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  1. Globally recommended measures for comprehensive tuberculosis (TB) infection control (IC) are inadequately practiced in most health care facilities in Ethiopia. The aim of this study was to assess the extent of...

    Authors: Asfaw Ayalew, Zewdu Gashu, Tadesse Anteneh, Nebiyu Hiruy, Dereje Habte, Degu Jerene, Genetu Alem, Ilili Jemal, Muluken Melese and Pedro G. Suarez
    Citation: BMC Infectious Diseases 2018 18:557
    Content type: Research article Published on:

  2. Nevirapine has been used as antiretroviral agent since early ‘90. Although nevirapine is not currently recommended in initial anti-HIV regimens, its use remains consistent in a certain number of HIV-1-positive...

    Authors: Andrea Giacomelli, Agostino Riva, Felicia Stefania Falvella, Maria Letizia Oreni, Dario Cattaneo, Stefania Cheli, Giulia Renisi, Valentina Di Cristo, Angelica Lupo, Emilio Clementi, Stefano Rusconi, Massimo Galli and Anna Lisa Ridolfo
    Citation: BMC Infectious Diseases 2018 18:556
    Content type: Research article Published on:

  3. Infection after vertebroplasty (VP) is a rare but serious complication. Previous literatures showed most pathogens for infection after VP were bacteria; tuberculosis (TB) induced infection after VP was extreme...

    Authors: Jen-Chung Liao, Po-Liang Lai, Lih-Hui Chen and Chi-Chien Niu
    Citation: BMC Infectious Diseases 2018 18:555
    Content type: Research article Published on:

  4. Clinical progression of HBV-related liver diseases is largely associated with the activity of HBV-specific T cells. Soluble fibrinogen-like protein 2 (sFGL2), mainly secreted by T cells, is an important effect...

    Authors: Hoang Van Tong, Nguyen Van Ba, Nghiem Xuan Hoan, Mai Thanh Binh, Dao Thanh Quyen, Ho Anh Son, Hoang Van Luong, Do Quyet, Christian G. Meyer, Le Huu Song, Nguyen Linh Toan and Thirumalaisamy P. Velavan
    Citation: BMC Infectious Diseases 2018 18:553
    Content type: Research article Published on:

  5. Genetic mutations that reduce intracellular superoxide production by granulocytes causes chronic granulomatous disease (CGD). These patients suffer from frequent and severe bacterial and fungal infections thro...

    Authors: Esmaeil Mortaz, Somayeh Sarhifynia, Majid Marjani, Afshin Moniri, Davood Mansouri, Payam Mehrian, Karin van Leeuwen, Dirk Roos, Johan Garssen, Ian M. Adcock and Payam Tabarsi
    Citation: BMC Infectious Diseases 2018 18:552
    Content type: Case report Published on:

  7. The Study of Healthcare Personnel with Influenza and other Respiratory Viruses in Israel (SHIRI) prospectively follows a cohort of healthcare personnel (HCP) in two hospitals in Israel. SHIRI will describe the fr...

    Authors: Avital Hirsch, Mark A. Katz, Alon Laufer Peretz, David Greenberg, Rachael Wendlandt, Yonat Shemer Avni, Gabriella Newes-Adeyi, Ilan Gofer, Maya Leventer-Roberts, Nadav Davidovitch, Anat Rosenthal, Rachel Gur-Arie, Tomer Hertz, Aharona Glatman-Freedman, Arnold S. Monto, Eduardo Azziz-Baumgartner…
    Citation: BMC Infectious Diseases 2018 18:550
    Content type: Study protocol Published on:

  8. Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with simila...

    Authors: Simon C. Masha, Piet Cools, Patrick Descheemaeker, Marijke Reynders, Eduard J. Sanders and Mario Vaneechoutte
    Citation: BMC Infectious Diseases 2018 18:549
    Content type: Research article Published on:

  9. On 28 March, 2016, the Ministry of Health received a report on three deaths from an unknown disease characterized by fever, jaundice, and hemorrhage which occurred within a one-month period in the same family ...

    Authors: Leocadia Kwagonza, Ben Masiira, Henry Kyobe-Bosa, Daniel Kadobera, Emily B. Atuheire, Bernard Lubwama, Atek Kagirita, Edson Katushabe, John T. Kayiwa, Julius J. Lutwama, Joseph C. Ojwang, Issa Makumbi, Alex Riolexus Ario, Jeff Borchert and Bao-Ping Zhu
    Citation: BMC Infectious Diseases 2018 18:548
    Content type: Research article Published on:

  10. The Leuconostoc mesenteroides are members of the Streptococcae family and currently has been recognized as potential pathogens. This case describes a bacteremia caused by L. mesenteroides in an immunocompetent pa...

    Authors: Mayra Gonçalves Menegueti, Gilberto Gambero Gaspar, Ana Maria Laus, Anibal Basile-Filho, Fernando Bellissimo-Rodrigues and Maria Auxiliadora-Martins
    Citation: BMC Infectious Diseases 2018 18:547
    Content type: Case report Published on:

  11. In recent decades the epidemic of asymptomatic sexually transmitted infections has extended deep into Brazil, including small towns and rural areas. The purpose of this study was to investigate the epidemiolog...

    Authors: Déborah Ferreira Noronha de Castro Rocha, Luana Rocha da Cunha Rosa, Carla de Almeida Silva, Brunna Rodrigues de Oliveira, Thaynara Lorrane Silva Martins, Regina Maria Bringel Martins, Marcos André de Matos, Megmar Aparecida dos Santos Carneiro, Juliana Pontes Soares, Ana Cristina de Oliveira e Silva, Márcia Maria de Souza, Robert L. Cook, Karlla Antonieta Amorim Caetano and Sheila Araujo Teles
    Citation: BMC Infectious Diseases 2018 18:546
    Content type: Research article Published on:

  12. The East African region is endemic with multiple zoonotic diseases and is one of the hotspots for emerging infectious zoonotic diseases with reported multiple outbreaks of epidemic diseases such as Ebola, Marb...

    Authors: Naomi Kemunto, Eddy Mogoa, Eric Osoro, Austin Bitek, M. Kariuki Njenga and S. M. Thumbi
    Citation: BMC Infectious Diseases 2018 18:545
    Content type: Research article Published on:

  13. Classification of pathogenic Escherichia coli (E. coli) has traditionally relied on detecting specific virulence associated genes (VAGs) or combinations thereof. For E. coli isolated from faecal samples, the pres...

    Authors: Bjørn-Arne Lindstedt, Misti D. Finton, Davide Porcellato and Lin T. Brandal
    Citation: BMC Infectious Diseases 2018 18:544
    Content type: Research article Published on:

  14. China had the third highest burden of tuberculosis population in the world. Bone and joint tuberculosis was a major part and its characteristics were rarely discussed before. This study was designed to review ...

    Authors: Yun Qian, Qixin Han, Wenjun Liu, Wei-En Yuan and Cunyi Fan
    Citation: BMC Infectious Diseases 2018 18:543
    Content type: Research article Published on:

  15. Enteric viruses in surface water pose considerable risk to morbidity in populations living around water catchments and promote outbreaks of waterborne diseases. However, due to poor understanding of the correl...

    Authors: Jing Miao, Xuan Guo, Weili Liu, Dong Yang, Zhiqiang Shen, Zhigang Qiu, Xiang Chen, Kunming Zhang, Hui Hu, Jing Yin, Zhongwei Yang, Junwen Li and Min Jin
    Citation: BMC Infectious Diseases 2018 18:542
    Content type: Research article Published on:

  16. Increasing human immunodeficiency virus (HIV) testing is critical for HIV control. This study aimed to evaluate the interaction between social norms and self-efficacy on HIV testing among Chinese men who have ...

    Authors: Peizhen Zhao, Li Liu, Ye Zhang, Huanhuan Cheng, Bolin Cao, Chuncheng Liu, Cheng Wang, Bin Yang, Chongyi Wei, Joseph D. Tucker and Weiming Tang
    Citation: BMC Infectious Diseases 2018 18:541
    Content type: Research article Published on:

  17. Fomite mediated transmission can be an important pathway causing significant disease transmission in number of settings such as schools, daycare centers, and long-term care facilities. The importance of these ...

    Authors: Alicia N.M. Kraay, Michael A.L. Hayashi, Nancy Hernandez-Ceron, Ian H. Spicknall, Marisa C. Eisenberg, Rafael Meza and Joseph N.S. Eisenberg
    Citation: BMC Infectious Diseases 2018 18:540
    Content type: Research article Published on:

  18. Incarcerated people carry a high burden of infection, including blood-borne diseases (BBDs). It is also known that one million people contract a sexually transmitted infection (STI) every day worldwide, which ...

    Authors: Komal Chacowry Pala, Stéphanie Baggio, Nguyen Toan Tran, François Girardin, Hans Wolff and Laurent Gétaz
    Citation: BMC Infectious Diseases 2018 18:539
    Content type: Research article Published on:

  19. In the Republic of Congo, artemisinin-based combinations have been recommended for the treatment of uncomplicated malaria since 2006. However, the emergence of resistant parasites again these combinations in S...

    Authors: Pembe Issamou Mayengue, Roch Fabien Niama, Dezi Kouhounina Batsimba, Alida Malonga-Massanga, Igor Louzolo, Nadia Claricelle Loukabou Bongolo, Lucette Macosso, Reyna Ibara Ottia, Ghyslain Kimbassa Ngoma, Louis Régis Dossou-Yovo, Brice Pembet Singana, Gabriel Ahombo, Géril Sekangue Obili, Simon Charles Kobawila and Henri Joseph Parra
    Citation: BMC Infectious Diseases 2018 18:538
    Content type: Research article Published on:

  20. In recent years, metagenomic Next-Generation Sequencing (mNGS) has increasingly been used for an accurate assumption-free virological diagnosis. However, the systematic workflow evaluation on clinical respirat...

    Authors: A. Bal, M. Pichon, C. Picard, J. S. Casalegno, M. Valette, I. Schuffenecker, L. Billard, S. Vallet, G. Vilchez, V. Cheynet, G. Oriol, S. Trouillet-Assant, Y. Gillet, B. Lina, K. Brengel-Pesce, F. Morfin…
    Citation: BMC Infectious Diseases 2018 18:537
    Content type: Technical advance Published on:

  21. Patients with HIV-associated tuberculosis (TB) often have their TB and HIV managed in separate vertical programs that offer care for each disease with little coordination. Such “siloed” approaches are associat...

    Authors: Michael E Herce, Jill Morse, Dora Luhanga, Jennifer Harris, Helene J Smith, Stable Besa, Graham Samungole, Nzali Kancheya, Monde Muyoyeta and Stewart E Reid
    Citation: BMC Infectious Diseases 2018 18:536
    Content type: Research article Published on:

  22. Community acquired bloodstream infection (CABSI) in low- and middle income countries is associated with a high mortality. This study describes the clinical manifestations, laboratory findings and correlation o...

    Authors: Vu Quoc Dat, Nguyen Thanh Long, Vu Ngoc Hieu, Nguyen Dinh Hong Phuc, Nguyen Van Kinh, Nguyen Vu Trung, H. Rogier van Doorn, Ana Bonell and Behzad Nadjm
    Citation: BMC Infectious Diseases 2018 18:535
    Content type: Research article Published on:

  23. A population-based study of Chlamydia trachomatis (CT) infections is essential in designing a specific control program; however, no large investigation of CT infections among the general population in mainland Ch...

    Authors: Pengcheng Huai, Furong Li, Zhen Li, Lele Sun, Xi’an Fu, Qing Pan, Gongqi Yu, Zemin Chai, Tongsheng Chu, Zihao Mi, Fangfang Bao, Honglei Wang, Bingni Zhou, Chuan Wang, Yonghu Sun, Guiye Niu…
    Citation: BMC Infectious Diseases 2018 18:534
    Content type: Research article Published on:

  24. Lifelong antiretroviral therapy for HIV infected pregnant and lactating women (Option B+) has been rapidly scaled up but there are concerns about poor retention of women initiating treatment. However, facility...

    Authors: George Kiwanuka, Noah Kiwanuka, Fiston Muneza, Juliet Nabirye, Frederick Oporia, Magdalene A. Odikro, Barbara Castelnuovo and Rhoda K. Wanyenze
    Citation: BMC Infectious Diseases 2018 18:533
    Content type: Research article Published on:

  25. Injection drug use (IDU) is a growing public health threat in Virginia, though there is limited knowledge of related morbidity. The purpose of this study was to describe the temporal, geographic and clinical t...

    Authors: Megan E. Gray, Elizabeth T. Rogawski McQuade, W. Michael Scheld and Rebecca A. Dillingham
    Citation: BMC Infectious Diseases 2018 18:532
    Content type: Research article Published on:

  26. Among men who have sex with men (MSM) in the UK, an estimated 28% have never tested for HIV and only 27% of those at higher risk test at least every 6 months. HIV self-testing (HIVST), where the person takes t...

    Authors: Michelle M. Gabriel, David T. Dunn, Andrew Speakman, Leanne McCabe, Denise Ward, T. Charles Witzel, Justin Harbottle, Simon Collins, Mitzy Gafos, Fiona M. Burns, Fiona C. Lampe, Peter Weatherburn, Andrew Phillips, Sheena McCormack and Alison J. Rodger
    Citation: BMC Infectious Diseases 2018 18:531
    Content type: Study protocol Published on:

  27. The outcome of lung nodule(s) with histopathological findings suggestive of tuberculosis (TB) but lack of microbiologic confirmation remains unclear. Whether these patients require anti-TB treatment remains un...

    Authors: Che-Liang Chung, Yen-Fu Chen, Yen-Ting Lin, Jann-Yuan Wang, Shuenn-Wen Kuo and Jin-Shing Chen
    Citation: BMC Infectious Diseases 2018 18:530
    Content type: Research article Published on:

  28. Adenoviruses (AdV) are non-enveloped, double-stranded DNA viruses with multiple serotypes, which cause a variety of end-organ disease in both immunocompetent and immunocompromised individuals. Some adenoviruse...

    Authors: Rhiannon Ions, Manjith Narayanan, Michael Browning, Erol A. Gaillard, Gary Stiefel and Julian W. Tang
    Citation: BMC Infectious Diseases 2018 18:529
    Content type: Case report Published on:

  29. Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel bunyavirus named SFTS virus (SFTSV), which is classified into the genus Phlebovirus and family Phenuiviridae....

    Authors: Jinjing Zhang, Xiaojing Yan, Yan Li, Ran Gao, Pingping Wang and Wenbin Mo
    Citation: BMC Infectious Diseases 2018 18:528
    Content type: Case report Published on:

  30. Vietnam is endemic for taeniasis and T. solium cysticercosis. Despite this, information on the epidemiological characteristics of the diseases in the Central Highlands of Vietnam are poorly described. The aims of...

    Authors: Dinh Ng-Nguyen, Mark Anthony Stevenson, Kathleen Breen, Trong Van Phan, Van-Anh Thi Nguyen, Tinh Van Vo and Rebecca Justine Traub
    Citation: BMC Infectious Diseases 2018 18:527
    Content type: Research article Published on:

  31. Rabies is a significant public health problem in China. Previous spatial epidemiological studies have helped understand the epidemiology of animal and human rabies in China. However, quantification of effects ...

    Authors: Danhuai Guo, Wenwu Yin, Hongjie Yu, Jean-Claude Thill, Weishi Yang, Feng Chen and Deqiang Wang
    Citation: BMC Infectious Diseases 2018 18:526
    Content type: Research article Published on:

  32. The effects of maternal influenza infection on the fetus remain unclear. We studied mild influenza and influenza antibodies in relation to birth weight and risks of pre-eclampsia, preterm birth (PTB), and smal...

    Authors: Ida Laake, Gro Tunheim, Anna Hayman Robertson, Olav Hungnes, Kristian Waalen, Siri E. Håberg, Siri Mjaaland and Lill Trogstad
    Citation: BMC Infectious Diseases 2018 18:525
    Content type: Research article Published on:

  33. The prevalence of extended-spectrum β-lactamases (ESBLs) have been reported in clinical isolates obtained from various hospitals in Ethiopia. However, there is no data on the prevalence and antibiotic suscepti...

    Authors: Ahmed Zeynudin, Michael Pritsch, Sören Schubert, Maxim Messerer, Gabriele Liegl, Michael Hoelscher, Tefara Belachew and Andreas Wieser
    Citation: BMC Infectious Diseases 2018 18:524
    Content type: Research article Published on:

  34. Gemella bergeri is one of the nine species of the genus Gemella and is relatively difficult to identify. We herein describe the first case of septic shock due to a Gemella bergeri coinfection with Eikenella corro...

    Authors: Toshinobu Yamagishi, Mayu Hikone, Kazuhiro Sugiyama, Takahiro Tanabe, Yasuhiro Wada, Michiko Furugaito, Yuko Arai, Yutaka Uzawa, Ryo Mizushima, Keisuke Kamada, Yasutomo Itakura, Shigekazu Iguchi, Atsushi Yoshida, Ken Kikuchi and Yuichi Hamabe
    Citation: BMC Infectious Diseases 2018 18:523
    Content type: Case report Published on:

  35. Aerococcus urinae is a gram-positive, alpha-hemolytic coccus bacterium primarily implicated in less than 1 % of all symptomatic urinary tract infections. Risk factors for disease include male gender, advanced age...

    Authors: Joseph M. Yabes, Serafim Perdikis, David B. Graham and Ana Markelz
    Citation: BMC Infectious Diseases 2018 18:522
    Content type: Case report Published on:

  36. Human norovirus is the leading cause of viral gastroenteritis globally, and the GII.4 has been the most predominant genotype for decades. This genotype has numerous variants that have caused repeated epidemics...

    Authors: Nicholas Petronella, Jennifer Ronholm, Menka Suresh, Jennifer Harlow, Oksana Mykytczuk, Nathalie Corneau, Sabah Bidawid and Neda Nasheri
    Citation: BMC Infectious Diseases 2018 18:521
    Content type: Research article Published on:

  37. Cryptococcal meningitis remains the leading cause of adult meningitis in Sub-Saharan Africa. Immune Reconstitution Inflammatory Syndrome (IRIS) following anti-retroviral therapy (ART) initiation is an importan...

    Authors: Jayne P. Ellis, Newton Kalata, Elizabeth C. Joekes, Samuel Kampondeni, Laura A. Benjamin, Thomas S. Harrison, David G. Lalloo and Robert S. Heyderman
    Citation: BMC Infectious Diseases 2018 18:520
    Content type: Case report Published on:

  38. Prenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide post-exposure prophylaxis. We examined the association between...

    Authors: Vera Ehrenstein, Nickolaj Risbo Kristensen, Brigitta Ursula Monz, Barry Clinch, Andy Kenwright and Henrik Toft Sørensen
    Citation: BMC Infectious Diseases 2018 18:519
    Content type: Research article Published on:

  39. Possible cardiotoxicity of sofosbuvir in humans has not been demonstrated yet. Also, since HCV can exert deleterious effects on hearth function, it is of interest to know whether HCV eradication provides any b...

    Authors: Maria Mazzitelli, Carlo Torti, Jolanda Sabatino, Greta Luana D’Ascoli, Chiara Costa, Vincenzo Pisani, Elena Raffetti, Salvatore De Rosa, Alessio Strazzulla, Alfredo Focà, Maria Carla Liberto and Ciro Indolfi
    Citation: BMC Infectious Diseases 2018 18:518
    Content type: Research article Published on:

  40. The first step of designing any genome-based molecular diagnostic test is to find a specific target sequence. The modified genome comparison method is one of the easiest and most comprehensive ways to achieve ...

    Authors: Alireza Neshani, Reza Kamali Kakhki, Mojtaba Sankian, Hosna Zare, Amin Hooshyar Chichaklu, Mahsa Sayyadi and Kiarash Ghazvini
    Citation: BMC Infectious Diseases 2018 18:517
    Content type: Research article Published on:

  41. Viral hepatitis is an important public health issue in sub-Saharan Africa. Due to rising mortality from cirrhosis and hepatocellular carcinoma and limited implementation of screening and treatment programmes, ...

    Authors: Alexander J Stockdale, Collins Mitambo, Dean Everett, Anna Maria Geretti and Melita A Gordon
    Citation: BMC Infectious Diseases 2018 18:516
    Content type: Research article Published on:

  42. Early diagnosis of tuberculosis (TB) and involvement of the public-private partnership are critical to eradicate TB. Patients need to receive proper treatment through the National Tuberculosis Control Programm...

    Authors: K. A. T. M. Ehsanul Huq, Michiko Moriyama, Khalequ Zaman, Mohammod Jobayer Chisti, Julie Long, Akramul Islam, Shahed Hossain, Habiba Shirin, Mohammad Jyoti Raihan, Sajeda Chowdhury and Md Moshiur Rahman
    Citation: BMC Infectious Diseases 2018 18:515
    Content type: Research article Published on:

  43. Incomplete virologic suppression results in mutations associated with resistance and is a major obstacle to disease control. We analyzed the genotypic profiles of HIV-1 patients at the time of the first virolo...

    Authors: Marta Iglis Oliveira, Valter Romão de Souza Junior, Claudia Fernanda de Lacerda Vidal and Paulo Sérgio Ramos de Araújo
    Citation: BMC Infectious Diseases 2018 18:514
    Content type: Research article Published on:

  44. We aimed to identify the main spreading clones, describe the resistance mechanisms associated with carbapenem- and/or multidrug-resistant P. aeruginosa and characterize patients at risk of acquiring these strains...

    Authors: Kaidi Telling, Mailis Laht, Age Brauer, Maido Remm, Veljo Kisand, Matti Maimets, Tanel Tenson and Irja Lutsar
    Citation: BMC Infectious Diseases 2018 18:513
    Content type: Research article Published on:

  46. Clinical studies and mathematical simulation suggest that active surveillance with contact isolation is associated with reduced vancomycin-resistant enterococci (VRE) prevalence compared to passive surveillanc...

    Authors: Agnes Loo Yee Cheah, Allen C. Cheng, Denis Spelman, Roger L. Nation, David C. M. Kong and Emma S. McBryde
    Citation: BMC Infectious Diseases 2018 18:511
    Content type: Research article Published on:

  47. Respiratory tract infections (RTIs) are the most common illness in children, and rapid diagnosis is required for the optimal management of RTIs, especially severe infections.

    Authors: Jin Li, Yue Tao, Mingyu Tang, Bailu Du, Yijun Xia, Xi Mo and Qing Cao
    Citation: BMC Infectious Diseases 2018 18:510
    Content type: Research article Published on:

  48. Human papillomavirus (HPV), Epstein-Barr virus (EBV) and herpes simplex virus (HSV) cause sexually transmitted diseases (STDs) that are frequently found in men who have sex with men (MSM) with human immunodeficie...

    Authors: Jureeporn Chuerduangphui, Kanisara Proyrungroj, Chamsai Pientong, Saowarop Hinkan, Jiratha Budkaew, Charinya Pimson, Bandit Chumworathayi, Ploenpit Hanond and Tipaya Ekalaksananan
    Citation: BMC Infectious Diseases 2018 18:509
    Content type: Research article Published on:

  49. Antistaphylococcal penicillins (ASPs) and cefazolin have become the most frequent choices for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) infections. However, the best therapeutic agent ...

    Authors: Changcheng Shi, Yubo Xiao, Qi Zhang, Qingyu Li, Fei Wang, Jing Wu and Nengming Lin
    Citation: BMC Infectious Diseases 2018 18:508
    Content type: Research article Published on:

  50. The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-expo...

    Authors: Liesbeth F Mieras, Anna T Taal, Wim H van Brakel, Emmanuelle Cambau, Paul R Saunderson, W Cairns S Smith, Cita Rosita S Prakoeswa, Linda Astari, David M Scollard, Dejair Caitano do Nascimento, Jacques Grosset, Hemanta K Kar, Shinzo Izumi, Laura Gillini, Marcos C L Virmond and Marieke G G Sturkenboom
    Citation: BMC Infectious Diseases 2018 18:506
    Content type: Debate Published on:

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