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  1. Approximately 7% of survivors from meningococcal meningitis (MM) suffer from neurological sequelae due to brain damage in the course of meningitis. The present study focuses on the role of matrix metalloprotei...

    Authors: Susanna Ricci, Denis Grandgirard, Michael Wenzel, Tiziana Braccini, Paola Salvatore, Marco R Oggioni, Stephen L Leib and Uwe Koedel
    Citation: BMC Infectious Diseases 2014 14:726
    Content type: Research article Published on:

  2. HIV increasingly is experienced as a complex chronic illness where individuals are living longer with a range of physical, cognitive, mental and social health-related challenges associated with HIV, comorbidit...

    Authors: Kelly K O’Brien, Francisco Ibáñez-Carrasco, Patricia Solomon, Richard Harding, Jessica Cattaneo, William Chegwidden, Jacqueline Gahagan, Larry Baxter, Catherine Worthington, Patriic Gayle, Brenda Merritt, Rosalind Baltzer-Turje, Nkem Iku and Elisse Zack
    Citation: BMC Infectious Diseases 2014 14:724
    Content type: Research article Published on:

  4. Few data exist on the use of text messaging as a tool to promote retention in HIV care and virologic suppression at the clinic level in the United States. We describe the protocol for a study designed to inves...

    Authors: Katerina A Christopoulos, Elise D Riley, Jacqueline Tulsky, Adam W Carrico, Judith T Moskowitz, Leslie Wilson, Lara S Coffin, Veesta Falahati, Jordan Akerley and Joan F Hilton
    Citation: BMC Infectious Diseases 2014 14:718
    Content type: Study protocol Published on:

  5. Among methods for preventing pneumonia and possibly also bacteremia in intensive care unit (ICU) patients, Selective Digestive Decontamination (SDD) appears most effective within randomized concurrent controll...

    Authors: James C Hurley
    Citation: BMC Infectious Diseases 2014 14:714
    Content type: Research article Published on:

  6. Although the evidence base regarding the use of the Xpert MTB/RIF assay for diagnosis of pulmonary tuberculosis (TB) when testing respiratory samples is well established, the evidence base for its diagnostic a...

    Authors: Laura Maynard-Smith, Natasha Larke, Jurgens A Peters and Stephen D Lawn
    Citation: BMC Infectious Diseases 2014 14:709
    Content type: Research article Published on:

  7. A total of 453 laboratory-confirmed cases infected with avian influenza A (H7N9) virus (including 175 deaths) have been reported till October 2,2014, of which 30.68% (139/453) of the cases were identified from...

    Authors: Hua Ding, Yin Chen, Zhao Yu, Peter W Horby, Fenjuan Wang, Jingfeng Hu, Xuhui Yang, Haiyan Mao, Shuwen Qin, Chengliang Chai, Shelan Liu, Enfu Chen and Hongjie Yu
    Citation: BMC Infectious Diseases 2014 14:698
    Content type: Research article Published on:

  9. Internet-based surveillance systems provide a novel approach to monitoring infectious diseases. Surveillance systems built on internet data are economically, logistically and epidemiologically appealing and ha...

    Authors: Gabriel J Milinovich, Simon M R Avril, Archie C A Clements, John S Brownstein, Shilu Tong and Wenbiao Hu
    Citation: BMC Infectious Diseases 2014 14:690
    Content type: Research article Published on:

  10. Our aim was to compare the 12-month incidence and clearance of oral high-risk HPV infection between HIV-infected men who have sex with men (MSM) and HIV-negative MSM.

    Authors: Fleur van Aar, Sofie H Mooij, Marianne AB van der Sande, Chris JLM Meijer, Audrey J King, Dominique WM Verhagen, Titia Heijman, Roel A Coutinho and Maarten F Schim van der Loeff
    Citation: BMC Infectious Diseases 2014 14:668
    Content type: Research article Published on:

  11. Variations at DEPDC5 gene have been recently reported as genetic markers associated with hepatocellular carcinoma (HCC) progression in chronic HCV-infected patients. This study was conducted to assess the asso...

    Authors: Mashael R Al-Anazi, Sabine Matou-Nasri, Ayman A Abdo, Faisal M Sanai, Mohammed Q Khan, Ali Albenmousa, Hamad I Al-Ashgar, Nisreen Z Khalaf, Mohammed N Al-Ahdal and Ahmed A Al-Qahtani
    Citation: BMC Infectious Diseases 2014 14:632
    Content type: Research article Published on:

  12. Antimicrobial resistance of Neisseria gonorrhoeae is a serious health problem in China. Gonococcal antimicrobial susceptibility has been monitored in Shanghai since 1988. In this study, we examined the changing p...

    Authors: Wei-Ming Gu, Yue Chen, Yang Yang, Lei Wu, Wei-Zhong Hu and Yue-Lan Jin
    Citation: BMC Infectious Diseases 2014 14:731
    Content type: Research article Published on:

  13. Spontaneous bacterial peritonitis (SBP) is a rare affection in the pediatric population. It usually occurs when concurrent conditions are present, such as nephrotic syndrome, peritoneal dialysis or liver disea...

    Authors: Gabriel Brändle, Arnaud G L’Huillier, Noémie Wagner, Alain Gervaix, Barbara E Wildhaber and Laurence Lacroix
    Citation: BMC Infectious Diseases 2014 14:719
    Content type: Case report Published on:

  14. Colorectal cancer (CRC) is the 3rd most common cancer worldwide and the Czech Republic has the 6th highest incidence of CRC worldwide. Large intestinal microbiota play in its etiopathogenesis important role. B...

    Authors: Darina Kohoutova, David Smajs, Paula Moravkova, Jiri Cyrany, Monika Moravkova, Miroslava Forstlova, Michal Cihak, Stanislav Rejchrt and Jan Bures
    Citation: BMC Infectious Diseases 2014 14:733
    Content type: Research article Published on:

  15. With the advent of highly active antiretroviral therapy (HAART), HIV infection has become a chronic condition in children with improved survival and quality of life. Reports on long term effectiveness of non-n...

    Authors: Aparna Mukherjee, Nipam Shah, Ravinder Singh, Madhu Vajpayee, Sushil K Kabra and Rakesh Lodha
    Citation: BMC Infectious Diseases 2014 14:701
    Content type: Research article Published on:

  16. Antiretroviral therapy (ART) in pregnancy has resulted in a marked impact on reducing the risk of mother-to-child transmission (MCT) of HIV. However the safety of in utero ART exposure in newborns remains a co...

    Authors: Luis M Prieto, María Isabel González- Tomé, Eloy Muñoz, María Fernández-Ibieta, Beatriz Soto, Ana Álvarez, Maria Luisa Navarro, Miguel Ángel Roa, José Beceiro, María Isabel de José, Iciar Olabarrieta, David Lora and José Tomás Ramos
    Citation: BMC Infectious Diseases 2014 14:700
    Content type: Research article Published on:

  17. Although severe sepsis constitutes an important burden for healthcare systems, there is limited nationwide data on its epidemiology in European countries. Our objective was to examine the most recent epidemiol...

    Authors: Carmen Bouza, Teresa López-Cuadrado, Zuleika Saz-Parkinson and José María Amate-Blanco
    Citation: BMC Infectious Diseases 2014 14:3863
    Content type: Research article Published on:

  18. Australia commenced human papillomavirus (HPV) vaccination in 2007, with a two-year catch-up to the age of 26; catch-up cohorts are thus now entering their thirties. Plans for monitoring vaccine impact involve...

    Authors: Louiza S Velentzis, Freddy Sitas, Dianne L O’Connell, Jessica Darlington-Brown, Sam Egger, Rohit Sinha, Emily Banks, Ian H Frazer and Karen Canfell
    Citation: BMC Infectious Diseases 2014 14:3861
    Content type: Research article Published on:

  19. Anaemia is frequently associated with both HIV-infection and HIV-related tuberculosis (TB) in antiretroviral therapy (ART)-naïve patients in sub-Saharan Africa and is strongly associated with poor prognosis. H...

    Authors: Andrew D Kerkhoff, Robin Wood, Frank G Cobelens, Ankur Gupta-Wright, Linda-Gail Bekker and Stephen D Lawn
    Citation: BMC Infectious Diseases 2014 14:3860
    Content type: Research article Published on:

  20. Tuberculosis (TB) mortality remains high across sub-Saharan Africa despite integration of TB and HIV/ART programmes. To inform programme design and service delivery, we estimated mortality by time from startin...

    Authors: Nigel Field, Megan SC Lim, Jill Murray, Robert J Dowdeswell, Judith R Glynn and Pam Sonnenberg
    Citation: BMC Infectious Diseases 2014 14:3858
    Content type: Research article Published on:

  21. Despite the clinical significance of Salmonella infections, surveillance data worldwide remains limited and is more so exemplified by the lack of reports from Africa especially in eastern, central and western Afr...

    Authors: Appiah-Korang Labi, Noah Obeng-Nkrumah, Naa Okaikor Addison and Eric Sampene Donkor
    Citation: BMC Infectious Diseases 2014 14:3857
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Infectious Diseases 2015 15:263

  22. Genes related to antigen presentation pathway, which are in the non-classical class-II region of human leukocyte antigen (HLA), play a vital role during the infection of hepatitis C virus (HCV).

    Authors: Peng Huang, Li Dong, Xiaomei Lu, Yuanyuan Zhang, Hongbo Chen, Jie Wang, Yun Zhang, Jing Su and Rongbin Yu
    Citation: BMC Infectious Diseases 2014 14:716
    Content type: Research article Published on:

  24. Toxoplasmosis caused by the intracellular parasite Toxoplasma gondii (T. gondii) is a global epidemic parasitic disease. DNA vaccines play an important role in preventing the spread of toxoplasmosis. SAG family g...

    Authors: Gang Lu, Aihua Zhou, Min Meng, Lin Wang, Yali Han, Jingjing Guo, Huaiyu Zhou, Hua Cong, Qunli Zhao, Xing-Quan Zhu and Shenyi He
    Citation: BMC Infectious Diseases 2014 14:3862
    Content type: Research article Published on:

  25. The burden of bloodstream infections is insufficiently studied in children in Africa and many healthcare facilities lack the capacity to identify invasive disease. Often studies have been limited to febrile pa...

    Authors: Joakim Isendahl, Cristovão Manjuba, Amabelia Rodrigues, Weiping Xu, Birgitta Henriques-Normark, Christian G Giske and Pontus Nauclér
    Citation: BMC Infectious Diseases 2014 14:3859
    Content type: Research article Published on:

  26. Acute invasive fungal rhinosinusitis is a lethal infectious process afflicting immunocompromised individuals. Knowledge about this disease is still limited due to the scarcity of animal models designed to stud...

    Authors: Yuyan Yan, Zuotao Zhao, Hongfei Wan, Ruochen Wu, Jugao Fang and Honggang Liu
    Citation: BMC Infectious Diseases 2014 14:3856
    Content type: Research article Published on:

  27. The influence of environmental and climatic factors on malaria vector bionomics and transmission is an important topic in the context of climatic change particularly at macro-geographical level. Sahelian areas...

    Authors: El Hadji Malick Ngom, Ndèye Diango Faye, Cheikh Talla, El Hadji Ndiaye, Jacques-André Ndione, Ousmane Faye, Yamar Ba, Mawlouth Diallo and Ibrahima Dia
    Citation: BMC Infectious Diseases 2014 14:3838
    Content type: Research article Published on:

  28. Human papillomavirus (HPV) infection is the main etiological factor for cervical cancer and premalignant lesions of the cervix. The purposes of the present study were to determine the prevalence of type-specif...

    Authors: Xiao-Xiang Liu, Xing-Li Fan, Yue-Ping Yu, Lei Ji, Jie Yan and Ai-Hua Sun
    Citation: BMC Infectious Diseases 2014 14:708
    Content type: Research article Published on:

  29. People who inject drugs (PWID) are a key population affected by HIV. We assessed the effectiveness of HIV treatment among a clinical cohort of people living with HIV (PLHIV) diagnosed and referred for communit...

    Authors: Nick Walsh, Anne Mijch, Kerrie Watson, Handan Wand, Christopher K Fairley, John McNeil, Nick Crofts and Lisa Maher
    Citation: BMC Infectious Diseases 2014 14:707
    Content type: Research article Published on:

  30. It is debated whether interferon-based therapy (IBT) would affect the incidence of active tuberculosis (TB) among hepatitis C virus (HCV) infected patients. Although some case reports have demonstrated a possi...

    Authors: Shang-Yi Lin, Tun-Chieh Chen, Po-Liang Lu, Chun-Yu Lin, Wei-Ru Lin, Yi-Hsin Yang and Yen-Hsu Chen
    Citation: BMC Infectious Diseases 2014 14:705
    Content type: Research article Published on:

  32. The global increase in the burden of multidrug-resistant tuberculosis (MDR-TB) underscores an urgent need for data on factors involved in generation and spread of TB drug resistance. We performed molecular ana...

    Authors: Nicholas Ezati, Deus Lukoye, Eddie M Wampande, Kenneth Musisi, George W Kasule, Frank GJ Cobelens, David P Kateete and Moses L Joloba
    Citation: BMC Infectious Diseases 2014 14:703
    Content type: Research article Published on:

  33. World-wide, the notable expansion of HIV/AIDS treatment programs in resource-limited settings has lead to an increasing number of patients in need of second-line cART. To adequately address and prepare for thi...

    Authors: Sandra W Cardoso, Paula M Luz, Luciane Velasque, Thiago S Torres, Isabel C Tavares, Sayonara R Ribeiro, Ronaldo I Moreira, Valdilea G Veloso, Richard D Moore and Beatriz Grinsztejn
    Citation: BMC Infectious Diseases 2014 14:699
    Content type: Research article Published on:

  34. China experiencing an increasing HIV epidemic among men who have sex with men (MSM), and unprotected anal intercourse (UAI) has played a key role in this process. The aims of this study were to examine the tre...

    Authors: Weibin Cheng, Weiming Tang, Fei Zhong, Giridhar R Babu, Zhigang Han, Faju Qin, Kai Gao, Huixia Mai, Yuteng Zhao, Caiyun Liang, Lirui Fan, Hao Wu, Huifang Xu and Ming Wang
    Citation: BMC Infectious Diseases 2014 14:696
    Content type: Research article Published on:

  35. Detection of fungal DNA from formalin-fixed, paraffin-embedded (FFPE) tissue is challenging due to degradation of DNA and presence of PCR inhibitors in these samples. We analyzed FFPE samples of 26 patients by...

    Authors: B Babouee Flury, M Weisser, S Savič Prince, L Bubendorf, M Battegay, R Frei and D Goldenberger
    Citation: BMC Infectious Diseases 2014 14:692
    Content type: Research article Published on:

  36. In Norway, it is recommended that children with Shiga-Toxin producing Escherichia coli (STEC) infections are excluded from daycare centers until up to five consecutive negative stool cultures are obtained. Childr...

    Authors: Emily MacDonald, Per Kjetil Dalane, Preben Aavitsland, Lin Thorstensen Brandal, Astrid Louise Wester and Line Vold
    Citation: BMC Infectious Diseases 2014 14:673
    Content type: Research article Published on:

  37. Although uncomplicated cystitis is often self-limiting, most such patients will be prescribed antibiotic treatment. We are investigating whether treatment of cystitis with an NSAID is as effective as an antibi...

    Authors: Ingvild Vik, Marianne Bollestad, Nils Grude, Anders Bærheim, Sigvard Mölstad, Lars Bjerrum and Morten Lindbæk
    Citation: BMC Infectious Diseases 2014 14:693
    Content type: Study protocol Published on:

  38. Interferon-γ release assays (IGRA) serve as immunodiagnostics of tuberculosis (TB) infection to identify individuals with latent TB infection (LTBI) eligible for preventive anti-TB therapy. In this longitudina...

    Authors: Nadine Durema Pullar, Harald Steinum, Johan Nikolai Bruun and Anne Ma Dyrhol-Riise
    Citation: BMC Infectious Diseases 2014 14:667
    Content type: Research article Published on:

  39. Influenza and respiratory syncytial virus (RSV) infection are common causes of lower respiratory tract illness. Data on their burden in low and middle-income settings and from Africa are scarce. We aimed to es...

    Authors: Robert Kyeyagalire, Stefano Tempia, Adam L Cohen, Adrian D Smith, Johanna M McAnerney, Veerle Dermaux-Msimang and Cheryl Cohen
    Citation: BMC Infectious Diseases 2014 14:694
    Content type: Research article Published on:

  40. Transmitted drug resistance (TDR) is an important public health issue, because TDR-associated mutation may affect the outcome of antiretroviral treatment potentially or directly. Men who have sex with men (MSM...

    Authors: Yang Jiao, Shuming Li, Zhenpeng Li, Zheng Zhang, Jianhong Zhao, Li Li, Lijuan Wang, Qianqian Yin, Yan Wang, Zhaoli Zeng, Yiming Shao and Liying Ma
    Citation: BMC Infectious Diseases 2014 14:689
    Content type: Research article Published on:

  41. Rickettsia felis is a recently described flea-borne spotted fever group Rickettsia that is an emerging human pathogen. Although there is information on the organism from around the world, there is no information...

    Authors: Jilei Zhang, Guangwu Lu, Patrick Kelly, Zhenwen Zhang, Lanjing Wei, Duonan Yu, Shayilan Kayizha and Chengming Wang
    Citation: BMC Infectious Diseases 2014 14:682
    Content type: Research article Published on:

  42. Prison conditions can favor the spread of tuberculosis (TB). This study aimed to evaluate in a Brazilian prison: the performance and accuracy of smear, culture and Detect-TB; performance of smear plus culture ...

    Authors: Karen Barros Schmid, Luciene Scherer, Regina Bones Barcellos, Daniele Kuhleis, Isaías Valente Prestes, Ricardo Ewbank Steffen, Elis Regina Dalla Costa and Maria Lucia Rosa Rossetti
    Citation: BMC Infectious Diseases 2014 14:678
    Content type: Research article Published on:

  43. Anal cancer has become one of the most common non-AIDS-defined tumors among Human Immunodeficiency Virus-positive (HIV+) individuals, and a rise in its incidence among HIV+ Men who have Sex with Men (MSM) has ...

    Authors: Rocío Méndez-Martínez, Norma E Rivera-Martínez, Brenda Crabtree-Ramírez, Juan G Sierra-Madero, Yanink Caro-Vega, Silvia C Galván, David Cantú de León and Alejandro García-Carrancá
    Citation: BMC Infectious Diseases 2014 14:671
    Content type: Research article Published on:

  44. Staphylococcus aureus (S.aureus) is a major cause of both healthcare and community acquired infections. In developing countries, manual phenotypic tests are the mainstay for the identification of staphylococci w...

    Authors: Geoffrey Omuse, Beatrice Kabera and Gunturu Revathi
    Citation: BMC Infectious Diseases 2014 14:669
    Content type: Research article Published on:

  45. The objective of this study was to describe the clinical and microbiological characteristics of bloodstream infections (BSIs) due to AmpC producing Enterobacteriaceae (AE) in a large centralized Canadian regio...

    Authors: Vikas P Chaubey, Johann D D Pitout, Bruce Dalton, Daniel B Gregson, Terry Ross and Kevin B Laupland
    Citation: BMC Infectious Diseases 2014 14:647
    Content type: Research article Published on:

  46. Cervical cancer (CC) is caused by persistent infection with high-risk (HR) human papillomavirus (HPV) types. In Saudi Arabia which has a population of 6.5 million women over the age of 15 years, approximately ...

    Authors: Abdulaziz AlObaid, Ismail A Al-Badawi, Hanan Al-Kadri, Kusuma Gopala, Walid Kandeil, Wim Quint, Murad Al-Aker and Rodrigo DeAntonio
    Citation: BMC Infectious Diseases 2014 14:643
    Content type: Research article Published on:

  47. Linezolid, which has bacteriostatic activity, is approved for the treatment of vancomycin-resistant enterococci (VRE) infections. Meanwhile, daptomycin exerts bactericidal activity against VRE, but is not appr...

    Authors: Yu-Chung Chuang, Jann-Tay Wang, Hsin-Yi Lin and Shan-Chwen Chang
    Citation: BMC Infectious Diseases 2014 14:687
    Content type: Research article Published on:

  48. The HIV co-receptors CXCR4 and CCR5 play an important role in HIV infection and replication. Therefore we hypothesize that long-term non-progressors (LTNP) with viral control have lower expression of CCR5 and ...

    Authors: Hinta Meijerink, Agnes R Indrati, Reinout van Crevel, Irma Joosten, Hans Koenen and Andre JAM van der Ven
    Citation: BMC Infectious Diseases 2014 14:683
    Content type: Research article Published on:

  49. Chest-x-ray is routinely used in the diagnosis of smear negative tuberculosis (TB). This study assesses the incremental cost per true positive test of a point-of-care digital chest-x-ray, in the diagnosis of p...

    Authors: Gambo Aliyu, Samer S El-Kamary, Alash’le Abimiku, Laura Hungerford, Joshua Obasanya and William Blattner
    Citation: BMC Infectious Diseases 2014 14:675
    Content type: Research article Published on:

  50. Once considered primarily a pediatric concern, respiratory syncytial virus (RSV) infection is gaining recognition as a cause of significant morbidity and mortality in adults. A better understanding of RSV epid...

    Authors: Cheryl Volling, Kazi Hassan, Tony Mazzulli, Karen Green, Ahmed Al-Den, Paul Hunter, Rupi Mangat, John Ng and Allison McGeer
    Citation: BMC Infectious Diseases 2014 14:665
    Content type: Research article Published on:

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