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  1. The conjugate vaccine against serogroup A Neisseria meningitidis (NmA), MenAfriVac, is currently being introduced throughout the African meningitis belt. In repeated multicentre cross-sectional studies in Burkina...

    Authors: Paul A Kristiansen, Absatou Ky Ba, Abdoul-Salam Ouédraogo, Idrissa Sanou, Rasmata Ouédraogo, Lassana Sangaré, Fabien Diomandé, Denis Kandolo, Inger Marie Saga, Lara Misegades, Thomas A Clark, Marie-Pierre Préziosi and Dominique A Caugant
    Citation: BMC Infectious Diseases 2014 14:663
    Content type: Research article Published on:

  2. Healthcare providers (HCPs) play a critical role in controlling the spread of sexually transmitted infections (STI) through early and accurate diagnosis, appropriate treatment and prevention counselling. This ...

    Authors: Pham Thi Lan, Ho Dang Phuc, Nguyen Quynh Hoa, Nguyen Thi Kim Chuc and Cecilia Stålsby Lundborg
    Citation: BMC Infectious Diseases 2014 14:646
    Content type: Research article Published on:

  3. Little is known about the parasite/host factors that lead to Post Kala-azar Dermal Leishmaniasis (PKDL) in some visceral leishmaniasis (VL) patients after drug-cure. Studies in Sudan provide evidence for assoc...

    Authors: Mohamed A M Salih, Michaela Fakiola, Mohamed H Abdelraheem, Brima M Younis, Ahmed M Musa, Ahmed M ElHassan, Jenefer M Blackwell, Muntaser E Ibrahim and Hiba S Mohamed
    Citation: BMC Infectious Diseases 2014 14:662
    Content type: Research article Published on:

  4. There is an urgent need for improved vaccines to protect against tuberculosis. The currently available vaccine Bacille Calmette-Guerin (BCG) has varying immunogenicity and efficacy across different populations...

    Authors: Rachel Tanner, Kristina Kakalacheva, Ellen Miller, Ansar A Pathan, Rod Chalk, Clare R Sander, Tom Scriba, Michelle Tameris, Tony Hawkridge, Hassan Mahomed, Greg Hussey, Willem Hanekom, Anna Checkley, Helen McShane and Helen A Fletcher
    Citation: BMC Infectious Diseases 2014 14:660
    Content type: Research article Published on:

  5. In order to investigate the epidemiology, molecular characteristics, and distribution of extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli from community-onset infections in Chinese county...

    Authors: Jing Zhang, Beiwen Zheng, Lina Zhao, Zeqing Wei, Jinru Ji, Lanjuan Li and Yonghong Xiao
    Citation: BMC Infectious Diseases 2014 14:659
    Content type: Research article Published on:

  6. Rising rates of infectious diseases in international migrants has reignited the debate around screening. There have been calls to strengthen primary-care-based programmes, focusing on latent TB. We did a cross...

    Authors: Sally Hargreaves, Farah Seedat, Josip Car, Rod Escombe, Samia Hasan, Joseph Eliahoo and Jon S Friedland
    Citation: BMC Infectious Diseases 2014 14:657
    Content type: Research article Published on:

  7. QuantiFERON-TB Gold In-Tube® (QFT-GIT) test is used for the diagnosis of latent tuberculosis (TB) infection. Besides, QFT-GIT test could allow tracking changes in immune response among TB patients and their co...

    Authors: Mulugeta Belay, Mengistu Legesse, Daniel Dagne, Adane Mihret, Yonas Bekele, Girmay Medhin, Gunnar Bjune and Fekadu Abebe
    Citation: BMC Infectious Diseases 2014 14:654
    Content type: Research article Published on:

  8. Majority of individuals with history of visceral leishmaniasis (VL) exhibit strong immunity to re-infection, however, the mechanism of resistance is poorly understood. It is unclear whether CD8+ T cells contribut...

    Authors: Himanshu Kaushal, Rachel Bras-Gonçalves, Narender Singh Negi, Jean-Loup Lemesre, Gérard Papierok and Poonam Salotra
    Citation: BMC Infectious Diseases 2014 14:653
    Content type: Research article Published on:

  9. Listeria monocytogenes causes gastroenteritis, meningitis and bacteraemia in immunocompromised, pregnant patients, the elderly as well in immunocompetent patients. Focal infections with this organism are uncommo...

    Authors: Ruchir Chavada, Caitlin Keighley, Syed Quadri, Ray Asghari, Ann Hofmeyr and Hong Foo
    Citation: BMC Infectious Diseases 2014 14:641
    Content type: Case report Published on:

  10. Intrahepatic hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is the original template for HBV replication. The persistence of cccDNA is responsible for the recurrence of HBV infection. The dete...

    Authors: Yanwei Zhong, Shuangye Hu, Chen Xu, Yulai Zhao, Dongping Xu, Yanqing Zhao, Jingmin Zhao, Zhibin Li, Xiuchang Zhang, Hongfei Zhang and Jin Li
    Citation: BMC Infectious Diseases 2014 14:608
    Content type: Research article Published on:

  11. The innate immune system recognizes pathogens via its pattern recognition receptors. The objective of this study was to investigate the role of the nucleotide-binding oligomerization domain (NOD) proteins, a f...

    Authors: Xinjie Liu, Qizheng Han and Junhong Leng
    Citation: BMC Infectious Diseases 2014 14:648
    Content type: Research article Published on:

  12. Recreational drug use (RDU) may result in sexual disinhibition and higher risk for HIV and other sexually transmitted infections (STIs) among men who have sex with men (MSM) in China. We assessed whether RDU w...

    Authors: Jun-Jie Xu, Chen Zhang, Qing-Hai Hu, Zhen-Xing Chu, Jing Zhang, Yong-Ze Li, Lin Lu, Zhe Wang, Ji-Hua Fu, Xi Chen, Hong-Jing Yan, Ming-Hua Zhuang, Yong-Jun Jiang, Wen-Qing Geng, Sten H Vermund, Hong Shang…
    Citation: BMC Infectious Diseases 2014 14:642
    Content type: Research article Published on:

  13. While cultivation of pathogens represents a foundational diagnostic approach in the study of infectious diseases, its value for the confirmation of clinical diagnosis of Buruli ulcer is limited by the fact tha...

    Authors: Martin W Bratschi, Miriam Bolz, Leticia Grize, Sarah Kerber, Jacques C Minyem, Alphonse Um Boock, Dorothy Yeboah-Manu, Marie-Thérèse Ruf and Gerd Pluschke
    Citation: BMC Infectious Diseases 2014 14:636
    Content type: Research article Published on:

  14. Patients in pediatric intensive care Units (PICU) are susceptible to infections with antibiotic resistant organisms which increase the morbidity, mortality and cost of care.

    Authors: Naveed-ur-Rehman Siddiqui, Farah Naz Qamar, Humaira Jurair and Anwarul Haque
    Citation: BMC Infectious Diseases 2014 14:626
    Content type: Research article Published on:

  17. Bloodstream infections (BSIs) are frequent in ICU and is a prognostic factor of severe sepsis. Community acquired BSIs usually due to susceptible bacteria should be clearly differentiated from healthcare assoc...

    Authors: Jean-François Timsit, Jean-François Soubirou, Guillaume Voiriot, Sarah Chemam, Mathilde Neuville, Bruno Mourvillier, Romain Sonneville, Eric Mariotte, Lila Bouadma and Michel Wolff
    Citation: BMC Infectious Diseases 2014 14:489
    Content type: Review Published on:

  19. Patients with severe viral infections are often hospitalized in intensive care units (ICUs) and recent studies underline the frequency of viral detection in ICU patients. Viral infections in the ICU often invo...

    Authors: Theodoros Kelesidis, Ioannis Mastoris, Aliki Metsini and Sotirios Tsiodras
    Citation: BMC Infectious Diseases 2014 14:321
    Content type: Review Published on:

  20. High mortality and morbidity rates associated with severe infections in the critically ill continue to be a significant issue for the healthcare system. In view of the diverse and unique pharmacokinetic profil...

    Authors: Gloria Wong, Fekade Bruck Sime, Jeffrey Lipman and Jason A Roberts
    Citation: BMC Infectious Diseases 2014 14:288
    Content type: Review Published on:

  21. The management of infections in surgical intensive care unit patients poses specific challenges. Although the overall approach to the patient is no different from other patients, diagnosis is often problematic...

    Authors: Jan De Waele and Liesbet De Bus
    Citation: BMC Infectious Diseases 2014 14:193
    Content type: Review Published on:

  22. The increasing occurrence of multidrug resistant (MDR) bacteria arises at a time when there is a lack of antibiotics active against these pathogens and few new antimicrobials are in the pipelines of the pharma...

    Authors: José Garnacho-Montero, Yael Corcia-Palomo, Rosario Amaya-Villar and Luis Martin-Villen
    Citation: BMC Infectious Diseases 2014 14:135
    Content type: Review Published on:

  23. Microaspiration of subglottic secretions through channels formed by folds in high volume-low pressure poly-vinyl chloride cuffs of endotracheal tubes is considered a significant pathogenic mechanism of ventila...

    Authors: Stijn I Blot, Jan Poelaert and Marin Kollef
    Citation: BMC Infectious Diseases 2014 14:119
    Content type: Review Published on:

  24. Gram-positive bacteria to include methicillin-resistant Staphylococcus aureus (MRSA), methicillin-susceptible Staphylococcus aureus (MSSA), and enterococci, to include vancomycin-resistant enterococci (VRE), disp...

    Authors: Cristina Vazquez-Guillamet and Marin H Kollef
    Citation: BMC Infectious Diseases 2014 14:92
    Content type: Review Published on:

  25. Nitroxoline, a hydroxychinoline derivate, has been used for many years to treat urinary tract infections (UTI). Many uncontrolled, but only few controlled clinical studies have been published. Four so far unpu...

    Authors: Kurt G Naber, Hiltrud Niggemann, Gisela Stein and Guenter Stein
    Citation: BMC Infectious Diseases 2014 14:628
    Content type: Research article Published on:

  26. Evolving gonococcal antimicrobial resistance (AMR) poses a serious threat to public health. The aim of this study was to: update antimicrobial susceptibility data of Neisseria gonorrhoeae recently isolated in Nan...

    Authors: Sai Li, Xiao-Hong Su, Wen-Jing Le, Fa-Xing Jiang, Bao-Xi Wang and Peter A Rice
    Citation: BMC Infectious Diseases 2014 14:622
    Content type: Research article Published on:

  27. Acute febrile illness is common among those seeking medical care and is frequently treated empirically with the underlying illness remaining undiagnosed in resource-poor countries. A febrile illness study was ...

    Authors: Wiriya Rutvisuttinunt, Piyawan Chinnawirotpisan, Chonticha Klungthong, Sanjaya Kumar Shrestha, Amod Bahadur Thapa, Arjun Pant, Samuel L Yingst, In-Kyu Yoon, Stefan Fernandez and Julie A Pavlin
    Citation: BMC Infectious Diseases 2014 14:606
    Content type: Research article Published on:

  28. Leishmania infantum is a flagellated protozoan parasite that is able to parasitize blood and tissue. Leishmania species cause a spectrum of clinical disease with cutaneous, visceral or mucosal involvement. L. in...

    Authors: Amy Crowe, John Slavin, Damien Stark and Craig Aboltins
    Citation: BMC Infectious Diseases 2014 14:597
    Content type: Case report Published on:

  29. Prosthetic joint infection (PJI) due to Salmonella is rare. Numerous outbreaks of Salmonella have been reported throughout the United States in the last decade. We reviewed and analyzed cases of Salmonella PJI se...

    Authors: Arjun Gupta, Elie F Berbari, Douglas R Osmon and Abinash Virk
    Citation: BMC Infectious Diseases 2014 14:633
    Content type: Research article Published on:

  30. Viral central nervous system (CNS) infections are common in countries where malaria is endemic but, due to limited laboratory facilities, few studies have systematically examined the prevalence and clinical co...

    Authors: Moses Laman, Ilomo Hwaiwhanje, Cathy Bona, Jonathan Warrel, Susan Aipit, David Smith, Joanna Noronha, Peter Siba, Ivo Mueller, Inoni Betuela, Timothy ME Davis and Laurens Manning
    Citation: BMC Infectious Diseases 2014 14:630
    Content type: Research article Published on:

  31. Clostridium difficile infection (CDI) remains a major health problem worldwide. Antibiotic use, in general, and clindamycin and ciprofloxacin, in particular, have been implicated in the pathogenesis of CDI. Here...

    Authors: Andrea C Büchler, Silvana K Rampini, Simon Stelling, Bruno Ledergerber, Silke Peter, Alexander Schweiger, Christian Ruef, Reinhard Zbinden and Roberto F Speck
    Citation: BMC Infectious Diseases 2014 14:607
    Content type: Research article Published on:

  32. Acute Aspergillus fumigatus infection in immunocompetent patients is rare. This is the first known case of a patient who survived Aspergillus sepsis after being treated early with veno-venous extracorporeal membr...

    Authors: Nina Jung, Silke Mronga, Susanne Schroth, Timon Vassiliou, Frank Sommer, Eduard Walthers, Christian Aepinus, Andreas Jerrentrup, Claus Vogelmeier, Angelique Holland and Rembert Koczulla
    Citation: BMC Infectious Diseases 2014 14:600
    Content type: Case report Published on:

  33. From 2007 to 2010, (the southern part of) the Netherlands experienced a large Q fever epidemic, with more than 4,000 reported symptomatic cases. Approximately 1 - 5% of the acute Q fever patients develop chron...

    Authors: Rana Jajou, Cornelia Christina Henrica Wielders, Monique Leclercq, Jeroen van Leuken, Shahan Shamelian, Nicole Renders, Wim van der Hoek and Peter Schneeberger
    Citation: BMC Infectious Diseases 2014 14:629
    Content type: Research article Published on:

  34. Early diagnosis and prompt effective therapy are crucial for the prevention of tuberculosis (TB) transmission, particularly in regions with high levels of multi-drug resistant TB. This study aimed to evaluate ...

    Authors: Tatiana V Belkina, Doniyor S Khojiev, Mirzagaleb N Tillyashaykhov, Zinaida N Tigay, Marat U Kudenov, Jurjen Duintjer Tebbens and Jiri Vlcek
    Citation: BMC Infectious Diseases 2014 14:624
    Content type: Research article Published on:

  35. Clinical differentiation of influenza from dengue and other febrile illnesses (OFI) is difficult, and available rapid diagnostic tests have limited sensitivity.

    Authors: Shi-Yu Huang, Ing-Kit Lee, Lin Wang, Jien-Wei Liu, Shih-Chiang Hung, Chien-Chih Chen, Tzu-Yao Chang and Wen-Chi Huang
    Citation: BMC Infectious Diseases 2014 14:623
    Content type: Research article Published on:

  36. The protozoan parasite Entamoeba histolytica (E. histolytica) usually asymptomatically colonizes the human intestine. In the minority of the cases, the parasite evades from the gut and can induce severe symptoms ...

    Authors: Hannah Bernin, Claudia Marggraff, Thomas Jacobs, Norbert Brattig, Le Van An, Jörg Blessmann and Hannelore Lotter
    Citation: BMC Infectious Diseases 2014 14:621
    Content type: Research article Published on:

  37. A previously published proof of principle phase IIa trial with 113 patients from Kabul showed that bipolar high-frequency (HF) electro-cauterization (EC) of cutaneous leishmaniasis (CL) ulcers and subsequent m...

    Authors: Hans-Christian Stahl, Faridullah Ahmadi, Ulrike Schleicher, Rainer Sauerborn, Justo Lorenzo Bermejo, Mohammed Latif Amirih, Ibrahim Sakhayee, Christian Bogdan and Kurt-Wilhelm Stahl
    Citation: BMC Infectious Diseases 2014 14:619
    Content type: Research article Published on:

  39. The widespread use of empiric broad spectrum antibiotics has contributed to the global increase of Resistant Gram-Negative Bacilli (RGNB) infections in intensive care units (ICU). The aim of this study was to ...

    Authors: Anupama Vasudevan, Amartya Mukhopadhyay, Jialiang Li, Eugene Goh Yu Yuen and Paul Ananth Tambyah
    Citation: BMC Infectious Diseases 2014 14:615
    Content type: Research article Published on:

  40. Dengue fever, a mosquito-borne viral disease, is a rapidly emerging public health problem in Ecuador and throughout the tropics. However, we have a limited understanding of the disease transmission dynamics in...

    Authors: Anna M Stewart-Ibarra, Ángel G Muñoz, Sadie J Ryan, Efraín Beltrán Ayala, Mercy J Borbor-Cordova, Julia L Finkelstein, Raúl Mejía, Tania Ordoñez, G Cristina Recalde-Coronel and Keytia Rivero
    Citation: BMC Infectious Diseases 2014 14:610
    Content type: Research article Published on:

  41. The elderly patients affected by candidemia are growing in proportion to inpatients, but available data are limited. We aimed to determine the epidemiology, antifungal management and clinical risk factors of d...

    Authors: Hao Wang, Naizheng Liu, Mei Yin, Hui Han, Jinfeng Yue, Fan Zhang, Tichao Shan, Haipeng Guo and Dawei Wu
    Citation: BMC Infectious Diseases 2014 14:609
    Content type: Research article Published on:

  42. Major hospitals in most Chinese cities have the capability to perform HIV testing. However, it is not a routine test for all patients and, as a result, many patients are not aware of their HIV status. To under...

    Authors: Hua-Feng Xu, Hai-Zhou Zhou, Li-Xin Jiang, Na Zhang, Xuan Zhang and Xiu-Ru Guan
    Citation: BMC Infectious Diseases 2014 14:605
    Content type: Research article Published on:

  43. UNAIDS has called for greater HIV/syphilis testing worldwide just as local HIV/syphilis testing programs are cut or altered. New models are needed to make HIV/syphilis testing services sustainable while retain...

    Authors: Joseph D Tucker, Kathryn E Muessig, Rosa Cui, Cedric H Bien, Elaine J Lo, Ramon Lee, Kaidi Wang, Larry Han, Feng-Ying Liu, Li-Gang Yang, Bin Yang, Heidi Larson and Rosanna W Peeling
    Citation: BMC Infectious Diseases 2014 14:601
    Content type: Research article Published on:

  44. A rapid, sensitive and accurate laboratory diagnosis is of prime importance in suspected extrapulmonary tuberculosis (EPTB) cases. However, traditional techniques for the detection of acid-fast bacilli have li...

    Authors: Agerie Tadele, Demissew Beyene, Jemal Hussein, Tuffa Gemechu, Asaye Birhanu, Tehmina Mustafa, Aster Tsegaye, Abraham Aseffa and Lisbet Sviland
    Citation: BMC Infectious Diseases 2014 14:585
    Content type: Research article Published on:

  45. Malaria during pregnancy remains a serious public health problem. The aim of this study was to determine the prevalence and possible risk factors for malaria in pregnant women attending antenatal clinic at two...

    Authors: Mamoudou Cisse, Ibrahim Sangare, Guekoun Lougue, Sanata Bamba, Dramane Bayane and Robert Tinga Guiguemde
    Citation: BMC Infectious Diseases 2014 14:631
    Content type: Research article Published on:

  46. Refining the spatial and temporal data on malaria transmissions at a defined ecological setting has practical implications for targeted malaria control and enhancing efficient allocation of resources. Spatial ...

    Authors: Lelisa Sena, Wakgari Deressa and Ahmed Ali
    Citation: BMC Infectious Diseases 2014 14:625
    Content type: Research article Published on:

  47. Tuberculosis (TB) during pregnancy may lead to severe consequences affecting both mother and child. Prenatal care could be a very good opportunity for TB care, especially for women who have limited access to h...

    Authors: Hang Thanh Nguyen, Chiara Pandolfini, Peter Chiodini and Maurizio Bonati
    Citation: BMC Infectious Diseases 2014 14:617
    Content type: Research article Published on:

  48. Tétanos Quick Stick® (TQS) is a test for tetanus immunity screening for wounded patients in emergency departments (EDs), but represents additional costs compared with a medical interview on vaccination history...

    Authors: Dieynaba S N'Diaye, Michaël Schwarzinger, Dorothée Obach, Julien Poissy, Sophie Matheron, Enrique Casalino and Yazdan Yazdanpanah
    Citation: BMC Infectious Diseases 2014 14:603
    Content type: Research article Published on:

  49. We aimed to investigate the molecular epidemiology of Mycobacterium tuberculosis complex (MTBC) isolates in the province of Palermo, Sicily, Italy, by characterizing 183 isolates identified in the years 2004-2012...

    Authors: Celestino Bonura, Michel K Gomgnimbou, Guislaine Refrégier, Aurora Aleo, Teresa Fasciana, Anna Giammanco, Christophe Sola and Caterina Mammina
    Citation: BMC Infectious Diseases 2014 14:602
    Content type: Research article Published on:

  50. Tick borne encephalitis is the most frequent vector-transmitted infectious disease of the central nervous system in Europe and Asia. The disease caused by European subtype of tick borne encephalitis virus has ...

    Authors: Daša Stupica, Franc Strle, Tatjana Avšič-Županc, Mateja Logar, Blaž Pečavar and Fajko F Bajrović
    Citation: BMC Infectious Diseases 2014 14:614
    Content type: Case report Published on:

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BMC Infectious Diseases

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