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  1. In recent years, metagenomic Next-Generation Sequencing (mNGS) has increasingly been used for an accurate assumption-free virological diagnosis. However, the systematic workflow evaluation on clinical respirat...

    Authors: A. Bal, M. Pichon, C. Picard, J. S. Casalegno, M. Valette, I. Schuffenecker, L. Billard, S. Vallet, G. Vilchez, V. Cheynet, G. Oriol, S. Trouillet-Assant, Y. Gillet, B. Lina, K. Brengel-Pesce, F. Morfin…
    Citation: BMC Infectious Diseases 2018 18:537
    Content type: Technical advance Published on:

  2. Incarcerated people carry a high burden of infection, including blood-borne diseases (BBDs). It is also known that one million people contract a sexually transmitted infection (STI) every day worldwide, which ...

    Authors: Komal Chacowry Pala, Stéphanie Baggio, Nguyen Toan Tran, François Girardin, Hans Wolff and Laurent Gétaz
    Citation: BMC Infectious Diseases 2018 18:539
    Content type: Research article Published on:

  3. Increasing human immunodeficiency virus (HIV) testing is critical for HIV control. This study aimed to evaluate the interaction between social norms and self-efficacy on HIV testing among Chinese men who have ...

    Authors: Peizhen Zhao, Li Liu, Ye Zhang, Huanhuan Cheng, Bolin Cao, Chuncheng Liu, Cheng Wang, Bin Yang, Chongyi Wei, Joseph D. Tucker and Weiming Tang
    Citation: BMC Infectious Diseases 2018 18:541
    Content type: Research article Published on:

  4. Enteric viruses in surface water pose considerable risk to morbidity in populations living around water catchments and promote outbreaks of waterborne diseases. However, due to poor understanding of the correl...

    Authors: Jing Miao, Xuan Guo, Weili Liu, Dong Yang, Zhiqiang Shen, Zhigang Qiu, Xiang Chen, Kunming Zhang, Hui Hu, Jing Yin, Zhongwei Yang, Junwen Li and Min Jin
    Citation: BMC Infectious Diseases 2018 18:542
    Content type: Research article Published on:

  5. China had the third highest burden of tuberculosis population in the world. Bone and joint tuberculosis was a major part and its characteristics were rarely discussed before. This study was designed to review ...

    Authors: Yun Qian, Qixin Han, Wenjun Liu, Wei-En Yuan and Cunyi Fan
    Citation: BMC Infectious Diseases 2018 18:543
    Content type: Research article Published on:

  6. Classification of pathogenic Escherichia coli (E. coli) has traditionally relied on detecting specific virulence associated genes (VAGs) or combinations thereof. For E. coli isolated from faecal samples, the pres...

    Authors: Bjørn-Arne Lindstedt, Misti D. Finton, Davide Porcellato and Lin T. Brandal
    Citation: BMC Infectious Diseases 2018 18:544
    Content type: Research article Published on:

  7. The East African region is endemic with multiple zoonotic diseases and is one of the hotspots for emerging infectious zoonotic diseases with reported multiple outbreaks of epidemic diseases such as Ebola, Marb...

    Authors: Naomi Kemunto, Eddy Mogoa, Eric Osoro, Austin Bitek, M. Kariuki Njenga and S. M. Thumbi
    Citation: BMC Infectious Diseases 2018 18:545
    Content type: Research article Published on:

  8. In recent decades the epidemic of asymptomatic sexually transmitted infections has extended deep into Brazil, including small towns and rural areas. The purpose of this study was to investigate the epidemiolog...

    Authors: Déborah Ferreira Noronha de Castro Rocha, Luana Rocha da Cunha Rosa, Carla de Almeida Silva, Brunna Rodrigues de Oliveira, Thaynara Lorrane Silva Martins, Regina Maria Bringel Martins, Marcos André de Matos, Megmar Aparecida dos Santos Carneiro, Juliana Pontes Soares, Ana Cristina de Oliveira e Silva, Márcia Maria de Souza, Robert L. Cook, Karlla Antonieta Amorim Caetano and Sheila Araujo Teles
    Citation: BMC Infectious Diseases 2018 18:546
    Content type: Research article Published on:

  9. The Leuconostoc mesenteroides are members of the Streptococcae family and currently has been recognized as potential pathogens. This case describes a bacteremia caused by L. mesenteroides in an immunocompetent pa...

    Authors: Mayra Gonçalves Menegueti, Gilberto Gambero Gaspar, Ana Maria Laus, Anibal Basile-Filho, Fernando Bellissimo-Rodrigues and Maria Auxiliadora-Martins
    Citation: BMC Infectious Diseases 2018 18:547
    Content type: Case report Published on:

  10. On 28 March, 2016, the Ministry of Health received a report on three deaths from an unknown disease characterized by fever, jaundice, and hemorrhage which occurred within a one-month period in the same family ...

    Authors: Leocadia Kwagonza, Ben Masiira, Henry Kyobe-Bosa, Daniel Kadobera, Emily B. Atuheire, Bernard Lubwama, Atek Kagirita, Edson Katushabe, John T. Kayiwa, Julius J. Lutwama, Joseph C. Ojwang, Issa Makumbi, Alex Riolexus Ario, Jeff Borchert and Bao-Ping Zhu
    Citation: BMC Infectious Diseases 2018 18:548
    Content type: Research article Published on:

  11. Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with simila...

    Authors: Simon C. Masha, Piet Cools, Patrick Descheemaeker, Marijke Reynders, Eduard J. Sanders and Mario Vaneechoutte
    Citation: BMC Infectious Diseases 2018 18:549
    Content type: Research article Published on:

  12. The Study of Healthcare Personnel with Influenza and other Respiratory Viruses in Israel (SHIRI) prospectively follows a cohort of healthcare personnel (HCP) in two hospitals in Israel. SHIRI will describe the fr...

    Authors: Avital Hirsch, Mark A. Katz, Alon Laufer Peretz, David Greenberg, Rachael Wendlandt, Yonat Shemer Avni, Gabriella Newes-Adeyi, Ilan Gofer, Maya Leventer-Roberts, Nadav Davidovitch, Anat Rosenthal, Rachel Gur-Arie, Tomer Hertz, Aharona Glatman-Freedman, Arnold S. Monto, Eduardo Azziz-Baumgartner…
    Citation: BMC Infectious Diseases 2018 18:550
    Content type: Study protocol Published on:

  14. Genetic mutations that reduce intracellular superoxide production by granulocytes causes chronic granulomatous disease (CGD). These patients suffer from frequent and severe bacterial and fungal infections thro...

    Authors: Esmaeil Mortaz, Somayeh Sarhifynia, Majid Marjani, Afshin Moniri, Davood Mansouri, Payam Mehrian, Karin van Leeuwen, Dirk Roos, Johan Garssen, Ian M. Adcock and Payam Tabarsi
    Citation: BMC Infectious Diseases 2018 18:552
    Content type: Case report Published on:

  15. Clinical progression of HBV-related liver diseases is largely associated with the activity of HBV-specific T cells. Soluble fibrinogen-like protein 2 (sFGL2), mainly secreted by T cells, is an important effect...

    Authors: Hoang Van Tong, Nguyen Van Ba, Nghiem Xuan Hoan, Mai Thanh Binh, Dao Thanh Quyen, Ho Anh Son, Hoang Van Luong, Do Quyet, Christian G. Meyer, Le Huu Song, Nguyen Linh Toan and Thirumalaisamy P. Velavan
    Citation: BMC Infectious Diseases 2018 18:553
    Content type: Research article Published on:

  16. Cytomegalovirus (CMV) reactivation with neurological involvement in patients with acquired immunodeficiency syndrome (AIDS) is increasingly rare since the introduction of antiretroviral therapy (ART). Manifest...

    Authors: Pedro Palma, Andreia Costa, Raquel Duro, Nélia Neves, Cândida Abreu and António Sarmento
    Citation: BMC Infectious Diseases 2018 18:554
    Content type: Case report Published on:

  17. Infection after vertebroplasty (VP) is a rare but serious complication. Previous literatures showed most pathogens for infection after VP were bacteria; tuberculosis (TB) induced infection after VP was extreme...

    Authors: Jen-Chung Liao, Po-Liang Lai, Lih-Hui Chen and Chi-Chien Niu
    Citation: BMC Infectious Diseases 2018 18:555
    Content type: Research article Published on:

  18. Nevirapine has been used as antiretroviral agent since early ‘90. Although nevirapine is not currently recommended in initial anti-HIV regimens, its use remains consistent in a certain number of HIV-1-positive...

    Authors: Andrea Giacomelli, Agostino Riva, Felicia Stefania Falvella, Maria Letizia Oreni, Dario Cattaneo, Stefania Cheli, Giulia Renisi, Valentina Di Cristo, Angelica Lupo, Emilio Clementi, Stefano Rusconi, Massimo Galli and Anna Lisa Ridolfo
    Citation: BMC Infectious Diseases 2018 18:556
    Content type: Research article Published on:

  19. Globally recommended measures for comprehensive tuberculosis (TB) infection control (IC) are inadequately practiced in most health care facilities in Ethiopia. The aim of this study was to assess the extent of...

    Authors: Asfaw Ayalew, Zewdu Gashu, Tadesse Anteneh, Nebiyu Hiruy, Dereje Habte, Degu Jerene, Genetu Alem, Ilili Jemal, Muluken Melese and Pedro G. Suarez
    Citation: BMC Infectious Diseases 2018 18:557
    Content type: Research article Published on:

  20. The prevalence and risk factors for persistent candidemia among very low birth weight infants are poorly understood. This study aimed to investigate the epidemiology of persistent candidemia over a 4-year peri...

    Authors: Jinjian Fu, Yanling Ding, Yongjiang Jiang, Shengfu Mo, Shaolin Xu and Peixu Qin
    Citation: BMC Infectious Diseases 2018 18:558
    Content type: Research article Published on:

  21. Chlamydia trachomatis (chlamydia), the most commonly reported sexually transmitted infection (STI) in the Netherlands, can lead to severe reproductive complications. Reasons for the sustained chlamydia prevalence...

    Authors: Daphne A. van Wees, Janneke C. M. Heijne, Titia Heijman, Karlijn C. J. G. Kampman, Karin Westra, Anne de Vries, Mirjam E. E. Kretzschmar and Chantal den Daas
    Citation: BMC Infectious Diseases 2018 18:559
    Content type: Study protocol Published on:

  22. Methicillin resistant Staphylococcus aureus (MRSA) is recognized worldwide as a leading cause of hospital and community infections. Biofilm formation by MRSA is an extremely important virulence factor to be under...

    Authors: Ons Haddad, Abderrahmen Merghni, Aida Elargoubi, Hajer Rhim, Yosr Kadri and Maha Mastouri
    Citation: BMC Infectious Diseases 2018 18:560
    Content type: Research article Published on:

  23. Toll-like receptor (TLR) single nucleotide polymorphisms (SNPs) have been associated with regulation of TLR expression and development of active tuberculosis (TB). The objectives of this study were to determine w...

    Authors: Ming-Gui Wang, Miao-Miao Zhang, Yu Wang, Shou-Quan Wu, Meng Zhang and Jian-Qing He
    Citation: BMC Infectious Diseases 2018 18:561
    Content type: Research article Published on:

  24. Although HIV prevalence in Cambodia has declined to 0.6% among the general population, the prevalence remains high among female sex workers (14.0%) and men who have sex with men (2.3%). Over the past 10 years,...

    Authors: Heng Sopheab, Chhorvann Chhea, Sovannary Tuot and Jonathan A. Muir
    Citation: BMC Infectious Diseases 2018 18:562
    Content type: Research article Published on:

  25. In recent years, outbreaks of varicella have continued to occur, and the coverage rate of varicella vaccine in Jiangsu Province, China, remains unclear. This study aims to analyse the levels of immune antibody...

    Authors: Lei Zhang, Wang Ma, Yuanbao Liu, Yong Wang, Xiang Sun, Ying Hu, Xiuying Deng, Peishan Lu, Fenyang Tang, Zhiguo Wang and Minghao Zhou
    Citation: BMC Infectious Diseases 2018 18:563
    Content type: Research article Published on:

  26. There are randomized trials assessing a variety of antiviral drugs for hepatitis B virus (HBV), but the relative effectiveness of these drugs in the treatment of patients co-infected with human immunodeficienc...

    Authors: Cho Naing, Yong Poovorawan and Kew Siang Tong
    Citation: BMC Infectious Diseases 2018 18:564
    Content type: Research article Published on:

  27. By 2014 although tuberculosis (TB) incidence had fallen by an average of 1.5% per year since 2000 and was 18% lower than the level of in 2000, 1.5 million people died for TB in that year. One of reason was tha...

    Authors: Tao Shi, Tongxin Li, Jungang Li, Jing Wang and Zehua Zhang
    Citation: BMC Infectious Diseases 2018 18:565
    Content type: Research article Published on:

  28. Prevention of mother to child transmission (PMTCT) has lowered the incidence of paediatric HIV globally. The risk of mother-to-child transmission of HIV (MTCT) remains high in Africa, where there is a high pre...

    Authors: Mariama Mustapha, Victor Musiime, Sabrina Bakeera-Kitaka, Joseph Rujumba and Nicolette Nabukeera-Barungi
    Citation: BMC Infectious Diseases 2018 18:566
    Content type: Research article Published on:

  29. Prior to the 2009 pandemic H1N1, and the unprecedented outbreak of Highly Pathogenic Avian Influenza (HPAI) caused by the H5N1 virus, the World Health Organization (WHO) called upon its Member States to develo...

    Authors: Evanson Z. Sambala, Tiwonge Kanyenda, Chinwe Juliana Iwu, Chidozie Declan Iwu, Anelisa Jaca and Charles S. Wiysonge
    Citation: BMC Infectious Diseases 2018 18:567
    Content type: Research article Published on:

  30. Hepatitis B virus (HBV) genotype E is a poorly studied genotype that almost exclusively occurs in African people. It seems to harbour intrinsic potential oncogenic activity and virological characteristics of i...

    Authors: José Ángel Cuenca-Gómez, Ana Belén Lozano-Serrano, María Teresa Cabezas-Fernández, Manuel Jesús Soriano-Pérez, José Vázquez-Villegas, Matías Estévez-Escobar, Isabel Cabeza-Barrera and Joaquín Salas-Coronas
    Citation: BMC Infectious Diseases 2018 18:568
    Content type: Research article Published on:

  31. Leptospirosis is a zoonotic disease associated with occupations which exposed workers to environments contaminated with urine of infected animals. The objective of this study was to determine the seroprevalenc...

    Authors: Mas Harithulfadhli Agus Ab Rahman, Suhaily Mohd Hairon, Rukman Awang Hamat, Tengku Zetty Maztura Tengku Jamaluddin, Mohd Nazri Shafei, Norazlin Idris, Malina Osman, Surianti Sukeri, Zainudin A. Wahab, Wan Mohd Zahiruddin Wan Mohammad, Zawaha Idris and Aziah Daud
    Citation: BMC Infectious Diseases 2018 18:569
    Content type: Research article Published on:

  32. Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study is one of a few to eva...

    Authors: Bernhard Kerschberger, Qhubekani Mpala, Paola Andrea Díaz Uribe, Gugu Maphalala, Roberto de la Tour, Sydney Kalombola, Addis Bekele, Tiwonge Chawinga, Mukelo Mliba, Nombuso Ntshalintshali, Nomcebo Phugwayo, Serge Mathurin Kabore, Javier Goiri, Sindisiwe Dlamini, Iza Ciglenecki and Emmanuel Fajardo
    Citation: BMC Infectious Diseases 2018 18:570
    Content type: Research article Published on:

  33. HIV/AIDS patients who fail to respond to first-line treatment protocols are switched to second-line ART. Identifying factors that influence effective second-line treatment can improve utilization of limited me...

    Authors: Junli Chen, Min Zhang, Mingquan Shang, Weiwei Yang, Zhe Wang and Hong Shang
    Citation: BMC Infectious Diseases 2018 18:571
    Content type: Research article Published on:

  34. Urinary tract infections (UTIs) are one of the most frequent diseases encountered by humans worldwide. The presence of multidrug-resistant (MDR) uropathogenic Escherichia coli (UPEC) harboring several virulence f...

    Authors: Yalda Malekzadegan, Reza Khashei, Hadi Sedigh Ebrahim-Saraie and Zahra Jahanabadi
    Citation: BMC Infectious Diseases 2018 18:572
    Content type: Research article Published on:

  35. Cytomegalovirus (CMV) prophylaxis may prevent CMV indirect effects in renal transplant recipients. This study aimed to compare the efficacy of valganciclovir and valacyclovir prophylaxis for CMV after renal tr...

    Authors: Tomas Reischig, Martin Kacer, Petra Hruba, Hana Hermanova, Ondrej Hes, Daniel Lysak, Stanislav Kormunda and Mirko Bouda
    Citation: BMC Infectious Diseases 2018 18:573
    Content type: Research article Published on:

  36. The enteric string test can be used to obtain a specimen for microbiological confirmation of tuberculosis in children, but it is not widely used for this. The aim of this analysis to evaluate this approach in ...

    Authors: Karla T. Tafur, Julia Coit, Segundo R. Leon, Cynthia Pinedo, Silvia S. Chiang, Carmen Contreras, Roger Calderon, Milagros J. Mendoza, Leonid Lecca and Molly F. Franke
    Citation: BMC Infectious Diseases 2018 18:574
    Content type: Research article Published on:

  37. To investigate the associations between the perceived barriers and benefits of using HIV pre-exposure prophylaxis medication, including worries about the side effects, disliking taking drugs, perceived burden ...

    Authors: Ying Hu, Xiao-ni Zhong, Bin Peng, Yan Zhang, Hao Liang, Jiang-hong Dai, Ju-ying Zhang and Ai-long Huang
    Citation: BMC Infectious Diseases 2018 18:575
    Content type: Research article Published on:

  38. Since macrophages are one of the major cell types involved in the Mycobacterium leprae immune response, roles of the M1 and M2 macrophage subpopulations have been well defined. However, the role of M4 macrophages...

    Authors: Jorge Rodrigues de Sousa, Francisco Dias Lucena Neto, Mirian Nacagami Sotto and Juarez Antonio Simões Quaresma
    Citation: BMC Infectious Diseases 2018 18:576
    Content type: Research article Published on:

  39. Studies on human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) have focused primarily on the immunosuppressed population. Few studies have considered immunocompetent and not severely immunocompromised pa...

    Authors: Jianhua Hu, Hong Zhao, Danfeng Lou, Hainv Gao, Meifang Yang, Xuan Zhang, Hongyu Jia and Lanjuan Li
    Citation: BMC Infectious Diseases 2018 18:577
    Content type: Research article Published on:

  40. Seoul virus (SEOV) is a member of hantavirus family, which is transmitted to humans by Rattus rattus and Rattus norvegicus. Diagnosing SEOV infection is difficult because the clinical presentations are often undi...

    Authors: Khie Chen Lie, Mochamad Helmi Aziz, Herman Kosasih, Aaron Neal, Caleb Leonardo Halim, Wahyu Nawang Wulan, Muhammad Karyana and Usman Hadi
    Citation: BMC Infectious Diseases 2018 18:578
    Content type: Case report Published on:

  41. Influenza A H1N1 infections carry a significant mortality risk. This study describes inpatients with suspected and confirmed Influenza A H1N1 infection who were prescribed oseltamivir, the risk factors associa...

    Authors: Talita Rantin Belucci, Alexandre R. Marra, Michael B. Edmond, João Renato Rebello Pinho, Paula Kiyomi Onaga Yokota, Ana Carolina Cintra Nunes Mafra and Oscar Fernando Pavão dos Santos
    Citation: BMC Infectious Diseases 2018 18:579
    Content type: Research article Published on:

  42. According to the EASL and AASLD guidelines, the recommended treatment for patients who failed to achieve a sustained virologic response (SVR) on prior interferon-based triple therapy with protease inhibitors (...

    Authors: Ewa Janczewska, Dorota Zarębska-Michaluk, Hanna Berak, Anna Piekarska, Andrzej Gietka, Dorota Dybowska, Włodzimierz Mazur, Teresa Belica-Wdowik, Witold Dobracki, Magdalena Tudrujek-Zdunek, Zbigniew Deroń, Iwona Buczyńska, Marek Sitko, Agnieszka Czauż-Andrzejuk, Beata Lorenc, Jolanta Białkowska-Warzecha…
    Citation: BMC Infectious Diseases 2018 18:580
    Content type: Research article Published on:

  43. Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent on...

    Authors: David Sidebottom, Anna Mia Ekström and Susanne Strömdahl
    Citation: BMC Infectious Diseases 2018 18:581
    Content type: Research article Published on:

  44. Cervical cancer (CC) is caused by a persistent infection of high-risk human papillomavirus (HR-HPV). While most HPV infections are transient, persistent HPV infections are a significant health problem in Mexic...

    Authors: K. Torres-Poveda, M. Bahena-Román, K. Delgado-Romero and V. Madrid-Marina
    Citation: BMC Infectious Diseases 2018 18:582
    Content type: Study protocol Published on:

  45. Environmental cleaning practice plays an important role in reducing microbial contamination in hospital surfaces and contributes to prevent Healthcare Associated Infections. Adenosine Triphosphate (ATP) biolum...

    Authors: Tiziana Sanna, Laura Dallolio, Alessandra Raggi, Magda Mazzetti, Giovanni Lorusso, Angela Zanni, Patrizia Farruggia and Erica Leoni
    Citation: BMC Infectious Diseases 2018 18:583
    Content type: Research article Published on:

  46. The aim was to evaluate the value of organ-specific weighted incidence antibiogram (OSWIA) percentages for bacterial susceptibilities of Gram-negative bacteria (GNB) collected from intra-abdominal infections (...

    Authors: Lianxin Liu and Yuxing Ni
    Citation: BMC Infectious Diseases 2018 18:584
    Content type: Research article Published on:

  47. In developing countries, tuberculosis (TB) is a major public health problem and the leading cause of death among patients with HIV (Human Immunodeficiency Virus). Until 2001, the tuberculin skin test (TST) was...

    Authors: Giselle Burlamaqui Klautau, Nadijane Valéria Ferreira da Mota, Mauro José Costa Salles, Marcelo Nascimento Burattini and Denise Silva Rodrigues
    Citation: BMC Infectious Diseases 2018 18:585
    Content type: Research article Published on:

  48. Schistosoma mansoni infection has been associated with increased risk of HIV transmission in African women. This association might be causal or mediated through shared socio-behavioural factors and associated co-...

    Authors: Sergey Yegorov, Ronald M. Galiwango, Sara V. Good, Juliet Mpendo, Egbert Tannich, Andrea K. Boggild, Noah Kiwanuka, Bernard S. Bagaya and Rupert Kaul
    Citation: BMC Infectious Diseases 2018 18:586
    Content type: Research article Published on:

  49. Successful treatment of latent tuberculosis infection (LTBI) is essential to reduce tuberculosis (TB) incidence rates in low-burden countries. This study measures treatment completion and determinants of non-c...

    Authors: Yvette Louise Schein, Tesfaye Madebo, Hilde Elise Andersen, Trude Margrete Arnesen, Anne Ma Dyrhol-Riise, Hallgeir Tveiten, Richard A. White and Brita Askeland Winje
    Citation: BMC Infectious Diseases 2018 18:587
    Content type: Research article Published on:

  50. Men with urinary retention secondary to benign prostatic hyperplasia (BPH) are prone to genitourinary infections. Physicians should be aware of the current antimicrobial susceptibility pattern in this populati...

    Authors: Bartosz A. Dybowski, Piotr Zapała, Ewa Bres-Niewada, Łukasz Zapała, Nina Miązek-Zapała, Sławomir Poletajew, Grażyna Młynarczyk and Piotr Radziszewski
    Citation: BMC Infectious Diseases 2018 18:590
    Content type: Research article Published on:

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