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  1. Sexually transmitted and genital infections in pregnancy are associated with an increased risk of adverse maternal and neonatal health outcomes. High prevalences of sexually transmitted infections have been id...

    Authors: Steven G. Badman, Lisa M. Vallely, Pamela Toliman, Grace Kariwiga, Bomesina Lote, William Pomat, Caroline Holmer, Rebecca Guy, Stanley Luchters, Chris Morgan, Suzanne M. Garland, Sepehr Tabrizi, David Whiley, Stephen J. Rogerson, Glen Mola, Handan Wand…
    Citation: BMC Infectious Diseases 2016 16:250
    Content type: Research article Published on:

  2. Prisoners represent a vulnerable population for blood-borne and sexually transmitted infections which can potentially lead to liver fibrosis and ultimately cirrhosis. However, little is known about the prevale...

    Authors: Antoine Jaquet, Gilles Wandeler, Judicaël Tine, Claver A. Dagnra, Alain Attia, Akouda Patassi, Abdoulaye Ndiaye, Victor de Ledinghen, Didier K. Ekouevi, Moussa Seydi and François Dabis
    Citation: BMC Infectious Diseases 2016 16:249
    Content type: Research article Published on:

  3. Human dirofilariosis is still a little known infection even in endemic areas. Dirofilariosis is zoonotic infection usually abortive in humans; instead, we report a very rare case (the 4th in the world), the fi...

    Authors: Lucia Fontanelli Sulekova, Simona Gabrielli, Maurizio De Angelis, Giovanni L. Milardi, Carlo Magnani, Biancamaria Di Marco, Gloria Taliani and Gabriella Cancrini
    Citation: BMC Infectious Diseases 2016 16:248
    Content type: Case report Published on:

  4. Pneumonia is a primary cause of morbidity and mortality in infectious disease, and increasing antimicrobial resistance has raised concerns of treatment failure. Therefore, we evaluated the value of a blood cul...

    Authors: Eun Young Heo, Sue Shin, Hee Soon Chung, Yun-Jeong Jeong, So Hee Oh and Deog Kyeom Kim
    Citation: BMC Infectious Diseases 2016 16:247
    Content type: Research article Published on:

  5. Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IA...

    Authors: Maira Bholla, Neema Kapalata, Edward Masika, Hassan Chande, Levan Jugheli, Mohamed Sasamalo, Tracy R. Glass, Hans-Peter Beck and Klaus Reither
    Citation: BMC Infectious Diseases 2016 16:246
    Content type: Research article Published on:

  6. Q fever in Kenya is poorly reported and its surveillance is highly neglected. Standard empiric treatment for febrile patients admitted to hospitals is antimalarials or penicillin-based antibiotics, which have ...

    Authors: J. Njeru, K. Henning, M. W. Pletz, R. Heller, C. Forstner, S. Kariuki, E. M. Fèvre and H. Neubauer
    Citation: BMC Infectious Diseases 2016 16:244
    Content type: Research article Published on:

  7. Although N95 filtering facepiece respirators and medical masks are commonly used for protection against respiratory infections in healthcare settings, more clinical evidence is needed to understand the optimal...

    Authors: Lewis J. Radonovich Jr., Mary T. Bessesen, Derek A. Cummings, Aaron Eagan, Charlotte Gaydos, Cynthia Gibert, Geoffrey J. Gorse, Ann-Christine Nyquist, Nicholas G. Reich, Maria Rodrigues-Barradas, Connie Savor-Price, Ronald E. Shaffer, Michael S. Simberkoff and Trish M. Perl
    Citation: BMC Infectious Diseases 2016 16:243
    Content type: Study protocol Published on:

  8. The cost and complexity of current approaches to therapeutic drug monitoring during tuberculosis (TB) therapy limits widespread use in areas of greatest need. We sought to determine whether urine colorimetry c...

    Authors: Isaac Zentner, Hans P. Schlecht, Lorna Khensouvann, Neo Tamuhla, Michele Kutzler, Vijay Ivaturi, Jotam G. Pasipanodya, Tawanda Gumbo, Charles A. Peloquin, Gregory P. Bisson and Christopher Vinnard
    Citation: BMC Infectious Diseases 2016 16:242
    Content type: Research article Published on:

  9. Human immunodeficiency virus (HIV) infection leads to more rapid progression of hepatitis C virus (HCV)-related liver fibrosis, which could be linked to differences in the severity of liver inflammation among ...

    Authors: François M. J. Lamoury, Behzad Hajarizadeh, Elizabeth Keoshkerian, Jordan J. Feld, Janaki Amin, Suzy Teutsch, Gail V. Matthews, Margaret Hellard, Gregory J. Dore, Andrew R. Lloyd, Tanya L. Applegate and Jason Grebely
    Citation: BMC Infectious Diseases 2016 16:241
    Content type: Research article Published on:

  10. Late-appearing anaemia (LAA) following treatment with artemisinins for severe malaria has been reported and well described, but there are limited clinical and parasitological data on LAA in African children wi...

    Authors: Akintunde Sowunmi, Kazeem Akano, Adejumoke I. Ayede, Godwin Ntadom, Temitope Aderoyeje, Elsie O. Adewoye and Bayo Fatunmbi
    Citation: BMC Infectious Diseases 2016 16:240
    Content type: Research article Published on:

  11. The objective of this ambispective study was to determine outcomes and associated factors for adult patients with confirmed septic arthritis (SA).

    Authors: Julien Ferrand, Youssef El Samad, Benoit Brunschweiler, Franck Grados, Nassima Dehamchia-Rehailia, Alice Séjourne, Jean-Luc Schmit, Antoine Gabrion, Patrice Fardellone and Julien Paccou
    Citation: BMC Infectious Diseases 2016 16:239
    Content type: Research article Published on:

  12. It is known that mobile phones may play a role in microorganism transmission. The aim of this study was to analyze the relationship between the number of Candida genera/species isolated from samples collected fro...

    Authors: Anna Kordecka, Elżbieta Krajewska-Kułak, Cecylia Łukaszuk, Bogumiła Kraszyńska and Wojciech Kułak
    Citation: BMC Infectious Diseases 2016 16:238
    Content type: Research article Published on:

  13. The endgame for polio eradication includes coordinated global cessation of oral poliovirus vaccine (OPV), starting with the cessation of vaccine containing OPV serotype 2 (OPV2) by switching all trivalent OPV ...

    Authors: Radboud J. Duintjer Tebbens, Lee M. Hampton and Kimberly M. Thompson
    Citation: BMC Infectious Diseases 2016 16:237
    Content type: Research article Published on:

  14. Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in young children in both the community and hospital setting.

    Authors: Regina Oladokun, Rudzani Muloiwa, Nei-yuan Hsiao, Ziyaad Valley-Omar, James Nuttall and Brian Eley
    Citation: BMC Infectious Diseases 2016 16:236
    Content type: Research article Published on:

  15. Blood cultures are commonly employed to identify bacterial pathogens causing sepsis. PCR assays to diagnose septicemia require extraction of bacterial DNA from blood samples and thus, delay the initiation of a...

    Authors: Ngo Tat Trung, Tran Thi Thu Hien, Tran Thi Thanh Huyen, Dao Thanh Quyen, Trinh Van Son, Phan Quoc Hoan, Nguyen Thi Kim Phuong, Tran Thi Lien, Mai Thanh Binh, Hoang Van Tong, Christian G. Meyer, Thirumalaisamy P. Velavan and Le Huu Song
    Citation: BMC Infectious Diseases 2016 16:235
    Content type: Research article Published on:

  16. We report herein a case of fecal microbiota transplantation (FMT) used for severe Clostridium difficile infection for a 65-year-old Lebanese man who underwent left ventricular assist device implantation. To the b...

    Authors: Zeina Z. Berro, Righab H. Hamdan, Israa H. Dandache, Mohamad N. Saab, Hussein H. Karnib and Mahmoud H. Younes
    Citation: BMC Infectious Diseases 2016 16:234
    Content type: Case report Published on:

  17. Major outbreaks of hand, foot and mouth disease (HFMD) have been reported in China since 2008, posing a great threat to the health of children. Although many studies have examined the effect of meteorological ...

    Authors: Chao Wang, Kai Cao, Yingjie Zhang, Liqun Fang, Xia Li, Qin Xu, Fangfang Huang, Lixin Tao, Jin Guo, Qi Gao and Xiuhua Guo
    Citation: BMC Infectious Diseases 2016 16:233
    Content type: Research article Published on:

  18. The early identification of patients at risk of dying from community-acquired pneumonia (CAP) is critical for their treatment and for defining hospital resource consumption. Mid-regional pro-adrenomedullin (MR...

    Authors: Dan Liu, Lixin Xie, Haiyan Zhao, Xueyao Liu and Jie Cao
    Citation: BMC Infectious Diseases 2016 16:232
    Content type: Research article Published on:

  19. The endgame for polio eradication involves coordinated global cessation of oral poliovirus vaccine (OPV) with cessation of serotype 2 OPV (OPV2 cessation) implemented in late April and early May 2016 and cessa...

    Authors: Radboud J. Duintjer Tebbens, Lee M. Hampton and Kimberly M. Thompson
    Citation: BMC Infectious Diseases 2016 16:231
    Content type: Research article Published on:

  20. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinico-radiological syndrome characterized by transient mild symptoms of encephalopathy and a reversible lesion in the...

    Authors: Zhe-Feng Yuan, Jue Shen, Shan-Shan Mao, Yong-Lin Yu, Lu Xu, Pei-Fang Jiang, Feng Gao and Zhe-Zhi Xia
    Citation: BMC Infectious Diseases 2016 16:230
    Content type: Case report Published on:

  21. The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was established in 2008 to answer strategic questions about schistosomiasis control. For programme managers, a high-priority quest...

    Authors: Amara E. Ezeamama, Chun-La He, Ye Shen, Xiao-Ping Yin, Sue C. Binder, Carl H. Campbell Jr., Stephen Rathbun, Christopher C. Whalen, Eliézer K. N’Goran, Jürg Utzinger, Annette Olsen, Pascal Magnussen, Safari Kinung’hi, Alan Fenwick, Anna Phillips, Josefo Ferro…
    Citation: BMC Infectious Diseases 2016 16:229
    Content type: Research article Published on:

  22. This study was designed to determine the Human papillomavirus (HPV) prevalence and its distribution of genotypes in various regions of Yunnan Province, China.

    Authors: Zulqarnain Baloch, Yuanyue Li, Tao Yuan, Yue Feng, Yanqing Liu, Wenlin Tai, Li Liu, Binghui Wang, A-mei Zhang, Xiaomei Wu and Xueshan Xia
    Citation: BMC Infectious Diseases 2016 16:228
    Content type: Research article Published on:

  23. Patients with chronic heart failure (CHF) may experience higher mortality of Staphylococcus aureus bacteremia (SAB) than patients without CHF due to insufficient cardiovascular responses during systemic infection...

    Authors: Jesper Smit, Kasper Adelborg, Reimar Wernich Thomsen, Mette Søgaard and Henrik Carl Schønheyder
    Citation: BMC Infectious Diseases 2016 16:227
    Content type: Research article Published on:

  24. There is a marked variation in both antibiotic prescribing practice and urine sampling rates for diagnostic microbiology across general practices in England. To help understand factors driving this variation, ...

    Authors: Dean Ironmonger, Obaghe Edeghere, Savita Gossain and Peter M. Hawkey
    Citation: BMC Infectious Diseases 2016 16:226
    Content type: Research article Published on:

  25. Cervical cancer is the most common female cancer in Rwanda that, in 2011, became the first African country to implement a national vaccination programme against human papillomavirus (HPV).

    Authors: Fidele Ngabo, Silvia Franceschi, Iacopo Baussano, M. Chantal Umulisa, Peter J. F. Snijders, Anne M. Uyterlinde, Fulvio Lazzarato, Vanessa Tenet, Maurice Gatera, Agnes Binagwaho and Gary M. Clifford
    Citation: BMC Infectious Diseases 2016 16:225
    Content type: Research article Published on:

  26. Prior studies suggested that vancomycin may be inferior to β-lactams for the empiric treatment of methicillin-susceptible S. aureus (MSSA) bacteremia. We assessed whether empiric therapy with β-lactams compared t...

    Authors: Davie Wong, Titus Wong, Marc Romney and Victor Leung
    Citation: BMC Infectious Diseases 2016 16:224
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2020 20:568

  27. Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. There are however few longitudinal studies on the changes in case fatality rate of IPD in recent years. We ...

    Authors: Åsa Askim, Arne Mehl, Julie Paulsen, Andrew T. DeWan, Didrik F. Vestrheim, Bjørn Olav Åsvold, Jan Kristian Damås and Erik Solligård
    Citation: BMC Infectious Diseases 2016 16:223
    Content type: Research article Published on:

  28. Worldwide, there is a wealth of literature examining patient-level risk factors for methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia. At the hospital-level it is generally accepted that MRSA bactera...

    Authors: Cheryl L. Gibbons, Bram A. D. van Bunnik, Oliver Blatchford, Chris Robertson, Thibaud Porphyre, Laura Imrie, Julie Wilson, J. Ross Fitzgerald, Mark E. J. Woolhouse and Margo E. Chase-Topping
    Citation: BMC Infectious Diseases 2016 16:222
    Content type: Research article Published on:

  29. Cystoisosporiasis is an opportunistic infection seen more commonly in patients with acquired immunodeficiency syndrome. Although uncommon, Cystoisospora infection can occur in immunocompetent individuals but tend...

    Authors: Sze-Ann Woon, Rongchang Yang, Una Ryan, Peter Boan and David Prentice
    Citation: BMC Infectious Diseases 2016 16:221
    Content type: Case report Published on:

  30. The aim of this study was to assess the burden of respiratory disease, considering the influenza A pandemic season (H1N1pdm09), within the Brazilian Network for Surveillance of Severe Maternal Morbidity, and f...

    Authors: L. C. Pfitscher, J. G. Cecatti, R. C. Pacagnella, S. M. Haddad, M. A. Parpinelli, J. P. Souza, S. M. Quintana, F. G. Surita, M. H. Sousa and M. L. Costa
    Citation: BMC Infectious Diseases 2016 16:220
    Content type: Research article Published on:

  31. In epidemic regions of the world, brucellosis is a reemerging zoonosis with minimal mortality but is a serious public hygiene problem. Currently, there are various methods for brucellosis diagnosis, however fe...

    Authors: Dehui Yin, Li Li, Xiuling Song, Han Li, Juan Wang, Wen Ju, Xiaofeng Qu, Dandan Song, Yushen Liu, Xiangjun Meng, Hongqian Cao, Weiyi Song, Rizeng Meng, Jinhua Liu, Juan Li and Kun Xu
    Citation: BMC Infectious Diseases 2016 16:219
    Content type: Research article Published on:

  32. In order to better understand respiratory syncytial virus (RSV) epidemiology and burden in tropical Africa, optimal case definitions for detection of RSV cases need to be identified.

    Authors: Bryan O. Nyawanda, Joshua A. Mott, Henry N. Njuguna, Lilian Mayieka, Sammy Khagayi, Reuben Onkoba, Caroline Makokha, Nancy A. Otieno, Godfrey M. Bigogo, Mark A. Katz, Daniel R. Feikin and Jennifer R. Verani
    Citation: BMC Infectious Diseases 2016 16:218
    Content type: Research article Published on:

  33. The effectiveness of Long-Lasting Insecticidal Nets and Indoor Residual Spraying in malaria vector control is threatened by vector resistance to insecticides. Knowledge of mosquito habitats and patterns of ins...

    Authors: Josiane Etang, Arthur Mbida Mbida, Patrick Ntonga Akono, Jerome Binyang, Carole Else Eboumbou Moukoko, Leopold Gustave Lehman, Parfait Awono-Ambene, Abdou Talipouo, Wolfgang Ekoko Eyisab, Darus Tagne, Romeo Tchoffo, Lucien Manga and Remy Mimpfoundi
    Citation: BMC Infectious Diseases 2016 16:217
    Content type: Research article Published on:

  34. Increasing pneumococcal resistance to commonly used antibiotics and multidrug resistance is a serious public health concern. Data on distribution of resistant Streptococcus pneumoniae (SPn) strains among children...

    Authors: Indrė Stacevičienė, Sigita Petraitienė, Daiva Vaičiūnienė, Tomas Alasevičius, Jūratė Kirslienė and Vytautas Usonis
    Citation: BMC Infectious Diseases 2016 16:216
    Content type: Research article Published on:

  35. Modelling studies suggest that workplaces may be important sites of Mycobacterium tuberculosis transmission in high burden countries today. Contemporary data on tuberculosis by occupation from these settings are ...

    Authors: Charlotte Jackson, Joanna H. Mostowy, Helen R. Stagg, Ibrahim Abubakar, Nick Andrews and Tom A. Yates
    Citation: BMC Infectious Diseases 2016 16:215
    Content type: Research article Published on:

  36. In Mozambique, there is limited data regarding the monitoring of Tuberculosis (TB) treatment results and determinants of adverse outcomes under routine surveillance conditions. The objectives of this study wer...

    Authors: Alberto L. García-Basteiro, Durval Respeito, Orvalho J. Augusto, Elisa López-Varela, Charfudin Sacoor, Victor G. Sequera, Aina Casellas, Quique Bassat, Ivan Manhiça, Eusebio Macete, Frank Cobelens and Pedro L. Alonso
    Citation: BMC Infectious Diseases 2016 16:214
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Infectious Diseases 2016 16:603

  37. Migrant travellers who return to their country of origin to visit family and friends (VFR) are less likely to seek travel-related medical care and are less likely to adhere to recommended medications and trave...

    Authors: Holly Seale, Rajneesh Kaur, Abela Mahimbo, C. Raina MacIntyre, Nicholas Zwar, Mitchell Smith, Heather Worth and Anita E Heywood
    Citation: BMC Infectious Diseases 2016 16:213
    Content type: Research article Published on:

  38. The purpose of this study is to explore the correlations of interleukin 36 (IL-36) and Soluble B7-H3 (sB7-H3) levels in bronchoalveolar lavage fluid (BALF) with clinical characteristics and laboratory findings.

    Authors: Zhengrong Chen, Xin Zhao, Xinxing Zhang, Guangbo Zhang, Huiming Sun, Wujun Jiang, Yuqing Wang, Canhong Zhu, Wei Ji and Yongdong Yan
    Citation: BMC Infectious Diseases 2016 16:212
    Content type: Research article Published on:

  39. Urinary tract infection (UTI) is a widespread infectious disease in humans. Urine culture, a huge workload in the microbiology laboratory, is still the standard diagnostic test for UTI, but most of the culture...

    Authors: Bijan Moshaver, Foppie de Boer, Heidi van Egmond-Kreileman, Ellen Kramer, Coen Stegeman and Paul Groeneveld
    Citation: BMC Infectious Diseases 2016 16:211
    Content type: Research article Published on:

  40. Louse-borne relapsing fever (LBRF) is a neglected disease that has been restricted to East Africa for many decades. Several cases in refugees from the Horn of Africa have been recently diagnosed in four Europe...

    Authors: Michael Osthoff, Adrian Schibli, Davide Fadini, Pietro Lardelli and Daniel Goldenberger
    Citation: BMC Infectious Diseases 2016 16:210
    Content type: Case report Published on:

  41. Paracoccidioidomycosis, a chronic granulomatous fungal disease caused by Paracoccidioides brasiliensis yeast cells affects mainly rural workers, albeit recently cases in immunosuppressed individuals has been repo...

    Authors: Rosaria Di Gangi, Thiago Alves da Costa, Rodolfo Thomé, Gabriela Peron, Eva Burger and Liana Verinaud
    Citation: BMC Infectious Diseases 2016 16:209
    Content type: Research article Published on:

  42. Antibiotic overuse is driving the emergence of antibiotic resistance worldwide. Good data on prescribing behaviours of healthcare providers are needed to support antimicrobial stewardship initiatives. This stu...

    Authors: Norazida Ab Rahman, Cheong Lieng Teng and Sheamini Sivasampu
    Citation: BMC Infectious Diseases 2016 16:208
    Content type: Research article Published on:

  43. Mycobacterium abscessus complex (MABC) is the most drug resistant of the mycobacterial pathogens. M. abscessus subsp. abscessus encodes a functional erythromycin ribosomal methylase ge...

    Authors: Su-Young Kim, Sung Jae Shin, Byeong-Ho Jeong and Won-Jung Koh
    Citation: BMC Infectious Diseases 2016 16:207
    Content type: Case report Published on:

  44. The incidence of hand, foot, and mouth disease (HFMD) is extremely high, and has constituted a huge disease burden throughout Beijing in recent years. This study aimed to determine the spatiotemporal distribut...

    Authors: Haikun Qian, Da Huo, Xiaoli Wang, Lei Jia, Xitai Li, Jie Li, Zhiyong Gao, Baiwei Liu, Yi Tian, Xiaona Wu and Quanyi Wang
    Citation: BMC Infectious Diseases 2016 16:206
    Content type: Research article Published on:

  45. Pyrazinamide (PZA) plays an essential part in the shortened six-month tuberculosis (TB) treatment course due to its activity against slow-growing and non-replicating organisms. We tested whether PZA preferenti...

    Authors: Steven T. Pullan, Jon C. Allnutt, Rebecca Devine, Kim A. Hatch, Rose E. Jeeves, Charlotte L. Hendon-Dunn, Philip D. Marsh and Joanna Bacon
    Citation: BMC Infectious Diseases 2016 16:205
    Content type: Research article Published on:

  46. Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI. However, l...

    Authors: Andreas Sandgren, Marije Vonk Noordegraaf-Schouten, Femke van Kessel, Anke Stuurman, Anouk Oordt-Speets and Marieke J. van der Werf
    Citation: BMC Infectious Diseases 2016 16:204
    Content type: Research article Published on:

  47. The impact of sink location on hand washing compliance after contact with patients with Clostridium difficile infection (CDI) is poorly understood. The aim of this study is to determine the location of hand wash ...

    Authors: Alexander Deyneko, Fernanda Cordeiro, Laurie Berlin, Debby Ben-David, Silvana Perna and Yves Longtin
    Citation: BMC Infectious Diseases 2016 16:203
    Content type: Research article Published on:

  48. Hepatitis C virus (HCV) treatment uptake globally is low. A barrier to treatment is the necessity to attend specialists, usually in a tertiary hospital. We investigate the literature to assess the effect of pr...

    Authors: Amanda J. Wade, Vanessa Veronese, Margaret E. Hellard and Joseph S. Doyle
    Citation: BMC Infectious Diseases 2016 16:202
    Content type: Research article Published on:

  49. Rapid diagnostic tests (RDTs) have been commercialized in order to help physicians in dengue diagnosis. Until recently, only blood samples were used for those tests but it has been shown in several studies tha...

    Authors: Anne-Claire Andries, Veasna Duong, Sivuth Ong, Sopheaktra Ros, Anavaj Sakuntabhai, Paul Horwood, Philippe Dussart and Philippe Buchy
    Citation: BMC Infectious Diseases 2016 16:201
    Content type: Research article Published on:

  50. Interleukin-33 (IL-33) and ST2 have been demonstrated to be associated with liver damage. However, their potential value in hepatitis B virus (HBV) infection remains unknown. This study was designed to investi...

    Authors: Shu-Ling Huan, Ji-Guang Zhao, Zhen-Li Wang, Shuai Gao and Kai Wang
    Citation: BMC Infectious Diseases 2016 16:200
    Content type: Research article Published on:

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