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  1. Identification of bacterial pathogens in endophthalmitis is important to inform antibiotic selection and treatment decisions. Hemoculture bottles and polymerase chain reaction (PCR) analysis have been proposed...

    Authors: Pear Pongsachareonnont, Worawalun Honglertnapakul and Tanittha Chatsuwan
    Citation: BMC Infectious Diseases 2017 17:165
    Content type: Research article Published on:

  2. Current diagnostic methods for Schistosoma japonicum infection are insensitive for low-density infections. Therefore, a new diagnostic assay based on recombinase polymerase amplification (RPA) technology was esta...

    Authors: Weiwei Xing, Xinling Yu, Jingtao Feng, Kui Sun, Wenliang Fu, Yuanyuan Wang, Minji Zou, Wenrong Xia, Zhihong Luo, Hongbin He, Yuesheng Li and Donggang Xu
    Citation: BMC Infectious Diseases 2017 17:164
    Content type: Research article Published on:

  3. Multidrug-resistant (MDR) infections are a serious concern for children admitted to the Paediatric Intensive Care Unit (PICU). Tracheal colonization with MDR Enterobacteriaceae predisposes to respiratory infec...

    Authors: Hanna Renk, Lenja Stoll, Felix Neunhoeffer, Florian Hölzl, Matthias Kumpf, Michael Hofbeck and Dominik Hartl
    Citation: BMC Infectious Diseases 2017 17:163
    Content type: Research article Published on:

  4. HCV transmission remains high in people who inject drugs (PWID) in Montréal. New direct-acting antivirals (DAAs), highly effective and more tolerable than previous regimens, make a “Treatment as Prevention” (T...

    Authors: Anthony Cousien, Pascale Leclerc, Carole Morissette, Julie Bruneau, Élise Roy, Viet Chi Tran, Yazdan Yazdanpanah and Joseph Cox
    Citation: BMC Infectious Diseases 2017 17:162
    Content type: Research article Published on:

  5. Extensive backflow of treated wastewater caused household water contamination in a Finnish town in 2007. The drinking water of 9 500 residents became heavily polluted with faecal microbes, resulting in a large...

    Authors: Janne Laine, Outi Laine, Jukka Lumio, Jaakko Antonen, Salla Toikkanen, Mikko J. Virtanen and Markku Kuusi
    Citation: BMC Infectious Diseases 2017 17:161
    Content type: Research article Published on:

  6. Few low-income countries have virological monitoring widely available. We estimated the virological durability of first-line antiretroviral therapy (ART) after five years of follow-up among adult Ugandan and Z...

    Authors: David I. Dolling, Ruth L. Goodall, Michael Chirara, James Hakim, Peter Nkurunziza, Paula Munderi, David Eram, Dinah Tumukunde, Moira J. Spyer, Charles F. Gilks, Pontiano Kaleebu, David T. Dunn and Deenan Pillay
    Citation: BMC Infectious Diseases 2017 17:160
    Content type: Research article Published on:

  7. The most optimal antifungal agent for empiric treatment of invasive fungal diseases (IFDs) in febrile neutropenia is controversial. Our objective was evaluate the relative efficacy of antifungals for all-cause...

    Authors: Ken Chen, Qi Wang, Roy A. Pleasants, Long Ge, Wei Liu, Kangning Peng and Suodi Zhai
    Citation: BMC Infectious Diseases 2017 17:159
    Content type: Research article Published on:

  8. The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to reduce risk has been developed. This project aims to r...

    Authors: S. Raffe, H. Curtis, P. Tookey, H. Peters, A. Freedman and Y. Gilleece
    Citation: BMC Infectious Diseases 2017 17:158
    Content type: Research article Published on:

  9. Cholera outbreaks have occurred in Tanzania since 1974. To date, the genetic epidemiology of these outbreaks has not been assessed.

    Authors: Yazid Kachwamba, A. A. Mohammed, H. Lukupulo, L. Urio, M. Majigo, F. Mosha, M. Matonya, R. Kishimba, J. Mghamba, J. Lusekelo, S. Nyanga, M. Almeida, S. Li, D. Domman, S.Y. Massele and O. C. Stine
    Citation: BMC Infectious Diseases 2017 17:157
    Content type: Research article Published on:

  10. The World Health Organization recommends all countries consider screening for H. pylori to prevent gastric cancer. We therefore aimed to estimate the cost-effectiveness of a H. pylori serology-based screening pro...

    Authors: Andrea M. Teng, Giorgi Kvizhinadze, Nisha Nair, Melissa McLeod, Nick Wilson and Tony Blakely
    Citation: BMC Infectious Diseases 2017 17:156
    Content type: Research article Published on:

  11. Chlamydia trachomatis is the most common bacterial sexually transmitted infection (STI) in the United States (U.S.) [1] and remains a major public health problem. We determined the cos...

    Authors: Jared Ditkowsky, Khushal H. Shah, Margaret R. Hammerschlag, Stephan Kohlhoff and Tamar A. Smith-Norowitz
    Citation: BMC Infectious Diseases 2017 17:155
    Content type: Research article Published on:

  12. HIV-related stigma always is major obstacles to an effective HIV response worldwide. The effect of HIV-related stigma on HIV prevention and treatment is particularly serious in China. This study was to examine...

    Authors: Xin Li, Lili Yuan, Xiaoxia Li, Jingli Shi, Liying Jiang, Chundi Zhang, Xiujing Yang, Yeli Zhang, Donghui Zhao and Yashuang Zhao
    Citation: BMC Infectious Diseases 2017 17:154
    Content type: Research article Published on:

  13. Enterovirus 71 (EV-A71) shows a potential of rapid death, but the natural history of the infection is poorly known. This study aimed to examine the natural history of EV-A71 infection.

    Authors: Si-da Yang, Pei-qing Li, Yi-min Li, Wei Li, Wen-ying Lai, Cui-ping Zhu, Jian-ping Tao, Li Deng, Hong-sheng Liu, Wen-cheng Ma, Jia-ming Lu, Yan Hong, Yu-ting Liang, Jun Shen, Dan-dan Hu, Yuan-yuan Gao…
    Citation: BMC Infectious Diseases 2017 17:153
    Content type: Research article Published on:

  14. Visceral Leishmaniasis coinfection with HIV/AIDS has emerged as a series of disease pattern. It most often results in unfavorable responses to treatment, frequent relapses, and deaths. Scarce data is available...

    Authors: Mekuriaw Alemayehu, Mamo Wubshet, Nebiyu Mesfin and Abebaw Gebayehu
    Citation: BMC Infectious Diseases 2017 17:152
    Content type: Research article Published on:

  15. HIV+ patients on highly active antiretroviral therapy (HAART) with suppressed viral loads have a low incidence of HIV-associated dementia, but increased prevalence of milder forms of HIV-associated neurocognit...

    Authors: Isaac H. Solomon, Umberto De Girolami, Sukrutha Chettimada, Vikas Misra, Elyse J. Singer and Dana Gabuzda
    Citation: BMC Infectious Diseases 2017 17:151
    Content type: Research article Published on:

  16. Urinary Tract Infection (UTI) causes a serious health problem and affects millions of people worldwide. Patients with obstetric fistula usually suffer from incontinence of urine and stool, which can predispose...

    Authors: Matifan Dereje, Yimtubezinesh Woldeamanuel, Daneil Asrat and Fekade Ayenachew
    Citation: BMC Infectious Diseases 2017 17:150
    Content type: Research article Published on:

  17. Procalcitonin (PCT) has become a commonly used serum inflammatory marker. Our aim was to describe the kinetics and usefulness of serial post-operative PCT measurements to detect bacterial infection in a cohort...

    Authors: Vladimir L. Cousin, Kalinka Lambert, Shahar Trabelsi, Annick Galetto-Lacour, Klara M. Posfay-Barbe, Barbara E. Wildhaber and Valérie A. McLin
    Citation: BMC Infectious Diseases 2017 17:149
    Content type: Research article Published on:

  18. Chlamydia, gonorrhoea and syphilis are readily treatable sexually transmitted infections (STIs) which continue to occur at high rates in Australia, particularly among Aboriginal Australians. This study aimed t...

    Authors: Barbara Nattabi, Veronica Matthews, Jodie Bailie, Alice Rumbold, David Scrimgeour, Gill Schierhout, James Ward, Rebecca Guy, John Kaldor, Sandra C. Thompson and Ross Bailie
    Citation: BMC Infectious Diseases 2017 17:148
    Content type: Research article Published on:

  19. Streptococcus equi subsp. zooepidemicus is a beta-hemolytic group C streptococcus mainly causing infections in domesticated animals. Here we describe the first case of zoonotic necroti...

    Authors: Bård Reiakvam Kittang, Veronika Kuchařová Pettersen, Oddvar Oppegaard, Dag Harald Skutlaberg, Håvard Dale, Harald G. Wiker and Steinar Skrede
    Citation: BMC Infectious Diseases 2017 17:147
    Content type: Case report Published on:

  20. The U.S. Centers for Disease Control and Prevention (CDC) recommended a new regimen for treatment of latent tuberculosis (three months of weekly isoniazid and rifapentine) in late 2011. While completion rates ...

    Authors: Adelaide H. McClintock, McKenna Eastment, Christy M. McKinney, Caroline L. Pitney, Masahiro Narita, David R. Park, Shireesha Dhanireddy and Alexandra Molnar
    Citation: BMC Infectious Diseases 2017 17:146
    Content type: Research article Published on:

  21. Early diagnosis and prompt treatment is essential for an effective tuberculosis (TB) control program. However, significant proportion of cases remains undiagnosed and untreated. Delay in diagnosis and treatmen...

    Authors: Selamsew Bogale, Ermias Diro, Atsede Mazengia Shiferaw and Melaku Kindie Yenit
    Citation: BMC Infectious Diseases 2017 17:145
    Content type: Research article Published on:

  22. Middle East Respiratory Syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that causes severe morbidity and mortality. Up to date, there is no approved or licensed vaccine or antiviral medicines can...

    Authors: Shih-Chao Lin, Chi-Tang Ho, Wen-Ho Chuo, Shiming Li, Tony T. Wang and Chi-Chen Lin
    Citation: BMC Infectious Diseases 2017 17:144
    Content type: Research article Published on:

  23. Currently, there is no agreed standard for exploring the antimicrobial activity of wound antiseptics in a phase 2/ step 2 test protocol. In the present study, a standardised in-vitro test is proposed, which al...

    Authors: Kathrin Schedler, Ojan Assadian, Uta Brautferger, Gerald Müller, Torsten Koburger, Simon Classen and Axel Kramer
    Citation: BMC Infectious Diseases 2017 17:143
    Content type: Technical advance Published on:

  24. There is paucity data on the association of vitamin D deficiency (VDD) and active tuberculosis (TB) in southern Africa where the human immunodeficiency virus (HIV) is co-endemic. We examined the association of...

    Authors: Cuthbert Musarurwa, Lynn Sodai Zijenah, Doreen Zvipo Duri, Kudzie Mateveke-Dangaiso, Kudakwashe Mhandire, Maria Mary Chipiti, Marshall Wesley Munjoma and Witmore Bayayi Mujaji
    Citation: BMC Infectious Diseases 2017 17:142
    Content type: Research article Published on:

  25. We conducted a study to identify Rickettsia, Coxiella, Leptospira, Bartonella, and Chikungunya virus infections among febrile patients presenting at hospitals in Bangladesh.

    Authors: Labib Imran Faruque, Rashid Uz Zaman, Emily S. Gurley, Robert F. Massung, A. S. M. Alamgir, Renee L. Galloway, Ann M. Powers, Ying Bai, Michael Kosoy, William L. Nicholson, Mahmudur Rahman and Stephen P. Luby
    Citation: BMC Infectious Diseases 2017 17:141
    Content type: Research article Published on:

  26. Immigrants originating from intermediate and high HCV prevalence countries may be at increased risk of exposure to hepatitis C infection (HCV) in their countries of origin, however they are not routinely scree...

    Authors: Christina Greenaway, Laurent Azoulay, Robert Allard, Joseph Cox, Viet Anh Tran, Claire Nour Abou Chakra, Russ Steele and Marina Klein
    Citation: BMC Infectious Diseases 2017 17:140
    Content type: Research article Published on:

  27. Bronchiolitis is considered one of the earliest and most common causes of hospitalisation in young children. Development of molecular technologies allowed a better understanding of bronchiolitis aetiology. Res...

    Authors: Ibrahim Janahi, Anas Abdulkayoum, Fawziya Almeshwesh, Mohamed Alkuwari, Ahmed Al hammadi and Marwah Alameri
    Citation: BMC Infectious Diseases 2017 17:139
    Content type: Research article Published on:

  28. Extended Spectrum Beta- Lactamase producing organisms causing urinary tract infections (ESBL-UTI) are increasing in incidence and pose a major burden to health care. While ESBL producing Klebsiella species see...

    Authors: M. M. P. S. C. Fernando, W. A. N. V. Luke, J. K. N. D. Miththinda, R. D. S. S. Wickramasinghe, B. S. Sebastiampillai, M. P. M. L. Gunathilake, F. H. D. S. Silva and R. Premaratna
    Citation: BMC Infectious Diseases 2017 17:138
    Content type: Research article Published on:

  29. Tuberculosis is a serious public health problem worldwide. It is the leading cause of death amongst people living with HIV, and default from tuberculosis (TB) treatment in people living with HIV increases the ...

    Authors: R Cunha, M Maruza, UR Montarroyos, I Coimbra, D de B Miranda-Filho, M de F Albuquerque, HR Lacerda and RAA Ximenes
    Citation: BMC Infectious Diseases 2017 17:137
    Content type: Research article Published on:

  30. The outbreak of the 2009 H1N1 influenza pandemic (H1N1pdm) affected thousands of people in Mexico and the United States, and spread rapidly throughout the world from April 2009 to July 2010. To explore the age...

    Authors: Jin Lv, Zhen-Yong Ren, Ying-Ying Zhang, Yun-E Liu, Jun Gao, Kun Yao, Dan Feng, Zhen-Yuan Li, Xin Feng, Yun-Xi Liu and Na Jia
    Citation: BMC Infectious Diseases 2017 17:136
    Content type: Research article Published on:

  31. Phanerochaete sordida is a species of wood rotting fungus, which can degrade lignin, cellulose and hemicellulose contained in wood and other hard-to-biodegrade organic substances. Howe...

    Authors: Naoki Watanabe, Kiyofumi Ohkusu, Masaya Okuda, Osamu Imataki, Tomoya Ishii, Kiyoshi Negayama, Akira Tadokoro, Nobuyuki Kita, Takehiro Takagi, Nobuhiro Kanaji, Norimitsu Kadowaki and Shuji Bandoh
    Citation: BMC Infectious Diseases 2017 17:135
    Content type: Case report Published on:

  32. Respiratory syncytial virus (RSV) is one of the most common causes of respiratory tract infections among young children and the elderly. Timely and accurate diagnosis of respiratory tract infections improves p...

    Authors: Kevin E. Eboigbodin, Kirsi Moilanen, Sonja Elf and Mark Hoser
    Citation: BMC Infectious Diseases 2017 17:134
    Content type: Technical advance Published on:

  33. Pneumococcal carriage is the precursor for development of pneumococcal disease, and is also responsible for transmission of the organism from person-to-person. In Africa, little is known about the pneumococcus...

    Authors: Eric S. Donkor, Jennifer A. Annan, Ebenezer V. Badoe, Nicholas T. K. D. Dayie, Appiah-Korang Labi and Hans-Christian Slotved
    Citation: BMC Infectious Diseases 2017 17:133
    Content type: Research article Published on:

  34. Tuberculosis/Human immunodeficiency virus (TB/HIV) co-infection is bidirectional and synergistic which mainly affects interventions that have been taken on the area. Tb patients co-infected with HIV have poore...

    Authors: Yenework Sinshaw, Shitaye Alemu, Abel Fekadu and Mucheye Gizachew
    Citation: BMC Infectious Diseases 2017 17:132
    Content type: Research article Published on:

  35. Inappropriate use of broad-spectrum antimicrobials affects adversely both the individual patient and the general public. The aim of the study was to identify patients at risk for excessively prolonged carbapen...

    Authors: Juri Katchanov, Benno Kreuels, Florian P. Maurer, Kai Wöstmann, Johannes Jochum, Christina König, Kariem Seoudy, Holger Rohde, Ansgar W. Lohse, Dominic Wichmann, Michael Baehr, Camilla Rothe and Stefan Kluge
    Citation: BMC Infectious Diseases 2017 17:131
    Content type: Research article Published on:

  37. Ukraine is among ten countries with the highest burden of multidrug- resistant TB (MDR-TB) worldwide. Treatment success rates for MDR-TB in Ukraine remain below global success rates as reported by the World He...

    Authors: Omowunmi Aibana, Mariya Bachmaha, Viatcheslav Krasiuk, Natasha Rybak, Timothy P. Flanigan, Vasyl Petrenko and Megan B. Murray
    Citation: BMC Infectious Diseases 2017 17:129
    Content type: Research article Published on:

  38. Respiratory viruses are associated with a huge socio-economic burden and are responsible for a large proportion of acute respiratory illness in hospitalised adults. Laboratory PCR is accurate but takes at leas...

    Authors: Nathan J. Brendish, Ahalya K. Malachira and Tristan W. Clark
    Citation: BMC Infectious Diseases 2017 17:128
    Content type: Study protocol Published on:

  39. In the last 20 years routine T CD4+ lymphocyte (CD4+) cell count has proved to be a key factor to determine the stage of HIV infection and start or discontinue of prophylaxis for opportunistic infections. Howe...

    Authors: Antonio Di Biagio, Marta Ameri, Davide Sirello, Giovanni Cenderello, Enrico Di Bella, Lucia Taramasso, Barbara Giannini, Mauro Giacomini, Claudio Viscoli, Giovanni Cassola and Marcello Montefiori
    Citation: BMC Infectious Diseases 2017 17:127
    Content type: Research article Published on:

  40. The Human papillomavirus is the most common sexually transmitted virus worldwide. The objective of this study was to estimate: 1) the prevalence and the incidence of external genital warts (eGW) in a sample of...

    Authors: Barbara Suligoi, Giorgio Vittori, Maria Cristina Salfa, Laura Timelli, Dario Corsini, Giovanni Fattorini and Luciano Mariani
    Citation: BMC Infectious Diseases 2017 17:126
    Content type: Research article Published on:

  41. Diabetes complicates tuberculosis (TB) treatment including a prolonged time of sputum culture conversion to negative growth. Since 2013 in Virginia, interventions early in the treatment course have used therap...

    Authors: Yosra Alkabab, Suzanne Keller, Denise Dodge, Eric Houpt, Deborah Staley and Scott Heysell
    Citation: BMC Infectious Diseases 2017 17:125
    Content type: Research article Published on:

  42. In the course of the Ebola outbreak in West Africa that was witnessed since early 2014, the response mechanisms showed deficits in terms of timeliness, volume and adequacy. The authors were deployed in the Ebo...

    Authors: Christian Janke, Katrin Moira Heim, Florian Steiner, Moses Massaquoi, Miatta Zenabu Gbanya, Claudia Frey and Guenter Froeschl
    Citation: BMC Infectious Diseases 2017 17:124
    Content type: Correspondence Published on:

  43. As access to Xpert expands in high TB-burden settings, its performance against clinically diagnosed TB as a reference standard provides important insight as the majority of childhood TB is bacteriologically un...

    Authors: Jason M. Bacha, Katherine Ngo, Petra Clowes, Heather R. Draper, Elias N. Ntinginya, Andrew DiNardo, Chacha Mangu, Issa Sabi, Bariki Mtafya and Anna M. Mandalakas
    Citation: BMC Infectious Diseases 2017 17:123
    Content type: Research article Published on:

  44. Data on the impact of empirical antibiotic treatment (EAT) on patient outcome in a population-based setting are sparse. We assessed the association between EAT and the risk of recurrence within one year, short...

    Authors: Kim O. Gradel, Ulrich S. Jensen, Henrik C. Schønheyder, Christian Østergaard, Jenny D. Knudsen, Sonja Wehberg and Mette Søgaard
    Citation: BMC Infectious Diseases 2017 17:122
    Content type: Research article Published on:

  45. The purpose of this study was to describe what is known about HIV infection and other sexually transmitted diseases, infection transmission routes, care, and sources of information, from the viewpoint of men h...

    Authors: Tarja Suominen, Teppo Heikkinen, Marja Pakarinen, Anne-Mari Sepponen and Jari Kylmä
    Citation: BMC Infectious Diseases 2017 17:121
    Content type: Research article Published on:

  46. Due to a lack of survey of health care seeking behavior for influenza, the actual magnitude of influenza in Beijing of China has not been well described.

    Authors: Xiaoli Wang, Shuangsheng Wu, Peng Yang, Hongjun Li, Yanhui Chu, Yaqing Tang, Weiyu Hua, Haiyan Zhang, Chao Li and Quanyi Wang
    Citation: BMC Infectious Diseases 2017 17:120
    Content type: Research article Published on:

  47. Surgical site infections are commonest nosocomial infections and responsible for considerable morbidity and mortality as well as increased hospitalizations and treatment cost related to surgical operations. Th...

    Authors: Tamrat Legesse Laloto, Desta Hiko Gemeda and Sadikalmahdi Hussen Abdella
    Citation: BMC Infectious Diseases 2017 17:119
    Content type: Research article Published on:

  48. Tuberculosis is considered the second most common cause of death due to infectious agent. The currently preferred regimen for treatment of pulmonary tuberculosis (PTB) is isoniazid, rifampin, pyrazinamide, and...

    Authors: Mohammad H. Al-Shaer, Hanine Mansour, Hazem Elewa, Pascale Salameh and Fatima Iqbal
    Citation: BMC Infectious Diseases 2017 17:118
    Content type: Research article Published on:

  49. Bacterial diarrhoeal disease is among the most common causes of mortality and morbidity in children 0–59 months at the University Teaching Hospital in Lusaka, Zambia. However, most cases are treated empiricall...

    Authors: Harriet Chiyangi, John B. Muma, Sydney Malama, Joel Manyahi, Ahmed Abade, Geoffrey Kwenda and Mecky I. Matee
    Citation: BMC Infectious Diseases 2017 17:117
    Content type: Research article Published on:

  50. The occurrence of bloodstream infection (BSI) and antimicrobial resistance have been increasing in many countries. We studied trends in antimicrobial resistance and empiric antibiotic therapy at a medium-sized...

    Authors: Arne Mehl, Bjørn Olav Åsvold, Angela Kümmel, Stian Lydersen, Julie Paulsen, Ingvild Haugan, Erik Solligård, Jan Kristian Damås, Stig Harthug and Tom-Harald Edna
    Citation: BMC Infectious Diseases 2017 17:116
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Infectious Diseases 2017 17:446

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