Skip to main content

Table 1 Demographic profile of HCV patients (ITPA rs1127354-CC and Non-CC genotype)

From: Impact of ITPA gene polymorphism for predicting anemia and treatment outcome in HCV infected patients taking Sofosbuvir Ribavirin therapy

Variable

CC genotype

Mean ± SD

Non-CC genotype

Mean ± SD

P-value

Age

41.3 ± 10.2 (21–60)

42.5 ± 12.2(21–59)

0.415

Gender Male/Female

58(52.3%)/53(74.7%)

24(61.5%)/15(38.5%)

0.280

Body mass index

26.5 ± 4.8 (13.2–37.1)

25.3 ± 3.7(20-34.6)

0.146

Hemoglobin g/dl

13.2 ± 1.1(11-16.1)

13.2 ± 1.3 (11.8–16.1)

0.67

HCV RNA by PCR (IU/ml)

2.8 × 106 ± 5.8 × 106 (7525-32367153)

2.6 × 106 ± 3.9 × 106

(6601-13032163)

0.839

Red blood cell count (1012 /L)

4.3 ± 0.3 (3.6–5.3)

4.3 ± 0.4 (3.9–43)

0.89

Hematocrit l/l

39.3 ± 3.4 (34–48)

38.7 ± 3.7(35–49)

0.115

Total leukocyte counts (IU/L)

7.3 ± 2.2 (3.5–15.5)

7.7 ± 2.3 (3.9–13.1)

0.323

Platelets 109 cells/L

224 ± 60 (100–400)

204 ± 66 (100–401)

0.43

Serum Urea mg/dl

28.5 ± 4.4 (19–44)

28 ± 4.7 (21–39)

0.840

Serum creatinine mg/dl

0.7 ± 0.1 (0.5–1.4)

0.7 ± 0.1 (0.5-1.0)

0.890

Total Bilirubin (mg/dl)

0.6 ± 0.2 (0.4–1.5)

0.7 ± 0.4 (0.4–1.9)

0.958

ALT (IU/L)

68 ± 42 (19–225)

72 ± 37 (24–177)

0.342

AST (IU/L)

69 ± 48.1 (22–261)

73 ± 45 (29–201)

0.395

  1. Abbreviations: Aspartate amino transferase (AST), Alanine aminotransferase (ALT), Polymerase chain reaction (PCR), Standard deviation (SD)