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  1. Metabolic and cardiovascular diseases (CVD) represent a major problem in HIV infection. The aim of this study was to evaluate the relationship of HIV infection and antiretroviral therapy (ART) with circulating...

    Authors: Mario Luca Morieri, Viola Guardigni, Juana Maria Sanz, Edoardo Dalla Nora, Cecilia Soavi, Giovanni Zuliani, Laura Sighinolfi and Angelina Passaro
    Citation: BMC Infectious Diseases 2018 18:10
    Content type: Research article Published on:

  2. Control of gonorrhea in resource-limited countries, such as Indonesia, is mostly unsuccessful. Examining Neisseria gonorrhoeae (Ng) transmission networks using strain typing might help prioritizing public health ...

    Authors: I Putu Yuda Hananta, Alje Pieter van Dam, Maarten Franciscus Schim van der Loeff, Mirjam Dierdorp, Carolien Marleen Wind, Hardyanto Soebono, Henry John Christiaan de Vries and Sylvia Maria Bruisten
    Citation: BMC Infectious Diseases 2018 18:7
    Content type: Research article Published on:

  3. According to the global framework of eliminating human rabies, China is responding to achieve the target of zero human death from dog-mediated rabies by 2030. Chongqing is the largest municipality directly und...

    Authors: Li Qi, Kun Su, Tao Shen, Wenge Tang, Bangzhong Xiao, Jiang Long, Han Zhao, Xi Chen, Yu Xia, Yu Xiong, Dayong Xiao, Liangui Feng and Qin Li
    Citation: BMC Infectious Diseases 2018 18:6
    Content type: Research article Published on:

  4. Previous studies on the Burkholderia pseudomallei genetic diversity among clinical isolates from melioidosis-endemic areas have identified genetic factors contributing to differential virulence. Although it has b...

    Authors: Abdel Rahman Zueter, Zaidah Abdul Rahman, Mahmoud Abumarzouq and Azian Harun
    Citation: BMC Infectious Diseases 2018 18:5
    Content type: Research article Published on:

  5. The operating room (OR) of the hospital is a special unit that requires a relatively clean environment. The microbial concentration of an indoor OR extrinsically influences surgical site infection rates. The a...

    Authors: Ling Fu Shaw, Ian Horng Chen, Chii Shya Chen, Hui Hsin Wu, Li Shing Lai, Yin Yin Chen and Fu Der Wang
    Citation: BMC Infectious Diseases 2018 18:4
    Content type: Research article Published on:

  6. Longtime follow-up studies on patients with pharyngotonsillitis are rare. We aimed to describe the patterns of new visits for a sore throat, complications and tonsillectomy during 2 years in a cohort of patien...

    Authors: Jon Pallon, Martin Sundqvist and Katarina Hedin
    Citation: BMC Infectious Diseases 2018 18:3
    Content type: Research article Published on:

  7. Newly diagnosed HIV-positive men who have sex with men (MSM) are an important subgroup in HIV intervention. How newly diagnosed HIV-positive MSM look at HIV/AIDS is consequential and is potentially associated ...

    Authors: Xiaobing Wu, Joseph T. F. Lau, Winnie W. S. Mak, Jing Gu, Phoenix K. H. Mo and Xiaodong Wang
    Citation: BMC Infectious Diseases 2018 18:2
    Content type: Research article Published on:

  8. Presence of Mycobacterium fortuitum in respiratory tracts usually indicates mere colonization or transient infection, whereas true pulmonary infection occurs in patients with gastroesophageal disease. However, li...

    Authors: Satoshi Okamori, Takanori Asakura, Tomoyasu Nishimura, Eiko Tamizu, Makoto Ishii, Mitsunori Yoshida, Hanako Fukano, Yuichiro Hayashi, Masaki Fujita, Yoshihiko Hoshino, Tomoko Betsuyaku and Naoki Hasegawa
    Citation: BMC Infectious Diseases 2018 18:1
    Content type: Case report Published on:

  9. The overall prevalence of hepatitis B virus (HBV) infection in China is declining. The purpose of this study was to use a community-based epidemiological study to update the infection status of hepatitis B vir...

    Authors: Ping Chen, Qinfen Xie, Ting Chen, Jiawei Wu, Jie Wu, Bing Ruan, Zhiqin Zhang, Hainv Gao and Lanjuan Li
    Citation: BMC Infectious Diseases 2017 17:809
    Content type: Research article Published on:

  10. The introduction of Xpert MTB/RIF assay (Xpert) has significantly improved diagnosis of Tuberculosis (TB) in resource limited human immunodeficiency virus (HIV) endemic settings. We aimed to modify the Xpert p...

    Authors: Peter M. Mbelele, Said Aboud, Stellah G. Mpagama and Mecky I. Matee
    Citation: BMC Infectious Diseases 2017 17:808
    Content type: Technical advance Published on:

  11. The inefficiency of the current tachyzoite antigen-based serological assays for the serodiagnosis of Toxoplasma gondii infection mandates the need for acquirement of reliable and standard diagnostic reagents. Rec...

    Authors: Khalid Hajissa, Robaiza Zakaria, Rapeah Suppian and Zeehaida Mohamed
    Citation: BMC Infectious Diseases 2017 17:807
    Content type: Research article Published on:

  12. Central nervous system (CNS) infections are an important cause of childhood morbidity and mortality. The aetiologies of these potentially vaccine-preventable infections have not been well established in Cambodia.

    Authors: Paul Turner, Kuong Suy, Le Van Tan, Pora Sar, Thyl Miliya, Nguyen Thi Thu Hong, Vu Thi Ty Hang, Nguyen Thi Han Ny, Sona Soeng, Nicholas P. J. Day, H. Rogier van Doorn and Claudia Turner
    Citation: BMC Infectious Diseases 2017 17:806
    Content type: Research article Published on:

  13. The Serious Outcomes Surveillance (SOS) Network was established to monitor seasonal influenza complications among hospitalized Canadian adults and to assess the effectiveness of influenza vaccination against s...

    Authors: Melissa K. Andrew, Vivek Shinde, Todd Hatchette, Ardith Ambrose, Guy Boivin, William Bowie, Ayman Chit, Gael Dos Santos, May ElSherif, Karen Green, François Haguinet, Scott A. Halperin, Barbara Ibarguchi, Jennie Johnstone, Kevin Katz, Joanne M. Langley…
    Citation: BMC Infectious Diseases 2017 17:805
    Content type: Research article Published on:

  14. Streptococcus pneumoniae, the leading pathogen of bacterial infections in infants and the elderly, is responsible for pneumococcal diseases with severe morbidity and mortality. Emergence of d...

    Authors: Chunjiang Zhao, Zongbo Li, Feifei Zhang, Xiaobing Zhang, Ping Ji, Ji Zeng, Bijie Hu, Zhidong Hu, Kang Liao, Hongli Sun, Rong Zhang, Bin Cao, Chao Zhuo, Wei Jia, Yaning Mei, Yunzhuo Chu…
    Citation: BMC Infectious Diseases 2017 17:804
    Content type: Research article Published on:

  15. Up to one third of HIV-infected individuals with suspected TB are sputum-scarce. The Alere Determine™ TB LAM Ag lateral flow strip test can be used to diagnose TB in HIV-infected patients with advanced immunos...

    Authors: Natasha F. Sabur, Aliasgar Esmail, Mantaj S. Brar and Keertan Dheda
    Citation: BMC Infectious Diseases 2017 17:803
    Content type: Research article Published on:

  16. Prosthetic joint infection (PJI) is a major complication of total hip and total knee arthroplasty (THA, TKA). Although mycobacteria are rarely the causative pathogens, it is important to recognize and treat th...

    Authors: Anupop Jitmuang, Varah Yuenyongviwat, Keerati Charoencholvanich and Methee Chayakulkeeree
    Citation: BMC Infectious Diseases 2017 17:802
    Content type: Research article Published on:

  17. There is an established correlation between maternal education and reduction in childhood mortality. One proposed link is that an increase in maternal education will lead to an increase in health care access a...

    Authors: Jennifer Forshaw, Sarah M. Gerver, Moneet Gill, Emily Cooper, Logan Manikam and Helen Ward
    Citation: BMC Infectious Diseases 2017 17:801
    Content type: Research article Published on:

  18. While research has demonstrated the importance of a clean health care environment, there is a lack of research on the role portable medical equipment (PME) play in the transmission cycle of healthcare-acquired...

    Authors: Chetan Jinadatha, Frank C. Villamaria, John D. Coppin, Charles R. Dale, Marjory D. Williams, Ryan Whitworth and Mark Stibich
    Citation: BMC Infectious Diseases 2017 17:800
    Content type: Research article Published on:

  19. Vertical transmission can result in neonatal infection and disease. Reducing the transmission of bacterial pathogens from mother to infant may be an effective means of preventing neonatal infection, including ...

    Authors: Sarah E. Burr, Bully Camara, Claire Oluwalana, Ebrima Bojang, Christian Bottomley, Abdoulie Bojang, Robin L. Bailey, Umberto D’Alessandro and Anna Roca
    Citation: BMC Infectious Diseases 2017 17:799
    Content type: Research article Published on:

  20. Voriconazole has been used in the treatment and prophylaxis of invasive fungal infections (IFIs) while its wide use was limited by some frequent adverse events, especially neurotoxicity, hepatotoxicity and eve...

    Authors: Yuanming Xing, Lu Chen, Yan Feng, Yan Zhou, Yajing Zhai and Jun Lu
    Citation: BMC Infectious Diseases 2017 17:798
    Content type: Research article Published on:

  21. Invasive aspergillosis involving patients with neutropenia or severe immunosuppression, such as patients with hematologic malignancies is associated with high mortality. Patients with T-cell large granular lym...

    Authors: Amin T. Turki, Jassin Rashidi-Alavijeh, Jan Dürig, Guido Gerken, Peter-Michael Rath and Oliver Witzke
    Citation: BMC Infectious Diseases 2017 17:797
    Content type: Case report Published on:

  22. Nontuberculous mycobacterial (NTM) infection in immunocompromized patients is currently a growing health concern, and we aimed to examine the relative risk of NTM infection in patients with Sjögren’s syndrome ...

    Authors: Wen-Cheng Chao, Ching-Heng Lin, Tsai-Ling Liao, Yi-Ming Chen, Chiann-Yi Hsu, Jun-Peng Chen, Der-Yuan Chen and Hsin-Hua Chen
    Citation: BMC Infectious Diseases 2017 17:796
    Content type: Research article Published on:

  23. The incidence of multidrug-resistant tuberculosis (MDR-TB) is increasing and the emergence of extensively drug-resistant tuberculosis (XDR-TB) is a major challenge. Controlling resistance, reducing transmissio...

    Authors: Nontuthuko E. Maningi, Lesibana A. Malinga, John F. Antiabong, Ruth M. Lekalakala and Nontombi M. Mbelle
    Citation: BMC Infectious Diseases 2017 17:795
    Content type: Research article Published on:

  24. Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cu...

    Authors: Pauline Byakika-Kibwika, Jane Achan, Mohammed Lamorde, Carine Karera-Gonahasa, Agnes N. Kiragga, Harriet Mayanja-Kizza, Noah Kiwanuka, Sam Nsobya, Ambrose O. Talisuna and Concepta Merry
    Citation: BMC Infectious Diseases 2017 17:794
    Content type: Research article Published on:

  25. The challenges posed by Mycobacterium tuberculosis infection require the gradual removal of the pool of latent tuberculosis infection (LTBI). The current cell-immune-based diagnostic tests used to identify LTBI i...

    Authors: Fangbin Zhou, Xindong Xu, Sijia Wu, Xiaobing Cui and Weiqing Pan
    Citation: BMC Infectious Diseases 2017 17:793
    Content type: Research article Published on:

  26. To investigate the clinical characteristics and treatment outcomes in necrotizing fasciitis (NF) patients in a reconstructive unit in northeastern China.

    Authors: Jing-Chun Zhao, Bo-Ru Zhang, Kai Shi, Xi Zhang, Chun-Hui Xie, Jian Wang, Qing-Hua Yu, Xin-Xin Gao, Lei Hong and Jia-Ao Yu
    Citation: BMC Infectious Diseases 2017 17:792
    Content type: Research article Published on:

  27. Leishmania donovani is the etiological agent of visceral leishmaniasis (VL) in the Indian subcontinent. However, it is also known to cause cutaneous leishmaniasis (CL) in Sri Lanka. Sr...

    Authors: Udeshika Lakmini Kariyawasam, Angamuthu Selvapandiyan, Keshav Rai, Tasaduq Hussain Wani, Kavita Ahuja, Mizra Adil Beg, Hasitha Upendra Premathilake, Narayan Raj Bhattarai, Yamuna Deepani Siriwardena, Daibin Zhong, Guofa Zhou, Suman Rijal, Hira Nakhasi and Nadira D. Karunaweera
    Citation: BMC Infectious Diseases 2017 17:791
    Content type: Research article Published on:

  28. Gardasil®, a quadrivalent vaccine targeting low-risk (6, 11) and high-risk (16, 18) human papillomaviruses (HPV), has been offered to 11–14 year-old schoolgirls in Switzerland since 2008. To evaluate its succe...

    Authors: Martine Jacot-Guillarmod, Jérôme Pasquier, Gilbert Greub, Massimo Bongiovanni, Chahin Achtari and Roland Sahli
    Citation: BMC Infectious Diseases 2017 17:790
    Content type: Research article Published on:

  29. “Alice in Wonderland” syndrome (AIWS) is a rare neurological abnormality characterized by distortions of visual perceptions, body schema and experience of time. AIWS has been reported ...

    Authors: Benjamin Momo Kadia, Cyril Jabea Ekabe and Ettamba Agborndip
    Citation: BMC Infectious Diseases 2017 17:789
    Content type: Case report Published on:

  30. Provision of information plays a critical role in supporting patients to be engaged or empowered to be involved with infection prevention measures in hospitals. This explorative study evaluated the suitability...

    Authors: J. Park and H. Seale
    Citation: BMC Infectious Diseases 2017 17:788
    Content type: Research article Published on:

  31. Co-infections are common in childhood community acquired pneumonia (CAP). However, their etiological pattern and clinical impact remains inconclusive.

    Authors: Wujun Jiang, Min Wu, Jing Zhou, Yuqing Wang, Chuangli Hao, Wei Ji, Xinxing Zhang, Wenjing Gu and Xuejun Shao
    Citation: BMC Infectious Diseases 2017 17:787
    Content type: Research article Published on:

  32. Hepatitis B vaccination for healthcare workers (HCWs) is a key component of the WHO Hepatitis B Elimination Strategy 2016–2021. Data on current hepatitis B vaccine coverage among health care workers in Sub-Sah...

    Authors: Dotto Aaron, Tumaini J. Nagu, John Rwegasha and Ewaldo Komba
    Citation: BMC Infectious Diseases 2017 17:786
    Content type: Research article Published on:

  33. Respiratory syncytial virus (RSV) infection constitutes a substantial disease burden in the general population. However, the risk of death for RSV infection has been rarely evaluated with confounders or comorb...

    Authors: Yong Shik Kwon, Sun Hyo Park, Mi-Ae Kim, Hyun Jung Kim, Jae Seok Park, Mi Young Lee, Choong Won Lee, Sonila Dauti and Won-Il Choi
    Citation: BMC Infectious Diseases 2017 17:785
    Content type: Research article Published on:

  34. The last decade was marked by major advances in HCV treatment with the introduction of first wave protease inhibitors (1st-wave PIs, telaprevir or boceprevir) in 2011 and second direct-acting antivirals (2nd-w...

    Authors: Cécile Brouard, Marjorie Boussac-Zarebska, Christine Silvain, Julien Durand, Victor de Lédinghen, Josiane Pillonel and Elisabeth Delarocque-Astagneau
    Citation: BMC Infectious Diseases 2017 17:784
    Content type: Research article Published on:

  35. Studies have shown that radiation from radiotherapy increases the yeast colonization of patients. However it is not clear, if such radiation alters the yeast itself. The aim of the present study was therefore ...

    Authors: Eliane Martins da Silva, Elaine Sciuniti Benites Mansano, Ellen Sayuri Miazima, Francielle Abigail Vilugron Rodrigues, Luzmarina Hernandes and Terezinha Inez Estivalet Svidzinski
    Citation: BMC Infectious Diseases 2017 17:783
    Content type: Research article Published on:

  36. Chlamydia infections are common in both men and women, are often asymptomatic and can cause serious complications. Repeat testing in high-risk groups is therefore indicated. In the Netherlands, guidelines on r...

    Authors: Maartje Visser, Fleur van Aar, Femke D. H. Koedijk, Carolina J. G. Kampman and Janneke C. M. Heijne
    Citation: BMC Infectious Diseases 2017 17:782
    Content type: Research article Published on:

  37. Artemisinin-based combination therapies (ACTs) have remained efficacious treatments of acute falciparum malaria in many endemic areas but there is little evaluation of factors contributing to the anaemia of ac...

    Authors: Akintunde Sowunmi, Bayo Fatunmbi, Kazeem Akano, Olubunmi A. Wewe, Chimere Agomo, Finomo Finomo, Joy Ebenebe, Nma Jiya, Jose Ambe, Robinson Wammanda, Godwin Ntadom, Olugbenga Mokuolu, George Emechebe, Nnenna Ezeigwe, Adejumoke I. Ayede, Elsie O. Adewoye…
    Citation: BMC Infectious Diseases 2017 17:781
    Content type: Research article Published on:

  38. Prospective studies have shown that 80% of acute hepatitis C virus (HCV) cases progress to chronic infection; approximately 10-20% of patients with these conditions will develop liver cirrhosis within 2 to 3 d...

    Authors: Caroline Manchiero, Arielle Karen da Silva Nunes, Mariana Carvalheiro Magri, Bianca Peixoto Dantas, Celso Carmo Mazza, Antonio Alci Barone and Fátima Mitiko Tengan
    Citation: BMC Infectious Diseases 2017 17:780
    Content type: Research article Published on:

  39. Cholera is a diarrheal disease that produces rapid dehydration. The infection is a significant cause of mortality and morbidity. Oral cholera vaccine (OCV) has been propagated for the prevention of cholera. Ev...

    Authors: Patrick G. Ilboudo and Jean-Bernard Le Gargasson
    Citation: BMC Infectious Diseases 2017 17:779
    Content type: Research article Published on:

  40. The recent emergence of Zika virus (ZIKV) in Brazil and its precipitous expansion throughout the Americas has highlighted the urgent need for a rapid and reliable on-site diagnostic assay suitable for viral de...

    Authors: Mariano Carossino, Yanqiu Li, Pei-Yu A. Lee, Chuan-Fu Tsai, Pin-Hsing Chou, Dennis Williams, Ashley Skillman, R. Frank Cook, Grayson Brown, Hsiao-Fen G. Chang, Hwa-Tang T. Wang and Udeni B. R. Balasuriya
    Citation: BMC Infectious Diseases 2017 17:778
    Content type: Research article Published on:

  42. To evaluate in vitro susceptibilities of aerobic and facultative Gram-negative bacterial (GNB) isolates from intra-abdominal infections (IAIs) to 12 selected antimicrobials in Chinese hospitals from 2012 to 2014.

    Authors: Hui Zhang, Qiwen Yang, Kang Liao, Yuxing Ni, Yunsong Yu, Bijie Hu, Ziyong Sun, Wenxiang Huang, Yong Wang, Anhua Wu, Xianju Feng, Yanping Luo, Yunzhuo Chu, Shulan Chen, Bin Cao, Jianrong Su…
    Citation: BMC Infectious Diseases 2017 17:776
    Content type: Research article Published on:

  43. Mathematical models offer the possibility to investigate the infectious disease dynamics over time and may help in informing design of studies. A systematic review was performed in order to determine to what e...

    Authors: Sereina A. Herzog, Stéphanie Blaizot and Niel Hens
    Citation: BMC Infectious Diseases 2017 17:775
    Content type: Research article Published on:

  44. Streptococcus pyogenes (group A Streptococcus [GAS]) is a major human pathogen that causes a wide spectrum of clinical manifestations. Although invasive GAS (iGAS) infections are relat...

    Authors: Tsuyoshi Sekizuka, Emina Nai, Tomohiro Yoshida, Shota Endo, Emi Hamajima, Satoka Akiyama, Yoji Ikuta, Natsuko Obana, Takahiro Kawaguchi, Kenta Hayashi, Masahiro Noda, Tomoko Sumita, Masayuki Kokaji, Tatsuo Katori, Masanori Hashino, Kunihiro Oba…
    Citation: BMC Infectious Diseases 2017 17:774
    Content type: Case report Published on:

  45. Diarrheagenic Escherichia coli (DEC) are important bacterial causes of childhood diarrhea in Brazil, but its impact in adults is unknown. This study aimed at investigating DEC among children and adults living in ...

    Authors: Liliana Cruz Spano, Keyla Fonseca da Cunha, Mariane Vedovatti Monfardini, Rita de Cássia Bergamaschi Fonseca and Isabel Christina Affonso Scaletsky
    Citation: BMC Infectious Diseases 2017 17:773
    Content type: Research article Published on:

  46. Unlike influenza viruses, little is known about the prevalence and seasonality of other respiratory viruses because laboratory surveillance for non-influenza respiratory viruses is not well developed or suppor...

    Authors: Xueying Zheng, Zhengyu Song, Yapeng Li, Juanjuan Zhang and Xi-Ling Wang
    Citation: BMC Infectious Diseases 2017 17:772
    Content type: Research article Published on:

  47. The HIV-1 DNA reservoir is an important marker that reflects viro-immunological status and can be affected by multiple viral or cellular factors. Determining the potential factors associated with the size of t...

    Authors: Yongsong Yue, Nidan Wang, Yang Han, Ting Zhu, Jing Xie, Zhifeng Qiu, Xiaojing Song, Yanling Li, Jean-Pierre Routy, Jianhua Wang and Taisheng Li
    Citation: BMC Infectious Diseases 2017 17:771
    Content type: Research article Published on:

  48. In sub-Saharan Africa, efforts to control antimicrobial resistance (AMR) are aggravated by unregulated drug sales and use, and high connectivity between human, livestock, and wildlife populations. Our previous...

    Authors: Casey J. Roulette, Mark A. Caudell, Jennifer W. Roulette, Robert J. Quinlan, Marsha B. Quinlan, Murugan Subbiah and Douglas R. Call
    Citation: BMC Infectious Diseases 2017 17:770
    Content type: Research article Published on:

  49. Some sexually transmitted infectious agents, such as Chlamydia trachomatis and Herpes simplex, cause local inflammation, and could contribute to Human Papillomavirus (HPV) and cervical lesion progression. Thus, t...

    Authors: Aline Teixeira Amorim, Lucas Miranda Marques, Guilherme Barreto Campos, Tássia Neves Lobão, Vanesca de Souza Lino, Ricardo Cesar Cintra, Maria Antonieta Andreoli, Luisa Lina Villa, Enrique Boccardo, Antonio Carlos Ricardo Braga Junior, Rossana Verónica Mendoza López, Djanilson Barbosa dos Santos, Gerson Maciel de Souza, Carla Cristina Romano and Jorge Timenetsky
    Citation: BMC Infectious Diseases 2017 17:769
    Content type: Research article Published on:

  50. Respiratory syncytial virus (RSV) is the most important cause of severe acute respiratory tract infection in young children. Alere i RSV is a novel molecular rapid test which identifies respiratory syncytial v...

    Authors: Sarah Valerie Schnee, Johannes Pfeil, Clara Marlene Ihling, Julia Tabatabai and Paul Schnitzler
    Citation: BMC Infectious Diseases 2017 17:767
    Content type: Research article Published on:

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