Molecular diagnosis, phylogenetic analysis, and antifungal susceptibility profiles of Candida species isolated from neutropenic oncological patients

Table 4 MIC profiles of antifungal susceptibility testing (AFST).

Candida spp	Antifungal	MIC Range	GM	MIC50	MIC90	MIC (µg/mL) [n]
Candida spp	Antifungal	MIC Range	GM	MIC50	MIC90	16	8	4	2	1	0.5	0.25	0.12	0.06	0.03	0.015
C. albicans (n = 16)	CSP	0.015 − 0.5	0.082	0.06	0.375	NA	0	0	0	0	2	2	2	6	3	1
C. albicans (n = 16)	VRC	0.03-2.0	0.116	0.12	0.375	0	0	0	1	0	1	2	5	5	2	NA
C. glabrata (n = 10)	CSP	0.015–0.25	0.064	0.06	0.133	NA	0	0	0	0	0	1	3	3	2	1
C. glabrata (n = 10)	VRC	0.06-1.0	0.173	0.185	0.55	0	0	0	0	1	2	2	1	4	0	NA
C. krusei (n = 4)	CSP	0.03–0.06	0.05			NA	0	0	0	0	0	0	0	3	1	0
C. krusei (n = 4)	VRC	0.25-1	0.294			0	0	0	0	2	1	1	0	0	0	NA
C. parapsilosis (n = 2)	CSP	1–4	2			NA	0	1	0	1	0	0	0	0	0	0
C. parapsilosis (n = 2)	VRC	0.12–0.25	0.173			0	0	0	0	0	0	1	1	0	0	NA
C. tropicalis (n = 1)	CSP	0.12	0.12			NA	0	0	0	0	0	0	1	0	0	0
C. tropicalis (n = 1)	VRC	0.5	0.5			0	0	0	0	0	1	0	0	0	0	NA
C. lambica (n = 1)	CSP	0.12	0.12			NA	0	0	0	0	0	0	1	0	0	0
C. lambica (n = 1)	VRC	0.5	0.5			0	0	0	0	0	1	0	0	0	0	NA

MIC: minimum inhibitory concentration, GM: geometric mean, CSP: caspofungin, VRC: voriconazole, NA: not applicable

ISSN: 1471-2334