs, Sidney O. Ogolla, Ibrahim I. Daud, David Midem, Maxwel M. Omenda, Amy S. Nowacki, James G. Beeson, Katherine R. Sabourin, Rosemary Rochford and Arlene E. Dent
    Citation: BMC Infectious Diseases 2024 24:156
    Content type: Research Published on:

  42. This study aimed to understand the basic situation of adults with human immunodeficiency virus (HIV) receiving antiretroviral therapy (ART) in Meigu County, Liangshan Yi Autonomous Prefecture. The information ...

    Authors: Li Yuan, Kaiyou Chen, Yuanfang Cai, Zhonghui Zhou, Ju Yang, Wuti Jiqu, Qirong Zhu, Hong Zhang, Shaowei Niu and Hui Sun
    Citation: BMC Infectious Diseases 2024 24:155
    Content type: Research Published on:

  43. Nocardiosis is a rare infection that typically results from inhalation of or inoculation with Nocardia organisms. It may cause invasive disease in immunocompromised patients. This case describes nocardiosis with ...

    Authors: Victor Arahirwa, Sahal Thahir, Lauren Hernandez and Zachary Inskeep Willis
    Citation: BMC Infectious Diseases 2024 24:154
    Content type: Case Report Published on:

  44. Current diagnoses of urinary tract infection (UTI) by standard urine culture (SUC) has significant limitations in sensitivity, especially for fastidious organisms, and the ability to identify organisms in poly...

    Authors: Marzieh Akhlaghpour, Emery Haley, Laura Parnell, Natalie Luke, Mohit Mathur, Richard A. Festa, Michael Percaccio, Jesus Magallon, Mariana Remedios-Chan, Alain Rosas, Jimin Wang, Yan Jiang, Lori Anderson and David Baunoch
    Citation: BMC Infectious Diseases 2024 24:153
    Content type: Research Published on:

  45. Pneumocystis jirovecii pneumonia (PJP) is a life-threatening and severe disease in immunocompromised hosts. A synergistic regimen based on the combination of sulfamethoxazole-trimethoprim (SMX-TMP) with caspof...

    Authors: Hao Li, Yihe Lu, Guoxin Tian, Yongxing Wu, Tianjun Chen, Jiangwei Zhang, Nan Hu, Xiaoning Wang, Yang Wang, Lan Gao, Jinqi Yan, Linjing Zhou and Qindong Shi
    Citation: BMC Infectious Diseases 2024 24:152
    Content type: Research Published on:

  46. Northern Italy was the first European country affected by the spread of the SARS-CoV-2, with the epicenter in the province of Bergamo.

    Authors: Bianca Maria Donida, Flavia Simonetta Pirola, Roberto Opizzi and Peter Assembergs
    Citation: BMC Infectious Diseases 2024 24:151
    Content type: Research Published on:

  47. Bacterial infections are considered a leading cause of hospitalization and death globally. There is still a need for a rapid and feasible biomarker for bacterial infections. Heparin-binding protein (HBP) was s...

    Authors: Amira Mohamed Taha, Khaled Abouelmagd, Mohamed Mosad Omar, Qasi Najah, Mohammed Ali, Mohammed Tarek Hasan, Sahar A. Allam, Roua Arian, Omar El Sayed Rageh and Mohamed Abd-ElGawad
    Citation: BMC Infectious Diseases 2024 24:150
    Content type: Research Published on:

  48. Sexually transmitted infections (STIs), particularly in the absence of viral suppression, increase the risk of HIV transmission to uninfected partners. We determined factors associated with having an unsuppres...

    Authors: Marceline Mapiye, Khuliso Ravhuhali, Alex de Voux and Tendesayi Kufa
    Citation: BMC Infectious Diseases 2024 24:148
    Content type: Research Published on:

  49. Niemann-Pick Disease type C is a fatal autosomal recessive lipid storage disorder caused by NPC1 or NPC2 gene mutations and characterized by progressive, disabling neurological deterioration and hepatosplenomegal...

    Authors: Chaoxin Tao, Min Zhao, Xiaohui Zhang, Jihong Hao, Qiuyue Huo, Jie Sun, Jiangtao Xing, Yuna Zhang, Jianhong Zhao and Huaipeng Huang
    Citation: BMC Infectious Diseases 2024 24:145
    Content type: Case Report Published on:

  50. Head lice are a main public health problem and the most important human ectoparasites and the use of pediculicides is the most common way to control it. One of the possible causes of treatment failure is the l...

    Authors: Eslam Moradi-Asl, Abedin Saghafipour, Amir Hamta, Zahra Taheri-Kharameh, Malek Abazari and Shabnam Asghari Jajin
    Citation: BMC Infectious Diseases 2024 24:143
    Content type: Research Published on:

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