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  1. Few studies have assessed the time to blood culture positivity as a predictor of clinical outcome in fungal bloodstream infections (BSIs). The purpose of this study was to evaluate the time to positivity (TTP)...

    Authors: Cintia Zoya Nunes, Alexandre R Marra, Michael B Edmond, Elivane da Silva Victor and Carlos Alberto Pires Pereira
    Citation: BMC Infectious Diseases 2013 13:486
  2. High prevalence rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) have been reported in Aboriginal people in remote and regional areas of Australia for well over two decades, and repeat positivit...

    Authors: Rebecca J Guy, Lisa Natoli, James Ward, Louise Causer, Belinda Hengel, David Whiley, Sepehr N Tabrizi, Basil Donovan, Christopher K Fairley, Steven B Badman, Annie Tangey, Handan Wand, Mark Shephard, David G Regan, David Wilson, David Anderson…
    Citation: BMC Infectious Diseases 2013 13:485
  3. Previous studies have shown that Mycobacterium tuberculosis (MTB) Uganda family, a sub-lineage of the MTB Lineage 4, is the main cause of tuberculosis (TB) in Uganda. Using a well characterized patient population...

    Authors: Eddie M Wampande, Ezekiel Mupere, Sara M Debanne, Benon B Asiimwe, Mary Nsereko, Harriet Mayanja, Kathleen Eisenach, Gilla Kaplan, Henry W Boom, Sebastien Gagneux and Moses L Joloba
    Citation: BMC Infectious Diseases 2013 13:484
  4. A high prevalence of bacterial nasopharyngeal co-infections has been reported in children, however, such data is limited in adults. We examined the interaction of Haemophilus influenzae, Staphylococcus aureus and...

    Authors: Tinevimbo Shiri, Marta C Nunes, Peter V Adrian, Nadia Van Niekerk, Keith P Klugman and Shabir A Madhi
    Citation: BMC Infectious Diseases 2013 13:483
  5. Administration of rifampicin along with nevirapine reduces the plasma concentration of nevirapine in human immunodeficiency virus positive individuals with concomitant tuberculosis (HIV-TB patients). Nevirapin...

    Authors: Sanjeev Sinha, Puroshottam Raghunandan, Rahul Chandrashekhar, Surendra K Sharma, Sanjiv Kumar, Sahajal Dhooria, Meera Ekka, Thirumurthy Velpandian, Sanjay Ranjan, Hafeez Ahmad, Jyotish Chandra Samantaray, Srinivasaraghavan Venkatesh, Bharat Bhushan Rewari, Nawaid Hussain Khan and Ravindra Mohan Pandey
    Citation: BMC Infectious Diseases 2013 13:482
  6. Sexually transmitted diseases and most notably syphilis-infections are rising amongst men who have sex with men. In HIV-co-infected patients, an accelerated clinical course of syphilis neurological involvement...

    Authors: Christoph D Spinner, Sebastian Noe, Christiane Schwerdtfeger, Antonia Todorova, Jochen Gaa, Roland M Schmid, Dirk H Busch and Michael Neuenhahn
    Citation: BMC Infectious Diseases 2013 13:481
  7. Bacterial vaginosis (BV) is a common condition, although its aetiology remains unexplained. The aim of this study was to analyse the composition of vaginal microbiota in women from Greenland to provide a quant...

    Authors: Raluca Datcu, Dionne Gesink, Gert Mulvad, Ruth Montgomery-Andersen, Elisabeth Rink, Anders Koch, Peter Ahrens and Jørgen Skov Jensen
    Citation: BMC Infectious Diseases 2013 13:480
  8. Mycobacteirum wolinskyi is a member of the Mycobacterium smegmatis group, which is less frequently found in clinical settings than other nontuberculous mycobacterium (NTM) species. However, its clinical signific...

    Authors: Seung Jin Yoo, Keun Hwa Lee, Sung-No Jung and Sang Taek Heo
    Citation: BMC Infectious Diseases 2013 13:479
  9. Drug-resistant tuberculosis (TB), including resistance to both rifampicin (RIF) and isoniazid (INH) referred to as multidrug-resistant tuberculosis (MDR-TB), has become an increasing global threat in recent ye...

    Authors: Eunjin Cho, Isdore Chola Shamputa, Hyun-Kyung Kwak, Jiim Lee, Myungsun Lee, Soohee Hwang, Doosoo Jeon, Cheon Tae Kim, Sangnae Cho, Laura E Via, Clifton E Barry 3rd and Jong Seok Lee
    Citation: BMC Infectious Diseases 2013 13:478
  10. Antibiotic resistance is a major global public health concern, particularly in settings where few treatment options are available. Limited research has been done on antibiotic resistance in Escherichia coli of In...

    Authors: Pragya Shakya, Peter Barrett, Vishal Diwan, Yogyata Marothi, Harshada Shah, Neeraj Chhari, Ashok J Tamhankar, Ashish Pathak and Cecilia Stålsby Lundborg
    Citation: BMC Infectious Diseases 2013 13:477
  11. Antiretroviral therapy (ART) scale-up in resource-limited countries, with limited capacity for CD4 and HIV viral load monitoring, presents a unique challenge. We determined the effectiveness of first-line ART ...

    Authors: Oliver Barry, Jonathan Powell, Lorna Renner, Evelyn Y Bonney, Meghan Prin, William Ampofo, Jonas Kusah, Bamenla Goka, Kwamena WC Sagoe, Veronika Shabanova and Elijah Paintsil
    Citation: BMC Infectious Diseases 2013 13:476
  12. We investigated the immune response to serogroup 6 with the opsonophagocytic killing assay (OPKA) in children aged 12–23 months of age after immunization with the 7-valent pneumococcal conjugate vaccine (PCV7)...

    Authors: Hyunju Lee, Jung Hwa Cha, Moon H Nahm, Robert L Burton and Kyung-Hyo Kim
    Citation: BMC Infectious Diseases 2013 13:474
  13. The aim of our work was to evaluate the potential impact of the European policy of testing for HIV all individuals presenting with an indicator disease, to prevent late diagnosis of HIV. We report on a retrosp...

    Authors: Paola Scognamiglio, Giacomina Chiaradia, Gabriella De Carli, Massimo Giuliani, Claudio Maria Mastroianni, Stefano Aviani Barbacci, Anna Rita Buonomini, Susanna Grisetti, Alessandro Sampaolesi, Angela Corpolongo, Nicoletta Orchi, Vincenzo Puro, Giuseppe Ippolito and Enrico Girardi
    Citation: BMC Infectious Diseases 2013 13:473
  14. Some manufacturers recommend using 1.1 mL per application of alcohol-based handrubs for effective hand disinfection. However, whether this volume is sufficient to cover both hands, as recommended by the World ...

    Authors: Günter Kampf, Sigunde Ruselack, Sven Eggerstedt, Nicolas Nowak and Muhammad Bashir
    Citation: BMC Infectious Diseases 2013 13:472
  15. Non-AIDS defining cancers (NADC) are an important cause of morbidity and mortality in HIV-positive individuals. Using data from a large international cohort of HIV-positive individuals, we described the incide...

    Authors: Signe W Worm, Mark Bower, Peter Reiss, Fabrice Bonnet, Matthew Law, Gerd Fätkenheuer, Antonella d’Arminio Monforte, Donald I Abrams, Andrew Grulich, Eric Fontas, Ole Kirk, Hansjakob Furrer, Stephane De Wit, Andrew Phillips, Jens D Lundgren and Caroline A Sabin
    Citation: BMC Infectious Diseases 2013 13:471
  16. In Italy the prevalence of genital warts in women (15–64 years) is approximately 0.6% with an incidence of 0.4% per year. Treatments for GW are usually long, with moderate success and high costs. The aim of th...

    Authors: Maria Michela Gianino, Sergio Delmonte, Emanuela Lovato, Morena Martinese, Sabrina Rondoletti, Maria Grazia Bernengo and Carla Maria Zotti
    Citation: BMC Infectious Diseases 2013 13:470
  17. The Erythrocyte Binding Antigen (EBA) 175 has been considered as one of the most important Plasmodium falciparum (P. falciparum) merozoite ligands that mediate invasion of the erythrocytes through their sialated ...

    Authors: Ahmed AM Adam, Ahmed AA Amine, Dina A Hassan, Waleed H Omer, Bakri Y Nour, Arulanantham Zechariah Jebakumar, Muntaser E Ibrahim, Nasreldin H Abdulhadi and Hiba S Mohamed
    Citation: BMC Infectious Diseases 2013 13:469
  18. Despite the latest World Health Organization guidelines advocating daily therapy in HIV-TB co-infected individuals, there are few recent studies comparing outcomes of thrice-weekly anti-tuberculosis treatment ...

    Authors: Richa Vashishtha, Krishna Mohan, Bhagteshwar Singh, Satish K Devarapu, Vishnubhatla Sreenivas, Sanjay Ranjan, Deepak Gupta, Sanjeev Sinha and Surendra K Sharma
    Citation: BMC Infectious Diseases 2013 13:468
  19. Differences in the susceptibility of Candida species to antifungal drugs make identification to the species level important for clinical management of candidemia. Molecular tests are not yet standardized or avail...

    Authors: Hemílio Xafranski, Analy SA Melo, Antonia M Machado, Marcelo RS Briones and Arnaldo L Colombo
    Citation: BMC Infectious Diseases 2013 13:467
  20. Klebsiella pneumoniae strains expressing ESBLs are a predominant cause of hospital acquired infections. Here we describe the molecular epidemiology of these isolates in a tertiary hospital in Tanzania, as potent...

    Authors: Stephen E Mshana, Torsten Hain, Eugen Domann, Eligius F Lyamuya, Trinad Chakraborty and Can Imirzalioglu
    Citation: BMC Infectious Diseases 2013 13:466
  21. Parvovirus B19 can cause petechial rashes in the acute phase of illness as well as erythema infectiosum (fifth disease) during convalescence. This petechial rash is often called “gloves and socks” syndrome bec...

    Authors: Masato Takeuchi, Ryosuke Shiozawa, Mayumi Hangai, Junko Takita and Sachiko Kitanaka
    Citation: BMC Infectious Diseases 2013 13:465
  22. Penicilliosis marneffei is increasingly observed in individuals without HIV infection. This study aimed to compare the clinical and laboratory features among HIV infected and uninfected individuals with penici...

    Authors: Rathakarn Kawila, Romanee Chaiwarith and Khuanchai Supparatpinyo
    Citation: BMC Infectious Diseases 2013 13:464
  23. Epidemiologic data of Herpes Zoster (HZ) disease in Spain are scarce. The objective of this study was to assess the epidemiology of HZ in the Valencian Community (Spain), using outpatient and hospital electron...

    Authors: Nuria Morant-Talamante, Javier Diez-Domingo, Sergio Martínez-Úbeda, Joan Puig-Barberá, Sara Alemán-Sánchez and Lina Pérez-Breva
    Citation: BMC Infectious Diseases 2013 13:463
  24. Human papillomavirus (HPV) is one of the most common sexually-transmitted pathogens. A number of studies in the literature have estimated the burden of HPV-related diseases by collecting data at primary care l...

    Authors: Vincenzo Baldo, Silvia Cocchio, Alessandra Buja, Tatjana Baldovin, Patrizia Furlan, Chiara Bertoncello and Mario Saia
    Citation: BMC Infectious Diseases 2013 13:462
  25. Children make up a significant proportion of the global tuberculosis (TB) caseload, and experience considerable TB-related morbidity and mortality. Unfortunately, it is not easy to diagnose TB in the first yea...

    Authors: Susanna Esposito, Alberto Giannini, Pietro Biondetti, Nicola Bonelli, Mario Nosotti, Samantha Bosis, Edoardo Calderini and Nicola Principi
    Citation: BMC Infectious Diseases 2013 13:461
  26. The tuberculin skin test (TST) is used to test for latent tuberculosis (TB) infection and support the diagnosis of active TB. However, little is known about the relationship between the TST result and the clin...

    Authors: Sara C Auld, Eleanor S Click, Charles M Heilig, Roque Miramontes, Kevin P Cain, Gregory P Bisson and William R Mac Kenzie
    Citation: BMC Infectious Diseases 2013 13:460
  27. Clostridium difficile infection (CDI) has increased to epidemic proportions in recent years. The carriage of C. difficile among healthy adults and hospital inpatients has been established. We sought to determine...

    Authors: N Deborah Friedman, James Pollard, Douglas Stupart, Daniel R Knight, Masoomeh Khajehnoori, Elise K Davey, Louise Parry and Thomas V Riley
    Citation: BMC Infectious Diseases 2013 13:459
  28. Hepatitis B e Antigen (HBeAg)-negative chronic hepatitis B (CHB) patients have an active liver disease with a high risk of progression to decompensated cirrhosis and hepatocellular carcinoma. The management st...

    Authors: Dengming He, Shimin Guo, Wen Chen, Xianli Chen, Guohua Yan, Jie Wang, Maoshi Li, Peng Zhu, Hongfei Huang and Yuming Wang
    Citation: BMC Infectious Diseases 2013 13:458
  29. The number of cases of hantavirus disease caused by Puumala virus is increasing enormously in Germany within the last years. Men are overrepresented in hantavirus disease and differences in course and symptoms...

    Authors: Ellen Krautkrämer, Stephan Grouls, Eva Urban, Paul Schnitzler and Martin Zeier
    Citation: BMC Infectious Diseases 2013 13:457
  30. Despite almost 30 years of effective chemotherapy with MDT, the global new case detection rate of leprosy has remained quite constant over the past years. New tools and methodologies are necessary to interrupt...

    Authors: Renate A Richardus, Khorshed Alam, David Pahan, Sabiena G Feenstra, Annemieke Geluk and Jan H Richardus
    Citation: BMC Infectious Diseases 2013 13:456
  31. Physicians depend on reliable information on the local epidemiology of infection and antibiotic resistance rates to guide empiric treatment in critically ill patients. As these data are scarce for Central Afri...

    Authors: Abraham S Alabi, Lisa Frielinghaus, Harry Kaba, Katrin Kösters, Michaëla A M Huson, Barbara C Kahl, Georg Peters, Martin P Grobusch, Saadou Issifou, Peter G Kremsner and Frieder Schaumburg
    Citation: BMC Infectious Diseases 2013 13:455
  32. Novel influenza in 2009 caused by H1N1, as well as the seasonal influenza, still are a challenge for the public health sectors worldwide. An increasing number of publications referring to this infectious disea...

    Authors: Ralph Fricke, Stefanie Uibel, Doris Klingelhoefer and David A Groneberg
    Citation: BMC Infectious Diseases 2013 13:454
  33. Genital mycoplasmas are opportunistic bacteria that are associated with undesirable gynaecologic and reproductive events. Mycoplasmas are fastidious bacteria with increasing resistance to routine antimicrobial...

    Authors: Mathys J Redelinghuys, Marthie M Ehlers, Andries W Dreyer, Hennie A Lombaard and Marleen M Kock
    Citation: BMC Infectious Diseases 2013 13:453
  34. An association between influenza A viruses and myocarditis was noted during the 1918 influenza pandemic. Since then, the link between the influenza B virus and fulminant myocarditis or cardiogenic shock has be...

    Authors: Mahnaz Taremi, Anthony Amoroso, Heather L Nace and Bruce L Gilliam
    Citation: BMC Infectious Diseases 2013 13:452
  35. Spontaneous meningitis caused by gram-negative bacilli in adult patients is uncommon and poorly characterized. Our objective is to describe and compare the characteristics and the outcome of adult patients wit...

    Authors: Virginia Pomar, Natividad Benito, Joaquin López-Contreras, Pere Coll, Mercedes Gurguí and Pere Domingo
    Citation: BMC Infectious Diseases 2013 13:451
  36. Shiga toxin-producing Escherichia coli (STEC) O157:H7 and related non-O157 STEC strains are enteric pathogens of public health concern worldwide, causing life-threatening diseases. Cattle are considered the princ...

    Authors: Patricia Jaros, Adrian L Cookson, Donald M Campbell, Thomas E Besser, Smriti Shringi, Graham F Mackereth, Esther Lim, Liza Lopez, Muriel Dufour, Jonathan C Marshall, Michael G Baker, Steve Hathaway, Deborah J Prattley and Nigel P French
    Citation: BMC Infectious Diseases 2013 13:450
  37. Most hospitals have a hierarchical design with beds positioned within cubicles and cubicles positioned within wards. Transmission of MRSA may be facilitated by patient proximity and thus the spatial arrangemen...

    Authors: Fiona Kong, David L Paterson, Michael Whitby, Michael Coory and Archie CA Clements
    Citation: BMC Infectious Diseases 2013 13:449
  38. Population based prevalence survey is an important epidemiological index to measure the burden of tuberculosis (TB) disease and monitor progress towards TB control in high burden countries like Ethiopia. This ...

    Authors: Gebretsadik Berhe, Fikre Enqueselassie, Elena Hailu, Wondale Mekonnen, Tsigemariam Teklu, Ataklti Gebretsadik, Rezene Berhe, Tewodros Haile and Abraham Aseffa
    Citation: BMC Infectious Diseases 2013 13:448
  39. Molecular diagnostics have emerged as an efficient and feasible alternative for broad detection of pathogens in faeces. However, collection of stool samples is often impractical in both clinical work and in ep...

    Authors: Jean-Claude Kabayiza, Maria E Andersson, Christina Welinder-Olsson, Tomas Bergström, Gregoire Muhirwa and Magnus Lindh
    Citation: BMC Infectious Diseases 2013 13:447
  40. Accurate knowledge of incubation period is important to investigate and to control infectious diseases and their transmission, however statements of incubation period in the literature are often uncited, incon...

    Authors: Rachel M Lee, Justin Lessler, Rose A Lee, Kara E Rudolph, Nicholas G Reich, Trish M Perl and Derek AT Cummings
    Citation: BMC Infectious Diseases 2013 13:446
  41. Outside ICUs, CVC-ABSIs epidemiology and the results of strategies for their prevention are not well known. The aim of this study was to investigate the epidemiology and the impact of a multifaceted “bundle” a...

    Authors: José Francisco García-Rodríguez, Hortensia Álvarez-Díaz, Laura Vilariño-Maneiro, María Virginia Lorenzo-García, Ana Cantón-Blanco, Patricia Ordoñez-Barrosa, Ana Isabel Mariño-Callejo and Pascual Sesma-Sánchez
    Citation: BMC Infectious Diseases 2013 13:445
  42. Pneumococcal meningitis (PM) is a life-threatening disease with a high case-fatality rate and elevated risk for serious neurological sequelae. In this study, we investigated the contribution of three major vir...

    Authors: Susanna Ricci, Alice Gerlini, Andrea Pammolli, Damiana Chiavolini, Velia Braione, Sergio Antonio Tripodi, Bruna Colombari, Elisabetta Blasi, Marco Rinaldo Oggioni, Samuele Peppoloni and Gianni Pozzi
    Citation: BMC Infectious Diseases 2013 13:444
  43. The screening of both healthcare workers and students attending teaching hospitals for latent tuberculosis infection (LTBI) is recommended in hospitals of many countries with a low-incidence of TB, including I...

    Authors: Paolo Durando, Giovanni Sotgiu, Fabio Spigno, Mauro Piccinini, Giovanni Mazzarello, Claudio Viscoli, Francesco Copello, Alessandro Poli, Filippo Ansaldi and Giancarlo Icardi
    Citation: BMC Infectious Diseases 2013 13:443
  44. Tuberculosis continues to be one of the leading causes of death worldwide and in the American region. Although multidrug-resistant tuberculosis (MDR-TB) remains a threat to TB control in Panama, few studies ha...

    Authors: Samantha Rosas, Jaime Bravo, Franklin Gonzalez, Nora de Moreno, Joel Sanchez, Ronnie G Gavilan and Amador Goodridge
    Citation: BMC Infectious Diseases 2013 13:442
  45. In Spain, the influenza vaccine effectiveness (VE) was estimated in the last three seasons using the observational study cycEVA conducted in the frame of the existing Spanish Influenza Sentinel Surveillance Sy...

    Authors: Silvia Jiménez-Jorge, Salvador de Mateo, Concha Delgado-Sanz, Francisco Pozo, Inmaculada Casas, Manuel Garcia-Cenoz, Jesús Castilla, Esteban Pérez, Virtudes Gallardo, Carolina Rodriguez, Tomás Vega, Carmen Quiñones, Eva Martínez, Juana María Vanrell, Jaume Giménez, Daniel Castrillejo…
    Citation: BMC Infectious Diseases 2013 13:441
  46. Aim of this study was to provide a detailed description of a Methicillin-resistant Staphylococcus aureus (MRSA) outbreak management strategy in the neonatal intensive care unit of a university hospital.

    Authors: Silvia Iacobelli, Benoit Colomb, Francesco Bonsante, Karine Astruc, Cyril Ferdynus, Marie-France Bouthet, Catherine Neuwirth, Ludwig Serge Aho Glélé, Pascal Chavanet and Jean-Bernard Gouyon
    Citation: BMC Infectious Diseases 2013 13:440
  47. HIV resistance affects virological response to therapy and efficacy of prophylaxis in mother-to-child-transmission. The study aims to assess the prevalence of HIV primary resistance in pregnant women naïve to ...

    Authors: Francesco Vairo, Emanuele Nicastri, Giuseppina Liuzzi, Zainab Chaula, Boniface Nguhuni, Nazario Bevilacqua, Federica Forbici, Alessandra Amendola, Lavinia Fabeni, Pasquale De Nardo, Carlo Federico Perno, Angela Cannas, Calistus Sakhoo, Maria Rosaria Capobianchi and Giuseppe Ippolito
    Citation: BMC Infectious Diseases 2013 13:439
  48. Leptospirosis is a potentially lethal zoonosis mainly affecting low-resource tropical countries, including Peru and its neighbouring countries. Timely diagnosis of leptospirosis is critical but may be challeng...

    Authors: Enrique Canal, Simon Pollett, Kristen Heitzinger, Michael Gregory, Matthew Kasper, Eric Halsey, Yocelinda Meza, Kalina Campos, Juan Perez, Rina Meza, Maruja Bernal, Alfredo Guillen, Tadeusz J Kochel, Benjamin Espinosa, Eric R Hall and Ryan C Maves
    Citation: BMC Infectious Diseases 2013 13:438
  49. Infectious diseases emerge frequently in China, partly because of its large and highly mobile population. Therefore, a rapid and cost-effective pathogen screening method with broad coverage is required for pre...

    Authors: Weiwei Huang, Yinhui Yang, Xinlei Zhang, Changan Zhao, Aihua Yin, Xiaozhuang Zhang, Zhengxin He, Yongqiang Jiang and Liang Zhang
    Citation: BMC Infectious Diseases 2013 13:437

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