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  1. An estimated 10% of tuberculosis (TB) deaths are attributable to problematic alcohol use globally, however the causal pathways through which problem alcohol use has an impact on TB treatment outcome is not cle...

    Authors: Bronwyn Myers, Tara C Bouton, Elizabeth J Ragan, Laura F White, Helen McIlleron, Danie Theron, Charles D H Parry, C Robert Horsburgh, Robin M Warren and Karen R Jacobson
    Citation: BMC Infectious Diseases 2018 18:488
    Content type: Study protocol Published on:

  2. The World Health Organization recommends all men who have sex with men (MSM) receive Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) testing. MSM in China are a high-risk group for HBV and HCV infection, b...

    Authors: Thomas Fitzpatrick, Kali Zhou, Yu Cheng, Po-Lin Chan, Fuqiang Cui, Weiming Tang, Katie R Mollan, Wilson Guo and Joseph D Tucker
    Citation: BMC Infectious Diseases 2018 18:489
    Content type: Study protocol Published on:

  3. Staphylococcus aureus bacteraemia is a common and significant infection, associated with high rates of mortality. Therefore, early identification is important for the initiation of appropriate treatment. The obje...

    Authors: Yoshiro Hadano, Miwako Isoda, Kazushige Ishibashi and Tatsuyuki Kakuma
    Citation: BMC Infectious Diseases 2018 18:490
    Content type: Research article Published on:

  4. Carbapenem resistance in Acinetobacter baumannii in China was mainly mediated by OXA-23-like carbapenemases, while OXA-24/40-like carbapenemases were rarely identified. OXA-72 is one variant of OXA-24/40-like car...

    Authors: Yong Chen, Yuying Yang, Lin Liu, Guangbin Qiu, Xuelin Han, Shuguang Tian, Jingya Zhao, Fangyan Chen, Hajo Grundmann, Haifeng Li, Jinke Sun and Li Han
    Citation: BMC Infectious Diseases 2018 18:491
    Content type: Research article Published on:

  6. The depletion of CD4 cell is the underlying reason for TB hyper-susceptibility among people with HIV. Consequently, the trend of TB dynamics is usually hidden by the HIV outbreak.

    Authors: Dao Nguyen Vinh, Dang Thi Minh Ha, Nguyen Thi Hanh, Guy Thwaites, Maciej F. Boni, Hannah E. Clapham and Nguyen Thuy Thuong Thuong
    Citation: BMC Infectious Diseases 2018 18:494
    Content type: Research article Published on:

  7. Leishmaniasis is endemic in many countries worldwide, with a prevalence of 12 million people infected, and an estimated annual incidence of 500 000 visceral leishmaniasis cases. In Europe visceral leishmaniasi...

    Authors: Charlotte Adamczick, Alexa Dierig, Tatjana Welzel, Alexandra Schifferli, Johannes Blum and Nicole Ritz
    Citation: BMC Infectious Diseases 2018 18:495
    Content type: Case report Published on:

  8. Herpes zoster (HZ) is a painful dermatomal rash caused by reactivation of latent varicella zoster virus surviving in the patient’s sensory ganglia after a previous episode of varicella. The incidence of HZ inc...

    Authors: Desmond Curran, Ruprecht Schmidt-Ott, Ulf Schutter, Jörg Simon, Anastassia Anastassopoulou and Sean Matthews
    Citation: BMC Infectious Diseases 2018 18:496
    Content type: Research article Published on:

  9. Rotavirus is a leading cause of severe diarrheal disease, and one of the common causes of death in children aged under five years old. The dominant epidemic strains may change in different years in the same ar...

    Authors: Yi Tian, Abrar Ahmad Chughtai, Zhiyong Gao, Hanqiu Yan, Yanwei Chen, Baiwei Liu, Da Huo, Lei Jia, Quanyi Wang and Chandini Raina MacIntyre
    Citation: BMC Infectious Diseases 2018 18:497
    Content type: Research article Published on:

  10. Ebolavirus and Marburgvirus are genera of the virus family Filoviridae. Filoviruses cause rare but fatal viral hemorrhagic fevers (VHFs) in remote villages of equatorial Africa with potential for regional and int...

    Authors: Peace Babirye, Carol Musubika, Samuel Kirimunda, Robert Downing, Julian J Lutwama, Edward K Mbidde, Jacqueline Weyer, Janusz T Paweska, Moses L Joloba and Misaki Wayengera
    Citation: BMC Infectious Diseases 2018 18:498
    Content type: Research article Published on:

  11. Youth in southern Africa, particularly adolescent girls and young women, are a key population for HIV prevention interventions. Untreated genital tract infections (GTIs) increase both HIV transmission and acqu...

    Authors: Angela Kaida, Janan J. Dietrich, Fatima Laher, Mags Beksinska, Manjeetha Jaggernath, Megan Bardsley, Patricia Smith, Laura Cotton, Pooja Chitneni, Kalysha Closson, David A. Lewis, Jenni A. Smit, Thumbi Ndung’u, Mark Brockman and Glenda Gray
    Citation: BMC Infectious Diseases 2018 18:499
    Content type: Research article Published on:

  12. Visceral leishmaniasis (VL), caused by Leishmania donovani complex parasites, is a neglected parasitic disease that is generally fatal if untreated. Despite decades of research to develop a sensitive VL diagnosti...

    Authors: Wen-Wei Zhang, Ayan Kumar Ghosh, Raodoh Mohamath, Jacqueline Whittle, Alessandro Picone, Patrick Lypaczewski, Momar Ndao, Randall F Howard, Pradeep Das, Steven G Reed and Greg Matlashewski
    Citation: BMC Infectious Diseases 2018 18:500
    Content type: Research article Published on:

  13. Identification of factors associated with antifungal utilization in neonatal, pediatric, and adult patient groups is needed to guide antifungal stewardship initiatives in academic medical centers.

    Authors: Jeremy S. Stultz, Rose Kohinke and Amy L. Pakyz
    Citation: BMC Infectious Diseases 2018 18:501
    Content type: Research article Published on:

  14. Vaccine regulation in China meets World Health Organization standards, but China’s vaccine industry and immunization program have some characteristics that differ from other countries. We described the history...

    Authors: Yaming Zheng, Lance Rodewald, Juan Yang, Ying Qin, Mingfan Pang, Luzhao Feng and Hongjie Yu
    Citation: BMC Infectious Diseases 2018 18:502
    Content type: Research article Published on:

  15. HIV pre-exposure prophylaxis (PrEP) is highly effective for prevention of HIV acquisition, but requires HIV testing at regular intervals. Female sex workers (FSWs) are a priority population for HIV prevention ...

    Authors: Katrina F. Ortblad, Michael M. Chanda, Daniel Kibuuka Musoke, Thomson Ngabirano, Magdalene Mwale, Aidah Nakitende, Steven Chongo, Nyambe Kamungoma, Catherine Kanchele, Till Bärnighausen and Catherine E. Oldenburg
    Citation: BMC Infectious Diseases 2018 18:503
    Content type: Research article Published on:

  16. Healthcare exposure may increase drug-resistant Enterobacteriaceae colonization risk. Nascent antimicrobial stewardship efforts in low- and middle-income countries require setting-specific data. We aimed to ev...

    Authors: Renu Bharadwaj, Matthew L Robinson, Usha Balasubramanian, Vandana Kulkarni, Anju Kagal, Priyanka Raichur, Sandhya Khadse, Dileep Kadam, Chhaya Valvi, Aarti Kinikar, Savita Kanade, Nishi Suryavanshi, Ivan Marbaniang, George Nelson, Julia Johnson, Jonathan Zenilman…
    Citation: BMC Infectious Diseases 2018 18:504
    Content type: Research article Published on:

  17. Antimicrobial resistance is a public-health threat and antimicrobial consumption is the main contributor. The ten-valent pneumococcal conjugate vaccine (PHiD-CV10) was introduced into the Icelandic vaccination...

    Authors: Elias Eythorsson, Samuel Sigurdsson, Birgir Hrafnkelsson, Helga Erlendsdóttir, Ásgeir Haraldsson and Karl G Kristinsson
    Citation: BMC Infectious Diseases 2018 18:505
    Content type: Research article Published on:

  18. The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-expo...

    Authors: Liesbeth F Mieras, Anna T Taal, Wim H van Brakel, Emmanuelle Cambau, Paul R Saunderson, W Cairns S Smith, Cita Rosita S Prakoeswa, Linda Astari, David M Scollard, Dejair Caitano do Nascimento, Jacques Grosset, Hemanta K Kar, Shinzo Izumi, Laura Gillini, Marcos C L Virmond and Marieke G G Sturkenboom
    Citation: BMC Infectious Diseases 2018 18:506
    Content type: Debate Published on:

  19. Healthcare-associated infections caused by Pseudomonas aeruginosa are associated with poor outcomes. However, the role of P. aeruginosa in surgical site infections after colorectal surgery has not been evaluated....

    Authors: A Gomila, J Carratalà, J M Badia, D Camprubí, M Piriz, E Shaw, V Diaz-Brito, E Espejo, C Nicolás, M Brugués, R Perez, A Lérida, A Castro, S Biondo, D Fraccalvieri, E Limón…
    Citation: BMC Infectious Diseases 2018 18:507
    Content type: Research article Published on:

  20. Antistaphylococcal penicillins (ASPs) and cefazolin have become the most frequent choices for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) infections. However, the best therapeutic agent ...

    Authors: Changcheng Shi, Yubo Xiao, Qi Zhang, Qingyu Li, Fei Wang, Jing Wu and Nengming Lin
    Citation: BMC Infectious Diseases 2018 18:508
    Content type: Research article Published on:

  21. Human papillomavirus (HPV), Epstein-Barr virus (EBV) and herpes simplex virus (HSV) cause sexually transmitted diseases (STDs) that are frequently found in men who have sex with men (MSM) with human immunodeficie...

    Authors: Jureeporn Chuerduangphui, Kanisara Proyrungroj, Chamsai Pientong, Saowarop Hinkan, Jiratha Budkaew, Charinya Pimson, Bandit Chumworathayi, Ploenpit Hanond and Tipaya Ekalaksananan
    Citation: BMC Infectious Diseases 2018 18:509
    Content type: Research article Published on:

  22. Respiratory tract infections (RTIs) are the most common illness in children, and rapid diagnosis is required for the optimal management of RTIs, especially severe infections.

    Authors: Jin Li, Yue Tao, Mingyu Tang, Bailu Du, Yijun Xia, Xi Mo and Qing Cao
    Citation: BMC Infectious Diseases 2018 18:510
    Content type: Research article Published on:

  23. Clinical studies and mathematical simulation suggest that active surveillance with contact isolation is associated with reduced vancomycin-resistant enterococci (VRE) prevalence compared to passive surveillanc...

    Authors: Agnes Loo Yee Cheah, Allen C. Cheng, Denis Spelman, Roger L. Nation, David C. M. Kong and Emma S. McBryde
    Citation: BMC Infectious Diseases 2018 18:511
    Content type: Research article Published on:

  25. We aimed to identify the main spreading clones, describe the resistance mechanisms associated with carbapenem- and/or multidrug-resistant P. aeruginosa and characterize patients at risk of acquiring these strains...

    Authors: Kaidi Telling, Mailis Laht, Age Brauer, Maido Remm, Veljo Kisand, Matti Maimets, Tanel Tenson and Irja Lutsar
    Citation: BMC Infectious Diseases 2018 18:513
    Content type: Research article Published on:

  26. Incomplete virologic suppression results in mutations associated with resistance and is a major obstacle to disease control. We analyzed the genotypic profiles of HIV-1 patients at the time of the first virolo...

    Authors: Marta Iglis Oliveira, Valter Romão de Souza Junior, Claudia Fernanda de Lacerda Vidal and Paulo Sérgio Ramos de Araújo
    Citation: BMC Infectious Diseases 2018 18:514
    Content type: Research article Published on:

  27. Early diagnosis of tuberculosis (TB) and involvement of the public-private partnership are critical to eradicate TB. Patients need to receive proper treatment through the National Tuberculosis Control Programm...

    Authors: K. A. T. M. Ehsanul Huq, Michiko Moriyama, Khalequ Zaman, Mohammod Jobayer Chisti, Julie Long, Akramul Islam, Shahed Hossain, Habiba Shirin, Mohammad Jyoti Raihan, Sajeda Chowdhury and Md Moshiur Rahman
    Citation: BMC Infectious Diseases 2018 18:515
    Content type: Research article Published on:

  28. Viral hepatitis is an important public health issue in sub-Saharan Africa. Due to rising mortality from cirrhosis and hepatocellular carcinoma and limited implementation of screening and treatment programmes, ...

    Authors: Alexander J Stockdale, Collins Mitambo, Dean Everett, Anna Maria Geretti and Melita A Gordon
    Citation: BMC Infectious Diseases 2018 18:516
    Content type: Research article Published on:

  29. The first step of designing any genome-based molecular diagnostic test is to find a specific target sequence. The modified genome comparison method is one of the easiest and most comprehensive ways to achieve ...

    Authors: Alireza Neshani, Reza Kamali Kakhki, Mojtaba Sankian, Hosna Zare, Amin Hooshyar Chichaklu, Mahsa Sayyadi and Kiarash Ghazvini
    Citation: BMC Infectious Diseases 2018 18:517
    Content type: Research article Published on:

  30. Possible cardiotoxicity of sofosbuvir in humans has not been demonstrated yet. Also, since HCV can exert deleterious effects on hearth function, it is of interest to know whether HCV eradication provides any b...

    Authors: Maria Mazzitelli, Carlo Torti, Jolanda Sabatino, Greta Luana D’Ascoli, Chiara Costa, Vincenzo Pisani, Elena Raffetti, Salvatore De Rosa, Alessio Strazzulla, Alfredo Focà, Maria Carla Liberto and Ciro Indolfi
    Citation: BMC Infectious Diseases 2018 18:518
    Content type: Research article Published on:

  31. Prenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide post-exposure prophylaxis. We examined the association between...

    Authors: Vera Ehrenstein, Nickolaj Risbo Kristensen, Brigitta Ursula Monz, Barry Clinch, Andy Kenwright and Henrik Toft Sørensen
    Citation: BMC Infectious Diseases 2018 18:519
    Content type: Research article Published on:

  32. Cryptococcal meningitis remains the leading cause of adult meningitis in Sub-Saharan Africa. Immune Reconstitution Inflammatory Syndrome (IRIS) following anti-retroviral therapy (ART) initiation is an importan...

    Authors: Jayne P. Ellis, Newton Kalata, Elizabeth C. Joekes, Samuel Kampondeni, Laura A. Benjamin, Thomas S. Harrison, David G. Lalloo and Robert S. Heyderman
    Citation: BMC Infectious Diseases 2018 18:520
    Content type: Case report Published on:

  33. Human norovirus is the leading cause of viral gastroenteritis globally, and the GII.4 has been the most predominant genotype for decades. This genotype has numerous variants that have caused repeated epidemics...

    Authors: Nicholas Petronella, Jennifer Ronholm, Menka Suresh, Jennifer Harlow, Oksana Mykytczuk, Nathalie Corneau, Sabah Bidawid and Neda Nasheri
    Citation: BMC Infectious Diseases 2018 18:521
    Content type: Research article Published on:

  34. Aerococcus urinae is a gram-positive, alpha-hemolytic coccus bacterium primarily implicated in less than 1 % of all symptomatic urinary tract infections. Risk factors for disease include male gender, advanced age...

    Authors: Joseph M. Yabes, Serafim Perdikis, David B. Graham and Ana Markelz
    Citation: BMC Infectious Diseases 2018 18:522
    Content type: Case report Published on:

  35. Gemella bergeri is one of the nine species of the genus Gemella and is relatively difficult to identify. We herein describe the first case of septic shock due to a Gemella bergeri coinfection with Eikenella corro...

    Authors: Toshinobu Yamagishi, Mayu Hikone, Kazuhiro Sugiyama, Takahiro Tanabe, Yasuhiro Wada, Michiko Furugaito, Yuko Arai, Yutaka Uzawa, Ryo Mizushima, Keisuke Kamada, Yasutomo Itakura, Shigekazu Iguchi, Atsushi Yoshida, Ken Kikuchi and Yuichi Hamabe
    Citation: BMC Infectious Diseases 2018 18:523
    Content type: Case report Published on:

  36. The prevalence of extended-spectrum β-lactamases (ESBLs) have been reported in clinical isolates obtained from various hospitals in Ethiopia. However, there is no data on the prevalence and antibiotic suscepti...

    Authors: Ahmed Zeynudin, Michael Pritsch, Sören Schubert, Maxim Messerer, Gabriele Liegl, Michael Hoelscher, Tefara Belachew and Andreas Wieser
    Citation: BMC Infectious Diseases 2018 18:524
    Content type: Research article Published on:

  37. The effects of maternal influenza infection on the fetus remain unclear. We studied mild influenza and influenza antibodies in relation to birth weight and risks of pre-eclampsia, preterm birth (PTB), and smal...

    Authors: Ida Laake, Gro Tunheim, Anna Hayman Robertson, Olav Hungnes, Kristian Waalen, Siri E. Håberg, Siri Mjaaland and Lill Trogstad
    Citation: BMC Infectious Diseases 2018 18:525
    Content type: Research article Published on:

  38. Rabies is a significant public health problem in China. Previous spatial epidemiological studies have helped understand the epidemiology of animal and human rabies in China. However, quantification of effects ...

    Authors: Danhuai Guo, Wenwu Yin, Hongjie Yu, Jean-Claude Thill, Weishi Yang, Feng Chen and Deqiang Wang
    Citation: BMC Infectious Diseases 2018 18:526
    Content type: Research article Published on:

  39. Vietnam is endemic for taeniasis and T. solium cysticercosis. Despite this, information on the epidemiological characteristics of the diseases in the Central Highlands of Vietnam are poorly described. The aims of...

    Authors: Dinh Ng-Nguyen, Mark Anthony Stevenson, Kathleen Breen, Trong Van Phan, Van-Anh Thi Nguyen, Tinh Van Vo and Rebecca Justine Traub
    Citation: BMC Infectious Diseases 2018 18:527
    Content type: Research article Published on:

  40. Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel bunyavirus named SFTS virus (SFTSV), which is classified into the genus Phlebovirus and family Phenuiviridae....

    Authors: Jinjing Zhang, Xiaojing Yan, Yan Li, Ran Gao, Pingping Wang and Wenbin Mo
    Citation: BMC Infectious Diseases 2018 18:528
    Content type: Case report Published on:

  41. Adenoviruses (AdV) are non-enveloped, double-stranded DNA viruses with multiple serotypes, which cause a variety of end-organ disease in both immunocompetent and immunocompromised individuals. Some adenoviruse...

    Authors: Rhiannon Ions, Manjith Narayanan, Michael Browning, Erol A. Gaillard, Gary Stiefel and Julian W. Tang
    Citation: BMC Infectious Diseases 2018 18:529
    Content type: Case report Published on:

  42. The outcome of lung nodule(s) with histopathological findings suggestive of tuberculosis (TB) but lack of microbiologic confirmation remains unclear. Whether these patients require anti-TB treatment remains un...

    Authors: Che-Liang Chung, Yen-Fu Chen, Yen-Ting Lin, Jann-Yuan Wang, Shuenn-Wen Kuo and Jin-Shing Chen
    Citation: BMC Infectious Diseases 2018 18:530
    Content type: Research article Published on:

  43. Among men who have sex with men (MSM) in the UK, an estimated 28% have never tested for HIV and only 27% of those at higher risk test at least every 6 months. HIV self-testing (HIVST), where the person takes t...

    Authors: Michelle M. Gabriel, David T. Dunn, Andrew Speakman, Leanne McCabe, Denise Ward, T. Charles Witzel, Justin Harbottle, Simon Collins, Mitzy Gafos, Fiona M. Burns, Fiona C. Lampe, Peter Weatherburn, Andrew Phillips, Sheena McCormack and Alison J. Rodger
    Citation: BMC Infectious Diseases 2018 18:531
    Content type: Study protocol Published on:

  44. Injection drug use (IDU) is a growing public health threat in Virginia, though there is limited knowledge of related morbidity. The purpose of this study was to describe the temporal, geographic and clinical t...

    Authors: Megan E. Gray, Elizabeth T. Rogawski McQuade, W. Michael Scheld and Rebecca A. Dillingham
    Citation: BMC Infectious Diseases 2018 18:532
    Content type: Research article Published on:

  45. Lifelong antiretroviral therapy for HIV infected pregnant and lactating women (Option B+) has been rapidly scaled up but there are concerns about poor retention of women initiating treatment. However, facility...

    Authors: George Kiwanuka, Noah Kiwanuka, Fiston Muneza, Juliet Nabirye, Frederick Oporia, Magdalene A. Odikro, Barbara Castelnuovo and Rhoda K. Wanyenze
    Citation: BMC Infectious Diseases 2018 18:533
    Content type: Research article Published on:

  46. A population-based study of Chlamydia trachomatis (CT) infections is essential in designing a specific control program; however, no large investigation of CT infections among the general population in mainland Ch...

    Authors: Pengcheng Huai, Furong Li, Zhen Li, Lele Sun, Xi’an Fu, Qing Pan, Gongqi Yu, Zemin Chai, Tongsheng Chu, Zihao Mi, Fangfang Bao, Honglei Wang, Bingni Zhou, Chuan Wang, Yonghu Sun, Guiye Niu…
    Citation: BMC Infectious Diseases 2018 18:534
    Content type: Research article Published on:

  47. Community acquired bloodstream infection (CABSI) in low- and middle income countries is associated with a high mortality. This study describes the clinical manifestations, laboratory findings and correlation o...

    Authors: Vu Quoc Dat, Nguyen Thanh Long, Vu Ngoc Hieu, Nguyen Dinh Hong Phuc, Nguyen Van Kinh, Nguyen Vu Trung, H. Rogier van Doorn, Ana Bonell and Behzad Nadjm
    Citation: BMC Infectious Diseases 2018 18:535
    Content type: Research article Published on:

  48. Patients with HIV-associated tuberculosis (TB) often have their TB and HIV managed in separate vertical programs that offer care for each disease with little coordination. Such “siloed” approaches are associat...

    Authors: Michael E Herce, Jill Morse, Dora Luhanga, Jennifer Harris, Helene J Smith, Stable Besa, Graham Samungole, Nzali Kancheya, Monde Muyoyeta and Stewart E Reid
    Citation: BMC Infectious Diseases 2018 18:536
    Content type: Research article Published on:

  49. In the Republic of Congo, artemisinin-based combinations have been recommended for the treatment of uncomplicated malaria since 2006. However, the emergence of resistant parasites again these combinations in S...

    Authors: Pembe Issamou Mayengue, Roch Fabien Niama, Dezi Kouhounina Batsimba, Alida Malonga-Massanga, Igor Louzolo, Nadia Claricelle Loukabou Bongolo, Lucette Macosso, Reyna Ibara Ottia, Ghyslain Kimbassa Ngoma, Louis Régis Dossou-Yovo, Brice Pembet Singana, Gabriel Ahombo, Géril Sekangue Obili, Simon Charles Kobawila and Henri Joseph Parra
    Citation: BMC Infectious Diseases 2018 18:538
    Content type: Research article Published on:

  50. Fomite mediated transmission can be an important pathway causing significant disease transmission in number of settings such as schools, daycare centers, and long-term care facilities. The importance of these ...

    Authors: Alicia N.M. Kraay, Michael A.L. Hayashi, Nancy Hernandez-Ceron, Ian H. Spicknall, Marisa C. Eisenberg, Rafael Meza and Joseph N.S. Eisenberg
    Citation: BMC Infectious Diseases 2018 18:540
    Content type: Research article Published on:

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