World Health Organization: Meeting of the strategic advisory group of experts on immunization, April 2012 - conclusions and recommendations. World Health Organization. 2012, 87 (21): 201-216. http://www.who.int/wer/2012/wer8721.pdf,
Google Scholar
Osterholm MT, Kelley NS, Sommer A, Belongia EA: Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet Infect Dis. 2011, 12: 36-44.
PubMed
Google Scholar
Mereckiene J, Cotter S, D’Ancona F, Giambi C, Nicoll A, Levy-Bruhl D, Lopalco PL, Weber JT, Johansen K, Dematte L, Salmaso S, Stefanoff P, Greco D, Dorleans F, Polkowska A, O’Flanagan D: Differences in national influenza vaccination policies across the European Union, Norway and Iceland 2008–2009. Euro Surveill. 2010, 15 (44): 1-10. http://www.eurosurveillance.org/images/dynamic/EE/V15N44/art19700.pdf,
Google Scholar
Ministry of Health and Social Policy S: Prevención de la gripe. Recomendaciones de vacunación antigripal [Influenza prevention. Recommendations for influenza vaccination]. 2011, Spain: Ministry of Health and Social Policy, http://www.msps.es/ciudadanos/enfLesiones/enfTransmisibles/gripe/home.htm,
Google Scholar
Savulescu C, Valenciano M, de Mateo S, Larrauri A, the cycEVA Study Team: Estimating the influenza vaccine effectiveness in elderly on a yearly basis using the Spanish influenza surveillance network–pilot case–control studies using different control groups, 2008–2009 season, Spain. Vaccine. 2010, 28 (16): 2903-2907. 10.1016/j.vaccine.2010.01.054.
PubMed
Google Scholar
Savulescu C, Jimenez-Jorge S, De Mateo S, Pozo F, Casas I, Perez-Brena P, Galmes A, Vanrell JM, Rodriguez C, Vega T, Martinez A, Torner N, Ramos JM, Serrano MC, Castilla J, Garcia CM, Altzibar JM, Arteagoitia JM, Quiñones C, Perucha M, Larrauri A, on behalf of the Spanish Influenza Surveillance System: Using surveillance data to estimate pandemic vaccine effectiveness against laboratory confirmed influenza A(H1N1)2009 infection: two case controls studies, Spain, season 2009–2010. BMC Public Health. 2011, 11: 899-907. 10.1186/1471-2458-11-899.
PubMed
PubMed Central
Google Scholar
Jimenez-Jorge S, Savulescu C, Pozo F, de Mateo S, Casas I, Ledesma J, Larrauri A: Effectiveness of the 2010–11 seasonal trivalent influenza vaccine in Spain: cycEVA study. Vaccine. 2012, 30: 3595-3602. 10.1016/j.vaccine.2012.03.048.
CAS
PubMed
Google Scholar
Larrauri A, Savulescu C, Jimenez-Jorge S, Perez-Brena P, Pozo F, Casas I, Ledesma J, de Mateo S: Influenza pandemic (H1N1) 2009 activity during summer 2009. Effectiveness of the 2008–9 trivalent vaccine against pandemic influenza in Spain. Gac Sanit. 2011, 25 (1): 23-28. 10.1016/j.gaceta.2010.06.010.
PubMed
Google Scholar
Valenciano M, Ciancio B, Moren A: First steps in the design of a system to monitor vaccine effectiveness during seasonal and pandemic influenza in EU/EEA member states. Euro Surveill. 2008, 13 (43): 1-8. http://www.eurosurveillance.org/images/dynamic/EE/V13N43/art19015.pdf,
Google Scholar
Kissling E, Valenciano M: Early estimates of seasonal influenza vaccine effectiveness in Europe among target groups for vaccination: results from the I-MOVE multicentre case–control study, 2011/12. Euro Surveill. 2012, 17 (15): 1-7. http://www.eurosurveillance.org/images/dynamic/EE/V17N15/art20146.pdf,
Google Scholar
Jimenez-Jorge S, de Mateo S, Pozo F, Casas I, Garcia CM, Castilla J, Gallardo V, Perez E, Vega T, Rodriguez C, Quinones C, Martinez E, Gimenez J, Vanrell J, Castrillejo D, Serrano M, Ramos J, Larrauri A: Early estimates of the effectiveness of the 2011/12 influenza vaccine in the population targeted for vaccination in Spain, 25 December 2011 to 19 February 2012. Euro Surveill. 2012, 17 (12): 1-6. http://www.eurosurveillance.org/images/dynamic/EE/V17N12/art20129.pdf,
Google Scholar
Kissling E, Valenciano M, Larrauri A, Oroszi B, Cohen J, Nunes B, Pitigoi D, Rizzo C, Rebolledo J, Paradowska-Stankiewicz I, Jimenez-Jorge S, Horvath J, Daviaud I, Guiomar R, Necula G, Bella A, Donnell O, Gluchowska M, Ciancio B, Nicoll A, Moren A: Low and decreasing vaccine effectiveness against influenza A(H3) in 2011/12 among vaccination target groups in Europe: results from the I-MOVE multicentre case–control study. Euro Surveill. 2013, 18 (5): http://www.eurosurveillance.org/images/dynamic/EE/V18N05/art20390.pdf,
Google Scholar
Pebody R, Andrews N, McMenamin J, Durnall H, Ellis J, Thompson C, Robertson C, Cottrell S, Smyth B, Zambon M, Moore C, Fleming D, Watson J: Vaccine effectiveness of 2011/12 trivalent seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: evidence of waning intra-seasonal protection. Euro Surveill. 2013, 18 (5): http://www.eurosurveillance.org/images/dynamic/EE/V18N05/art20389.pdf,
Google Scholar
Castilla J, Martinez-Baz I, Martinez-Artola V, Reina G, Pozo F, Garcia CM, Guevara M, Moran J, Irisarri F, Arriazu M, Albeniz E, Ezpeleta C, Barricarte A: Decline in influenza vaccine effectiveness with time after vaccination, Navarre, Spain, season 2011/12. Euro Surveill. 2013, 18 (5): http://www.eurosurveillance.org/images/dynamic/EE/V18N05/art20388.pdf,
Google Scholar
Skowronski DM, Tweed SA, De Serres G: Rapid decline of influenza vaccine-induced antibody in the elderly: is it real, or is it relevant?. J Infect Dis. 2008, 197 (4): 490-502. 10.1086/524146.
PubMed
Google Scholar
European Centre for Disease Prevention and Control: Protocol for case–control studies to measure pandemic and seasonal influenza vaccine effectiveness in the European Union and European Economic Area Member States. Technical document. 2009, Stockholm, Sweden: European Centre for Disease Prevention and Control, 1-27.
Google Scholar
Rothman KJ, Greenland S, Lash TL, Rothman KJ, Greenland S, Lash TL: editors.Modern epidemiology. 2008, Philadelphia: Lippincott-Raven, 128-47. Volume 9. Validity in epidemiologic studies, 3
Google Scholar
Jackson ML, Nelson JC: The test-negative design for estimating influenza vaccine effectiveness. Vaccine. 2013, 31 (17): 2165-2168. 10.1016/j.vaccine.2013.02.053.
PubMed
Google Scholar
Foppa IM, Haber M, Ferdinands JM, Shay DK: The case test-negative design for studies of the effectiveness of seasonal influenza vaccine. Vaccine. 2013, 31 (30): 3104-3109. 10.1016/j.vaccine.2013.04.026.
PubMed
Google Scholar
Skowronski DM, De Serres G, Dickinson J, Petric M, Mak A, Fonseca K, Kwindt TL, Chan T, Bastien N, Charest H, Li Y: Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006–2007. J Infect Dis. 2009, 199 (2): 168-179. 10.1086/595862.
PubMed
Google Scholar
Fleming DM, Andrews NJ, Ellis JS, Bermingham A, Sebastianpillai P, Elliot AJ, Miller E, Zambon M: Estimating influenza vaccine effectiveness using routinely collected laboratory data. J Epidemiol Community Health. 2010, 64 (12): 1062-1067. 10.1136/jech.2009.093450.
CAS
PubMed
Google Scholar
Kelly H, Valenciano M: Estimating the effect of influenza vaccines. Lancet Infect Dis. 2012, 12 (1): 5-6. 10.1016/S1473-3099(11)70289-4. http://ac.els-cdn.com/S1473309911702894/1-s2.0-S1473309911702894-main.pdf?_tid=3b3875ecef41e3c86ee2403d8cfab8b2&acdnat=1343039760_9612548832981a739951cf59b3638fd9,
PubMed
Google Scholar
Valenciano M, Kissling E, Ciancio BC, Moren A: Study designs for timely estimation of influenza vaccine effectiveness using European sentinel practitioner networks. Vaccine. 2010, 28 (46): 7381-7388. 10.1016/j.vaccine.2010.09.010. http://www.sciencedirect.com/science/article/pii/S0264410X10013186,
PubMed
Google Scholar
Belongia EA, Kieke BA, Donahue JG, Greenlee RT, Balish A, Foust A, Lindstrom S, Shay DK: Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004–2005 season to the 2006–2007 season. J Infect Dis. 2009, 199 (2): 159-67. 10.1086/595861.
PubMed
Google Scholar
Skowronski DM, Masaro C, Kwindt TL, Mak A, Petric M, Li Y, Sebastian R, Chong M, Tam T, De Serres G: Estimating vaccine effectiveness against laboratory-confirmed influenza using a sentinel physician network: results from the 2005–2006 season of dual A and B vaccine mismatch in Canada. Vaccine. 2007, 25 (15): 2842-2851. 10.1016/j.vaccine.2006.10.002. http://www.sciencedirect.com/science/article/pii/S0264410X06011054,
CAS
PubMed
Google Scholar
Kelly H, Carville K, Grant K, Jacoby P, Tran T, Barr I: Estimation of influenza vaccine effectiveness from routine surveillance data. PLoS ONE. 2009, 4 (3): e5079-10.1371/journal.pone.0005079.
PubMed
PubMed Central
Google Scholar
Orenstein EW, De Serres G, Haber MJ, Shay DK, Bridges CB, Gargiullo P, Orenstein WA: Methodologic issues regarding the use of three observational study designs to assess influenza vaccine effectiveness. Int J Epidemiol. 2007, 36 (3): 623-631. 10.1093/ije/dym021. http://ije.oxfordjournals.org/content/36/3/623.full.pdf+html
PubMed
Google Scholar
Puig-Barbera J: 2010–2011 influenza seasonal vaccine, preliminary mid-season effectiveness estimates: reason for concern, confounding or are we following the right track?. Euro Surveill. 2011, 16 (11): http://www.eurosurveillance.org/images/dynamic/EE/V16N11/art19821.pdf,
Google Scholar
World Health Organization: Review of the 2011–2012 winter influenza season, northern hemisphere. Weekly epidemiological record. 2012, 24 (87): 233-240. http://www.who.int/wer/2012/wer8724.pdf,
Google Scholar
Centro Nacional de Epidemiología.Instituto de Salud Carlos II: Informes anuales de gripe. Vigilancia de la Gripe en España. Sistema centinela. 2012, Centro Nacional de Epidemiología.Instituto de Salud Carlos III, http://www.isciii.es/ISCIII/es/contenidos/fd-servicios-cientifico-tecnicos/fd-vigilancias-alertas/fd-enfermedades/gripe.shtml. Accessed: 10 May 2013
Google Scholar
European Centre for Disease Control and Prevention (ECDC): European Centre for Disease Control and Prevention (ECDC), Technical document. Influenza virus characterisation - Summary Europe. 2012, Stockholm, Sweden: European Centre for Disease Prevention and Control, 1-
Google Scholar
Fielding JE, Grant KA, Tran T, Kelly HA: Moderate influenza vaccine effectiveness in Victoria, Australia, 2011. Euro Surveill. 2012, 17 (11): 1-5. http://www.eurosurveillance.org/images/dynamic/EE/V17N11/art20115.pdf,
Google Scholar
Fielding JE, Grant KA, Papadakis G, Kelly HA: Estimation of type- and subtype-specific influenza vaccine effectiveness in Victoria, Australia using a test negative case control method, 2007–2008. BMC Infect Dis. 2011, 11: 170-178. 10.1186/1471-2334-11-170.
PubMed
PubMed Central
Google Scholar
Carrat F, Flahault A: Influenza vaccine: the challenge of antigenic drift. Vaccine. 2007, 25 (39–40): 6852-6862.
CAS
PubMed
Google Scholar
Centers for Disease Control and Prevention: Interim within-season estimate of the effectiveness of trivalent inactivated influenza vaccine--Marshfield, Wisconsin, 2007–08 influenza season. MMWR Morb Mortal Wkly Rep. 2008, 57 (15): 393-398. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5715a1.htm,
Google Scholar
World Health Organization: Recommended composition of influenza virus vaccines for use in the 2012–2013 northern hemisphere influenza season [Internet]. 2012, World Health Organization, 1-16. http://www.who.int/influenza/vaccines/virus/recommendations/201202_recommendation.pdf,
Google Scholar
Gross PA, Russo C, Teplitzky M, Dran S, Cataruozolo P, Munk G: Time to peak serum antibody response to influenza vaccine in the elderly. Clin Diagn Lab Immunol. 1996, 3 (3): 361-362.
CAS
PubMed
PubMed Central
Google Scholar
Brydak LB, Machala M, Mysliwska J, Mysliwski A, Trzonkowski P: Immune response to influenza vaccination in an elderly population. J Clin Immunol. 2003, 23 (3): 214-222. 10.1023/A:1023314029788.
CAS
PubMed
Google Scholar
Reber AJ, Chirkova T, Kim JH, Cao W, Biber R, Shay DK, Sambhara S: Immunosenescence and challenges of vaccination against influenza in the aging population. Aging Dis. 2012, 3 (1): 68-90. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320806/pdf/ad-3-1-68.pdf,
PubMed
Google Scholar
Kissling E, Valenciano M, Cohen JM, Oroszi B, Barret AS, Rizzo C, Stefanoff P, Nunes B, Pitigoi D, Larrauri A, Daviaud I, Horvath JK, O’Donnell J, Seyler T, Paradowska-Stankiewicz IA, Pechirra P, Ivanciuc AE, Jimenez-Jorge S, Savulescu C, Ciancio B, Moren A: I-MOVE multi-centre case control study 2010–11: overall and stratified estimates of influenza vaccine effectiveness in Europe. PLoS ONE. 2011, 6 (11): e27622-10.1371/journal.pone.0027622.
CAS
PubMed
PubMed Central
Google Scholar
Beyer WE, Palache AM, Baljet M, Masurel N: Antibody induction by influenza vaccines in the elderly: a review of the literature. Vaccine. 1989, 7 (5): 385-394. 10.1016/0264-410X(89)90150-3.
CAS
PubMed
Google Scholar
Govaert TM, Sprenger MJ, Dinant GJ, Aretz K, Masurel N, Knottnerus JA: Immune response to influenza vaccination of elderly people. A randomized double-blind placebo-controlled trial. Vaccine. 1994, 12 (13): 1185-1189. 10.1016/0264-410X(94)90241-0.
CAS
PubMed
Google Scholar
Pebody R, Hardelid P, Fleming D, McMenamin J, Andrews N, Robertson C, Thomas D, Sebastianpillai P, Ellis J, Carman W, Wreghitt T, Zambon M, Watson J: Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11. Euro Surveill. 2011, 16 (6): 1-6. http://www.eurosurveillance.org/images/dynamic/EE/V16N06/art19791.pdf,
Google Scholar
Castilla J, Moran J, Martinez-Artola V, Reina G, Martinez-Baz I, Garcia CM, Alvarez N, Irisarri F, Arriazu M, Elia F, Salcedo E: Effectiveness of trivalent seasonal and monovalent influenza A(H1N1)2009 vaccines in population with major chronic conditions of Navarre, Spain: 2010/11 mid-season analysis. Euro Surveill. 2011, 16 (7): 1-6. http://www.eurosurveillance.org/images/dynamic/EE/V16N07/art19799.pdf,
Google Scholar
Savulescu C, Jimenez-Jorge S, de Mateo S, Ledesma J, Pozo F, Casas I, Larrauri A: Effectiveness of the 2010/11 seasonal trivalent influenza vaccine in Spain: preliminary results of a case–control study. Euro Surveill. 2011, 16 (11): 1-6. http://www.eurosurveillance.org/images/dynamic/EE/V16N11/art19820.pdf,
Google Scholar
Nicoll A, Sprenger M: Low effectiveness undermines promotion of seasonal influenza vaccine. Lancet Infect Dis. 2013, 13 (1): 7-9. 10.1016/S1473-3099(12)70313-4.
PubMed
Google Scholar