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  1. France is the European country with the lowest level of confidence in vaccines. Measurement of patients’ acceptability towards a future therapeutic HIV vaccine is critically important. Thus, the aim of this st...

    Authors: Svetlane Dimi, David Zucman, Olivier Chassany, Christophe Lalanne, Thierry Prazuck, Emmanuel Mortier, Catherine Majerholc, Isabelle Aubin-Auger, Pierre Verger and Martin Duracinsky
    Citation: BMC Infectious Diseases 2019 19:401
    Content type: Research article Published on:

  2. Older adults are vulnerable to hospitalization or death from norovirus infection, but the actual disease burden remains unknown. Therefore, we conducted a nationwide survey to estimate the number of inpatients...

    Authors: Satoko Ohfuji, Kyoko Kondo, Kazuya Ito, Tetsuo Kase, Akiko Maeda, Wakaba Fukushima, Taisei Masuda and Munehide Kano
    Citation: BMC Infectious Diseases 2019 19:400
    Content type: Research article Published on:

  3. Uptake of Human Immunodeficiency Virus (HIV) re-testing among postnatal mothers who had previously tested HIV-negative is crucial for the detection of recent seroconverters who are likely to have high plasma v...

    Authors: Saumu Iddy Nungu, Janneth Maridadi Mghamba, Susan Fred Rumisha and Innocent Antony Semali
    Citation: BMC Infectious Diseases 2019 19:398
    Content type: Research article Published on:

  4. Leptospirosis or Weil’s disease is caused by pathogenic spirochete bacteria called Leptospira. It is considered the most common zoonosis in the world and is usually transmitted by urine of rodents and dogs with a...

    Authors: Alexander Maier, Rafael Kaeser, Robert Thimme and Tobias Boettler
    Citation: BMC Infectious Diseases 2019 19:395
    Content type: Case report Published on:

  5. Thrombotic thrombocytopenic purpura (TTP) is a rare, potentially fatal disease with multisystem involvement. Cytomegalovirus (CMV) infection as a cause of refractory TTP, has been reported only in immunocompro...

    Authors: Medhini Boteju, Praveen Weeratunga, Ahalyaa Sivashangar and Thashi Chang
    Citation: BMC Infectious Diseases 2019 19:394
    Content type: Case report Published on:

  6. Human immunodeficiency virus, hepatitis B virus and hepatitis C virus are among the greatest threats to blood safety for the recipient. They are also the leading cause of death, chronic and life-threatening ab...

    Authors: Abiye Tigabu, Tigist Engda and Feleke Mekonnen
    Citation: BMC Infectious Diseases 2019 19:393
    Content type: Research article Published on:

  7. In Lao PDR, the epidemiology of varicella infection is uncertain, since it is not a notifiable disease and VZV outbreaks are rarely reported as fever/rash (F/R) diseases.

    Authors: Phonethipsavanh Nouanthong, Judith M. Hübschen, Somxay Billamay, Sodaly Mongkhoune, Keooudomphone Vilivong, Vilaysone Khounvisith, Regina Sinner, Marc Grandadam, Darouny Phonekeo, Antony P. Black and Claude P. Muller
    Citation: BMC Infectious Diseases 2019 19:392
    Content type: Research article Published on:

  8. Most studies assessing drug resistant tuberculosis (DRTB) in human immunodeficiency virus (HIV) co-infected patients in India have used conventional culture- based systems to diagnose DRTB that have a longer t...

    Authors: Neil Saldanha, Kiran Runwal, Charulata Ghanekar, Sunil Gaikwad, Shrivallabh Sane and Sanjay Pujari
    Citation: BMC Infectious Diseases 2019 19:391
    Content type: Research article Published on:

  11. The compound letermovir (LMV) has recently been approved for the prophylaxis of cytomegalovirus (CMV) infection and disease in adult CMV seropositive recipients of an allogeneic hematopoietic stem cell transpl...

    Authors: Susanne Jung, Manuela Michel, Thomas Stamminger and Detlef Michel
    Citation: BMC Infectious Diseases 2019 19:388
    Content type: Case report Published on:

  12. In August 2017, the Uganda Ministry of Health was notified of increased cases of multidrug-resistant tuberculosis (MDR-TB) in Arua District, Uganda during 2017. We investigated to identify the scope of the inc...

    Authors: Denis Okethwangu, Doreen Birungi, Claire Biribawa, Benon Kwesiga, Stavia Turyahabwe, Alex R. Ario and Bao-Ping Zhu
    Citation: BMC Infectious Diseases 2019 19:387
    Content type: Research article Published on:

  13. Ewingella americana (Ea) is a Gram-negative, lactose-fermenting, oxidase-negative and catalase-positive bacterium that was first described in 1983 as a new genus and species in the family Enterobacteriaceae. It i...

    Authors: Susanna Esposito, Francesco Miconi, Daniela Molinari, Emanuela Savarese, Federica Celi, Livio Marchese, Sara Valloscuro, Giovanni Miconi and Nicola Principi
    Citation: BMC Infectious Diseases 2019 19:386
    Content type: Case report Published on:

  15. An outbreak of Candida auris began globally in 2014 including Pakistan and since then it has emerged as a nosocomial multi-drug resistant pathogen. The aim of this study was to assess the clinical spectrum and ou...

    Authors: Muneeba Ahsan Sayeed, Joveria Farooqi, Kausar Jabeen, Safia Awan and Syed Faisal Mahmood
    Citation: BMC Infectious Diseases 2019 19:384
    Content type: Research article Published on:

  16. Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections. The human immunodeficienc...

    Authors: Henok Mulugeta, Getenet Dessie, Fasil Wagnew, Dube Jara, Cheru Tesema Leshargie and Ayenew Negesse
    Citation: BMC Infectious Diseases 2019 19:383
    Content type: Research article Published on:

  17. Herpes simplex virus type-2 (HSV-2) infection is the main cause of genital ulcer disease and increases the risk of HIV acquisition. Little information is available regards the epidemiological characteristics o...

    Authors: Pengcheng Huai, Furong Li, Zhen Li, Lele Sun, Xi’an Fu, Qing Pan, Gongqi Yu, Zemin Chai, Tongsheng Chu, Zihao Mi, Fangfang Bao, Honglei Wang, Bingni Zhou, Chuan Wang, Yonghu Sun, Guiye Niu…
    Citation: BMC Infectious Diseases 2019 19:382
    Content type: Research article Published on:

  18. The epidemiology of hepatitis B virus (HBV) infection in the general population in Rwanda is not well known. This study examined the prevalence of HBV surface antigen (HBsAg) positivity and associated risk fac...

    Authors: Jean Damascene Makuza, Jean Olivier Twahirwa Rwema, Corneille Killy Ntihabose, Donatha Dushimiyimana, Justine Umutesi, Marie Paul Nisingizwe, Janvier Serumondo, Muhamed Semakula, David J. Riedel and Sabin Nsanzimana
    Citation: BMC Infectious Diseases 2019 19:381
    Content type: Research article Published on:

  19. Antiretroviral therapy (ART) has significantly decreased HIV/AIDS-related morbidity and mortality. However, globally, many people living with HIV die from non-AIDS related illnesses including liver diseases wh...

    Authors: Faustina Pappoe, Charles Kofi Oheneba Hagan, Dorcas Obiri-Yeboah and Paul Nsiah
    Citation: BMC Infectious Diseases 2019 19:380
    Content type: Research article Published on:

  20. The incidence of tuberculosis (TB) remains high worldwide. Current strategies will not eradicate TB by 2035; instead, by 2182 is more likely. Therefore, it is urgent that new risk factors be identified.

    Authors: Yingjie Zhang, Mengyang Liu, Samuel S. Wu, Hui Jiang, Junjie Zhang, Songwang Wang, Wei Ma, Qihuan Li, Yuan Ma, Yue Liu, Wei Feng, Endawoke Amsalu, Xia Li, Wei Wang, Weimin Li and Xiuhua Guo
    Citation: BMC Infectious Diseases 2019 19:379
    Content type: Research article Published on:

  21. Treatments for Hepatitis C virus (HCV) infection have vastly improved over the past few decades with current regimens now offering pangenotypic activity with excellent cure rates reported in clinical trials, i...

    Authors: A. Maughan, K. Sadigh, V. Angulo-Diaz, C. Mandimika, M. Villanueva, J. K. Lim and O. Ogbuagu
    Citation: BMC Infectious Diseases 2019 19:378
    Content type: Research article Published on:

  22. Climate change is expected to increase the chance of extreme rainfall events in the Northern Hemisphere and herewith, there is an increased chance of urban pluvial flooding. Urban pluvial flooding often consis...

    Authors: Annemieke Christine Mulder, Roan Pijnacker, Heleen de Man, Jan van de Kassteele, Wilfrid van Pelt, Lapo Mughini-Gras and Eelco Franz
    Citation: BMC Infectious Diseases 2019 19:377
    Content type: Research article Published on:

  23. Management of Ebola virus disease (EVD) has historically focused on infection prevention, case detection and supportive care. Several specific anti-Ebola therapies have been investigated, including during the ...

    Authors: James S. Lee, Neill K. J. Adhikari, Henry Y. Kwon, Koren Teo, Reed Siemieniuk, François Lamontagne, Adrienne Chan, Sharmistha Mishra, Srinivas Murthy, Peter Kiiza, Jan Hajek, Elhadj I. Bah, Marie-Claire Lamah, Raymond Kao and Robert A. Fowler
    Citation: BMC Infectious Diseases 2019 19:376
    Content type: Research article Published on:

  24. This study was undertaken to determine the distribution of type-specific human papillomavirus (HPV) in external anogenital warts, and the correlation with clinical presentation of warts and demographic data of...

    Authors: Rana Al-Awadhi, Nawaf Al-Mutairi, Ahmed N. Albatineh and Wassim Chehadeh
    Citation: BMC Infectious Diseases 2019 19:375
    Content type: Research article Published on:

  25. Dosages of anti-tuberculosis (TB) drugs are recommended to be adjusted according to renal function for patients complicated with chronic kidney disease (CKD). However, the efficacy and safety outcomes of such ...

    Authors: Nayuta Saito, Yutaka Yoshii, Yugo Kaneko, Akio Nakashima, Tsugumi Horikiri, Zenya Saito, Sho Watanabe, Akira Kinoshita, Keisuke Saito and Kazuyoshi Kuwano
    Citation: BMC Infectious Diseases 2019 19:374
    Content type: Research article Published on:

  26. Body mass index (BMI) may contribute somewhat to drug metabolism, and thus affecting the efficacy of highly active antiretroviral therapy (HAART). This study aimed to determine the frequencies of underweight, ...

    Authors: Xiaolin Li, Haibo Ding, Wenqing Geng, Jing Liu, Yongjun Jiang, Junjie Xu, Zining Zhang and Hong Shang
    Citation: BMC Infectious Diseases 2019 19:373
    Content type: Research article Published on:

  27. In the UK, hepatitis B virus (HBV) incidence is associated with migrants from particular high-burden countries and population groups deemed ‘hard-to-reach’ by standard healthcare services: the homeless, people...

    Authors: Josephine E. B. Taylor, Julian Surey, Jennifer MacLellan, Marie Francis, Ibrahim Abubakar and Helen R. Stagg
    Citation: BMC Infectious Diseases 2019 19:372
    Content type: Research article Published on:

  28. There is an ongoing outbreak of Mycobacterium chimaera infections among patients exposed to contaminated heater-cooler devices used during cardiac surgery. Recognition of M. chimaera infection is hampered by its ...

    Authors: Jim Nomura, Gunter Rieg, Gary Bluestone, Townson Tsai, Andrew Lai, Dawn Terashita, Sivan Bercovici, David K. Hong and Brian P. Lee
    Citation: BMC Infectious Diseases 2019 19:371
    Content type: Research article Published on:

  29. Several inactivated enterovirus-A71 (EV-A71) vaccines are currently licensed in China; however, the development of additional EV-A71 vaccines is ongoing, necessitating extensive analysis of the molecular epide...

    Authors: Lea Necitas Apostol, Hiroyuki Shimizu, Akira Suzuki, Rifqiyah Nur Umami, Maria Melissa Ann Jiao, Amado Tandoc III, Mariko Saito, Socorro Lupisan and Hitoshi Oshitani
    Citation: BMC Infectious Diseases 2019 19:370
    Content type: Research article Published on:

  30. Urinary tract infections (UTIs) are one of the most common bacterial infections. High recurrence rates and the increasing antibiotic resistance among uropathogens constitute a large social and economic problem...

    Authors: Urszula Wnorowska, Ewelina Piktel, Bonita Durnaś, Krzysztof Fiedoruk, Paul B. Savage and Robert Bucki
    Citation: BMC Infectious Diseases 2019 19:369
    Content type: Research article Published on:

  31. The Joint United Nations Programme on HIV/AIDS 90–90-90 goal envisions 90% of all people receiving antiretroviral therapy to be virally suppressed by 2020. Implied in that goal is that viral load be quantified...

    Authors: Seema T. Meloni, Oche Agbaji, Charlotte A. Chang, Patricia Agaba, Godwin Imade, Stephen Oguche, Ahmed Mukhtar, Kiren Mitruka, Mackenzie Hurlston Cox, Aaron Zee and Phyllis Kanki
    Citation: BMC Infectious Diseases 2019 19:368
    Content type: Study protocol Published on:

  33. Independent of HIV infection, extrapulmonary TB (EPTB) risk is increased in women, persons of black race or foreign birth, and by genetic variants in vitamin D receptor (VDR), interleukin-1 beta (IL-1β), and t...

    Authors: Christina T. Fiske, Amondrea Blackman, Fernanda Maruri, Peter F. Rebeiro, Moises Huaman, Jamie Kator, Holly M. Scott Algood and Timothy R. Sterling
    Citation: BMC Infectious Diseases 2019 19:366
    Content type: Research article Published on:

  34. Tuberculosis (TB) is an important public health issue worldwide. However, evidence concerning the impact of environmental factors on TB is sparse. We performed a retrospective analysis to determine the spatiot...

    Authors: Xuemei Wang, Shaohua Yin, Yunpeng Li, Wenrui Wang, Maolin Du, Weidong Guo, Mingming Xue, Jing Wu, Danyan Liang, Ruiqi Wang, Dan Liu and Di Chu
    Citation: BMC Infectious Diseases 2019 19:365
    Content type: Research article Published on:

  35. Whilst previous work has identified clustering of the active trachoma sign “trachomatous inflammation—follicular” (TF), there is limited understanding of the spatial structure of trachomatous trichiasis (TT), ...

    Authors: Rebecca Mann Flueckiger, Emanuele Giorgi, Jorge Cano, Mariamo Abdala, Olga Nelson Amiel, Gilbert Baayenda, Ana Bakhtiari, Wilfrid Batcho, Kamal Hashim Bennawi, Michael Dejene, Balgesa Elkheir Elshafie, Aba Ange Elvis, Missamou François, André Goepogui, Khumbo Kalua, Biruck Kebede…
    Citation: BMC Infectious Diseases 2019 19:364
    Content type: Research article Published on:

  36. Hepatitis B virus (HBV) reactivation is one of the most common precipitating events associated with acute decompensation (AD) or acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB)-related cirrh...

    Authors: Jian-Hua Lei, Feng Peng, Zi Chen and Xin-Qiang Xiao
    Citation: BMC Infectious Diseases 2019 19:363
    Content type: Research article Published on:

  37. Ischemic stroke is a common complication in patients with tuberculous meningitis (TBM), which is associated with poor clinical outcome. However, risk factors of stroke in TBM patients were not fully understood...

    Authors: Liming Zhang, Xiaoyu Zhang, Huaqiang Li, Gang Chen and Meijia Zhu
    Citation: BMC Infectious Diseases 2019 19:362
    Content type: Research article Published on:

  38. Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that is widely identified worldwide. This study aimed to investigate the phenotypic characterization and molecular typing of Clostridium difficile is...

    Authors: Parisa Shoaei, Hasan Shojaei, Mohammad Jalali, Farzin Khorvash, Sayed Mohsen Hosseini, Behrooz Ataei, Bahareh Vakili, Fatemeh Ebrahimi, Hossein Tavakoli, Zahra Esfandiari and J. Scott Weese
    Citation: BMC Infectious Diseases 2019 19:361
    Content type: Research article Published on:

  39. Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. The disease affects all ages and both sexes but more prevalent among the sexually active age group of 15–49 years. The purp...

    Authors: Martin Banong-le, Samuel Kwabena Ofosu and Francis Anto
    Citation: BMC Infectious Diseases 2019 19:360
    Content type: Research article Published on:

  40. Pro-inflammatory cytokines expressed in human immune deficiency virus (HIV) infection, may induce oxidative stress likely to compromise the patency of the airways or damage the lung tissues/cardiac function. H...

    Authors: S. C. Ibeneme, C. Omeje, H. Myezwa, Salome Nwaelom Ezeofor, E. M. Anieto, F. Irem, Amaka Obiageli Nnamani, Fortune Elochukwu Ezenwankwo and G. C. Ibeneme
    Citation: BMC Infectious Diseases 2019 19:359
    Content type: Research article Published on:

  41. Necrotizing fasciitis is a deep infection of the fascia and subcutaneous tissue with a high mortality rate. Meningitis is an infection of the membranes surrounding the brain with a likewise high mortality rate. S...

    Authors: Nichlas Hovmand, Sarah Byberg, Morten Bo Larsen, Daria Podlekareva, David Levarett Buck and Birgitte Rønde Hansen
    Citation: BMC Infectious Diseases 2019 19:358
    Content type: Case report Published on:

  42. Overcrowding, reduced nurse to patient ratio, limited distance between incubators and absence of microbiological surveillance have been shown to promote spread of multidrug-resistant gram-negative organisms (M...

    Authors: Doris Fischer, Rolf L. Schlößer, Volkhard A. J. Kempf, Thomas A. Wichelhaus, Thomas Klingebiel, Sabine Philippi, Linda Falgenhauer, Can Imirzalioglu, Udo Dahl, Christian Brandt and Claudia Reinheimer
    Citation: BMC Infectious Diseases 2019 19:357
    Content type: Research article Published on:

  43. Varicella during pregnancy can lead to serious maternal and fetal consequences. Although an effective vaccine is available it is not incorporated in to the routine vaccination programs in most of the Asian cou...

    Authors: Ishara P. Premathilake, Praveena Aluthbaduge, Channa P. Senanayake, Renuka Jayalatharachchi, Sirithilak Gamage and Jude Jayamaha
    Citation: BMC Infectious Diseases 2019 19:356
    Content type: Research article Published on:

  44. Cleaning and disinfection processes must be improved so that there is a reduction in environmental contamination of frequent-contact surfaces. The objective of this study was to evaluate cleaning and disinfect...

    Authors: Mara Cristina Ribeiro Furlan, Adriano Menis Ferreira, Larissa da Silva Barcelos, Marcelo Alessandro Rigotti, Alvaro Francisco Lopes de Sousa, Aires Garcia dos Santos Junior, Denise de Andrade, Margarete Teresa Gottardo de Almeida and Mayckel da Silva Barreto
    Citation: BMC Infectious Diseases 2019 19:355
    Content type: Research article Published on:

  45. Quinine (QN) remains an effective drug for malaria treatment. However, quinine resistance (QNR) in Plasmodium falciparum has been reported in many malaria-endemic regions particularly in African countries. Geneti...

    Authors: Kai Wu, Yi Yao, Fang Chen, Mingxing Xu, Guangquan Lu, Tingting Jiang, Ziyu Liu, Weixing Du, Fang Li, Rugui Li, Huabing Tan and Jian Li
    Citation: BMC Infectious Diseases 2019 19:354
    Content type: Research article Published on:

  46. In developing countries particularly in sub-Saharan Africa trachoma is still a public health concern. Ethiopia is the most affected of all and bears the highest burden of active trachoma. In spite of this, the...

    Authors: Kemal Kassim, Jeylan Kassim, Rameto Aman, Mohammedawel Abduku, Mekonnen Tegegne and Biniyam Sahiledengle
    Citation: BMC Infectious Diseases 2019 19:353
    Content type: Research article Published on:

  47. Middle East respiratory syndrome coronavirus (MERS-CoV) is considered to be responsible for a new viral epidemic and an emergent threat to global health security. This study describes the current epidemiologic...

    Authors: Kazhal Mobaraki and Jamal Ahmadzadeh
    Citation: BMC Infectious Diseases 2019 19:351
    Content type: Research article Published on:

  48. The geographical distribution of intestinal parasites with conditions of poverty in most countries of sub-Saharan Africa coincides with that of HIV/AIDS. However, there is paucity of studies investigating the ...

    Authors: Tuom Gebrewahid, Gebretsadkan Gebrekirstos, Mebrahtu Teweldemedhin, Hailay Gebreyesus, Abrham Awala and Kiros Tadla
    Citation: BMC Infectious Diseases 2019 19:350
    Content type: Research article Published on:

  49. Although prior hospitalization (PH) has been considered as a risk factor for infection with potentially drug-resistant (PDR) pathogens in patients admitted with pneumonia, the evidence is limited. We aimed to ...

    Authors: Jae-Uk Song, Yee Hyung Kim, Mi Yeon Lee and Jonghoo Lee
    Citation: BMC Infectious Diseases 2019 19:349
    Content type: Research article Published on:

  50. Pooling sputum specimens is one potential strategy for reducing the cost of using Xpert MTB/RIF, a rapid polymerase chain reaction (PCR)-based test, for the diagnosis of pulmonary tuberculosis. We sought to co...

    Authors: Nguyen Thi Bich Phuong, Nguyen Thu Anh, Nguyen Van Son, Vitali Sintchenko, Jennifer Ho, Greg J. Fox, Nguyen Viet Nhung and Guy B. Marks
    Citation: BMC Infectious Diseases 2019 19:347
    Content type: Technical advance Published on:

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