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  1. Acute otitis media (AOM) is a leading cause of office visits and antibiotic prescriptions in children. Pneumococcal conjugate vaccines were introduced in the USA in 2000 (7-valent, PCV7) and 2010 (13-valent, P...

    Authors: Tianyan Hu, Nicolae Done, Tanaz Petigara, Salini Mohanty, Yan Song, Qing Liu, Esteban Lemus-Wirtz, James Signorovitch, Eric Sarpong and Thomas Weiss
    Citation: BMC Infectious Diseases 2022 22:294
    Content type: Research Published on:

  2. There is a little evidence about the infectiousness of recovered COVID-19 patients. Considering that the circumstance of the isolation of the COVID-19 patients after-discharge is not always optimal, it is not ...

    Authors: Ayat Ahmadi, Amirhossein Poopak, Sina Nazemi, Negin Mohammadi, Bita Eslami, Monireh Sadat Seyyedsalehi, Leila Doshmangir, Seyyed Farshad Allameh and Kazem Zendehdel
    Citation: BMC Infectious Diseases 2022 22:293
    Content type: Research Published on:

  3. Invasive fungal disease (IFD) is a severe complication after haploidentical stem cell transplantation (haplo-HSCT) and has a poor prognosis. It has been shown that genetic polymorphism may be one possible reas...

    Authors: Chen Zhao, Xiao-Su Zhao, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang and Yu-Qian Sun
    Citation: BMC Infectious Diseases 2022 22:292
    Content type: Research Published on:

  4. The aim of our study was to assess the impact the impact of gender and age on reactogenicity to three COVID-19 vaccine products: Biontech/Pfizer (BNT162b2), Moderna (mRNA-1273) and AstraZeneca (ChAdOx). Additi...

    Authors: Irit Nachtigall, Marzia Bonsignore, Sven Hohenstein, Andreas Bollmann, Rosita Günther, Cathrin Kodde, Martin Englisch, Parviz Ahmad-Nejad, Alexander Schröder, Corinna Glenz, Ralf Kuhlen, Petra Thürmann and Andreas Meier-Hellmann
    Citation: BMC Infectious Diseases 2022 22:291
    Content type: Research Published on:

  5. Corynebacterium striatum is a gram-positive facultative anaerobe found in the environment and human flora that has historically been considered a contaminant. More recently, Corynebacterium striatum has been impl...

    Authors: Amber C. Streifel, Cara D. Varley, YoungYoon Ham, Monica K. Sikka and James S. Lewis II
    Citation: BMC Infectious Diseases 2022 22:290
    Content type: Case report Published on:

  6. The prevention of peripherally inserted central catheters (PICC)-associated BSI and central venous catheters (CVC)-associated BSI have been a topic of national importance in China. Therefore, we aimed to explo...

    Authors: Yu Lv, Xiaobo Huang, Yunping Lan, Qi Xia, Fuli Chen, Jiayu Wu, Wei Li, Hongrong Cao, Caixia Xie, Luting Li, Hukui Han, Hui Wang and Qian Xiang
    Citation: BMC Infectious Diseases 2022 22:289
    Content type: Research article Published on:

  7. Vibrio cholerae is a water-borne pathogen with a global burden estimate at 1.4 to 4.0 million annual cases. Over 94% of these cases are reported in Africa and more research is needed to understand cholera dynamic...

    Authors: Gina E. C. Charnley, Ilan Kelman, Katy A. M. Gaythorpe and Kris A. Murray
    Citation: BMC Infectious Diseases 2022 22:288
    Content type: Database Published on:

  8. Biomarkers, such as leukocyte count, C-reactive protein (CRP), and procalcitonin (PCT), have been commonly used to predict the occurrence of life-threatening bacteremia and provide prognostic information, give...

    Authors: Frank Lien, Huang-Shen Lin, You-Ting Wu and Tzong-Shi Chiueh
    Citation: BMC Infectious Diseases 2022 22:287
    Content type: Research article Published on:

  9. Azithromycin is a broad-spectrum antibiotic that has moderate antimalarial activity and has been shown to reduce all-cause mortality when biannually administered to children under five in high mortality settin...

    Authors: Jessica Brogdon, Clarisse Dah, Ali Sié, Mamadou Bountogo, Boubacar Coulibaly, Idrissa Kouanda, Mamadou Ouattara, Guillaume Compaoré, Eric Nebie, Mariam Seynou, Elodie Lebas, Fanice Nyatigo, Huiyu Hu, Benjamin F. Arnold, Thomas M. Lietman and Catherine E. Oldenburg
    Citation: BMC Infectious Diseases 2022 22:285
    Content type: Research Published on:

  10. There is an urgent need to expand testing for SARS-CoV-2 and other respiratory pathogens as the global community struggles to control the COVID-19 pandemic. Current diagnostic methods can be affected by supply...

    Authors: Orchid M. Allicock, Mary E. Petrone, Devyn Yolda-Carr, Mallery Breban, Hannah Walsh, Anne E. Watkins, Jessica E. Rothman, Shelli F. Farhadian, Nathan D. Grubaugh and Anne L. Wyllie
    Citation: BMC Infectious Diseases 2022 22:284
    Content type: Research Published on:

  11. The aim of this study was to analyze the present situation of Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), Mycoplasma genitalium (MG) and Neisseria gonorrhoeae (NG) infections among obstetrics and gyn...

    Authors: Ting Liu, Shu-yu Lai, Wei Zhou, Yan-ling Liu, Sha-sha Chen and Yong-mei Jiang
    Citation: BMC Infectious Diseases 2022 22:283
    Content type: Research Published on:

  12. [18F]FDG-PET/CT is used for diagnosing metastatic infections in Staphylococcus aureus bacteremia (SAB) and guidance of antibiotic treatment. The impact of [18F]FDG-PET/CT on outcomes remains to be determined. The...

    Authors: D. T. P. Buis, E. Sieswerda, I. J. E. Kouijzer, W. Y. Huynh, G. L. Burchell, M. A. H. Berrevoets, J. M. Prins and K. C. E. Sigaloff
    Citation: BMC Infectious Diseases 2022 22:282
    Content type: Research Published on:

  13. The distribution of HIV is not uniform in Ethiopia with some regions recording higher prevalence than others. However, reported regional HIV prevalence estimates mask the heterogeneity of the epidemic within r...

    Authors: Nemso Geda Bedaso and Legesse Kassa Debusho
    Citation: BMC Infectious Diseases 2022 22:281
    Content type: Research Published on:

  14. Deep neck space abscess (DNSA) is a serious infection in the head and neck. Antibiotic therapy is an important treatment in patients with DNSA. However, the results of bacterial culture need at least 48 h, and...

    Authors: Wenxiang Gao, Yu Lin, Huijun Yue, Weixiong Chen, Tianrun Liu, Jin Ye, Qian Cai, Fei Ye, Long He, Xingqiang Xie, Guoping Xiong, Jianhui Wu, Bin Wang, Weiping Wen and Wenbin Lei
    Citation: BMC Infectious Diseases 2022 22:280
    Content type: Research Published on:

  15. Since 2010, the Blood Center of Zhejiang province, China, has conducted a pilot nucleic acid amplification testing (NAT) screening of blood donors for Hepatitis B virus (HBV), Hepatitis C virus (HCV), and Huma...

    Authors: Danxiao Wu, Fangjun Feng, Xiaojuan Wang, Dairong Wang, Yiqin Hu, Yang Yu, Jihong Huang, Min Wang, Jie Dong, Yaling Wu, Hong Zhu and Faming Zhu
    Citation: BMC Infectious Diseases 2022 22:279
    Content type: Research Published on:

  16. Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide, affecting about 80% of women up to the age of 50. The persistent infection of high risk-HPV types (HR-HPV) is the leading...

    Authors: Majid Zare-Bidaki, Mahmoud Zardast, Ali Nadjafi-Semnani, Mohammad Nadjafi-Semnani, Davod Javanmard, Shokouh Ghafari and Nahid Ghanbarzadeh
    Citation: BMC Infectious Diseases 2022 22:278
    Content type: Research Published on:

  17. Although the RECOVERY trial showed that dexamethasone was efficacious for the treatment of coronavirus disease 2019 (COVID-19), its impact on the risk of pulmonary embolism (PE) and other serious procoagulant ...

    Authors: Hidenori Takahashi, Yoshinobu Iwasaki, Takayasu Watanabe, Naoki Ichinose and Toshimi Oda
    Citation: BMC Infectious Diseases 2022 22:277
    Content type: Case report Published on:

  18. SARS-CoV-2 rapid antigen (Ag) detection kits are widely used in addition to quantitative reverse transcription PCR PCR (RT-qPCR), as they are cheaper with a rapid turnaround time. As there are many concerns re...

    Authors: Chandima Jeewandara, Dinuka Guruge, Pradeep Darshana Pushpakumara, Deshan Madhusanka, Tibutius Thanesh Jayadas, Indika Prasad Chaturanga, Inoka Sepali Aberathna, Saubhagya Danasekara, Thilagaraj Pathmanathan, Deshni Jayathilaka, Gayasha Somathilaka, Heshan Kuruppu, Laksiri Gomes, Vitjith Gunasekara, Ruwan Wijayamuni, Graham S. Ogg…
    Citation: BMC Infectious Diseases 2022 22:276
    Content type: Research article Published on:

  19. Mass gatherings can not only trigger major outbreaks on-site but also facilitate global spread of infectious pathogens. Hajj is one of the largest mass gathering events worldwide where over two million pilgrim...

    Authors: Laurent Coudeville, Amine Amiche, Ashrafur Rahman, Julien Arino, Biao Tang, Ombeline Jollivet, Alp Dogu, Edward Thommes and Jianhong Wu
    Citation: BMC Infectious Diseases 2022 22:275
    Content type: Research article Published on:

  20. Motivated by the need for precise epidemic control and epidemic-resilient urban design, this study aims to reveal the joint and interactive associations between urban socioeconomic, density, connectivity, and ...

    Authors: Anshu Zhang, Wenzhong Shi, Chengzhuo Tong, Xiaosheng Zhu, Yijia Liu, Zhewei Liu, Yepeng Yao and Zhicheng Shi
    Citation: BMC Infectious Diseases 2022 22:274
    Content type: Research Published on:

  21. Since the discovery of direct-acting antivirals, treatment for hepatitis C virus (HCV) is increasingly accessible in low-resource settings, but quality of care in these settings is not known. We described prog...

    Authors: Innocent Kamali, Fabienne Shumbusho, Dale A. Barnhart, Françoise Nyirahabihirwe, Jean de la Paix Gakuru, Wellars Dusingizimana, Esdras Nizeyumuremyi, Placide Habinshuti, Stephen Walker, Jean Damascene Makuza, Janvier Serumondo, Gallican Nshogoza Rwibasira and Jean d’Amour Ndahimana
    Citation: BMC Infectious Diseases 2022 22:272
    Content type: Research Published on:

  22. During the COVID-19 outbreak in Taiwan between May 11 and June 20, 2021, the observed fatality rate (FR) was 5.3%, higher than the global average at 2.1%. The high number of reported deaths suggests that many ...

    Authors: Hsiang-Yu Yuan, M. Pear Hossain, Tzai-Hung Wen and Ming-Jiuh Wang
    Citation: BMC Infectious Diseases 2022 22:271
    Content type: Research Published on:

  23. From January to May 2021 the alpha variant (B.1.1.7) of SARS-CoV-2 was the most commonly detected variant in the UK. Following this, the Delta variant (B.1.617.2) then became the predominant variant. The UK CO...

    Authors: Karan Pattni, Daniel Hungerford, Sarah Adams, Iain Buchan, Christopher P. Cheyne, Marta García-Fiñana, Ian Hall, David M. Hughes, Christopher E. Overton, Xingna Zhang and Kieran J. Sharkey
    Citation: BMC Infectious Diseases 2022 22:270
    Content type: Research article Published on:

  24. To investigate the difference in the severity of illness, organ dysfunction, and prognosis of acute cholangitis due to different pathogenic bacterial infection types.

    Authors: Shijing Tian, Kaili Li, Hong Tang, Yan Peng, Liang Xia, Xi Wang, Xiaoying Chen and Fachun Zhou
    Citation: BMC Infectious Diseases 2022 22:269
    Content type: Research Published on:

  25. Existing literature mostly investigated the relationship of acute or short-term glucocorticoid exposure to HIV disease progression using cortisol levels in serum, saliva, or urine. Data are limited on the rela...

    Authors: Quan Zhang, Xiaoming Li, Shan Qiao, Shuaifeng Liu, Yuejiao Zhou and Zhiyong Shen
    Citation: BMC Infectious Diseases 2022 22:268
    Content type: Research Published on:

  26. The association between H. pylori (Helicobacter pylori) infection and gastroesophageal reflux disease (GERD) is a complex and confusing subject. The aim of this study was to evaluate the association between he...

    Authors: Ramin Niknam, Kamran Bagheri Lankarani, Mohsen Moghadami, Seyed Alireza Taghavi, Leila Zahiri and Mohammad Javad Fallahi
    Citation: BMC Infectious Diseases 2022 22:267
    Content type: Research Published on:

  27. Determining the prevalence of pre-treatment HIV drug resistance (PDR) is important to assess the effectiveness of first-line therapies. To determine PDR prevalence in Papua New Guinea (PNG), we conducted a nat...

    Authors: Janet Gare, Ben Toto, Percy Pokeya, Linh-Vi Le, Nick Dala, Namarola Lote, Bangan John, Abel Yamba, Kevin Soli, Joshua DeVos, Heather Paulin, Nick Wagar, Du-Ping Zheng, Takeshi Nishijima, Peniel Boas, Angela Kelly-Hanku…
    Citation: BMC Infectious Diseases 2022 22:266
    Content type: Research Published on:

  28. Postvitrectomy endophthalmitis is a rare and serious complication following vitreoretinal surgeries. Morganella morganii, an emerging gram-negative, facultative anaerobic rod, is related to severe nosocomial infe...

    Authors: Chung-Ting Wang, Yin-Hsi Chang, Kuan-Jen Chen and Hung-Da Chou
    Citation: BMC Infectious Diseases 2022 22:265
    Content type: Case report Published on:

  29. Schistosomiasis and soil transmitted helminths (STH) have been associated with compromised child development. We determined the effect of schistosomiasis and STH on expressive language skills among isiZulu spe...

    Authors: Xolisile I. Mazibuko and Moses Chimbari
    Citation: BMC Infectious Diseases 2022 22:264
    Content type: Research article Published on:

  30. Clonorchiasis is a widespread yet neglected foodborne disease with over 85% of all cases found in China. Guangxi province, located in southeastern China, ranks among the highest endemic provinces. We explore t...

    Authors: Yihong Xie, Kaushi S. T. Kanankege, Zhihua Jiang, Shun Liu, Yichao Yang, Xiaoling Wan and Andres M. Perez
    Citation: BMC Infectious Diseases 2022 22:263
    Content type: Research article Published on:

  31. HIV infections which are diagnosed at advanced stages are associated with significantly poorer health outcomes. In Germany, the proportion of persons living with HIV who are diagnosed at later stages has remai...

    Authors: Annemarie Pantke, Jens Hoebel, Matthias an der Heiden, Niels Michalski, Barbara Gunsenheimer-Bartmeyer, Kirsten Hanke, Norbert Bannert, Viviane Bremer and Uwe Koppe
    Citation: BMC Infectious Diseases 2022 22:258
    Content type: Research Published on:

  33. COVID-19 pandemic has a devastating impact on the economies and health care system of sub-Saharan Africa. Healthcare workers (HWs), the main actors of the health system, are at higher risk because of their occ...

    Authors: Tesfaye Gelanew, Berhanu Seyoum, Andargachew Mulu, Adane Mihret, Markos Abebe, Liya Wassie, Baye Gelaw, Abebe Sorsa, Yared Merid, Yilkal Muchie, Zelalem Teklemariam, Bezalem Tesfaye, Mahlet Osman, Gutema Jebessa, Abay Atinafu, Tsegaye Hailu…
    Citation: BMC Infectious Diseases 2022 22:261
    Content type: Research Published on:

  34. Tuberculosis (TB) control is threatened by an increasing prevalence of diabetes mellitus (DM), particularly in endemic countries. Screening for DM is not routinely implemented in Tanzania; therefore, we aimed ...

    Authors: Kenneth Cleophace Byashalira, Nyasatu Godfrey Chamba, Yosra Alkabab, Peter Masunga Mbelele, Nyanda Elias Ntinginya, Kaushik Laxmidas Ramaiya, Mohamed Zahir Alimohamed, Scott Kirkland Heysell, Blandina Theophil Mmbaga, Ib Christian Bygbjerg, Dirk Lund Christensen, Stellah George Mpagama and Troels Lillebaek
    Citation: BMC Infectious Diseases 2022 22:260
    Content type: Research Published on:

  35. Many studies in hospital settings exist and have shown healthcare employees to be particularly exposed to SARS-CoV-2. While research focused on hospital staff, little evidence exists for employees in nursing h...

    Authors: Erin A. West, Olivia J. Kotoun, Larissa J. Schori, Julia Kopp, Marco Kaufmann, Manuela Rasi, Jan Fehr, Milo A. Puhan and Anja Frei
    Citation: BMC Infectious Diseases 2022 22:259
    Content type: Research article Published on:

  36. A substantial body of evidence has recently emphasized the risks associated with antibiotic resistance (ABR) in conflicts in the Middle East. War-related, and more specifically weapon-related wounds can be an ...

    Authors: Sally Yaacoub, Claudia Truppa, Thomas Ingemann Pedersen, Hicham Abdo and Rodolfo Rossi
    Citation: BMC Infectious Diseases 2022 22:257
    Content type: Research Published on:

  37. Rv3737 is the sole homologue of multifunctional transporter ThrE in Mycobacterium tuberculosis (Mtb). In this study, we aimed to investigate whether this transporter participates in vitro and in vivo survival of

    Authors: Qing Li, Zhangli Peng, Xuefeng Fu, Hong Wang, Zhaoliang Zhao, Yu Pang and Ling Chen
    Citation: BMC Infectious Diseases 2022 22:256
    Content type: Research Published on:

  38. Chlamydia trachomatis (CT) is the most common bacterial sexually transmitted infection (STI) worldwide. CT is mainly asymptomatic. Test-and-treat strategies are widely implemented to prevent transmission and comp...

    Authors: Nicole H. T. M. Dukers-Muijrers, Ymke J. Evers, Christian J. P. A. Hoebe, Petra F. G. Wolffs, Henry J. C. de Vries, Bernice Hoenderboom, Marianne A. B. van der Sande, Janneke Heijne, Jeffrey D. Klausner, Jane S. Hocking and Jan van Bergen
    Citation: BMC Infectious Diseases 2022 22:255
    Content type: Review Published on:

  39. Racial/ethnic minorities are at higher risk for severe COVID-19. This may be related to social determinants that lead to chronic inflammatory states. The aims of the study were to determine if there are racial...

    Authors: Ronaldo C. Go, Themba Nyirenda, Maryam Bojarian, Davood K. Hosseini, Kevin Kim, Mehek Rahim, Elli G. Paleoudis, Anna C. Go, Zhiyong Han, Steven J. Sperber and Anjali Gupta
    Citation: BMC Infectious Diseases 2022 22:254
    Content type: Research Published on:

  40. Human rhinovirus (HRV) is the predominant etiological agent of the common cold in children and adults. A recent study showed that the inhibitory effect of face masks on viral shedding of HRV was less prominent...

    Authors: Ran Jia, Lijuan Lu, Shu Li, Pengcheng Liu, Menghua Xu, Lingfeng Cao, Liyun Su and Jin Xu
    Citation: BMC Infectious Diseases 2022 22:253
    Content type: Research Published on:

  41. For many people public transport is the only mode of travel, and it can be challenging to keep the necessary distances in such a restricted space. The exact role of public transportation and risk of SARS-CoV-2...

    Authors: Merete Ellingjord-Dale, Karl Trygve Kalleberg, Mette S. Istre, Anders B. Nygaard, Sonja H. Brunvoll, Linn M. Eggesbø, John Arne Dahl, Eyrun F. Kjetland, Giske Ursin and Arne Søraas
    Citation: BMC Infectious Diseases 2022 22:252
    Content type: Research Published on:

  42. Forecasting new cases, hospitalizations, and disease-induced deaths is an important part of infectious disease surveillance and helps guide health officials in implementing effective countermeasures. For disea...

    Authors: Nino Antulov-Fantulin and Lucas Böttcher
    Citation: BMC Infectious Diseases 2022 22:251
    Content type: Research article Published on:

  43. This study aims to investigate the association between CD4+ T cell count and combined antiretroviral therapy (cART) with the prevalence of anal human papillomavirus (HPV) infection among HIV-positive male cohort ...

    Authors: Jing Zhang, Xiaoxiao Chen, Yiwen Ye, Weiwei Shen, Xiaohong Ye, Yajun Lin, Zhebin Lin, Shigang Tan, Meiyang Gao, Yingying Ding, Haijiang Lin, Youyi Wang, Na He and Xing Liu
    Citation: BMC Infectious Diseases 2022 22:250
    Content type: Research Published on:

  44. Enteric parasites are endemic in many of the countries from which refugees originate. Clinical guidelines vary in approaches to screening for and treating intestinal parasites in refugee receiving countries. T...

    Authors: Frank Müller, Shivani Chandra, Isaac I. Bogoch, Meb Rashid and Vanessa Redditt
    Citation: BMC Infectious Diseases 2022 22:249
    Content type: Research Published on:

  45. In older adult patients, bloodstream infections cause significant mortality. However, data on long-term prognosis in very elderly patients are scarce. This study aims to assess 1-year mortality from bacteraemi...

    Authors: Rubén Hernández-Quiles, Esperanza Merino-Lucas, Vicente Boix, Adela Fernández-Gil, Juan C. Rodríguez-Díaz, Adelina Gimeno, Beatriz Valero, Rosario Sánchez-Martínez and Jose-Manuel Ramos-Rincón
    Citation: BMC Infectious Diseases 2022 22:248
    Content type: Research Published on:

  46. Colombia has been one of the Latin American countries seriously affected by the covid-19 pandemic. Risk factors for severe disease and death in COVID 19 have been described across the world. Here we report the...

    Authors: Deving Arias Ramos, Diana Lizbeth Restrepo Rueda, Erika Vanessa Rios Quintero, Juan Camilo Olaya Gómez and Isabella Cortés Bonilla
    Citation: BMC Infectious Diseases 2022 22:247
    Content type: Research Published on:

  47. Mycobacterial time to positivity (TTP) in liquid culture media has predictive value for longer term outcomes in pulmonary tuberculosis, but has not been thoroughly studied in nontuberculous mycobacterial pulmo...

    Authors: Christina M. Mingora, Bryan A. Garcia, Kevin C. Mange, Dayton W. Yuen, Monika Ciesielska, Jakko van Ingen, Patrick A. Flume and Susan E. Dorman
    Citation: BMC Infectious Diseases 2022 22:246
    Content type: Research Published on:

  48. Effective treatment options for recurrent Clostridioides difficile infection (rCDI) are limited, with high recurrence rates associated with the current standard of care. Herein we report results from an open-labe...

    Authors: Robert Orenstein, Erik R. Dubberke, Sahil Khanna, Christine H. Lee, David Yoho, Stuart Johnson, Gail Hecht, Herbert L. DuPont, Dale N. Gerding, Ken F. Blount, Sarah Mische and Adam Harvey
    Citation: BMC Infectious Diseases 2022 22:245
    Content type: Research Published on:

  50. The unique characteristics of psychiatric institutions contribute to the onset and spread of infectious agents. Infection prevention and control (IPC) is essential to minimise transmission and manage outbreaks...

    Authors: Famke Houben, Mitch van Hensbergen, Casper D. J. den Heijer, Nicole H. T. M. Dukers-Muijrers and Christian J. P. A. Hoebe
    Citation: BMC Infectious Diseases 2022 22:243
    Content type: Research Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2022 22:394

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