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  1. Febrile neutropenia carries a high risk of sepsis complications, and the identification of biomarkers capable to identify high risk patients is a great challenge. Angiopoietins (Ang -) are cytokines involved i...

    Authors: Brunna E Alves, Silmara AL Montalvao, Franciso JP Aranha, Tania FG Siegl, Carmino A Souza, Irene Lorand-Metze, Joyce M Annichino-Bizzacchi and Erich V De Paula
    Citation: BMC Infectious Diseases 2010 10:143
    Content type: Research article Published on:

  2. Dengue is a major public health problem in tropical and subtropical countries. Rapid and easy diagnosis of dengue can assist patient triage and care-management. The detection of DENV NS1 on rapid lateral flow ...

    Authors: Vianney Tricou, Hang TT Vu, Nhu VN Quynh, Chau VV Nguyen, Hien T Tran, Jeremy Farrar, Bridget Wills and Cameron P Simmons
    Citation: BMC Infectious Diseases 2010 10:142
    Content type: Research article Published on:

  3. The detailed analysis of an outbreak database has been undertaken to examine the role of contact tracing in controlling an outbreak of possible avian influenza in humans. The outbreak, initiating from the purc...

    Authors: Ken TD Eames, Cerian Webb, Kathrin Thomas, Josie Smith, Roland Salmon and J Mark F Temple
    Citation: BMC Infectious Diseases 2010 10:141
    Content type: Research article Published on:

  4. During the SARS pandemic in Hong Kong, panic and worry were prevalent in the community and the general public avoided staying in public areas. Such avoidance behaviors could greatly impact daily routines of th...

    Authors: Joseph TF Lau, Sian Griffiths, Kai Chow Choi and Hi Yi Tsui
    Citation: BMC Infectious Diseases 2010 10:139
    Content type: Research article Published on:

  5. Recent interest has focused on the potential use of serial interferon gamma (IFN-γ) release assay (IGRA) measurements to assess the response to anti-tuberculous (TB) treatment. The kinetics of IFN-γ responses to

    Authors: Tom G Connell, Mary-Ann Davies, Christine Johannisen, Kathryn Wood, Sandy Pienaar, Katalin A Wilkinson, Robert J Wilkinson, Heather J Zar, David Beatty, Mark P Nicol, Nigel Curtis and Brian Eley
    Citation: BMC Infectious Diseases 2010 10:138
    Content type: Research article Published on:

  6. The objective of this study was to estimate the effect of male circumcision (MC) on HIV acquisition estimated using HIV incidence assays and to compare it to the effect measured by survival analysis.

    Authors: Agnès Fiamma, Pascale Lissouba, Oliver E Amy, Beverley Singh, Oliver Laeyendecker, Thomas C Quinn, Dirk Taljaard and Bertran Auvert
    Citation: BMC Infectious Diseases 2010 10:137
    Content type: Research article Published on:

  7. In infectious disease surveillance, when the laboratory confirmation of the cases is time-consuming, there is often a time lag between the number of suspect cases and the number of confirmed cases. This study ...

    Authors: Pei-Hung Chuang, Jen-Hsiang Chuang and I-Feng Lin
    Citation: BMC Infectious Diseases 2010 10:136
    Content type: Research article Published on:

  8. Bloodstream Infections (BSIs) in neutropenic patients often cause considerable morbidity and mortality. Therefore, the surveillance and early identification of patients at high risk for developing BSIs might b...

    Authors: Eleni Apostolopoulou, Vasilios Raftopoulos, Konstantinos Terzis and Ioannis Elefsiniotis
    Citation: BMC Infectious Diseases 2010 10:135
    Content type: Research article Published on:

  9. Although seasonal influenza vaccine is effective in the elderly, immune responses to vaccination are lower in the elderly than in younger adults. Strategies to optimise responses to vaccination in the elderly ...

    Authors: Pierre Van Damme, Robert Arnou, Froukje Kafeja, Anne Fiquet, Patrick Richard, Stéphane Thomas, Gilles Meghlaoui, Sandrine Isabelle Samson and Emilio Ledesma
    Citation: BMC Infectious Diseases 2010 10:134
    Content type: Research article Published on:

  10. Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA), is an important cause of pyogenic skin and soft tissue infections (SSTIs). The aim of present study is to investigate the molecular cha...

    Authors: Dan Yao, Fang-you Yu, Zhi-qiang Qin, Chun Chen, Su-su He, Zeng-qiang Chen, Xue-qing Zhang and Liang-xing Wang
    Citation: BMC Infectious Diseases 2010 10:133
    Content type: Research article Published on:

  11. Nephropathia epidemica (NE) is a Scandinavian type of hemorrhagic fever with renal syndrome caused by Puumala hantavirus. The clinical course of the disease varies greatly in severity. The aim of the present s...

    Authors: Tuula K Outinen, Satu M Mäkelä, Ilpo O Ala-Houhala, Heini SA Huhtala, Mikko Hurme, Antti S Paakkala, Ilkka H Pörsti, Jaana T Syrjänen and Jukka T Mustonen
    Citation: BMC Infectious Diseases 2010 10:132
    Content type: Research article Published on:

  13. Community acquired Bacterial Meningitis (BM) remains a serious threat to global health. Cuban surveillance system for BM allowed to characterize the main epidemiological features of this group of diseases, as ...

    Authors: Antonio E Pérez, Félix O Dickinson and Misladys Rodríguez
    Citation: BMC Infectious Diseases 2010 10:130
    Content type: Research article Published on:

  14. Effective highly active antiretroviral therapy (HAART) reduces human immunodeficiency virus (HIV) replication, restores CD4+ T lymphocyte counts and greatly reduces the incidence of opportunistic infections. Whil...

    Authors: Julia Pohling, Katrin Zipperlen, Natasha A Hollett, Maureen E Gallant and Michael D Grant
    Citation: BMC Infectious Diseases 2010 10:129
    Content type: Research article Published on:

  15. The ecology of influenza may be more complex than is usually assumed. For example, despite multiple waves in the influenza pandemic of 1918-19, many people in urban locations were apparently unaffected. Were t...

    Authors: John D Mathews, Emma S McBryde, Jodie McVernon, Paul K Pallaghy and James M McCaw
    Citation: BMC Infectious Diseases 2010 10:128
    Content type: Research article Published on:

  16. Sexually transmitted infections (STIs) and Reproductive tract infections (RTIs) are responsible for high morbidity among women. We aim to quantify the magnitude of the burden and risk factors of STI/RTI s amon...

    Authors: Nyaradzai E Kurewa, Munyaradzi P Mapingure, Marshal W Munjoma, Mike Z Chirenje, Simbarashe Rusakaniko and Babill Stray-Pedersen
    Citation: BMC Infectious Diseases 2010 10:127
    Content type: Research article Published on:

  17. Risk of pneumocystosis after discontinuation of primary or secondary prophylaxis among HIV-infected patients before CD4 counts increase to ≧200 cells/μL (early discontinuation) after receiving highly active an...

    Authors: Chien-Yu Cheng, Mao-Yuan Chen, Szu-Min Hsieh, Wang-Huei Sheng, Hsin-Yun Sun, Yi-Chun Lo, Wen-Chun Liu and Chien-Ching Hung
    Citation: BMC Infectious Diseases 2010 10:126
    Content type: Research article Published on:

  18. PCR amplification for the detection of pathogens in biological material is generally considered a rapid and informative diagnostic technique. Invasive Salmonella serovars, which cause enteric fever, can be common...

    Authors: Tran Vu Thieu Nga, Abhilasha Karkey, Sabina Dongol, Hang Nguyen Thuy, Sarah Dunstan, Kathryn Holt, Le Thi Phuong Tu, James I Campbell, Tran Thuy Chau, Nguyen Van Vinh Chau, Amit Arjyal, Samir Koirala, Buddha Basnyat, Christiane Dolecek, Jeremy Farrar and Stephen Baker
    Citation: BMC Infectious Diseases 2010 10:125
    Content type: Research article Published on:

  19. Legionella is a common cause of bacterial pneumonia. Community-acquired [CAL] and hospital-acquired legionellosis [HAL] may have different presentations and outcome. We aimed to compare clinical characteristic...

    Authors: Sanne Jespersen, Ole S Søgaard, Henrik C Schønheyder, Michael J Fine and Lars Østergaard
    Citation: BMC Infectious Diseases 2010 10:124
    Content type: Research article Published on:

  20. Over the past several years, new diagnostic techniques have been developed to allow for the rapid detection of multidrug resistant tuberculosis. The GenoType® MTBDRplus test is a deoxyribonucleic acid (DNA) strip...

    Authors: Rapeepun Anek-vorapong, Chalinthorn Sinthuwattanawibool, Laura Jean Podewils, Kimberly McCarthy, Keerataya Ngamlert, Busakorn Promsarin and Jay K Varma
    Citation: BMC Infectious Diseases 2010 10:123
    Content type: Research article Published on:

  21. Yersinia enterocolitica (YE) is the causative agent of yersiniosis. YE encompass strains of diverse pathogenicity: YE biotypes 1B and 2-5 are considered pathogenic, whereas biotype 1A is in general considered no...

    Authors: Elisa Huovinen, Leila M Sihvonen, Mikko J Virtanen, Kaisa Haukka, Anja Siitonen and Markku Kuusi
    Citation: BMC Infectious Diseases 2010 10:122
    Content type: Research article Published on:

  22. Bartonella infections are emerging in the Zhejiang Province of China. However, there has been no effort to date to explore the epidemiology of these infections in this region, nor to identify risk factors associ...

    Authors: Jimin Sun, Guiming Fu, Junfen Lin, Xiuping Song, Liang Lu and Qiyong Liu
    Citation: BMC Infectious Diseases 2010 10:121
    Content type: Research article Published on:

  23. H2O2 produced by vaginal lactobacilli is believed to protect against infection, and H2O2-producing lactobacilli inactivate pathogens in vitro in protein-free salt solution. However, cervicovaginal fluid (CVF) and...

    Authors: Deirdre E O'Hanlon, Blair R Lanier, Thomas R Moench and Richard A Cone
    Citation: BMC Infectious Diseases 2010 10:120
    Content type: Research article Published on:

  24. Highland areas of Africa are mostly malaria hypoendemic, due to climate which is not appropriate for anophelines development and their reproductive fitness. In view of designing a malaria control strategy in W...

    Authors: Timoléon Tchuinkam, Frédéric Simard, Espérance Lélé-Defo, Billy Téné-Fossog, Aimé Tateng-Ngouateu, Christophe Antonio-Nkondjio, Mbida Mpoame, Jean-Claude Toto, Thomas Njiné, Didier Fontenille and Herman-Parfait Awono-Ambéné
    Citation: BMC Infectious Diseases 2010 10:119
    Content type: Research article Published on:

  25. Species identification of isolates belonging to the Mycobacterium tuberculosis complex (MTC) seems to be important for the appropriate treatment of patients, since M. bovis is naturally resistant to a first line ...

    Authors: Chie Nakajima, Zeaur Rahim, Yukari Fukushima, Isamu Sugawara, Adri GM van der Zanden, Aki Tamaru and Yasuhiko Suzuki
    Citation: BMC Infectious Diseases 2010 10:118
    Content type: Research article Published on:

  26. The adult population in Sri Lanka is having high level of susceptibility for Varicella Zoster Virus (VZV) infection. Among medical undergraduates, 47% are VZV seronegative. The purpose of the present study was...

    Authors: Suneth B Agampodi, Samath D Dharmaratne, Vasanthi Thevanesam, Sameera Dassanayake, Prabhashini Kumarihamy and Ashani Ratnayake
    Citation: BMC Infectious Diseases 2010 10:117
    Content type: Research article Published on:

  27. HIV-monoinfected patients may be at risk for significant liver fibrosis, but its prevalence and determinants in these patients are unknown. Since HIV-monoinfected patients do not routinely undergo liver biopsy...

    Authors: Michelle DallaPiazza, Valerianna K Amorosa, Russell Localio, Jay R Kostman and Vincent Lo Re III
    Citation: BMC Infectious Diseases 2010 10:116
    Content type: Research article Published on:

  28. HHV-8 is closely related to Epstein-Barr virus (EBV), but the clinical presentations of these two infections in early childhood are not well understood. Also, it is not known whether infection by one virus cor...

    Authors: Veenu Minhas, Brad P Brayfield, Kay L Crabtree, Chipepo Kankasa, Charles D Mitchell and Charles Wood
    Citation: BMC Infectious Diseases 2010 10:115
    Content type: Research article Published on:

  29. Avian influenza (AI) is a public health challenge because of ongoing spread and pandemic potential. Non-pharmaceutical measures are important to prevent the spread of AI and to contain a pandemic. The effectiv...

    Authors: Onno de Zwart, Irene K Veldhuijzen, Jan Hendrik Richardus and Johannes Brug
    Citation: BMC Infectious Diseases 2010 10:114
    Content type: Research article Published on:

  30. Influenza A, including avian influenza, is a major public health threat in developed and developing countries. Rapid and accurate detection is a key component of strategies to contain spread of infection, and ...

    Authors: Elektra Szewczuk, Kiran Thapa, Terry Anninos, Kenneth McPhie, Geoff Higgins, Dominic E Dwyer, Keith K Stanley and Jonathan R Iredell
    Citation: BMC Infectious Diseases 2010 10:113
    Content type: Technical advance Published on:

  31. Immune complex deposition is the accepted mechanism of pathogenesis of VL glomerulopathy however other immune elements may participate. Further in the present study, no difference was seen between immunoglobul...

    Authors: Francisco AL Costa, Maria G Prianti, Teresa C Silva, Silvana MMS Silva, José L Guerra and Hiro Goto
    Citation: BMC Infectious Diseases 2010 10:112
    Content type: Research article Published on:

  32. Transfusion-transmissible infectious agents such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis are among the greatest threats to blood safety for the reci...

    Authors: Belay Tessema, Gizachew Yismaw, Afework Kassu, Anteneh Amsalu, Andargachew Mulu, Frank Emmrich and Ulrich Sack
    Citation: BMC Infectious Diseases 2010 10:111
    Content type: Research article Published on:

  33. The incidence of pediatric infections due to community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), including children with no identifiable risk factors, has increased worldwide in the last d...

    Authors: Débora A Tavares, Raquel Sá-Leão, Maria Miragaia and Hermínia de Lencastre
    Citation: BMC Infectious Diseases 2010 10:110
    Content type: Research article Published on:

  34. Since 2003, the Global Fund has supported the scale-up of HIV/AIDS, tuberculosis and malaria control in low- and middle-income countries. This paper presents and discusses a methodology for estimating the live...

    Authors: Ryuichi Komatsu, Eline L Korenromp, Daniel Low-Beer, Catherine Watt, Christopher Dye, Richard W Steketee, Bernard L Nahlen, Rob Lyerla, Jesus M Garcia-Calleja, John Cutler and Bernhard Schwartländer
    Citation: BMC Infectious Diseases 2010 10:109
    Content type: Research article Published on:

  35. Scrub typhus is a mite-borne bacterial infection of humans caused by Orientia tsutsugamushi that causes a generalized vasculitis that may involve the tissues of any organ system. The aim of this study was to iden...

    Authors: Dong-Min Kim, Seok Won Kim, Seong-Hyung Choi and Na Ra Yun
    Citation: BMC Infectious Diseases 2010 10:108
    Content type: Research article Published on:

  36. Healthcare workers are still recognised as a high-risk group for latent TB infection (LTBI). Therefore, the screening of people employed in the healthcare sector for active and LTBI is fundamental to infection...

    Authors: Anja Schablon, Melanie Harling, Roland Diel and Albert Nienhaus
    Citation: BMC Infectious Diseases 2010 10:107
    Content type: Research article Published on:

  38. In recent years, the number of syphilis cases has stabilised in many countries of Western Europe, however several countries have reported increases among men who have sex with men (MSM). The aim of this articl...

    Authors: Irena Jakopanec, Andrej M Grjibovski, Øivind Nilsen and Preben Aavitsland
    Citation: BMC Infectious Diseases 2010 10:105
    Content type: Research article Published on:

  39. Streptococcus pneumoniae is one of the most frequently encountered pathogens in humans but its differentiation from closely related but less pathogenic streptococci remains a challenge.

    Authors: Nabil Abdullah El Aila, Stefan Emler, Tarja Kaijalainen, Thierry De Baere, Bart Saerens, Elife Alkan, Pieter Deschaght, Rita Verhelst and Mario Vaneechoutte
    Citation: BMC Infectious Diseases 2010 10:104
    Content type: Research article Published on:

  40. The administration of hepatitis B immunoglobulin followed by hepatitis B vaccine can result in a protective efficacy of almost 90% in mother-to-child transmission of hepatitis B virus (HBV). However, little is...

    Authors: Haruki Komatsu, Ayano Inui, Tsuyoshi Sogo, Eitaro Hiejima, Akihiko Tateno, Paul Klenerman and Tomoo Fujisawa
    Citation: BMC Infectious Diseases 2010 10:103
    Content type: Research article Published on:

  41. Kocuria, established by Stackebrandt et al., previously was classified into Micrococcus. Only two species, K. rosea and K. kristinae are reported to be associated as pathogenic and found with catheter-related ba...

    Authors: Cheng-Yu Tsai, Shou-hsin Su, Yu-Hsin Cheng, Yu-lin Chou, Tai-Hsin Tsai and Ann-Shung Lieu
    Citation: BMC Infectious Diseases 2010 10:102
    Content type: Case report Published on:

  42. Increasing resistance to quinolones and ceftriaxone in non typhoidal Salmonellae is a global concern. Resistance to quinolone and 3rd generation cephalosporin amongst non typhoidal Salmonellae (NTS) from Pakistan...

    Authors: Kauser Jabeen, Afia Zafar, Seema Irfan, Erum Khan, Vikram Mehraj and Rumina Hasan
    Citation: BMC Infectious Diseases 2010 10:101
    Content type: Research article Published on:

  43. The detection of Brucellae in tissue specimens using PCR assays is difficult because the amount of bacteria is usually low. Therefore, optimised DNA extraction methods are critical. The aim of this study was t...

    Authors: Herbert Tomaso, Mireille Kattar, Meike Eickhoff, Ulrich Wernery, Sascha Al Dahouk, Eberhard Straube, Heinrich Neubauer and Holger C Scholz
    Citation: BMC Infectious Diseases 2010 10:100
    Content type: Research article Published on:

  44. On the 30th September 2009, the pandemic (H1N1) 2009 influenza vaccine was made available to adults and children aged 10 years and over, in Australia. Acceptance of a novel vaccine is influenced by perceptions...

    Authors: Holly Seale, Anita E Heywood, Mary-Louise McLaws, Kirsten F Ward, Chris P Lowbridge, Debbie Van and C Raina MacIntyre
    Citation: BMC Infectious Diseases 2010 10:99
    Content type: Research article Published on:

  45. Sexual transmitted infections (STIs) have increased in Germany and other countries in Europe since the mid-nineties. To obtain a better picture of diagnostic methods used in STI testing institutions in Germany...

    Authors: Andreas Gilsdorf, Alexandra Hofmann, Osamah Hamouda and Viviane Bremer
    Citation: BMC Infectious Diseases 2010 10:98
    Content type: Research article Published on:

  46. Concerns about the hepatitis C virus (HCV) are due to the high risk of chronic liver disease and poor treatment efficacy. Synthesizing evidence from multiple data sources is becoming widely used to estimate HC...

    Authors: Annunziata Faustini, Paola Colais, Emanuele Fabrizi, Anna Maria Bargagli, Marina Davoli, Domenico Di Lallo, Anteo Di Napoli, Patrizio Pezzotti, Chiara Sorge, Rita Grillo, Carla Maresca, Olga Recchia and Carlo A Perucci
    Citation: BMC Infectious Diseases 2010 10:97
    Content type: Research article Published on:

  47. Little is known about the prevalence of pulmonary tuberculosis (TB) in low income countries. We conducted a cross sectional survey for pulmonary TB and TB symptoms in Bissau, Guinea-Bissau, in an urban cohort ...

    Authors: Morten Bjerregaard-Andersen, Zacarias J da Silva, Pernille Ravn, Morten Ruhwald, Paul L Andersen, Morten Sodemann, Per Gustafson, Peter Aaby and Christian Wejse
    Citation: BMC Infectious Diseases 2010 10:96
    Content type: Research article Published on:

  48. Salmonella enterica is an important emerging cause of invasive infections worldwide. However, population-based data are limited. The objective of this study was to define the occurrence of S. enterica bacteremia...

    Authors: Kevin B Laupland, Henrik C Schønheyder, Karina J Kennedy, Outi Lyytikäinen, Louis Valiquette, John Galbraith and Peter Collignon
    Citation: BMC Infectious Diseases 2010 10:95
    Content type: Research article Published on:

  49. Ingestion of cranberry (Vaccinium macrocarpon Ait.) has traditionally been utilized for prevention of urinary tract infections. The proanthocyanidins (PACs) in cranberry, in particular the A-type linkages have be...

    Authors: Amy B Howell, Henry Botto, Christophe Combescure, Anne-Béatrice Blanc-Potard, Lluis Gausa, Tetsuro Matsumoto, Peter Tenke, Albert Sotto and Jean-Philippe Lavigne
    Citation: BMC Infectious Diseases 2010 10:94
    Content type: Research article Published on:

  50. In recent years there has been renewed interest in the use of air ionizers to control the spread of infection in hospitals and a number of researchers have investigated the biocidal action of ions in both air ...

    Authors: Simon J Shepherd, Clive B Beggs, Caroline F Smith, Kevin G Kerr, Catherine J Noakes and P Andrew Sleigh
    Citation: BMC Infectious Diseases 2010 10:92
    Content type: Research article Published on:

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