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  1. Leishmaniasis, a vector borne tropical/subtropical disease caused by the protozoan Leishmania is transmitted to humans by sandfly vectors Phlebotomus and Lutzomyia. The principal form found in Sri Lanka is cutane...

    Authors: Devika Iddawela, Sanura Malinda Pallegoda Vithana, Dhilma Atapattu and Lanka Wijekoon
    Citation: BMC Infectious Diseases 2018 18:108
    Content type: Research article Published on:

  2. Various studies have identified numerous factors associated with poor clinical outcomes in patients with Staphylococcus aureus bacteraemia (SAB). A new study was created to provide deeper insight into in-hospital...

    Authors: Natasha E. Holmes, J. Owen Robinson, Sebastiaan J. van Hal, Wendy J. Munckhof, Eugene Athan, Tony M. Korman, Allen C. Cheng, John D. Turnidge, Paul D. R. Johnson and Benjamin P. Howden
    Citation: BMC Infectious Diseases 2018 18:107
    Content type: Research article Published on:

  3. In 2012, the World Health Organization launched guidelines for systematically investigating contacts of persons with infectious tuberculosis (TB) in low- and middle-income countries. As such, it is necessary t...

    Authors: Gladys Kigozi, Michelle Engelbrecht, Christo Heunis and André Janse van Rensburg
    Citation: BMC Infectious Diseases 2018 18:106
    Content type: Research article Published on:

  4. Mycobacterium tuberculosis (M. tuberculosis) disease is a generally well-known problem among immunocompromised adults and children. In pediatric oncology, only few cases of M. tuberculosis disease are reported so...

    Authors: Karoline van de Loo, Stefan Balzer, Colin R. MacKenzie, Thomas M. Boemers, Monika Ortmann, Jörg Schaper, Arndt Borkhardt, Hans-Jürgen Laws and Michaela Kuhlen
    Citation: BMC Infectious Diseases 2018 18:105
    Content type: Case report Published on:

  5. Monitoring the treatment outcomes of tuberculosis and determining the specific factors associated with unsuccessful treatment outcome are essential to evaluate the effectiveness of tuberculosis control program...

    Authors: Yufeng Wen, Zhiping Zhang, Xianxiang Li, Dan Xia, Jun Ma, Yuanyuan Dong and Xinwei Zhang
    Citation: BMC Infectious Diseases 2018 18:104
    Content type: Research article Published on:

  6. Monovalent varicella vaccines have been available in the Veneto Region of Italy since 2004. In 2006, a single vaccine dose was added to the immunisation calendar for children aged 14 months. ProQuad®, a quadri...

    Authors: Carlo Giaquinto, Giovanni Gabutti, Vincenzo Baldo, Marco Villa, Lara Tramontan, Nadia Raccanello, Francesca Russo, Chiara Poma, Antonio Scamarcia, Luigi Cantarutti, Rebecca Lundin, Emilia Perinetti, Xavier Cornen, Stéphane Thomas, Céline Ballandras, Audrey Souverain…
    Citation: BMC Infectious Diseases 2018 18:103
    Content type: Research article Published on:

  7. Growth-based drug susceptibility testing (DST) is the reference standard for diagnosing drug-resistant tuberculosis (TB), but standard time to result (TTR) is typically ≥ 3 weeks. Rapid tests can reduce that T...

    Authors: Erik J. Groessl, Theodore G. Ganiats, Naomi Hillery, Andre Trollip, Roberta L. Jackson, Donald G. Catanzaro, Timothy C. Rodwell, Richard S. Garfein, Camilla Rodrigues, Valeriu Crudu, Thomas C. Victor and Antonino Catanzaro
    Citation: BMC Infectious Diseases 2018 18:102
    Content type: Research article Published on:

  8. The inflammasome responses in Treponema pallidum infection have been poorly understood to date. This study aimed to investigate the expression of the nucleotide-binding leucine-rich receptor protein 3 (NLRP3) inf...

    Authors: Li-Rong Lin, Yao Xiao, Wei Liu, Yu-Yan Chen, Xiao-Zhen Zhu, Zheng-Xiang Gao, Kun Gao, Man-Li Tong, Hui-Lin Zhang, Shu-Lian Li, Hui-Ling Lin, Wen-Dong Li, Xian-Ming Liang, Yong Lin, Li-Li Liu and Tian-Ci Yang
    Citation: BMC Infectious Diseases 2018 18:101
    Content type: Research article Published on:

  9. Until now, there is non-specific treatment, and exploring early and novel biomarkers to determine the disease severity and prognosis of hemorrhagic fever with renal syndrome (HFRS) would be of importance for c...

    Authors: Jing Li, Hong Du, Xue-Fan Bai, Xiao-Yan Wang, Ying Zhang, Hong Jiang and Ping-Zhong Wang
    Citation: BMC Infectious Diseases 2018 18:100
    Content type: Research article Published on:

  10. Concurrent presence of dengue hemorrhagic fever (DHF), tropical pyomyositis and septicemia due to methicillin-resistant Staphylococcus aureus (MRSA) in a previously healthy person has never been reported. These t...

    Authors: N. D. B. Ehelepola, R. K. G. M. Rajapaksha, D. M. U. B. Dhanapala, T. D. K. Thennekoon and S. Ponnamperuma
    Citation: BMC Infectious Diseases 2018 18:99
    Content type: Case report Published on:

  11. The emergence of extensively drug-resistant tuberculosis (XDR-TB) has raised public health concern for global TB control. Although multi drug-resistant tuberculosis (MDR- TB) prevalence and associated genetic ...

    Authors: Amal Oudghiri, Hind Karimi, Fouad Chetioui, Fathiah Zakham, Jamal Eddine Bourkadi, My Driss Elmessaoudi, Amin Laglaoui, Imane Chaoui and Mohammed El Mzibri
    Citation: BMC Infectious Diseases 2018 18:98
    Content type: Research article Published on:

  12. Characteristics of hepatitis B (HBV) and delta (HDV) coinfection in various geographical regions, including Israel, remain unclear. Here we studied HDV seroprevalence in Israel, assessed HDV/HBV viral loads, c...

    Authors: Rachel Shirazi, Daniela Ram, Aviya Rakovsky, Efrat Bucris, Yael Gozlan, Yaniv Lustig, Pninit Shaked-Mishan, Orit Picard, Yonat Shemer-Avni, Haim Ben-Zvi, Ora Halutz, Yoav Lurie, Ella Veizman, Matthias Carlebach, Marius Braun, Michal Cohen- Naftaly…
    Citation: BMC Infectious Diseases 2018 18:97
    Content type: Research article Published on:

  13. The Indonesian region of Aceh was the area most severely affected by the earthquake and tsunami of 26 December 2004. Department of Health data reveal an upward trend of dengue cases in Aceh since the events of...

    Authors: Harapan Harapan, Yogambigai Rajamoorthy, Samsul Anwar, Aslam Bustamam, Arsil Radiansyah, Pradiba Angraini, Riny Fasli, Salwiyadi Salwiyadi, Reza Akbar Bastian, Ade Oktiviyari, Imaduddin Akmal, Muhammad Iqbalamin, Jamalul Adil, Fenni Henrizal, Darmayanti Darmayanti, Rovy Pratama…
    Citation: BMC Infectious Diseases 2018 18:96
    Content type: Research article Published on:

  14. We aimed to describe anatomic site-specific concordance of gonococcal infections in partnerships of men who have sex with men (MSM).

    Authors: Vincent J. Cornelisse, Lei Zhang, Matthew Law, Marcus Y. Chen, Catriona S. Bradshaw, Clare Bellhouse, Christopher K. Fairley and Eric P. F. Chow
    Citation: BMC Infectious Diseases 2018 18:95
    Content type: Research article Published on:

  15. Tuberculosis (TB) recurrence represents a challenge to control programs. In low incidence countries, the prevailing risk factors leading to recurrence are poorly characterised.

    Authors: Andrew Rosser, Matthew Richardson, Martin J. Wiselka, Robert C. Free, Gerrit Woltmann, Galina V. Mukamolova and Manish Pareek
    Citation: BMC Infectious Diseases 2018 18:94
    Content type: Research article Published on:

  16. The World Health Organization recommends that countries conduct two phase evaluations of HIV rapid tests (RTs) in order to come up with the best algorithms. In this report, we present the first ever such evalu...

    Authors: Pontiano Kaleebu, Paul Kato Kitandwe, Tom Lutalo, Aminah Kigozi, Christine Watera, Mary Bridget Nanteza, Peter Hughes, Joshua Musinguzi, Alex Opio, Robert Downing and Edward Katongole Mbidde
    Citation: BMC Infectious Diseases 2018 18:93
    Content type: Research article Published on:

  17. Cross-reacting antibodies enhanced dengue infection in humans and antibody dependent enhancement (ADE) have been proposed as early mechanisms underlying DHF/DSS. However, the duration of dengue IgG antibodies ...

    Authors: Shuying Luo, Weihong Cui, Chan Li, Feng Ling, Tao Fu, Qiyong Liu, Jiangping Ren and Jimin Sun
    Citation: BMC Infectious Diseases 2018 18:92
    Content type: Research article Published on:

  18. Expressed human milk (EHM) feed preparation areas represent a potential source of unintentional nosocomial infection. Daily disinfection of environmental surfaces remains an essential intervention to mitigate ...

    Authors: Ricky Dippenaar and Johan Smith
    Citation: BMC Infectious Diseases 2018 18:91
    Content type: Research article Published on:

  19. The Dengue Score is a model for predicting pleural effusion and/or ascites and uses the hematocrit (Hct), albumin concentration, platelet count and aspartate aminotransferase (AST) ratio as independent variabl...

    Authors: Suhendro Suwarto, Mohammad Jauharsyah Hidayat and Bing Widjaya
    Citation: BMC Infectious Diseases 2018 18:90
    Content type: Research article Published on:

  20. Fluoroquinolones (FQ) are increasingly prescribed for children, despite being labeled for only a limited number of labeled pediatric indications. In this multicenter retrospective drug utilization study, we an...

    Authors: Kevin Meesters, Reiner Mauel, Evelyn Dhont, Johan Vande Walle and Pauline De Bruyne
    Citation: BMC Infectious Diseases 2018 18:89
    Content type: Research article Published on:

  21. Socio-economic, demographic factors and Knowledge Attitude Practices (KAPs) have been recognized as critical factors that influence the incidence and transmission of dengue epidemics. However, studies that cha...

    Authors: Lahiru Udayanga, Nayana Gunathilaka, M. C. M. Iqbal, Kusumawathie Pahalagedara, Upali S. Amarasinghe and Wimaladharma Abeyewickreme
    Citation: BMC Infectious Diseases 2018 18:88
    Content type: Research article Published on:

  22. Smear microscopy lacks sensitivity especially in HIV co-infection, resulting in undiagnosed tuberculosis (TB) and high mortality. The loop-mediated isothermal amplification (TB-LAMP) assay can be staged with m...

    Authors: Lydia Nakiyingi, Prossy Nakanwagi, Jessica Briggs, Tifu Agaba, Frank Mubiru, Mark Mugenyi, Willy Ssengooba, Moses L. Joloba and Yukari C. Manabe
    Citation: BMC Infectious Diseases 2018 18:87
    Content type: Research article Published on:

  23. Colonization with Staphylococcus aureus is a well-defined risk factor for disease in hospitals, which can range from minor skin infections to severe, systemic diseases. However, the generalizability of this findi...

    Authors: Marina W. Kim, Ben K. Greenfield, Robert E. Snyder, Craig M. Steinmaus and Lee W. Riley
    Citation: BMC Infectious Diseases 2018 18:86
    Content type: Research article Published on:

  24. Right-sided infective endocarditis (RSIE) is an uncommon diagnosis accounting for less than 10% of cases of infective endocarditis. Optimal management for severely ill patients with RSIE remains challenging be...

    Authors: Hugues Georges, Olivier Leroy, Norair Airapetian, Nicolas Lamblin, Elie Zogheib, Patrick Devos and Sebastien Preau
    Citation: BMC Infectious Diseases 2018 18:85
    Content type: Research article Published on:

  25. Oral cholera vaccine (OCV) is a feasible tool to prevent or mitigate cholera outbreaks. A better understanding of the vaccine’s efficacy among different age groups and how rapidly its protection wanes could he...

    Authors: Youyi Fong, M. Elizabeth Halloran, Jin Kyung Park, Florian Marks, John D. Clemens and Dennis L. Chao
    Citation: BMC Infectious Diseases 2018 18:84
    Content type: Research article Published on:

  26. Non-adherence to Highly Active Antiretroviral Therapy (HAART) is one of the factors for treatment failure in human immunodeficiency virus (HIV) infected patients in developing countries. The main objective of ...

    Authors: Awoke Seyoum Tegegne, Principal Ndlovu and Temesgen Zewotir
    Citation: BMC Infectious Diseases 2018 18:83
    Content type: Research article Published on:

  27. The exponential growth in the reach and development of new technologies over the past decade means that mobile technologies and social media play an increasingly important role in service delivery models to ma...

    Authors: Julianita Purnomo, Katherine Coote, Limin Mao, Ling Fan, Julian Gold, Raghib Ahmad and Lei Zhang
    Citation: BMC Infectious Diseases 2018 18:82
    Content type: Research article Published on:

  28. Human fecal carriage of Enterobacteriaceae possessing mobilized colistin resistance genes (mcr-1 and mcr-2) remains obscure in Hong Kong. As part of routine surveillance on emerging antibiotic resistance, we cond...

    Authors: Wai-Sing Chan, Chun-Hang Au, Dona N. Ho, Tsun-Leung Chan, Edmond Shiu-Kwan Ma and Bone Siu-Fai Tang
    Citation: BMC Infectious Diseases 2018 18:81
    Content type: Research article Published on:

  29. Natural killer (NK) cells play cytotoxic roles by targeting tumor cells or virus infected cells, they also play regulatory roles by secreting cytokines and chemokines. Transforming growth factor (TGF)-β and in...

    Authors: Yongjun Jiang, Mei Yang, Xiaojuan Sun, Xi Chen, Meichen Ma, Xiaowan Yin, Shi Qian, Zining Zhang, Yajing Fu, Jing Liu, Xiaoxu Han, Junjie Xu and Hong Shang
    Citation: BMC Infectious Diseases 2018 18:80
    Content type: Research article Published on:

  30. In 2016, the World Health Organisation set a goal to eliminate viral hepatitis by 2030. Robust epidemiological information underpins all efforts to achieve elimination and this systematic review provides estim...

    Authors: Abby May Falla, Sanne Henrietta Ina Hofstraat, Erika Duffell, Susan Josien Maria Hahné, Lara Tavoschi and Irene Karen Veldhuijzen
    Citation: BMC Infectious Diseases 2018 18:79
    Content type: Research article Published on:

  31. From October 2010 through February 2016, Arizona conducted surveillance for severe acute respiratory infections (SARI) among adults hospitalized in the Arizona-Mexico border region. There are few accurate mort...

    Authors: Steve R. Barnes, Zimy Wansaula, Kristen Herrick, Eyal Oren, Kacey Ernst, Sonja J. Olsen and Mariana G. Casal
    Citation: BMC Infectious Diseases 2018 18:78
    Content type: Research article Published on:

  32. Measles is one of the leading causes of death among young children even though a safe and cost-effective vaccine is available. Timely analysis of measles surveillance data is crucial for epidemic control and c...

    Authors: Misganu Endriyas, Tarekegn Solomon, Bekele Belayhun and Emebet Mekonnen
    Citation: BMC Infectious Diseases 2018 18:77
    Content type: Research article Published on:

  33. The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limited settings. The ne...

    Authors: Alain Amstutz, Bienvenu Lengo Nsakala, Fiona Vanobberghen, Josephine Muhairwe, Tracy Renée Glass, Beatrice Achieng, Mamorena Sepeka, Katleho Tlali, Lebohang Sao, Kyaw Thin, Thomas Klimkait, Manuel Battegay and Niklaus Daniel Labhardt
    Citation: BMC Infectious Diseases 2018 18:76
    Content type: Study protocol Published on:

  34. Persons with chronic hepatitis B (CHB) infection were reported to suffer severe disease after hepatitis E virus (HEV) superinfection, but the studies regarding HEV seroprevalence in this population were limite...

    Authors: Li Zhang, Zechun Jiang, Jingjing Lv, Jiaye Liu, Bingyu Yan, Yi Feng, Li Li, Guomin Zhang, Fuzhen Wang and Aiqiang Xu
    Citation: BMC Infectious Diseases 2018 18:75
    Content type: Research article Published on:

  35. People who inject drugs (PWID) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). Treatment of PWID is complex due to addiction, mental illness, poverty, ho...

    Authors: Matthew J. Akiyama, Linda Agyemang, Julia H. Arnsten, Moonseong Heo, Brianna L. Norton, Bruce R. Schackman, Benjamin P. Linas and Alain H. Litwin
    Citation: BMC Infectious Diseases 2018 18:74
    Content type: Study protocol Published on:

  36. Melioidosis, the disease caused by Burkholderia pseudomallei is endemic in the Northeastern part of Thailand, South-East Asia, and Northern Australia. The pelvic involvement of disease is rare even in an endemic ...

    Authors: Pattaranit Nernsai, Areepan Sophonsritsuk, Srithean Lertvikool, Artit Jinawath and Maria Nina Chitasombat
    Citation: BMC Infectious Diseases 2018 18:73
    Content type: Case report Published on:

  37. Acute respiratory infections (ARIs) are a great public health challenge globally. The prevalence of respiratory viruses in patients with ARIs attending at different hospital settings is fully undetermined.

    Authors: Jianxing Yu, Zhengde Xie, Tiegang Zhang, Yanqin Lu, Hongwei Fan, Donghong Yang, Thomas Bénet, Philippe Vanhems, Kunling Shen, Fang Huang, Jinxiang Han, Taisheng Li, Zhancheng Gao, Lili Ren and Jianwei Wang
    Citation: BMC Infectious Diseases 2018 18:72
    Content type: Research article Published on:

  38. Tuberculosis (TB) transmission is influenced by patient-related risk, environment and bacteriological factors. We determined the risk factors associated with cluster size of IS6110 RFLP based genotypes of Mycobac...

    Authors: Renata Lyrio Peres, Solange Alves Vinhas, Fabíola Karla Correa Ribeiro, Moisés Palaci, Thiago Nascimento do Prado, Bárbara Reis-Santos, Eliana Zandonade, Philip Noel Suffys, Jonathan E. Golub, Lee W. Riley and Ethel Leonor Maciel
    Citation: BMC Infectious Diseases 2018 18:71
    Content type: Research article Published on:

  39. Although atypical mycobacteria had been increasingly found in various ocular infections in the past decades, a slow-growing Mycobacterium haemophilum (M. haemophilum) was scarcely reported. Similar to tuberculous...

    Authors: Warinyupa Pinitpuwadol, Sucheera Sarunket, Sutasinee Boonsopon, Nattaporn Tesavibul and Pitipol Choopong
    Citation: BMC Infectious Diseases 2018 18:70
    Content type: Case report Published on:

  41. Nosocomial infections are a major setback in the healthcare delivery system especially in developing countries due to the limited resources. The roles played by medical care equipment and work surfaces in the ...

    Authors: Ivan Sserwadda, Mathew Lukenge, Bashir Mwambi, Gerald Mboowa, Apollo Walusimbi and Farouk Segujja
    Citation: BMC Infectious Diseases 2018 18:68
    Content type: Research article Published on:

  42. People with diabetes may be at higher risk for acquiring infections through both glucose-dependent and biologic pathways independent of glycemic control. Our aim was to estimate the association between diabete...

    Authors: Waseem Abu-Ashour, Laurie K Twells, James E Valcour and John-Michael Gamble
    Citation: BMC Infectious Diseases 2018 18:67
    Content type: Research article Published on:

  43. Severe fever with thrombocytopenia syndrome (SFTS) is a severe viral disease caused by SFTSV. It is important to estimate the rate of missed SFTS diagnosis and to further understand the actual incidence in hig...

    Authors: Xiaoxia Huang, Shiwen Wang, Xianjun Wang, Yong Lyu, Mei Jiang, Deying Chen, Kaichun Li, Jingyu Liu, Shaoyu Xie, Tao Lyu, Jie Sun, Pengpeng Xu, Minghua Cao, Mifang Liang and Dexin Li
    Citation: BMC Infectious Diseases 2018 18:66
    Content type: Research article Published on:

  44. In the last decades, probiotics have been widely used as food supplements because of their putative beneficial health effects. They are generally considered safe but rare reports of serious infections caused b...

    Authors: Evangelo Boumis, Alessandro Capone, Vincenzo Galati, Carolina Venditti and Nicola Petrosillo
    Citation: BMC Infectious Diseases 2018 18:65
    Content type: Case report Published on:

  45. Tuberculosis (TB) remains one of the major infectious diseases worldwide. Adverse reactions are common during TB treatment. Few reports, however, are available on treatment-related acute biliary events (ABEs),...

    Authors: Lih-Yu Chang, Chih-Hsin Lee, Chia-Hao Chang, Ming-Chia Lee, Meng-Rui Lee, Jann-Yuan Wang and Li-Na Lee
    Citation: BMC Infectious Diseases 2018 18:64
    Content type: Research article Published on:

  46. Diarrhea is the leading infectious cause of childhood morbidity and mortality. Among bacterial agents, diarrheagenic Escherichia coli (DEC) is the major causal agent of childhood diarrhea in developing countries,...

    Authors: Yu Zhou, Xuhui Zhu, Hongyan Hou, Yanfang Lu, Jing Yu, Lie Mao, Liyan Mao and Ziyong Sun
    Citation: BMC Infectious Diseases 2018 18:63
    Content type: Research article Published on:

  47. Previous studies have shown that the increased coverage of antiretroviral therapy (ART) could reduce the community viral load (CVL) and reduce the occurrence of new HIV infections. However, the impact on the r...

    Authors: Lin He, Jiezhe Yang, Qiaoqin Ma, Jiafeng Zhang, Yun Xu, Yan Xia, Wanjun Chen, Hui Wang, Jinlei Zheng, Jun Jiang, Yan Luo, Ke Xu, Xingliang Zhang, Shichang Xia and Xiaohong Pan
    Citation: BMC Infectious Diseases 2018 18:62
    Content type: Research article Published on:

  48. In Colombia, the dengue virus (DENV) has been endemic for decades, and with the recent entry of the chikungunya virus (CHIKV) (2014) and the Zika virus (ZIKV) (2015), health systems are overloaded because the ...

    Authors: Marlen Yelitza Carrillo-Hernández, Julian Ruiz-Saenz, Lucy Jaimes Villamizar, Sergio Yebrail Gómez-Rangel and Marlen Martínez-Gutierrez
    Citation: BMC Infectious Diseases 2018 18:61
    Content type: Research article Published on:

  49. Studies have shown that the prognosis of the treatment of methicillin-susceptible S. aureus (MSSA) with glycopeptides is inferior compared to treatment with β-lactam. However, there are only few studies comparing...

    Authors: Dong Hyun Oh, Jung Ju Kim, Jinnam Kim, Hye Seong, Se Ju Lee, Yong Chan Kim, Eun Jin Kim, In Young Jung, Woo Yong Jeong, Su Jin Jeong, Nam Su Ku, Sang Hoon Han, Jun Yong Choi, Young Goo Song and June Myung Kim
    Citation: BMC Infectious Diseases 2018 18:60
    Content type: Research article Published on:

  50. Early presentation for HIV care is vital as an initial tread in the UNAIDS 90–90–90 targets. However, late presentation for HIV care (LP) challenges achieving the targets. This study assessed the prevalence, t...

    Authors: Hailay Abrha Gesesew, Paul Ward, Kifle Woldemichael and Lillian Mwanri
    Citation: BMC Infectious Diseases 2018 18:59
    Content type: Research article Published on:

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