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Table 3 Pretreatment characteristics of HCV patients associated with Hb reduction ≥ 2 g/dl compared to pretreatment Hb value

From: Impact of ITPA gene polymorphism for predicting anemia and treatment outcome in HCV infected patients taking Sofosbuvir Ribavirin therapy

Pretreatment characteristics of HCV patients

Odd ratio (95% CI)

P-value

Age of patient

1.07 (1.03–1.11)

0.00

Patient gender

0.59 (0.21–1.68)

0.33

ITPA rs1127354

4.86 (1.79–13.2)

0.00

ITPA rs7270101

0.63 (0.11–3.44)

0.59

Body mass index

0.89 (0.81–0.97)

0.01

Viral load

1.00 (1.00–1.00)

0.34

White blood cell count

1.05 (0.87–1.26)

0.60

Red blood cell count (1012 /L)

0.00 (0.00- 45.6)

0.14

Hemoglobin

71.9 (0.49–10,558)

0.04

Platelet

0.99 (0.98–1.0)

0.15

Aspartate Aminotransferase

1.013 (0.99–1.03)

0.16

Alanine aminotransferase

0.98 (0.96–1.00)

0.18

Bilirubin (Total)

0.24 (0.04–1.25)

0.09

Serum creatinine

0.43 (0.01–9.65)

0.59

Serum urea

0.92 (0.83–1.02)

0.11