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  1. Daily throughout 2011, about 900 new HIV infections occurred in children and 630 children died as a result of AIDS-related complications worldwide. Late diagnosis, mortality trends, causes of and risk factors ...

    Authors: Sandra Fagundes Moreira-Silva, Eliana Zandonade and Angélica Espinosa Miranda
    Citation: BMC Infectious Diseases 2015 15:155
  2. Healthcare-associated infections (HAIs) are a frequent complication associated with hospitalization of infants in neonatal intensive care units (NICUs). The aim of this study was to evaluate and describe the r...

    Authors: Valeria Crivaro, Lidija Bogdanović, Maria Bagattini, Vita Dora Iula, Mariarosaria Catania, Francesco Raimondi, Maria Triassi and Raffaele Zarrilli
    Citation: BMC Infectious Diseases 2015 15:152
  3. Respiratory syncytial virus (RSV) infection is a common cause of pediatric hospitalization. microRNA, key regulators of the immune system, have not previously been investigated in respiratory specimens during ...

    Authors: Christopher S Inchley, Tonje Sonerud, Hans O Fjærli and Britt Nakstad
    Citation: BMC Infectious Diseases 2015 15:150
  4. Several studies suggested that vaccines could have non-specific effects on mortality depending on the type of vaccine. Non-specific effects seem to be different in boys and girls. In this study we want to inve...

    Authors: Tessa M Schurink-van’t Klooster, Mirjam J Knol, Hester E de Melker and Marianne AB van der Sande
    Citation: BMC Infectious Diseases 2015 15:148
  5. Schistosoma mansoni infection represents a major cause of morbidity and mortality in many areas of the developing world. Effective vaccines against schistosomiasis are not available and disease management relies ...

    Authors: Shereen F Mossallam, Eglal I Amer, Radwa E Ewaisha, Amal M Khalil, Hamida M Aboushleib and Mohammed Bahey-El-Din
    Citation: BMC Infectious Diseases 2015 15:147
  6. Hand, foot, and mouth disease (HFMD) is the most common communicable disease in China. Shandong Province is one of the most seriously affected areas. The distribution of HFMD had spatial heterogeneity and seas...

    Authors: Yunxia Liu, Xianjun Wang, Chunkun Pang, Zhongshang Yuan, Hongkai Li and Fuzhong Xue
    Citation: BMC Infectious Diseases 2015 15:146
  7. Pulmonary exacerbations (PEx) are critical events in cystic fibrosis (CF), responsible for reduced quality of life and permanent loss of lung function. Approximately 1/4 of PEx are associated with failure to r...

    Authors: John C Lam, Ranjani Somayaji, Michael G Surette, Harvey R Rabin and Michael D Parkins
    Citation: BMC Infectious Diseases 2015 15:145
  8. Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting. Modelling mass ...

    Authors: Jaline Gerardin, Philip Eckhoff and Edward A Wenger
    Citation: BMC Infectious Diseases 2015 15:144
  9. After the 2009 influenza A(H1N1)pdm09 pandemic, China established its first severe acute respiratory infections (SARI) sentinel surveillance system.

    Authors: Zhibin Peng, Luzhao Feng, Greene M Carolyn, Kaili Wang, Guozhong Zhu, Yequn Zhang, Jumei Hu, Yiwei Huang, Huiqiong Pan, Nongjian Guo, Chunyan Xing, Yanhui Chu, Zhaolong Cao, Deshan Yu, Linling Liu, Zeling Chen…
    Citation: BMC Infectious Diseases 2015 15:143
  10. An outbreak of dengue virus (DENV) occurred in Yunnan province. More than 2,000 individuals were infected from August to November 2013. In this study, we aimed to characterize the origin and prevalence of DENV...

    Authors: Binghui Wang, Yaping Li, Yue Feng, Hongning Zhou, Yaobo Liang, Jiejie Dai, Weihong Qin, Yunzhang Hu, Yajuan Wang, Li Zhang, Zulqarnain Baloch, Henglin Yang and Xueshan Xia
    Citation: BMC Infectious Diseases 2015 15:142
  11. The recent emergence of Clostridium difficile infections has included this condition among top nosocomial infections, due to its incidence, complications and important fatality, as well as to significant economic...

    Authors: Ruxandra Laza, Ruxandra Jurac, Alexandru Crişan, Voichiţa Lăzureanu, Monica Licker, Emilian Damian Popovici and Luminiţa Mirela Bădiţoiu
    Citation: BMC Infectious Diseases 2015 15:141
  12. Fungal skull base osteomyelitis (SBO) is a severe complication of otitis externa or sinonasal infection, and is mainly caused by Aspergillus species. Here we investigate innate and adaptive immune responses in pa...

    Authors: Corine E Delsing, Katharina L Becker, Anna Simon, Bart Jan Kullberg, Chantal P Bleeker-Rovers, Frank L van de Veerdonk and Mihai G Netea
    Citation: BMC Infectious Diseases 2015 15:140
  13. In limited resource settings, sputum smear conversion at the end of the intensive phase of tuberculosis treatment is an indicator not only of patients’ response to treatment, but also of anti-tuberculosis prog...

    Authors: Fabrice Nembot Djouma, Michel Noubom, Jérôme Ateudjieu and Hubert Donfack
    Citation: BMC Infectious Diseases 2015 15:139
  14. Increased levels of markers of systemic inflammation have been associated with serious non-AIDS events even in patients on fully suppressive antiretroviral therapy. We explored residual viremia and systemic in...

    Authors: Alejandro Arenas-Pinto, Ana Milinkovic, Dimitra Peppa, Anna McKendry, Mala Maini and Richard Gilson
    Citation: BMC Infectious Diseases 2015 15:138
  15. Elderly people are at increased risk for severe influenza illness and constitute therefore a major target-group for seasonal influenza vaccination in most industrialized countries. The aim of this study was to...

    Authors: Cornelius Remschmidt, Thorsten Rieck, Birte Bödeker and Ole Wichmann
    Citation: BMC Infectious Diseases 2015 15:137
  16. Some studies have suggested that helminth infections increase the risk of malaria infection and are associated with increased number of malaria attacks and anaemia. Thus interventions to control helminth infec...

    Authors: Safari M Kinung’hi, Pascal Magnussen, Coleman Kishamawe, Jim Todd and Birgitte J Vennervald
    Citation: BMC Infectious Diseases 2015 15:136
  17. Infectious disease surveillance has recently seen many changes including rapid growth of informal surveillance, acting both as competitor and a facilitator to traditional surveillance, as well as the implement...

    Authors: Chi Y Bahk, David A Scales, Sumiko R Mekaru, John S Brownstein and Clark C Freifeld
    Citation: BMC Infectious Diseases 2015 15:135
  18. Recently we developed and validated generic quality indicators that define ‘appropriate antibiotic use’ in hospitalized adults treated for a (suspected) bacterial infection. Previous studies have shown that wi...

    Authors: Frederike V van Daalen, Jan M Prins, Brent C Opmeer, Marja A Boermeester, Caroline E Visser, Reinier M van Hest, Marlies E J L Hulscher and Suzanne E Geerlings
    Citation: BMC Infectious Diseases 2015 15:134
  19. Insulin resistance is a strong predictor of the development of type 2 diabetes mellitus. Chronic helminth infections might protect against insulin resistance via a caloric restriction state and indirectly via ...

    Authors: Dicky L Tahapary, Karin de Ruiter, Ivonne Martin, Lisette van Lieshout, Bruno Guigas, Pradana Soewondo, Yenny Djuardi, Aprilianto E Wiria, Oleg A Mayboroda, Jeanine J Houwing-Duistermaat, Hengki Tasman, Erliyani Sartono, Maria Yazdanbakhsh, Johannes W A Smit and Taniawati Supali
    Citation: BMC Infectious Diseases 2015 15:133
  20. In Nigeria, reports of the outcomes of prevention of mother to child transmission of HIV (PMTCT) interventions had been limited to the MTCT rates of HIV, with no information on HIV-free survival (HFS) in the H...

    Authors: Emmanuel A Anígilájé, Othniel J Dabit, Ayodotun Olutola, Bem Ageda and Sunday A Aderibigbe
    Citation: BMC Infectious Diseases 2015 15:132
  21. We have recovered one blaNDM-1-harboring bacterial strain, designated as XM1570, from a sputum sample obtained from a fatal case of pneumonia in China.

    Authors: Peng Li, Chaojie Yang, Jing Xie, Nan Liu, Houzhao Wang, Ling Zhang, Xu Wang, Yong Wang, Shaofu Qiu and Hongbin Song
    Citation: BMC Infectious Diseases 2015 15:131
  22. Achieving the goal of eliminating mother-to-child HIV transmission (MTCT) necessitates increased access to antiretroviral therapy (ART) for HIV-infected pregnant women. Option B provides ART through pregnancy ...

    Authors: Adam VanDeusen, Elijah Paintsil, Thomas Agyarko-Poku and Elisa F Long
    Citation: BMC Infectious Diseases 2015 15:130
  23. Antibiotic-associated diarrhea (AAD) is a common adverse effect of antibiotic (AB) treatment. This study aimed to measure the overall prevalence of AAD (including mild to moderate diarrhea) in hospitalized AB ...

    Authors: Monique M Elseviers, Yoleen Van Camp, Sander Nayaert, Khyra Duré, Lieven Annemans, Ann Tanghe and Sebastian Vermeersch
    Citation: BMC Infectious Diseases 2015 15:129
  24. Antifungal prophylaxis is a promising strategy for reducing invasive fungal infections (IFIs) in allogeneic hematopoietic cell transplant (alloHCT) recipients, but the optimum prophylactic agent is unknown. We...

    Authors: Eric J Bow, David J Vanness, Monica Slavin, Catherine Cordonnier, Oliver A Cornely, David I Marks, Antonio Pagliuca, Carlos Solano, Lael Cragin, Alissa J Shaul, Sonja Sorensen, Richard Chambers, Michal Kantecki, David Weinstein and Haran Schlamm
    Citation: BMC Infectious Diseases 2015 15:128
  25. Antibiotic resistance is a threat in developing countries (DCs) because of the high burden of bacterial disease and the presence of risk factors for its emergence and spread. This threat is of particular conce...

    Authors: Bich-Tram Huynh, Michael Padget, Benoit Garin, Perlinot Herindrainy, Elsa Kermorvant-Duchemin, Laurence Watier, Didier Guillemot and Elisabeth Delarocque-Astagneau
    Citation: BMC Infectious Diseases 2015 15:127
  26. The available pharmacokinetic data on anti-tubercular drugs in children raises the concern of suboptimal plasma concentrations attained when doses extrapolated from adult studies are used. Also, there is lack ...

    Authors: Aparna Mukherjee, Thirumurthy Velpandian, Mohit Singla, Kunwar Kanhiya, Sushil K Kabra and Rakesh Lodha
    Citation: BMC Infectious Diseases 2015 15:126
  27. There is little data regarding the effect of ramping up new screening interventions on their uptake by target populations into routine care services in developing countries. This study aimed to determine patie...

    Authors: Edward Tieru Dassah, Yaw Adu-Sarkodie and Philippe Mayaud
    Citation: BMC Infectious Diseases 2015 15:125
  28. Acute respiratory infections (ARIs) are common in children and mostly caused by viruses, but the significance of the detection of multiple viruses in ARIs is unclear. This study investigated 14 respiratory vir...

    Authors: Binglin Cui, Dangui Zhang, Hui Pan, Fan Zhang, Jeremy Farrar, Frieda Law, H Rogier van Doorn, Beiyan Wu and William Ba-Thein
    Citation: BMC Infectious Diseases 2015 15:124
  29. Pseudomonas aeruginosa is an important nosocomial pathogen, commonly causing infections in immunocompromised patients. The aim of this study was to examine the genetic relatedness of metallo-beta-lactamase (MBL) ...

    Authors: Mai Mahmoud Zafer, Mohamed Hamed Al-Agamy, Hadir Ahmed El-Mahallawy, Magdy Aly Amin and Seif El Din Ashour
    Citation: BMC Infectious Diseases 2015 15:122
  30. Measles cases may cluster in densely populated urban centers in sub-Saharan Africa as susceptible individuals share spatially dependent risk factors and may cluster among human immunodeficiency virus (HIV)-inf...

    Authors: Jessie Pinchoff, James Chipeta, Gibson Chitundu Banda, Samuel Miti, Timothy Shields, Frank Curriero and William John Moss
    Citation: BMC Infectious Diseases 2015 15:121
  31. Hepatitis B Virus (HBV) disproportionately affects new immigrants from endemic regions such as China. Untreated infections increase health risks for liver diseases including cancer. Yet most of those infected ...

    Authors: Grace X Ma, Guo Yolanda Zhang, Shumenghui Zhai, Xiang Ma, Yin Tan, Steven E Shive and Min Qi Wang
    Citation: BMC Infectious Diseases 2015 15:120
  32. Successful antiretroviral therapy (ART) has dramatically reduced mortality among HIV-infected children. However, there is growing concern about long-term effects associated to ART. The aim of this study was to...

    Authors: Daniel Blázquez, José Tomás Ramos-Amador, Talía Saínz, María José Mellado, Marta García-Ascaso, María Isabel De José, Pablo Rojo, María Luisa Navarro, María Ángeles Muñoz-Fernández, Jesús Saavedra, Miguel Angel Roa, Santiago Jiménez, José Beceiro, Luis Prieto, Milagros García Hortelano and María Isabel González-Tomé
    Citation: BMC Infectious Diseases 2015 15:119
  33. Although neonatal infections cause a significant proportion of deaths in the first week of life, little is known about the burden of neonatal disease originating from maternal infection or colonization globall...

    Authors: Grace J Chan, Anne CC Lee, Abdullah H Baqui, Jingwen Tan and Robert E Black
    Citation: BMC Infectious Diseases 2015 15:118
  34. Tuberculosis (TB) is a global public health concern. It is even more so as its incidence seems to be increasing in South Africa. The aim of this study was to describe and compare the tuberculosis infection con...

    Authors: Ntambwe Malangu and Michah Mngomezulu
    Citation: BMC Infectious Diseases 2015 15:117
  35. Staphylococcus aureus is one of the most common and lethal causes of bloodstream infection and the incidence is increasing. We carried out a prospective observational study of patients with Staphylococcus aureus ...

    Authors: Julie Paulsen, Arne Mehl, Åsa Askim, Erik Solligård, Bjørn Olav Åsvold and Jan Kristian Damås
    Citation: BMC Infectious Diseases 2015 15:116
  36. Women in sub-Saharan Africa are vulnerable to acquiring HIV infection and reproductive tract infections. Bacterial vaginosis (BV), a disruption of the vaginal microbiota, has been shown to be strongly associat...

    Authors: Vicky Jespers, Janneke van de Wijgert, Piet Cools, Rita Verhelst, Hans Verstraelen, Sinead Delany-Moretlwe, Mary Mwaura, Gilles F Ndayisaba, Kishor Mandaliya, Joris Menten, Liselotte Hardy and Tania Crucitti
    Citation: BMC Infectious Diseases 2015 15:115
  37. The use of recombinant viral vectors expressing T. gondii antigens is a safe and efficient approach to induce immune responses against the parasite, as well as a valuable tool for vaccine development. We have pre...

    Authors: Xiu-Zhen Li, Xiao-Hu Wang, Li-Jun Xia, Ya-Biao Weng, Jorge A Hernandez, Li-Qing Tu, Lu-Tao Li, Shou-Jun Li and Zi-Guo Yuan
    Citation: BMC Infectious Diseases 2015 15:114
  38. Streptococcus pyogenes (group A streptococcus; GAS) is an etiological agent for pharyngitis, pyoderma, and invasive infections in humans. Pharyngitis and pyoderma may lead to serious immune sequelae such as rheum...

    Authors: Mohan G Karmarkar, Gouri P Hule, Ainslie Cameron, Preeti R Mehta, Uday Khopkar, Niwrutti K Hase and Kadaba S Sriprakash
    Citation: BMC Infectious Diseases 2015 15:113
  39. Ethiopia, a high tuberculosis (TB) burden country, reports one of the highest incidence rates of extra-pulmonary TB dominated by cervical lymphadenitis (TBLN). Infection with Mycobacterium bovis has previously be...

    Authors: Stefan Berg, Esther Schelling, Elena Hailu, Rebuma Firdessa, Balako Gumi, Girume Erenso, Endalamaw Gadisa, Araya Mengistu, Meseret Habtamu, Jemal Hussein, Teklu Kiros, Shiferaw Bekele, Wondale Mekonnen, Yohannes Derese, Jakob Zinsstag, Gobena Ameni…
    Citation: BMC Infectious Diseases 2015 15:112
  40. Syphilis and HIV infections in pregnancy result in a number of adverse outcomes including neonatal death and vertical transmission. Ethiopia is a country where these infections are highly prevalent. However, d...

    Authors: Mengistu Endris, Tekalign Deressa, Yeshambel Belyhun and Feleke Moges
    Citation: BMC Infectious Diseases 2015 15:111
  41. Early warning and robust estimation of influenza burden are critical to inform hospital preparedness and operational, treatment, and vaccination policies. Methods to enhance influenza-like illness (ILI) survei...

    Authors: Lydia N Drumright, Simon DW Frost, Alex J Elliot, Mike Catchpole, Richard G Pebody, Mark Atkins, John Harrison, Penny Parker and Alison H Holmes
    Citation: BMC Infectious Diseases 2015 15:110
  42. Influenza H7N9 has become an endemic pathogen in China where circulating virus is found extensively in wild birds and domestic poultry. Two epidemic waves of Human H7N9 infections have taken place in Eastern a...

    Authors: Amber Farooqui, Alberto J Leon, Linxi Huang, Suwu Wu, Yingmu Cai, Pengzhou Lin, Weihong Chen, Xibin Fang, Tiansheng Zeng, Yisu Liu, Li Zhang, Ting Su, Weibin Chen, Elodie Ghedin, Huachen Zhu, Yi Guan…
    Citation: BMC Infectious Diseases 2015 15:109
  43. Candida albicans remains as the first cause of nosocomial fungal infections in hospitals worldwide and its susceptibility pattern should be better described in our tertiary care hospitals.

    Authors: Giovanni Rodríguez-Leguizamón, Alessandro Fiori, Katrien Lagrou, María Antonia Gaona, Milciades Ibáñez, Manuel Alfonso Patarroyo, Patrick Van Dijck and Arley Gómez-López
    Citation: BMC Infectious Diseases 2015 15:108
  44. While enterococci resistant to multiple antimicrobials are spreading in hospitals worldwide, causing urinary tract, wound and bloodstream infections, there is little published data on these infections from Afr...

    Authors: Håvard Aamodt, Stein Christian Mohn, Samuel Maselle, Karim P Manji, Rob Willems, Roland Jureen, Nina Langeland and Bjørn Blomberg
    Citation: BMC Infectious Diseases 2015 15:107
  45. Literature on the epidemiology of herpes zoster (HZ) in cancer patients is sparse and does not include the elderly. The objectives of this study were to determine the incidence of HZ and related complications ...

    Authors: Mihran A Yenikomshian, Adrienne P Guignard, François Haguinet, Ann S LaCasce, Arthur T Skarin, Alex Trahey, Paul Karner and Mei Sheng Duh
    Citation: BMC Infectious Diseases 2015 15:106
  46. Predictive models to identify unknown methicillin-resistant Staphylococcus aureus (MRSA) carriage on admission may optimise targeted MRSA screening and efficient use of resources. However, common approaches to mo...

    Authors: Andie S Lee, Angelo Pan, Stephan Harbarth, Andrea Patroni, Annie Chalfine, George L Daikos, Silvia Garilli, José Antonio Martínez and Ben S Cooper
    Citation: BMC Infectious Diseases 2015 15:105
  47. Cholera, an infectious disease caused by Vibrio cholerae, is a major public health problem and is a particularly burden in developing countries including Nepal. Although the recent worldwide outbreaks of cholera ...

    Authors: Upendra Thapa Shrestha, Nabaraj Adhikari, Rojina Maharjan, Megha R Banjara, Komal R Rijal, Shital R Basnyat and Vishwanath P Agrawal
    Citation: BMC Infectious Diseases 2015 15:104
  48. Pneumocystis pneumonia (PCP) may develop as a clinical manifestation of nosocomial pneumonia by means of either reactivation of resident P. jirovecii or de novo infection. However, there have been no studies desc...

    Authors: Tark Kim, Sang-Oh Lee, Hyo-Lim Hong, Ju Young Lee, Sung-Han Kim, Sang-Ho Choi, Mi-Na Kim, Yang Soo Kim, Jun Hee Woo and Heungsup Sung
    Citation: BMC Infectious Diseases 2015 15:102
  49. The present study aims to investigate the potential mechanism of linezolid-resistant Staphylococcus capitis (LRSC) isolates collected from our hospital.

    Authors: Wanqing Zhou, Dongmei Niu, Xiaoli Cao, Mingzhe Ning, Zhifeng Zhang, Han Shen and Kui Zhang
    Citation: BMC Infectious Diseases 2015 15:97

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