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  1. Dengue has not reached an endemic status in Taiwan; nevertheless, we have implemented a fever screening program at airports for the early detection of febrile passengers with a dengue infection. This study is ...

    Authors: Mei-Mei Kuan and Feng-Yee Chang
    Citation: BMC Infectious Diseases 2012 12:182
    Content type: Research article Published on:

  2. In several European Countries, by the end of 2012, CLSI guidelines will be replaced by EUCAST. We compared antimicrobial susceptibility results of a large number of respiratory pathogens using both EUCAST and ...

    Authors: Anna Marchese, Susanna Esposito, Ramona Barbieri, Matteo Bassetti and Eugenio Debbia
    Citation: BMC Infectious Diseases 2012 12:181
    Content type: Correspondence Published on:

  3. Combined antiretroviral therapy (cART) in the treatment of HIV-1 infection has been associated with complications, including lipodystrophy, hyperlipidaemia, insulin resistance (IR) and diabetes.

    Authors: Paula Freitas, Davide Carvalho, Ana Cristina Santos, Joana Mesquita, Maria João Matos, Antonio Jose Madureira, Esteban Martinez, António Sarmento and José Luís Medina
    Citation: BMC Infectious Diseases 2012 12:180
    Content type: Research article Published on:

  4. Although dual-boosted protease inhibitors regimen is not recommended in children with HIV infection, such a strategy could be useful in subjects with a complex resistance profile. This study was aimed at asses...

    Authors: Stefano Rusconi, Vania Giacomet, Chiara Mameli, Alessandra Viganò, Ottavia Viganò, Fulvio Adorni, Massimo Galli and Gian Vincenzo Zuccotti
    Citation: BMC Infectious Diseases 2012 12:179
    Content type: Research article Published on:

  5. Coxsackievirus B3 is an important infectious agent of viral myocarditis, pancreatitis and aseptic meningitis, but there are no specific antiviral therapeutic reagents in clinical use. RNA interference-based te...

    Authors: Hailan Yao, Yangde Zhang, Feng He, Caihong Wang, Zonghui Xiao, Jizhen Zou, Fang Wang and Zhewei Liu
    Citation: BMC Infectious Diseases 2012 12:177
    Content type: Research article Published on:

  6. Nosocomial infections caused by Pseudomonas aeruginosa presenting resistance to beta-lactam drugs are one of the most challenging targets for antimicrobial therapy, leading to substantial increase in mortality ra...

    Authors: Milena Polotto, Tiago Casella, Maria Gabriela de Lucca Oliveira, Fernando G Rúbio, Mauricio L Nogueira, Margarete TG de Almeida and Mara CL Nogueira
    Citation: BMC Infectious Diseases 2012 12:176
    Content type: Research article Published on:

  7. Analysis of US claims data from April 2010 to June 2011 estimated that 39% of the 13-valent pneumococcal conjugate vaccine (PCV13) catch-up eligible cohort would ever receive the catch-up vaccination; a previo...

    Authors: David R Strutton, Raymond A Farkouh, Jaime L Rubin, Lisa J McGarry, Paul M Loiacono, Keith P Klugman, Steven I Pelton, Kristen E Gilmore and Milton C Weinstein
    Citation: BMC Infectious Diseases 2012 12:175
    Content type: Research article Published on:

  8. The near-patient environment is often heavily contaminated, yet the decontamination of near-patient surfaces and equipment is often poor. The Nanoclave Cabinet produces large amounts of ultraviolet-C (UV-C) ra...

    Authors: Ginny Moore, Shanom Ali, Elaine A Cloutman-Green, Christina R Bradley, Martyn AC Wilkinson, John C Hartley, Adam P Fraise and A Peter R Wilson
    Citation: BMC Infectious Diseases 2012 12:174
    Content type: Research article Published on:

  10. Although checking specimen quality upon sputum collection for acid-fast smear of suspected tuberculosis (TB) cases is recommended, this procedure is based on expert opinion. The purpose of this study was to el...

    Authors: Soon Ho Yoon, Nyoung Keun Lee and Jae Joon Yim
    Citation: BMC Infectious Diseases 2012 12:172
    Content type: Research article Published on:

  11. Eperythrozoonosis is an important animal health problem worldwide, it not only has a major impact on the economic viability, but also makes a significant impact on public health issues. The present systemic re...

    Authors: De-Sheng Huang, Peng Guan, Wei Wu, Tie-Feng Shen, He-Ling Liu, Shuang Cao and Hao Zhou
    Citation: BMC Infectious Diseases 2012 12:171
    Content type: Research article Published on:

  12. It is not fully understood why healthcare decision-makers of developing countries often give low priority to infection control and why they are unable to implement international guidelines. This study aimed to...

    Authors: Bat-Erdene Ider, Jon Adams, Anthony Morton, Michael Whitby and Archie Clements
    Citation: BMC Infectious Diseases 2012 12:170
    Content type: Research article Published on:

  13. Diagnosis and treatment of latent tuberculosis infection (LTBI) is the most effective strategy to control tuberculosis (TB) among patients with HIV infection. The tuberculin skin test (TST) was the only availa...

    Authors: José M Ramos, Catalina Robledano, Mar Masiá, Sofia Belda, Sergio Padilla, Juan C Rodríguez and Félix Gutierrez
    Citation: BMC Infectious Diseases 2012 12:169
    Content type: Research article Published on:

  14. For antiretroviral therapy (ART) naive human immunodeficiency virus (HIV) infected adults suffering from tuberculosis (TB), there is uncertainty about the optimal time to initiate highly active antiretroviral ...

    Authors: Sanjeev Sinha, Rahul C Shekhar, Gurjeet Singh, Nipam Shah, Hafiz Ahmad, Narendra Kumar, Surendra K Sharma, JC Samantaray, Sanjai Ranjan, Meera Ekka, Vishnu Sreenivas and Ronald T Mitsuyasu
    Citation: BMC Infectious Diseases 2012 12:168
    Content type: Research article Published on:

  15. Our aim was to investigate the aortic distensibility (AD) of the ascending aorta and carotid artery intima-media thickness (c-IMT) in HIV-infected patients compared to healthy controls.

    Authors: Alexandra Zormpala, Nikolaos V Sipsas, Ioannis Moyssakis, Sarah P Georgiadou, Maria N Gamaletsou, Athanasios N Kontos, Panayiotis D Ziakas and Theodore Kordossis
    Citation: BMC Infectious Diseases 2012 12:167
    Content type: Research article Published on:

  16. Although cervical cancer is the leading cancer in Cambodia, most women receive no routine screening for cervical cancer and few treatment options exist. Moreover, nothing is known regarding the prevalence of c...

    Authors: Marie-Claude Couture, Kimberly Page, Ellen S Stein, Neth Sansothy, Keo Sichan, John Kaldor, Jennifer L Evans, Lisa Maher and Joel Palefsky
    Citation: BMC Infectious Diseases 2012 12:166
    Content type: Research article Published on:

  17. Due to the association between diabetes and pulmonary tuberculosis (TB), diabetes may threaten the control of TB. In a prospective cohort study nested in a nutrition trial, we investigated the role of diabetes...

    Authors: Daniel Faurholt-Jepsen, Nyagosya Range, George Praygod, Jeremiah Kidola, Maria Faurholt-Jepsen, Martine Grosos Aabye, John Changalucha, Dirk Lund Christensen, Torben Martinussen, Henrik Krarup, Daniel Rinse Witte, Åse Bengård Andersen and Henrik Friis
    Citation: BMC Infectious Diseases 2012 12:165
    Content type: Research article Published on:

  18. Enteric fever is a major public health problem, causing an estimated 21million new cases and 216,000 or more deaths every year. Current diagnosis of the disease is inadequate. Blood culture only identifies 45 ...

    Authors: Liqing Zhou and Andrew J Pollard
    Citation: BMC Infectious Diseases 2012 12:164
    Content type: Research article Published on:

  19. A broad spectrum of pathogens is causative for respiratory tract infections, but symptoms are mostly similar. Therefore, the identification of the causative viruses and bacteria is only feasible using multiple...

    Authors: Mareike Dabisch-Ruthe, Tanja Vollmer, Ortwin Adams, Cornelius Knabbe and Jens Dreier
    Citation: BMC Infectious Diseases 2012 12:163
    Content type: Research article Published on:

  20. Flexibility of vaccination schedule and lower antigen content can facilitate pandemic vaccine coverage. We assessed the immune response and safety of AS03-adjuvanted A/California/7/2009 H1N1 pandemic vaccine c...

    Authors: Xavier Duval, Adrian Caplanusi, Henri Laurichesse, Dominique Deplanque, Pierre Loulergue, Tejaswini Vaman, Odile Launay and Paul Gillard
    Citation: BMC Infectious Diseases 2012 12:162
    Content type: Research article Published on:

  21. Fusobacterium species are uncommon causes of osteomyelitis. These organisms are normal flora of the oral cavity. Therefore, they mostly cause osteomyelitis of the head and neck. Hematogenous osteomyelitis at dis...

    Authors: Min Ji Lee, Young Eun Ha, Hye Yon Park, Jun Hee Lee, Yoon Jung Lee, Ki Sun Sung, Cheol-In Kang, Doo Ryeon Chung, Jae-Hoon Song and Kyong Ran Peck
    Citation: BMC Infectious Diseases 2012 12:161
    Content type: Case report Published on:

  22. Despite screening blood donations with advanced technologies and improved donor screening, the risk of transfusion-transmitted infections persists. This risk is mainly due to blood donations collected during t...

    Authors: Moon Jung Kim, Quehn Park, Hyuk Ki Min and Hyun Ok Kim
    Citation: BMC Infectious Diseases 2012 12:160
    Content type: Research article Published on:

  23. Switch therapy is a management approach combining early discontinuation of intravenous (IV) antibiotics, switch to oral antibiotics, and early hospital discharge. This analysis compares switch therapy using ti...

    Authors: Julio A Ramirez, Angel C Cooper, Timothy Wiemken, David Gardiner and Timothy Babinchak
    Citation: BMC Infectious Diseases 2012 12:159
    Content type: Research article Published on:

  24. Urinary tract infection (UTI) is common in children, and may cause serious illness and recurrent symptoms. However, obtaining a urine sample from young children in primary care is challenging and not feasible ...

    Authors: Harriet Downing, Emma Thomas-Jones, Micaela Gal, Cherry-Ann Waldron, Jonathan Sterne, William Hollingworth, Kerenza Hood, Brendan Delaney, Paul Little, Robin Howe, Mandy Wootton, Alastair Macgowan, Christopher C Butler and Alastair D Hay
    Citation: BMC Infectious Diseases 2012 12:158
    Content type: Study protocol Published on:

  25. The purpose of this study was to explore the diagnostic value of soluble triggering receptor expressed on myeloid cells 1 (sTREM-1), procalcitonin (PCT), and C-reactive protein (CRP) serum levels for different...

    Authors: Longxiang Su, Bingchao Han, Changting Liu, Liling Liang, Zhaoxu Jiang, Jie Deng, Peng Yan, Yanhong Jia, Dan Feng and Lixin Xie
    Citation: BMC Infectious Diseases 2012 12:157
    Content type: Research article Published on:

  26. Dengue fever is an endemic illness in the tropics with early and post infectious complications affecting multiple systems. Though neurological sequelae including mononeuropathy, encephalopathy, transverse myel...

    Authors: Mitrakrishnan C Shivanthan, Eranda C Ratnayake, Bandula C Wijesiriwardena, Kalum C Somaratna and Lakmal KGK Gamagedara
    Citation: BMC Infectious Diseases 2012 12:156
    Content type: Case report Published on:

  27. The worldwide increase in antibiotic resistant bacteria is of great concern. One of the main causes is antibiotic use which is likely to be high but is poorly described in India. The aim was to analyze and com...

    Authors: Megha Sharma, Bo Eriksson, Gaetano Marrone, Suryaprakash Dhaneria and Cecilia Stålsby Lundborg
    Citation: BMC Infectious Diseases 2012 12:155
    Content type: Research article Published on:

  28. Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of complicated skin and skin structure infections (cSSSI). Patients with MRSA require different empiric treatment than those with non-MRSA in...

    Authors: Marya D Zilberberg, Paresh Chaudhari, Brian H Nathanson, Rebecca S Campbell, Matthew F Emons, Suzanne Fiske, Harlen D Hays and Andrew F Shorr
    Citation: BMC Infectious Diseases 2012 12:154
    Content type: Research article Published on:

  29. Optimal antibiotic treatment strategies of Haemophilus infections are still needed. Therefore, 30-day case fatality rate (CFR) of Haemophilus bacteremia and efficacy of various antibiotic treatment regimes were s...

    Authors: Sara Thønnings and Christian Østergaard
    Citation: BMC Infectious Diseases 2012 12:153
    Content type: Research article Published on:

  30. The clinical effects of varying pharmacokinetic exposures of antibiotics (antibacterials and antifungals) on outcome in infected critically ill patients are poorly described. A large-scale multi-centre study (...

    Authors: Jason A Roberts, Jan J De Waele, George Dimopoulos, Despoina Koulenti, Claude Martin, Philippe Montravers, Jordi Rello, Andrew Rhodes, Therese Starr, Steven C Wallis and Jeffrey Lipman
    Citation: BMC Infectious Diseases 2012 12:152
    Content type: Study protocol Published on:

  31. Pediatric patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) often receive intravenous liposomal amphotericin B (L-AmB) as antifungal prophylaxis. There are no guidelines for antifun...

    Authors: Michaela Döring, Ulrike Hartmann, Annika Erbacher, Peter Lang, Rupert Handgretinger and Ingo Müller
    Citation: BMC Infectious Diseases 2012 12:151
    Content type: Research article Published on:

  32. The number of diagnosed cases of Chlamydia trachomatis infection has been increasing in the past years in Norway although the testing rate has been relatively stable. The aim of this study was to measure the prev...

    Authors: Hilde Kløvstad, Andrej Grjibovski and Preben Aavitsland
    Citation: BMC Infectious Diseases 2012 12:150
    Content type: Research article Published on:

  33. The prevalence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli has been increased not only in the hospital but also in the community worldwide. This study was aimed to characterize ESBL- produc...

    Authors: Sun Hee Park, Ji-Hyun Byun, Su-Mi Choi, Dong-Gun Lee, Si-Hyun Kim, Jae-Cheol Kwon, Chulmin Park, Jung-Hyun Choi and Jin-Hong Yoo
    Citation: BMC Infectious Diseases 2012 12:149
    Content type: Research article Published on:

  35. Changes in CD4 cell counts are poorly documented in individuals with low or moderate-level viremia while on antiretroviral treatment (ART) in resource-limited settings. We assessed the impact of on-going HIV-R...

    Authors: Alexandra Calmy, Eric Balestre, Fabrice Bonnet, Andrew Boulle, Eduardo Sprinz, Robin Wood, Eric Delaporte, Eugène Messou, James McIntyre, Kamal Marhoum El Filali, Mauro Schechter, N Kumarasamy, David Bangsberg, Patrick McPhail, Stefaan Van Der Borght, Carlos Zala…
    Citation: BMC Infectious Diseases 2012 12:147
    Content type: Research article Published on:

  36. Uncomplicated urinary tract infections (UTI) are usually treated with antibiotics as recommended by primary care guidelines. Antibiotic treatment supports clinical cure in individual patients but also leads to...

    Authors: Ildikó Gágyor, Eva Hummers-Pradier, Michael M Kochen, Guido Schmiemann, Karl Wegscheider and Jutta Bleidorn
    Citation: BMC Infectious Diseases 2012 12:146
    Content type: Study protocol Published on:

  37. Human papillomavirus (HPV) is a sexually transmitted infection that may lead to development of precancerous and cancerous lesions of the cervix. The aim of the current study was to investigate socio-demographi...

    Authors: Esther Roura, Thomas Iftner, José Antonio Vidart, Susanne Krüger Kjaer, F Xavier Bosch, Nubia Muñoz, Santiago Palacios, Maria San Martin Rodriguez, Carmen Morillo, Laurence Serradell, Laurence Torcel-Pagnon, Javier Cortes and Xavier Castellsagué
    Citation: BMC Infectious Diseases 2012 12:145
    Content type: Research article Published on:

  38. The purpose of this study was to investigate mediators of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis (CNPA), a locally, destructive process of the lung due to inv...

    Authors: Ernst Kristian Rødland, Thor Ueland, Stine Bjørnsen, Ellen Lund Sagen, Christen Peder Dahl, Anne Naalsund, Tom Eirik Mollnes, Frank R Brosstad, Fredrik Müller, Pål Aukrust and Stig S Frøland
    Citation: BMC Infectious Diseases 2012 12:144
    Content type: Research article Published on:

  39. Over the years, reports implicate improper anti-malarial use as a major contributor of morbidity and mortality amongst millions of residents in malaria endemic areas, Kenya included. However, there are limited...

    Authors: Elizabeth O Onyango, George Ayodo, Carren A Watsierah, Tom Were, Wilson Okumu, Samuel B Anyona, Evans Raballah, John M Okoth, Sussy Gumo, George O Orinda and Collins Ouma
    Citation: BMC Infectious Diseases 2012 12:143
    Content type: Research article Published on:

  40. Hepatitis E virus (HEV) has emerged as an important cause of epidemic and sporadic acute viral hepatitis worldwide. This study investigated the seroprevalence of anti-HEV in a Korean population and compared th...

    Authors: Hyun Kyung Park, Sook-Hyang Jeong, Jin-Wook Kim, Byung-Hyun Woo, Dong Ho Lee, Hyun Young Kim and Soyeon Ahn
    Citation: BMC Infectious Diseases 2012 12:142
    Content type: Research article Published on:

  41. This study was aimed to investigate the diagnostic value of fiberoptic bronchoscopy (FOB) with chest high-resolution computed tomography (HRCT) for the rapid diagnosis of active pulmonary tuberculosis (PTB) in...

    Authors: Jung Ar Shin, Yoon Soo Chang, Tae Hoon Kim, Hyung Jung Kim, Chul Min Ahn and Min Kwang Byun
    Citation: BMC Infectious Diseases 2012 12:141
    Content type: Research article Published on:

  42. In the Netherlands, infection with varicella-zoster virus (VZV) is considered a benign common childhood illness and routine vaccination against VZV is not done. In 1995 it was estimated that 98-100% of the adu...

    Authors: Gini GC van Rijckevorsel, Marjolein Damen, Gerard J Sonder, Maarten F Schim van der Loeff and Anneke van den Hoek
    Citation: BMC Infectious Diseases 2012 12:140
    Content type: Research article Published on:

  43. Asplenic individuals are susceptible for overwhelming infection with Streptococcus pneumoniae, carrying a high mortality. Although Toll-like receptor (TLR)-2 is considered the major receptor for Gram-positive bac...

    Authors: Adriana J J Lammers, Alexander P N A de Porto, Onno J de Boer, Sandrine Florquin and Tom van der Poll
    Citation: BMC Infectious Diseases 2012 12:139
    Content type: Research article Published on:

  44. Pertussis is a reported vaccine-preventable respiratory disease in China. Because the routine laboratory methods for diagnosis are not in use, the reported cases are mainly in infants with classical paroxysmal...

    Authors: Qi Zhang, Huizhen Zheng, Meizhen Liu, Ke Han, Jun Shu, Chenggang Wu, Ning Xu, Qiushui He and Huiming Luo
    Citation: BMC Infectious Diseases 2012 12:138
    Content type: Research article Published on:

  45. Human papillomavirus (HPV) seroprevalence data have not previously been reported for different geographical regions of China. This study investigated the cross-sectional seroprevalence of antibodies to HPV 6, ...

    Authors: Jia Ji, Hai-Kui Sun, Jennifer S Smith, He Wang, Mark T Esser, Shangying Hu, Robert G Pretorius, Wen Chen, Jerome L Belinson and You-Lin Qiao
    Citation: BMC Infectious Diseases 2012 12:137
    Content type: Research article Published on:

  46. The epidemic of encephalitis lethargica (EL), called classical EL, was rampant throughout the world during 1917–1926, affecting half a million persons. The acute phase was lethal for many victims. Post-encepha...

    Authors: Robert R Dourmashkin, Glynis Dunn, Victor Castano and Sherman A McCall
    Citation: BMC Infectious Diseases 2012 12:136
    Content type: Research article Published on:

  47. The vast majority of research in the area of community-acquired pneumonia (CAP) has been based on patients admitted to hospital. And yet, the majority of patients with CAP are treated on an ambulatory basis as...

    Authors: Dean T Eurich, Sumit R Majumdar and Thomas J Marrie
    Citation: BMC Infectious Diseases 2012 12:135
    Content type: Research article Published on:

  48. The etiologic profile of community-acquired pneumonia (CAP) for each age group could be similar among inpatients and outpatients. This fact brings up the link between etiology of CAP and its clinical evolution...

    Authors: Alberto Capelastegui, Pedro P España, Amaia Bilbao, Julio Gamazo, Federico Medel, Juan Salgado, Iñaki Gorostiaga, Maria Jose Lopez de Goicoechea, Inmaculada Gorordo, Cristobal Esteban, Lander Altube and Jose M Quintana
    Citation: BMC Infectious Diseases 2012 12:134
    Content type: Research article Published on:

  49. Daptomycin is a rapidly bactericidal agent with broad coverage against Gram-positive organisms, including Staphylococcus aureus, the most frequent cause of osteomyelitis. The objective of this study was to descri...

    Authors: Jason C Gallagher, Jennifer A Huntington, Darren Culshaw, Scott A McConnell, Minjung Yoon and Elie Berbari
    Citation: BMC Infectious Diseases 2012 12:133
    Content type: Research article Published on:

  50. Dengue fever has been a major public health concern in China since it re-emerged in Guangdong province in 1978. This study aimed to explore spatiotemporal characteristics of dengue fever cases for both indigen...

    Authors: Zhongjie Li, Wenwu Yin, Archie Clements, Gail Williams, Shengjie Lai, Hang Zhou, Dan Zhao, Yansha Guo, Yonghui Zhang, Jinfeng Wang, Wenbiao Hu and Weizhong Yang
    Citation: BMC Infectious Diseases 2012 12:132
    Content type: Research article Published on:

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