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  1. Antiretroviral therapy dramatically reduced HIV-related morbidity and mortality, prolonging the lifespan of HIV-infected patients. Greater duration of infection and exposure to antiretroviral therapy makes the...

    Authors: Ana Rita Coelho, Flávia Andreia Moreira, Ana Cristina Santos, André Silva-Pinto, António Sarmento, Davide Carvalho and Paula Freitas
    Citation: BMC Infectious Diseases 2018 18:309
    Content type: Research article Published on:

  2. Toxoplasma gondii is a protozoan parasite with worldwide distribution, infecting a broad-range of humans and warm-blooded animals. In the current study, role of this parasite on secondary sex ratio and risk of mi...

    Authors: Saeedeh Shojaee, Aref Teimouri, Hossein Keshavarz, Sanaz Jafarpour Azami and Sahar Nouri
    Citation: BMC Infectious Diseases 2018 18:307
    Content type: Research article Published on:

  3. Cystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial. The aim of ...

    Authors: Virginia Velasco-Tirado, Montserrat Alonso-Sardón, Amparo Lopez-Bernus, Ángela Romero-Alegría, Francisco Javier Burguillo, Antonio Muro, Adela Carpio-Pérez, Juan Luis Muñoz Bellido, Javier Pardo-Lledias, Miguel Cordero and Moncef Belhassen-García
    Citation: BMC Infectious Diseases 2018 18:306
    Content type: Research article Published on:

  4. Streptococcus Group B (GBS) colonization in pregnant women is the most important risk factor for newborn disease due to vertical transmission during delivery. GBS colonization during pregnancy has been implicated...

    Authors: J. A. Carrillo-Ávila, J. Gutiérrez-Fernández, A. I. González-Espín, E. García-Triviño and L. G. Giménez-Lirola
    Citation: BMC Infectious Diseases 2018 18:305
    Content type: Research article Published on:

  5. Female genital tuberculosis (FGTB) is known to cause severe tubal disease leading to infertility and its incidence closely parallels with the overall prevalence of tuberculosis (TB) in a community. Its magnitu...

    Authors: Sileshi Abdissa, Tamrat Abebe, Gobena Ameni, Sisay Teklu, Yonas Bekuretsion, Markos Abebe and Adane Mihret
    Citation: BMC Infectious Diseases 2018 18:304
    Content type: Research article Published on:

  6. We have previously shown that 8 weeks’ treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D3 (vitD3) (5000 IU/day) as host-directed therapy (HDT) accelerated clinical recovery, sputum cultu...

    Authors: Rokeya Sultana Rekha, Akhirunnesa Mily, Tajnin Sultana, Ahsanul Haq, Sultan Ahmed, S. M. Mostafa Kamal, Annemarie van Schadewijk, Pieter S. Hiemstra, Gudmundur H. Gudmundsson, Birgitta Agerberth and Rubhana Raqib
    Citation: BMC Infectious Diseases 2018 18:303
    Content type: Research article Published on:

  7. To describe extra-haematological manifestations associated with human parvovirus B19 (HPV-B19) infection.

    Authors: Marion Dollat, Benjamin Chaigne, Grégoire Cormier, Nathalie Costedoat-Chalumeau, François Lifermann, Alban Deroux, Emilie Berthoux, Emmanuelle Dernis, Thomas Sené, Gilles Blaison, Olivier Lambotte, Benjamin Terrier, Jérémie Sellam, Luc De Saint-Martin, Laurent Chiche, Nicolas Dupin…
    Citation: BMC Infectious Diseases 2018 18:302
    Content type: Research article Published on:

  8. The first autochthonous Zika virus (ZIKV) outbreak in Singapore was detected in August 2016. We report an analysis of the correlation of clinical illness with viremia and laboratory parameters in this Asian co...

    Authors: Deborah H. L. Ng, Hanley J. Ho, Angela Chow, Joshua Wong, Win Mar Kyaw, Adriana Tan, Po Ying Chia, Chiaw Yee Choy, Glorijoy Tan, Tsin Wen Yeo and Yee Sin Leo
    Citation: BMC Infectious Diseases 2018 18:301
    Content type: Research article Published on:

  9. Most infections are spread through social networks (detrimental effect). However, social networks may also lower infection acquisition (beneficial effect). This study aimed to examine associations between soci...

    Authors: Stephanie Brinkhues, Miranda T. Schram, Christian J. P. A. Hoebe, Mirjam E. E. Kretzschmar, Annemarie Koster, Pieter C. Dagnelie, Simone J. S. Sep, Sander M. J. van Kuijk, Paul H. M. Savelkoul and Nicole H. T. M. Dukers-Muijrers
    Citation: BMC Infectious Diseases 2018 18:300
    Content type: Research article Published on:

  10. Efficient and effective strategies for identifying cases of active tuberculosis (TB) in rural sub-Saharan Africa are lacking. Household contact tracing offers a potential approach to diagnose more TB cases, an...

    Authors: Kristen M. Little, Reginah Msandiwa, Neil Martinson, Jonathan Golub, Richard Chaisson and David Dowdy
    Citation: BMC Infectious Diseases 2018 18:299
    Content type: Research article Published on:

  11. The introduction of anti-retroviral treatment (ART) has significantly reduced mortality and morbidity associated with HIV/AIDS. While treatment at early stages of the disease is related to a better prognosis, ...

    Authors: Henry Namme Luma, Paulia Jua, Olivier-Tresor Donfack, Felicite Kamdem, Eveline Ngouadjeu, Hugo Bertrand Mbatchou, Marie-Solange Doualla and Yakouba Njankou Mapoure
    Citation: BMC Infectious Diseases 2018 18:298
    Content type: Research article Published on:

  12. Many of the currently used models of bacterial meningitis have limitations due to direct inoculation of pathogens into the cerebrospinal fluid or brain and a relatively insensitive assessment of long-term sequ...

    Authors: Jana Seele, Simone C. Tauber, Stephanie Bunkowski, Christoph G. Baums, Peter Valentin-Weigand, Nicole de Buhr, Andreas Beineke, Asparouh I. Iliev, Wolfgang Brück and Roland Nau
    Citation: BMC Infectious Diseases 2018 18:297
    Content type: Research article Published on:

  13. Acute respiratory infections (ARIs) remains a disease of public health importance in Nigeria. Though, previous studies have identified factors associated with childhood ARI symptoms, the progress made in reduc...

    Authors: Joshua Odunayo Akinyemi and Oyewale Mayowa Morakinyo
    Citation: BMC Infectious Diseases 2018 18:296
    Content type: Research article Published on:

  14. Tuberculosis (TB) and chronic Hepatitis B virus (HBV) infection are common in China. Fist-line anti-TB medications often produce drug-induced liver injury (DILI). This study sought to investigate whether TB pa...

    Authors: Lubiao Chen, Dujing Bao, Lin Gu, Yurong Gu, Liang Zhou, Zhiliang Gao and Yuehua Huang
    Citation: BMC Infectious Diseases 2018 18:295
    Content type: Research article Published on:

  15. Tuberculous (TB) pneumonia can induce acute respiratory distress syndrome (ARDS). Although TB pneumonia is one of the causes of disease and death among children worldwide, the literature on TB pneumonia-induce...

    Authors: Dong Tien Ngo, Phuc Huu Phan, Shoji Kawachi, Noriko Nakajima, Naoyuki Hirata, Akira Ainai, Thuy Thi Bich Phung, Dien Minh Tran and Hai Thanh Le
    Citation: BMC Infectious Diseases 2018 18:294
    Content type: Case report Published on:

  16. According to the traditional tuberculosis (TB) treatment paradigm, the initial doses of treatment rapidly kill most Mycobacterium tuberculosis (Mtb) bacilli in sputum, yet many more months of daily treatment are ...

    Authors: Nicholas D. Walter, Camille M. Moore, Xavier A. Kayigire, Christian Dide-Agossou, William Worodria, Laurence Huang, Charles K. Everett, Gary S. Schoolnik, Payam Nahid and J. Lucian Davis
    Citation: BMC Infectious Diseases 2018 18:293
    Content type: Research article Published on:

  17. Among 2179 Salmonella isolates obtained during national surveillance for salmonellosis in China from 2005 to 2013, we identified 46 non-H2S-producing strains originating from different sources.

    Authors: Jing Xie, Fuli Wu, Xuebin Xu, Xiaoxia Yang, Rongtao Zhao, Qiuxia Ma, Peng Li, Ligui Wang, Rongzhang Hao, Leiji Jia, Xinying Du, Shaofu Qiu and Hongbin Song
    Citation: BMC Infectious Diseases 2018 18:292
    Content type: Research article Published on:

  18. The epidemiology of maternal and infant Group B streptococcus (GBS) colonization is poorly understood in China. The aim of this study is to explore the prevalence and risk factors associated with maternal and ...

    Authors: Jichang Chen, Jinjian Fu, Wei Du, Xin Liu, Chokechai Rongkavilit, Xuemei Huang, Yubi Wu, Yuanliu Wang and Eric McGrath
    Citation: BMC Infectious Diseases 2018 18:291
    Content type: Research article Published on:

  19. Although intravesical bacille Calmette-Guérin (BCG) therapy is accepted as an effective treatment for bladder cancer, serious complications may occur in rare cases. To date, only 4 cases have been reported in ...

    Authors: Takuya Kusakabe, Kenji Endo, Itaru Nakamura, Hidekazu Suzuki, Hirosuke Nishimura, Shinji Fukushima and Kengo Yamamoto
    Citation: BMC Infectious Diseases 2018 18:290
    Content type: Case report Published on:

  20. Cytomegalovirus (CMV) infection is common in immunocompetent patients in intensive care units (ICUs). However, whether CMV infection or CMV reactivation contributes to mortality of immunocompetent patients rem...

    Authors: Xi Li, Yongbo Huang, Zhiheng Xu, Rong Zhang, Xiaoqing Liu, Yimin Li and Pu Mao
    Citation: BMC Infectious Diseases 2018 18:289
    Content type: Research article Published on:

  21. Hepatitis B vaccination is the most effective method of prevention for hepatitis B virus infection. It is a major public health problem in Nigeria, and health workers are at increased risk. This study determin...

    Authors: I. B. Omotowo, I. A. Meka, U. N. Ijoma, V. E. Okoli, O. Obienu, T. Nwagha, A. C. Ndu, D. O. Onodugo, L. C. Onyekonwu and E. O. Ugwu
    Citation: BMC Infectious Diseases 2018 18:288
    Content type: Research article Published on:

  22. From September 2016–April 2017, Am Timan, Chad, experienced a large HEV outbreak in an urban setting with a limited impact in terms of morbidity and mortality. To better understand HEV epidemiology in this con...

    Authors: Larissa Vernier, Annick Lenglet, Boris M. Hogema, Ali M. Moussa, Cono Ariti, Simone Vollmer, Andrea Irwin, Prince Alfani, Sibylle Sang and Charity Kamau
    Citation: BMC Infectious Diseases 2018 18:287
    Content type: Research article Published on:

  23. Schizophyllum commune, a basidiomycetous fungus, is a common invader of rotten wood. This fungus rarely causes mycotic disease in humans, especially cutaneous infection. In this paper, we describe the first case ...

    Authors: Lidi Tian, Yunzhu Mu, Hao Zhang, Xiaocui Su, Chuan Yang, Xianzhu Shu and Defu Qing
    Citation: BMC Infectious Diseases 2018 18:286
    Content type: Case report Published on:

  24. Triple-drug regimens are the gold standard for HIV therapy. Nucleos(t)ide reverse transcriptase inhibitors (NRTIs) reducing regimens are used to decrease drugs toxicity, exposure and costs. Aim of our study wa...

    Authors: Eugenia Quiros-Roldan, Paola Magro, Elena Raffetti, Ilaria Izzo, Alessandro Borghetti, Francesca Lombardi, Annalisa Saracino, Franco Maggiolo and Francesco Castelli
    Citation: BMC Infectious Diseases 2018 18:285
    Content type: Research article Published on:

  26. The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of mother-to-child tra...

    Authors: Aklilu Endalamaw, Amare Demsie, Setegn Eshetie and Tesfa Dejenie Habtewold
    Citation: BMC Infectious Diseases 2018 18:283
    Content type: Research article Published on:

  27. Dengue and West Nile viruses are highly cross-reactive and have numerous parallels in geography, potential vector host (Aedes family of mosquitoes), and initial symptoms of infection. While the vast majority (> 8...

    Authors: Megan E. Cahill, Samantha Conley, Andrew T. DeWan and Ruth R. Montgomery
    Citation: BMC Infectious Diseases 2018 18:282
    Content type: Research article Published on:

  28. Hepatitis C (HCV) diagnosis and care is a major challenge for people who use illicit drugs, and is characterised by low rates of testing and treatment engagement globally. New approaches to fostering engagemen...

    Authors: Andy Guise, T. Charles Witzel, Sema Mandal, Caroline Sabin, Tim Rhodes, Anthony Nardone and Magdalena Harris
    Citation: BMC Infectious Diseases 2018 18:281
    Content type: Research article Published on:

  29. Retention in care and adherence to the treatment is very important for the success of the program while access for treatment is being scaled up. Without more precise data about the rate of loss to follow up as...

    Authors: Wubareg Seifu, Walid Ali and Beyene Meresa
    Citation: BMC Infectious Diseases 2018 18:280
    Content type: Research article Published on:

  30. Hepatitis B virus (HBV) infection is a world health problem with an estimated 257 million chronically infected people. Indonesia, with 7.1% prevalence of hepatitis B surface antigen (HBsAg), is classified as a...

    Authors: Teguh Wijayadi, Rizalinda Sjahril, Turyadi, Susan I. Ie, Ridha Wahyuni, Ilhamjaya Pattelongi, M. Nasrum Massi, Irawan Yusuf and David H Muljono
    Citation: BMC Infectious Diseases 2018 18:279
    Content type: Research article Published on:

  31. Helicobacter pylori is a Gram negative bacterium that colonizes the stomach of approximately two-thirds of the human population and it is involved in the pathogenesis of gastroduodenal diseases. This study sought...

    Authors: Laure Brigitte Kouitcheu Mabeku, Michelle Larissa Noundjeu Ngamga and Hubert Leundji
    Citation: BMC Infectious Diseases 2018 18:278
    Content type: Research article Published on:

  32. Antibiotics with anaerobic coverage are widely used for the treatment of biliary tract infection (BTI), even in the absence of isolated anaerobes. The current study aimed to investigate the differences in clin...

    Authors: Pei-Shan Wu, Chien Chuang, Ping-Feng Wu, Yi-Tsung Lin and Fu-Der Wang
    Citation: BMC Infectious Diseases 2018 18:277
    Content type: Research article Published on:

  33. In the past two decades, Rift Valley Fever (RVF) outbreaks have been reported twice in Tanzania, with the most recent outbreak occurring in 2006/07. Given the ecology and climatic factors that support mosquito...

    Authors: Abade Ahmed, Jabir Makame, Fyumagwa Robert, Keyyu Julius and Matee Mecky
    Citation: BMC Infectious Diseases 2018 18:276
    Content type: Research article Published on:

  34. Zika virus (ZIKV) had spread rapidly in the past few years in southern hemisphere where dengue virus (DENV) had caused epidemic problems for over half a century. The high degree of cross-reactivity of Envelope...

    Authors: Xiujie Gao, Yingfen Wen, Jian Wang, Wenxin Hong, Chunlin Li, Lingzhai Zhao, Chibiao Yin, Xia Jin, Fuchun Zhang and Lei Yu
    Citation: BMC Infectious Diseases 2018 18:275
    Content type: Research article Published on:

  35. Infants born to hepatitis B surface antigen (HBsAg) positive mothers are at a higher risk for Hepatitis B virus (HBV) infection. Host genetic background plays an important role in determining the strength of i...

    Authors: Meng Zhuo Cao, Yan Hua Wu, Si Min Wen, Yu Chen Pan, Chong Wang, Fei Kong, Chuan Wang, Jun Qi Niu, Jie Li and Jing Jiang
    Citation: BMC Infectious Diseases 2018 18:274
    Content type: Research article Published on:

  36. Due to the increasing number of DCD transplantations since 2015, the transmission of rabies through solid organ transplantation has become a notable problem in China and has attracted the attention of the public.

    Authors: Jian Zhang, Jun Lin, Ye Tian, Linlin Ma, Wen Sun, Lei Zhang, Yichen Zhu, Wei Qiu and Lujia Zhang
    Citation: BMC Infectious Diseases 2018 18:273
    Content type: Case report Published on:

  37. Timely HIV testing and initiation of antiretroviral therapy are two major determinants of survival for HIV-infected individuals. Our study aimed to explore the trend of late HIV/AIDS diagnoses and to assess th...

    Authors: Houlin Tang, Yurong Mao, Weiming Tang, Jing Han, Juan Xu and Jian Li
    Citation: BMC Infectious Diseases 2018 18:272
    Content type: Research article Published on:

  38. Invasive pulmonary aspergillosis (IPA) has been increasingly reported in patients with underlying respiratory diseases (URD). Early diagnosis of IPA is crucial for mortality reduction and improved prognosis, y...

    Authors: Wei Xiao, De-ying Gong, Bing Mao, Xin-miao Du, Lin-Li Cai, Min-yu Wang and Juan-juan Fu
    Citation: BMC Infectious Diseases 2018 18:271
    Content type: Study protocol Published on:

  39. Consideration to add empiric MRSA therapy with vancomycin is a common clinical dilemma. However, vancomycin overuse has important adverse events. MRSA colonization screening is commonly performed for infection...

    Authors: Guillaume Butler-Laporte, Matthew P. Cheng, Emily G. McDonald and Todd C. Lee
    Citation: BMC Infectious Diseases 2018 18:270
    Content type: Research article Published on:

  40. Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within age strata using surveillance data ...

    Authors: Saverio Caini, Peter Spreeuwenberg, Gabriela F. Kusznierz, Juan Manuel Rudi, Rhonda Owen, Kate Pennington, Sonam Wangchuk, Sonam Gyeltshen, Walquiria Aparecida Ferreira de Almeida, Cláudio Maierovitch Pessanha Henriques, Richard Njouom, Marie-Astrid Vernet, Rodrigo A. Fasce, Winston Andrade, Hongjie Yu, Luzhao Feng…
    Citation: BMC Infectious Diseases 2018 18:269
    Content type: Research article Published on:

  41. Understanding the population genetics of pneumococci will allow detection of changes in the prevalence of circulating genotypes and evidence for capsular switching. We aimed to analyze the genetic structure of...

    Authors: Ki Wook Yun, Eun Hwa Choi, Hoan Jong Lee, Jin Han Kang, Kyung-Hyo Kim, Dong Soo Kim, Yae-Jean Kim, Byung Wook Eun, Sung Hee Oh, Hye-Kyung Cho, Young Jin Hong, Kwang Nam Kim, Nam Hee Kim, Yun-Kyung Kim, Hyunju Lee, Taekjin Lee…
    Citation: BMC Infectious Diseases 2018 18:268
    Content type: Research article Published on:

  42. Central line-associated bloodstream infections (CLABSI) are a major source of sepsis in modern intensive care medicine. Some years ago bundle interventions have been introduced to reduce CLABSI. The use of che...

    Authors: Dominic Wichmann, Cristina E. Belmar Campos, Stephan Ehrhardt, Timo Kock, Claudia Weber, Holger Rohde and Stefan Kluge
    Citation: BMC Infectious Diseases 2018 18:267
    Content type: Research article Published on:

  43. Antiretroviral therapy has an impressive clinical effect on the human immunodeficiency virus although its effectiveness depends mainly on the adherence of patients to the therapy. Therefore, this study aimed t...

    Authors: Abiyot Abeje Molla, Abebaw Addis Gelagay, Habtamu Sewunet Mekonnen and Destaw Fetene Teshome
    Citation: BMC Infectious Diseases 2018 18:266
    Content type: Research article Published on:

  44. The recurrence of tuberculosis (TB) disease in treated patients can serve as a marker of the efficacy of TB control programs. Recurrent disease represents either endogenous reactivation with the same strain of My...

    Authors: Laila Parvaresh, Taryn Crighton, Elena Martinez, Andrea Bustamante, Sharon Chen and Vitali Sintchenko
    Citation: BMC Infectious Diseases 2018 18:265
    Content type: Research article Published on:

  45. Blood transfusion is associated with several risks particularly exposure to blood transfusion-transmissible infections (TTI), including: Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human immunodeficiency...

    Authors: Nejat Siraj, Oliver Okoth Achila, John Issac, Efrem Menghisteab, Maedn Hailemariam, Semere Hagos, Yosan Gebremeskel and Daniel Tesfamichael
    Citation: BMC Infectious Diseases 2018 18:264
    Content type: Research article Published on:

  46. HIV-positive people often experience mental health disorders and engage in substance use when the disease progresses. In resource limited settings, mental health services are not integrated into HIV services. ...

    Authors: Khem N. Pokhrel, Vidya D. Sharma, Kalpana G. Pokhrel, Sanjeev R. Neupane, Linda B. Mlunde, Krishna C. Poudel and Masamine Jimba
    Citation: BMC Infectious Diseases 2018 18:263
    Content type: Research article Published on:

  47. Tuberculosis (TB) case finding is an important component of TB control because it can reduce transmission of Mycobacterium tuberculosis (MTB) through prompt detection and treatment of infectious patients.

    Authors: Godfrey Bigogo, Kevin Cain, Diana Nyole, Geoffrey Masyongo, Joshua Auko Auko, Newton Wamola, Albert Okumu, Janet Agaya, Joel Montgomery, Martien Borgdorff and Deron Burton
    Citation: BMC Infectious Diseases 2018 18:262
    Content type: Research article Published on:

  48. Limited treatment options of extensive drug-resistant tuberculosis (XDR-TB) have led to its high mortality worldwide. Relevant data about mortality of XDR-TB patients in literature are limited and likely under...

    Authors: Chengli Bei, Manjiao Fu, Yao Zhang, Hebin Xie, Ke Yin, Yanke Liu, Li Zhang, Bangruan Xie, Fang Li, Hua Huang, Yuhong Liu, Li Yang and Jing Zhou
    Citation: BMC Infectious Diseases 2018 18:261
    Content type: Research article Published on:

  49. Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection in the world. It can result in various upper gastroduodenal diseases. The prevalence varies among countries, population gro...

    Authors: Abdurahaman Seid and Wondmagegn Demsiss
    Citation: BMC Infectious Diseases 2018 18:260
    Content type: Research article Published on:

  50. Brucella abortus is a highly pathogenic zoonotic agent, tempting for the development of a rapid diagnostic method to enable adequate treatment and prevent further spread. Enrichment of the bacteria is often used ...

    Authors: Rene Kaden, Sevinc Ferrari, Tomas Jinnerot, Martina Lindberg, Tara Wahab and Moa Lavander
    Citation: BMC Infectious Diseases 2018 18:259
    Content type: Research article Published on:

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