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  1. The 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak infected 8,422 individuals leading to 916 deaths around the world. However, there have been few epidemiological studies of SARS comparing epidemi...

    Authors: Eric HY Lau, C Agnes Hsiung, Benjamin J Cowling, Chang-Hsun Chen, Lai-Ming Ho, Thomas Tsang, Chiu-Wen Chang, Christl A Donnelly and Gabriel M Leung

    Citation: BMC Infectious Diseases 2010 10:50

    Content type: Research article

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  2. The role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. The aim of this work was to determine the aetiology, apparent prevalence, spatial distribut...

    Authors: Pilar M Muñoz, Mariana Boadella, Maricruz Arnal, María J de Miguel, Miguel Revilla, David Martínez, Joaquín Vicente, Pelayo Acevedo, Álvaro Oleaga, Francisco Ruiz-Fons, Clara M Marín, José M Prieto, José de la Fuente, Marta Barral, Montserrat Barberán, Daniel Fernández de Luco…

    Citation: BMC Infectious Diseases 2010 10:46

    Content type: Research article

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  3. Typhoid (enteric) fever is still a common disease in many developing countries but current diagnostic tests are inadequate. Studies on pathogenesis and genomics have provided new insight into the organisms tha...

    Authors: Stephen Baker, Michael Favorov and Gordon Dougan

    Citation: BMC Infectious Diseases 2010 10:45

    Content type: Commentary

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  4. Invasive pulmonary aspergillosis (IPA) is a major cause of morbidity and mortality in patients with hematological malignancies in the setting of profound neutropenia and/or hematopoietic stem cell transplantat...

    Authors: Li-Yang Hsu, Ying Ding, Jason Phua, Liang-Piu Koh, Douglas S Chan, Kay-Leong Khoo and Paul A Tambyah

    Citation: BMC Infectious Diseases 2010 10:44

    Content type: Research article

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  5. The aim of this study was to investigate the molecular characteristics of isoniazid resistant Mycobacterium tuberculosis (MTB), as well as its contribution to the dissemination of multi-drug resistant TB (MDR-TB)...

    Authors: Yi Hu, Sven Hoffner, Weili Jiang, Weibing Wang and Biao Xu

    Citation: BMC Infectious Diseases 2010 10:43

    Content type: Research article

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  6. During an infectious disease outbreak, it is critical to learn as much as possible about the concerns, knowledge, attitudes, and behavior of the public. Such information can be crucial to the improvement of co...

    Authors: Hanan H Balkhy, Mostafa A Abolfotouh, Rawabi H Al-Hathlool and Mohammad A Al-Jumah

    Citation: BMC Infectious Diseases 2010 10:42

    Content type: Research article

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  7. About 500 new smear-positive Multidrug-resistant tuberculosis (MDR-TB) cases are estimated to occur per year in Uganda. In 2008 in Kampala, MDR-TB prevalence was reported as 1.0% and 12.3% in new and previousl...

    Authors: Heidi Albert, Freddie Bwanga, Sheena Mukkada, Barnabas Nyesiga, Julius Patrick Ademun, George Lukyamuzi, Melles Haile, Sven Hoffner, Moses Joloba and Richard O'Brien

    Citation: BMC Infectious Diseases 2010 10:41

    Content type: Research article

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  8. Viral load (VL) monitoring is an essential component of the care of HIV positive individuals. Rates of VL monitoring have been shown to vary by HIV risk factor and clinical characteristics. The objective of th...

    Authors: Janet M Raboud, Mona R Loutfy, DeSheng Su, Ahmed M Bayoumi, Marina B Klein, Curtis Cooper, Nima Machouf, Sean Rourke, Sharon Walmsley, Anita Rachlis, P Richard Harrigan, Marek Smieja, Christos Tsoukas, Julio SG Montaner and Robert S Hogg

    Citation: BMC Infectious Diseases 2010 10:40

    Content type: Research article

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  9. Disease severity in Mycoplasma pneumoniae (MP) infection could potentially be related to bacterial factors such as MP genotype (MP1 or MP2; distinguished by different adhesions proteins) or bacterial load in airw...

    Authors: Anna C Nilsson, Per Björkman, Christina Welinder-Olsson, Anders Widell and Kenneth Persson

    Citation: BMC Infectious Diseases 2010 10:39

    Content type: Research article

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  10. Since its first occurrence in the New York City area during 1999, West Nile virus (WNV) has spread rapidly across North America and has become a major public health concern in North America. By 2002, WNV was r...

    Authors: Guiming Wang, Richard B Minnis, Jerrold L Belant and Charles L Wax

    Citation: BMC Infectious Diseases 2010 10:38

    Content type: Research article

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  11. To investigate how the risk of active tuberculosis disease is influenced by time since original infection and to determine whether the risk of reactivation of tuberculosis increases or decreases with age.

    Authors: Harald G Wiker, Tehmina Mustafa, Gunnar A Bjune and Morten Harboe

    Citation: BMC Infectious Diseases 2010 10:37

    Content type: Research article

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  12. The quasispecies nature of HCV may have important implications for viral persistence, pathogenicity and resistance to antiviral agents. The variability of one of the viral proteins, NS5A, is believed to be rel...

    Authors: Cíntia Bittar, Ana Carolina G Jardim, Lilian HT Yamasaki, Artur TL de Queiróz, Claudia MA Carareto, João Renato R Pinho, Isabel Maria VG de Carvalho-Mello and Paula Rahal

    Citation: BMC Infectious Diseases 2010 10:36

    Content type: Research article

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  13. This survey assessed knowledge, attitudes, and compliance regarding standard precautions about health care-associated infections (HAIs) and the associated determinants among healthcare workers (HCWs) in emerge...

    Authors: Cristiana Parmeggiani, Rossella Abbate, Paolo Marinelli and Italo F Angelillo

    Citation: BMC Infectious Diseases 2010 10:35

    Content type: Research article

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  14. Studies have revealed that visiting poultry markets and direct contact with sick or dead poultry are significant risk factors for H5N1 infection, the practices of which could possibly be influenced by people's...

    Authors: Nijuan Xiang, Ying Shi, Jiabing Wu, Shunxiang Zhang, Min Ye, Zhibin Peng, Lei Zhou, Hang Zhou, Qiaohong Liao, Yang Huai, Leilei Li, Zhangda Yu, Xiaowen Cheng, Weike Su, Xiaomin Wu, Hanwu Ma…

    Citation: BMC Infectious Diseases 2010 10:34

    Content type: Research article

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  15. Chikungunya virus (CHIKV) is responsible for major epidemics worldwide. Autochthonous cases were recently reported in several European countries. Acute infection is thought to be monophasic. However reports on...

    Authors: Daniel Ciampi de Andrade, Sylvain Jean, Pierre Clavelou, Radhouane Dallel and Didier Bouhassira

    Citation: BMC Infectious Diseases 2010 10:31

    Content type: Research article

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  16. Norovirus is often transmitted from person-to-person. Transmission may also be food-borne, but only few norovirus outbreak investigations have identified food items as likely vehicles of norovirus transmission...

    Authors: Maria Wadl, Kathrin Scherer, Stine Nielsen, Sabine Diedrich, Lüppo Ellerbroek, Christina Frank, Renate Gatzer, Marina Hoehne, Reimar Johne, Günter Klein, Judith Koch, Jörg Schulenburg, Uta Thielbein, Klaus Stark and Helen Bernard

    Citation: BMC Infectious Diseases 2010 10:30

    Content type: Research article

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  17. Screening and isolation are central components of hospital methicillin-resistant Staphylococcus aureus (MRSA) control policies. Their prevention of patient-to-patient spread depends on minimizing undetected and u...

    Authors: Theodore Kypraios, Philip D O'Neill, Susan S Huang, Sheryl L Rifas-Shiman and Ben S Cooper

    Citation: BMC Infectious Diseases 2010 10:29

    Content type: Research article

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  18. Even though sepsis is one of the common causes of children morbidity and mortality, specific inflammatory markers for identifying sepsis are less studied in children. The main aim of this study was to compare ...

    Authors: Jana Pavare, Ilze Grope, Imants Kalnins and Dace Gardovska

    Citation: BMC Infectious Diseases 2010 10:28

    Content type: Research article

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  19. Human papillomavirus (HPV) infection is a causative factor for cervical cancer. Early detection of high risk HPV types might help to identify women at high risk of cervical cancer. The aim of the present study...

    Authors: Petroula Stamataki, Athanasia Papazafiropoulou, Ioannis Elefsiniotis, Margarita Giannakopoulou, Hero Brokalaki, Eleni Apostolopoulou, Pavlos Sarafis and George Saroglou

    Citation: BMC Infectious Diseases 2010 10:27

    Content type: Research article

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  20. Intrauterine infection is the main contributor to maternal-infantile transmission of HBV. This is a retrospective study of 158 HBsAg-positive pregnant women who delivered children from Jan 1st, 2004 to Dec.31t...

    Authors: Yan Guo, Jianqiong Liu, Liping Meng, Hu Meina and Yukai Du

    Citation: BMC Infectious Diseases 2010 10:26

    Content type: Research article

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  21. In the event of a release of a pathogen such as smallpox, which is human-to-human transmissible and has high associated mortality, a key question is how best to deploy containment and control strategies. Given...

    Authors: Thomas House, Ian Hall, Leon Danon and Matt J Keeling

    Citation: BMC Infectious Diseases 2010 10:25

    Content type: Research article

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  22. Many congenitally cytomegalovirus-infected (cCMV) neonates are at risk for severe consequences, even if they are asymptomatic at birth. The assessment of the viral load in neonatal blood could help in identify...

    Authors: Sandro Binda, Antonella Mammoliti, Valeria Primache, Patrizia Didò, Carlo Corbetta, Fabio Mosca, Lorenza Pugni, Anna Bossi, Cristian Ricci and Maria Barbi

    Citation: BMC Infectious Diseases 2010 10:24

    Content type: Research article

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  23. South Africa remains the country with the greatest burden of HIV-infected individuals and the second highest estimated TB incidence per capita worldwide. Within South Africa, KwaZulu-Natal has one of the highe...

    Authors: Catherine F Houlihan, Portia C Mutevedzi, Richard J Lessells, Graham S Cooke, Frank C Tanser and Marie-Louise Newell

    Citation: BMC Infectious Diseases 2010 10:23

    Content type: Research article

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  24. Pneumococcal conjugate vaccine strategies in GAVI-eligible countries are focusing on infant immunization but this strategy may not be optimal in all settings. We aimed to collect all available population based...

    Authors: Bradford D Gessner, Judith E Mueller and Seydou Yaro

    Citation: BMC Infectious Diseases 2010 10:22

    Content type: Research article

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  25. Tuberculosis (TB), an infectious disease caused by the Mycobacterium tuberculosis is endemic in Madagascar. The capital, Antananarivo is the most seriously affected area. TB had a non-random spatial distribution ...

    Authors: Rindra V Randremanana, Vincent Richard, Fanjasoa Rakotomanana, Philippe Sabatier and Dominique J Bicout

    Citation: BMC Infectious Diseases 2010 10:21

    Content type: Research article

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  26. Persistent symptoms after treatment for neuroborreliosis are common for reasons mainly unknown. These symptoms are often unspecific and could be caused by dysfunctions in endocrine systems, an issue that has n...

    Authors: Ivar Tjernberg, Martin Carlsson, Jan Ernerudh, Ingvar Eliasson and Pia Forsberg

    Citation: BMC Infectious Diseases 2010 10:20

    Content type: Research article

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  27. Human papillomavirus (HPV) and HIV are each responsible for a considerable burden of disease. Interactions between these infections pose substantial public health challenges, especially where HIV prevalence is...

    Authors: Stanley MF Luchters, Davy Vanden Broeck, Matthew F Chersich, Annalene Nel, Wim Delva, Kishor Mandaliya, Christophe E Depuydt, Patricia Claeys, John-Paul Bogers and Marleen Temmerman

    Citation: BMC Infectious Diseases 2010 10:18

    Content type: Research article

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  28. Despite medical advances, mortality in infective endocarditis (IE) is still very high. Previous studies on prognosis in IE have observed conflicting results. The aim of this study was to identify predictors of...

    Authors: Juan Gálvez-Acebal, Jesús Rodríguez-Baño, Francisco J Martínez-Marcos, Jose M Reguera, Antonio Plata, Josefa Ruiz, Manuel Marquez, Jose M Lomas, Javier de la Torre-Lima, Carmen Hidalgo-Tenorio and Arístides de Alarcón

    Citation: BMC Infectious Diseases 2010 10:17

    Content type: Research article

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  29. Extrapulmonary tuberculosis is likely a marker of underlying immune compromise. Our objective was to determine race and sex differences in extrapulmonary tuberculosis risk in order to identify the optimal popu...

    Authors: Christina T Fiske, Marie R Griffin, Holt Erin, Jon Warkentin, Kaltenbach Lisa, Patrick G Arbogast and Timothy R Sterling

    Citation: BMC Infectious Diseases 2010 10:16

    Content type: Research article

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  30. Our understanding of the transmission dynamics of respiratory syncytial virus (RSV) infection will be better informed with improved data on the patterns of shedding in cases not limited only to hospital admiss...

    Authors: Emelda A Okiro, Lisa J White, Mwanajuma Ngama, Patricia A Cane, Graham F Medley and D James Nokes

    Citation: BMC Infectious Diseases 2010 10:15

    Content type: Research article

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  31. Influenza pandemic outbreaks occurred in the US in 1918, 1957, and 1968. Historical evidence suggests that the majority of influenza-related deaths during the 1918 US pandemic were attributable to bacterial pn...

    Authors: Jaime L Rubin, Lisa J McGarry, Keith P Klugman, David R Strutton, Kristen E Gilmore and Milton C Weinstein

    Citation: BMC Infectious Diseases 2010 10:14

    Content type: Research article

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  32. Gonorrhea is a major sexually transmitted disease (STD) in many countries worldwide. The emergence of fluoroquinolone resistance has complicated efforts to control and treat this disease. We report the first s...

    Authors: Loubna Tazi, Marcos Pérez-Losada, Weiming Gu, Yang Yang, Lin Xue, Keith A Crandall and Raphael P Viscidi

    Citation: BMC Infectious Diseases 2010 10:13

    Content type: Research article

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  33. Evidence for protection of preterm born infants from invasive pneumococcal disease (IPD) by 7-valent pneumococcal conjugate vaccination (PCV7) is relatively sparse. Data from randomized trials is based on rela...

    Authors: Simon Rückinger, Mark van der Linden and Rüdiger von Kries

    Citation: BMC Infectious Diseases 2010 10:12

    Content type: Research article

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  34. Currently available tools cannot be used to distinguish between sub-species of the M. tuberculosis complex causing latent tuberculosis (TB) infection. M. africanum causes up to half of TB in West- Africa and its ...

    Authors: Bouke C de Jong, Abdulrahman Hammond, Jacob K Otu, Martin Antonio, Richard A Adegbola and Martin O Ota

    Citation: BMC Infectious Diseases 2010 10:11

    Content type: Research article

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  35. It has been shown previously that administration of Francisella tularensis (Ft) Live Vaccine Strain (LVS) lipopolysaccharide (LPS) protects mice against subsequent challenge with Ft LVS and blunts the pro-inflamm...

    Authors: Saroj K Mohapatra, Leah E Cole, Clive Evans, Bruno W Sobral, Josep Bassaganya-Riera, Raquel Hontecillas, Stefanie N Vogel and Oswald R Crasta

    Citation: BMC Infectious Diseases 2010 10:10

    Content type: Research article

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  36. Few studies have assessed long term persisting immunity against hepatitis B virus (HBV) in children vaccinated during infancy with combined vaccines containing recombinant HBV surface antigen (HBs). We assesse...

    Authors: Michael Steiner, Gunasekaran Ramakrishnan, Britta Gartner, Olivier Van Der Meeren, Jeanne-Marie Jacquet and Volker Schuster

    Citation: BMC Infectious Diseases 2010 10:9

    Content type: Research article

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  37. Influenza immunisation for healthcare workers is encouraged to protect their often vulnerable patients but also due to a perceived higher risk for influenza. We aimed to compare the risk of influenza infection...

    Authors: Chris J Williams, Brunhilde Schweiger, Genia Diner, Frank Gerlach, Frank Haaman, Gérard Krause, Albert Nienhaus and Udo Buchholz

    Citation: BMC Infectious Diseases 2010 10:8

    Content type: Research article

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  38. We have previously reported a HIV-1 subtype A infection in a community of injection drug users (IDUs) in Karachi, Pakistan. We now show that this infection among the IDUs may have originated from a single source.

    Authors: Mohammad A Rai, Vivek R Nerurkar, Suhail Khoja, Saeed Khan, Richard Yanagihara, Arish Rehman, Shahana U Kazmi and Syed H Ali

    Citation: BMC Infectious Diseases 2010 10:7

    Content type: Research article

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  39. Induction-maintenance therapy is a treatment regime where patients are prescribed an intense course of treatment for a short period of time (the induction phase), followed by a simplified long-term regimen (ma...

    Authors: Rachelle E Miron and Robert J Smith

    Citation: BMC Infectious Diseases 2010 10:6

    Content type: Research article

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  40. A pandemic novel H1N1 swine-origin influenza virus has emerged. Most recently the World Health Organization has announced that in a country-dependent fashion, up to 15% of cases may require hospitalization, of...

    Authors: Tom Reichert, Gerardo Chowell, Hiroshi Nishiura, Ronald A Christensen and Jonathan A McCullers

    Citation: BMC Infectious Diseases 2010 10:5

    Content type: Debate

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  41. Toxoplasmosis is an important zoonotic parasitic disease worldwide. In immune competent individuals, Toxoplasma gondii preferentially infects tissues of central nervous systems, which might be an adding factor of...

    Authors: Yue Xiao, Jigang Yin, Ning Jiang, Mei Xiang, Lili Hao, Huijun Lu, Hong Sang, Xianying Liu, Huiji Xu, Johan Ankarklev, Johan Lindh and Qijun Chen

    Citation: BMC Infectious Diseases 2010 10:4

    Content type: Research article

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  42. Influenza is a major cause of morbidity and hospitalization among children. While less often reported in adults, gastrointestinal symptoms have been associated with influenza in children, including abdominal p...

    Authors: Charisma Dilantika, Endang R Sedyaningsih, Matthew R Kasper, Magdarina Agtini, Erlin Listiyaningsih, Timothy M Uyeki, Timothy H Burgess, Patrick J Blair and Shannon D Putnam

    Citation: BMC Infectious Diseases 2010 10:3

    Content type: Research article

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  43. Valganciclovir, the oral prodrug of ganciclovir, has been demonstrated equivalent to iv ganciclovir for CMV disease treatment in solid organ transplant recipients. Variability in ganciclovir exposure achieved ...

    Authors: Nancy Perrottet, Oriol Manuel, Frédéric Lamoth, Jean-Pierre Venetz, Roland Sahli, Laurent A Decosterd, Thierry Buclin, Manuel Pascual and Pascal Meylan

    Citation: BMC Infectious Diseases 2010 10:2

    Content type: Research article

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  44. Bacteremia and systemic complications both play important roles in brain pathophysiological alterations and the outcome of pneumococcal meningitis. Their individual contributions to the development of brain da...

    Authors: Christian Østergaard, Stephen L Leib, Ian Rowland and Christian T Brandt

    Citation: BMC Infectious Diseases 2010 10:1

    Content type: Research article

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  45. The incidence of tuberculosis (TB) in developed countries has decreased since the 1990s, reflecting worldwide efforts to identify and treat TB according to WHO recommendations. However TB remains an important ...

    Authors: Omar Kherad, François R Herrmann, Jean-Pierre Zellweger, Thierry Rochat and Jean-Paul Janssens

    Citation: BMC Infectious Diseases 2009 9:217

    Content type: Research article

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  46. Tuberculosis is one of the most prominent health problems in the world, causing 1.75 million deaths each year. Rapid clinical diagnosis is important in patients who have co-morbidities such as Human Immunodefi...

    Authors: Luciene C Scherer, Rosa D Sperhacke, Antonio Ruffino-Netto, Maria LR Rossetti, Claudia Vater, Paul Klatser and Afrânio L Kritski

    Citation: BMC Infectious Diseases 2009 9:216

    Content type: Research article

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