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  1. A prospective observational registry assessed real world experience with caspofungin monotherapy or combination therapy for the initial or salvage treatment of proven or probable invasive aspergillosis (IA).

    Authors: Johan Maertens, Gerlinde Egerer, Wan Shik Shin, Dietmar Reichert, Michael Stek, Sheenu Chandwani, Malathi Shivaprakash and Claudio Viscoli
    Citation: BMC Infectious Diseases 2010 10:182
  2. Altered blood glucose concentration is commonly observed in patients with sepsis, even among those without hypoglycemic treatments or history of diabetes mellitus. These alterations in blood glucose are potent...

    Authors: Galo Peralta, M Blanca Sánchez, J Carlos Garrido, Begoña Ceballos, Fátima Mateos, Inés De Benito and M Pía Roiz
    Citation: BMC Infectious Diseases 2010 10:181
  3. The diagnosis of typhoid fever is confirmed by culture of Salmonella enterica serotype Typhi (S. typhi). However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing...

    Authors: Benedikt Ley, George Mtove, Kamala Thriemer, Ben Amos, Lorenz von Seidlein, Ilse Hendriksen, Abraham Mwambuli, Aikande Shoo, Rajabu Malahiyo, Shaali M Ame, Deok R Kim, Leon R Ochiai, John D Clemens, Hugh Reyburn, Harald Wilfing, Stephen Magesa…
    Citation: BMC Infectious Diseases 2010 10:180
  4. Although a dramatic decrease in AIDS progression has been observed after Highly Active Anti Retroviral Therapy (HAART) in both low- and high-resource settings, few data support that fact in low-resource settings.

    Authors: Pierre De Beaudrap, Jean-François Etard, Assane Diouf, Ibrahima Ndiaye, Guèye Fatou N Ndèye, Papa S Sow, Kane Coumba T Ndèye, René Ecochard and Eric Delaporte
    Citation: BMC Infectious Diseases 2010 10:179
  5. EV71 is associated with the fatal cases of brain stem encephalitis during large HFMD outbreaks from 1998 to 2008. EV71 may continuously shed from upper respiratory tracts and feces of HFMD patients for relativ...

    Authors: Jun Han, Xue-Jun Ma, Jun-Feng Wan, Ying-Hui Liu, Yan-Ling Han, Cao Chen, Chan Tian, Chen Gao, Miao Wang and Xiao-Ping Dong
    Citation: BMC Infectious Diseases 2010 10:178
  6. Tuberculosis (TB) is one of the major public health problems in Zambia. However, information about lineages of M. tuberculosis complex (MTBC) isolates useful for epidemiology investigations is unknown. In this st...

    Authors: Chanda Mulenga, Isdore C Shamputa, David Mwakazanga, Nathan Kapata, Françoise Portaels and Leen Rigouts
    Citation: BMC Infectious Diseases 2010 10:177
  7. Despite the availability of effective antibiotic therapies, pneumococcal meningitis (PM) has a case fatality rate of up to 30% and causes neurological sequelae in up to half of the surviving patients. The unde...

    Authors: Matthias Wittwer, Denis Grandgirard, Janine Rohrbach and Stephen L Leib
    Citation: BMC Infectious Diseases 2010 10:176
  8. The prevalence of pulmonary tuberculosis among college students in Shaanxi is high. Although tuberculosis leaves much psychological and social impact on patients, little is known about its impact on college st...

    Authors: Shao-Ru Zhang, Hong Yan, Jin-Jing Zhang, Tian-Hua Zhang, Xiao-Hong Li and Yin-Ping Zhang
    Citation: BMC Infectious Diseases 2010 10:174
  9. Previous studies, conducted in the urban of Antananarivo, showed low rate of confirmed malaria cases. We used a geographical and environmental approach to investigate the contribution of environmental factors ...

    Authors: Fanjasoa Rakotomanana, Jocelyn Ratovonjato, Rindra V Randremanana, Laurence Randrianasolo, Rogelin Raherinjafy, Jean-Paul Rudant and Vincent Richard
    Citation: BMC Infectious Diseases 2010 10:173
  10. To ensure sustainable routine surveillance of mosquito vectors, simple, effective and ethically acceptable tools are required. As a part of that, we evaluated the efficiency of resting boxes baited with fresh ...

    Authors: Aneth M Mahande, Beda J Mwang'onde, Shandala Msangi, Epiphania Kimaro, Ladslaus L Mnyone, Humphrey D Mazigo, Michael J Mahande and Eliningaya J Kweka
    Citation: BMC Infectious Diseases 2010 10:172
  11. To examine common antimicrobial regimens used in eradicating certain nosocomial Gram-negative pathogens and determine which ones are likely to be the most suitable as empirical choices in Shenyang, China.

    Authors: Yun Zhuo Chu, Su Fei Tian, Bai Yi Chen, Hua Nian, Hong Shang and Guo Quan Sun
    Citation: BMC Infectious Diseases 2010 10:171
  12. The use of cell culture for the diagnosis of human metapneumovirus (hMPV) infection is uncommon at present and molecular method such as reverse-transcription PCR (RT-PCR) has been widely and most commonly used...

    Authors: Yoko Matsuzaki, Katsumi Mizuta, Emi Takashita, Michiko Okamoto, Tsutomu Itagaki, Fumio Katsushima, Yuriko Katsushima, Yukio Nagai and Hidekazu Nishimura
    Citation: BMC Infectious Diseases 2010 10:170
  13. Previous studies have indicated an increased risk of myocardial infarction (MI) in HIV infected individuals especially after start of highly active antiretroviral therapy (HAART). It is however controversial w...

    Authors: Line D Rasmussen, Lars H Omland, Court Pedersen, Jan Gerstoft, Gitte Kronborg, Janne Jensen and Niels Obel
    Citation: BMC Infectious Diseases 2010 10:169
  14. Influenza vaccination in infants and children with existing health complications is current practice in many countries, but healthy children are also susceptible to influenza, sometimes with complications. The...

    Authors: Vytautas Usonis, Ioana Anca, Francis André, Roman Chlibek, Inga Ivaskeviciene, Atanas Mangarov, Zsófia Mészner, Roman Prymula, Pavol Šimurka, Eda Tamm and Goran Tešović
    Citation: BMC Infectious Diseases 2010 10:168
  15. The role of adaptive immunity in severe influenza is poorly understood. The occurrence of influenza A/H5N1 in a patient with HIV provided a rare opportunity to investigate this.

    Authors: Annette Fox, Peter Horby, Nguyen Hong Ha, Le Nguyen Minh Hoa, Nguyen Tien Lam, Cameron Simmons, Jeremy Farrar, Nguyen Van Kinh and Heiman Wertheim
    Citation: BMC Infectious Diseases 2010 10:167
  16. Mathematical models of infection that consider targeted interventions are exquisitely dependent on the assumed mixing patterns of the population. We report on a pilot study designed to assess three different m...

    Authors: James M McCaw, Kristian Forbes, Paula M Nathan, Philippa E Pattison, Garry L Robins, Terence M Nolan and Jodie McVernon
    Citation: BMC Infectious Diseases 2010 10:166
  17. Pulmonary tuberculosis, the most common clinical form of mycobacterial diseases, is a granulomatous disease of the lungs caused by Mycobaterium tuberculosis. A number of genes have been identified in studies of d...

    Authors: Shilpy Sharma, Jaishriram Rathored, Balaram Ghosh and Surendra K Sharma
    Citation: BMC Infectious Diseases 2010 10:165
  18. Anti-viral prophylaxis is used to prevent the transmission of influenza. We studied serological confirmation of 2009 Influenza A (H1N1) infections during oseltamivir prophylaxis and after cessation of prophyla...

    Authors: Vernon J Lee, Jonathan Yap, Joshua K Tay, Ian Barr, Qiuhan Gao, Hanley J Ho, Boon Huan Tan, Paul M Kelly, Paul A Tambyah, Anne Kelso and Mark I Chen
    Citation: BMC Infectious Diseases 2010 10:164
  19. Resistance of the malaria parasite Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) has evolved worldwide. In the archipelago of São Tomé and Principe (STP), West Africa, although SP resistance is highly p...

    Authors: Patrícia Salgueiro, José L Vicente, Conceição Ferreira, Vânia Teófilo, André Galvão, Virgílio E do Rosário, Pedro Cravo and João Pinto
    Citation: BMC Infectious Diseases 2010 10:163
  20. Several studies have shown a relatively high mortality rate among young people infected by the 2009 pandemic influenza A (H1N1) virus. Here we compared the age distributions of morbidity and mortality during t...

    Authors: Magali Lemaitre and Fabrice Carrat
    Citation: BMC Infectious Diseases 2010 10:162
  21. Tuberculosis is a highly infectious disease that is spread from person to person by infected aerosols emitted by patients with respiratory forms of the disease. We describe a novel device that utilizes immunos...

    Authors: Ruth McNerney, Beyene A Wondafrash, Kebede Amena, Ato Tesfaye, Elaine M McCash and Nicol J Murray
    Citation: BMC Infectious Diseases 2010 10:161
  22. Previous studies regarding the prognosis of patients infected with MRSA isolates characterized by a high minimum inhibitory concentration (MIC) for vancomycin have generally used a commercial Etest. Little res...

    Authors: Jiun-Ling Wang, Jann-Tay Wang, Wang-Huei Sheng, Yee-Chun Chen and Shan-Chwen Chang
    Citation: BMC Infectious Diseases 2010 10:159
  23. Vertebral osteomyelitis is a common manifestation of osteomyelitis in adults and associated with considerable morbidity. Limited data exist regarding hematogenous vertebral osteomyelitis. Our objective was to ...

    Authors: Kavita P Bhavan, Jonas Marschall, Margaret A Olsen, Victoria J Fraser, Neill M Wright and David K Warren
    Citation: BMC Infectious Diseases 2010 10:158
  24. There is conclusive evidence that human papillomavirus (HPV) infections of the cervix are a necessary cause of cervical cancer. In Italy there are consistent data of HPV prevalence in women aged 25 - 64 years,...

    Authors: Massimo Confortini, Francesca Carozzi, Marco Zappa, Leonardo Ventura, Anna Iossa, Paola Cariaggi, Livia Brandigi, Mario Franchini, Francesco Mirri, Paolo Viacava, Aurora Scarfantoni, Daniela Bazzanti and Cristina Sani
    Citation: BMC Infectious Diseases 2010 10:157
  25. Smoking is known to aggravate tuberculosis (TB), but such information has been ignored in clinical practice, as it was not thought to be relevant. The aim of this study is to assess the benefits of smoking ces...

    Authors: Chi-Pang Wen, Ta-Chien Chan, Hui-Ting Chan, Min-Kuang Tsai, Ting-Yuang Cheng and Shan-Pou Tsai
    Citation: BMC Infectious Diseases 2010 10:156
  26. The first imported case of pandemic influenza (H1N1) 2009 in Germany was confirmed in April 2009. However, the first wave with measurable burden of disease started only in October 2009. The basic epidemiologic...

    Authors: Gabriele Poggensee, Andreas Gilsdorf, Silke Buda, Tim Eckmanns, Hermann Claus, Doris Altmann, Gérard Krause and Walter Haas
    Citation: BMC Infectious Diseases 2010 10:155
  27. Interferon gamma is a major macrophage-activating cytokine during infection with Mycobacterium tuberculosis, the causative pathogen of tuberculosis, and its role has been well established in animal models and in ...

    Authors: Marlo Möller, Almut Nebel, Paul D van Helden, Stefan Schreiber and Eileen G Hoal
    Citation: BMC Infectious Diseases 2010 10:154
  28. Oxacillin continues to be an important agent in the treatment of staphylococcal infections; many generic products are available and the only requirement for their approval is demonstration of pharmaceutical eq...

    Authors: Carlos A Rodriguez, Maria Agudelo, Andres F Zuluaga and Omar Vesga
    Citation: BMC Infectious Diseases 2010 10:153
  29. HMG CoA reductase inhibitors (statins) in patients with bacteremic sepsis have shown significant survival benefits in several studies. There is no data on the effect of statins in candidemic patients, however ...

    Authors: Graeme N Forrest, Angela M Kopack and Eli N Perencevich
    Citation: BMC Infectious Diseases 2010 10:152
  30. Candida represents the most common cause of invasive fungal disease, and candidal blood stream infections (CBSI) are prevalent in the ICU. Inappropriate antifungal therapy (IAT) is known to increase a patient'...

    Authors: Marya D Zilberberg, Marin H Kollef, Heather Arnold, Andrew Labelle, Scott T Micek, Smita Kothari and Andrew F Shorr
    Citation: BMC Infectious Diseases 2010 10:150
  31. To control multidrug resistant tuberculosis (MDR-TB), the drug susceptibility profile is needed to guide therapy. Classical drug susceptibility testing (DST) may take up to 2 to 4 months. The GenoType® MTBDRplus ...

    Authors: Mai NT Huyen, Edine W Tiemersma, Nguyen TN Lan, Frank GJ Cobelens, Nguyen H Dung, Dinh N Sy, Tran N Buu, Kristin Kremer, Pham T Hang, Maxine Caws, Richard O'Brien and Dick van Soolingen
    Citation: BMC Infectious Diseases 2010 10:149
  32. Antibiotics are not only small molecules with therapeutic activity in killing or inhibiting microbial growth, but can also act as signaling molecules affecting gene expression in bacterial communities. A few s...

    Authors: Fedora Babić, Vittorio Venturi and Gordana Maravić-Vlahoviček
    Citation: BMC Infectious Diseases 2010 10:148
  33. Human cytomegalovirus (CMV) infection still causes significant morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Therefore, it is extremely important to diagnosis and mon...

    Authors: Renata MB Peres, Cláudia RC Costa, Paula D Andrade, Sandra HA Bonon, Dulcinéia M Albuquerque, Cristiane de Oliveira, Afonso C Vigorito, Francisco JP Aranha, Cármino A de Souza and Sandra CB Costa
    Citation: BMC Infectious Diseases 2010 10:147
  34. Because of better comfort, air conditioning systems are a common feature in automobiles these days. However, its impact on the number of particles and microorganisms inside the vehicle - and by this its impact...

    Authors: Ralf-Peter Vonberg, Petra Gastmeier, Björn Kenneweg, Hinrich Holdack-Janssen, Dorit Sohr and Iris F Chaberny
    Citation: BMC Infectious Diseases 2010 10:146
  35. During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. We describe the clinical characteristics and factors associated with the death of patients who were hospitalized with...

    Authors: Wei Cui, Hongwen Zhao, Xu Lu, Ying Wen, Ying Zhou, Baocheng Deng, Yu Wang, Wen Wang, Jian Kang and Pei Liu
    Citation: BMC Infectious Diseases 2010 10:145
  36. Salmonella Typhi (S. Typhi) causes typhoid fever, which remains an important public health issue in many developing countries. Kathmandu, the capital of Nepal, is an area of high incidence and the pediatric popu...

    Authors: Kathryn E Holt, Stephen Baker, Sabina Dongol, Buddha Basnyat, Neelam Adhikari, Stephen Thorson, Anoop S Pulickal, Yajun Song, Julian Parkhill, Jeremy J Farrar, David R Murdoch, Dominic F Kelly, Andrew J Pollard and Gordon Dougan
    Citation: BMC Infectious Diseases 2010 10:144
  37. Febrile neutropenia carries a high risk of sepsis complications, and the identification of biomarkers capable to identify high risk patients is a great challenge. Angiopoietins (Ang -) are cytokines involved i...

    Authors: Brunna E Alves, Silmara AL Montalvao, Franciso JP Aranha, Tania FG Siegl, Carmino A Souza, Irene Lorand-Metze, Joyce M Annichino-Bizzacchi and Erich V De Paula
    Citation: BMC Infectious Diseases 2010 10:143
  38. Dengue is a major public health problem in tropical and subtropical countries. Rapid and easy diagnosis of dengue can assist patient triage and care-management. The detection of DENV NS1 on rapid lateral flow ...

    Authors: Vianney Tricou, Hang TT Vu, Nhu VN Quynh, Chau VV Nguyen, Hien T Tran, Jeremy Farrar, Bridget Wills and Cameron P Simmons
    Citation: BMC Infectious Diseases 2010 10:142
  39. The detailed analysis of an outbreak database has been undertaken to examine the role of contact tracing in controlling an outbreak of possible avian influenza in humans. The outbreak, initiating from the purc...

    Authors: Ken TD Eames, Cerian Webb, Kathrin Thomas, Josie Smith, Roland Salmon and J Mark F Temple
    Citation: BMC Infectious Diseases 2010 10:141
  40. In tuberculosis (TB) endemic parts of the world, patients with pulmonary symptoms are managed as "smear-negative TB patients" if they do not improve on a two-week presumptive, broad-spectrum course of antibiot...

    Authors: Lotte Jensen, Andreas V Jensen, George Praygod, Jeremiah Kidola, Daniel Faurholt-Jepsen, John Changalucha, Nyagosya Range, Henrik Friis, Jannik Helweg-Larsen, Jorgen S Jensen and Aase B Andersen
    Citation: BMC Infectious Diseases 2010 10:140
  41. During the SARS pandemic in Hong Kong, panic and worry were prevalent in the community and the general public avoided staying in public areas. Such avoidance behaviors could greatly impact daily routines of th...

    Authors: Joseph TF Lau, Sian Griffiths, Kai Chow Choi and Hi Yi Tsui
    Citation: BMC Infectious Diseases 2010 10:139
  42. Recent interest has focused on the potential use of serial interferon gamma (IFN-γ) release assay (IGRA) measurements to assess the response to anti-tuberculous (TB) treatment. The kinetics of IFN-γ responses to

    Authors: Tom G Connell, Mary-Ann Davies, Christine Johannisen, Kathryn Wood, Sandy Pienaar, Katalin A Wilkinson, Robert J Wilkinson, Heather J Zar, David Beatty, Mark P Nicol, Nigel Curtis and Brian Eley
    Citation: BMC Infectious Diseases 2010 10:138
  43. The objective of this study was to estimate the effect of male circumcision (MC) on HIV acquisition estimated using HIV incidence assays and to compare it to the effect measured by survival analysis.

    Authors: Agnès Fiamma, Pascale Lissouba, Oliver E Amy, Beverley Singh, Oliver Laeyendecker, Thomas C Quinn, Dirk Taljaard and Bertran Auvert
    Citation: BMC Infectious Diseases 2010 10:137
  44. In infectious disease surveillance, when the laboratory confirmation of the cases is time-consuming, there is often a time lag between the number of suspect cases and the number of confirmed cases. This study ...

    Authors: Pei-Hung Chuang, Jen-Hsiang Chuang and I-Feng Lin
    Citation: BMC Infectious Diseases 2010 10:136
  45. Bloodstream Infections (BSIs) in neutropenic patients often cause considerable morbidity and mortality. Therefore, the surveillance and early identification of patients at high risk for developing BSIs might b...

    Authors: Eleni Apostolopoulou, Vasilios Raftopoulos, Konstantinos Terzis and Ioannis Elefsiniotis
    Citation: BMC Infectious Diseases 2010 10:135
  46. Although seasonal influenza vaccine is effective in the elderly, immune responses to vaccination are lower in the elderly than in younger adults. Strategies to optimise responses to vaccination in the elderly ...

    Authors: Pierre Van Damme, Robert Arnou, Froukje Kafeja, Anne Fiquet, Patrick Richard, Stéphane Thomas, Gilles Meghlaoui, Sandrine Isabelle Samson and Emilio Ledesma
    Citation: BMC Infectious Diseases 2010 10:134
  47. Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA), is an important cause of pyogenic skin and soft tissue infections (SSTIs). The aim of present study is to investigate the molecular cha...

    Authors: Dan Yao, Fang-you Yu, Zhi-qiang Qin, Chun Chen, Su-su He, Zeng-qiang Chen, Xue-qing Zhang and Liang-xing Wang
    Citation: BMC Infectious Diseases 2010 10:133

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