Volume 12 Supplement 2
Proceedings of the Second Workshop of the Regional Study Group on HCV in the Calabria Region (Southern Italy). The virus-host-therapy pathway in HCV disease management: from bench to bedside in the era of Directly Acting Antivirals
Proceedings
Edited by Alfredo Focà, Carlo Torti and Giampiero Carosi
Publication of this supplement was partly supported by an unrestricted grant provided by Roche. The articles were independently prepared by the authors with no input from Roche. Roche were not involved in selecting the articles for the supplement.
Second Workshop of the Regional Study Group on HCV in the Calabria Region (Southern Italy). The virus-host-therapy pathway in HCV disease management: from bench to bedside in the era of Directly Acting Antivirals.
Catanzaro, Italy16 October 2012
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Citation: BMC Infectious Diseases 2012 12(Suppl 2):S1
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Chronic HCV infection: epidemiological and clinical relevance
Hepatitis C virus (HCV), first recognized as a cause of transfusion-associated acute and chronic hepatitis in 1989, plays a major role as a cause of chronic liver injury, with potential for neoplastic degenera...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S2 -
Therapeutic algorithms for chronic hepatitis C in the DAA era during the current economic crisis: whom to treat? How to treat? When to treat?
The advent of triple therapy (TT) with first-generation protease inhibitors boceprevir (BOC) and telaprevir (TVR) in addition to pegylated interferon and ribavirin resulted in a significant gain in terms of su...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S3 -
Epidemiological features and specificities of HCV infection: a hospital-based cohort study in a university medical center of Calabria region
The epidemiological status of HCV in Europe, and in particular in Mediterranean countries, is continuously evolving. The genotype distribution is related to improvement of healthcare conditions, expansion of i...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S4 -
Phylogeny and phylodinamic of Hepatitis C in Italy
Hepatitis C virus infection (HCV) is one of the most pressing health emergencies in the world with a global prevalence of about 170 million people chronically infected worldwide. In Europe, Italy has the highe...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S5 -
Natural history and clinical response: “It’s the virus, stupid, or is it the host?”
A major goal of modern medicine is the application of personalized therapies, consisting of decisions and practices tailored to the individual patient. Information about genetic variants, either mutant or poly...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S6 -
Top topics in HCV research arena
A significant improvement in the rate of eradication of Hepatitis C Virus Genotype 1 has been achieved with the addition of Boceprevir and Telaprevir to pegylated interferon and ribavirin. These two drugs are ...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S7 -
Molecular diagnostic and predictive tests in the evolution of chronic hepatitis C anti-viral therapies
Since the discovery of HCV, polymerase chain reaction (PCR) has significantly contributed to the understanding of the virus life cycle and its replicative kinetics during anti-viral therapy. Parallel to the pr...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S8 -
Future research and collaboration: the “SINERGIE” project on HCV (South Italian Network for Rational Guidelines and International Epidemiology)
The SINERGIE (South Italian Network for Rational Guidelines and International Epidemiology) project is intended to set up a collaborative network comprising virologists, clinicians and public health officials ...
Citation: BMC Infectious Diseases 2012 12(Suppl 2):S9
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