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  1. Drug-resistant tuberculosis (TB) continues to be a public health threat. There are few studies on transmission and genotyping of MDR-TB family households in China. This study aimed to investigate transmission ...

    Authors: Jun Chen, Lifeng Chen, Meng Zhou, Gang Wu, Fenglian Yi, Chen Jiang, Qionghong Duan and Meilan Zhou
    Citation: BMC Infectious Diseases 2022 22:192
    Content type: Research Published on:

  2. People with bacteriologically confirmed pulmonary tuberculosis require sputum smear monitoring at 2, 5, and 6 months to establish treatment outcomes. However, there is limited information about sputum smear mo...

    Authors: Ronald Nsubuga, Norbert Adrawa, Stephen Okoboi, Alimah Komuhangi and Jonathan Izudi
    Citation: BMC Infectious Diseases 2022 22:191
    Content type: Research Published on:

  3. After 40 years of its starting, the HIV epidemic in Brazilian Amazon region remains on an increasing trend. The young men who have sex with men (MSM) have been the most impacted by the HIV in the last decade. ...

    Authors: Iaron Leal Seabra, Andrey Oeiras Pedroso, Taymara Barbosa Rodrigues, Glenda Roberta Oliveira Naiff Ferreira, Ana Lucia da Silva Ferreira, Ricardo Alexandre Arcêncio, Dulce Gomes, Richardson Augusto Rosendo da Silva and Eliã Pinheiro Botelho
    Citation: BMC Infectious Diseases 2022 22:190
    Content type: Research Published on:

  4. Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a common pathogen that usually causes bacteraemia, osteomyelitis, as well as skin and soft tissue infections. However, deep venous throm...

    Authors: Mei Lu, Meijiao Fu, Yanhong Zhang, Tong Shen, Hui Xie and Dengli Liu
    Citation: BMC Infectious Diseases 2022 22:189
    Content type: Case report Published on:

  5. Mitochondrial myopathy caused by the long-term use of nucleos(t)ide analogue in patients with chronic hepatitis B (CHB) is mostly characterized by myasthenia and myalgia. Cases with respiratory failure as the ...

    Authors: Xiao Lin, Aixin Song, Sujun Zheng and Xinyue Chen
    Citation: BMC Infectious Diseases 2022 22:188
    Content type: Case report Published on:

  6. While several studies aimed to identify risk factors for severe COVID-19 cases to better anticipate intensive care unit admissions, very few have been conducted on self-reported patient symptoms and characteri...

    Authors: Pablo Diaz Badial, Hugo Bothorel, Omar Kherad, Philippe Dussoix, Faustine Tallonneau Bory and Majd Ramlawi
    Citation: BMC Infectious Diseases 2022 22:187
    Content type: Research Published on:

  7. Poor antiretroviral therapy (ART) adherence is a challenge to containing the spread of HIV. This is an especially difficult challenge in conflict and post-conflict settings. This study investigates the relatio...

    Authors: Emily Coard, Daniel Oliver and Felix Monday
    Citation: BMC Infectious Diseases 2022 22:186
    Content type: Research Published on:

  8. Severe acute respiratory syndrome 2 (SARS-CoV-2) pandemic has had a heavy impact on national health system, especially in the first wave. That impact hit principally the intensive care units (ICUs). The large ...

    Authors: Gianluca Zuglian, Diego Ripamonti, Alessandra Tebaldi, Marina Cuntrò, Ivano Riva, Claudio Farina and Marco Rizzi
    Citation: BMC Infectious Diseases 2022 22:185
    Content type: Research Published on:

  9. Iran was one of the first countries to be affected by COVID-19. Identifying factors associated with the severity of COVID-19 is effective in disease management. This study investigated the epidemiological and ...

    Authors: Seyed Mohammad Hashemi-Shahri, Seyed Mohammad Nasiraldin Tabatabaei, Alireza Ansari-Moghaddam, Mahdi Mohammadi, Hassan Okati-Aliabad, Seyed Mehdi Tabatabaei, Hossein Ansari, Mohammadhadi Abbasi, Khodadad Sheikhzadeh, Mehdi Zanganeh Baygi, Majid Sartipi, Sharareh Sanei-Sistani, Ali Reza Salimi Khorashad, Fatemeh Ansari-Moghadam, Neda Torab, Tahereh Khalili…
    Citation: BMC Infectious Diseases 2022 22:184
    Content type: Research article Published on:

  10. Pseudomembranous necrotizing laryngotracheobronchitis refers to an acute diffuse necrotizing inflammation in the mucosa of the larynx, trachea, and bronchus. It often occurs in infants and children having vira...

    Authors: Wu Lei, Zhang Fei-Zhou, Chen Jing, Li Shu-Xian, Wu Xi-Ling and Tang Lan-Fang
    Citation: BMC Infectious Diseases 2022 22:183
    Content type: Case report Published on:

  11. SARS-CoV-2 is the major cause of infections in humans since December 2019 and is top of the global health concern currently. Streptococcus pneumoniae is one of the leading pathogens of invasive bacterial diseases...

    Authors: Katarzyna Guziejko, Piotr Czupryna, Ewa Katarzyna Zielenkiewicz-Madejska and Anna Moniuszko-Malinowska
    Citation: BMC Infectious Diseases 2022 22:182
    Content type: Case report Published on:

  12. Chlamydia abortus is generally considered to cause abortion, stillbirth, and gestational sepsis in pregnant women, but it’s rare in bloodstream infection and pneumonia.

    Authors: Changjun Zhu, Minjie Lv, Jianling Huang, Changwen Zhang, Lixu Xie, Tianming Gao, Bo Han, Wenjing Wang and Ganzhu Feng
    Citation: BMC Infectious Diseases 2022 22:181
    Content type: Case report Published on:

  13. Health care workers (HCW) are at increased risk of TB infection due to their close contact with infected patients with active TB. The objectives of the study were (1) to assess the prevalence of LTBI among HCW...

    Authors: Caroline Corbett, Gulmira Kalmambetova, Nagira Umetalieva, Sevim Ahmedov, Uladzimir Antonenka, Bakyt Myrzaliev, Evgeni Sahalchyk, Monica Vogel, Abdylat Kadyrov and Harald Hoffmann
    Citation: BMC Infectious Diseases 2022 22:180
    Content type: Research article Published on:

  14. Vaccines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being promoted worldwide. In this study, we analyzed the relationship between adverse...

    Authors: Ryuta Urakawa, Emiko Tanaka Isomura, Kazuhide Matsunaga, Kazumi Kubota and Miho Ike
    Citation: BMC Infectious Diseases 2022 22:179
    Content type: Research Published on:

  15. Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the v...

    Authors: Joseph E. Ebinger, Roy Lan, Matthew Driver, Nancy Sun, Patrick Botting, Eunice Park, Tod Davis, Margo B. Minissian, Bernice Coleman, Richard Riggs, Pamela Roberts and Susan Cheng
    Citation: BMC Infectious Diseases 2022 22:178
    Content type: Research article Published on:

  16. Understanding the extent of viral hepatitis burden in specific subgroups, such as pregnant women and people living with HIV/AIDS (PLWHA), and their geographic distribution is essential for evidence-informed po...

    Authors: Phearavin Pheng, Laurence Meyer, Olivier Ségéral, Phalla Chea, Siyan Yi, Sovannary Tuot, John M. Kaldor and Vonthanak Saphonn
    Citation: BMC Infectious Diseases 2022 22:177
    Content type: Research Published on:

  17. In 2015, Botswana introduced quadrivalent human papillomavirus (HPV) vaccine for girls aged 9–13 years. To establish a baseline HPV prevalence for future HPV vaccine impact monitoring, we evaluated HPV prevale...

    Authors: Nancy McClung, Anikie Mathoma, Julia W. Gargano, Naledi Gape Nyepetsi, Troy D. Querec, Juanita Onyekwuluje, Madisa Mine, Chelsea Morroni, Rebecca Luckett, Lauri E. Markowitz and Doreen Ramogola-Masire
    Citation: BMC Infectious Diseases 2022 22:176
    Content type: Research Published on:

  18. Indwelling urinary catheters are commonly used in hospitalized patients, which can lead to the development of urinary catheter complications, including catheter-associated urinary tract infection (CAUTI). Limi...

    Authors: Kohta Katayama, Jennifer Meddings, Sanjay Saint, Karen E. Fowler, David Ratz, Yasuaki Tagashira, Yumi Kawamura, Tatsuya Fujikawa, Sho Nishiguchi, Naomi Kayauchi, Nobumasa Takagaki, Yasuharu Tokuda and Akira Kuriyama
    Citation: BMC Infectious Diseases 2022 22:175
    Content type: Research Published on:

  19. Globally, key subpopulations such as healthcare workers (HCW) may have a higher risk of contracting SARS-CoV-2. In Uganda, limited access to Personal Protective Equipment and lack of clarity on the extent/patt...

    Authors: Charles Ssuuna, Ronald Moses Galiwango, Edward Nelson Kankaka, Joseph Kagaayi, Anthony Ndyanabo, Godfrey Kigozi, Gertrude Nakigozi, Tom Lutalo, Robert Ssekubugu, John Bosco Wasswa, Anthony Mayinja, Martina Cathy Nakibuuka, Samiri Jamiru, John Baptist Oketch, Edward Muwanga, Larry William Chang…
    Citation: BMC Infectious Diseases 2022 22:174
    Content type: Research Published on:

  20. Prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection with high mortality has attached physicians' attention. High visceral adipose tissue (VAT) and high subcutaneous adipose tissu...

    Authors: Piaopiao Ying, Jiajing Chen, Yinchai Ye, Jianzhong Ye and Weiyang Cai
    Citation: BMC Infectious Diseases 2022 22:173
    Content type: Research article Published on:

  21. To investigate the multi-drug resistant bacteria (MDRB) colonization rate in hematological patients hospitalized for any cause using a multi-body-site surveillance approach, and determine the extent to which t...

    Authors: Ignacio Torres, Dixie Huntley, Mar Tormo, Marisa Calabuig, Juan Carlos Hernández-Boluda, María José Terol, Carlos Carretero, Paula de Michelena, Ariadna Pérez, José Luis Piñana, Javier Colomina, Carlos Solano and David Navarro
    Citation: BMC Infectious Diseases 2022 22:172
    Content type: Research article Published on:

  22. Indoor residual spraying (IRS) is a major method of malaria vector control across sub-Saharan Africa. Effective control is being undermined by the rapid spread of insecticide resistance. There is major investm...

    Authors: Patrick K. Tungu, Mark W. Rowland, Louisa A. Messenger, Graham J. Small, John Bradley, Janneke Snetselaar, Matthew J. Kirby and Njelembo J. Mbewe
    Citation: BMC Infectious Diseases 2022 22:171
    Content type: Study protocol Published on:

  23. Pasteurella multocida is a well-known gram-negative facultative anaerobe well known for its ability to cause soft tissue infections following animal bite or scratch. Here we present a case with mycotic aneurysm ...

    Authors: Jamie Hanson, Ali Etemady-Deylamy, Jared Frisby, Justin D’Addario, Matthew Smeds, Robin Chamberland, Huazhang Guo and Getahun Abate
    Citation: BMC Infectious Diseases 2022 22:170
    Content type: Case report Published on:

  24. Mycoplasma hominis is typically associated with a urogenital tract infection, while its association with bacteremia and pneumonia is rare and therefore easily overlooked. Here we report a M. hominis bloodstream ...

    Authors: Qiang Wang, Xiaofang Tang and Stijn van der Veen
    Citation: BMC Infectious Diseases 2022 22:169
    Content type: Case report Published on:

  25. Necrotizing soft-tissue infections are infections with high mortality. The use of immunoglobulins within a combination therapy including broad-spectrum antibiotics has been debated. We assessed potential benef...

    Authors: Daniel A. Hofmaenner, Pedro David Wendel Garcia, Manuel R. Blum, Sascha David, Reto A. Schuepbach, Philipp K. Buehler, Pascal M. Frey, Annelies S. Zinkernagel and Silvio D. Brugger
    Citation: BMC Infectious Diseases 2022 22:168
    Content type: Research article Published on:

  26. Hepatitis C virus (HCV) has been mainly transmitted through injection drug use, but recently, sexual transmission among men who have sex with men (MSM), which is also a major route of HIV transmission, is incr...

    Authors: Kazuhiko Ikeuchi, Kazuya Okushin, Makoto Saito, Eisuke Adachi, Takeya Tsutsumi, Tomoyuki Takura and Hiroshi Yotsuyanagi
    Citation: BMC Infectious Diseases 2022 22:167
    Content type: Research Published on:

  27. Many studies have reported high efficacy and safety of artesunate-amodiaquine (AS-AQ) and artemether-lumefantrine (AL) when administered under direct observation in Cameroon. There is paucity of data to support t...

    Authors: Peter Thelma Ngwa Niba, Akindeh Mbuh Nji, Innocent Mbulli Ali, Lawrence Fonyonga Akam, Cedric Hermann Dongmo, Jean Paul Kengne Chedjou, Calvino Tah Fomboh, William Dorian Nana, Ornella Laetitia Ayem Oben, Abdel Aziz Selly-Ngaloumo, Marcel N. Moyeh, Jude Achidi Ngu, Ambassa Jean Ludovic, Pierre Martiniel Aboh, Marie Carine Enyegue Ambani, Pierrette Albertine Mbarga Omgba…
    Citation: BMC Infectious Diseases 2022 22:166
    Content type: Research article Published on:

  28. Patients with a severe COVID-19 infection often require admission at an intensive care unit (ICU) when they develop acute respiratory distress syndrome (ARDS). Hyperinflammation plays an important role in the ...

    Authors: Kirby Tong-Minh, Yuri van der Does, Susanna Engelen, Evelien de Jong, Christian Ramakers, Diederik Gommers, Eric van Gorp and Henrik Endeman
    Citation: BMC Infectious Diseases 2022 22:165
    Content type: Research article Published on:

  29. Infectious mononucleosis, a common disease in children and young adults, is often accompanied by elevated transaminase levels and rarely, liver failure. This study aimed to determine whether adenosine deaminas...

    Authors: Ting Shi, Jungen Li, Yuzhu Miao, Linlin Huang and Jianmei Tian
    Citation: BMC Infectious Diseases 2022 22:164
    Content type: Research article Published on:

  30. Coronavirus disease 2019 (COVID-19) has been a major public health importance and its specimen needs to be handled safely due to concerns of potential transmissibility to health care workers. Heat inactivation...

    Authors: Belete Woldesemayat, Gebremedihin Gebremicael, Kidist Zealiyas, Amelework Yilma, Sisay Adane, Mengistu Yimer, Gadissa Gutema, Altaye Feleke and Kassu Desta
    Citation: BMC Infectious Diseases 2022 22:163
    Content type: Research article Published on:

  31. The duration of virus shedding is necessary for determining the infectious period. But there were few quantitative studies on the changes of viral load and the law of the viral shedding in hand foot and mouth ...

    Authors: Xiaoxia Duan, Chaoyong Zhang, Zhenhua Chen, Juan Liao, Yilan Zeng, Weiwei Huang, Xueling Ren, Xueqin Tang, Hongxia Peng, Delan Zhang, Xiao Wang, Ping Yuan and Lu Long
    Citation: BMC Infectious Diseases 2022 22:162
    Content type: Study protocol Published on:

  32. In response to the continuing threat of importing novel coronavirus disease (COVID-19), many countries have implemented some form of border restriction. A repercussion of these restrictions has been that some ...

    Authors: Pippa McDermid, Adam Craig, Meru Sheel and Holly Seale
    Citation: BMC Infectious Diseases 2022 22:161
    Content type: Research Published on:

  33. This study aimed to compare the diagnostic value of the single or combined applications of transient elastography (TE) and multivariate indicators with biopsy for the detection of liver fibrosis in children ca...

    Authors: Haiyan Luo, Songxu Peng, Wenxian Ouyang, Yanfang Tan, Tao Jiang, Lian Tang, Shuangjie Li, Jun Qiu and Changci Zhou
    Citation: BMC Infectious Diseases 2022 22:160
    Content type: Research Published on:

  34. The short-term 0–1–2-month hepatitis B virus (HBV) vaccination schedule was previously implemented in the adult population; however, its long-term immune effect remains unclear. The present study aimed to inve...

    Authors: Juan Wang, Chang-Hai Liu, Yuanji Ma, Xia Zhu, Liru Luo, Yulin Ji and Hong Tang
    Citation: BMC Infectious Diseases 2022 22:159
    Content type: Research Published on:

  35. Current TB diagnostic methods available have been developed for adults and development efforts have neglected the differences in disease and sampling that occur between adults and children. Diagnostic challeng...

    Authors: Xinxin Yang, Matthew F. Wipperman, Sharon Nachman and Nicole S. Sampson
    Citation: BMC Infectious Diseases 2022 22:158
    Content type: Research Published on:

  36. Reliable high-throughput serological assays for SARS-CoV-2 antibodies present an important role in the strength and duration of immunity after vaccination. The study investigated the analytical and clinical pe...

    Authors: Min Li, Ruiwei Jiang, Enyun Wang, Dan Xiong, Tong Ou, Xiuming Zhang and Xiaowen Dou
    Citation: BMC Infectious Diseases 2022 22:157
    Content type: Research Published on:

  37. Healthcare-associated infections are a major threat to patient safety, particularly vulnerable elderly living in nursing homes, who have an increased risk of infections and mortality. Although good hand hygien...

    Authors: Ida Hellum Sandbekken, Åsmund Hermansen, Inger Utne, Ellen Karine Grov and Borghild Løyland
    Citation: BMC Infectious Diseases 2022 22:156
    Content type: Research Published on:

  38. In the absence of an adequate prevention strategy, up to 20% of CMV IgG+ liver transplant recipients (LTR) will develop CMV disease. Despite improved reporting in CMV-DNAemia, there is no consensus as to what ...

    Authors: Oscar A. Fernández-García, Ignacio García-Juárez, Pablo Francisco Belaunzarán-Zamudio, Mario Vilatoba, Andrea Wisniowski-Yáñez, Jacobo Salomón-Ávila, Miriam Bobadilla-del-Valle, José Sifuentes-Osornio and Jennifer M. Cuellar-Rodríguez
    Citation: BMC Infectious Diseases 2022 22:155
    Content type: Research Published on:

  39. Invasive mucormycosis (IM) is a rare and often life-threatening fungal infection, for which clinical and epidemiological understanding is lacking. Electronic health record (EHR) data can be utilized to elucida...

    Authors: Yayue Zhang, Anita H. Sung, Emily Rubinstein, Michael Benigno, Richard Chambers, Nataly Patino and Jalal A. Aram
    Citation: BMC Infectious Diseases 2022 22:154
    Content type: Research article Published on:

  40. COVID-19 vaccine has been available in China since the beginning of the 2021, however, certain numbers of people are reluctant for some reasons to vaccinate. The high vaccine coverage is crucial for controllin...

    Authors: Yiman Huang, Xiaoyou Su, Weijun Xiao, Hao Wang, Mingyu Si, Wenjun Wang, Xiaofen Gu, Li Ma, Li Li, Shaokai Zhang, Chunxia Yang, Yanqin Yu and Youlin Qiao
    Citation: BMC Infectious Diseases 2022 22:153
    Content type: Research article Published on:

  41. Many studies support the protective effect of breastfeeding on respiratory tract infections. Although infant formulas have been developed to provide adequate nutritional solutions, many components in human mil...

    Authors: Arthur H. van Stigt, Katrien Oude Rengerink, Kitty W. M. Bloemenkamp, Wouter de Waal, Sabine M. P. J. Prevaes, Thuy-My Le, Femke van Wijk, Maaike Nederend, Anneke H. Hellinga, Christianne S. Lammers, Gerco den Hartog, Martijn J. C. van Herwijnen, Johan Garssen, Léon M. J. Knippels, Lilly M. Verhagen, Caroline G. M. de Theije…
    Citation: BMC Infectious Diseases 2022 22:152
    Content type: Study protocol Published on:

  42. Drug users are regarded as a high-risk population for HIV infection. Non-occupational post-exposure prophylaxis (nPEP) is internationally regarded as an effective biomedical prevention against HIV but still a ...

    Authors: Kedi Jiao, Haochu Li, Dapeng Zhang, Zhenxia Jiang, Yuxi Lin, Xueyuan Liu, Hengmin Xu, Xuemei Yan, Haoqing Tang and Wei Ma
    Citation: BMC Infectious Diseases 2022 22:151
    Content type: Research article Published on:

  43. Invasive candidal infection combined with bacterial bloodstream infection is one of the common nosocomial infections that is also the main cause of morbidity and mortality. The incidence of invasive Candidal i...

    Authors: Yaling Li, Yutong Wu, Yali Gao, Xueli Niu, Jingyi Li, Mingsui Tang, Chang Fu, Ruiqun Qi, Bing Song, Hongduo Chen, Xinghua Gao, Ying Yang and Xiuhao Guan
    Citation: BMC Infectious Diseases 2022 22:150
    Content type: Research Published on:

  44. COVID-19 is a multi-system infection with emerging evidence-based antiviral and anti-inflammatory therapies to improve disease prognosis. However, a subset of patients with COVID-19 signs and symptoms have rep...

    Authors: Heta Parmar, Margaret Montovano, Padmapriya Banada, Sri Ram Pentakota, Stephanie Shiau, Zhongjie Ma, Kaheerman Saibire, Abby Chopoorian, Michael O’Shaughnessy, Mitchell Hirsch, Priyanshi Jain, Gaiane Demirdjian, Magali Karagueuzian, Thomas Robin, Michael Salvati, Bhavana Patel…
    Citation: BMC Infectious Diseases 2022 22:149
    Content type: Research Published on:

  45. Invasive meningococcal disease (IMD) is a rare but severe bacterial infection, of which a high proportion of survivors are affected by sequelae. In Denmark, IMD is a notifiable disease and data collection on s...

    Authors: Sidsel Skou Voss, Jens Nielsen and Palle Valentiner-Branth
    Citation: BMC Infectious Diseases 2022 22:148
    Content type: Research Published on:

  47. A wealth of scientific evidence supports the effectiveness of HIV prophylaxis and treatment. Homelessness is strongly associated with the health status and viral suppression among underserved populations and c...

    Authors: Vladimir Berthaud, Livette Johnson, Ronda Jennings, Maxine Chandler-Auguste, Abosede Osijo, Marie T. Baldwin, Patricia Matthews-Juarez, Paul Juarez, Derek Wilus and Mohammad Tabatabai
    Citation: BMC Infectious Diseases 2022 22:144
    Content type: Research article Published on:

  48. Intramedullary abscesses are rare infections of the spinal cord. Intramedullary abscesses often have a complex presentation, making a high index of suspicion essential for prompt diagnosis and management.

    Authors: Christian D. Cerecedo-Lopez, Joshua D. Bernstock, Adam A. Dmytriw, Jason A. Chen, Joshua I. Chalif, Saksham Gupta, Joseph Driver, Kevin Huang, Susan E. Stanley, Jonathan Z. Li, John Chi and Yi Lu
    Citation: BMC Infectious Diseases 2022 22:141
    Content type: Case report Published on:

  49. Hospital settings are at increased risk of spreading Coronavirus Disease 2019 (COVID-19) infections, hence non-pharmaceutical prevention interventions (NPPIs) and prioritized vaccination of healthcare workers ...

    Authors: Nobubelo K. Ngandu, Tshiamo M. Mmotsa, Reshmi Dassaye, Alice Thabetha, Willem Odendaal, Natasha Langdown and Duduzile Ndwandwe
    Citation: BMC Infectious Diseases 2022 22:140
    Content type: Research Published on:

  50. Individuals with intellectual and developmental disabilities (IDD) living in congregated settings have increased risk of COVID-19 infection and mortality. Little is known about variant B.1.1.519 with spike mut...

    Authors: Koen M. F. Gorgels, Jozef Dingemans, Brian M. J. W. van der Veer, Volker Hackert, Audrey Y. J. Hensels, Casper D. J. den Heijer, Lieke B. van Alphen, Paul H. M. Savelkoul and Christian J. P. A. Hoebe
    Citation: BMC Infectious Diseases 2022 22:139
    Content type: Research Published on:

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